MD Anderson Annual Report 2007-2008 by MD Anderson Cancer Center

commitment to research

commitment to the cancer care cycle

Annual Report 2007-2008

Commitment Creates Momentum

commitment to education

commitment to development commitment to outreach

VISION We shall be the premier cancer center in the world, based on the excellence of our people, our researchdriven patient care and our science. We are Making Cancer History速.

MISSION The mission of The University of Texas M. D. Anderson Cancer Center is to eliminate cancer in Texas, the nation and the world through outstanding programs that integrate patient care, research and prevention, and through education for undergraduate and graduate students, trainees, professionals, employees and the public.

President's Message

Commitment to the cancer care cycle

Commitment to research

Commitment to outreach

Commitment to education

Commitment to development

Faculty

70 board of visitors 72 donors 89 financials and statistical data

CORE VALUES Caring By our words and actions, we create a caring environment for everyone.

Integrity We work together to merit the trust of our colleagues and those we serve.

Discovery We embrace creativity and seek new knowledge.

M. D. Anderson Annual Report 2007-2008

A message from the president

If I were to describe the energy and achievements at M. D. Anderson this past year in a single word, that word would be momentum. Sparked by the commitment of our faculty and staff, momentum permeates our endeavors to transform cancer care through research that will have the greatest impact on saving lives and improving the quality of life for patients everywhere. In this annual report, I hope you will see how this energy brings benefit to science and to people around the globe. Our momentum in patient care is designed to broaden the cancer care cycle beyond the innovations in therapy that are M. D. Anderson’s hallmark. We already have extended the cancer care continuum with an ambitious cancer prevention program. Last year, our prevention program was further fueled by a major philanthropic gift and new leadership. At the other end of the continuum of care, we have launched a multi-faceted program — involving hundreds of M. D. Anderson people — to improve the quality of life for cancer survivors.

and now train students in many disciplines at both the undergraduate and graduate level. Our postdoctoral and fellowship training positions are sought by thousands who seek to complete their career preparation at this institution. Our labs also are filled with medical students, high school students and high school teachers, all eager to learn more about cancer. Education extends into the community, and we are making a sizable commitment to becoming an international education and information resource using both traditional and online approaches.

Momentum in research at M. D. Anderson continues to translate the discoveries of our scientists into useful, effective therapies and precise diagnostic and screening tools. Last year, more than 11,000 M. D. Anderson patients took part in clinical trials of potential new therapies, some available nowhere else in the world. We are committed to exploring new approaches to treatment based on the cancer-related genes and proteins unique to each individual. Our scientists and clinicians again have earned the largest investment of National Cancer Institute grant funds, and we have made a significant commitment of funds from M. D. Anderson to support research, as well.

Ours is an ambitious program, and momentum in development helps ensure M. D. Anderson’s ability to continue its mission of Making Cancer History® in patient care, research, education and prevention. We are grateful for the generosity of more than 76,000 donors last year whose support of this institution is essential. In return for the confidence of donors, we are committed to the highest use and most careful stewardship of the funds entrusted to us.

Also new to M. D. Anderson is momentum in outreach to carry our patient care advances and research findings into the community and around the world. Our Center for Global Oncology has partnered with colleagues and institutions in Houston and other states, as well as some of the world’s most important cancer centers and research institutes. We have embraced a global strategy to help others, and we also know we can learn from others. We have significant research teams working to gain a better understanding of the impact of cancer on diverse and often-underserved populations, both in the United States and abroad.

There is far more to say about M. D. Anderson, for we are a world leader in cancer, and our team is tackling one of the world’s great, unsolved health problems with confidence and energy. For now, we hope you find this report provides a glimpse into the successes and challenges that make up the work of our devoted and talented faculty, employees of all types, and volunteers.

John Mendelsohn, M.D. President

M. D. Anderson’s momentum in education is helping the nation prepare for the future by training health care providers and scientists and serving the general public. We have degree-granting status and accreditation,

Commitment to the Cancer Care Cycle

risk assessment and early detection

prevention

Commitment to the Cancer Care Cycle

patient care and safety

symptom management and supportive care

M. D. Anderson Annual Report 2007-2008

pediatric and young adult care

survivorship

At M. D. Anderson, we envision the cancer care cycle before it begins, placing significant emphasis on prevention through screening and risk assessment that often allow for early detection when cancer is the most treatable. Weâ&#x20AC;&#x2122;re also pioneers in research on both common and rare cancers as we work to ensure the best in safe and effective care for children and adults when they enter our doors, no matter what their needs â&#x20AC;&#x201D; from diagnosis and treatment to survivorship, supportive care and symptom management.

Commitment to the Cancer Care Cycle

Progress in cancer care at M. D. Anderson is a given. Faculty leader addresses the â&#x20AC;&#x2DC;howâ&#x20AC;&#x2122; of patient care

by Erika Hargrove

M. D. Anderson Annual Report 2007-2008

Thomas FeelEy, M.D.

The foresight of our leaders, zeal of our researchers and compassion of our clinicians guarantees it. The question for Thomas Feeley, M.D., is not “if” we will progress but “how.” How will we continue to deliver the quality of care our patients deserve in this changing world? A man of many hats, Feeley wears them all in an effort to find the answer. He holds two titles: vice president for medical operations and head of the Division of Anesthesiology and Critical Care. Since joining M. D. Anderson in 1997, he has led a series of efforts that focus on process improvement — the how of getting things done.

The Institute for Cancer Care Excellence is the latest process improvement project under his leadership. Its charge is to study how the cancer care cycle — prevention, intervention and survivorship — is impacted by tests and new treatments, patient safety, information technology, and the need for improved efficiency and reduced cost. It also promises to have the most far-reaching effect of any program he has worked on.

“When it comes to cancer care the predominant focus has been on working toward the cure. The motivation behind the institute is to evaluate all the ways we are addressing the delivery of cancer care in its broadest sense. It should be safe, timely, efficient, effective, equitable and patient-centered,” he says.

Feeley says that the institute is an additional imperative effort. “If we don’t work on the ‘how’ of cancer care, there is the potential that disparities will worsen, and there will not be equal access to optimal cancer treatment.”

Commitment to the Cancer Care Cycle

Momentum in Prevention

New division head Expands prevention efforts Ernest Hawk, M.D., left his post at the National Cancer Institute in December 2007 to join M. D. Anderson as its vice president for cancer prevention and head of the Division of Cancer Prevention and Population Sciences. Trained as a medical oncologist with a specialization in cancers of the gastrointestinal tract, cancer prevention is Hawk’s life work. “Many underestimate the value of taking proactive measures to address cancer prevention,” Hawk says. “Taking part in prevention studies is one way people can take steps to improve their health while generating research results that may increase cancer prevention options for family members and future generations.”

M. D. Anderson Annual Report 2007-2008

Epidemiologist aims to lower risk of recurrence in breast cancer patients By Robin Davidson

While volunteering at a children’s hospital during her junior year at Stanford University, Abenaa Brewster, M.D., witnessed firsthand the care and compassion required by oncologists. Right then, she made the decision to become an oncologist, and she’s never looked back. “While I enjoy epidemiological research and have a fabulous collaborative research team, I derive just as much pleasure from my clinical activities and seeing patients in the Nellie B. Connally Breast Center,” says Brewster, assistant professor in the Department of Clinical Cancer Prevention.

She recently led a team of researchers who studied 2,838 women from the M. D. Anderson Tumor Registry who were originally diagnosed with stage I-III breast cancers and treated with adjuvant systemic therapy, such as chemotherapy and/or tamoxifen.

“Understandably, one of the most common questions posed by breast cancer survivors is ‘What are the chances of it coming back?’ Now we can tell some women within a certain percentage their future risk of recurrence, and clinicians may be able to make more informed decisions regarding prescription of extended adjuvant endocrine therapy for a period of years,” she says. The study also indicated a need for the continued development of risk-reduction strategies for premenopausal breast cancer survivors because of the need for more effective therapies in this younger age group. “The magnitude of risk of recurrence should indicate a need for us to consider extended endocrine treatment for eligible women to further lower their risks,” Brewster says. “My research in molecular epidemiology is focused on using hospital- and population-based cancer studies to identify epidemiological and biological factors that are associated with breast cancer risk and survival. These novel studies are providing important insights into how a patient’s lifestyle and genetic make-up determine her risk of having a poorer chance of survival after a diagnosis of breast cancer and will serve to more effectively personalize cancer care.”

Abenaa Brewster, M.D.

Ethics, compliance key in clinical trials To enhance the understanding of federal regulations related to clinical cancer research and to better protect patients who participate in clinical trials, M. D. Anderson hosted the Ethics and Compliance in Oncology Research conference in April 2008. This first-of-its-kind event focused primarily on cancer research to explore complex issues faced when conducting clinical trials of potential new therapies involving cancer patients. Topics discussed included conducting ethical Phase I studies; issues in oncology research design; clinical trial contracts; conflict-of-interest management; tissue and data repositories; and expanded access programs. “On a national level, we felt it was very important to bring together academics, ethicists, industry sponsors, institutional review board professionals and government regulators to discuss how we can optimize safety for patients in a rapidly changing environment,” says Maurie Markman, M.D., vice president for clinical research, who co-chaired the conference.

Patient Wayfinding — The Fountain

Commitment to the Cancer Care Cycle

Nurse practitioner helps out-of-the-ordinary, high-risk patients by Robin Davidson

Every day spent working in M. D. Anderson’s Cancer Prevention Center reaffirms Robin Coyne’s commitment to prevention. “Prevention and education are so important,” says Coyne, an advanced nurse practitioner. “Encouraging patients to adopt a healthy lifestyle and helping them reduce their risks is very fulfilling.” First and foremost a clinician, Coyne diagnoses and counsels cancer patients, conducts regular surveillance for survivors to help prevent recurrences and works with well patients to prevent cancer altogether. Each Tuesday, she participates in a multidisciplinary group called the Breast Clinical Management Conference. Together, they address difficult cases via a team approach, making decisions on how to monitor and treat breast cases that may be considered out of the ordinary.

breast experts — surgeons, radiologists, pathologists and cancer prevention specialists — watching over their care.” Coyne has developed a database of the hundreds of women presented at the Breast Clinical Management Conference to help identify trends and characteristics of high-risk patients to determine long-term care and prognosis. One day of her workweek is spent seeing patients in the Undiagnosed Breast Clinic.

“The patients’ conditions aren’t benign, but they may not have cancer either. They may just have some abnormal or atypical results that need to be followed closely and cause them to be at high risk for breast cancer. We have a team of

Ritsuko Komaki, M.D., professor in the Department of Radiation Oncology, served as 2007-2008 president of the American Radium Society and received the Marie Sklodowska-Curie Distinguished Award from the Society in Tribute to Maria Sklodowska-Curie.

Robin Coyne

“Naturally, these women are anxious. Either they found an unexplained lump or have received abnormal results,” she says. “I am glad to be their resource, hopefully allaying some of their fears. Educating patients and providing reassurance and compassion are important aspects of overall care. “I’ve worked at M. D. Anderson for 10 years. To see the technology and the resource advances that have taken place in cancer prevention and early detection is so motivating. We’ve made great progress in oncology care. There’s a lot of hope to offer to patients.”

M. D. Anderson Annual Report 2007-2008

New journal focuses on cancer prevention research Scott Lippman, M.D., chair of M. D. Anderson’s Department of Thoracic/Head and Neck Medical Oncology, was appointed founding editor-inchief of Cancer Prevention Research, the newest journal of the American Association for Cancer Research. This monthly journal launched in print in June 2008 and is dedicated to cancer prevention, from preclinical research to clinical trials. “Cancer Prevention Research encompasses the full range of prevention research and opinion in one resource,” Lippman says. “The journal also serves as a forum for commentaries on key public policy issues affecting cancer prevention while highlighting the central role of cancer prevention and early detection in public health.”

Charles Zelbst

How M. D. Anderson’s Tobacco Treatment Program gives A patient hope by Katrina Burton

When Charles Zelbst was diagnosed with bladder cancer in April 2005, his doctor at M. D. Anderson told him he should quit smoking. The recommendation was certainly no surprise to him, but what he did find puzzling was that it was the first time a doctor had ever actually told him this. “Every rational adult knows that smoking is bad for you,” Zelbst says. “But quitting is not an easy thing to do. After 42 years of being an avid smoker, I know that you don’t control the smoking, it controls you.” He began smoking at the innocent age of 10 and was a habitual smoker by 13. He admits his first taste of cigarettes was due mainly to peer pressure, trying to impress a girl. What he didn’t know at the time

was that cigarettes are addictive and would have a lasting effect on his health. As the cravings for the nicotine grew, his habit had him smoking at least four packs of cigarettes a day. At the time of his cancer diagnosis, Zelbst had already tried a variety of cessation methods, from hypnosis to acupuncture, even a 21-day, nosmoking camp, but nothing seemed to rid him of the cravings. It was M. D. Anderson’s Tobacco Treatment Program that finally gave him hope he could kick the habit.

of the State of Texas Tobacco Settlement Funds, offers tobacco-cessation services, including inperson behavioral counseling and several tobacco-cessation medication treatments, at no cost to eligible M. D. Anderson patients. Zelbst, whose cancer is in remission, joined the Tobacco Treatment Program in August 2008 and credits it with giving him some confidence that he will actually quit smoking for good. “The program was the first quitprogram that reduced my cravings,” he says. “Coupled with the medication and counseling, the program is really working for me, and I believe it will work for others.”

The Tobacco Treatment Program, funded by M. D. Anderson’s portion

Commitment to the Cancer Care Cycle

Momentum in Risk Assessment and Early Detection Gaining ground with tools and tests

Epidemiologists, pathologists and oncologists at M. D. Anderson are making great strides in discovering the role of genetics, environment, exercise and diet in the various types and rates of cancer that occur in different groups around the world. They continue to increase the number of risk assessment tools and predictive tests for early detection.

Lung — First-ever risk model for African-Americans

Lung — Mouth may predict lung damage

Researchers created and validated a risk model on the predictability of lung cancer for the AfricanAmerican population. “AfricanAmericans have similar risk factors for lung cancer as Caucasians, but their risks tend to be higher, and there’s a stronger association with occupational exposures, such as wood dust and asbestos, than we have previously observed for whites,” says Carol Etzel, Ph.D., lead author and assistant professor in the Department of Epidemiology. “Additionally, we determined the risks associated with chronic obstructive pulmonary disease (COPD) are substantially higher than those noted in Caucasian subjects.” COPDs, such as emphysema, raise a person’s risk for lung cancer.

For the first time, researchers have evidence that the easily accessible tissue in the mouth can be used to monitor molecular damage in the less accessible tissue of the lungs.

Published in the September 2008 edition of Cancer Prevention Research.

“Our study opens the door to enhancing our ability to predict who has a higher probability of getting tobacco-related cancers. Not only lung cancer, but pancreatic, bladder and head and neck cancers, which also are associated with tobacco use,” says senior researcher Li Mao, M.D., professor in the Department of Thoracic/Head and Neck Medical Oncology. Reported in April 2008 at the annual meeting of the American Association for Cancer Research.

Lung — Discovery narrows field of genetic variations from 317,498 to two Two commonly inherited genetic variations have been found to influence the risk for developing lung cancer. Called single-nucleotide polymorphisms (SNPs), they are places in the human genome that vary by a single DNA chemical building block, or nucleotide. People who have ever smoked and who have one or two copies of either of the SNPs with genetic variation have a greater risk — increased by 28 percent to 81 percent — of developing lung cancer. “The major risk factor for developing lung cancer is cigarette smoking. But what we don’t understand is why some long-term smokers develop lung cancer and others don’t. There are so many different cancer-causing compounds in tobacco smoke that it’s hard to separate them, and we don’t fully understand the mechanisms that result in lung cancer,” says lead author Chris Amos, Ph.D., professor in the Department of Epidemiology. The M. D. Anderson investigators identified variations in genes that made them respond abnormally to nicotine, suggesting that nicotine itself may play a direct role in lung cancer development. These findings put researchers one step closer to understanding lung cancer. Published in the April 2, 2008, edition of Nature Genetics.

M. D. Anderson Annual Report 2007-2008

Breast — Better guidelines for women over 80 Routine mammography may significantly reduce the risk of women over the age of 80 being diagnosed with advanced stage breast cancer. Yet only about one-fifth of these women — who comprise approximately 17 percent of breast cancers diagnosed — have routine mammograms. “Finding breast cancer early in this age group lets us provide patients with less invasive treatment, sparing them from the more toxic therapies given to women diagnosed with advanced disease,” says senior author Gildy Babiera, M.D., associate professor in the Department of Surgical Oncology. Published in the April 21, 2008, edition of the Journal of Clinical Oncology.

Myelodysplastic syndrome — Watching the score A new scoring system identifies patients with MDS, who may appear to have low risk for progression of disease but actually have poor prospects of survival when the disease does progress. “Identifying these low-risk, poor-prognosis patients could allow us to use more aggressive medication at an earlier stage when it may be more effective,” says Guillermo Garcia-Manero, M.D., lead author and associate professor in the Department of Leukemia. Reported in the March 2008 edition of the journal Leukemia.

Bladder — Telltale gene A simple, noninvasive way to detect bladder cancer may be to count copies of a specific gene, Aurora kinase A, in cells gathered from a urine sample. When the gene is overexpressed in urothelial cells, errors occur during cell division, creating either too few or too many chromosomes, instead of the normal pairs of 23.

“Abnormal chromosome counts are the most fundamental feature — the signature — of human cancers. As a biomarker, Aurora kinase A can enable early detection of bladder cancer in voided urine with high degrees of sensitivity and specificity,” says senior author Bogdan Czerniak, M.D., Ph.D., professor in the Department of Pathology.

Infection control — Beyond vascular catheters An antiseptic dye combination developed by M. D. Anderson investigators and already proven effective as a coating for medical devices, such as vascular catheters and other implants, has been shown to be useful in preventing the adherence of bacteria and fungi to medical gloves. In addition, anti-infective urinary catheters coated with these antiseptic dyes were found superior to other U.S. Food and Drug Administrationapproved antimicrobial urinary catheters in both in vitro and rabbit models. Reported at the 2008 annual meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy/ Infectious Disease Society of America.

Published in the Oct. 1, 2008, edition of the Journal of the National Cancer Institute.

Commitment to the Cancer Care Cycle

Momentum in Patient Care and Safety

When it comes to patient care and safety, M. D. Anderson takes a multidisciplinary approach — from considering the ethical and compliance issues of clinical trials to encouraging nurses to identify and correct potential patient safety errors; from careful consideration of who most benefits from critical care to innovative discoveries for infection control.

Nurse’s dissertation provides scaffolding for symptom management by Julie Penne

As an advanced practice nurse in the Department of Cardiology, Anecita Fadol, Ph.D., considers herself a bridge, caring for patients who are diagnosed with both cancer and heart disease. But as a nurse researcher, she also is a bridge builder, having helped design the first symptom assessment tool that provides a stronger scaffolding for decision making in the prevention and treatment of heart failure in cancer patients. Fadol’s tool, which originated as the topic of her doctoral dissertation, is being adapted for study with an interactive telephone response system so patients can directly, frequently and conveniently report their experiences with the most common symptoms of cancer and heart failure. The automated system will phone about 144 study patients every other day, prompting them to gauge their experiences with fatigue, nausea, shortness of breath, numbness or tingling, pain, drowsiness and other symptoms. In addition, the survey asks questions regarding conditions related directly to heart failure, such as ankle swelling, palpitations, nighttime cough and weight gain. With each prompt, patients rate

their recent experience by pressing their telephone keypad from home. Though the survey is automated, Fadol says it is only the day-to-day data that is gathered through electronic means. If a patient presses a number for a symptom that

Anecita Fadol, Ph.D.

surpasses a set threshold, a cardiology nurse is alerted for immediate personal followup. “When the system alerts us about a patient’s response, we call those patients immediately and provide not just a clinical consultation, but also the comfort they often need,” says Fadol. “With this followup call, we can make a more accurate determination of how to best care for patients, whether bringing them to the Emergency Center or monitoring them at home.”

M. D. Anderson Annual Report 2007-2008

Critical care medicine — Automated tools help understand who should receive intensive care M. D. Anderson researchers have created and validated an automated tool that could help evaluate the severity of patients’ illnesses in the intensive care unit and determine which ones will benefit from continued intensive care. To accomplish this, they have modified the Sequential Organ Failure Assessment (SOFA), which is a good indicator of the severity of illness in the critically ill and shows a significant correlation with mortality. The modified SOFA score performs satisfactorily, can be calculated electronically at the bedside of the patient and has the potential to save time and resources. “This and similar scores could be used outside the intensive care environment and in particular for critical care outreach programs such as rapid response teams (RRT). Smart alerts generated by the scores could be used to trigger a visit by an RRT or to call the responsible physician,” says Joseph Nates, M.D., lead author and professor in the Department of Critical Care. Reported in the December 2007 supplement to Critical Care Medicine.

Commitment to the Cancer Care Cycle

Momentum in Pediatric and Young Adult Care

Original research continues to flourish as M. D. Anderson’s pediatric and young adult program grows in size and stature with the establishment of the Children’s Cancer Hospital. A new program also seeks to involve the whole family in every aspect of care. Osteosarcoma, certain leukemias and neuroblastoma — Marrying two therapies creates kinder treatment

Leukemia — Novel process could improve immune therapy Researchers have found a new way to keep natural killer “NK” cells active, while increasing their number from umbilical cord blood, then using them to kill human leukemia cells in mice. “Cord blood is a promising source of natural killer cells because these cells have enhanced sensitivity to stimulation and decreased potential to cause graft-versus-host disease, and they are available off-the-shelf from cord banks throughout the world,” says Patrick Zweidler-McKay, M.D., Ph.D., assistant professor in the Division of Pediatrics, about work performed with Elizabeth Shpall, M.D., professor in the Department of Stem Cell Transplantation. Reported at the May 2008 annual meeting of the American Society of Pediatric Hematology/Oncology.

A combination therapy has the potential to treat several types of childhood cancer without adding much toxicity. “Traditional chemotherapy kills fast-growing cells like cancer, but also kills healthy, fast-growing cells, like hair, bone marrow and mucous membranes, making the drugs very toxic,” says Dean Lee, M.D., Ph.D., assistant professor in the Division of Pediatrics in the Children’s Cancer Hospital. “A newer class of epigenetic drugs, called histone deacetylase inhibitors, affects gene expression in a cell without directly affecting the gene itself. We found that some of these drugs can make cancer cells more recognizable and vulnerable to natural killer cells. Combining these drugs with administration of natural killer cells from a donor could be used in patients who can’t tolerate more toxic therapies.” Reported at the May 2008 annual meeting of the American Society of Pediatric Hematology/Oncology.

Proton therapy — Child-centered approach calms young fears M. D. Anderson’s Proton Therapy Center is the only one in the country to treat children of all ages. Because the precision of the therapy requires them to remain perfectly still, children younger than 8 years old are sedated. To ease their fears and anxieties during the treatments, Vivian Porche, M.D., head of the PTC anesthesia service, and Cynthia Williams, the lead nurse anesthetist and coordinator of the service, have devised a program that includes making sure parents and their children feel as comfortable and secure as safely possible. This approach includes pre-treatment meetings, hanging toys from the gantry, singing their favorite songs and even letting children push the buttons to start the anesthesia. The hopes are that the proton therapy — a pencil-thin beam of radiation that accurately targets a specific area, causing little damage to adjacent normal tissue — will provide the children a better quality of life with fewer side effects as they age.

M. D. Anderson nurses make good catches Through its Good Catch Program, the Division of Nursing encourages inpatient unit nurses to report potential patient safety errors that they identify and correct as part of their daily practice. Reporting such instances allows for analysis of systems and factors that may contribute to errors. The program — which is becoming a national model for development of similar systems — shifts emphasis from the negative implication of “near miss” or “close call” to focus positively on nurses’ actions to identify and prevent potential errors with medications, equipment and patient care. “We’re trying to create a fair and supportive culture in which nursing staff feel empowered to identify opportunities to improve patient safety and eliminate any fear of reporting,” says Barbara Summers, Ph.D., vice president and chief nursing officer.

M. D. Anderson Annual Report 2007-2008

Caring for patients, caring for families by Gail Goodwin

Patty Wells, director of family-centered care in the Children’s Cancer Hospital at M. D. Anderson, is a pediatric nurse who has become an expert in the field. “Family-centered providers acknowledge that involving families in hospital planning, evaluation and policymaking improves children’s care and that best practices are shaped by families and professionals working together,” Wells says.

the first Family Advisory Council and Patient Advisory Council at Cincinnati Children’s Hospital Medical Center. She discovered that family-centered care was a philosophy and practice she believed in.

It takes collaboration beyond the clinical level and creates advisory roles for patients and families.

At M. D. Anderson, she is helping incorporate family-centered care into the operations of the Children’s Cancer Hospital from the ground up. “It’s a lot of common sense and a lot of work that will require the efforts of everyone, but the payoff will be an improved patient and family experience that is safe and more efficient and energized,” she says.

Wells has been a nurse and administrator in several medical facilities and has always focused on pediatrics. Before coming to M. D. Anderson, she established the Family Resource Center and then

“Faculty and staff here are working past a fear of transparency and are turning patients and their families into partners who contribute to their own health care. “We have a long way to go,” she adds. “We must incorporate the family-centered care language into all job descriptions, continue to educate everyone and celebrate and market what we have already accomplished. Family-centered care actually means including patients and families in every aspect of the medical experience, from bedside to policy making and everywhere in between.” Family needs are consistent, Wells has discovered, but their experiences and perceptions are very different. “It’s my hope that as we move forward with family-centered care, everyone will discover that this is a win-win proposition for patients, families and everyone working at the Children’s Cancer Hospital.”

Patty Wells

Commitment to the Cancer Care Cycle

Momentum in Survivorship

Realizing the growing importance of survivorship issues as cancer patients survive their disease or live longer with chronic disease, M. D. Anderson has been carefully studying how to best serve this growing population. Today, two-thirds of cancer patients can expect to live five years or longer. With more than 11 million survivors in the United States and an estimated 22.4 million worldwide, the institution has established a Department of Survivorship, is initiating pilot survivorship programs in three clinics and has designed a multidisciplinary model of survivorship care.

Pediatric survivor builds his own history by Gail Goodwin

In his own words, Andrew Pegoda is self-instructed, selfdirected and family-guided, with research as his focus and fascination. “I appreciate that the study of history touches on sociology, psychology and literature. It’s a perfect fit for me,” says Pegoda, who has a passion for teaching the subject. From those qualities, his college classes at Brazosport College, the University of Houston and, now, the University of Houston at Clear Lake are a natural progression, and he’s been helped along the way with scholarship grants from the Children’s Art Project at M. D. Anderson.

affected the nerve to his vocal cords and prevented him from speaking for several months. He also has had vision issues, as well as an absence of a growth hormone for which he still takes testosterone daily. Though only 22 years old, Pegoda has grown up more quickly because of his medical experience. His father

However, Pegoda’s medical education began when he was 4 years old with a non-malignant brain tumor and a diagnosis of neurofibromatosis. In subsequent years, he developed a tumor on his diaphragm, which

Waun Ki Hong, M.D., head of the Division of Cancer Medicine, was appointed to a six-year term on the National Cancer Advisory Board by former President George W. Bush.

Andrew Pegoda

describes him as “wiser than his years” and proudly touts his son’s achievements of winning a distinguished student award at Brazosport and now editing a college textbook. Pegoda continues maintenance treatment at M. D. Anderson while in the doctoral program at the University of Houston studying, of course, history. It won’t be long before it’s Professor Pegoda who is at the head of the class teaching his students that history can be fun and exciting.

M. D. Anderson Annual Report 2007-2008

Physician helps patients, institution navigate the ‘new normal’ by Mary Brolley

After 22 years at her “one and only” job, Alma Rodriguez is an expert in lymphomas and, even more important, in lymphoma patients. Rodriguez, M.D., vice president for medical affairs, has watched, listened and tended to these patients, whose diseases, because of medical advances, may have been cured or become chronic, treatable conditions. Now, her background in helping these long-term patients makes her a perfect choice to lead the institution’s survivorship initiative.

‘new normal,’ monitor their health, get them psychosocial counseling, find out what their concerns are.” Patients worry about recurrences — and the risk of latent effects from often-harsh treatments. Some patients wish to return to primary care doctors in their own communities, while others choose to stay with their M. D. Anderson physicians.

To meet these needs, Rodriguez envisions survivorship clinics in each cancer specialty — gathering places where patients can have their health monitored, take classes, get counseling or join a support group. In fact, survivorship clinics are being piloted in three clinics at M. D. Anderson. The journey has just begun, Rodriguez says. “We must educate patients and providers — and continue research on how cancer treatment affects patients’ health in the future.”

“Twenty years ago, oncologists didn’t have a good sense of how to help adults who lived many years with cancer,” she says. “But because I’ve cared for many of my patients for so long, I became very interested in survivorship.” As the institution addresses the challenges of this emerging field, Rodriguez knows a great deal about how to prepare patients for life after diagnosis and treatment. She knows that after treatment ends, many patients feel relieved, but also drained and exhausted. “Cancer diagnosis and treatment are life-changing,” she says. “We need to help patients navigate through their

Alma Rodriguez, M.D.

Commitment to the Cancer Care Cycle

Survivor helps break down the walls of silence by Mary Brolley

Although she worked daily with African-American cancer survivors, senior behavioral research coordinator Pamela Lewis didn’t fully understand what they were going through. For one thing, she couldn’t fathom why so many African-American women seemed unwilling or afraid to be screened for breast cancer, despite the deadly swath the disease is carving through their communities. There is a curious — and dangerous — silence around cancer diagnosis and treatment, Lewis felt. But when a baseline mammogram at age 36 revealed that she, too, had the disease, she began to understand. “I didn’t want to tell anyone what I was going through,” she says. “There was a stigma in my community about having breast cancer.”

diagnoses. She serves on its steering committee and will chair the organization’s Living With, Through and Beyond Cancer Conference next fall.

Lewis also is senior coordinator of Tendrils, an interactive computerized educational tool to help female cancer survivors improve their sex lives.

In addition, Lewis feels a strong responsibility to reach out to patients and survivors in underserved communities through what she calls “emergency case management.” She is constantly linking survivors and families to oncology resources in their communities to help them deal with the financial and insurance barriers to quality treatment.

And she volunteers with Anderson Network, a patient/caregiver support organization and program of the Department of Volunteer Services that matches newly diagnosed patients to survivors with similar

Surviving cancer has been a complicated process for Lewis. “I’m a work in progress. I have fears, sure. I faced the threat of dying young. But I am thankful to be alive. I need to give back to those who really need me.”

“Before I had cancer, there was a wall between me and them,” she says. “Maybe being a survivor makes me more credible.”

Three years after treatment, Lewis is thoroughly engaged in her work at M. D. Anderson, coordinating psychosocial studies for Leslie Schover, Ph.D., professor in the Department of Behavioral Science. Her cancer experience allows Lewis to connect with clients more easily than before.

Pamela Lewis

Joint Commission survey a success Continuing a long tradition of focusing on safe, comprehensive care for patients, M. D. Anderson again received accreditation from the Joint Commission, following a five-day visit by a team of surveyors. Since 1951, M. D. Anderson has been consistently accredited by this independent, not-for-profit organization that accredits and certifies more than 15,000 health care institutions and programs in the United States. Held every three years, the survey includes close observation of a range of quality, safety, patient care and support practices.

M. D. Anderson Annual Report 2007-2008

Multidisciplinary model of survivorship

Prevention

Psychosocial Support/ Symptom Management

TIER 1

Internal Medicine

Patients with low risk of complications or relapse = surgery

TIER 2

Oncology

Patients with complications/risk of treatment or second malignancies = chemotherapy, radiation therapy

TIER 3

Patients with high risk of relapse; active slow growing/controlled disease; intensive chemotherapy/radiation/stem cell transplantation with a high risk of side eﬀects = SCT, chronic and high-risk cancers

M. D. Anderson health care providers have designed a model of survivorship to help anticipate needs and provide the care that those living with and beyond cancer may require. The course of care is defined by the four categories above. Depending on the treatments they received and the potential side effects, survivors generally fit into one of the three tiers.

