3716 respiratory a5 r3

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Oncology

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Infectious Diseases

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CNS/Pain

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Respiratory Respiratory

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Respiratory

Maximising Opportunities Overcoming Challenges Respiratory drug development and commercialisation encompass improvements in existing classes of inhaled treatments as well as novel agents for more severe disease and rare respiratory conditions. Finding effective and safe new classes of drugs to treat asthma and COPD remains difficult. At TranScrip we are helping our biotech and pharma clients seize opportunities, address challenges and succeed in realising their drug development or lifecycle management goals by continually adapting and adopting new effective ways to work.

Internal Medicine

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Diverse programmes: Effective execution

A snapshot of our recent projects COMPLEMENT INHIBITORS Design of phase I clinical programme in asthma. Selection of study sites. Regulatory strategy to support European development.

SME

TRANSLATIONAL

VARIOUS PRODUCTS

CRTH2 ANTAGONIST

Evaluation and preparation of development plans for new therapies in allergy.

Support of phase III study in asthma. Study feasibility and investigator suitability, preparation of investigator training and contingency plans for patient recruitment and retention.

TOP 50 PHARMA

TOP 50 PHARMA

CLINICAL DEVELOPMENT

INHALED PRODUCT

INHALATION DEVICES

Regulatory support, obtaining orphan drug designation for Pulmonary Arterial Hypertension. Medical oversight of clinical trials and support to drug safety activities.

Expert clinical support for the development of inhalation devices for various respiratory indications.

SME

MEDIUM PHARMA

INHALED ANTICHOLINERGIC Regulatory and medical support for an MAA in COPD.

MEDIUM PHARMA

Regulatory support in the preparation of submission dossier in asthma and responses to regulatory questions.

MEDIUM PHARMA

REGISTRATION

INHALED COMBINATION PRODUCT Provided leadership to an integrated (client and TranScrip) regulatory submission team for a new indication in asthma.

TOP 50 PHARMA

PULMONARY ARTERIAL HYPERTENSION

INHALED LABA

Scientific advice for development projects and product positioning.

TOP 50 PHARMA

POST-LICENSING

SURFACTANT

VARIOUS PRODUCTS

Risk Management Plan update for an orphan drug in Respiratory Distress Syndrome in newborns.

Assessing respiratory portfolio for the Japanese and Asian markets.

MEDIUM PHARMA

SME


Insightful collaborations: Seamless integration INSIGHTS

TIO N

DIFFERENTIATING PRODUCTS IN CROWDED MARKETS

TIO

EXPEDITING APPROVAL THROUGH NEW REGULATORY PATHWAYS

VA

PORTFOLIO MANAGEMENT AND COMMERCIAL STRATEGY

NO

SUPPORTING DEVELOPMENT OF ORPHAN DRUGS

IN

RA

BESPOKE TRAINING PROGRAMMES

N

MAXIMISING VALUE OF INNOVATIVE PRODUCTS

INTEG

Working as long-term partners, our respiratory teams integrate seamlessly with our clients. We provide effective support by delivering strategic insights and innovative approaches to all aspects of respiratory drug development, from translational science through to registration and medical affairs, worldwide. Our team’s support development of pharmaceuticals and devices across all major respiratory indications from asthma, COPD, allergy (including food allergy) to orphan indications like cystic fibrosis, idiopathic pulmonary fibrosis and pulmonary arterial hypertension.

TranScrip has a proven track record of achievements that include: Designing and delivering large, complex, cross-functional respiratory programmes

Serving as the drug development organisation for small biotech companies

Interpreting ‘difficult’ outcomes in clinical trials and steering discussions with the regulatory authorities

Fielding multi-functional submission teams to author and deliver MAAs and NDAs

Providing management and oversight for all drug safety needs

Designing and delivering tailored training programmes for product launches

Tim Joslin, Head of Respiratory Contact Tim to find out more about our expertise and how we can work with you. Email: tim.joslin@transcrip-partners.com Tel: +44 (0)118 963 7846

www.transcrip-partners.com

October 2015

CONTACT INFORMATION


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