3716 oncology a5 r3

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Oncology Oncology

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Infectious Diseases

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CNS/Pain

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Respiratory

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Oncology

Maximising Opportunities Overcoming Challenges Oncology drug development is a demanding, complicated and highly competitive area. While there has never been as much opportunity and promise for patients, the challenges to achieve market success are ever increasing. At TranScrip we are helping our biotech and pharma clients seize opportunities, address challenges and succeed in realising their drug development or lifecycle management goals by continually adapting and adopting new effective ways to achieve them.

Internal Medicine

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Diverse programmes: Effective execution

A snapshot of our recent projects HDAC INHIBITOR

TK3 INHIBITOR

IMMUNOTHERAPY

CYTOTOXIC CONJUGATE

MODIFIED CYTOTOXIC

VARIOUS PRODUCTS

Clinical development and regulatory affairs support for a programme in prostate cancer.

Medical monitoring for acute myeloid leukaemia programme.

Medical monitoring for a global phase III glioblastoma programme.

Support for clinical development of reformulated compound for the treatment of several cancers.

Phase III data interpretation and presentation to regulatory authorities to support both MAA and NDA.

Strategy and design of Phase II/III programme and regulatory interactions in a variety of cancers.

SME

TRANSLATIONAL

CRO

CRO

CLINICAL DEVELOPMENT

ANTICANCER VACCINE

PI3 KINASE INHIBITOR

IMMUNOTHERAPY

Ad hoc oncology advice in melanoma.

Assessment of drug-drug interactions and risk profile for potential toxicity for combinations of PI3K inhibitors.

Strategy and design of Phase II/III programme and regulatory interactions in a variety of cancers.

SME

TOP 50 PHARMA

SME

SME

SME

REGISTRATION

NOVEL ANGIOGENESIS INHIBITOR Provision of Pharmacovigilance Director for a phase III clinical trial programme in prostate cancer. MEDIUM PHARMA

TOP 50 PHARMA

MEDICAL AFFAIRS

VEGF TKI

HER 2 INHIBITOR

Medical affairs support for renal cell cancer programme.

Pharmacovigilance and regulatory responsibilities for MAA and NDA in breast cancer.

TOP 50 PHARMA

TOP 50 PHARMA


Insightful collaborations: Seamless integration

PORTFOLIO MANAGEMENT AND COMMERCIAL STRATEGY

ACHIEVING EARLY LICENSE THROUGH NEW REGULATORY PATHWAYS

TIO N

BESPOKE TRAINING PROGRAMMES AND PERI-LAUNCH ACTIVITIES

VAT

RATIONALE CHOICE OF COMBINATION TREATMENTS

NO

RA

DIFFERENTIATING PRODUCT IN CROWDED MARKETS

IN

NAVIGATING THROUGH THE DIVERSITY OF ONCOLOGY SCIENCE

ION

INSIGHTS

INTEG

Working as long-term partners, our oncology teams integrate seamlessly with our clients. We provide effective support by delivering strategic insights and innovative approaches to execution across all aspects of drug development from translational science through to registration and medical affairs, worldwide. Our teams’ expertise covers diverse therapeutic mechanisms including targeted therapy, immunotherapy, vaccines and novel cytotoxics.

TranScrip has a proven track record of achievements that include: Designing and delivering large, complex, cross-functional oncology programmes

Serving as the drug development organisation for small biotech companies

Interpreting ‘difficult’ outcomes in clinical trials and steering discussions with the regulatory authorities

Fielding multi-functional submission teams to author and deliver MAAs and NDAs

Providing management and oversight for all drug safety needs

Designing and delivering tailored training programmes for product launches

Linda Summerton, Head of Oncology Contact Linda to find out more about our expertise and how we can work with you. Email: linda.summerton@transcrip-partners.com Tel: +44 (0)118 963 7846

www.transcrip-partners.com

October 2015

CONTACT INFORMATION


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