Citywide event pays tribute to spirit of survivors

Defining what survivors need and when

Internet site provides in-depth information

The Survivorship Houston Coalition, led by M. D. Anderson, held its first Cancer Survivors’ Day June 1, 2008. The citywide celebration, held at the Houston Texans training center at Reliant Park, was open to all Houston-area cancer patients and their families, regardless of where or when they were treated. More than 500 participants attended the event, which included a variety of speakers, entertainment and activities for children. The goal was to recognize and celebrate the progress made in cancer treatment and the lives of Houston-area survivors, as a result of cancer research.

Based on a literature review of long-term and late effects related to cancer and cancer treatments, M. D. Anderson’s Cancer Survivorship Program has developed algorithms of care and criteria for transitioning patients to survivorship as a distinct phase of cancer care. Surveillance, risk reduction and early detection for recurrence or second cancers, monitoring for late effects and emphasis on quality of life are the four domains identified in these new practice guidelines.

Available at www.mdanderson.org/ topics/survivorship, M. D. Anderson’s Internet site offers information for cancer patients at every stage of survivorship. It also provides links to the many programs and services available to survivors as they live with, through and beyond cancer. In addition, patients can request a myMDAnderson.org site from their treatment centers for personalized survivorship information and care.

Commitment to the Cancer Care Cycle

Momentum in Symptom Management and Supportive Care Helping patients at all levels of care

Improving quality of life by preventing or treating symptoms of cancer, side effects of treatment and the psychological and social issues that result from either is the aim of M. D. Anderson’s Supportive Care Center. Physicians in the center offer a mobile team for inpatients, while also staffing a Palliative Care Acute Inpatient Unit. Patients referred to this unit are considering or transitioning from disease-modifying treatment to end-of-life care. A $2.5 million grant from The Brown Foundation Inc. supports an array of research projects, programs and facilities.

Lymphedema — Education key to better health

Fatigue — A step toward better definition

Lymphedema is an accumulation of excess fluids that causes swelling in the arm after lymph nodes are removed. Quick action by professionals can lead to a decrease in its incidence as well as better management of chronic lymphedema and improved quality of life for breast cancer patients.

A study at M. D. Anderson identified three primary themes around fatigue: loss of strength or energy (tiredness, weakness), major effects of fatigue (lack of motivation, inability to perform usual activities) and associated sensations (malaise, aching, lack of appetite) among patients treated with standard radiation therapy.

“Women are living longer as breast cancer treatments get better, but at the same time, they face more devastating side effects, like lymphedema.

“While fatigue is a well-recognized symptom of cancer and its treatment, the measurement of fatigue has been based on many different ideas and definitions, few of which have included patient input. We’re trying to define fatigue better, based on the patient’s perceived experience. Once we determine the critical elements of fatigue, we’ll be better equipped to ask the right questions of patients. Health care professionals, including nurses, will be in a much better position to intervene with patients to manage or prevent fatigue,” says Loretta Williams, Ph.D., an instructor in the Department of Symptom Research.

“This research centers on what is important to patients and their quality of life after treatment. Nurses are on the frontline and may hold the key to proactively preventing lymphedema in many patients by educating them about triggers and symptoms, providing continual and specific lymphedema assessments during each visit and pursuing research in this area,” says Mattie McDowell, clinical patient safety specialist in the Department of Performance Improvement. Reported in May 2008 at the 33rd Annual Congress of the Oncology Nursing Society.

Reported in May 2008 at the 33rd Annual Congress of the Oncology Nursing Society.

Thomas W. Burke, M.D., executive vice president and physician-in-chief, was elected the 40th president of the Society of Gynecologic Oncologists.

Origami Crane for Healing

Metastatic brain tumors — Study prompts change in standard practice Cancer patients who receive stereotactic radiosurgery (SRS) and whole brain radiation therapy for the treatment of metastatic brain tumors run more than twice the risk of developing learning and memory problems than those treated with SRS alone. “This is a case where the risks of learning dysfunction outweigh the benefits of disease control and tip the scales in favor of using SRS alone. Patients are spared from the side effects of whole brain radiation and we can preserve their memory and learning ability to a higher degree. Here the study suggests patients who receive SRS as their initial treatment and then are monitored closely for any recurrence will fare better,” says Eric Chang, M.D., associate professor in the Department of Radiation Oncology. Reported in October 2008 at the 50th annual meeting of the American Society for Therapeutic Radiology and Oncology.

M. D. Anderson Annual Report 2007-2008

Physician in sync with patients’ special needs by Erika Hargrove

Many who have cancer stay braced for bad news. As the disease progresses, so do their preparations to hear the worst. Being prepared doesn’t make it any easier, but how they hear such news can make a big difference. The concept is simple enough, but until recently there hasn’t been any evidence to back up the belief.Thanks to Eduardo Bruera, M.D., chair of the Department of Palliative Care and Rehabilitation Medicine, more insight is available. He and his colleagues studied patients’ perceptions and preferences around a physician’s posture when delivering bad news.

The study found that 168 patients with advanced cancer perceived physicians who sat while delivering bad news as significantly more compassionate and concerned than those who stood. “It’s sort of common knowledge in the profession — just something physicians are taught early on — to sit when you deliver bad news,” Bruera says. “But there had never

been any evidence to support the fact that this practice really made a difference to patients. This is why we decided to do the study.” Bruera admits that space in exam rooms is often limited, and, therefore, it’s not always possible for physicians to sit. However, this study, published in the Journal of Palliative Medicine, will help physicians and other medical professionals become more aware of their postures when they are in this unfortunate situation. Studies such as this and others have made Bruera a leader and respected mentor in palliative care. Suresh Reddy, M.D., associate professor in the Department of Palliative Care and Rehabilitation Medicine, says the department is positioned for growth and progress due to Bruera’s visionary leadership. “Dr. Bruera walks, talks and sleeps evidencebased palliative care,” Reddy says. “He inspires a team, challenges the processes, enables others to act and gives candid feedback. He has crystal clear concepts about various principles in life.”

Eduardo Bruera, M.D.

Commitment to Research

basic science

Commitment to Research

translational research

targeted cancer therapy

M. D. Anderson Annual Report 2007-2008

clinical trials and new treatments

With a faculty that includes more than 1,400 scientists and clinicians, M. D. Anderson is able to move discoveries from the laboratory to patients where they can be assessed in clinical trials. These advances are aided by our knowledge of the human genome and the mechanisms that regulate gene expression, as well as by advances in technology and a greater understanding of the impact of behavioral and environmental factors.

Commitment to Research

Among biostatisticians, Jeffrey Morris is a rock star. Biostatistician makes waves

by Mary Brolley

M. D. Anderson Annual Report 2007-2008

JeffRey Morris, Ph.D.

His creation of a novel statistical method to capture and interpret biological data has made researchers all over the world take note. In 2003, Morris, Ph.D., associate professor in the Department of Biostatistics and Applied Mathematics, wrote a scientific paper explaining how a wavelet-based statistical modeling method had yielded biological insights into colon carcinogenesis, the process by which normal cells are transformed into cancer cells. The paper won his research group two major awards. And soon after its publication, Morris started hearing from researchers in many countries who were eager to adapt his method to their research.

The primary focus of Morris’ methodological research involves developing statistical methods for analyzing functional and image data, and for evaluating various types of data encountered in bioinformatics. These new models have helped users of the latest high-throughput technologies — those that can analyze or produce information at a high rate of speed — extract more information from their data. In addition, he collaborates with researchers at M. D. Anderson on various research projects, most involving gastrointestinal cancers. Besides designing studies and analyzing data,

he tries to help them see other questions that can be addressed by the data they have collected. Named an M. D. Anderson Faculty Scholar in 2004, Morris also received the Gottfried E. NoetherYoung Scholar Award from the American Statistical Association in 2005. And he is still “tweaking and expanding” the methods he has developed — for example, to handle image data — as researchers around the world continue to ask for his help. “I’m always thinking about ways to make it flexible enough for many applications and accessible to as many users as possible. I want my research to have an impact,” he says, then pauses. “I’m confident that it’ll have a long-term impact.”

Commitment to Research

Momentum in Basic Science and Translational Research Detecting mechanisms and markers

New research approaches at M. D. Anderson focus on the human genome and the regulation of gene expression. Scientists identify and study particular genes and proteins that play a role in tumor growth or suppression, and they investigate the molecular mechanisms that account for the effects of these abnormal genes and their products. They collaborate in developing new targeted therapies to counteract the growth and survival of cancer cells, and they find ways to starve them of a blood supply and growth-promoting factors. They also investigate how to elicit immune responses to ward off and destroy cancer cells, and they use diagnostic imaging to determine abnormal molecules and activities in the cancer. The aim in each case is to translate that research to the patient.

p53 presents a different face New data show that restoring the function of the cell’s p53 gene, inactivated in many types of cancer, could just as easily express a mutant version of the protein, causing cancer cells to thrive and spread rather than die. Until this finding, reactivation of p53 was thought to have great therapeutic potential. While this may still be true, the gene is more complex than originally thought. “As we develop therapies to restore the function of p53, we need to make sure we first know what version of this gene is present in a patient’s tumor and then decide how to treat it,” says senior author Guillermina Lozano, Ph.D., chair of the Department of Genetics. Reported in the May 2008 issue of the journal Genes and Development.

‘The three musketeers of cancer’ ambush a tumor suppressor New research illuminates a mechanism of attack by at least one of three cancer-causing proteins on FOXO3a, a member of a family of special tumorsuppressing proteins. “We know that FOXO3a is inactivated in about 80 percent of breast tumors, and that it’s likely to be inactivated in other solid tumors because each of these three major pathways that promote the formation and development of cancer target it. The implication is that activation of this protein (FOXO3a) would be a great therapeutic benefit because it would reintroduce a powerful tumor suppressor,” says Mien-Chie Hung, Ph.D., chair of the Department of Molecular and Cellular Oncology. Reported in the Feb. 10, 2008, issue of Nature Cell Biology.

Enzyme active in drug resistance and metastasis Overexpression of an enzyme — tissue type transglutaminase (TG2) — in ovarian cancer is associated with increased tumor cell growth and adhesion, resistance to chemotherapy and lower overall survival rates. When researchers targeted and silenced TG2 in animal models, cancer progression was reversed, suggesting TG2 also may provide a novel therapeutic approach for late-stage ovarian cancer.

“TG2 appears to fuel different types of cancer through multiple molecular pathways, making it an important therapeutic target,” says Kapil Mehta, Ph.D., lead author and professor in the Department of Experimental Therapeutics. His lab also has connected TG2 overexpression to drug-resistant and metastatic melanoma, breast cancer and pancreatic cancer.

Rhonda Jacob, D.D.S., professor in the Department of Head and Neck Surgery, served as the 90th — and first woman — president of the Academy of Prosthodontics.

Reported in the July 15, 2008, issue of Cancer Research.

M. D. Anderson Annual Report 2007-2008

Renowned leader for Bioinformatics, Computational Biology Scholar, investigator and inventor John Weinstein, M.D., Ph.D., joined M. D. Anderson in January 2008 as chair of the Department of Bioinformatics and Computational Biology, part of the Division of Quantitative Sciences, which plays a growing role in supporting the institution’s research institutes and extending

John Weinstein, M.D., PH.D.

its research mission. Among Weinstein’s accomplishments,

Pulmonary Aerosol tackles deadly infections An inhaled stimulant launches an immune system response in the lining fluids in the lung, which kills invading pathogens on contact — protecting mice against lethal pneumococcal pneumonia and other deadly bacterial, viral and fungal infections of the lungs. “We study airway inflammation, and we often think about that in a negative context, how to stop inflammation, as in the allergic inflammation that causes asthma. But surely the ability of airways to become inflamed is there for a good reason. So we asked: Can we set off a type of inflammation that strengthens protection against infection? The answer is, ‘Yes,’” says Burton Dickey, M.D., senior author and chair of the Department of Pulmonary Medicine. Reported at annual meeting of the American Society for Cell Biology in December 2007.

he has invented a novel, patented method for measuring gene expression; developed the “Miner Suite” of widely used bioinformatic computer resources; and was cited as a pioneer of postgenomic biology, earning him a nomination for the National Medal of Technology in 2004. His 260 publications

Connecting diet and cancer pathways A restricted-calorie diet inhibited the development of precancerous growths in a skin cancer model, reducing the activation of two signaling pathways known to contribute to cancer growth and development. By contrast, an obesityinducing diet activated those pathways, leading to cancer cell proliferation and survival. “These results, while tested in a mouse model for skin cancer, are broadly applicable to epithelial cancers (which comprise 80 percent of all cancers) in other tissues,” says John DiGiovanni, Ph.D., chair of the Department of Carcinogenesis and director of the Science Park-Research Division in Smithville, Texas. Reported at the April 2008 annual meeting of the American Association for Cancer Research.

Immunology — A unique combination ignites immune response usually aimed at fighting infection A human peptide that acts as a natural antibiotic against invading microbes also can bind to the body’s DNA and trigger an immune response. This response is a likely key driver of autoimmune disease. It also is an integral part of an early warning system that flags tissue damage to launch a protective inflammatory response after an injury occurs. “Follow-up research is under way to better understand this pathway and to exploit it to treat both autoimmune disease and cancer,” says Michel Gilliet, M.D., senior author and associate professor in the Department of Immunology.

include 11 as first author in the journal Science. Bioinformatics and Computational Biology conducts collaborative research with clinical and basic science departments, and supports the need for quantitative sciences in the fields of genomics, proteomics, radiation therapy, molecular and cell biology, and computer-assisted diagnoses and image analysis.

Reported in the October 2007 edition of Nature.

Commitment to Research

Patience and curiosity lead young researcher to breakthrough discovery by Sandi Stromberg

Growing up in a small village in South India, Sendurai Mani had an insatiable curiosity. From his grandmother, he learned about local medicinal plants. Then, while working on his master’s degree at Madurai Kamaraj University in Madurai, India, he remembered one plant whose extract was deadly. His hunch to work with his professor, patiently testing it for anti-cancer activity, led to his first exciting discovery and set him on his path toward a Ph.D. at the Indian Institute of Science in Bangalore, India. It was there in 1998 that he met Robert Weinberg, Ph.D., a founding member of the Whitehead Institute and professor at Massachusetts Institute of Technology. Weinberg invited him to join his lab and to choose an area of study. Mani chose metastasis.

With a colleague, he set out to answer the question: What makes a non-metastatic, square and stuck cancer cell become a spindly, mobile and metastatic one. After years of patient and collaborative work, they found that by switching on any one of three genes — called Twist, Snail and FOXC2 — they could force cancer cells in a petri dish to undergo the square-to-spindly shift, making them far more capable of initiating new tumors. When Mani took this one step further by using healthy cells, he found the cells appeared to take on properties of stem cells, including the ability to make

“The first lesson I learned in that lab was the importance of collaboration, that team efforts allow research to advance more quickly,” says Mani, assistant professor in the Department of Molecular Pathology.

John Mendelsohn, M.D., president and professor in the Division of Cancer Medicine, received the 2008 Dorothy P. Landon–AACR Prize for Translational Cancer Research for his pioneering work that led to the discovery of a new class of cancer treatment agents and greatly expanded knowledge of targeted therapies.

Sendurai Mani, PH.D.

vast numbers of copies of themselves. On the basis of this breakthrough discovery and his novel strategy for using an innovative lineage-tracing mouse model, the Jimmy V Foundation recently named him a V-Scholar. This two-year award recognizes talented young cancer researchers, enabling them to quickly establish their laboratories and gain a competitive edge. Mani hopes that his future research will help scientists understand the biology of cancer metastasis and ultimately lead to the development of interventions to target and destroy cells with metastatic potential that cause cancer to spread and lead to

M. D. Anderson Annual Report 2007-2008

New partnerships spur drug development In an effort to bring the latest drugs to patients faster, M. D. Anderson has signed agreements with several pharmaceutical companies. “Strategic alliances are the way of the future where academe and industry work together toward common goals that benefit our patients,” says Robert Bast, M.D., vice president for translational research. •

An agreement with AstraZeneca is helping advance understanding of neuropathic pain caused by cancer chemotherapy, a side effect that often limits optimal therapeutic dosing in cancer treatments. The alliance focuses on identifying neurobiological differences between cancer patients who develop chemotherapyinduced pain and patients who experience little or no pain.

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An agreement with GlaxoSmithKline established a partnership to more effectively develop new therapeutic, diagnostic and imaging products of mutual interest. The alliance concentrates on integrated preclinical and clinical programs for disease intervention, addressing key questions in the lab and translating those findings to the clinic and then back to the lab.

Commitment to Research

Momentum in Clinical Trials and New Treatments Innovative therapies developed through clinical trials — a hallmark of M. D. Anderson

M. D. Anderson is a leader in clinically oriented research for all cancers, including those that are hard to treat. Researchers are spurred by the needs of patients and encouraged by the results of a number of clinical trials with novel new drugs that are being introduced into the clinic here. They also collaborate in large-scale trials that can rapidly enroll the numbers of patients needed for U.S. Food and Drug Administration approval of new drugs. Currently, M. D. Anderson clinical investigators are conducting more than 1,100 therapeutic trials for many types of cancer — across departments, across the nation and internationally.

Inflammatory breast cancer — Funding to move forward

Breast Cancer — drug produces surprise results For metastatic disease

Thyroid Cancer — Blood vessel inhibitor may lead to individualized therapy

M. D. Anderson’s Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, the first such program devoted to the disease, received a $4 million appropriation from the Texas Legislature in October 2007 for research into this rare, aggressive and often lethal type of breast cancer. A recent study led by M. D. Anderson investigators found that combining computed tomography with positron emission tomography enables researchers to more quickly and accurately pinpoint the location of metastases from inflammatory breast cancer.

A clinical trial showed that Iressa®, a drug that has shown less than promising results in the treatment of some cancers, enhances the effectiveness of hormonal therapy for the treatment of specific types of metastatic breast cancers. “These findings show the possibility of adding a targeted therapy, such as Iressa, to improve the benefit from hormonal therapy, giving another option to women with this type of metastatic disease,” says Massimo Cristofanilli, M.D., associate professor in the Department of Breast Medical Oncology.

An experimental drug that inhibits the formation of blood vessels to feed a tumor can slow the growth of metastatic papillary thyroid cancer in some patients. Researchers at 42 institutions in 10 countries and scientists from Amgen, who developed the biologic agent, motesanib, planned and conducted one of the largest clinical trials ever done for this patient population. Further genetic analyses of 25 patients indicated that those with a specific mutation known as BRAF V600E in their tumors had a better response to the investigational drug than those without the mutation.

Published in the March 15, 2008, edition of Clinical Cancer Research.

Leukemia — Strong early results for new frontline therapY Two drugs approved for chronic myelogenous leukemia — dasatinib and nilotinib — are showing promise as frontline therapy for newly diagnosed patients who have received no prior therapy for their disease. Both have been approved by the FDA for patients who no longer tolerate, or whose disease has become resistant to, the frontline therapy Gleevec®. Lead author on the study was Jorge Cortes, M.D., professor in the Department of Leukemia. Reported December 2008 at the 50th annual meeting of the American Society of Hematology.

Reported at the May 2008 annual meeting of the American Society for Clinical Oncology.

Melanoma — biomarker study shows promise Researchers have identified a safe and well-tolerated dosage of a new biologic agent, TK1258, or dovitinib lactate, for the treatment of patients with advanced melanoma. As one of the first drugs to target fibroblast growth factor receptors that bind to members of this family of proteins, the Phase I study is a key trial to examine the clinical importance of FGF receptors in melanoma and other cancer types. Presented by Kevin Kim, M.D., associate professor in the Department of Melanoma Medical Oncology, at the American Society of Clinical Oncology 2008 annual meeting.

“Finding that patients whose tumors bear a particular mutation were more likely to respond to the drug is an example of where we would like to head in our research. This is the first of the various thyroid cancer trials to identify specific mutations that might allow us to individualize therapy,” says lead author Steven I. Sherman, M.D., chair of the Department of Endocrine Neoplasia and Hormonal Disorders. Published in the July 3, 2008, edition of the New England Journal of Medicine.

M. D. Anderson Annual Report 2007-2008

Proton therapy — Collaborative efforts garner important grant Based on previous research with proton therapy, M. D. Anderson and Harvard Medical School/Massachusetts General Hospital received a special program project grant from the National Cancer Institute for a twofold study. First, radiation oncologists will conduct physics research to minimize factors that limit its effectiveness — for example, metal objects, such as dental fillings, prostheses, surgical clips and spinal braces. Second, they hope to improve the understanding of the biological effects of proton therapy and incorporate this knowledge into the design of proton dose distributions as they plan treatments. In addition to tumor shrinkage, these effects can include weight loss and other factors that may require adaptive re-planning during proton therapy. “The clinical trials of early-stage and locally advanced lung cancer offer the hope of improving treatment and outcome, which would positively affect very large numbers of patients. With the grant, we expect to begin addressing important issues at an accelerated rate. Clinical trials within the scope of the grant, in addition to lung, include liver, medulloblastoma, rhabomyosarcoma, spine and paranasal sinus,” says James Cox, M.D., head of the Division of Radiation Oncology.

Multiple myeloma Two pivotal trials in the treatment of this rare and lethal cancer of the bone marrow led to U.S. Food and Drug Administration approvals:

Grant boosts study of inflammatory breast cancer

Combining therapies improves outcome

Collaboration leads to breakthrough

A new grant brings together clinicians,

Results of a Phase III international study comparing the efficacy and safety of the combination of pegylated liposomal doxorubicin (PLD) plus bortezomib with bortezomib alone in patients with relapsed or refractory multiple myeloma led to FDA approval of PLD for this group of patients. Robert Orlowski, M.D., Ph.D., principal investigator and associate professor in the departments of Lymphoma/Myeloma and Experimental Therapeutics, joined M. D. Anderson in September 2007, as the director for the Section of Myeloma.

Results of a Phase III clinical trial led to FDA approval of lenalidomide and dexamethasone for the treatment of relapsed myeloma. In this study, conducted at 44 centers in the United States and Canada, patients who received this thalidomide derivative in combination with the steroid dexamethasone had improved median overall survival time.

Published in the Sept. 1, 2007, edition of the Journal of Clinical Oncology.

“This trial highlights how largescale cooperation in a team effort can quickly confirm benefits and introduce new active agents for patients. We also owe a debt of gratitude to the willing patients who participated in this study,” says Donna Weber, M.D., lead author and associate professor in the Department of Lymphoma/ Myeloma.

surgeons, laboratory investigators, physician scientists and consumer advocate/breast cancer survivors to accelerate advances in detection and improved therapy options for women with inflammatory breast cancer. Fredika Robertson, Ph.D., professor in the Department of Experimental Therapeutics, and Massimo Cristofanilli, M.D., associate professor in the Department of Breast Medical Oncology, are co-principal investigators on the $7.5 million American Airlines Susan G. Komen for the Cure Promise Grant. IBC is a rare but aggressive type of breast cancer that develops rapidly and masquerades as an infection, making the affected breast red, swollen and tender.

Published Nov. 22, 2008, in the New England Journal of Medicine.

Commitment to Research

Dream setting, dream job for researcher by Mary Brolley

Some days, when she looks up from her work to see a deer or a rabbit wandering through her stretch of the piney woods, Karen Vasquez can’t believe her good fortune. Sure, Vasquez, Ph.D., has plenty of responsibilities as associate professor, supervising 11 researchers intent on finding new targets for cures for cancer. But following her calling in such an idyllic setting — the Department of Carcinogenesis at M. D. Anderson’s Science Park- Research Division near Smithville, Texas — is a dream come true for Vasquez. She first visited the Smithville facility as a graduate student, attending a Lost Pines Molecular Biology Conference, and thought, “How could anyone be lucky enough to actually work here?”

Vasquez and her team recently found that a protein called HMGB1, previously thought to block DNA repair, actually enhances such repair. An abundant chromosomal protein, HMGB1 has long been known to bind sites of damaged DNA, and recent evidence suggests that it is involved in pro-inflammatory processes. Several new drugs under development target the protein, in hopes of reducing the pathogenic inflammation that occurs

In her graduate research, Vasquez “became fascinated with DNA structure and the mechanisms of DNA repair,” especially as they affect carcinogenesis. Today, she and her team specialize in DNA structure-induced genetic instability. “We take our best, most educated guess to the bench, analyze our findings, then design the next move. It’s like solving a puzzle.”

Raymond N. DuBois, M.D., Ph.D., provost and executive vice president, became the fifth M. D. Anderson faculty leader to serve as president of the American Association for Cancer Research.

Karen Vasquez, PH.D.

in such conditions as rheumatoid arthritis and sepsis, or blood poisoning. “However, therapy for arthritis is longterm,” she says, “and our findings suggest that depleting this protein could potentially leave patients more vulnerable to developing cancer.” Vazquez knows that doing the work she loves — solving the puzzles — in a lovely and peaceful setting is quite a perk.

M. D. Anderson Annual Report 2007-2008

New building expands research opportunities M. D. Anderson celebrated the 2008 groundbreaking for a 23,000-square-foot, $16 million building to accommodate growth of research programs and shared resource facilities at the Virginia Harris Cockrell Cancer Research Center campus near Smithville, Texas. Due to be completed by spring 2009, it will expand the Department of Carcinogenesis and the Center for Research on Environmental Health Sciences, funded by the National Institute of Environmental Health Sciences. Research programs on this campus are highly interactive and focused on cancer cause and prevention. Researchers are studying biochemical, cellular and molecular mechanisms of carcinogenesis, the process by which normal cells are transformed into cancer cells. New discoveries about the interplay between environmental factors and genetic factors in cancer development are emerging from these studies.

Commitment to Research

Momentum in Targeted Cancer Therapy Making an indelible mark

As researchers learn more about genes, proteins and their inherited or acquired abnormalities, they are increasingly able to design therapies specifically targeted to an individual’s genetic make-up. Personalized treatments will allow physicians to provide the safest and most effective therapies to their patients with the best outcomes. M. D. Anderson’s commitment to research in this area will be enhanced by expanded facilities. In June 2008, construction began on the Center for Targeted Therapy, part of the multi-center Red and Charline McCombs Institute for the Early Detection and Treatment of Cancer. “By building this facility and filling it with the brightest minds, the best equipment and the spirit of innovation, we expect to make an indelible mark on the emerging field of personalized medicine,” says John Mendelsohn, M.D., president of M. D. Anderson. It’s scheduled for occupancy by 2011. The center will be home to the Translational Chemistry Service, siRNA Screening Service, Molecular Modeling Service and Non-Coding RNA Program — all available to help investigators at M. D. Anderson with their research endeavors.

Brain — Virus kills haywire stem cells

Breast — The third test’s the charm

A tailored virus, Delta-24-RGD, destroys brain tumor stem cells that resist other therapies and cause lethal regrowth of cancer after surgery, including in the most aggressive brain tumor, glioblastoma multiforme.

Three genomic tests separately predict the likelihood that a patient’s breast cancer will recur after surgery without additional treatment, as well as its vulnerability to chemotherapy or to hormone therapy. Each predictor is independent of the others, providing unique information to physicians and patients considering treatment options.

“We have shown first in lab experiments and then in stem cell-derived human brain cancer in mice, that we have a tool that can target and eliminate the cells that drive brain tumors,” says co-senior author Juan Fueyo, M.D., associate professor in the Department of Neuro-Oncology. Reported in the Sept. 18, 2007, edition of the Journal of the National Cancer Institute.

“Existing genomic tests for breast cancer provide information about future risk in general, but not the likely benefit of each treatment option separate from a patient’s overall prognosis if no treatment followed surgery. It’s important to independently assess these three variables,” says W. Fraser Symmans, M.D., professor in the Department of Pathology. “We’ve put these three predictors together for the intended purpose of providing all the necessary information for physicians and patients to decide on the best therapy or combination of therapies for breast cancer from a single assay,” says Lajos Pusztai, M.D., Ph.D., associate professor in the Department of Breast Medical Oncology. Reported September 2007 at the American Society of Clinical Oncology Breast Cancer Symposium.

Ovarian/breast/ Endometrium — Taking a systems biology approach Researchers used systems biology to identify the PI3K pathway as a therapeutic target for cancer and have developed multiple collaborations with industry to move PI3K pathway-inhibiting drugs alone and in combination forward to patient care in endometrial, ovarian and breast cancer. They also have developed a number of approaches to identify patients likely to respond to this approach.

“The systems biology method provides a powerful predictor of patients likely to respond to therapeutic targeting of the PI3K pathway,” says Gordon Mills, M.D., Ph.D., chair of the Department of Systems Biology. Reported in the August 1, 2008, edition of Cancer Research.

M. D. Anderson Annual Report 2007-2008

Experimental Therapeutics — New treatments advance targeted therapy Two new inhibitor drugs — PX-866 and PX-478 — entered Phase I trials for patients with solid tumors and advanced cancers, respectively, at M. D. Anderson and other institutions. “The success of these two drugs is twofold,” says Garth Powis, D.Phil., chair of the Department of Experimental Therapeutics and director of the Center for Targeted Therapy. “By attacking the ability of tumors to survive stress induced by low oxygen, chemotherapy or radiation therapy, we have discovered a new way to treat cancer and increase the activity of existing therapies. This method, however, also can be used to personalize therapy by matching the presence of the drug’s molecular target in the patient’s tumor with the drug.” •

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PX-866 suppresses the PI3 (phosphotidylinositol-3) kinase pathway that, when activated, decreases patient survival because of its resistance to drugs and radiation therapy. PX-866 stops the growth of tumors, and molecular markers have been identified that may help predict which patients show the best response to the drug. PX-478 blocks HIF-1 (hypoxia-inducible factor 1), which controls tissue response to low oxygen and provides tumors with the ability to create a new blood supply, allowing their survival and growth. PX-478 attacks the ability of these tumors to activate formation of new blood vessels.

Accelerating Cancer Genome Efforts M. D. Anderson has taken a leadership role in obtaining tumors for the Cancer Genome Atlas (TCGA) project in glioma and ovarian and lung cancers. The TCGA is a comprehensive effort to accelerate understanding of the molecular basis of cancer through the application of genome analysis technologies, especially large-scale genome sequencing. The program, sponsored by the National Cancer Institute and the National Human Genome Research Institute, eventually will lead to cancer treatments customized to target genes and gene products that are abnormal in those cancers. Researchers at M. D. Anderson’s Kleberg Center for Molecular Markers, which is part of the Red and Charline McCombs Institute for the Early Detection and Treatment of Cancer, work with the disease site teams to lead the effort to obtain and investigate tumors.

Commitment to to Outreach Commitment Outreach

around the globe

Commitment to Outreach

greater houston area

M. M.D.D.Anderson AndersonAnnual AnnualReport Report2007-2008 2007-2008

serving diverse populations

As M. D. Anderson seeks to expand the reach of its Making Cancer History速 mission, the institution continues to build strong relationships with premier academic, health care and government entities at home and abroad. It also has reached out into the greater Houston community with satellite treatment centers and enhanced its research efforts to include diverse ethnic and underserved populations.

Commitment to Outreach

Extending quality care into the community is a scenario Matthew Ballo clearly relishes. Clinician brings excellence to Houston communities

by Julie Penne

M. D. Anderson Annual Report 2007-2008

Matthew Ballo, M.D.

In this role, he provides clinical excellence as medical director of Radiation Oncology Outreach and head of radiation oncology at the M. D. Anderson Clinical Care Center in the Bay Area (Nassau Bay, Texas). The extra benefit is spending more time with patients and broadening his practice. A radiation oncologist who trained and practiced at the main campus since 2000, Ballo, M.D., recognized early on the opportunities of bringing care to the communities. When he opened the radiation oncology clinic at the Bay Area location in 2007, he joined with two faculty members from medical oncology, Amy Hassan, M.D., and Craig Kovitz, M.D., to launch M. D. Anderson’s first care center beyond the main campus. The center, which is located on the campus of Christus St. John Hospital, has become an epicenter for enhancing oncology care throughout the booming region south of Houston.

“Since we opened, we’ve reached out to meet with general surgeons, community oncologists, pathologists and radiologists to host a weekly tumor board and offer multidisciplinary care,” Ballo says. “It’s been gratifying to share resources and learn from colleagues, but, ultimately, it is the residents of this community who benefit from a higher standard of care.” It also is his role to lead multiple quality assurance programs for each of M. D. Anderson’s six satellite centers. Every Friday, he and the radiation oncologists from the Houston area and Albuquerque facilities gather

for a conference call to review new patient cases, discuss protocols and compare notes on treatment guidelines, all to enhance patient safety and quality of care. “Seeing patients, building a practice and heading up the programs that will ensure excellence wherever M. D. Anderson establishes a satellite is incredibly fulfilling, stimulating and vital work,” he says. “I’m going in new directions that I never expected, but I remain anchored to the institution’s mission and patient focus.”

