Memorize This... Renal Physiology

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Memorize this‌ Renal Physiology Percent of total body weight that is Total Body Water (TBW)

60%

TBW is highest in

newborns and adult males

TBW is lowest in

adult females and adults with large amounts of adipose tissue

ICF comprises how much of TBW

2/3

Major cations of ICF

K+ and Mg2+

Major anions of ICF

protein and organic phosphates

ECF comprises how much of TBW

1/3

ECF is composed of

interstitial fluid and plasma

Major cation of ECF

Na+

Major anions of ECF

Cl- and HCO3-

How much of ECF is plasma?

1/4

How much of ECF is interstitial fluid?

3/4

An ultrafiltrate of plasma (has little protein)

interstitial fluid, bowman space

Steady state Osmolarities of ECF and ICF

Equal (about 295 mOsm/Kg water)

How equality of Concentration between compartments is achieved?

Water shifts (first response). Volume compartments change. Increase in ECF volume; decrease in hematocrit Decrease in ECF volume; increase in hematocrit Increase in ECF volume, ECF Osmolarity, serum Na+ conc.; decrease in ICF volume, Hct decreased

Isomotic volume expansion Isomotic volume contraction Hyperosmotic volume expansion


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