MD 1378 | 2012
NEUROMODULATION MARKET – [Spinal Cord Stimulation (SCS), Vagus Nerve Stimulation (VNS), Gastric Electrical Stimulation (GES), Deep Brain Stimulation (DBS), Sacral Nerve Stimulation (SNS) & Transcranial Magnetic Stimulation (TMS)]
– Forecasts to 2017 Report Description
Table of Contents List of Tables Sample Tables Related Reports About MarketsandMarkets
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MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
Report Description Key Take-Aways •
To define and measure the global neuromodulation devices market, which comprises of internal stimulation and external stimulation
•
To analyze the market by identifying various subsegments of the global neuromodulation devices market
•
To forecast the revenue of the global neuromodulation devices market and its various segments
•
To identify major market trends and factors driving or inhibiting the growth of the global neuromodulation devices market and its sub-segments
•
•
To analyze opportunities for stakeholders in the market by identifying high-growth segments
•
To forecast revenue of market segments with respect to four main geographies – North America, Europe, Asia, and Rest of the World (RoW)
•
To strategically profile key players and comprehensively analyze their recent developments, financials, and strategies
•
To track and analyze competitive developments in the global neuromodulation devices market
To strategically analyze each submarket with respect to individual growth trends and contribution to the overall global neuromodulation devices market
Report Description The neuromodulation market is expected to grow at a CAGR of 11.6% in the next five years primarily due to technical advances and patient-friendly techniques such as minimally invasive and non invasive. The market is expected to show promise in therapeutic areas, as it offers relief from chronic pain, incontinence, heart failure, headache, depression, and epilepsy. Moreover, there are few modalities in clinical trials for newer applications, for instance deep brain stimulation for Alzhiemer’s and depression, and vagus nerve stimulation for heart failure. The neuromodulation market is expected to reach $6.8 billion by 2017.
Parkinson’s in the U.S. alone. A wide pool of patients suffering from other conditions such as depression, stroke, anxiety disorders, lower back pain, urinary incontinence, and tremor are also an influential factor in triggering the market towards growth. Treatment for tinnitus represents one of the emerging applications in this market. According to the American Tinnitus Association, about 50 million people suffer from the disease in the U.S. alone. Major players in the market include Medtronic, Inc. (U.S.), Cyberonics, Inc. (U.S.), Boston Scientific Corp. (U.S.), St. Jude Medical, Inc. (U.S.), Enteromedics, Inc. (U.S.), Dynatronics Corp. (U.S.), and Neuronetics (U.S.). Emerging players include Functional Neuromodulation Ltd. (U.S.), MicroTransponder, Inc. (U.S.), Zynex Medical, Inc. (U.S.) and Neurotech SA – a Sorin Group Company (Belgium).
The neuromodulation devices market includes spinal cord stimulation (SCS), deep brain stimulation (DBS), vagus nerve stimulation (VNS), sacral nerve stimulation (SNS), gastric electrical stimulation (GES), and external stimulation devices such as transcranial magnetic stimulation (TMS) and transcutaneous electrical nerve stimulation (TENS). Rapidly aging population and associated diseases like Alzheimer’s, epilepsy, spinal cord injury and Parkinson’s are the prime reasons for the growth of this market. According to the International Neurostimulation Society, about 40-50 million patients worldwide suffer from epilepsy and 1.5 million from
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MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
Report Description Markets Covered The global neuromodulation devices market has been segmented as below:
External Stimulation • By Modality
Internal Stimulation •
§
Transcranial Magnetic Stimulation (TMS)
§
Transcutaneous Electrical Nerve Stimulation (TENS)
By Modality §
Spinal Cord Stimulation (SCS)
By Geography
o Market by Application
•
North America
•
Failed Back Surgery Syndrome
§
U.S.
•
Chronic Pain
§
Canada
•
Ischemia
•
Others §
•
Deep Brain Stimulation (DBS)
o Market by Application
•
Europe §
EU5 (Germany, France, Italy, Spain, U.K.)