Commitment to Outreach

Momentum in the Greater Houston Area

Satellites reach outlying communities

Designed to extend M. D. Andersonâ&#x20AC;&#x2122;s expertise, services and mission from the flagship in the Texas Medical Center to growing communities and neighborhoods, the arc of outreach has come nearly full circle around the metropolitan Houston area â&#x20AC;&#x201D; and beyond. With additional satellites planned, M. D. Anderson currently has radiation treatment centers in Bellaire, Bay Area (Nassau Bay), Katy, Fort Bend (Richmond) and The Woodlands in Texas, and in Albuquerque, N.M. The facility in Nassau Bay provides not only radiation treatment, but also medical oncology, laboratory and chemotherapy infusion services, as well as a blood donation center and pharmacy. As at the main campus, each patient treated at a satellite has the benefit of multidisciplinary care and M. D. Anderson expertise.

M. D. Anderson Annual Report 2007-2008

Therapist makes the most of a small window of opportunity by Julie Penne

For Kameka Rideaux, a radiation therapist at the Bellaire Radiation Treatment Center in the greater Houston area, a top priority is helping her patients regain control and power in their lives. While this may be a hope of many radiation therapists in the other satellites or on the main campus, she only has five days to accomplish the goal with some of her patients while her colleagues may have several weeks. Rideaux, a radiation therapist for seven years, cares for women who receive partial-breast irradiation, a new, emerging treatment option for breast cancer patients who undergo lumpectomy.

The Bellaire Radiation Treatment Center is the only M. D. Anderson location to offer the new technique. Using MammoSite® technology, the option is being studied to determine if it is an effective alternative to the current standard of care, which involves removal of the tumor and surrounding tissue followed by four to six weeks of daily external beam radiation. Because she sees her partial-breast irradiation patients for only a week, Rideaux works hard to give them

the comfort and assurance they need and keep them infection-free so they can continue their abbreviated course of treatment and move on with their lives. But like other breast cancer patients or patients with other diagnoses who receive an extended radiation treatment schedule, partial-breast irradiation patients have just as many concerns, questions and fears. “So many patients who come to the Bellaire Radiation Treatment Center are surprised at the level of care they receive, but I’m not suprised at all,” Rideaux says. “It’s our job to provide outstanding treatment and listen to the needs expressed by our patients. Because we are in the community setting, we have the opportunity to slow down a bit and tune into their questions. We are this neighborhood’s link to M. D. Anderson.”

radiation treatment Center opens on Houston’s west side When M. D. Anderson opened a radiation treatment center in Katy in the fall of 2007, it was the fifth satellite center to open in the Houston area and the sixth in the Southwest. In collaboration with Christus St. Catherine Hospital, the center is led by Gregory Chronowski, M.D., assistant professor in the Department of Radiation Oncology. A specialist in treating cancers of the head and neck, Chronowski and his team also care for patients diagnosed Kameka Rideaux

with a range of cancers. This is the second collaboration M. D. Anderson has formed with a Christus hospital in the Houston area. The other is located on the campus of Christus St. John Hospital in Nassau Bay.

Commitment to Outreach

Momentum Around the Globe

M. D. Andersonâ&#x20AC;&#x2122;s reputation for excellence in cancer research, treatment, education and prevention is longstanding. For years, it has shared its experience and expertise with other oncologists and health care professionals around the world. Building on that solid foundation, the institution is developing more formal partnerships and initiatives that will help increase the level of cancer knowledge and, ultimately, decrease the burden of cancer internationally. Teaming with German research center

Searching for the right opportunities

Formalizing an EastWest partnership

Having filled three key leadership positions, the Center for Global Oncology is poised to help M. D. Anderson further share its cancer research and treatment expertise in Texas, the United States and beyond. Vice presidents for global business development (Mitch Latinkic), global academic programs (Karen Fields, M.D.) and global clinical programs (Eduardo Diaz, M.D.) have teamed up to provide a cohesive, strategic approach to new opportunities. The virtual center focuses on educational and research collaborations, clinical business consulting and extending our approach in the care of patients with local, national and international partners.

M. D. Andersonâ&#x20AC;&#x2122;s sister institution agreement with the Sir Y.K. Pao Centre for Cancer and Hong Kong Cancer Institute at the Chinese University of Hong Kong (CUHK) is based on shared missions of scientific discovery, patient care, education and prevention. The two institutions identified nasopharyngeal carcinoma, hepatocellular carcinoma and glioma as initial research focus areas. Additionally, the collaboration aims to establish a clinical trial network among China, East Asia and M. D. Anderson, and educational exchange programs for postgraduate students, clinical fellows and oncology nurses with onsite training opportunities at CUHK.

A sister institution agreement with the German Cancer Research Center (DKFZ) formalized long-standing relationships among faculty at M. D. Anderson and Germanyâ&#x20AC;&#x2122;s premier comprehensive cancer center, which is particularly renowned for excellence in basic cancer research. The National Center for Tumor Diseases at Heidelberg is the clinical arm of DKFZ. Among novel collaborative research projects involving DKFZ and M. D. Anderson is the use of high-throughput, genome-wide RNAi screens in cultured cells to discover genes that, when inactivated, will specifically kill cancer cells but not normal cells.

German cancer Research Center

M. D. Anderson Annual Report 2007-2008

Targeting breast cancer in other countries More than 30 M. D. Anderson scientists and physicians serve on an advisory board for new breast cancer partnerships in Latin America and the Middle East: Mexico

Middle East

M. D. Anderson is the lead United States-based medical partner in a collaborative effort in Mexico to advance progress against breast cancer, the leading cause of cancerrelated deaths among women in that country. Working through the Partnership for Breast Cancer Awareness and Research of the Americas, the effort is driving awareness, research, training, community outreach and women’s empowerment. The initiative teams M. D. Anderson with Asociacion Mexicana contra el Cancer de Mama, A.C., Instituto Nacional de Cancerologia, the U.S. Department of State and Susan G. Komen for the Cure.

In the first solo visit of an American first lady to Saudi Arabia, Laura Bush led a delegation to Riyadh to expand the United States-Middle East Partnership for Breast Cancer Awareness and Research. M. D. Anderson was selected by the U.S. Department of State as the premier medical partner for the initiative. The Middle East is a region where breast cancer is especially prevalent in young women and awareness lags, contributing to a high rate of late-stage breast cancer diagnoses. Saudi Arabia joined Jordan in the collaboration that brings together medical centers in those countries with M. D. Anderson and Susan G. Komen for the Cure.

Lois Ramondetta, M.D., associate professor in the Department of Gynecologic Oncology, operates a clinic and performs surgery each week at Lyndon B. Johnson General Hospital in Houston, where M. D. Anderson partners with this component of the Harris County Hospital District to provide specialized oncology care to the citizens of Texas. Pictured with her is LaToysha Fernandez, a uterine cancer patient.

Momentum Among Diverse Populations Through the Department of Health Disparities in the Division of Cancer Prevention and Population Sciences, M. D. Anderson researchers are involved in research and education initiatives that address disparities in health care, especially among ethnic and underserved populations. Their goal is to reduce, and ultimately eliminate, disparities in cancer incidence, morbidity and mortality, and cancer-related behaviors.

Mexican-Americans in the United States at greater risk for obesity

How environmental influences impact physical activity levels

To better understand the prevalence and growing number of overweight Mexican-Americans, researchers in M. D. Anderson’s Department of Epidemiology set out to discover if birthplace and years of residence in the United States play a factor. The results indicated that Mexican-born men and women have a lower risk of obesity than those born in the United States. However, the longer they stay in the United States, the more they shift towards habits that increase their risk of becoming obese and their chances of getting cancer. “The results are disconcerting, but not necessarily surprising,” says Michele Forman, Ph.D., professor in the Department of Epidemiology. “We need to find out when the shift actually takes place once they arrive in the United States, and how to intervene and persuade them not to shift toward the behaviors that cause obesity.”

Where you live, work and play may impact your overall health. In a combined-data study, researchers determined that social support and available neighborhood facilities have important impacts on physical activity. “Understanding the process of behavior change is key,” said Lorna Haughton McNeill, Ph.D., assistant professor of Health Disparities Research at M. D. Anderson. “We found that peoples’ social and physical environments can affect their desire to be physically active. If there are facilities available, such as parks and other recreational areas, people are more likely to exercise. Additionally, we found motivation through social support particularly influential.”

Commitment to Education

feeding the pipeline

Commitment to Education

ensuring new discoveries

M. D. Anderson Annual Report 2007-2008

serving the community

Integrated with patient care, research and prevention, education advances M. D. Andersonâ&#x20AC;&#x2122;s mission to eliminate cancer in Texas, the nation and the world. Through a wide variety of outstanding programs, the institution is committed to educating undergraduate and graduate students, clinical and research fellows, professionals, employees and the public. The new Research Medical Library in the Pickens Academic Tower (above) enhances educational opportunities with its extensive resources, study areas and computers.

Commitment to Education

M. D. Anderson bears the educational imprint of Michael Ahearn. Educator inspires students as programs expand

by Mary Jane Schier

M. D. Anderson Annual Report 2007-2008

Since arriving at the institution in 1965, he has encouraged the training of hundreds of allied health professionals and promoted science careers for high school and college students. Ahearn, Ph.D., who has held academic administrative appointments for 22 years, has served as founding dean of the School of Health Professions (SHP) since 1998. “Our school prepares health professionals in eight disciplines that provide critical support to patient care and research activities here and at other health care facilities. The Bureau of Labor Statistics predicts that by 2015 we may have a shortage of as many as 2.5 million of these important professionals,” Ahearn notes.

SHP offers one of only seven accredited molecular genetic technology programs and one of fewer than 10 academic programs in medical dosimetry. Other SHP programs include: • • • • •

Clinical laboratory science Cytogenetic technology Diagnostic imaging Histotechnology Radiation therapy

Bachelor of Science degrees are awarded in seven programs, and the Histotechnology Program is working toward degree status.

SHP achievements during the past year include: • Increasing the rigorous laboratory and clinical training for most disciplines from 12 to 24 months to include new and emerging technologies. The majority of students enter after their sophomore year in college. • Marking the first graduation for the three-year Diagnostic Imaging Program with all eight students receiving bachelor’s degrees. • Reaching a total enrollment of 203 students, which is more than double the number from a year ago. • Completing plans to move all SHP classrooms, faculty offices and supporting services to one central location in late 2008. Because many graduates are recruited to work at M. D. Anderson, Ahearn says it has been “enormously satisfying to be an integral part of their training and then see the substantial contributions they are making to our campaign to eradicate cancer.”

Michael Ahearn, Ph.D.

Commitment to Education

Momentum in Education

Educating today for tomorrow

During the last year, more than 5,000 people received training at M. D. Anderson. They included full-time clinical fellows and residents, postdoctoral fellows, graduate students, undergraduate allied health students and an increasing number of nursing students. Practicing physicians, visiting scientists and an array of other health care professionals also rotated for shorter periods of time through the institutionâ&#x20AC;&#x2122;s doors to learn the latest in cancer research and specialized clinical care. Gifted high school and college students along with science teachers worked in multiple research laboratories. And a record number of people benefited from public education programs aimed at raising awareness about cancer risk and motivating them to prevent the disease.

M. D. Anderson Annual Report 2007-2008

Mentor carries on ancient tradition by Mary Jane Schier

Michelle Barton is continuing a tradition that dates back to the ancient Greek poet Homer. As a model mentor for graduate students, she has earned this title that in his epic, “The Odyssey,” describes a wise and trusted teacher. Now almost 30 centuries later, Barton, Ph.D., exemplifies why many M. D. Anderson faculty members are caring mentors to students and trainees in educational programs preparing the next generation of physicians and scientists. “I have had wonderful mentors who helped shape my career, and I enjoy interacting with our incredibly bright

students during their early scientific journeys,” explains Barton, professor in the Department of Biochemistry and Molecular Biology. Since joining M. D. Anderson in 2000, Barton has won multiple awards for her contributions to strengthen training for students at The University of Texas Graduate School of Biomedical Sciences (GSBS). In addition to

mentoring students in her laboratory, she has served on more than 100 students’ advisory, supervisory and examining committees as well as major GSBS policy committees. While co-director and director of the GSBS Genes and Development Program, Barton coordinated a 60page student handbook that became a standard for other programs. She also organized Bioinformatics for Biologists, a course to help students and faculty interpret large amounts of data acquired from gene assays, genomics and proteomics. Barton’s gene expression and tissue regeneration research has allowed her to collaborate with scientists around the world and led to launching an international exchange program with two German institutions last summer. She developed that program as a founding member of M. D. Anderson’s Graduate Education Committee using institutional funds earmarked for improving recruitment of GSBS students. “The four German students who spent 10 weeks working with our researchers learned a great deal, and we plan to host four more this summer. We also expect some GSBS students will visit labs in Germany in the future,” Barton says.

Michelle Barton, Ph.D., and Joseph Taube, graduate research assistant

Postdoctoral fellows ranked M. D. Anderson among the top five workplaces in the United States, according to The Scientist magazine’s annual Best Places to Work for Postdocs Survey. Among key factors were the quality of training and mentoring, career development opportunities and the ability to network with others.

Commitment to Education

reaccreditations keep us moving forward •

The Accreditation Council for Continuing Medical Education reaccredited M. D. Anderson’s comprehensive continuing medical education program with commendation for educational planning, evaluation and administration for the maximum six years. This achievement “represents a great, years-long, ongoing effort” for the nation’s largest oncology CME program, notes Stephen Tomasovic, Ph.D., senior vice president for academic affairs.

•

M. D. Anderson’s oncology education program for physician assistants was one of only two postgraduate programs in the United States to earn a three-year accreditation from the Accreditation Review Commission on Education for the Physician Assistant, reports Maura Polansky, director of the multidisciplinary training program.

•

The University of Texas Police Department that provides public safety services to all M. D. Anderson employees at multiple sites received its fifth three-year accreditation from the Commission on Accreditation for Law Enforcement Agencies Inc.

education highlights The Hematology/Oncology Fellowship Program directed by Robert Wolff, M.D., deputy head of the Division of Cancer Medicine, added a fourth year to give trainees an opportunity for additional research experiences.

The Department of Veterinary Medicine and Surgery accepted its first veterinary resident in January 2008 as part of the new Gulf Coast Consortium Postdoctoral Training Program in Laboratory Animal Medicine. The program is a collaborative effort with Baylor College of Medicine and The University of Texas Health Science Center at Houston to increase specialized training of laboratory veterinarians who support biomedical research.

Physician Oncology Toolkit

M. D. Anderson’s professional nurses broadened their partnerships to increase the pipeline of nursing graduates and enhance the diversity of the nursing workforce. The institution loaned faculty to Texas Woman’s University College of Nursing and The University of Texas School of Nursing at Houston to strengthen training of future nurses. Students from those two schools as well as Houston Baptist University College of Nursing, Prairie View A&M University College of Nursing and The University of Texas Medical Branch at Galveston School of Nursing take clinical rotations here.

Through iTunes U, M. D. Anderson’s educational videos and podcasts

A customized auto-launching jump drive, the award-winning

can now be played and downloaded

Physician Oncology Toolkit is a one-stop resource for physicians with

just like music or other forms of

information on M. D. Anderson news, clinical trials, faculty, speakers,

entertainment. The site,

specialists and more. Information can be updated on a regular basis

www.mdanderson.org/itunes,

through the Internet site: www.mdanderson.org/oncologytoolkit/.

offers a wide variety of content for anyone touched by cancer, from

In 2008, the Public Education Office passed the 1 million mark of people served annually through community outreach events, materials about cancer risk reduction, Internet site links, health fair exhibits, presentations to schools and worksites, tours and other specialized programs. The askMDAnderson service helped 107,475 people this past year via the telephone and online.

the latest treatments to caregiving and complementary modalities.

M. D. Anderson Annual Report 2007-2008

One employee’s grassroots effort by Mary Brolley

Vaithianathan “V.K.” Dorai, Ph.D., is a big picture guy. A senior informatics analyst in the Department of Performance Improvement, he helps internal clients examine and improve their efficiency and productivity. For example, one project involved tracking clinic traffic to determine space needs in advance of a redesign. But to grasp the big picture of how the institution runs — and where it’s headed — Dorai likes to get away from computer screens, numbers and spreadsheets.

So he volunteers for a number of M. D. Anderson’s outreach and education programs. As an employee ambassador for the Public Education Office, he gives walking tours of the institution. He also works with researchers at M. D. Anderson’s Center for Research on Minority Health in the area of South Asian health issues and is part of the institution’s medical mission group.

His most fulfilling volunteer effort is staffing health fairs in and near Pearland, Texas, home to many immigrants from South Asia. Although he left India 25 years ago, he can still identify with their concerns. Life in the United States offers fewer opportunities to walk and a richer diet, and the incidence of cancer is higher. So when it comes to cancer, he says, “They may need guidance. In India, few people have health insurance. So when South Asian immigrants come to the United States, they may not be in the habit of getting check-ups or cancer screenings.” That’s why Dorai gets out there on behalf of M. D. Anderson — to educate. He hands out literature, fields questions, makes connections. People talk to him. “It may help for them to see a fellow Indian — a familiar face. Someone speaking their language.” Dorai relishes the interaction. “It’s a way for me to give something back to the community and to the institution,” he says.

Vaithianathan Dorai, Ph.D.

A new Graduate Education Committee chaired by Gary Gallick, Ph.D., professor in the Department of Genitourinary Medical Oncology, took major steps to enhance recruitment of top-tier graduate students and increase faculty participation in training future scientists in their laboratories. Improved graduate student recruitment tools include a revamped institutional Internet site and evolving webbased tools such as Facebook and chat rooms. Additional support also was secured for student stipends.

Commitment to Development

fundraising events

Commitment to Development

foundation gifts

M. D. Anderson Annual Report 2007-2008

research funding

Philanthropy plays as vital a role today as it did in M. D. Anderson’s beginning, when money appropriated by the Texas Legislature was matched by the M. D. Anderson Foundation to establish this institution to investigate and treat cancer. With private support providing “seed” money for innovative ideas, researchers are able to successfully compete for federal funding. Philanthropy also aids in recruiting new faculty, propels scientific findings from the labs to the clinics, and allows for the creation of programs that look beyond treatment to prevention and survivorship issues. Each gift to M. D. Anderson carries with it hope for a future free from cancer.

Commitment to Development

Small gifts, huge impact

Unrestricted funds provide critical bridge for research

by DeDe DeStefano

M. D. Anderson Annual Report 2007-2008

Joseph McCarty, Ph.D.

In December 2007, Joseph McCarty, Ph.D., assistant professor in the Department of Cancer Biology, found himself facing a tough decision. He could take a 20 percent cut in support from the National Cancer Institute for his research program over five years, or risk a gap in the substantial progress his team was making against brain cancer while he reapplied for a larger federal grant. A 20 percent cut would mean his lab would be limited in its ability to perform experiments aimed at studying fundamental mechanisms underlying brain tumor initiation and progression. But reapplying for a grant would take several months, and his resources already were severely depleted. Tightening of funding for research is a common problem in academic medicine today because the NCI only can fund 15 percent of the grants that are approved by peer review.

Fortunately, M. D. Anderson’s bridge funding program bought him some crucial extra time. Philanthropic gifts to the institution’s annual fund help provide bridge funding for talented scientists who “just miss” the cutoff. “Bridge funds carried my lab through nine months of research at a very critical time during the program. My lab was quite productive, and I had originally applied for a National Institutes of Health grant, but the peer-reviewed score was just outside the funding range by a couple of percentage points. I could have accepted an offer that the NIH grant program manager made, but my research allotment would have taken a nearly $200,000 cut over a five-year period,” McCarty says. “The bridge funds were instrumental in keeping my lab going, paying salaries and making essential purchases of supplies and equipment.”

The $104,000 McCarty received in bridge funds enabled him to successfully compete for new federal funding of nearly $1.1 million over a five-year period. “The bridge funds provided by M. D. Anderson have enabled my group to make several exciting findings related to how brain tumor cells co-opt blood vessels,” McCarty says. “This may eventually lead to new strategies to inhibit these processes in patients with malignant brain cancer.” Unrestricted gifts to M. D. Anderson are pooled together and distributed to the greatest areas of need. In 2008, the institution received more than 110,000 donations to its annual fund from about 76,000 individuals, totaling $10.8 million. The average gift was just under $100.

Commitment to Development

Duncan family energizes M. D. Anderson’s prevention program The Dan L. Duncan Family Foundation propelled M. D. Anderson’s prevention program to a new level through a $35 million gift designed to help people reduce the risk of cancer and take measures against the disease. The donation was the largest gift made to the institution’s prevention program and the second largest in M. D. Anderson’s history. “The Duncans’ generosity will ensure accelerated progress toward pioneering new prevention methods and increased awareness of genetic predisposition to cancer, as well as the importance of behavior modification and potential therapy options to remain cancer-free,” says M. D. Anderson President John Mendelsohn, M.D. The gift established the Duncan Family Institute for Cancer Prevention and Risk Assessment, which encompasses numerous programs developed within the Division of Cancer Prevention and Population Sciences and will build on the division’s success in integrating basic, clinical and public health research.

Special programs and events, such as the annual Polo on the Prairie, accelerate fundraising efforts for M. D. Anderson.

M. D. Anderson Annual Report 2007-2008

Momentum in Development

Planned giving: On the road to new discoveries by Sarah Watson

When Pat and Jerry Abbott of Pharr, Texas, began their journey together as a married couple, they didn’t plan to make M. D. Anderson one of their stops along the way. But Jerry’s diagnosis of colon cancer two years ago provided an unexpected detour for the recently retired couple. Diagnosed in Corpus Christi, Jerry faced surgery and knew his next decision would be a driving influence in his recovery. Recalling wife Pat’s trip to M. D. Anderson years ago for a second opinion on a suspicious mole (it proved not to be cancerous), he insisted on heading straight for Houston.

“I wanted to go to M. D. Anderson because of its reputation as a worldclass cancer center,” Jerry says. “The doctors there perform more surgeries to treat specific cancers in one week than others do in a year. I wanted to go where cancer is the specialty.” Today Jerry is cancer-free. He says if he ever wins the lottery, “I’ll give it all to M. D. Anderson.”

In the meantime, the Abbotts travel the country in their snazzy new recreational vehicle, occasionally parking it in Houston for Jerry’s six-month checkups. Cancer has been a bump in the road, to be sure. But this forward-thinking couple is using their experience to help M. D. Anderson move mountains in the fight against the disease.

Once at M.D. Anderson, the Abbotts were “amazed and pleased” on every level — so much so that they’ve structured their planned giving to include three charitable gift annuities, plus an additional gift through their estate. They’re proud that one day their contributions will support research in which they’re particularly interested, such as that of Lorenzo Cohen, Ph.D., director of the Integrative Medicine Program, and Frank Marini, Ph.D., associate professor in the Department of Stem Cell Transplantation Research.

pat and Jerry abbott

Sharon Dent, Ph.D., professor and deputy chair of the Department of Biochemistry and Molecular Biology, was chosen for the 2008 Business and Professional Women’s/Texas Award.

Commitment to Development

Wearing pink jerseys in support of the fight against breast cancer, U.S. Women’s National Team members celebrate their victory over Canada. The U.S. Soccer Federation and the Women’s National Team contributed more than $31,000 from an online auction of the jerseys to breast cancer research at M. D. Anderson. All 18 game-worn and autographed jerseys received bids, with winning bids ranging from $920 to $4,100.

Laurence J.N. Cooper, M.D., Ph.D., associate professor in the Department of Pediatrics, received a 2008 Clinical Scientist Award from the Burroughs Wellcome Fund.

One family’s dedication to brain cancer research

Koch gift fuels progress in prostate cancer research

The recently dedicated Chris Anthony Library in the Department of NeuroOncology at M. D. Anderson honors one family’s dedication to propel brain cancer research. Through contributions of more than $500,000 to the Chris Anthony Brain Tumor Research Fund, their efforts are helping researchers and clinicians make great strides in fighting the disease. The Head for the Cure 5K Run/Walk they established in memory of the Overland, Kan., businessman, who succumbed to glioblastoma multiforme in 2003, helps fuel the Brain Tumor Trials Collaborative led by M. D. Anderson. Investigating new treatments for malignant brain tumors, the multi-institution effort includes a number of clinical trials such as a study of sorafenib, an antiangiogenic agent used to treat other solid tumors. Preclinical and early clinical testing suggests the drug may be effective in curbing the growth of glioblastomas as well.

As executive vice president and one of the principals of Koch Industries, David Koch is well known in business as a motivator, a forward-thinker and someone who is results-oriented. Recently, he brought that energy to M. D. Anderson through $18 million to fuel the progress against prostate cancer. Koch is a 16-year survivor of the disease, and his gift established the David Koch Center for Applied Research in Genitourinary Cancers under the direction of his doctor, Christopher Logothetis, M.D., chair of the Department of Genitourinary Medical Oncology. “The goal is to create a unique infrastructure that enables us to take abundant discovery more efficiently and more reliably into human studies,” Logothetis says. Koch also donates his time to M. D. Anderson, serving on the Board of Visitors since 1999 and hosting events.

M. D. Anderson Annual Report 2007-2008

Young cancer patient inspired to start a foundation by DeDe DeStefano

In July 2005, at the age of 36, Rich Lobo was enjoying an exciting career in Chicago, spending time with his beautiful wife, Kathy, and two young children when he began experiencing pain in his right hip. He visited his orthopedist, who initially believed the pain to be from a pulled muscle or inflammation of an old sports injury. However, an MRI detected a large mass in his pelvis. When a biopsy revealed liposarcoma, a disease of the soft tissue with a five-year survival rate of less than 50 percent, Lobo was stunned. “I was scared that the long life that I had always planned to spend with my family was going to be cut short, and I was saddened by the prospect of my young children growing up without their father,” he says. Lobo immediately came to M. D. Anderson, where Raphael Pollock, M.D., Ph.D., head of the Division of Surgery, and a team of specialists met him.

“My wife and I were comforted by the multidisciplinary approach. It made us feel like we were getting a comprehensive view from numerous specialists who saw this disease every day. I trusted them and was determined to fight this disease. I knew that the way to do that effectively would require proactively finding the best doctors and putting my care in their hands,” he continues. After an aggressive regimen of chemotherapy, followed by radiation and surgery to remove the tumor, Lobo now is cancer-free. “Given the experience we had at M. D. Anderson, my wife and I wanted to give back in some way. We knew Dr. Pollock was in the process of creating a sarcoma research center, and we knew we wanted to help.”

The Lobos formed a not-for-profit organization dedicated to raising funds to support sarcoma research. Through fundraisers and corporate donations, their Sarcoma Research Foundation has donated more than $250,000 to M. D. Anderson’s Sarcoma Research Center. “We wanted to do it because sarcoma is a rare disease, so despite the poor survival rate, research is badly underfunded. The idea is to raise awareness, as well as resources,” Lobo says. “We intend to continue to partner with M. D. Anderson fighting this disease to make a difference in the lives of both current and future sarcoma patients.”

the Lobo Family

M. D. Anderson Faculty

M. D. Anderson Management Committee *John Mendelsohn, M.D.

R. Dan Fontaine, J.D.

Ernest T. Hawk, M.D.

Robert F. Gagel, M.D.

President

Senior vice president for business affairs

*Thomas W. Burke, M.D.

Gerard J. Colman

Vice president and head, Division of Cancer Prevention and Population Sciences

Professor and head, Division of Internal Medicine

Executive vice president and physician-in-chief

Senior vice president and chief of clinical operations

Adrienne C. Lang Vice president for center programs

Professor and chair, Department of Radiation Oncology

Thomas A. Buchholz, M.D.

*Raymond N. DuBois, M.D., Ph.D.

Stephen P. Tomasovic, Ph.D.

Provost and executive vice president

Senior vice president for academic affairs

Dwain Morris

Guillermina Lozano, Ph.D.

Vice president and chief financial officer

Harry R. Gibbs, M.D.

Shibu Varghese

Professor and chair, Department of Genetics

Vice president for institutional diversity

Vice president for human resources

*Leon J. Leach Executive vice president and chief business officer

*Executive Committee

M. D. Anderson Faculty

Division of Anesthesiology and Critical Care Division head

Thomas W. Feeley, M.D. Department of Anesthesiology and Perioperative Medicine Associate professor and chair Ad Interim

Vijaya Gottumukkala, M.D. Professors

Mohamed Attala, M.D. Joseph S. Chiang, M.D. David Ferson, M.D. Howard B. Gutstein, M.D. Debra L. Kennamer, M.D. Edward D. Moss, M.D. Peter H. Norman, M.D. Vivian H. Porche, M.D. Tom F. Rahlfs, M.D. Marc A. Rozner, M.D., Ph.D. Dilip R. Thakar, M.D. Dam-Thuy Truong, M.D. Olivier C. Wenker, M.D. Associate Professors

Krishna Boddu, M.D. Thao P. Bui, M.D. John C. Frenzel, M.D. Farzin Goravanchi, D.O. Curtis E. Hightower, M.D., D.V.M. Peter W. Hsu, M.D. Alicia M. Kowalski, M.D. David C. Mackey, M.D. Keyuri U. Popat, M.D.

Ronaldo V. Purugganan, M.D. Kenneth J. Sapire, M.D. Una Srejic, M.D. Angela Truong, M.D. Assistant professors

Tayab Andrabi, M.D. Radha Arunkumar, M.D. Jeffrey Cerny, M.D. Shao-Rui Chen, M.D. Lori Dangler, M.D. Katy Elizabeth French, M.D. Roxana Grasu, M.D. Timothy Albert Jackson, M.D., Ph.D. Spencer Stephen Kee, M.D. Piotr A. Kwater, M.D. Jeffrey Lim, M.D. Gabriel Eduardo Mena, M.D. Linh T. Nguyen, M.D. Pascal Owusu-Agyemang, M.D. Ronald N. Parris, M.D. Elena Potylchansky, M.D. Yury Potylchansky, M.D. Elizabeth Rebello, M.D. Joseph R. Ruiz, M.D. Mona G. Sarkiss, M.D., Ph.D. Jagtar Singh Heir, D.O. Jose Soliz, M.D. Jackson Su, M.D. Benjamin Wallisch, D.O. Steve Wang, M.D.

Instructors

Charles Eugene Cowles, M.D. Shannon Michelle Gossett, M.D. Allen Alexander Holmes, M.D. Maggie Jeffries, M.D. Department of Critical Care Professor and chair

Kristen J. Price, M.D. Professors

Gregory H. Botz, M.D. Joseph L. Nates, M.D. Associate professor

Karen Chen, M.D.

Assistant Professors

Donna M. Calabrese, M.D. John W. Crommett, M.D. Diego Hernan de Villalobos, M.D. Susan Gaeta, M.D. Sajid Haque, M.D. De Li, M.D. Imrana Malik, M.D. Selvaraj Egbert Pravinkumar, M.D. Nisha Rathi, M.D.

Department of Pain Medicine Professor and chair Ad Interim

Allen Wade Burton, M.D. Professors

Patrick M. Dougherty, Ph.D. Larry C. Driver, M.D. Diane M. Novy, Ph.D. Associate professors

Dhanalakshmi Koyyalagunta, M.D. Zhizhong Z. Pan, Ph.D. Assistant professors

Rodolfo Gebhardt, M.D. Basem Hamid, M.D. Marco R. Perez Toro, M.D. Phillip Phan, M.D. Joseph Ting, D.O. Han-Rong Weng, M.D., Ph.D.

M. D. Anderson Annual Report 2007-2008

Division of Cancer Medicine Division head

Waun Ki Hong, M.D.

