The thesis is a part of an on-going academic research promoted by the cooperation between Interdepartmental Research Center Urban/Eco (University Federico II of Naples, Italy) and the School of design (Jiangnan University, Wuxi, China). The thesis argues about the evolution of the historical city centre of Wuxi, hand in hand with the industrial development, to understand the conversion process and necessary strategies required to install new architectural programme within the existing industrial sites, recognizing their unique conditions. Embracing multi-scaled approach, the thesis proposes new landscape chances of uses by putting the remains of industrial cores in a network that constitutes a clustering of art, history, leisure and entertainment. Among them, more attention is given to Taibaodun area, main industrial core of Wuxi, and Maoxin site, the former industrial site of Taibaodun area.