§
RoE (Rest of Europe)
Asia
•
Parkinson’s Disease
§
India
•
Alzheimer’s
§
China
•
Dystonia
§
Japan
•
Tremor
§
RoA (Rest of Asia)
•
Depression
•
Others (Chronic Pain & Post Operative Coma) §
•
Sacral Nerve Stimulation (SNS)
o Market by Application •
Urinary Incontinence
•
Fecal Incontinence
Rest of the World (RoW) §
MEA (Middle East & Africa)
§
LatAm (Latin America)
§
Pacific (Australia & New Zealand)
The report does not include: •
The neuromodulator or drug pumps
o Market by Application
•
Respiratory neurostimulation by laparoscopy
•
Epilepsy
•
Cochlear implants and cortical simulators
•
Others
§
§
Vagus Nerve Stimulation (VNS)
Gastric Electrical Stimulation (GES)
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MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
Report Description Research Methodology Market Size Global Neuromodulation Devices Market • A top-down approach was taken to calculate the total neuromodulation devices market and its sub-segments (SCS, DBS, VNS, SNS, GES & TMS) • Volume numbers were arrived at by dividing the total market by the average selling price of a device (ASP) for a particular year • The market numbers were subsequently validated by interviews with industry and domain experts.
Market Share Global Neuromodulation Devices Market
• The market share have been discussed on the basis of actual sales recorded by companies to the total market size • The market share of top players was confirmed from secondary and primary data
Key Data Points from Secondary Sources Market revenue
Market revenue of companies Qualitative information (market dynamics, market trends)
Company financials, magazines, journals, press releases, paid databases, and MnM data repository Annual reports, company websites, public databases, and MnM data repository
Company websites, annual reports, press releases, databases, and MnM data repository
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MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
Report Description Key Data Points from Primary Sources Parameter
Data Points
Global Spinal Cord Neuromodulation device market 2012
~50%
Global Deep Brain Stimulation Market 2012
~ 11%
Global Vagus nerve stimulation Market 2012
~8%
Global Sacral Nerve stimulation Market 2012
~7.5%
Global Transcranial Magnetic stimulation Market 2012
~ 1-2%
Global Transcutaneous Electrical stimulation Market 2012
~ 14%
Assumptions
Prices
The average selling price of neuromodulation device products is considered as same across all geographies
Stakeholders •
Neuromodulation device companies
•
Original equipment manufacturing companies
•
Medical device distributors
•
Healthcare service providers
•
Health insurance players
•
Research and consulting firm
•
Medical Research institutes
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MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
Table of Contents 1. Introduction 1.1 Key Take-aways 1.2 Report Description 1.3 Markets Covered 1.4 Research Methodology 1.4.1 Market size 1.4.2 Market share
16 16 16 18 20 20 20
1.4.3 Key data points from secondary sources 1.4.4 Key data points from primary sources 1.4.5 Assumptions 1.5 Stakeholders
20 21 21 21
2. Executive Summary
22
3. Market Overview
25
3.1 Introduction
26
3.2 Market Segmentation 3.3 Market Dynamics
27 29
3.3.1.5
Investments and funds – an impetus for market growth 3.4 Restraints 3.4.1.1 An unfavorable reimbursement scenario hinders market growth 3.4.1.2 Lack of trained professionals likely to hamper market growth 3.5 Market Share Analysis
3.3.1 Drivers 29 3.3.1.1 Increasing incidence of neurological disorders to spur market growth 29 3.3.1.2 Unprecedented global aging to fuel market growth 29 3.3.1.3 Strong product pipeline to propel the market 30 3.3.1.4 Expanded target applications and new indications are expected to stimulate growth of neuromodulation devices 30
4. Global Neuromodulation Market (Internal & External) 4.1 Introduction 4.2 Internal Stimulation 4.2.1 Spinal Cord Stimulation (SCS) Market 4.2.1.1 Major applications 4.2.1.1.1 Failed back surgery syndrome 4.2.1.1.2 Chronic pain 4.2.1.1.3 Ischemia 4.2.2 Deep Brain Stimulation (DBS) 4.2.2.1 Major applications 4.2.2.1.1 Parkinson’s disease 4.2.2.1.2 Dystonia 4.2.2.1.3 Tremor 4.2.2.1.4 Alzheimer’s
36 37 37 39 40 40 42 42 45 46 47 47
4.2.3 Sacral Nerve Stimulation (SNS) 4.2.3.1 Major applications 4.2.3.1.1 Urine incontinence 4.2.3.1.2 Fecal incontinence 4.2.4 Vagus Nerve Stimulation (VNS) 4.2.4.1 Major applications 4.2.4.1.1 Epilepsy 4.2.4.1.2 Others 4.2.5 Gastric Electrical Stimulation (GES) 4.3 External Stimulation 4.3.1 Transcutaneous Electrical Nerve Stimulation (TENS) 4.3.2 Transcranial Magnetic Stimulation (TMS)
48
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31 32 32 33 33
35 48 51 52 53 53 56 57 58 58 61 61 64
MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
Table of Contents 5. Geographic Analysis 5.1 Introduction 5.2 North America 5.3 Europe
68 69 72 80
5.4 Asia 5.5 Rest of The World
6. Competitive Landscape 6.1 Introduction 6.2 Agreements, Partnerships, Collaborations, Contracts & Joint Ventures 6.3 New Product Launch
106 106
6.4 Expansion 6.5 Other Developments 6.6 Approvals
108 110
7. Company Profiles (Overview, Financials, Products & Services, Strategy, & Developments)* 7.1 7.2 7.3 7.4 7.5 7.6 7.7 7.8 7.9 7.10
ANM Adaptive Neuromodulation Gmbh Biocontrol Medical, Ltd. Boston Scientific Corporation Cerbomed Gmbh Cyberonics, Inc. Endostim, Inc. Enteromedics, Inc. The Magstim Company Limited Medtronic, Inc. Neuronetics, Inc.