Department of Breast Medical Oncology Professor and chair

Gabriel N. Hortobagyi, M.D. Professors

Daniel J. Booser, M.D. Aman U. Buzdar, M.D. Nuhad K. Ibrahim, M.D. James L. Murray III, M.D. Richard L. Theriault, D.O. Vicente Valero, M.D. Ronald S. Walters, M.D. Associate Professors

Banu K. Arun, M.D. Massimo Cristofanilli, M.D. Francisco J. Esteva, M.D., Ph.D. Sharon Hermes Giordano, M.D. Marjorie C. Green, M.D. Lajos Pusztai, M.D., Ph.D. Naoto T. Ueno, M.D., Ph.D. Assistant Professors

Eleni Andreopoulou, M.D. Ana Maria Gonzalez-Angulo, M.D. Kimberly Brooke Koenig, M.D. Jennifer Litton, M.D. Phuong Khanh Morrow, M.D. Stacy Moulder, M.D. Department of Experimental Therapeutics Professor and chair

Garth Powis, D.Phil. Professors

Bharat B. Aggarwal, Ph.D. Robert C. Bast Jr., M.D. William G. Bornmann, Ph.D. Mauro Ferrari, Ph.D. Varsha V. Gandhi, Ph.D. Elizabeth A. Grimm, Ph.D. Walter N. Hittelman, Ph.D. Constantin Ioannides, Ph.D. Abdul R. Khokhar, Ph.D. Chang-Gong Liu, Ph.D. Gabriel Lopez-Berestein, M.D. Kapil Mehta, Ph.D. John Mendelsohn, M.D. William K. Plunkett Jr., Ph.D. Waldemar Priebe, Ph.D. Fredika Robertson, Ph.D. Michael G. Rosenblum, Ph.D. Zahid H. Siddik, Ph.D. Leonard A. Zwelling, M.D. Associate Professors

George A. Calin, M.D., Ph.D. Julie A. Ellerhorst, M.D., Ph.D. Zhen Fan, M.D. Giuliana J. Izzo, M.D. Mary Jane Johansen, Pharm.D. Jian Kuang, Ph.D.

Xiao-Feng Le, M.D., Ph.D. Warren S. Liao, Ph.D. Xiuping Liu, M.D. Timothy L. Madden, Pharm.D. John S. McMurray, Ph.D. Nancy J. Poindexter, Ph.D. Ana M. Tari, Ph.D. Assistant Professors

Geoffrey Bartholomeusz, Ph.D. Bryant G. Darnay, Ph.D. Wuguo Deng, Ph.D. Suhendan Ekmekcioglu, Ph.D. Yong Liao, Ph.D. Deepa Sampath, Ph.D. Taly Spivak-Kroizman, Ph.D. Christine Stellrecht, Ph.D. Shuxing Zhang, Ph.D. Instructors

Kumudha Balakrishnan, Ph.D. Lisa S. Chen, Ph.D. Rong Chen, Ph.D. Izabela Fokt, Ph.D. Yon Kim, Ph.D. Betty Lamothe, Ph.D. Xinqun Li, M.D., Ph.D. Xiaojun Liu, Ph.D. Khalid Amanali Mohamedali, Ph.D. Bulent Ozpolat, M.D., Ph.D. Ann Marie Simeone, Ph.D. Ryan Watkins, Ph.D. Chuan-Fen Wu, Ph.D. Department of Gastrointestinal Medical Oncology Professor and chair

James L. Abbruzzese, M.D. Professors

Jaffer A. Ajani, M.D. Raymond N. DuBois, M.D., Ph.D. Donghui Li, Ph.D. Robert A. Wolff, M.D. Associate Professors

Cathy Eng, M.D. Christopher Garrett, M.D. Milind Javle, M.D. Gauri R. Varadhachary, M.D. Keping Xie, M.D., Ph.D. James C. Yao, M.D. Assistant Professors

David Z. Chang, M.D., Ph.D. David Fogelman, M.D. Katrina Glover, M.D. Manal M. Hassan, M.D., Ph.D. Linus Ho, M.D., Ph.D. Ahmed Kaseb, M.B.B.S. Edmund Scott Kopetz, M.D. Michael James Overman, M.D. Alexandria Phan, M.D. Shrikanth A. Reddy, Ph.D.

Instructors

Daoyan Wei, Ph.D. Yixin Yao, Ph.D. Department of General Oncology associate professor and chair Ad Interim

Michael J. Fisch, M.D.

Associate Professors

Daniel Epner, M.D. Moshe Frenkel, M.D.

Assistant Professors

Karin Hahn, M.D. Amy Hassan, M.D. Nikesh Jasani, M.D. Craig Adam Kovitz, M.D. Sunil M. Patel, M.D. Shirisha Reddy, M.D. Amit Sarma, M.D., Ph.D. Peiying Yang, Ph.D.

Instructors

Khoi Chu, Ph.D. Tihui Fu, M.D., Ph.D. Lawrence Tsao, M.D. Zhibo Yang, Ph.D. Department of Gynecologic Medical Oncology Professor and chair

Maurie Markman, M.D. Assistant professor

Bryan Thomas Joseph Hennessy, M.D. Department of Investigational Cancer Therapeutics Professor and chair

Razelle Kurzrock, M.D.

Assistant Professors

Professor and chair

Gerald S. Falchook, M.D. David Hong, M.D. Aung Naing, M.D. Apostolia Maria Tsimberidou, M.D., Ph.D. Jennifer Jane Wheler, M.D.

Professors

Ji Wu, M.D.

Department of Genitourinary Medical Oncology Christopher J. Logothetis, M.D. Wadih Arap, M.D., Ph.D. William Benedict, M.D. Gary Gallick, Ph.D. Renata Pasqualini, Ph.D. Timothy Thompson, Ph.D. Associate Professors

Richard E. Giles, Ph.D. Jeri Kim, M.D. Sankar N. Maity, Ph.D. Paul Mathew, M.D. Randall E. Millikan, M.D., Ph.D. Nora M. Navone, M.D., Ph.D. Lance C. Pagliaro, M.D. Nizar M. Tannir, M.D. Shi-Ming Tu, M.D. Assistant Professors

Ana Aparicio, M.D. John Charles Araujo, M.D. Paul Corn, M.D., Ph.D. Eleni Efstathiou, M.D., Ph.D. Daniel Floryk, Ph.D. Alexei Goltsov, Ph.D. Ivan P. Gorlov, Ph.D. Eric Jonasch, M.D. Likun Li, Ph.D. Padmanee Sharma, M.D., Ph.D. Arlene Odelia Siefker-Radtke, M.D. Salahaldin Tahir, Ph.D. Guang Yang, Ph.D. Xin-Qiao Zhang, M.D., Ph.D. Jain Zhou, M.D., Ph.D. Amado Zurita-Saavedra, M.D.

Instructor

Department of Leukemia Professor and chair

Hagop M. Kantarjian, M.D. Professors

Jorge E. Cortes-Franco, M.D. Zeev Estrov, M.D. Emil J Freireich, M.D. Jean-Pierre Issa, M.D. Michael J. Keating, M.B. Charles A. Koller, M.D. Susan Oâ&#x20AC;&#x2122;Brien, M.D. Associate Professors

Stefan H. Faderl, M.D. Alessandra Ferrajoli, M.D. Guillermo Garcia-Manero, M.D. Farhad Ravandi-Kashani, M.D. Deborah A. Thomas, M.D. Srdan Verstovsek, M.D. William G. Wierda, M.D., Ph.D. Assistant Professors

Gautam Borthakur, M.B.B.S. Jan Andreas Burger, M.D. Elias Joseph Jabbour, M.D. Jaroslav Jelinek, M.D., Ph.D. Tapan Mahendra Kadia, M.D. Marina Konopleva, M.D., Ph.D. Shao-Qing Kuang, Ph.D. Gloria N. Mattiuzzi, M.D. Lanlan Shen, M.D., Ph.D. Continued ...

M. D. Anderson Faculty Division of Cancer Medicine (continued)

Instructors

Marcos Roberto Estecio, Ph.D. Yue Wei, Ph.D. Department of Lymphoma/Myeloma Professor and chair

Larry W. Kwak, M.D., Ph.D. Professors

Fredrick B. Hagemeister, M.D. Peter W. McLaughlin, M.D. Alma Rodriguez, M.D. Jorge E. Romaguera, M.D. Qing Yi, M.D., Ph.D. Anas Younes, M.D. Associate Professors

Luis E. Fayad, M.D. Robert Orlowski, M.D., Ph.D. Barbara Pro, M.D. Felipe Samaniego, M.D. Donna M. Weber, M.D. Assistant Professors

Michelle A. Fanale, M.D. Nathan Fowler, M.D. Sattva S. Neelapu, M.D. Jatin Shah, M.D. Sheeba Koshy Thomas, M.D. Michael Wang, M.D. Instructors

Zuzana Berkova, Ph.D. Soung-Chul Cha, Ph.D. Jing Yang, Ph.D. Lin Yang, Ph.D. Department of Melanoma Medical Oncology

Professor and chair

W.K. Alfred Yung, M.D. Professors

Charles A. Conrad, M.D. Mark R. Gilbert, M.D. Victor A. Levin, M.D. Christina A. Meyers, Ph.D. Associate Professors

Arthur D. Forman, M.D. Juan Fueyo-Margareto, M.D. Maria-Magdalena Georgescu, M.D., Ph.D. Morris D. Groves, M.D., J.D. Vinaykumar K. Puduvalli, M.D. John M. Slopis, M.D. Assistant Professors

Howard Colman, M.D., Ph.D. John Frederick de Groot, M.D. Candelaria Gomez-Manzano, M.D. Hong Jiang, Ph.D. Dimpy Koul, Ph.D. Monica Elena Loghin, M.D. Zhimin Lu, M.D., Ph.D. Sudhakar Tummala, M.D. Jeffrey Scott Wefel, Ph.D. Karin Woodman, M.D. Jun Yao, Ph.D. Instructors

Marta M. Alonso, Ph.D. Juinn-Lin Liu, Ph.D. Mariana Erika Witgert, Ph.D. Yan Xia, Ph.D.

Professor and chair

Patrick Hwu, M.D.

Department of Palliative Care and Rehabilitation Medicine

Professors

Eduardo Bruera, M.D.

Agop Y. Bedikian, M.D. Wen-Jen Hwu, M.D., Ph.D. Nicholas E. Papadopoulos, M.D. Associate Professors

Kevin Kim, M.D. Laszlo Radvanyi, Ph.D.

Assistant Professors

Gregory A. Lizee, Ph.D. Willem Overwijk, Ph.D. Dapeng Zhou, M.D., Ph.D. Michael Davies, M.D., Ph.D. Jade Homsi, M.D. Instructors

Yanyan Lou, M.D., Ph.D. Vashisht Gopal Yennu Nanda, Ph.D.

Department of Neuro-Oncology

Professor and chair Professor

Donna S. Zhukovsky, M.D. Associate Professors

Ahmed Elsayem, M.D. Ying Guo, M.D. Suresh K. Reddy, M.D. Ki Y. Shin, M.D. J. Lynn Palmer, Ph.D.

Assistant Professors

Shalini Dalal, M.D. Egidio Del Fabbro, M.D. Rony Dev, D.O. Nada Abdellatif Fadul, M.D. Jack Fu, M.D. Benedict Konzen, M.D. Paul W. Walker, M.D. Rajesh R. Yadav, M.D. Sriram Yennu, M.D.

Department of Sarcoma Medical Oncology Professor and chair

Robert S. Benjamin, M.D. Professors

Shreyaskumar Patel, M.D. Saroj Vadhan, M.D. Associate professor

Jonathan C. Trent II, M.D., Ph.D. Assistant Professors

Dejka Marida Araujo, M.D. Joseph A. Ludwig, M.D. Vinod Ravi, M.B.B.S. Department of Stem Cell Transplantation and Cellular Therapy Professor and chair

Richard E. Champlin, M.D. Professors

Paolo Anderlini, M.D. Borje S. Andersson, M.D., Ph.D. Michael Andreeff, M.D., Ph.D. Sergio A. Giralt, M.D. Roy Jones, M.D., Ph.D. Issa F. Khouri, M.D. Martin Korbling, M.D. Steven M. Kornblau, M.D. John D. McMannis, Ph.D. Jeffrey J. Molldrem, M.D. Elizabeth Shpall, M.D. Associate Professors

Marcos Jose Garcia de Lima, M.D. Chitra Hosing, M.D. Yago Nieto, M.D., Ph.D. Uday R. Popat, M.D. Muzaffar H. Qazilbash, M.D. Assistant Professors

Amin Majid Alousi, M.D. Bing Z. Carter, Ph.D. Stefan Octavian Ciurea, M.D. Partow Kebriaei, M.D. Sijie Lu, Ph.D. Qing Ma, Ph.D. Frank C. Marini III, Ph.D. Gabriela Rondon, M.D. Rima M. Saliba, Ph.D. Benigno Valdez, Ph.D. Rui-Yu Wang, M.D., Ph.D. Instructors

Gheath Al-Atrash, Ph.D. Paul Michael Armistead, Ph.D. Xiaoyang Ling, Ph.D. Ismael J. Samudio, Ph.D. Weiguo Zhang, M.D., Ph.D.

Department of Systems Biology Professor and chair

Gordon B. Mills, M.D., Ph.D. Associate Professors

Francois-Xavier Claret, Ph.D. Yiling Lu, M.D. Honami Naora, Ph.D. Assistant Professors

Gabor Balazsi, Ph.D. Kwai Cheng, Ph.D. Valsala Haridas, Ph.D. Ju-Seog Lee, Ph.D. Jiyong Liang, Ph.D. Shiaw-Yih Lin, Ph.D. Prahlad Ram, Ph.D. Zhi-Xiang Xu, M.D., Ph.D. Instructors

Mark S. Carey, M.D. Zhiyong Ding, Ph.D. Kathleen M. Gajewski, Ph.D. Katherine Stemke Hale, Ph.D. Department of Thoracic/ Head and Neck Medical Oncology Professor and chair

Scott M. Lippman, M.D. Professors

Frank V. Fossella, M.D. Bonnie S. Glisson, M.D. Roy S. Herbst, M.D., Ph.D. Daniel D. Karp, M.D. Merrill S. Kies, M.D. Jonathan M. Kurie, M.D. Reuben Lotan, Ph.D. Li Mao, M.D. Katherine M. Pisters, M.D. David J. Stewart, M.D. Associate Professors

George R. Blumenschein, M.D. Ho-Young Lee, Ph.D. Charles Lu, M.D. Vassiliki A. Papadimitrakopoulou, M.D. Anita L. Sabichi, M.D. Ralph G. Zinner, M.D. Assistant Professors

Heidi S. Erickson, Ph.D. Ja Koo, Ph.D. John Victor Heymach, M.D., Ph.D. Faye M. Johnson, M.D., Ph.D. Edward S. Kim, M.D. Hai T. Tran, Pharm.D. Anne Tsao, M.D. Instructors

Carmen Behrens, M.D. Nitin Chakravarti, Ph.D. Jiong Deng, Ph.D. Matthew H. Herynk, Ph.D. Joerg J. Jacoby, Ph.D. Woo-Young Kim, Ph.D.

M. D. Anderson Annual Report 2007-2008

Division of Cancer Prevention and Population Sciences

Division of Diagnostic Imaging Division head

Donald A. Podoloff, M.D.

Vice president and division head

Ernest T. Hawk, M.D. Department of Behavioral Science Professor and chair

Ellen R. Gritz, Ph.D. Professors

Walter F. Baile, M.D. Karen M. Basen-Engquist, Ph.D. Paul M. Cinciripini, Ph.D. Lorenzo Cohen, Ph.D. Wendy Demark-Wahnefried, Ph.D. Alexandre V. Prokhorov, M.D., Ph.D. Leslie R. Schover, Ph.D. Associate Professors

Janice Blalock, Ph.D. Cindy L. Carmack Taylor, Ph.D. Susan K. Peterson, Ph.D. Assistant Professors

Hoda Badr, Ph.D. Brian L. Carter, Ph.D. Ludmila M. Cofta-Woerpel, Ph.D. Michelle Cororve Fingeret, Ph.D. Maher Karam-Hage, M.D. Patricia Ann Parker, Ph.D. Jason D. Robinson, Ph.D. Damon J. Vidrine, Dr.P.H. Instructors

Cho Lam, Ph.D. Jennifer Minnix, Ph.D. Eileen Shinn, Ph.D. Francesco Versace, Ph.D. Department of Clinical Cancer Prevention Professor and chair AD Interim

Ernest T. Hawk, M.D.

Associate Professors

Therese Bartholomew Bevers, M.D. Elise D. Cook, M.D. Lewis E. Foxhall, M.D. Ashraful M. Hoque, M.D., Ph.D. Imad Shureiqi, M.D. Xiaochun Xu, M.D., Ph.D. Assistant Professors

Associate Professors

Shine Chang, Ph.D. Randa El-Zein, M.D., Ph.D. Sanjay Shete, Ph.D. Sara S. Strom, Ph.D. Assistant Professors

Carol J. Etzel, Ph.D. Olga Y. Gorlova, Ph.D. Jian Gu, Ph.D. Jie Lin, Ph.D. Somdat Mahabir, Ph.D. Cielito C. Reyes-Gibby, Dr.P.H. Paul A. Scheet, Ph.D. Li-E Wang, M.D. Anna Victoria Wilkinson, Ph.D. Chih-Chieh Wu, Ph.D. Instructors

Jianzhong Ma, Ph.D. Bo Peng, Ph.D. Larkin Strong, Ph.D. Michael D. Swartz, Ph.D. Chongjuan Wei, Ph.D. Yuanqing Ye, Ph.D. Department of Health Disparities Research Professor and chair

David W. Wetter, Ph.D. Professor

Lovell A. Jones, Ph.D. Associate professor

Harry R. Gibbs, M.D.

Assistant Professors

Jennifer Irvin Vidrine, Ph.D. Lorna Haughton McNeill, Ph.D. Lorraine R. Reitzel, Ph.D. Instructors

Janice A. Chilton, Dr.P.H. Maria A. Hernandez-Valero, Ph.D., Dr.P.H. Carlos A. Mazas, Ph.D. Isabel Torres, Dr.P.H.

Abenaa Brewster, M.D. Lonzetta L. Newman, M.D. Instructor

Xiangsheng Zuo, M.D., Ph.D. Department of Epidemiology Professor and chair Ad Interim

Robert M. Chamberlain, Ph.D. Professors

Christopher I. Amos, Ph.D. Melissa L. Bondy, Ph.D. Michele Forman, Ph.D. Marsha L. Frazier, Ph.D. Qingyi Wei, M.D., Ph.D. Xifeng Wu, M.D., Ph.D.

Department of Psychiatry Professor and chair Ad Interim

Alan D. Valentine, M.D. Professor

James Desmond Duffy, M.D.

Department of Diagnostic Radiology Professor and chair Ad Interim

Marshall E. Hicks, M.D. Professors

Deepak G. Bedi, M.D. Chusilp Charnsangavej, M.D. Marvin H. Chasen, M.D. Haesun Choi, M.D. Peter J. Dempsey, M.D. Joel S. Dunnington, M.D. Beth S. Edeiken-Monroe, M.D. Farzin Eftekhari, M.D. Jeremy Erasmus Jr., M.D. Bruno D. Fornage, M.D. Lawrence E. Ginsberg, M.D. Leena Ketonen, M.D., Ph.D. Ashok J. Kumar, M.D. Rajendra Kumar, M.D. Evelyne M. Loyer, M.D. John E. Madewell, M.D. Edith M. Marom, M.D. Aurelio Matamoros Jr., M.D. Kevin W. McEnery, M.D. William A. Murphy Jr., M.D. Suhas Parulekar, M.D. Bharat Raval, M.D. Barry I. Samuels, M.D. Carl Sandler, M.D. Paul M. Silverman, M.D. Datla G. Varma, M.D. David C. Vining, M.D. Gary J. Whitman, M.D. Kenneth C. Wright, Ph.D. Associate Professors

Kamran Ahrar, M.D. Tzehping Linda Chi, M.D. Paul L. Davis, M.D. Mark J. Dryden, M.D. Randy D. Ernst, M.D. Gregory Gladish, M.D. Sanjay Gupta, M.D. Revathy B. Iyer, M.D. Andras Konya, Ph.D. Vikas Kundra, M.D., Ph.D. Elizabeth A. Lano, M.D. David Madoff, M.D. Ravi Murthy, M.D. Chaan Ng, M.D. Bradley Sabloff, M.D. Joseph Steele, M.D. Janio Szklaruk, M.D., Ph.D. Eric P. Tamm, M.D. Mylene Truong, M.D. Michael J. Wallace, M.D. Wei Yang, M.D.

Assistant Professors

Beatriz Elena Adrada, M.D. Salmaan Ahmed, M.D. Judy Ahrar, M.D. Elsa Arribas, M.D. Rony Avritscher, M.D. Aparna Balachandran, M.D. Priya R. Bhosale, M.D. Yulia Bronstein, M.D. Selin Carkaci, M.D. Colleen Costelloe, M.D. James Matthew Debnam, M.D. Catherine Ellen Devine, M.D. Basak Erguvan Dogan, M.D. Nancy Elizabeth Fitzgerald, M.D. Nandita Guha-Thakurta, M.D. Tamara Miner Haygood, M.D., Ph.D. Harmeet Kaur, M.D. Vinodh A. Kumar, M.D. Michael Kwon, M.D., Ph.D. Deanna Lynn Lane, M.D. Ott Le, M.D. Kristen Lem, M.D. Huong Le-Petross, M.D. Armeen Mahvash, M.D. Leonardo Pimental Marcal, M.D. Stephen E. McRae, M.D. Rebecca Ashley Milam, M.D. Jane A. Onufer, M.D. Paul Oâ&#x20AC;&#x2122;Sullivan, M.D. Madhavi Patnana, M.D. Anjali Roy, M.D. Lumarie Santiago, M.D. Dawid Schellingerhout, M.D. Komal Shah, M.D. Tanya Stephens, M.D. Alda Lui Tam, M.D. Raghunandan Vikram, M.D. Chitra Viswanathan, M.D. Thinh Vu, M.D. Department of Experimental Diagnostic Imaging Professor and chair

Juri G. Gelovani, M.D., Ph.D. Professors

Chun Li, Ph.D. William Ping-Yiu Tong, Ph.D. Wai-Hoi Wong, Ph.D. David J. Yang, Ph.D. Associate Professors

Mian Alauddin, Ph.D. Hossain Baghaei, Ph.D. Victor Krasnykh, Ph.D. Hongdi Li, Ph.D. Assistant professor

Associate Professor

Mei Tian, M.D., Ph.D.

Assistant Professors

Amer M. Najjar, Ph.D.

Richard De La Garza, Ph.D. Yvette McLin, M.D. Anis Rashid, M.D.

Instructor

Continued ...

M. D. Anderson Faculty

Division of Internal Medicine Division head

Division of Diagnostic Imaging (continued)

Department of Imaging Physics Professor and chair

John D. Hazle, Ph.D. Professors

Dianna Cody, Ph.D. Edward F. Jackson, Ph.D. Chris C. Shaw, Ph.D. Richard Wendt III, Ph.D.

Robert F. Gagel, M.D. Department of Cardiology Professor and chair

Department of Gastroenterology, Hepatology and Nutrition

Professors

John R. Stroehlein, M.D.

Associate Professors

Manoop Bhutani, M.B.B.S. Robert Bresalier, M.D.

Edward T.H. Yeh, M.D.

Michael S. Ewer, M.D. Daniel J. Lenihan, M.D. Jean-Bernard Durand, M.D. Syed Wamique Yusuf, M.D.

Associate Professors

Luc Bidaut, Ph.D. Jingfei Ma, Ph.D. Osama Mawlawi, Ph.D. Tinsu Pan, Ph.D. Kathryn Peek, Ph.D. Yiping Shao, Ph.D. Konstanin V. Sokolov, Ph.D. Jihong Wang, Ph.D. Charles E. Willis, Ph.D.

Jinke Cheng, Ph.D. Iyad N. Daher, M.D. Cezar Iliescu, M.D. Aarif Y. Khakoo, M.D. Elie Mouhayar, M.D. Juan Carlos Plana, M.D. Sui Zhang, M.D., Ph.D.

Assistant Professors

Hong Dou, Ph.D.

James A. Bankson, Ph.D. Ping Hou, Ph.D. S. Cheenu Kappadath, Ph.D. John Rong, Ph.D. Jason Stafford, Ph.D. Xinming Liu, Ph.D. Instructor

Aaron Kyle Jones, Ph.D. Chao-Jen Lai, Ph.D. Linda T. Nieman, Ph.D. Department of Nuclear Medicine Professor and chair

Homer A. Macapinlac, M.D. Professors

Edmund Kim, M.D. Donald Podoloff, M.D. Franklin C. Wong, M.D., Ph.D., J.D. Associate Professors

Rodolfo F. Nunez, M.D. Eric Rohren, M.D.

Assistant Professors

Beth Chasen, M.D. Hubert Hsing Chuang, M.D., Ph.D.

Assistant Professors

Instructor

Department of Dermatology

Professor and chair Ad Interim Professors

Associate Professors

James Byrd, Ph.D. Marta Davila, M.D. Alexander A. Dekovich, M.D. Jeffrey Lee, M.D. Patrick M. Lynch, M.D., J.D. Dana Martin, M.D. William A. Ross, M.D. Mehnaz A. Shafi, M.D. Assistant Professors

Sushovan Guha, M.D., Ph.D. Nachman Mazurek, Ph.D. Shumei Song, M.D., Ph.D.

Professor and chair

Department of General Internal Medicine, Ambulatory Treatment and Emergency Care

Professors

Professor and chair

Ronald P. Rapini, M.D.

Madeleine Duvic, M.D. Sharon R. Hymes, M.D. Tri Nguyen, M.D. Associate Professors

Carol R. Drucker, M.D. Deborah Mac Farlane, M.D. Assistant Professors

Susan Chon, M.D. Ana M. Ciurea, M.D. Parul Hazarika, Ph.D. Michael R. Migden, M.D. Xiao Ni, M.D., Ph.D. Kenneth Y. Tsai, M.D., Ph.D. Chun-Lei Zhang, M.D., Ph.D. Department of Endocrine Neoplasia and Hormonal Disorders Professor and chair

Steven I. Sherman, M.D. Professors

Gilbert Cote, Ph.D. Victor R. Lavis, M.D. Associate Professors

Sara Peleg, Ph.D. Steven G. Waguespack, M.D. Assistant Professors

Naifa L. Busaidy, M.D. Jessica Devin, M.D. Mouhammed A. Habra, M.D. Mimi I-Nan Hu, M.D. Camilo Jimenez, M.D. Anita Kuo Ying, M.D.

Carmelita P. Escalante, M.D. Professors

Ellen F. Manzullo, M.D. Abdulla K. Salahudeen, M.D. Maria Suarez-Almazor, M.D., Ph.D. Robert Volk, Ph.D. Associate Professors

Shu-Wei Gao, M.D. Carmen E. Gonzalez, M.D. Tejpal Grover, M.D. Khanh Thi-Thuy Nguyen, M.D. Margaret B. Row, M.D. Sunil K. Sahai, M.D. Kathleen Anne Smalky, M.D. Sai-ching J. Yeung, M.D., Ph.D. Assistant Professors

Maria-Claudia Campagna, M.D. Patrick Chaftari, M.D. Niraj Choudhary, M.D. Maria T. Cruz Carreras, M.D. Marina George, M.D. Josiah Halm, M.D. Jerry Don Henderson, M.D. Holly M. Holmes, M.D. Jessica P. Hwang, M.D. Michael Kallen, Ph.D. Amit Lahoti, M.D. Wenli Liu, M.D. Huifang Lu, M.D., Ph.D. Mary Merkle, M.D. Jeong Oh, M.D. John T. Patlan, M.D. Terry W. Rice, M.D. Jean H. Tayar, M.D. Khanh D. Vu, M.D. Kirt Walker, M.D. Instructors

Gloria Iliescu, M.D. Dushyant Verma, M.D. Marieberta Vidal, M.D.

Department of Infectious Diseases, Infection Control and Employee Health Professor and chair

Issam I. Raad, M.D. Professors

Dimitrios P. Kontoyiannis, M.D. Kenneth V. Rolston, M.D. Associate Professors

Roy F. Chemaly, M.D. Elizabeth Conrad Frenzel, M.D. Ray Y. Hachem, M.D. Amar Safdar, M.D. Georgia A. Thomas, M.D. Assistant Professors

Javier A. Adachi, M.D. Bruno Palma Granwehr, M.D. Coralia N. Mihu, M.D. Victor Eduardo Mulanovich, M.D. Samuel Shelburne, M.D. Instructor

Anne-Marie P. Chaftari, M.D. Department of Pulmonary Medicine Professor and chair

Burton F. Dickey, M.D. Professors

Michael Kroll, M.D. Rodolfo C. Morice, M.D. Vickie R. Shannon, M.D. Associate Professors

Vahid Afshar-Kharghan, M.D. Georgie A. Eapen, M.D. Carlos Jimenez, M.D. David Ost, M.D. Michael J. Tuvim, Ph.D. Assistant Professors

Roberto Adachi, M.D. Diwakar Balachandran, M.D. Lara Bashoura, M.D. Christopher M. Evans, Ph.D. Scott Evans, M.D. Saadia Faiz, M.D. Instructor

Seyed Mirhassani Moghaddam, M.D. Department of Symptom Research Professor and chair

Charles Cleeland, Ph.D. Associate Professors

Karen O. Anderson, Ph.D. Xin Wang, M.D. Assistant Professors

Tito R. Mendoza, Ph.D. Guadalupe Palos, Dr.P.H. Qiuling Shi, Ph.D. Instructor

Loretta A. Williams, Ph.D.

M. D. Anderson Annual Report 2007-2008

Division of Pathology and Laboratory Medicine Division head

Stanley R. Hamilton, M.D. Department of Hematopathology Professor and chair

Jeffrey Medeiros, M.D. Professors

Carlos E. Bueso-Ramos, M.D., Ph.D. Richard J. Ford Jr., M.D., Ph.D. Yang O. Huh, M.D. Rajyalakshmi Luthra, Ph.D. John T. Manning, M.D. Timothy J. McDonnell, M.D., Ph.D. Associate Professors

Lynne Abruzzo, M.D., Ph.D. Hesham Amin, M.D. Sandy Chang, M.D., Ph.D. Daniel M. Jones, M.D., Ph.D. Hartmut Koeppen, M.D., Ph.D. Pei Lin, M.D. Roberto Miranda, M.D. James M. Reuben, Ph.D. Ellen J. Schlette, M.D. Assistant Professors

Jeffrey L. Jorgensen, M.D., Ph.D. Sergej Naumovich Konoplev, M.D., Ph.D. Bang-Ning Lee, Ph.D. Guohui Lu, M.D. Tariq Muzzafar, M.B.B.S. Mark J. Routbort, M.D., Ph.D. Rachel Lynn Sargent, M.D. Francisco Vega-Vazquez, M.D., Ph.D. Sa Wang, M.D. Cheng Yin, M.D., Ph.D. Mingjian James You, M.D., Ph.D.

Xin Han, M.D. Paul LaSala, M.D. Fernando Martinez, M.D. Luis E. Remus III, M.D., Ph.D. Kurt Clement Sizer, M.D. Xiaoping Sun, M.D., Ph.D. Department of Molecular Pathology Professor and chair

Ralph B. Arlinghaus, Ph.D. Professors

Eckhard Alt, M.D. Peter R. Gascoyne, Ph.D. Peng Huang, M.D., Ph.D. Macus T. Kuo, Ph.D. Sue-Hwa Lin, Ph.D. Associate Professors

Kun-Sang Chang, Ph.D. Jiale Dai, Ph.D. Subrata Sen, Ph.D. Yao-Hua Song, M.D., Ph.D. Assistant ProfessorS

Yu-Chen Lee, Ph.D. Sendurai Mani, Ph.D. Ajoy Kumar Samanta, Ph.D. Xiangcang Ye, Ph.D. Instructors

Xiaowen Bai, Ph.D. Hiroshi Katayama, Ph.D. Xiaohong Leng, Ph.D. Zhengdong Liang, M.D., Ph.D. Helene Pelicano, Ph.D. Jody V. Vykoukal, Ph.D. Department of Pathology Professor and chair

Instructor

Janet M. Bruner, M.D.

Department of Laboratory Medicine

Kenneth D. Aldape, M.D. Bogdan A. Czerniak, M.D., Ph.D. Michael T. Deavers, M.D. Adel K. El-Naggar, M.D., Ph.D. Harry L. Evans, M.D. Tina V. Fanning, M.D. Gregory N. Fuller, M.D., Ph.D. Stanley R. Hamilton, M.D. Ruth L. Katz, M.D. Anais Malpica, M.D. Jeanne M. Meis, M.D. Cesar Moran, M.D. Victor Prieto, M.D., Ph.D. Asif Rashid, M.D., Ph.D. Aysegul A. Sahin, M.D. Nour Sneige, M.D. Gregg A. Staerkel, M.D. William F. Symmans, M.D. Patricia Troncoso, M.D. Ignacio Ivan Wistuba, M.D. Wei Zhang, Ph.D.

Rajesh R. Singh, Ph.D.

Clinical professor and chair Ad Interim

Benjamin Lichtiger, M.D., Ph.D. Professors

Marcelo Fernandez-Vina, Ph.D. Herbert A. Fritsche Jr., Ph.D. Cheryl F. Hirsch-Ginsberg, M.D. Gregory May, Ph.D. Kathleen J. Sazama, M.D., J.D. Jeffrey J. Tarrand, M.D. Associate Professors

Pedro Cano, M.D. Xiang-Yang Han, M.D., Ph.D. Beverly Carol Handy, M.D. Aida B. Narvios, M.D. Assistant Professors

Su Chen, M.D., Ph.D.

Professors

Associate Professors

Susan Abraham, M.D. Constance Albarracin, M.D., Ph.D. Russell Broaddus, M.D., Ph.D. Nancy P. Caraway, M.D. Abdul Hafeez Diwan, M.D., Ph.D. Mary Elizabeth Edgerton, M.D., Ph.D. Michael Gilcrease, M.D., Ph.D. Savitri Krishnamurthy, M.D. Lauren A. Langford, M.D. Jinsong Liu, M.D., Ph.D. Lavinia P. Middleton, M.D. Austin K. Raymond, M.D. Pheroze Tamboli, M.D. Dongfeng Tan, M.D. Assistant Professors

Diana Bell, M.D. Alejandro Corvalan, M.D. Jonathan L. Curry, M.D. Elizabeth Dierksen Euscher, M.D. Yun Gong, M.D. Mahmoud Goodarzi, M.D. Charles Chuanhai Guo, M.D. Ming Guo, M.D. Lei Huo, M.D., Ph.D. Doina Ivan, M.D. Neda Kalhor, M.D. Alexander Lazar, M.D., Ph.D. Dipen Maheshbhai Maru, M.D. Erika Resetkova, M.D., Ph.D. Michael Warren Riben, M.D. Kanishka Sircar, M.D. John Stewart, M.D., Ph.D. Carlos Antonio Torres Cabala, M.D. Huamin Wang, M.D., Ph.D. Michelle Dianne Williams, M.D. Yun Wu, M.D., Ph.D. Gong Yang, Ph.D. Instructors

Krishna P. Bhat, Ph.D. Ping Ji, Ph.D. Maria Gabriela Raso, M.D. Andreana L. Rivera, M.D. Ying Wu, Ph.D.

Division of Pediatrics Division head

Eugenie S. Kleinerman, M.D. Department of Pediatrics Professor and chair

Eugenie S. Kleinerman, M.D. Professors

Peter Anderson, M.D., Ph.D. Joann L. Ater, M.D. Alan Fields, M.D. Cynthia E. Herzog, M.D. Bartlett D. Moore, Ph.D. Tribhawan S. Vats, M.D. Robert J. Wells, M.D. Johannes Wolff, M.D. Associate Professors

Joya Chandra, Ph.D. Laurence Cooper, M.D., Ph.D. Rodrigo Mejia, M.D. Regina Okhuysen-Cawley, M.D. Rhonda Robert, Ph.D. Michael E. Rytting, M.D. Laura L. Worth, M.D., Ph.D. Assistant Professors

Martha Askins, Ph.D. Jose Antonio Cortes, M.D. Anna Rachel Franklin, M.D. Vidya Gopalakrishnan, Ph.D. Dennis Hughes, M.D., Ph.D. Winston Huh, M.D. Susan Staba Kelly, M.D. Nadezhda V. Koshkina, Ph.D. Dean A. Lee, M.D., Ph.D. Cesar Augusto Nunez, M.D. Demetrios Petropoulos, M.D. Peter Eric Zage, M.D., Ph.D. Patrick A. Zweidler-McKay, M.D., Ph.D.

M. D. Anderson Faculty

Division of Radiation Oncology Division head

James D. Cox, M.D.

Division of Quantitative Sciences Division head

Donald Berry, Ph.D. Department of Bioinformatics and Computational Biology Professor and chair

John N. Weinstein, M.D., Ph.D. Professors

Jonas Silva Almeida, Ph.D. Shoudan Liang, Ph.D. Susan L. Tucker, Ph.D. Associate Professors

Keith A. Baggerly, Ph.D. Bradley McIntosh Broom, Ph.D. Kevin R. Coombes, Ph.D. Mandri N. Obeyesekere, Ph.D. Lynn H. Vogel, Ph.D. Assistant Professors

Yuan Ji, Ph.D. Li Zhang, Ph.D. Ming Zhang, Ph.D. Instructors

Department of Experimental Radiation Oncology Professor and chair Ad Interim

Raymond E. Meyn Jr., Ph.D. Professors

Khandan Keyomarsi, Ph.D. Marvin L. Meistrich, Ph.D. Luka Milas, M.D., Ph.D. Elizabeth L. Travis, Ph.D. Associate Professors

Lei Li, Ph.D. Kathryn A. Mason, M.S.

Assistant Professors

Said Akli, Ph.D. Anupama Munshi, Ph.D. Uma Raju, Ph.D. Gunapala Shetty, Ph.D. Rozita Yarmand, Ph.D. Instructors

Ekem T. Efuet, Ph.D. Yuhui Yuan, M.D., Ph.D.

Romesh C. Stanislaus, Ph.D. Jing Wang, Ph.D.

Department of Radiation Oncology

Department of Biostatistics

Thomas A. Buchholz, M.D.

M. Kara Bucci, M.D. Rex Min Cheung, M.D., Ph.D. Seungtaek Choi, M.D. Gregory Chronowski, M.D.* Bouthaina Shbib Dabaja, M.D. Prajnan Das, M.D. Steven Jay Frank, M.D. Ramesh Gopal, M.D., Ph.D. Beverly Ashleigh Guadagnolo, M.D. Melenda Jeter, M.D. Ann H. Klopp, M.D., Ph.D. Sunil Krishnan, M.D. Mary McAleer, M.D., Ph.D. Quynh Nguyen, M.D. Julia Linda Oh, M.D. Christopher E. Pelloski, M.D. Valerie Klairisa Reed, M.D. Pamela J. Schlembach, M.D.* David L. Schwartz, M.D. Samir Vasant Sejpal, M.D.* Shalin Jyotindra Shah, M.D.* Erik Philip Sulman, M.D., Ph.D. Welela Tereffe, M.D. James Welsh, M.D. Wendy Woodward, M.D., Ph.D. Tse-Kuan Yu, M.D., Ph.D. *Member of M. D. Anderson Physicians Network

Professor and chair

Donald Berry, Ph.D. Professors

Edward N. Atkinson, Ph.D. Scott B. Cantor, Ph.D. Kim-Anh Do, Ph.D. Linda S. Elting, Dr.P.H. Kenneth R. Hess, Ph.D. Valen E. Johnson, Ph.D. Jiun-Kae Jack Lee, Ph.D. Peter Mueller, Ph.D. Gary L. Rosner, Sc.D. Yu Shen, Ph.D. Peter F. Thall, Ph.D. Associate Professors

Benjamin Nebiyou Bekele, Ph.D. Xuelin Huang, Ph.D. Jeffrey Morris, Ph.D. Ya-Chen Shih, Ph.D. Guosheng Yin, Ph.D. Assistant Professors

Veerabhadran Baladandayuthapani, Ph.D. Jianhua Hu, Ph.D. Yisheng Li, Ph.D. Ying Yuan, Ph.D. Instructor

Richard J. Swartz, Ph.D.

Professors

Kie-Kian Ang, M.D., Ph.D. Patricia J. Eifel, M.D. Adam S. Garden, M.D. Ritsuko Komaki, M.D. Deborah A. Kuban, M.D. William H. Morrison, M.D. David I. Rosenthal, M.D. Eric A. Strom, M.D. Shiao Y. Woo, M.D. Gunar K. Zagars, M.D. Associate Professors

Matthew T. Ballo, M.D.* Elizabeth S. Bloom, M.D.* Eric L. Chang, M.D. Joe Y. Chang, M.D., Ph.D. Christopher Crane, M.D. Marc E. Delclos, M.D. Thomas M. Guerrero, M.D., Ph.D. Anuja Jhingran, M.D. Andrew K. Lee, M.D. Zhongxing Liao, M.D. Anita Mahajan, M.D. Michael Oâ&#x20AC;&#x2122;Reilly, M.D. George H. Perkins, M.D. Assistant Professors

Isidora Arzu, M.D., Ph.D.*

Department of Radiation Physics Professor and chair

Radhe Mohan, Ph.D. Professors

Sam Beddar, Ph.D. Michael Gillin, Ph.D. Geoffrey Ibbott, Ph.D. Mary K. Martel, Ph.D. Almon S. Shiu, Ph.D. Alfred R. Smith, Ph.D. George Starkschall, Ph.D. Marilyn Stovall, Ph.D. Xiaorong Ronald Zhu, Ph.D. Associate Professors

Lei Dong, Ph.D. David S. Followill, Ph.D. Karl L. Prado, Ph.D. Narayan Sahoo, Ph.D. Mohammad Salehpour, Ph.D. Kazumichi Suzuki, Ph.D. Ramesh C. Tailor, Ph.D. Assistant Professors

Bijan Arjomandy, Ph.D. Peter A. Balter, Ph.D. Martin Bues, Ph.D. Kent A. Gifford, Ph.D.* Rebecca Maureen Howell, Ph.D.

Sandeep Hunjan, Ph.D. Rajat J. Kudchadker, Ph.D. Dershan Luo, Ph.D. Dragan Mirkovic, Ph.D. Firas Mourtada, Ph.D. Wayne D. Newhauser, Ph.D. Jerimy Clifford Polf, Ph.D. Uwe Titt, Ph.D. Oleg N. Vassiliev, Ph.D. Sastry Vedam, Ph.D. Milos Vicic, Ph.D. Xiaochun Wang, Ph.D. James N. Yang, Ph.D. Sean X. Zhang, Ph.D. Xiaodong Zhang, Ph.D. Instructors

Tina Marie Briere, Ph.D. George Ciangaru, Ph.D. Weiliang Du, Ph.D. Song Gao, Ph.D. Stephen F. Kry, Ph.D. Christopher Lee Nelson, Ph.D.* Congjun Wang, Ph.D. He Wang, Ph.D. *Member of M. D. Anderson Physicians Network

M. D. Anderson Annual Report 2007-2008

Division of Surgery Division head

Raphael E. Pollock, M.D., Ph.D.

David M. Gershenson, M.D.

Michael Elliot Kupferman, M.D. Stephen Yenzen Lai, M.D., Ph.D. Guojun Li, M.D., Ph.D. Ge Zhou, Ph.D.

Professors

Instructor

Department of Gynecologic Oncology Professor and chair

Michael W. Bevers, M.D. Diane C. Bodurka, M.D. Thomas W. Burke, M.D. Robert Coleman, M.D. Michele Follen, M.D., Ph.D. Charles F. Levenback, M.D. Karen H. Lu, M.D. Samuel Mok, Ph.D. Anil K. Sood, M.D. George Stancel, Ph.D. Judith K. Wolf, M.D.

Tongxin Xie, M.D., Ph.D.

Associate Professors

Oliver Bogler, Ph.D. Amy B. Heimberger, M.D. Suyun Huang, Ph.D. Sujit S. Prabhu, M.D. Laurence D. Rhines, M.D. Dima Suki, Ph.D. Jeffrey Weinberg, M.D.

Andrea Milbourne, M.D. Pedro Tomas Ramirez, M.D. Lois M. Ramondetta, M.D. Helen E. Rhodes, M.D. Rosemarie Schmandt, Ph.D. Judith Ann Smith, Pharm.D. Kwong K. Wong, Ph.D. Assistant Professors

Jubilee Brown, M.D. Michael Frumovitz, M.D. Elizabeth R. Keeler, M.D. Charles N. Landen, M.D. Kathleen M. Schmeler, M.D. Pamela Therese Soliman, M.D. Charlotte C. Sun, Dr.P.H. Wei Hu, M.D., Ph.D. Department of Head and Neck Surgery Professor and chair

Randal S. Weber, M.D. Professors

Mark S. Chambers, D.M.D. Gary L. Clayman, M.D., D.D.S., D.M.D. Eduardo M. Diaz Jr., M.D. Ann Marie Gillenwater, M.D. Ehab Y. Hanna, M.D. Rhonda F. Jacob, D.D.S. Jack W. Martin, D.D.S. Jeffrey N. Myers, M.D., Ph.D. Jade S. Schiffman, M.D. Bela B. Toth, D.D.S. Associate Professors

Bita Esmaeli, M.D. Paul W. Gidley, M.D. Dan S. Gombos, M.D. Stella K. Kim, M.D. Jan S. Lewin, Ph.D. Erich M. Sturgis, M.D. Xiangwei Wu, Ph.D.

Assistant Professors

Carlos Caulin, Ph.D. Mitchell J. Frederick, Ph.D. Amy Clark Hessel, M.D. Theresa Maria Hofstede, D.D.S. Floyd Holsinger, M.D.

Department of Neurosurgery Professor and chair

Raymond E. Sawaya, M.D. Professors

Franco DeMonte, M.D. Frederick F. Lang Jr., M.D. Ian E. McCutcheon, M.D. Associate Professors

Assistant Professors

Syed S. Azeem, M.D. Nicholas B. Levine, M.D. Anshu Bagga Mathur, Ph.D. Ganesh Rao, M.D. Instructors

Anupama Edward Gururaj, Ph.D. Khatri Latha, Ph.D. Jun Wei, Ph.D. Department of Plastic Surgery Professor and chair

Geoffrey L. Robb, M.D. Professors

Elisabeth K. Beahm, M.D. Charles E. Butler, M.D. David W. Chang, M.D. Greg P. Reece, M.D. Associate Professors

Steven Kronowitz, M.D. Scott Oates, M.D. Roman Skoracki, M.D. Peirong Yu, M.D.

Assistant Professors

Donald P. Baumann, M.D. Melissa Ann Crosby, M.D. Matthew M. Hanasono, M.D. Anshu Bagga Mathur, Ph.D. Justin Michael Sacks, M.D. Mark Timothy Villa, M.D. Department of Surgical Oncology Professor and chair

Raphael E. Pollock, M.D., Ph.D. Professor

Paul J. Chiao, Ph.D. Steven A. Curley, M.D.

Lee M. Ellis, M.D. Barry W. Feig, M.D. Jeffrey E. Gershenwald, M.D. Kelly K. Hunt, M.D. Henry Mark Kuerer, M.D., Ph.D. Jeffrey Lee, M.D. Paul F. Mansfield, M.D. Peter W. Pisters, M.D. Miguel A. Rodriguez-Bigas, M.D. Merrick I. Ross, M.D. S. Eva Singletary, M.D. John M. Skibber, M.D. Jean Nicolas Vauthey, M.D. Associate Professors

Eddie K. Abdalla, M.D. Gildy Babiera, M.D. Ervin B. Brown, M.D. Janice Nicole Cormier, M.D. Jason B. Fleming, M.D. Valerae O. Lewis, M.D. Patrick P. Lin, M.D. Anthony Lucci, M.D. Funda Meric-Bernstam, M.D. Nancy Dugal Perrier, M.D. Assistant Professors

Isabelle Bedrosian, M.D. Christopher P. Cannon, M.D. George J. Chang, M.D. Paul Cherukuri, Ph.D. Elizabeth Gardner Grubbs, M.D. Andrea Hayes-Jordan, M.D. Rosa Frances Hwang, M.D. Laura Ann Lambert, M.D. Elizabeth Ann Mittendorf, M.D. Balraj Singh, Ph.D. Xin Wang, Ph.D. Yan Xing, Ph.D. Instructors

Zhongkui Li, Ph.D. Jianhua Ling, Ph.D. Heping Liu, Ph.D. Suizhao Wang, M.D., Ph.D. Department of Thoracic and Cardiovascular Surgery Professor and chair

Stephen G. Swisher, M.D. Professors

Reza John Mehran, M.D. Jack A. Roth, M.D. Garrett L. Walsh, M.D. Associate Professors

Bingliang Fang, M.D., Ph.D. Wayne L. Hofstetter, M.D. Lin Ji, Ph.D. Rajagopal Ramesh, Ph.D. David C. Rice, M.D. Ara A. Vaporciyan, M.D. Assistant Professors

Instructors

Wei Guo, M.D., Ph.D. Matthew Allen Steliga, M.D. Department of Urology Professor and chair

Colin P.N. Dinney, M.D. Professors

Joseph N. Corriere Jr., M.D. H. Barton Grossman, M.D. David J. McConkey, Ph.D. Curtis A. Pettaway, M.D. Louis L. Pisters, M.D. Associate Professors

Ashish Kamat, M.D. Surena Matin, M.D. Ouida Lenaine Westney, M.D. Christopher G. Wood, M.D. Assistant Professors

Liana Adam, M.D., Ph.D. John W. Davis, M.D. John F. Ward, M.D. Instructors

Woonyoung Choi, Ph.D. Aditi Das, Ph.D. Loleta D. Harris, Ph.D.

School of Health Professions M. D. Andersonâ&#x20AC;&#x2122;s School of Health Professions educates medical support professionals who are in high demand across the United States, awarding bachelorâ&#x20AC;&#x2122;s degrees and certificates in eight allied health programs. Dean

Michael J. Ahearn, Ph.D. Assistant professors

Shaun T. Caldwell, M.S. Melissa J. Chapman, M.Ed. Hazel V. Dalton, M.S. Brandy A. Greenhill, M.S. Stephanie Ann Hamilton, D.Ed. Vicki L. Hopwood, M.S. Peter C. Hu, Ph.D. Patrick Lennon, Ph.D. Karen J. McClure, Ph.D. Nanci L. Saurdiff, M.Ed. Instructors

Mark A. Bailey, M.A. Mahsa Dehghanpour, M.S. Jun Gu, M.D. Catherine M. Murphy, M.S. Suzieann M. Richards-Bass, M.Ed. Megan L. Trad, M.S.

Arlene M. Correa, Ph.D. Abujiang Pataer, M.D., Ph.D. 67

M. D. Anderson Faculty

Basic science departments External Advisory Board

Department of Biochemistry and Molecular Biology

Instructors

M. D. Anderson’s External Advisory Board is composed of highly regarded scientific advisors who consult with M. D. Anderson faculty leaders on specific programmatic research initiatives. Carolyn Aldigé Prevent Cancer Foundation Alexandria, Va.

James O. Armitage, M.D.

William G. Nelson, M.D., Ph.D. Johns Hopkins University School of Medicine

University of Nebraska

Eric N. Olson, Ph.D.

Andreas D. Baxevanis, Ph.D.

The University of Texas Southwestern Medical Center at Dallas

National Human Genome Research Institute National Institutes of Health

Elizabeth Blackburn, Ph.D. University of California, San Francisco

Paul A. Bunn Jr., M.D. University of Colorado Cancer Center

Richard Caprioli, Ph.D. Vanderbilt University

Susan Curry, Ph.D.

Bert O’Malley, M.D. Baylor College of Medicine

Richard J. O’Reilly, M.D. Memorial Sloan-Kettering Cancer Center

Franklyn Prendergast, M.D., Ph.D. Mayo Clinic

Edward Sausville, M.D., Ph.D.

University of Iowa

University of Maryland Medical System

Andrew Dannenberg, M.D.

Richard Schilsky, M.D.

Weill Cornell Cancer Center

The University of Chicago

Nancy E. Davidson, M.D.

Thomas A. Sellers, Ph.D., M.P.H.

Johns Hopkins University School of Medicine

Sarah S. Donaldson, M.D. Stanford Cancer Center

Norman R. Drinkwater, Ph.D. University of WisconsinMadison

Steven N. Goodman, M.D.

University of California, San Francisco

Jeffrey M. Trent, Ph.D.

Harvard Medical School

H. Kim Lyerly, M.D.

Translational Genomics Research Institute Phoenix, Ariz.

Geoffrey M. Wahl, Ph.D. Salk Institute

Richard L. Wahl, M.D. Johns Hopkins University

Marcy Waldinger, M.H.S.A.

Joan Massague, Ph.D.

University of Michigan Comprehensive Cancer Center

Harold Moses, M.D. Vanderbilt-Ingram Cancer Center

Assistant Professors

Xiaomin Chen, Ph.D. Michael J. Galko, Ph.D. Jayanthi Gudikote, Ph.D. Raymond H. Jacobson, Ph.D. Todd M. Link, Ph.D. Marek Napierala, Ph.D. Xiaobing Shi, Ph.D. Shinako Takada, Ph.D. Instructors

Professor and chair

John DiGiovanni, Ph.D. Professors

Claudio M. Aldaz, M.D. Susan M. Fischer, Ph.D. David G. Johnson, Ph.D. Donna Frances Kusewitt, D.V.M., Ph.D. Michael C. MacLeod, Ph.D. David L. Mitchell, Ph.D. Rodney S. Nairn, Ph.D. Ellen R. Richie, Ph.D. Cheryl L. Walker, Ph.D. Paul K. Wong, Ph.D. Richard Wood, Ph.D. Associate Professors

Joe M. Angel, Ph.D. Mark T. Bedford, Ph.D. Fernando Jose Benavides, D.V.M., Ph.D. Lezlee G. Coghlan, D.V.M. Robin Fuchs-Young, Ph.D. Irma B. Gimenez-Conti, D.D.S., Ph.D. Kaoru Kiguchi, M.D., Ph.D. Jianjun Shen, Ph.D. Xuetong Shen, Ph.D. Dean G. Tang, Ph.D. Karen M. Vasquez, Ph.D. Assistant Professors

Joyce E. Rundhaug, Ph.D. Mingshan Yan, M.D. Instructors

Professor and chair Ad Interim

Lee M. Ellis, M.D. Professors

Menashe Bar Eli, Ph.D. Douglas D. Boyd, Ph.D. Dominic Fan, Ph.D. Isaiah J. Fidler, D.V.M., Ph.D. Craig Logsdon, Ph.D. Alan J. Schroit, Ph.D. Associate Professors

Duke Comprehensive Cancer Center

Memorial Sloan-Kettering Cancer Center

Associate Professors

Andreas Bergmann, Ph.D. Yasuhide Furuta, Ph.D. Georg Halder, Ph.D. Randy L. Johnson, Ph.D. Jan Parker-Thornburg, Ph.D. Maria Schumacher, Ph.D.

Friends of Cancer Research Arlington, Va.

University of Pennsylvania Health System

David N. Louis, M.D.

ProfessorS

Michelle Barton, Ph.D. Richard Brennan, Ph.D. Sharon R. Dent, Ph.D. John E. Ladbury, Ph.D. Pierre D. McCrea, Ph.D. Miles F. Wilkinson, Ph.D.

Department of Cancer Biology

Joe W. Gray, Ph.D.

Department of Carcinogenesis

William H. Klein, Ph.D.

Ellen Sigal, Ph.D.

Craig B. Thompson, M.D.

University of California, San Diego

Professor and chair

Johns Hopkins University

David Sidransky, M.D.

Johns Hopkins University

Richard D. Kolodner, Ph.D.

Seung Kim, Ph.D. Vladislava Melnikova, Ph.D. Vijaya Ramachandran, Ph.D.

Anjana Bhardwaj, Ph.D. Jang-Hyeon Cho, Ph.D. Sao Jiralerspong, M.D., Ph.D. Takae Kiyama, Ph.D. Chai-An Mao, Ph.D. Kate Juliet Newberry, Ph.D.

H. Lee Moffitt Cancer Center and Research Institute

David G. Menter, Ph.D. Kenji Yokoi, M.D., Ph.D.

Sun Kim, M.D., Ph.D. Janet E. Price, Ph.D. Zhengxin Wang, Ph.D.

Assistant Professors

Krishnakumar Balasubramanian, Ph.D. Dina Chelouche Lev, M.D. Vijaykumar Holla, Ph.D. Baoan Ji, M.D., Ph.D. Robert Langley, Ph.D. Joseph McCarty, Ph.D.

Erika L. Abel, Ph.D. Thomas R. Berton, Ph.D. Donghang Cheng, Ph.D. Okkyung Rho, Ph.D. Virginia L. Scofield, Ph.D. Guliang Wang, M.D., Ph.D. Department of Genetics

Professor and chair

Guillermina Lozano, Ph.D. Professors

Richard R. Behringer, Ph.D. Benoit deCrombrugghe, M.D. Vicki D. Huff, Ph.D. Ann M. Killary, Ph.D. Randy J. Legerski, Ph.D. Sadhan Majumder, Ph.D. Louise C. Strong, M.D. Hideyo Yasuda, Ph.D.

M. D. Anderson Annual Report 2007-2008

Associate Professors

Sandy Chang, M.D., Ph.D. Mini Kapoor, Ph.D. Ralf Krahe, Ph.D. Angabin Matin, Ph.D. William W. Mattox, Ph.D. Lalitha Nagarajan, Ph.D. Jill Schumacher, Ph.D. Assistant Professors

Department of Molecular and Cellular Oncology

Professor and chair

Yuko Akiyama, M.D. Linda L. Bachinski, Ph.D. Nanyue Chen, M.D., Ph.D. Yibin Deng, Ph.D. Asha S. Multani, Ph.D. Bin Wang, Ph.D. Shunbin Xiong, Ph.D.

Mien-Chie Hung, Ph.D.

Instructors

Mong-Hong Lee, Ph.D. Xin Lin, Ph.D. Michael W. Van Dyke, Ph.D.

Shamima Akhter, Ph.D. Seetharaman Balasenthil, Ph.D. June Li, Ph.D. Krishna Sinha, Ph.D. Sonali Sonnylal, Ph.D. Young-Ah Suh, Ph.D. Yang Wang, M.D., Ph.D. Marzena Wojciechowska, Ph.D. Hao Zhang, Ph.D. Xiaoshan Zhang, M.D., Ph.D. Department of Immunology

Associate Professors

Bruce J. Bernacky, D.V.M. Alan G. Brady, D.V.M. Gary L. Johanning, Ph.D. Mark J. McArthur, D.V.M. Pramod N. Nehete, Ph.D. Julio Cesar Ruiz, D.V.M. Steven J. Schapiro, Ph.D.

Feng Wang-Johanning, M.D., Ph.D. Lawrence E. Williams, Ph.D. Assistant Professors

Kirstin F. Barnhart, D.V.M. Stephanie J. Buchl, D.V.M. Patrick Hanley, D.V.M

Provided by Faculty Academic Affairs, the faculty list reflects individuals with full-time faculty appointments. List as of February 2009.

Professors

Jim Klostergaard, Ph.D. Stephen P. Tomasovic, Ph.D. Dihua Yu, M.D., Ph.D. Associate Professors

Assistant Professors

Elsa Renee Flores, Ph.D. Hui-Kuan Lin, Ph.D. Suresh K. Rayala, Ph.D. Dos Sarbassov, Ph.D. Weiya Xia, M.D. Hirohito Yamaguchi, Ph.D. Instructors

Qing-Qing Ding, Ph.D. Yongkun Wei, M.D., Ph.D. Department of Veterinary Medicine and Surgery

Administration Office of the President

John Mendelsohn, M.D.

Vice president for development

Adrienne C. Lang

Stephen C. Stuyck

Vice president for center programs Vice president for governmental relations

Office of the Executive Vice President and Physician-in-Chief

Thomas W. Burke, M.D.

Lewis E. Foxhall, M.D.

Executive vice president and physician-in-chief

Vice president for health policy

Gerard J. Colman

Vice president and head, Division of Pharmacy

Senior vice president and chief of clinical operations

John Bingham Vice president for process improvement Vice president for global clinical programs

Thomas W. Feeley, M.D.

Yong-Jun Liu, M.D., Ph.D.

Vice president for public affairs

Mark A. Moreno

Eduardo M. Diaz Jr., M.D. Professor and chair

Patrick B. Mulvey

President

Joel D. Lajeunesse

Alma Rodriguez, M.D. Vice president for medical affairs

Barbara L. Summers, Ph.D. Vice president and chief nursing officer

Frank R. Tortorella, J.D. Vice president for clinical support services

Vice president for medical operations

Professors

Chen Dong, Ph.D. Bradley W. McIntyre, Ph.D. Jagannadha K. Sastry, Ph.D. Shao-Cong Sun, Ph.D. Stephen E. Ullrich, Ph.D. Associate Professors

Michel Gilliet, M.D. Hector Martinez-Valdez, M.D., Ph.D. Stephanie S. Watowich, Ph.D. Assistant Professors

Wei Cao, Ph.D. Roza Nurieva, Ph.D. F. Xiao-Feng Qin, Ph.D. Kimberly Schluns, Ph.D. Kenneth Y. Tsai, M.D., Ph.D. Tomasz Zal, Ph.D. Chengming Zhu, Ph.D. Instructors

Laura Bover, Ph.D. Valeria Facchinetti, Ph.D. Shino Hanabuchi, Ph.D. Natalia Martin Orozco, Ph.D. Eulogia Roman, Ph.D. Kui Voo, Ph.D. Xuexian Yang, Ph.D. Yongliang Zhang, Ph.D. Zhiqiang Zhang, Ph.D.

Associate Professor and chair

Peggy T. Tinkey, D.V.M. Professor

Sherry Klumpp, D.V.M. Associate Professors

Agatha Borne, D.V.M., Ph.D. David Wayne Brammer, D.V.M. Suzanne Craig, D.V.M. Assistant Professors

Mihai Gagea Iurascu, D.V.M. Katherine A. Naff, D.V.M. Rajesh Uthamanthil, D.V.M., Ph.D. Instructor

Cynthia R. Lockworth, D.V.M. Department of Veterinary Sciences

Office of the Provost and Executive Vice President

Raymond N. DuBois, M.D., Ph.D.

Ernest T. Hawk, M.D.

Provost and executive vice president

Vice president and head, Division of Cancer Prevention and Population Sciences

Robert C. Bast Jr., M.D. Vice president for translational research

Karen K. Fields, M.D. Vice president for global academic programs

Professors

Senior vice president for academic affairs

Matthew A. Masek, J.D.

Executive vice president and chief business officer

Vice president and chief legal officer

R. Dan Fontaine, J.D.

Vice president and chief financial officer

Senior vice president for business affairs

Christopher C. Capelli, M.D. Vice president for technology transfer

Harry R. Gibbs, M.D.

Wallace Baze, D.V.M., Ph.D. William C. Satterfield, D.V.M.

Stephen P. Tomasovic, Ph.D.

Office of Business and Regulatory Affairs

Vice president for operations and facilities management

Professor and chair

Vice president for clinical research

Leon J. Leach

William A. Daigneau

Christian Abee, D.V.M.

Maurie Markman, M.D.

Vice president for institutional diversity

M. Mitchell Latinkic Vice president for global business development

Dwain Morris Jessica L. Quinn, J.D. Vice president and chief compliance officer

John A. Tietjen Vice president for patient financial services

Shibu Varghese Vice president for human resources

Lynn H. Vogel, Ph.D. Vice president and chief information officer

The University Cancer Foundation Board of Visitors

2008-2009

The University Cancer Foundation Board of Visitors is an appointed volunteer board of individuals who are committed to helping M. D. Anderson achieve its mission of eliminating cancer. Board programs emphasize private fund development, public relations and outreach on behalf of the institution.

Ernest H. Cockrell Chair

Nancy B. Loeffler Chair-elect

Ali A. Saberioon Vice chair

Strategic Advisory Committee

Chairman’s Committee

Life members

Mr. Leon Davis

Chair

Mrs. Barbara Bush

Mr. John H. Duncan, Sr.

Chair

Mr. Ernest H. Cockrell

The Honorable George H. W. Bush

Mr. Dillon J. Ferguson

Mr. Edwin L. Cox

Mr. Jerry E. Finger

Mr. Paul R. Haas*

Mr. George E. Foreman

Dr. Charles A. LeMaistre

Mr. Gibson Gayle, Jr.

Mrs. Julia Jones Matthews

Mr. Wayne Gibbens

Mr. L. Lowry Mays

Mr. Gary F. Gibson

Mr. Ernest H. Cockrell Members

Mrs. Judy Ley Allen Mr. Philip J. Burguieres

Chair-elect

Mrs. Nancy B. Loeffler Advance Team

Mr. Don M. Woo

Mr. Terry M. Giles

Bylaws

Mr. Red McCombs

Ms. Frances E. Ginsburg

Mr. David M. Grimes II

The Hon. Linda L. Addison

Mr. George P. Mitchell

Mr. F. O’Neil Griffin

Mr. W. A. “Tex” Moncrief, Jr.