87 97
122 125 128 136 139 144 147 150 153 159
7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 7.19
Neuropace, Inc. Neurosigma, Inc. Nevro Corporation Rs Medical Spinal Modulation, Inc. St. Jude Medical Synapse Biomedical, Inc. Uroplasty, Inc. Zynex, Inc.
112 113 114
122 162 164 167 169 172 174 182 184 188
*Details on Financials, Product & Services, Strategy, and Developments might not be captured in case of unlisted companies.
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MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
List of Tables 1 2 3 4
Global Neuromodulation Market, by Procedure, 2010 - 2017 ($Million)
23
Global Neuromodulation Market, by Modality, 2010 - 2017 ($Million)
23
Spinal Cord Stimulation Market, by Geography, 2010 - 2017 ($Million)
38
Spinal Cord Stimulation Market Volume, by Geography, 2010 - 2017 (No of Units)
22
Global Transcranial Magnetic Stimulation Market, by Application, 2010 - 2017 ($Million) 67
23
Neuromodulation Devices Market, by Geography, 2010 - 2017 ($Million) 69
24
External Neuromodulation Devices Market, by Geography, 2010 - 2017 ($Million)
70
Internal Neuromodulation Devices Market, by Geography, 2010 - 2017 ($Million)
71
25 39
5
Global Spinal Cord Stimulation Market, by Application, 2010 - 2017 ($Million) 41
26
Global External Neuromodulation Market, by Modality, 2010 - 2017 ($Million) 71
6
Deep Brain Stimulation Market, by Geography, 2010 - 2017 ($Million)
27
Global External Neuromodulation Devices Market Volume, by Modality, 2010 - 2017 (No of Units) 72
44
7
Deep Brain Stimulation Market Volume, by Geography, 2010 - 2017 (No of Units) 45
28
North America: Neuromodulation Devices Market, by Procedure, 2010 - 2017 ($Million) 73
8
Global Deep Brain Stimulation Market, by Application, 2010 - 2017 ($Million) 46
29
North America: Internal Neuromodulation Devices Market, by Modality, 2010 - 2017 ($Million) 74
9
Sacral Nerve Stimulation Market, by Geography, 2010 - 2017 ($Million)
30 50
Sacral Nerve Stimulation Market Volume, by Geography, 2010 - 2017 (No of Units)
North America: Internal Neuromodulation Devices Market Volume, by Modality, 2010 - 2017 (No. of Units) 75
51
31
Global Sacral Nerve Stimulation Market, by Application, 2010 - 2017 ($Million)
North America: External Neuromodulation Devices Market, by Modality, 2010 - 2017 ($Million) 75
52
32
Vagus Nerve Stimulation Market, by Geography, 2010 - 2017 ($Million)
55
North America: External Neuromodulation Devices Market Volume, by Modality, 2010 - 2017 (No. of Units) 76
33
North America: Spinal Cord Stimulation Market, by Country, 2010 - 2017 ($Million)
76
North America: Deep Brain Stimulation Market, by Country, 2010 - 2017 ($Million)
77
10 11 12 13 14
Vagus Nerve Stimulation Market Volume, by Geography, 2010 - 2017 (No of Units) Global Vagus Nerve Stimulation Market, by Application, 2010 - 2017 ($Million)
56 34 57
15
Gastric Electrical Stimulation Market, by Geography, 2010 - 2017 ($Million) 59
35
North America: Sacral Nerve Stimulation, by Country, 2010 - 2017 ($Million) 77
16
Gastric Electrical Stimulation Market Volume, by Geography, 2010 - 2017 (No of Units)
36
North America: Vagus Nerve Stimulation Market, by Country, 2010 - 2017 ($Million)
17
Global Gastric Electrical Stimulation Market, by Application, 2010-2017 ($Million)
60
78
37
North America: Gastric Electrical Stimulation Market, by Country, 2010 - 2017 ($Million) 78