Ms. Lyda Hill

The Honorable Robert A. Mosbacher, Sr.

Mr. Forrest E. Hoglund

Mr. T. Boone Pickens

Mr. D. Alter Holand

Mr. Ben A. Guill Mr. Melvyn N. Klein Mrs. Nancy B. Loeffler

Community relations

Ms. Regina J. Rogers Mr. Steven H. Wasserman

Mr. Joseph D. Jamail

Mr. Harry J. Longwell Mr. Rodney H. Margolis Mr. Steven L. Miller Mr. Ali A. Saberioon Mr. Marc J. Shapiro Mr. Charles W. Tate Mr. Robert B. Tudor III

Development

Mr. Gus H. Comiskey Jr.

Senior members

Mrs. Kit Moncrief

Mr. John D. Alexander, Jr. The Honorable John S. Anderson

Events

Mrs. Joan Schnitzer Levy Mrs. Beth Sanders Moore

Mr. Edward Azar The Honorable James A. Baker III The Honorable Dolph Briscoe, Jr.

Government relations

Mr. Roy A. Butler

Mr. Wayne Gibbens

Mr. Charles Butt

Mr. Ned S. Holmes Mrs. Glenda R. Kane Membership and board development

Mr. Ali A. Saberioon

Marc J. Shapiro Past chair

Pastor Kirbyjon H. Caldwell Mr. William E. Carl Mrs. Jane M. Cizik Mr. Rufus Cormier, Jr. Mr. James D. Dannenbaum

*Deceased

Mr. James F. Justiss, Jr. Mrs. Glenda R. Kane Mr. Melvyn N. Klein Mr. R. Bruce LaBoon Mrs. Marty V. Leonard Mr. Max Levit Mr. Michael R. Levy Mr. Harry J. Longwell Mr. Jeff B. Love Mrs. Margaret Love Mr. Kade L. Matthews Mrs. Mary Anne McCloud Mr. Michael D. McKinnon Mrs. Sonceria Messiah-Jiles

M. D. Anderson Annual Report 2007-2008

Mr. Randall Meyer

Mrs. Mary V. Lester

Mr. Ned S. Holmes

Mr. Rick J. Calhoon

Mr. Steven L. Miller

Mrs. Nancy B. Loeffler

Mrs. Sydney Huffines

Mr. Clarence P. Cazalot, Jr.

Mrs. Kit Moncrief

The Honorable Thomas F. McLarty III

Mr. Woody L. Hunt

Dr. Nancy T. Chang

Mr. Charles E. Hurwitz

Mrs. Nadine Craddick

Mr. Dennis E. Nixon

Mrs. Judith Jaynes

Mrs. Jan E. Duncan

Mrs. Jan R. Pickens

Mr. Gregory A. Kozmetsky

Mrs. Elizabeth G. Epley

Mr. Jack P. Randall

Mr. Eric S. Lane

Mr. Sheldon R. Erikson

Mrs. Nancy M. Seliger

Mrs. Elyse Lanier

The Honorable Donald L. Evans

Mr. Marc J. Shapiro

Mr. C. Berdon Lawrence

Mr. G. Steven Farris

Mr. Matthew R. Simmons

Mrs. Joan Schnitzer Levy

Mr. William B. Finneran

Mr. J. Michael Solar

Mrs. Marlene A. Malek

Mrs. Patsy S. Fourticq

Mr. J. Virgil Waggoner

Mr. Rodney H. Margolis

Mr. Michael E. Frazier

Mr. Steven H. Wasserman

Mr. Jack L. Martin

Mr. Thomas S. Glanville

Mrs. Marie F. Wise

Mrs. Stacie McDavid

Mr. Steven L. Gordon

Mr. Melvyn L. Wolff

Mr. E. Scott Mead

Mr. Richard W. Gray III

Mr. Allen A. Meyer

Mr. Felo Guerra

Mr. Henry G. Musselman Mr. W. Robert Nichols III Mr. C. Lamar Norsworthy III Mrs. Kay M. Onstead Mr. B. M. Rankin, Jr. Ms. Regina J. Rogers Mr. Federico Sada Mrs. Peggy Sewell Mr. Joseph F. Shaughnessy Mr. Charles M. Simmons Mr. Robert I. Small Mr. Gerald B. Smith Mrs. Janice Thomas Vinson Dr. Richard E. Wainerdi

Members

Mr. C. John Miller

Ms. Patricia Hewlett

Mr. W. Temple Webber, Jr.

Mrs. Judy Ley Allen

Mr. Richard W. Mithoff, Jr.

Mr. Tom Johnson

Mrs. Margaret Alkek Williams

Mr. Paul F. Barnhart, Jr.

Mr. William A. Monteleone, Jr.

Mrs. Julie Kyte

Mrs. Isabel B. Wilson

Mr. Michael G. Bartolotta

Mrs. Beth Sanders Moore

Mrs. Neda Ladjevardian

Mr. Lawrence E. Bathgate II

Mr. James J. Mulva

Mr. Stephen A. Lasher

Members-at-large

Mr. Jack S. Blanton, Sr.

Mr. David G. Nance

Mrs. Helen H. Laughery

Mr. Richard C. Adkerson

Mr. Giorgio Borlenghi

Mr. Paul F. Oreffice

Mr. Homer L. Luther, Jr.

Mr. Stanford J. Alexander

Mr. John Baxter Brinkmann

Mr. Patrick C. Oxford

Mrs. Linda McCaul

Mr. Robert J. Allison, Jr.

Mr. B. Daryl Bristow

Mrs. Nelda Cain Pickens

Mr. R. Drayton McLane, Jr.

Mr. Moshe Azoulay

Mr. Kyle C. Brooks

Mr. William E. Rosenthal

Mr. William Millard

Mrs. Sally B. Berry

Mr. Ernest H. Cockrell

Mrs. Helen Lho Ryu

Mr. Lewis J. Moorman III

Mr. Joel Brochstein

Mrs. Anne P. Connally

Mr. Ali A. Saberioon

Mr. Marvin Odum

Mr. Philip J. Burguieres

Mr. John B. Connally III

Mr. Andrew E. Sabin

Mrs. Pamela K. Onstead

Mr. Gus H. Comiskey, Jr.

Mr. Phil D. Conway

Mr. Lester H. Smith

Mrs. Mildred M. Oppenheimer

Mrs. Shirley Coskey

Mrs. Charline Dauphin

Mr. H. Leighton Steward

Mrs. Roseann Park

Mr. William J. DorĂŠ, Sr.

Mrs. Myrna J. Deckert

Mr. Stephen D. Susman

Mr. Gene Rainbolt

Mr. S. Stacy Eastland

Mrs. Linnet F. Deily

Mr. Charles W. Tate

Mr. Christopher Sarofim

Mr. Randy R. Engstrom

Mrs. Lorraine Dell

Mr. Robert B. Tudor III

Dr. Thomas Seitz

Mr. Stephen L. Feinberg

Mr. Ben A. Donnell

Mrs. Cheryl Lockton Williams

Mr. Walter J. Smith

Mr. Alan D. Feld

Mr. John F. Fort III

Mr. Steven M. Zager

Mr. David L. Solomon

Mr. George A. Finley III

Mr. Steve L. Fox

The Honorable Joseph H. Zappala

Mrs. Lenise H. Stephenson

Dr. Jack M. Gill

Mr. Terry M. Giles

Dr. Joseph M. Grant

Mr. David M. Grimes II

Associate members

Mrs. Desiree Lyon Howe

Mr. Arden R. Grover

The Honorable Linda L. Addison

Mrs. Barbara Hurwitz

Mr. Ben A. Guill

Mr. Barry G. Andrews

Mr. George F. Kettle

Mrs. Gloria Hicks

Mr. Matthew Anthony

Mrs. Nancy G. Kinder

Mr. Yerger Hill III

Dr. W. Edwin Bosarge, Jr.

Dr. Henry A. Kissinger

Mr. Jeffrey C. Hines

Mr. I. Jon Brumley

Mr. David H. Koch

Mrs. Phyllis S. Hojel

Dr. Grace L. Butler

Mr. Mac Tichenor, Jr. Mr. Tony Vallone Mr. William M. Webster IV Mr. Herbert D. Weitzman Mrs. Sheridan Williams

Partners in Making Cancer History®

Partners in Making Cancer History® The University of Texas M. D. Anderson Cancer Center gratefully acknowledges the following individuals, foundations, corporations and others who made a commitment of at least $1,000 between Sept. 1, 2007, and Aug. 31, 2008.

3M Company A & R Foods, Inc. A G Equipment Company Mr. and Mrs. Robert L. Aaron Mr. and Mrs. Dennis Abbe Mr. and Mrs. Jerry Abbott Abbott Fund Employees of Abbott Laboratories The Jeanette Abbott Memorial Foundation Dr. and Mrs. Christian R. Abee Mr. Carlos A. Abello John and Virginia Abercrombie Mr. and Mrs. J. Michael Ables Mr. Peter Aboytes Abraxis BioScience, Inc. Mr. and Mrs. Larry J. Accardi Accudata Systems, Inc. Mr. and Mrs. Anthony L. Ach Mr. and Mrs. William R. Acquavella Ad Hoc Legal Ms. Ginger E. Adam Dr. Kenneth S. Adam and Ms. Gayle Goodman Adam & Company Barbara and Roy Adams Charles and Beverly Adams Mr. and Mrs. Craig S. Adams Elbert L. and Erin S. Adams Mr. Kevin Adams Mr. and Mrs. Money Adams Mr. and Mrs. Walter E. Adams Adams & Barclay Enterprises, Inc. Mr. and Mrs. Terence E. Adderley Addi’s Faith Foundation Mr. and Mrs. James S. Addison The Honorable Linda L. Addison and Mr. Max M. Addison Mr. and Mrs. Kevin L. Adds Dr. Miriam O. Adelson and Mr. Sheldon G. Adelson Dr. Miriam & Sheldon G. Adelson Medical Research Foundation Mr. and Mrs. Gerhard P. Adenacker

Adesa Dallas Mr. and Mrs. Jack Adkins ADS-Co., Inc. Advanced Beauty Systems, Inc. Advanced Health Media Advanced Radiation Physics Service, Inc. Advocare International, L.P. Advogent Group, Inc. Aflac Incorporated AGA Foundation for Digestive Health and Nutrition Agilent Technologies Mr. and Mrs. Avinash C. Ahuja AIC Ventures, L.P. Mr. and Mrs. Roger E. Ailes Mrs. Maria del Carmen Aja de Garcia Akin Gump Strauss Hauer & Feld LLP Mr. and Mrs. John E. Akitt Mr. Godswill Obot Akpabio Akron Community Foundation Alabama Nursing Home Association Mrs. William D. Albrecht Mr. and Mrs. George A. Alcorn Mr. and Mrs. Michael E. Aldredge Ms. Ruth A. Aldridge Mr. Miguel Aleman Mr. and Mrs. Charles D. Alexander Mr. and Mrs. James M. Alexander Mr. and Mrs. John D. Alexander, Jr. Joan and Stanford Alexander Alex’s Lemonade Stand Foundation Mr. Steven R. Alferi Mr. and Mrs. Rex E. Alford Albert and Margaret Alkek Foundation Mr. Jerry P. Allamon Allamon Tool Company, Inc. M. Diane and Joe M. Allbaugh Mr. and Mrs. Joe L. Allbritton The Allbritton Foundation Charles and Amy Allen Mr. Charles T. Allen Mr. Joseph Allen

Endowed distinguished university chairs* Harry Carothers Wiess Distinguished University Chair for Cancer Research

Robert C. Bast Jr., M.D. The Robert A. Welch Distinguished University Chair in Chemistry

Richard G. Brennan, Ph.D. Frederick F. Becker Distinguished University Chair for Cancer Research

Stanley R. Hamilton, M.D. Samsung Distinguished University Chair in Cancer Medicine

Waun Ki Hong, M.D. *As of February 2009

Mr. and Mrs. Lawrence Allen Mr. Michael H. Allen Mr. and Mrs. Robert H. Allen Rita Allen Foundation Allergan, Inc. Alliance of Cardiovascular Researchers Mr. Philip C. Allison Mr. and Mrs. Robert J. Allison, Jr. The Carolyn J. & Robert J. Allison, Jr. Family Foundation Allos Therapeutics, Inc. Johnnie R. Allred Aloka Mr. and Mrs. Juan F. Alonso Alpha Shirt Company AlphaMedica, Inc. Alpharma Pharmaceuticals LLC Mr. and Mrs. Robert C. Alspach Mr. and Mrs. Lawrence Altman Mr. Juan Alvarez Alveolus, Inc. Maurice Amado Foundation Dr. Paula Amaon and Mr. Gary P. Amaon Ambion, Inc. American Academy of Otolaryngology American Academy of Physician Assistants American Alloy Steel, Inc. and A. J. Moore American Association for Cancer Research American Association for Respiratory Care American Association of Physicists in Medicine American Brain Tumor Association American Cancer Society The American Endowment Foundation Employees of American Express The American Gastroenterological Association American Geriatrics Society American Heart Association-Texas The American Laryngological, Rhinological and Otological Society American Medical Association Foundation American Petroleum Institute American Shoreline, Inc. American Skin Association American Society for Therapeutic Radiology and Oncology American Society of Clinical Oncology American Society of Hematology American Steel & Aluminum Co., Inc. American Thyroid Association Amerita, Inc. Mr. John Young Ames Amgen, Inc. Mr. Ron Amini The Homer Ammann Trust Mr. Jack W. Amschwand Amschwand Sarcoma Cancer Foundation Anadarko Petroleum Corporation

Mr. and Mrs. Charles A. Anderson Mr. Charles B. Anderson Mr. and Mrs. Charles S. Anderson Mr. Douglas Anderson Ed and Sue Anderson Mr. and Mrs. Gregory Mark Anderson Mr. and Mrs. Jack R. Anderson Ms. Jill Elizabeth Anderson and Mr. Michael R. Smith John Henry and Dora Anderson The Honorable and Mrs. John S. Anderson Ken and Mary Anderson Mr. Kenneth W. Anderson Louis D. Anderson, DDS, MS Mr. and Mrs. Mark M. Anderson Mr. and Mrs. Richard P. Anderson Mr. Robert R. Anderson Mr. Robert W. Anderson Mr. and Mrs. Roy Anderson, Jr. Mr. and Mrs. Sydney J. Anderson Carl C. Anderson, Sr. and Marie Jo Anderson Charitable Foundation Robert F. & Marjorie Anderson Family Foundation M. D. Anderson Foundation Mrs. Adele W. Anding Mr. and Mrs. Barry G. Andrews Mr. and Mrs. Glynn Andrews The Honorable and Mrs. Michael A. Andrews Andrews Distributing of North Texas, Ltd. Glynn Andrews Family Foundation Andrews Kurth LLP Anglo-Suisse Offshore Partners, LLC Anheuser-Busch Foundation Eric and Cynthia Ankersen Anonymous Dr. Dina Anooshiravani Answer to Cancer Foundation Mr. and Mrs. Ronald E. Antes Mr. and Mrs. Laurence H. Anton AONE Institute for Nursing Leadership Research and Education Apache Corporation Applied Materials Aptia Systems The ARAMARK Charitable Fund at the Vanguard Charitable Endowment Program Mr. and Mrs. Rand Araskog Arc Specialties, Inc. Mr. and Mrs. Kirby Arceneaux Dr. and Mrs. Van M. Ardoin Arena Energy ARES Operations, LLC The Honorable and Mrs. George L. Argyros Argyros Family Foundation Dan and Mary Armour Mrs. Tobin Armstrong Estate of Verda A. Arney Mrs. Ann Arnold Becky and Truman Arnold Mr. and Mrs. Ken Arnold Laura and John Arnold Mrs. Louise T. Arnold The Arnold Foundation

Mr. and Mrs. John S. Arnoldy Mr. William G. Arnot, Jr. Mr. and Mrs. J. Timothy Arnoult Mr. and Mrs. Mark I. Arnove Arrigo Dodge Chrysler Jeep Mr. Zane W. Arrott Ms. Yvonne Arthur Mr. and Mrs. Vijay K. Arya Mr. H. G. Ash Mr. John K. Ashby Mr. and Mrs. Richard W. Ashcroft Mr. and Mrs. Jeffrey E. Asmus Dr. Rosalyn Assef and Mr. James Assef Association of Physician Assistants in Oncology Astellas Pharma US, Inc. Astra Tech AB AstraZeneca LP Astros in Action Foundation A-T Children’s Project AT&T Foundation AT&T Inc. Mr. and Mrs. Ural Ataman Atlanta United Fund Mr. and Mrs. Morris Atlas Mr. and Mrs. J. Evans Attwell Nancy and Kirby Attwell Atwood Oceanics Management, LP Dr. and Mrs. Arthur I. Auer Austin Community Foundation Austin Vintage Guitars Auto Insurance Discounters, Inc. Avaya Mr. and Mrs. James Avery Mrs. Lorece M. Avery Mr. Andrew Avillo and Mrs. Maria Arwitz Avon Foundation Mr. and Mrs. Robert R. Awe Axcan Scandipharm Inc. The Ayco Charitable Foundation Mr. and Mrs. R. C. Ayers, Jr. Mr. and Mrs. Edward Azar Mr. and Mrs. Richard Azar Mr. and Mrs. Moshe Azoulay David and Linda Bachrach Mr. and Mrs. Ramon F. Baez Mr. James E. Bagwell Mr. Dean H. Bailey Edward Bailey and Nancy K. Landfish, M.D. Mr. Kyle L. Bailey Mr. Thomas B. Baird Mr. and Mrs. Weldon R. Baird Mr. and Mrs. Richard O. Baish Ms. Carole H. Baker and Mr. William H. Tyler Mr. and Mrs. Darrel P. Baker Ms. Dusty Baker Mrs. Elizabeth H. Baker The Honorable and Mrs. James A. Baker III Mr. James A. Baker IV Mr. James B. Baker Jerry and Rebecca Baker Mr. Lewis T. Baker, Jr. Dexter F. and Dorothy H. Baker Foundation

M. D. Anderson Annual Report 2007-2008 Baker Hughes Foundation Mr. and Mrs. George A. Baldwin, Jr. Mr. and Mrs. Robert C. Balfour III Mr. John G. Ball Mr. and Mrs. Claude M. Ballard Baltimore Community Foundation Mr. Ambrose J. Baltz, Jr. Mr. and Mrs. Robert S. Bambace Mr. and Mrs. P. V. Banavalkar Bank of America Foundation Mr. and Mrs. Charles H. Bankhead Mr. David R. Banks Mr. Billie B. Barclay, Jr. Mr. and Mrs. Ron W. Barclay Bard Access Systems, Inc. Mr. and Mrs. Paul A. Barenkamp Mr. and Mrs. Edward E. Barham Mr. and Mrs. Lin Barker Mr. C. L. Barlow Mr. Bob R. Barnard The Honorable and Mrs. Ben F. Barnes Mrs. Geraldine V. Barnes Mr. and Mrs. Leroy R. Barnes, Jr. Mr. and Mrs. Steven E. Barnes Mr. Arnold R. Barnett Mr. and Mrs. Eliot B. Barnett Mr. Robert N. Barnett Mr. and Mrs. Charles Barney Barney Corporation Ms. Vicki A. Baroco J. H. Baroco Foundation, Inc. Dr. and Mrs. F. T. Barr Mr. and Mrs. James N. Barrett Michael and Cindy Barrett Barriere Construction Co., L.L.C. General Robert H. Barrow Mr. and Mrs. James A. Bartlett Mr. and Mrs. James R. Bartley Mr. and Mrs. Michael G. Bartolotta Mrs. Iva Lea Barton Mr. and Mrs. Sid R. Bass Ms. Kim M. Bates Mr. and Mrs. Thomas R. Bates, Jr. Mr. Lawrence E. Bathgate II Ms. Nancy A. Batt Battelle & Battelle LLP Battelle Financial Services, LLC Mr. and Mrs. James A. Baudin Mr. and Mrs. Brant R. Bauer In Memory of Susan Baughman Mr. Kelly H. Baxter The Baxter International Foundation Bayer HealthCare Pharmaceuticals Estate of Margaret L. Bayhi Baylor College of Medicine BCM & Associates, Inc. Mr. and Mrs. Carty Beal Nancy and Barry Beal Mr. and Mrs. Spencer Beal Ms. Cathryn Beamon James R. and Traci Beamon Bear Lakes Country Club, Inc. Mr. and Ms. Brett Beardsley The Theodore and Beulah Beasley Foundation, Inc. Mr. Wayne Beason Mr. and Mrs. Robert E. Beauchamp Toni and Jeffery Beauchamp Mr. and Mrs. Joe Beaud, Jr. Beaumont Iron and Metal Corporation Bechtel Group Foundation Mr. and Mrs. Robert Beck Beck Bros., Inc. Mr. and Mrs. Allen J. Becker Mr. and Mrs. R. William Becker Mr. Thomas Becker Becker Family Foundation Beckman Coulter Foundation Mr. and Mrs. Harry G. Beckner Mr. and Mrs. William W. Bedford

M. D. Anderson President John Mendelsohn, M.D., helps recognize CBS News’ chief Washington correspondent and moderator of “Face the Nation,” news veteran Bob Schieffer (left), with the inaugural Making Cancer History® Award. The award honors him for embodying M. D. Anderson’s core values of caring, integrity and discovery. Schieffer interviewed actor Tom Hanks during A Conversation With a Living Legend, Nov. 15, 2007, in Washington, D.C. The event raised more than $600,000. Bedford Central School District Mr. and Mrs. Louis A. Beecherl, Jr. Mr. David C. Beeman Beeman Strong & Co., Inc. Mr. and Mrs. Gary W. Beene Dr. Kenneth R. Beer JoAnna and Robert Behl Mr. and Mrs. Brent R. Behrman Mr. and Mrs. Alan T. Beimfohr Martin and Kathleen Beirne Mr. James P. Bell, Jr. Mrs. Patsy A. Bell Mr. Ray L. Bellande Mr. and Mrs. James Bellinger Ms. Yvonne M. Bellinger Robert E. Belville Jr. Beloco Foundation, Inc. Bencor Corporation of America Mrs. Sophia Bender Mr. and Mrs. Randall Benderson Mr. Mike S. Benestante Dr. and Mrs. Robert S. Benjamin Mr. Ned W. Bennett and Ms. Sandra G. Zane Zane Bennett Family Foundation Mr. Marc Bension Mrs. Lloyd M. Bentsen, Jr. Bentwater Ladies Organization Mr. and Mrs. Michael M. Berger Mr. and Mrs. Steve Bergstrom Bergstrom Family Foundation Howard and Wendy Berk Ms. Evelyn Berkowitz/In memory of Celia Berkowitz Mr. and Mrs. Edward Berrio Mr. and Mrs. Frank R. Berry Mr. Fred Berry Sally and Buford Berry Mrs. Eugenia Bertetti The Eugenia and Lawrence A. Bertetti Foundation Mr. Robert P. Bertrand Mr. and Mrs. Gilbert J. Besing The Beta Foundation Mr. and Mrs. Gordon Bethune Bethyl Laboratories, Inc. Mr. David C. Betz Mr. and Mrs. Robert H. Beuttas The Beverage Institute for Health & Wellness

Mr. Jeffrey J. Beyda David J. Beyda Memorial Foundation Mr. and Mrs. Robert D. Beyer Ms. Janet G. Beynon Mr. Richard H. Bickerstaff Mr. Robert D. Bickford, Jr. Mr. William M. Biddison Margaret T. Biddle Foundation Mrs. Diane Bigelow Mrs. Carole Biggio Robert Bilger Mr. and Mrs. Thomas J. Billings Billy’s Pit Bar-B-Q Mr. and Mrs. Thomas W. Binning Biocare Medical, LLC Biogen Idec Biomedical Research Foundation Biomet, Inc. bioTheranostics, Inc. BIP Crude Stephen and Mary Birch Foundation Mr. and Mrs. John A. Bird The Bireley Family Foundation and Frank and Betty Bireley Mr. and Mrs. William M. Birk Bobby Birkelbach Benefit Mr. and Mrs. David J. Bishop Ms. Susan E. Bishop and Mr. Howard L. Abramson Bishop Lifting Products, Inc. Mr. and Mrs. Howard C. Bissell Mr. Robert O. F. Bixby BJ’s Restaurant & Brewery BJ’s Restaurants Foundation Inc. Mr. and Mrs. John D. Black Dr. Karen S. Black Mr. R. David Black Mr. and Mrs. Robert M. Black III Black Gold Rental Tools, Inc. Mr. and Mrs. Gary W. Blackie Blackwell & Associates Mr. and Mrs. Donald G. Blair Mrs. Mary Criner Blake Mr. and Mrs. William D. Blake Mr. and Mrs. Hayne Blakely Mr. and Mrs. Brett J. Blakey The Honorable and Mrs. James J. Blanchard Mr. Richard Bland Mr. and Mrs. Jack S. Blanton, Sr.

Mr. and Mrs. Steven R. Block Mr. John W. Blome Mr. and Mrs. Robert A. Blome Mr. and Mrs. Mike Bloom Blue Bell Creameries, L.P. Blue Water Express Bluebonnet Electric Cooperative, Inc. BMC Software Edwin L. and Carla M. Boardman Mr. and Mrs. David M. Boatner Boatner Family Foundation Bob Grimmer Electric, Inc. Mr. and Mrs. James R. Bobo Dr. and Mrs. James R. Bocell, Jr. Mr. Philip L. Boehk Mr. Clyde L. Bohannon, Jr. Ms. Gretchen K. Bohnert Mr. and Mrs. William R. Boles, Sr. Mrs. Betsy C. Bolin Mr. Roscoe A. Bolton Mrs. Ina Bond Mr. and Mrs. Jeff W. Bonham Mrs. Jeanie P. Bonner Mr. Kerry G. Bonner Ms. Townley Everette Bonney Mr. and Mrs. James A. Boone Ms. Mary B. Booth Mr. and Mrs. Giorgio Borlenghi Mr. and Mrs. Gordon P. Borrell Mr. and Mrs. James L. Bosler Mr. and Mrs. Dwight Bostic Boston Biochem, Inc. Boston Medical Products, Inc. Boston Scientific Corporation Mrs. Beth Ann Botros Mr. and Mrs. Winston F. Bott, Jr. Mr. and Mrs. Brett Bottcher Ms. Jean E. Boudreaux Mr. and Mrs. E. H. Boullioun, Jr. Mr. and Mrs. Douglas J. Bourne Mrs. Ruth McLean Bowers Ruth McLean Bowman Bowers Foundation S. Theresa Bowers Revocable Trust Mrs. Diane E. Bowes Mr. and Mrs. John D. Boxx Robert and Julia Boyce Mr. Doug Boyd James M. and Lorelee A. Boyd

Mrs. Patricia K. Boyd Mr. and Mrs. Stephen L. Boyd Dr. William A. Boyd Dr. and Mrs. L. Eamonn Boyle Mr. Nicholas H. Boyle Boyle International LLC BP BP Foundation, Inc. Mr. and Mrs. Bryan E. Bracewell Ms. Billye B. Bradley Mr. and Mrs. Francis R. Bradley Mr. and Mrs. Jeff Bradley Mr. and Mrs. Paul R. Bradshaw Mr. and Mrs. Sam K. Bradshaw The Brain Tumor Society Ms. Jane E. Brammer Mr. David Branco Brandes Brothers Constructors, Inc. Mr. Paul R. Brandt Mr. Glenn S. Brant Bratton Family Foundation Mr. Samuel K. Bravenec and Mrs. Tricia Benestante Bravenec Major General Leslie W. Bray, Jr. Ret. Breast Cancer Relief Foundation Breast Cancer Research Foundation Mr. James L. Breaux Mr. Erich E. Bredl Mr. and Mrs. Daniel L. Breeding Mrs. Patricia Breen Dr. Richard G. Brennan Mrs. Anne R. Brennan- Hooser Bric Brac’n Brass at the Quarry Bridgeway Capital Management, Inc. Bridwell Oil Company Ms. Leslie K. Brier Mr. Richard W. Brietzke Mrs. Faye C. Briggs Mr. and Mrs. Louis R. Brill Mr. and Mrs. Charles C. Brinkley Dr. and Mrs. William R. Brinkley The Honorable Dolph Briscoe, Jr. Ms. Jan Wallace Briscoe Ms. Mary E. Briscoe Mr. and Mrs. David A. Bristol, Jr. Bristol-Myers Squibb Company Bristol-Myers Squibb Foundation, Inc. Mr. and Mrs. B. Daryl Bristow Britten Fund 73

Partners in Making Cancer History® Endowed distinguished chairs* Gilbert H. Fletcher Memorial Distinguished Chair

Kie-Kian Ang, M.D., Ph.D.

Jane and John Justin Distinguished Chair in Leukemia Research in Honor of Dr. Elihu Estey

Larry W. Kwak, M.D., Ph.D.

Robert D. Moreton Distinguished Chair in Diagnostic Radiology given by W. A. “Tex” and Deborah Moncrief, Jr.

Chusilp Charnsangavej, M.D.

Charles A. LeMaistre Distinguished Chair in Thoracic Oncology given by W. A. “Tex” and Deborah Moncrief, Jr.

Alando J. Ballantyne Distinguished Chair of Head and Neck Surgery

Vivian L. Smith Distinguished Chair in Immunology

Scott M. Lippman, M.D.

Gary L. Clayman, M.D., D.D.S., D.M.D.

Yong-Jun Liu, M.D., Ph.D.

Hubert L. and Olive Stringer Distinguished Chair in Oncology in Honor of Sue Gribble Stringer

Roy M. and Phyllis Gough Huffington Clinical Research Distinguished Chair in Urologic Oncology

James D. Cox, M.D.

Christopher J. Logothetis, M.D.

Nathan W. Lassiter Distinguished Chair in Urology

Lockton Distinguished Chair in Pancreatic Cancer Research

Bogdan A. Czerniak, M.D., Ph.D.

Craig Logsdon, Ph.D.

R. E. “Bob” Smith Distinguished Chair in Cell Biology

John S. Dunn, Sr. Distinguished Chair in Diagnostic Imaging

Isaiah J. Fidler, D.V.M., Ph.D.

William A. Murphy, Jr., M.D.

Boone Pickens Distinguished Chair for Early Cancer Prevention

Barnts Family Distinguished Chair for Cancer Research

William K. Plunkett, Jr., Ph.D.

Michele Follen, M.D., Ph.D.

Senator A.M. Aikin, Jr. Distinguished Chair

J. Taylor Wharton, M.D., Distinguished Chair in Gynecologic Oncology

Raphael E. Pollock, M.D., Ph.D.

David M. Gershenson, M.D.

Bud Johnson Clinical Distinguished Chair

Olla S. Stribling Distinguished Chair for Cancer Research

Jack A. Roth, M.D.

Ellen R. Gritz, Ph.D.

Anne C. Brooks and Anthony D. Bullock III Distinguished Chair in Neurosurgery

W. A. “Tex” and Deborah Moncrief, Jr. Distinguished Chair in Urology

Raymond E. Sawaya, M.D.

H. Barton Grossman, M.D.

Gerald Dewey Dodd, Jr. Distinguished Chair in Diagnostic Imaging

Ruth Legett Jones Distinguished Chair

Paul M. Silverman, M.D.

Mien-Chie Hung, Ph.D. Robert A. Welch Distinguished Chair in Chemistry

*As of February 2009

William H. Klein, Ph.D. Broad Oak Energy, Inc. Ms. Sherry M. Broadhead Mr. and Mrs. Joel Brochstein Raymond and Susan Brochstein Mr. J. Vaughn Brock Dr. Lynne Brock/Brock Endodontics Mr. and Mrs. Todd O. Brock Todd Brock Family Foundation Brock Family Fund The Broesche Family Foundation The Broitman Foundation, Inc. Mr. Ben A. Brollier Mr. and Mrs. Henry T. Brooks Mr. and Mrs. Thomas J. Brorby Mrs. Charles Broudy Mr. Joseph E. Broussard II Broussard Group Brower Insurance Agency, LLC Mrs. Ann G. Brown The Honorable Ann Brown and Mr. Don Brown Elena and Bob Brown Mr. and Mrs. F. E. Brown, Jr. Mr. and Mrs. James D. Brown Mr. and Mrs. Joseph C. Brown Mrs. Marjorie E. Brown Estate of Sylvia H. Brown Mr. and Mrs. Thomas D. Brown Mr. Willard B. Brown Mr. and Mrs. William C. Brown T. J. Brown & C. A. Lupton Foundation, Inc. W. L. Lyons Brown Foundation 74

The Brown Foundation, Inc. Brown Water Marine Service, Inc. Miss Ashley Browning Brownstein Hyatt Farber Schreck, P.C. Mrs. Nancy T. Broyles Mr. and Mrs. Lou Brucculeri Mrs. Jerry Bruce Mr. and Mrs. Paul L. Bruce and Family The Samuel B. and Lorena J. Bruce Charitable Trust Dr. and Mrs. George A. Brugnoli Mr. and Mrs. D. Forrest Brumbaugh The Brunetti Foundation Mr. and Mrs. William G. Brunger Donald R. Brunstrum Foundation Ms. Roxanne Brust Mrs. Carole Lou Bruton Mr. Ralph C. Bruton Bryan Corporation Mrs. Beverly Buckley Ms. Carol M. Buckley Mr. James Buckley Mr. and Mrs. Jack L. Buckner Mr. and Mrs. W. P. Buckthal Mr. and Mrs. Charles M. Buenger Mr. and Mrs. William T. Buida Mr. and Mrs. Jim P. Buller Mr. and Mrs. R. Gantt Bumstead Mr. and Mrs. David J. Bunce Mr. Martin Bunge Mr. Harold R. Burch Dan and Penny Burck

Mr. and Mrs. Scott Burford Mr. and Mrs. Thomas V. Burford Philip Burguieres Mr. and Mrs. Earl P. Burke, Jr. Mr. and Mrs. Kenneth M. Burke Mr. and Mrs. William C. Burkett Burlington Northern Santa Fe Foundation Mr. Charles R. Burnett III Mr. and Mrs. R. Hayden Burns Mr. and Mrs. Robert L. Burns, Jr. Mrs. Susan E. Burns Toni and Mark Burns Burroughs Wellcome Fund Miss Betsy Burrows Mr. Jeff Burrows Burrus Real Estate Co. Mr. and Mrs. David M. Burwen Mr. and Mrs. Robert A. Buschman Mrs. Cheri L. Bush Mr. F. L. Bush The Honorable and Mrs. Frederick M. Bush Grace L. Butler, Ph.D. Mrs. Jane M. Butler Mr. and Mrs. John B. Butler Ms. Kelly Butler Mr. and Mrs. Richard E. Butler Mr. and Mrs. Thomas W. Butler Charles Butt Mr. and Mrs. Herbert H. Butt Mr. and Mrs. Lloyd P. Byler

Mr. and Mrs. Jason C. Byrd Mr. Steve Byrne and Ms. Kerry A. Shannon Mr. and Mrs. John J. Byrnes C C Bay LLP C R Cattle Company Burt and Hermys Cabanas Cabot Oil and Gas Corporation Cactus Builders, Inc. Mr. Joseph R. Cade Estate of Kathleen C. Cailloux Kathleen C. Cailloux Family Foundation Mrs. Mary H. Cain The Effie and Wofford Cain Foundation Gordon and Mary Cain Foundation Calco Contracting, Ltd. Mr. James A. Caldera Mr. and Mrs. Charles Caldwell Mr. and Mrs. John J. Caldwell California Medical Devices, Inc. Mr. and Mrs. Verlin Callahan Mrs. Woody Callan Mr. and Mrs. Dean Lynn Callender Mr. and Mrs. Edward L. Callender Mrs. Verline Calley Mr. Craig J. Calligan Mr. Paul C. Calvino Cambridge Endoscopic Devices, Inc. Mr. Cleveland E. Campbell Ms. Eileen M. Campbell and Mr. Douglas D. Perley

Mr. and Mrs. John H. Campbell Mr. and Mrs. Lynn D. Campbell Mr. and Mrs. Robert S. Campbell Mrs. Clara G. Campbell Cancer Fighters of Houston, Inc. Cancer Foundation for Melanoma Research, Inc. Cancer Prevention and Research Institute of Texas Cancersucks.com Mr. and Mrs. Rod Canion Mr. and Mrs. Joseph C. Canizaro Mr. and Mrs. Gardner W. Cannon Mr. and Mrs. L. Kinder Cannon III Mr. Rudolph D. Cannon Mr. and Mrs. James J. Cano Ms. Jo Canter Dr. and Mrs. Joel Canter Mr. James W. Cantor Mrs. Gloria L. Cantu Carlos H. Cantu Family Foundation Canyon Creek Country Club Mr. Paul E. Canzian Capital Bank Mr. Charles W. Cappel Capstar Commercial Real Estate Services Ltd. Mr. and Mrs. Renato E. Cardenas Cardinal Health Cardinal Health Medical Products and Services Mr. Charles Carducci Mr. and Mrs. Bradley Cardwell Mr. John R. Cargile Mr. and Mrs. Terry L. Carius Mrs. Emory T. Carl Mr. and Mrs. Kris M. Carlson Dr. and Mrs. Milton R. Carlson Ms. Sheryl Carlson Carmel Pharma, Inc. Estate of Nancy D. Carmichael Mr. and Mrs. Brian J. Carmines David M. Carmines Memorial Foundation, Inc. Mr. David S. Carnahan Mr. and Mrs. Mark S. Carnes Mr. and Mrs. Michael M. Carnes Dr. and Mrs. Richard L. Carnovale Mr. and Mrs. William A. Carpenter, Jr. Carpenter Contractors of America, Inc. The Carrig Family Carrizo Oil & Gas, Inc. Mr. Daniel J. Carroll Mr. and Mrs. Philip J. Carroll Mr. and Mrs. Jeff Carter Mr. Jeffrey A. Carter Mr. and Mrs. Paul R. Carter Mr. W. Michael Carter Jeffrey A. Carter Foundation The Scott Carter Foundation Mr. and Mrs. Gary J. Cartright Estate of Cherie Glynn Franks Carver Mrs. Sally A. Carwile Mr. Ronald A. Case Wendy Will Case Cancer Fund, Inc. Mr. and Mrs. Bob Casey III Mr. and Mrs. John W. Casey Mr. and Mrs. Frank J. Cassata Castex Energy, Inc. Mr. and Mrs. Robert B. Caswell Caterpillar Foundation Linda and Conley Cathey Mr. and Mrs. Earl D. Catlett The Honorable and Mrs. Henry E. Catto, Jr. Catto Charitable Foundation Gloria East Cave Mr. and Mrs. Jack E. Caveney Mr. and Mrs. Robert L. Cavnar Mr. and Mrs. Clarence P. Cazalot, Jr. CBCE Celgene Corporation

M. D. Anderson Annual Report 2007-2008 Cell Centric Estate of Joe Celli CenterPoint Energy Central Management, Inc./Victor E. Vacek, Jr. Central Plumbing and Electric Supply Co. Cephalon, Inc. Mr. John L. Cerny Mr. Gonzalo J. Ceron Mrs. Mary E. Certain CFP Foundation Mr. and Mrs. D. B. H. Chaffe III Mr. and Mrs. Eugene C. Chambers The Carole and Gene Chambers Foundation Chameleon Communications Intl. Mrs. Randa Chammas Ms. Christine B. Champion Mr. and Mrs. Joseph Chance Mr. and Mrs. E. Thomas Chaney Mr. Peter J. Chaney The Chaney Family Foundation Dr. and Mrs. Jack H. Chang Mr. and Mrs. Oliver K. Chang Mr. and Mrs. James Chao The Chaplaincy Fund, Inc. Mr. and Mrs. Alexander J. Chapman Estate of J. C. Chapman The Honorable Jim Chapman Mr. and Mrs. John O. Chapman Mrs. Roy T. Chapman The Mary K. Chapman Foundation Chapman Foundations Management, LLC Mr. and Mrs. O. Don Chapoton Mrs. Carol S. Charles Charles N. White Construction Company Charles River Laboratories, Inc. Mrs. Laurie Charsinsky Mrs. Catherine D. Chase Ms. Tipaporn Chearavanont Dr. Joseph J. Chen Mr. and Mrs. William Cheney Cheniere Energy, Inc. Mr. and Mrs. James Michael Chennault Mr. and Mrs. C. Dan Chenoweth Chesapeake Energy Corporation Mr. and Mrs. Stephen D. Chesebro’ Mr. James A. Chesebrough, Jr. Mr. and Mrs. Robert W. Chesner, Jr. Employees of Chevron Chevron Humankind Chevron Phillips Chemical Co. LP Dr. and Mrs. Joseph S. Chiang Mr. and Mrs. Paul J. Chiapparone Chicago Mercantile Exchange Foundation Childhood Brain Tumor Foundation Estate of Leonard H. Childress Mr. and Mrs. William C. Childs William C. & Antoinette M. Childs Foundation Chili Appreciation Society International, Inc.-Houston Pod Al and Lenore Chilton Foundation Ms. Carol L. Chimera Mr. and Mrs. Alexander E. Chionsini Mrs. Carolyn Chipman Mr. Jack R. Chittim Mr. and Mrs. Sherman S. Chiu Chivaroli and Associates, Inc. Choose Hope, Inc. Mr. David M. Chorneyko Ms. Shirley Chow David A. and Mary Jo Christensen Mr. and Mrs. Gary R. Christopher Mr. and Mrs. Russell P. Chubb Ms. Gayle S. Churchill Cinemark USA, Inc. The Cipione Family Foundation Cisco Energy, LLC

General and Mrs. Marc A. Cisneros CITGO Petroleum Corporation Citi Global Impact Funding Trust, Inc. City of Houston, Texas Mr. and Mrs. Robert Cizik Robert and Jane Cizik Foundation Mr. Charlie Claffey Claffey Pools Dr. and Mrs. Thomas O. Clanton Bryan and Susan Clark Mr. Collen A. Clark Mr. and Mrs. Craig Clark Mr. Jeffrey F. Clark Meredith and Tom Clark Ms. Priscilla M. Clark and Mr. Robert J. Ensworth Jr. Mr. and Mrs. Richard R. Clark Ms. Robbin Clark Mr. Robert H. Clark Mr. and Mrs. John U. Clarke Mr. William E. Clarke and Ms. Michelle Witcher Mr. and Mrs. Charles F. Clarkson III Mr. and Mrs. David A. Clay Cleveland Clinic The Cleveland Foundation Mr. Loyd H. Clevenger Mr. and Mrs. James F. Clingman, Jr. Mr. Jerry G. Clinton Clinton Koerth and Finley Resources, Inc. CLL Global Research Foundation Mr. and Mrs. Perry W. Cloud, Jr. CMC Rebar CNA Foundation Coastal Spray Company Coastal Supply Co., Inc. Cobalt International Energy, L.P. The Coca-Cola Foundation Mr. and Mrs. Allen H. Cocanougher Cocanougher Foundation Mr. and Mrs. Alan R. Cochran Mr. Donald Cochran Mr. and Mrs. Ernest H. Cockrell Cockrell Family Fund The Cockrell Foundation Cockrell Interests, Inc. Mr. David B. Coe Mr. and Mrs. Arthur B. Coen, Jr. Mr. and Mrs. Roy C. Coffee, Jr. Mary and Edward Coffey Cogenix, LLC Barton and Phyllis Cohen Mr. and Mrs. James H. Cohen Michael T. Cohen, Dr. Arielle Hart, Jerome M. Cohen, and Robin Reinach Lynne Cohen Foundation for Ovarian Cancer Research Mr. and Mrs. Morton A. Cohn Mr. and Mrs. Joseph F. Colaruotolo Mr. and Mrs. Don J. Colchin Mr. and Mrs. Carl W. Cole Mr. and Mrs. Edward Cole Mr. Jeffrey S. Cole Dr. and Mrs. Joseph W. Cole Mr. Kermit D. Cole Estate of Marguerite Cole Mr. Robert Cole Sue and Jim Cole The Ashley Fister Cole Foundation Cole Foundation Mr. and Mrs. James E. Coleman, Jr. Mr. and Mrs. Lynn R. Coleman Mr. and Mrs. Ronald M. Coleman Mr. Stephen M. Coleman Mr. and Mrs. Stuart Coleman Mr. and Mrs. Terry N. Coleman Mr. and Mrs. William T. Coleman Arlette & William J. Coleman Family Foundation Inc. Colemont Brokerage Group, Inc. Mr. and Mrs. Edward T. Colligan

Endowed chairs* M. G. and Lillie A. Johnson Chair for Cancer Treatment and Research

James L. Abbruzzese, M.D. Paul and Mary Haas Chair in Genetics in Honor of Amanda Marie Whittle

Michael Andreeff, M.D., Ph.D. Hubert L. Stringer Chair in Cancer Research

Ralph B. Arlinghaus, Ph.D. Ben F. Love Chair in Cancer Research

Richard R. Behringer, Ph.D.

Moshe Talpaz Endowed Chair in Immunology

Patrick Hwu, M.D. Kelcie Margaret Kana Research Chair

Hagop M. Kantarjian, M.D. Dr. Kenneth B. McCredie Chair in Clinical Leukemia Research

Michael J. Keating, M.B. Mosbacher Pediatrics Chair

Eugenie S. Kleinerman, M.D. Anderson Clinical Faculty Chair for Cancer Treatment and Research

Frank T. McGraw Memorial Chair in Cancer Research

Razelle Kurzrock, M.D.

Donald A. Berry, Ph.D. Frank T. McGraw Memorial Chair in the Treatment of Cancer

Eduardo Bruera, M.D. Ferenc and Phyllis Gyorkey Chair for Research and Education in Pathology

Janet M. Bruner, M.D. Frank T. McGraw Memorial Chair in the Study of Cancer

Thomas A. Buchholz, M.D.

Bernard W. Biedenharn Chair in Cancer Research

Victor A. Levin, M.D. Irving and Nadine Mansfield and Robert David Levitt Cancer Research Chair

Reuben Lotan, Ph.D. Mattie Allen Fair Research Chair

Guillermina Lozano, Ph.D. Ann Rife Cox Chair in Gynecology

Robert C. Hickey Chair in Clinical Care

Richard E. Champlin, M.D. Charles B. Barker Chair in Surgery

Steven A. Curley, M.D. Mary Beth Pawelek Chair in Neurosurgery in Honor of Dr. and Mrs. Samuel Dickens Bugg and Mr. and Mrs. Albert F. Pawelek

Franco DeMonte, M.D.

Gordon B. Mills, M.D., Ph.D. Larry and Pat McNeil Chair in Radiation Oncology Honoring Dr. James D. Cox

Radhe Mohan, Ph.D. David Bruton, Jr. Chair

Garth Powis, D.Phil. Sue and Radcliffe Killam Chair

Louise C. Strong, M.D.

Rebecca Meyer Brown and Joseph Mellinger Brown Chair in Basic Science Research

Sharon R. Dent, Ph.D.

The Cullen Trust for Health Care Chair in the Department of Health Disparities Research

David W. Wetter, Ph.D.

J. Ralph Meadows Chair in Carcinogenesis Research at Science Park–research Division

John DiGiovanni, Ph.D.

Betty B. Marcus Chair in Cancer Prevention

Xifeng Wu, M.D., Ph.D.

Lee M. Ellis, M.D.

Margaret and Ben Love Chair in Clinical Cancer Care in Honor of Dr. Charles A. LeMaistre

Ruth Harriet Ainsworth Research Chair in Developmental Therapeutics

*As of February 2009

William C. Liedtke, Jr. Chair in Cancer Research

Emil J Freireich, M.D.

W.K. Alfred Yung, M.D.

Nellie B. Connally Chair in Breast Cancer

Gabriel N. Hortobagyi, M.D. Mr. and Mrs. Rick Collins Ron and Barbara Collins Mrs. Virginia Collins Columbia Artists Management LLC Dr. and Mrs. Charles J. Colvin Comac Fixtures, Inc. Combined Federal Campaign of the Texas Gulf Coast Mr. Jay Comeaux Comiskey Foundation Commonwealth Foundation for Cancer Research Communities Foundation of Oklahoma Communities Foundation of Texas

The Community Foundation for Greater Atlanta, Inc. Community Foundation for Southeast Michigan Community Foundation of Greater Memphis Community Foundation of Jackson Hole The Community Foundation of Louisville, Inc. The Concordia Lutheran High School Mr. and Mrs. Michael M. Cone Conley Lott Nichols of Texas, Inc. CONMED Corporation Estate of Kathleen Conn Mr. and Mrs. John B. Connally III

Mr. and Mrs. Mark M. Connally Mr. Michael K. Connally Mr. Bruce A. Connell Mrs. Charlyne Connelly Mrs. Dorothy A. Connelly Mr. Jason R. Connelly Mr. Jeffrey Connelly Mr. and Mrs. Marvin G. Conner Mr. William Conner Conner Industries, Inc. Mr. and Mrs. Robert C. Connor ConocoPhillips Inc. Mr. Joseph John Conradi Mr. and Mrs. Oliver A. Conrads Dr. and Mrs. Francis P. Conroy 75

Partners in Making Cancer History®

Gabriel Hortobagyi, M.D., chair of M. D. Anderson’s Department of Breast Medical Oncology, addresses a gathering at the unveiling of two American Airlines planes bearing the Susan G. Komen for the Cure® trademark pink ribbons. The airline announced it would fund Komen’s first Promise Grant — $7.5 million to study and treat inflammatory breast cancer at M. D. Anderson’s Morgan Welch Inflammatory Breast Cancer Research Program and Clinic. Consolidated Treatment Systems, Inc. Mr. and Mrs. Anthony Constant Mr. Thomas V. Constantino Mr. Marcus P. Contreras Mr. James R. Contway Estate of Allie Crockett Conway, Jr. Mr. Michael D. Conway Phil and Suzie Conway Mr. Joseph A. Conza Mr. and Mrs. Brian C. Cook Mr. Robert L. Cook Mr. and Mrs. Dave Coolidge Mr. and Mrs. Glenn D. Cooper Mr. and Mrs. J. Robert Cooper Estate of R. W. Cooper Cooper Industries Foundation Coors Distributing Company of Fort Worth Copano Energy, LLC Mrs. Patricia A. Corbett Ms. Maureen A. Corcoran Cordillera Energy Partners II, LLC Estate of Edna May Corey Dr. Yvonne C. Cormier and Mr. Rufus Cormier, Jr. Mr. and Mrs. Lovick P. Corn Cornerstand Brands, Inc. Corporate Retreats International Mr. and Mrs. James F. Corporron Mr. Jose Correa, Jr. Mr. and Mrs. Charles A. Correll Dr. and Mrs. James A. Corwin Cory’s Unlimited, Inc. Shirley and J. B. Coskey Mr. and Mrs. Olen Cothron Cothron Partnership No. 2 Cheryl and David Cotner Mr. and Mrs. Jeff Cotner Ms. Mariana P. Cotten Mr. and Mrs. David Cottrell Mr. and Mrs. Warren C. Coughlin Ms. Sylvia Y. Coulter Mr. Leslie K. Courson Mr. John P. Courtney 76

Ms. Janet W. Cousins Covidien Ltd. Mr. and Mrs. James T. Covin Mr. and Mrs. Philip Cowan Mr. Robert J. Cowan Mr. Edward J. Cowell, Jr. Mr. and Mrs. Michael C. Cowen Mrs. Sam E. Cowin Mr. Robert E. Cowley, Jr. Mr. and Mrs. Edward A. Cox, Jr. Ms. Winifred Cox David and Lois Coyle Mr. and Mrs. Alan M. Craft Mr. and Mrs. Earle M. Craig, Jr. Mrs. Ann Crain The Crain Foundation Crain-Maling Foundation Robert S. Craine and Kathleen B. Craine Mr. Claude L. Crane Thomas and Christine Cravens Crawford Renovation Group Mr. and Mrs. Nance G. Creager Creative Dimensions Credit Suisse Securities (USA) LLC Mr. and Mrs. John W. Creecy Creighton University School of Medicine Mr. and Mrs. Richard L. Crider Crimson Exploration Inc. Crockett County Mining Venture No. 1, Ltd. Mr. and Mrs. Chris Crosby Mr. and Mrs. Christopher J. Crosby, Sr. Mr. Howard M. Crosby Ms. Jane Crosby Ms. Amanda B. Cross RNR Cross Family Foundation Mr. Steven Crot Mr. and Mrs. Trammell Crow Crownquest Operating, LLC Mr. Lee J. Crowther Robert P. Crozer Family CRR Ventures, LLC

Mr. and Mrs. Thomas H. Cruikshank, Sr. Mr. and Mrs. Gary T. Crum Mr. and Mrs. E. Lea Crump Mr. and Mrs. Richard K. Crump The Crump Foundation Mr. and Mrs. Edward E. Crutchfield Crutchfield Family Foundation Mr. Darwin Cruz Cruzin to Cure Mr. and Mrs. Les T. Csorba Cubist Pharmaceuticals, Inc. Mr. and Mrs. Don Culbert Culinary Travel Adventures, LLC Mrs. Elaine R. Cullen Mr. and Mrs. Harry H. Cullen, Jr. The Cullen Trust for Health Care Mr. Milburn Eugene Cummins Ms. Ouida F. Cunningham The Harriet M. Cunningham Foundation Mr. and Mrs. Robert A. Curley, Jr. Dr. Veronica Curran and Mr. Michael Curran Mr. Jack T. Currie The Currie Fund Mr. and Mrs. Jim C. Curry Mr. and Mrs. Robert C. Curtis Mrs. Ruth Curtis and Family Curtis & Son Vacuum Service, Inc. Mr. and Mrs. Paul S. Curtiss Christy and Lou Cushman Dr. and Mrs. S. Marshall Cushman, Jr. Cutaneous Lymphoma Foundation Cyclists from Pro Peloton Bike Shop of Boulder, Colorado in memory of Bernie Lieff Cystic Fibrosis Foundation Cytogen Corporation D3 Foundation Dadeks Machine Works Corp. Mr. William P. Dahlquist Dako Dale Resources II, LLC The Dallas Foundation Dallas Jewish Community Foundation Mrs. Hazel E. Dalton Mrs. William E. Dalton Mr. Dan Daly Mr. Francis R. Daly The Dana Foundation L. B. Danford Charitable Trust Mr. Richard Dangelmayr Mr. and Mrs. Frank Daniel Ms. Barbara F. Daniel-Hetherington and Mr. Bob Hetherington Mr. and Mrs. James D. Dannenbaum Danny’s Asphalt Paving, Inc. Brit and Geryl Darington Mr. and Mrs. Charles G. Darnell, Jr. Mrs. Charline Dauphin The Sidney and Charline Dauphin Foundation Mr. and Mrs. Robert M. Davenport Mr. Robert M. Davey Mr. Solomon D. David, Jr. Mr. and Mrs. Eric Davidofsky Mr. and Mrs. Bruce G. Davidson Ken and Jimi Davidson Mr. and Mrs. Ralph H. Davidson Mrs. Ralph P. Davidson Estate of Robert V. Davidson The M. N. Davidson Foundation Mr. George H. Davis Estate of Ira Winfield Davis Mr. and Mrs. Jesse M. Davis Mr. Kenneth W. Davis, Jr. Mr. and Mrs. Lee H. Davis Mr. and Mrs. Leon Davis Mr. and Mrs. Mark L. Davis Mr. and Mrs. Ted E. Davis Mr. Tim Davis Mr. and Mrs. W. I. Davis, Jr.

The Charles & Melissa Davis Foundation Sam & Freda Davis Charitable Trust Davis-Lynch, Inc. Mr. and Mrs. Decker Dawson Mr. and Mrs. Robert S. Dayton Dayton Foundation Depository Inc. Dayton-Phoenix Group, Inc. De Leon Middle School Mr. and Mrs. Charles A. Dean Mr. and Mrs. Henry C. Dean Ms. Rhonda B. Dean and Dr. Michael S. Pad Mrs. Rosalie Dean Dr. and Mrs. Steven Dean Mr. and Mrs. Rutledge H. Deas, Jr. Mr. and Mrs. Switzer L. Deason Mr. and Mrs. Chad C. Deaton Mr. and Ms. Ronald R. DeBruin Ms. JoAnn DeCesaris The Geaton and JoAnn DeCesaris Family Foundation Mrs. Jean E. DeCicco Mrs. Elizabeth A. Decker Mr. and Mrs. Michael W. Deeds Mr. Brad G. Defenbaugh Bill and Carolyn Deffebach Mr. Gary D. DeFord Dr. and Mrs. Ralph DeFronzo Mr. and Mrs. Mike DeGeurin Ms. Christina DeIasi and Dr. Paul I. Howard Deibel Companies, Inc. Mrs. Linnet F. Deily Rafael del Barrio Dr. Jocelyn del Carmen Mr. Joseph Delahoussaye, Jr. Andrew Delaney Foundation Mr. and Mrs. Edward J. Delatte, Jr. Dr. and Mrs. Lance A. Dell Mr. and Mrs. Michael S. Dell The Michael and Susan Dell Foundation Dell Inc. Employees of Dell, Inc. Delta Delta Delta Northwest Harris County Alumnae Chapter Dr. and Mrs. Peter J. Dempsey Mr. and Mrs. William A. Denk Denman/Newman Foundation Mrs. Janie L. Denmon Dent Express Plus Dent-Ology Inc. Mrs. Katherine Denton Ms. Gabrielle I. Dentraygues Denver Foundation DePuy Spine Mrs. Charlotte J. Der Garry Mr. and Mrs. Conrad J. Derdeyn Dernick Resources, Inc. Mr. and Mrs. Brian DeRoeck The Walter DeRoeck Family Mr. and Mrs. Roland L. DesRoches, Jr. Estate of Bernard W. Detlefsen Deutsche Bank Americas Foundation Mr. and Mrs. Jerry H. Deutser Mr. and Mrs. Robert I. Deutser Ms. Pat Dever Mr. and Mrs. Robert L. Dewar Mrs. Jeanette G. DeZern Mr. Ugo di Portanova DialAmerica, Inc. Mr. and Mrs. George Diamantis Ms. Allyson Dias The Allyson K. Dias Foundation Tom and Kathy DiCenso Mr. Ronald J. Dickens Mr. and Mrs. John R. Dickerson Mrs. Lee A. Dickerson Mr. Ernest J. Dickinson Mr. and Mrs. Chester E. Dickson Mr. and Mrs. John P. Dieter Mr. and Mrs. Timothy W. Dietrich

Mr. and Mrs. W. Paul Dillard, Jr. Mr. Perry A. Dillon, Jr. Mr. and Mrs. Jack Dinerstein Mr. and Mrs. Ted H. Dinerstein The Dintersmith-Hazard Foundation Fund at the Boston Foundation Direct Success, Inc. Discovery Toys, Inc. Shanon and Lori DiSorbo Divas For A Cure Dr. and Mrs. Austin L. Dixon Dixon Family Foundation DKG Foundation Mr. and Mrs. Hugh C. Dobbins Ms. Deborah K. Dobbs Mr. Randall W. Dobbs Dr. and Mrs. Gerald D. Dodd, Jr. The Dodge Jones Foundation Mr. and Mrs. Edward D. Doherty II Mr. and Mrs. Edward P. Doherty Mr. Leland A. Dolan Mr. and Mrs. Michael Dolan Mrs. Beverly Dolinsky Mr. and Mrs. Edward Domingues Don Dickerson, Inc. Mr. and Mrs. Bill D. Donaldson Donne Di Domani Mr. and Mrs. Ben A. Donnell Nina H. Donnelley Mr. Thomas A. Donnick Mr. and Mrs. Jeffery D. Dooley Dr. Harold C. Dorin Mr. and Mrs. Benjamin L. Doskocil Mr. and Mrs. Sam P. Douglass Mr. Ward Dow The Dow Chemical Company Mrs. V. Benner Dowe Ms. Linda L. Downey Downey McGrath Group, Inc. Downman Family Foundation Mr. and Mrs. Robert J. Doyle Mr. and Mrs. William E. Dozier DPT Laboratories W. Russell and Vicki W. Drake Estate of Elizabeth E. Draper Mr. and Mrs. Harold M. Draughon Mr. and Mrs. Tommy J. Drescher Mr. and Mrs. Patrick D. Drew II Ms. Charlotte E. Driebe D’Sirbyrnes, LLC Alfonso and Mary Young Duarte Mr. and Mrs. Melvin Dube Oscar and Loretta Dube Mr. and Mrs. Fritz L. Duda Duda Family Foundation Mr. and Mrs. Robert L. Dudzik Mr. Robert Dueease Mr. and Mrs. Fred F. Dueser Mr. and Mrs. Dubb Duff Mr. and Mrs. Edward F. Duffy Doris Duke Charitable Foundation Duke Energy Foundation Estate of Jeannette Dulin Mr. and Mrs. Baxter W. Dunagan, Sr. Ms. Kathleen Dunagan Dunagan Farms, Ltd. Ms. Kathy R. Dunaway Mr. Donald G. Dunbar, Jr. Bob and Patty Duncan and Family Mr. and Mrs. Dan L. Duncan Jeaneane B. Duncan Mr. and Mrs. John H. Duncan, Sr. Mr. and Mrs. William G. Duncan Duncan & Boyd of San Antonio The Duncan Family Mr. and Mrs. Archie W. Dunham The Honorable and Mrs. Caswell J. Dunlap Mr. W. Greg Dunlevy Mr. and Mrs. M. Douglas Dunn Mr. W. Byron Dunn John S. Dunn Research Foundation

M. D. Anderson Annual Report 2007-2008 Mr. and Mrs. W. McComb Dunwoody Mr. and Mrs. Brad Duphorne Mr. and Mrs. Glenn L. Duphorne Mr. and Mrs. John L. Dupre III Mr. and Mrs. M. J. Dupuy Dr. and Mrs. Leonel D. Durbin Mr. and Mrs. Herman J. Durrett, Sr. DVJ Partnership Mr. and Mrs. Pete Dye Mr. and Mrs. Joe R. Dyer Mrs. Lois W. Dyk Mr. and Mrs. Gregory B. Dykes Dynamic Color Solutions Mr. and Mrs. Ralph Eads III Mr. and Mrs. John R. Eagle Mr. and Mrs. Robert W. Eagle E.A.G.L.E.S. Inc. Mr. Norm Eagleton Mr. and Mrs. Stephen D. Eakin Mr. and Mrs. Michael R. Earthman The Earthman Foundation Mr. and Mrs. Jerry T. Eason East Tennessee Foundation East Texas Communities Foundation Mr. Larry D. Eastepp Mr. and Mrs. J. Brandon Easterling Eastex Detachment Marine Corps League Mr. and Mrs. Gerald L. Eastham Mr. and Mrs. S. Stacy Eastland Mr. and Mrs. Robert Eaves EBAA Iron Sales, Inc. Mr. and Ms. Alfred H. Ebert, Jr. Mrs. Eleanor Ebner Mr. and Mrs. Jack P. Eckels Mr. and Mrs. Raymond A. Eckstein, Jr. Raymond A. Jr. and Roslyn S. Eckstein Foundation Mr. and Mrs. Robert L. Edenbaum Ms. Treca K. Edington Mr. William D. Edman Mr. and Mrs. Jack B. Edrington EDS, an HP Company Education Outcomes Science Edward P. Evans Foundation Mr. Jeffrey Edwards Mr. and Mrs. Ray W. Edwards Mrs. Virginia L. Edwards Mr. and Mrs. Robert B. Egan Egyptian Cultural & Educational Bureau Eisai Inc. Mr. Pete Eischen Mrs. Beverly B. Eisenberg Mr. and Mrs. Jay S. Eisenberg Mrs. M. Louise Eisworth Ms. Joyce H. Eiszner Eiszner Family Foundation Mr. Robert H. Eklund El Paso Corporation Mr. and Mrs. Phillip O. Elbert Elgin Breeding Service, Inc. Eli Lilly and Company Eli Lilly and Company Foundation Mr. and Mrs. John W. Elias Eliason Foundation Ella S.A. Contracting, LP Dr. Allen J. Ellender, Jr. Mr. and Mrs. George M. J. Elliott Mr. and Mrs. James E. Elliott Dr. David S. Ellis Mrs. Elnor S. Ellis Mr. and Mrs. Floyd E. Ellis Mr. and Mrs. James B. Ellis II The Ellwood Foundation Mr. and Mrs. Howard Elsberry Elsberry Family Foundation Elsevier, Inc. Dr. M. K. El-Yousef Embryon, Inc. EMD Chemicals Inc. Mr. and Mrs. William O. Emde

Endowed distinguished professorships* Abell-Hanger Foundation Distinguished Professorship

Helen Shafer Fly Distinguished Professorship of Anesthesiology in Honor of Bertha Davis-Clark, M.D.