61
18
Transcutaneous Electrical Nerve Stimulation Market, by Geography, 2010 - 2017 ($Million) 63
38
North America: Transcranial Magnetic Stimulation Market, by Country, 2010 - 2017 ($Million) 79
19
Transcutaneous Electrical Nerve Stimulation Market Volume, by Geography, 2010 - 2017 (No of Units) 64
39
20
Transcranial Magnetic Stimulation Market, by Geography, 2010 - 2017 ($Million)
North America: Transcutaneous Electrical Nerve Stimulation Market, by Country, 2010 - 2017 ($Million)
79
Europe: Neuromodulation Devices Market, by Procedure, 2010 - 2017 ($Million)
81
21
65
40
Transcranial Magnetic Stimulation Market Volume, by Geography, 2010 - 2017 (No of Units) 66
41
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Europe: Internal Neuromodulation Devices Market, by Modality, 2010 - 2017 ($Million) 81
MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
List of Tables 42
Europe: Internal Neuromodulation Devices Market Volume, by Modality, 2010 - 2017 (No. of Units) 82
63
ROW: Internal Neuromodulation Devices Market, by Modality, 2010 - 2017 ($Million) 98
43
Europe: External Neuromodulation Devices Market, by Modality, 2010 - 2017 ($Million) 83
64
ROW: Internal Neuromodulation Devices Market Volume, by Modality, 2010 - 2017 (No. of Units)
44
Europe: External Neuromodulation Devices Market Volume, by Modality, 2010 - 2017 (No. of Units) 83
65
ROW: External Neuromodulation Devices Market, by Modality, 2010 - 2017 ($Million) 99
45
Europe: Spinal Cord Stimulation Market, by Region, 2010 - 2017 ($Million) 84
66
ROW: External Neuromodulation Devices Market Volume, by Modality, 2010 - 2017 (No. of Units) 100
46
Europe: Deep Brain Stimulation Market, by Region, 2010 - 2017 ($Million) 84
67
ROW: Spinal Cord Stimulation Market, by Region, 2010 - 2017 ($Million) 100
47
Europe: Sacral Nerve Stimulation, by Region, 2010 - 2017 ($Million)
68
ROW: Deep Brain Stimulation Market, by Region, 2010 - 2017 ($Million) 101
Europe: Vagus Nerve Stimulation Market, by Region, 2010 - 2017 ($Million) 85
69
ROW: Sacral Nerve Stimulation, by Region, 2010 - 2017 ($Million)
Europe: Gastric Electrical Stimulation Market, by Region, 2010 - 2017 ($Million)
70
ROW: Vagus Nerve Stimulation Market, by Region, 2010 - 2017 ($Million) 102
Europe: Transcranial Magnetic Stimulation Market, by Region, 2010 - 2017 ($Million) 86
71
ROW: Gastric Electrical Stimulation Market, by Region, 2010 - 2017 ($Million)
103
Europe: Transcutaneous Electrical Nerve Stimulation Market, by Region, 2010 - 2017 ($Million) 87
72
ROW: Transcranial Magnetic Stimulation Market, by Region, 2010 - 2017 ($Million)
104
52
Asia: Neuromodulation Devices Market, by Procedure, 2010 - 2017 ($Million) 88
73
ROW: Transcutaneous Electrical Nerve Stimulation Market, by Region, 2010 - 2017 ($Million) 104
53
Asia: Internal Neuromodulation Devices Market, by Modality, 2010 - 2017 ($Million)
74 89
Agreements, Partnerships, Collaborations, Contracts & Joint Ventures, 2010 - 2012 108
Asia: Internal Neuromodulation Devices Market Volume, by Modality, 2010 - 2017 (No. of Units)
75
New Product Launch, 2010 - 2012
110
90
76
Expansion, 2010 - 2012
112
Asia: External Neuromodulation Devices Market, by Modality, 2010 - 2017 ($Million)
90
77
Other Developments, 2010 - 2012
113
Asia: External Neuromodulation Devices Market Volume, by Modality, 2010 - 2017 (No. of Units)
78
Approvals, 2010 - 2012
114
91
79
57
Asia: Spinal Cord Stimulation Market, by Country, 2010 - 2017 ($Million) 92
Boston Scientific Corporation: Total Revenue and R&D Expenditure, 2009 - 2011 ($Million)
129
80
58
Asia: Deep Brain Stimulation Market, by Country, 2010 - 2017 ($Million) 93
Boston Scientific Corporation: Total Revenue, by Segments, 2009 - 2011 ($Million)
129
81
59
Asia: Sacral Nerve Stimulation, by Country, 2010 - 2017 ($Million)
Boston Scientific: Total Revenue, by Geography, 2009 - 2011 ($Million)
130
94
82
Asia: Transcranial Magnetic Stimulation Market, by Country, 2010 - 2017 ($Million)
Cyberonics, Inc.: Total Revenue and R&D Expenditure,2009 - 2011 ($Million)
140
95
83
61
Asia: Transcutaneous Electrical Nerve Stimulation Market, by Country, 2010 - 2017 ($Million) 96
Cyberonics, Inc.: Total Revenue, by Geography, 2009 - 2011 ($Million)
140
84
62
ROW: Neuromodulation Devices Market, by Procedure, 2010 - 2017 ($Million)
Medtronic, Inc.: Total Revenue and R&D Expenditure, 2009 - 2011 ($Million) 154
85
Medtronic, Inc: Total Revenue, by Segments, 2009 - 2011 ($Million)
48 49 50 51
54 55 56
60
85
86
97
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99
102
154
MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
List of Tables 86 87 88
Medtronic, Inc.: Total Revenue, by Geography, 2009 - 2011 ($Million)
155
91
St. Jude Medical, Inc: Total Revenue and R&D Expenditure, 2009 - 2011 ($Million)
175
St. Jude Medical, Inc: Total Revenue, by Segments, 2009 - 2011 ($Million) 175
89
St. Jude Medical, Inc: Total Revenue, by Geography, 2009 - 2011 ($Million) 176
90
Uroplasty, Inc.: Total Revenue and R&D Expenditure, 2010 - 2012 ($Million) 185
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Uroplasty, Inc.: Total Revenue, by Geography, 2010 - 2012 ($Million)
185
92
Zynex, Inc.: Total Revenue and R&D Expenditure, 2009 - 2011 ($Million) 189
93
Zynex, Inc.: Total Revenue, by Segments, 2009 - 2011 ($Million)
189
MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
List of Figures 1
Neuromodulation Market Segmentation
28
2
Market Dynamics
32
3
Neuromodulation Market Share Analysis, by Revenue, 2011
34
4
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Key Growth Strategies, 2010 - 2012
107
MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
Sample Tables Table
Global Neuromodulation Market, By Procedure, 2010 – 2017 ($Million)
Procedure
2010
2011
Total Table
2017
CAGR% (2012-2017)
2017
CAGR% (2012-2017)
s e l b a T e l p m
Internal Stimulation External Stimulation
2012
Sa
Spinal Cord Stimulation Market, By Geography, 2010 – 2017 ($Million)
Region
2010
2011
2012
s e l b a T e l p m
North America Europe
Sa
Asia RoW Total Table
Global Spinal Cord Stimulation Market, By Application, 2010 – 2017 ($Million)
Application Chronic Pain FBSS Ischemic Pain Others
2010
2011
2012
2017
CAGR% (2012-2017)
s e l b a T e l p Sam
Total
Table
Deep Brain Stimulation Market Volume, By Geography, 2010-2017 (No of Units)
Region
2010
2011
s e l b a T e l p m
North America Europe Asia RoW
2012
Sa
Total
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2017
CAGR% (2012-2017)
MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
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MD 1378 | 2012
Neuromodulation Market – Forecasts to 2017
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