Merrick L. Ross, M.D.

Sophie Caroline Steves Distinguished Professorship in Cancer Research

Bettyann Asche Murray Distinguished Professorship in Ovarian Cancer Research

Walter N. Hittelman, Ph.D.

Anil K. Sood, M.D.

Robert S. Benjamin, M.D.

Gloria Lupton Tennison Distinguished Professorship in Lung Cancer research

Barnts Family Distinguished Professorship in Cancer Research

Birdie J. and Lydia J. Resoft Distinguished Professorship in Gastrointestinal Oncology

Ritsuko Komaki, M.D.

Maria E. Suarez-Almazor, M.D.

Edward Rotan Distinguished Professorship in Cancer Research

Hubert L. and Olive Stringer Distinguished Professorship in Cancer Research

Jonas S. Almeida, Ph.D.

Thomas W. Feeley, M.D.

Annie Laurie Howard research Distinguished Professorship

Christopher I. Amos, Ph.D. P. H. and Fay E. Robinson Distinguished Professorship in Cancer Research

Robert S. Bresalier, M.D. H. Grant Taylor, M.D., W. W. Sutow, M.D., and Margaret P. Sullivan, M.D., Distinguished Professorship in Pediatrics

Laurence J.N. Cooper, M.D., Ph.D. Clifton D. Howe Distinguished Professorship in Pulmonary Medicine

Burton F. Dickey, M.D. Monteleone Family Foundation Distinguished Professorship for Research of Bladder and Kidney Cancers

Colin P. N. Dinney, M.D.

John Edward Simon Durham Ladbury, Ph.D.

Randal S. Weber, M.D.

Virginia H. Cockrell Distinguished Professorship in Immunology

Ruby E. Rutherford Distinguished Professorship

Jeffrey J. Molldrem, M.D.

Miles F. Wilkinson, Ph.D.

Robert R. Herring Distinguished Professorship in Clinical Research

Grady F. Saunders, Ph.D., Distinguished Professorship For Molecular Biology

Peter Mueller, Ph.D.

Richard D. Wood, Ph.D.

N. G. and Helen T. Hawkins Distinguished Professorship for Cancer Research

Hui-Lin Pan, M.D., Ph.D.

Nylene Eckles Distinguished Professorship in Breast Cancer Research

James E. Anderson Distinguished Professorship in Nuclear Medicine

*As of February 2009

Donald A. Podoloff, M.D.

Emerson Electric Company Mr. Leonard E. Emge Empire Truck Lines Inc. EnCana Cares (USA) Foundation Encore Acquisition Company Endo Pharmaceuticals Inc. Enduring Resources Energen Resources Corporation Energy Partners, Ltd. Energy XXI EnergyQuest II, LLC EnerVest Ltd. Engineered Air Balance Company, Inc. Mr. and Mrs. Randy R. Engstrom Entergy Charitable Foundation Entergy Services Entertainment Industry Foundation’s National Colorectal Cancer Research Alliance Enzon Pharmaceuticals Inc. EOG Resources EPIC Merchant Energy, LP Episcopal High School Mr. and Mrs. Mark J. Epley Equipment Leasing and Finance Association, Inc. Equisales Associates, Inc. Equus Media Development Company ERBE USA Incorporated Mr. Robert M. Erbrick, Sr. Mr. and Mrs. Harold J. Erbs Mr. Bruce R. Erickson Ms. Candas A. Erickson The Erie Community Foundation Mr. and Mrs. Sheldon R. Erikson Esenjay Petroleum Corporation Estate Planning Council of Louisville Mr. and Mrs. Wilmot J. Estes Mr. Rojelio Estrada

Charles M. McBride Distinguished Professorship in Surgical Oncology

The Honorable and Mrs. Melvyn J. Estrin Ethicon Endo-Surgery, Inc. Ethicon, Inc. Mrs. Ann A. Eutsler Mr. and Mrs. Bruce Evans Mr. Edward P. Evans Mr. Loyd H. Evans, Jr. Mr. Mark Evans Mr. Roy G. Evans Ms. Susannah S. Evans Mr. and Mrs. Wendall C. Evans Ms. Zora Evans Mr. and Mrs. Carl B. Everett III Excalibar Minerals Inc. EXCO Resources, Inc. The Exilarch’s Foundation ExxonMobil and ExxonMobil Foundation Mr. and Mrs. Douglas K. Eyberg Mr. and Mrs. Simon B. Eyles Mr. Howard Doc Ezell Fabenco Founding Fathers Foundation The R. W. Fair Foundation Faith Family & Friends/Michael and Kristine Nolan Ms. Patrice Falagrady and Mr. William Young Patty and Larry Fallek Jana and Richard Fant Diane Lokey Farb in honor of Harold Farb Harold Farb Foundation Mr. Kenneth K. Farmer Mr. and Mrs. Richard T. Farmer The Farmer Family Foundation Mr. Douglas Farnie Mr. Thomas G. Farrier Mr. and Mrs. G. Steven Farris Mr. and Mrs. David S. Fast

Dihua Yu, M.D., Ph.D.

Mrs. Jane E. Fatino Ms. Betty J. Faulkner Mrs. Carolyn Grant Fay F.C. Designs, Inc. Fee, Smith, Sharp & Vitullo, LLP Mr. I. N. Fehr Mr. and Mrs. Hill A. Feinberg Feinberg Foundation Inc. Mrs. Bernice R. Feld Mr. John Feldsien Mrs. Ouida W. Felker Ms. Magda Felsbourg and Mr. Frederik G. Van de Mortel Mr. and Mrs. Dillon J. Ferguson Mr. Randy R. Fern Mrs. Emelina Fernandez Mr. and Mrs. Lazaro H. Fernandez Mr. and Mrs. Louis J. Fernandez, Jr. Mr. and Mrs. Luis Fernandez Mr. Robert A. Fernandez Mr. and Mrs. Frank Ferreira Mr. Melvin J. Ferreira Dr. and Mrs. Ralph T. Ferrell Mr. Thomas E. Ferrill, Sr. Mr. and Mrs. Chris F. Fette Mr. and Mrs. George H. Fibbe Mr. John L. Fichter Fidelity Investments Field & Stream Bowhunters Ms. Allie Fields Mr. Bert Fields, Jr. Dr. Tina T. Fields Mr. and Mrs. Brian M. Fife Mr. James A. Fife and Family Ms. Ann R. Figg Filipow Associates Ms. Kari E. Findley and Mr. Ken I. Sill Mr. and Mrs. Perry Fine Mr. and Mrs. Jerry E. Finger Linda K. Finger

Mr. and Mrs. Marvy A. Finger Mr. Rodney S. Finger Jerry and Nanette Finger Foundation Linda and Ronny Finger Foundation Marvy Finger Family Foundation Finger Furniture Company, Inc. Finish Line Sports Mr. and Mrs. Alan Jonathan Finlay Mrs. Mary Ellen Finnegan Mr. and Mrs. Joseph J. Firestone First Financial Bank of Eastland First National Bank of Albany/ Breckenridge First National Bank of Bastrop, Elgin, Smithville First National Bank of Giddings Ray C. Fish Foundation Mr. and Mrs. Gregory J. Fisher Mr. and Mrs. Robert B. Fisher, Jr. Mr. Larry Fishman Mr. and Mrs. George R. Fister Ms. Melba Fitzgerald David and Judy Fleischer Mr. and Mrs. Morton H. Fleischer The Fleischer Foundation Ms. Lynda C. Fleming Flight Attendant Medical Research Institute Mr. Joseph H. Flom Floors Inc. Mrs. Harriet H. Flora Cherie and Jim Flores Dr. and Mrs. Hildegardo E. Flores Florida Hospital Medical Center Estate of St. Marc J. Flotte Mrs. Patricia L. Flower Mr. and Mrs. Kenneth A. Floyd Mr. Robert C. Floyd Sharon and Bobby Floyd Mr. and Mrs. Patrick J. Flynn Mr. Don W. Flynt 77

Partners in Making Cancer History® Endowed professorships* Doctor R. Lee Clark Professorship

Bessie McGoldrick Professorship in Clinical Cancer research

Helen Buchanan and Stanley Joseph Seeger Research Professorship

Jean-Pierre Issa, M.D.

Renata Pasqualini, Ph.D.

Bharat B. Aggarwal, Ph.D.

Felix Haas Professorship in Basic Science

John Q. Gaines Foundation Professorship for Cancer Research

Hubert L. and Olive Stringer Professorship for Cancer Treatment and Research

Marcus T. Kuo, Ph.D.

Alan J. Schroit, Ph.D.

Elza A. and Ina Shackelford Freeman Endowed Professorship in Lung Cancer

Robert F. Fly Professorship of Surgical Oncology, in honor of R. lee clark, m.d.

Wadih Arap, M.D., Ph.D.

Jonathan Kurie, M.D.

Stephen G. Swisher, M.D.

Ashbel Smith Professorship

H-e-b Professorship in Research

Anise J. Sorrell Professorship

Menashe Bar-Eli, Ph.D.

Karen H. Lu, M.D.

Peter F. Thall, Ph.D.

McCullough Professorship for Cancer Research

Florence Maude Thomas Cancer Research Professorship

Mattie Allen Fair Professorship in Cancer Research

Charles Cleeland, Ph.D.

Marvin L. Meistrich, Ph.D.

Elizabeth L. Travis, Ph.D.

Kenneth D. Muller Professorship in Melanoma Research

Kathryn O’Connor Research Professorship

Dallas/Fort Worth Living Legend Professorship

Adel K. El-Naggar, M.D., Ph.D.

Raymond E. Meyn Jr., Ph.D.

Stephen E. Ullrich, Ph.D.

Ashbel Smith Professorship

United Energy Resources Inc. Professorship

Ruth and Walter Sterling Professorship

Christian R. Abee, D.V.M. Ransom Horne, Jr. Professorship for Cancer Research

Varsha Gandhi, Ph.D.

Luka Milas, M.D., Ph.D.

Ashbel Smith Professorship

Bonnie S. Glisson, M.D. Frances King Black Memorial Professorship for Cancer Research

Ashbel Smith Professorship

A Conversation with a Living Legend Professorship

Jeffrey N. Myers, M.D., Ph.D.

Edward T.H. Yeh, M.D.

Elizabeth A. Grimm, Ph.D. FMC Technologies Matching Gift Program Ms. Carolyn E. Fogg Mr. Raymond Fonk Dr. and Mrs. Ramon L. Font Dr. Susan Foote and Mr. Stephen L. Feinberg Sylvia and Bill Foran Mr. and Mrs. Eric A. Ford Mr. Walter O. Ford, Jr. Mr. and Mrs. Martin H. Forman Mr. and Mrs. Bill Forney, Jr. Ms. Tracy J. Forrest Mr. Brad Forrester Mr. Richard W. Forsythe Mr. and Mrs. John F. Fort III Fort Bend Independent School District Mr. James R. Foster Mr. and Mrs. Joe B. Foster Mr. Michael L. Foster Foster Foundation, Incorporated Mr. and Mrs. David C. Foulk The Foundation For A Second Chance Foundation for Anesthesia Education and Research Foundation for the Carolinas Foundation For Thymic Cancer Research Four Seasons Landscaping, Inc. Mr. Greg Fourticq, Jr. Patsy and Greg Fourticq Dr. Sandra Fowler and Mr. Earl Fowler Mr. G. Douglas Fox Mr. and Mrs. R. Alan Fox Mr. and Mrs. Steve L. Fox Mr. and Mrs. Kevin Lee Foxx Mrs. Martha O. Foy Mr. and Mrs. Michael S. Francisco Mr. and Mrs. Gregory Franckowiak Mr. and Mrs. Charles M. Francois Mr. Kevin Frankel Jimmy Franklin 78

Cheryl L. Walker, Ph.D.

Mrs. Roberta Franklin E. A. Franklin Charitable Trust, Giles C. McCrary, Admin. Gerald and Roberta Franklin Charitable Foundation Frank’s International Mr. and Mrs. Fred Frantz Mr. and Mrs. Gregory R. Frazier Mr. Lorn Frazier Mrs. Margaret J. Frazier Mr. and Mrs. Michael E. Frazier Robert Bevis Frazier PTO Mr. and Mrs. Norman D. Frede George and Marguarette Frederick Mr. and Mrs. Robert J. Fredrikson Twilight and Marc Freedman Foundation Mr. Bradford M. Freeman Estate of E. A. Freeman Ms. Phyllis R. Freeman Mrs. Sigrid Freeman-Bonner Freeport-McMoRan Copper & Gold Foundation Freeport-McMoRan Foundation Mr. and Mrs. Dale G. French Mr. and Mrs. Albert E. Fridkin Mrs. Carolyn U. Fridley Friedkin Business Services Mrs. Fay Cohen Friedman Mr. and Mrs. Harold Friedman Mr. and Mrs. Joseph A. Friedman Frog Works Inc. Mr. Richard Fromdahl Frontier Bank of Texas Ms. Porcha R. Frost Frost Bank The Fruehauf Foundation Ms. Shara M. Fryer and Mr. Barry Silverman Fugro, Inc. Fulbright & Jaworski L.L.P. Dr. and Mrs. Clay W. G. Fulcher Mr. and Mrs. Craig L. Fuller Mr. and Mrs. John Frank Fuller

*As of February 2009

Mrs. Patricia H. Fuller Mr. and Mrs. Victor L. Fuller Ms. Jeffrie Fulmer-Thomas and Mr. Terry L. Thomas Mr. and Mrs. Steven L. Fulton Mr. and Mrs. James M. Funk Mr. and Mrs. James F. Furr Dr. Kenneth D. Futch Future Petroleum Company, LLC Estate of Frank H. Gabriel Mrs. Carol J. Gagnon Mr. and Mrs. Frank R. Gailor Mr. and Mrs. Melvyn P. Galin Galin Family Foundation Mr. and Mrs. Mike Gallagher Parents of Kevin M. Gallagher Mrs. Lois I. Galloway Mr. and Mrs. Barry J. Galt Mr. and Mrs. Michael P. Galvin Mr. and Mrs. Raymond E. Galvin Dorothy & Ray Galvin Foundation, Inc. Mr. and Mrs. John A. Gambell Mr. and Mrs. Michael Gamson Mr. and Mrs. Steven J. Gangelhoff, Sr. Gannett Foundation Mr. and Mrs. Robert A. Gardner, Jr. Mr. and Mrs. Ronald Garfield Garfield & Hecht, P. C. Mrs. Wanda M. Garner Mr. and Mrs. Michael J. Garrett Mr. and Mrs. J. H. Garrison Mr. James R. Garrison Mr. and Mrs. Kenneth N. Garrison Carol and Gary Gartsman Mr. C. Michael Garver The Honorable and Mrs. William L. Garwood Mrs. Barbara P. Gary Mr. Thomas E. Gary Gary DeFord Investments Ms. Rene Garza Mr. and Mrs. Severiano A. Garza

Mr. Norman J. Gassett Gateway for Cancer Research Mr. and Mrs. Mike Gatewood The Gatewood Family Foundation Dr. Polly K. Gauthier and Dr. Jerry W. Gauthier Mr. and Mrs. Gibson Gayle, Jr. GE Foundation GE Medical Systems Mr. and Mrs. C. P. Geary, Jr. Mr. and Mrs. Robert T. Gebert Estate of Louis J. Gehrm Mr. and Mrs. Douglas B. Gehrman The Honorable and Mrs. Bruce S. Gelb Lawrence M. Gelb Foundation Inc. Mr. and Mrs. William P. Gendron Genentech, BioOncology General Motors Corporation Estate of Charles Genite, Jr. Genomic Health, Inc. Dr. Donald C. Gentry Genzyme Corporation Mr. and Mrs. R. James George, Jr. George Tulipana Jr. Memorial Golf Tournament Mr. and Mrs. Kenneth T. Gerew Mr. and Mrs. Daniel J. Gerhardt Estate of Taylor B. Gerke Mr. and Mrs. Richard H. Gerlach Mr. Glenn R. Gerloff and Mrs. Joan L. Pace-Gerloff Estate of Frances A. Gershon Mr. and Mrs. Fred Gerth Mr. and Mrs. Solomon Getz GFWC Woman’s Wednesday Club of Granbury Dr. Shubhra Ghosh Dr. Marc Ghysels Beth and Wayne Gibbens Mr. and Mrs. James A. Gibbs Mr. and Mrs. Robin C. Gibbs Mr. and Mrs. Gary F. Gibson Mr. and Mrs. Shane M. Gibson

Mr. and Mrs. McHenry Giffin, Jr. Mr. and Mrs. Robert R. Gignac Ms. Laura S. Gilbert Mr. and Mrs. Norman Gilbert Gilead Sciences, Inc. Mr. and Mrs. James D. Giles Terry M. Giles and Kalli S. O’Malley Ms. Deborah J. Gillen The Gillette Company Mr. Jack D. Gillis Mr. and Mrs. Gary C. Gilmer Estates of L. B. and Edna E. Gilpin Mr. and Mrs. Douglas L. Gilstrap Estate of Mose A. Gimbel, Jr. Ms. Frances E. Ginsburg Mrs. Jeanette M. Ginsburg GivingExpress Program from American Express Mr. Joseph G. Gladbach Gladder’s Gourmet Cookies Mr. and Mrs. Thomas S. Glanville Mr. and Mrs. John D. Glass, Jr. Mr. Robert Q. Glass III Glass Solutions Dr. and Mrs. Armand B. Glassman glassybaby LLC GlaxoSmithKline Mr. William T. Gleason, Jr. Glendale Boat Works, Inc. Mr. and Mrs. Rex K. Glendenning Ms. Susan G. Glesby Mr. and Mrs. Lanny Glick Mr. and Mrs. Donald Glickman Estate of Royce A. Glidden Globus Medical, Inc. Mr. and Mrs. Michael J. Glosserman Gloucester Pharmaceuticals, Inc. Ms. Peggy Glover Charles B. Goddard Foundation Dr. Helmuth Goepfert Dr. and Mrs. Glenn A. Goerke Mrs. Quay B. Goff Mr. and Mrs. Victor Golat Kelly Golat Melanoma Research Scholarship Fund Inc. Mrs. Carol S. Gold Mr. and Mrs. Frank S. Goldberg Mr. and Mrs. Lance Goldberg Dr. Seymour H. Goldberg Mr. and Mrs. Robert D. Goldberger Miss Kelly Golden Linda and Ray Golden The Goldhirsh Foundation Goldman Sachs Philanthropy Fund Goldman, Sachs & Co. Mr. and Mrs. James D. Goldston III Golfers Against Cancer, Inc. Mr. and Mrs. Stephen H. Golub Ms. Carol R. Golubock and Mr. Arthur R. Watson Ms. Andrea D. Gonzalez Ms. Jeanie C. Gonzalez Mrs. Nancy C. Good Mr. and Mrs. Samuel E. Good Mr. and Mrs. John Goodale Mr. and Mrs. Al J. Goodman The Honorable and Mrs. Roy M. Goodman Mr. Scott Kean Goodman Mr. and Mrs. Donald Goodwin Mr. and Mrs. William H. Goodwin, Jr. Ms. Dorothy M. Goodykoontz Mrs. Aileen Becker Gordon Mr. Steven L. Gordon Mr. and Mrs. John H. Gorrell Mr. Joaquin Gortari Mr. and Mrs. Thomas H. Gose Mrs. Cora L. Gott Mr. and Mrs. Robert J. Gottschalk Mr. Keith Graff Dr. and Mrs. Charles W. Graham Mrs. Donna A. Graham

M. D. Anderson Annual Report 2007-2008 Mr. and Mrs. Robert H. Graham Graham Brothers Partnership Grand Chapter of Texas Order of the Eastern Star Mr. and Mrs. Colin J. Grant Mr. and Mrs. Gary D. Grant Dr. and Mrs. Joseph M. Grant Grant Prideco, Inc. Mr. Mario Grauso Mr. and Mrs. Andrew E. Graves Mrs. Ann Graves Mr. James C. Graves Mr. and Mrs. Jo A. Graves Mr. and Mrs. Robert R. Graves Mrs. Cherry K. Gray Mr. David E. Gray Mr. Ed T. Gray Ms. Emma D. Gray Mrs. Helen S. Gray Mr. Richard W. Gray III Estate of Roger K. Gray Greater Houston Community Foundation Mr. and Mrs. Michael J. Greathead Ms. Callie B. Green Mr. and Mrs. Curtis S. Green Mrs. Marianne W. Green Mr. and Mrs. Jim Greene Mr. and Mrs. John J. Greene Mrs. Joyce B. Greene Mr. and Mrs. Michael S. Greene Mr. Edwin F. Greenlee Debra and Mark Gregg Mr. and Mrs. Gaynor G. Gremillion Melissa Josey Gribble Mr. and Mrs. Dale Grider Mr. and Mrs. F. O’Neil Griffin Mr. and Mrs. Harold M. Griffin Mr. and Mrs. James Griffin Mr. and Mrs. John I. Griffin Mr. Leroy B. Griffin Mr. and Mrs. Robert M. Griffin The Neil and Elaine Griffin Foundation Mr. and Mrs. Guy W. Griggs Mr. and Mrs. H. James Griggs Mr. and Mrs. Keith M. Griggs Dr. and Mrs. Karolos Grigoriadis Mr. and Mrs. David M. Grimes II Mr. and Mrs. David M. Grimes, Sr. Mr. Robert Grimes Grimes Energy Company Mr. and Mrs. Robert H. Grimmer Mr. and Mrs. W. David Grindle Mr. Tevis Grinstead and Ms. Marilee Wood Mr. and Mrs. George E. Grobowsky Mr. and Mrs. James A. Grogan Mr. and Mrs. Roy J. Grogan Mr. and Mrs. F. Scott Gross Mr. and Mrs. Jenard M. Gross Mr. Ross Grossman Ms. Sandra D. Grossman Mr. and Mrs. Stuart Grossman The Grossman Foundation Mr. and Mrs. Arden R. Grover Mr. and Mrs. Frank R. Groves, Jr. Mrs. Helen K. Groves Mr. Randy J. Groves Mr. Bryan D. Grundhoefer Mr. Larry D. Gryder GSL Constructors, Ltd. Mr. Guillermo Guefen Ms. Marilyn Nuccio Guercio Mr. and Mrs. A. R. “Felo” Guerra Mr. and Mrs. Francisco J. Guerra, Jr. Guerra Bros. Successors Mrs. Sandee Guevremont Dr. and Mrs. Joseph J. Gugenheim, Jr. Ms. Hillary A. Guild Mr. and Mrs. Ben A. Guill Mrs. Hennen F. Guinn

Gulf Coast Asphalt Company, L.L.C. Gulf Coast Mounted Shooters Gulf-Tex Co., Inc. The Gumbo Foundation Ms. Janet Gurwitch Dr. Robert E. Gustafson Gynecologic Cancer Foundation Estate of Mildred G. Haas Mr. and Mrs. Sam Hachem Mr. and Mrs. Kirk S. Hachigian Dr. Carin Hagberg and Mr. Steven L. Roberts J. M. Haggar, Jr. Family Foundation Mrs. Inda D. Hahn Mr. and Mrs. Thomas C. Halbouty Mr. and Mrs. Rodney L. Hale Mr. and Mrs. James E. Haley Mrs. Shirley J. Halff Mr. and Mrs. Charles W. Hall Mr. and Mrs. James E. Hall Mr. and Mrs. Luke Hall III Mr. and Mrs. Oren M. Hall Ms. Patricia S. Hall Mr. and Mrs. Warren W. Hall Mr. and Mrs. Willie M. Hall Mr. and Mrs. Albert Hallford Employees of Halliburton Halliburton Company Halliburton Foundation, Inc. Mr. Frank M. Hallinan Halo Lee Wayne Mr. and Mrs. Richard C. Halpern The Hamill Foundation Mr. John S. Hamilton Mr. and Mrs. O. C. Hamilton, Jr. Mr. and Mrs. Jerrol D. Hamlin Mr. John J. Hamlin and Ms. Nancy G. Robinett Mrs. Nancy J. Hamm Mr. R. Hamm The Nancy and Alan Hamm Charitable Foundation, Inc. Mr. J. Kenneth Hanak Ms. Irene S. Haney Mr. and Mrs. Raymond E. Hankamer, Sr. Ms. Betty Lou Hanlon Ms. Margery L. Hanna Mr. Pete M. Hanna Mr. and Mrs. Robert C. Hanna Robert H. Hannifin and Maxine B. Hannifin Trust Mr. and Mrs. Clement E. Hanrahan Mrs. Polly H. Hansen Mr. Robert Hansen Mr. Wesley L. Hansen Dr. and Mrs. William F. Hanson Mrs. Helen C. Harbeson Mr. and Mrs. Richard L. Harbin Mr. and Mrs. Jan A. Harding John Charles Hardison Mr. and Mrs. John Hare Mr. O. O. Hare, Jr. Mr. and Mrs. Calvin Hargrave Mrs. Marion S. Hargrove Mr. and Mrs. Jay D. Harkins Harl and Billy Thomas Charolais, Inc. Mr. and Mrs. James B. Harlow Harmonious Housing Ms. Anne M. Harper Antony C. Harper Mr. and Mrs. Thomas R. Harper Harper and Pearson Company PC Harrigan Energy Partners, Inc. Cecily and Bob Harris Mr. Charles W. Harris Mrs. James B. Harris Ms. Margaret A. Harris Mr. and Mrs. Richard L. Harris Mr. and Mrs. Robert M. Harris Mr. Roy D. Harris Mr. Steven V. Harris Harris County Hospital District

Harris Foundation John E. and Dorothy J. Harris Family Foundation Mr. and Mrs. James B. Harrison Mr. and Mrs. Ken I. Harrison Mr. and Mrs. T. E. Harrod Harry J. Crouse Design, Inc. Mr. and Mrs. Robert N. Hart Mrs. Thomas F. Hart The Hart Charitable Trust Mr. Roy R. Hartmann Mr. and Mrs. Bill Hartung Mrs. John M. Hartwell Mr. and Mrs. Robert E. Harvey Mr. Will P. Harvey Mr. and Mrs. George R. Harvick The Hasey Foundation Mr. and Mrs. A. Hamid Hashemi Dr. Scott Hassell Mrs. Rhonda W. Hassenbusch Mr. and Mrs. Fred M. Haston, Jr. Mr. Neal C. Hasty Mr. Richard Hauptfleisch Mr. and Mrs. Edward B. Hauser Hawker Beechcraft Acquisition Company, LLC Mrs. Margaret D. Hawkins and Mr. Fred J. Redeker The Hawn Foundation, Inc. Mr. and Mrs. Dan P. Haworth Mrs. Janet Hayden Mr. Gary R. Hayes Mr. and Mrs. John E. Hayes, Jr. Mr. Charles H. Hayhurst Mrs. Betty J. Haynes Dr. Thomas P. Haynie Mrs. Dorothy C. Hays Mr. W. Gene Hays Mr. and Mrs. Johnny P. Hayter Mr. and Mrs. William A. Hazel Mr. Richard Head Head for the Cure Foundation Mr. and Mrs. Skip Healey Mr. and Mrs. Philip J. Heard Mr. Jeffrey Sean Hearne Heart of Georgia Insurance Brokers, Inc. Heart Sing Foundation Mr. and Mrs. Dennis Heath Mr. and Mrs. Richard W. Heath H-E-B Mr. and Mrs. Michael D. Hebert Mr. and Mrs. Virgil Hebert, Jr. Ms. Adrea D. Heebe and Mr. Dominick A Russo, Jr. Mr. and Mrs. James H. Hefner, Sr. Mr. and Mrs. Robert A. Hefner III Mrs. Carol M. Heidbreder Heidmar Inc. Mr. and Mrs. L. William Heiligbrodt Mr. and Mrs. Paul A. Heilman Ms. Barbara B. Heim Mr. and Mrs. Bradley V. Heiner Mr. and Mrs. Rodney R. Heisch Mr. and Mrs. Alan B. Helfman Mr. and Mrs. Jack S. Helfman Helfman River Oaks Chrysler Jeep Mr. and Mrs. Edwin Heller Estate of Gerald Henderson Mrs. Jeanette Henderson William G. Henderson and Janon Furlong Zordan Mr. and Mrs. Steven J. Hendrick Mr. Mark W. Hendricks Hendricks and Partners Mrs. Sherry L. Henk Mr. and Mrs. Bill Henn Mr. and Mrs. John W. Hennessey II Mr. and Mrs. Bill D. Henry Dr. and Mrs. Charles E. Henry Janis and Randy Henry Mr. John A. Henry Margaret Whelan Hensley

Mr. and Mrs. Louis R. Henson Hera Foundation Mr. and Mrs. Michael F. Herbel Mr. Bob L. Herd Bob L. Herd Foundation Dr. Carolyn Hernandez Mr. and Mrs. David T. Herr Mrs. Marjorie J. Herrero Mr. and Mrs. Marc Herzstein Mr. Max Herman Herzstein Max and Isabell Herzstein Foundation Mr. Robert M. Hess Mr. Daryl Hester Mr. Marvin H. Hester Ms. Kathy Hett Mr. and Mrs. Howard H. Hewitt Ms. Patricia Hewlett Hewlett-Packard Company Dr. and Mrs. Jack Heydemann Mr. Don Heyden Dr. and Mrs. John Victor Heymach Gloria and Ed Hicks Estate of Mary M. Hicks Hidden Pond Foundation Mr. and Mrs. Thomas L. High High Noon Construction, Inc. Higman Marine Services, Inc. Hilcorp Energy Company Mr. Brian Hill Miss Lyda Hill Mr. Melvin J. Hill Mr. and Mrs. Neil Hill Mr. and Mrs. Yerger Hill III Mr. and Mrs. David M. Hillberry The Hillcrest Foundation Mr. R. Glenn Hilliard Dr. and Mrs. Donald W. Hillman Hilltop Holdings Mrs. Mary S. Hinds Mrs. Renee L. Hinds Mr. Gilbert C. Hine Wendy and Jeff Hines Hines Ms. Toni Evans Hinkhouse Dr. Robert M. A. Hirschfeld Hitachi America Ltd. Mr. and Mrs. Brett Russell Hitt Mr. J. Charles Hitt Mrs. Mary Scott Hobdy Mr. and Mrs. H. M. Hochman Mr. Leland A. Hodges, Jr. Mr. and Mrs. Mark C. Hodges The Hodges Companies, Inc. Hodges Fund of the Community Foundation of North Texas Mr. and Mrs. Warren E. Hoeffner The Hoeffner Foundation Arlene and Marshall Hoffman Mr. and Mrs. Marshall Hoffman Mr. and Mrs. Raymond F. Hoffman Mr. and Mrs. Brian B. Hogan Mr. and Mrs. Dan Hogan III Mike Hogg Fund Mr. and Mrs. Forrest E. Hoglund The Hoglund Foundation Mr. and Ms. James T. Hoke, Jr. MaraLessa and Alter Holand Mr. and Mrs. Arthur S. Holden Don L. and Julie Holden Foundation Mr. and Mrs. Tim K. Holder Mr. and Mrs. John B. Holdsworth Mr. and Mrs. J. W. Holland Hollister Incorporated The Honorable and Mrs. Jess Holloway Katherine and Sam Holman Holt Atherton Educational Foundation, Inc. Home Asset, Inc. William E. and Audrine Honey Foundation, Inc.

Honeywell Foundation Dr. and Mrs. Waun Ki Hong Mr. Edgar M. Hood III Mr. and Mrs. Charles W. Hooper, Jr. Mr. and Mrs. Lindsay D. Hooper Mrs. Milton L. Hooper Mr. and Mrs. Alvin C. Hope, Jr. Hope on Wheels Hyundai Dealers Hope Street Kids Mr. Bob C. Hopkins Mr. and Mrs. David Hopkins The Joan B. Hornig Foundation Ms. Patricia R. Horton Mr. and Mrs. Richard J. Horvath Mr. Richard L. Hosea, Jr. Hostgator.com Hotel ZaZa Houston Museum District Mr. and Mrs. Glen Hou Mr. and Mrs. James Houston Houston Astros Baseball Club Houston Endowment Houston Fuel Oil Terminal Co. Houston Golf Association-Shell Houston Open Houston Jewish Community Foundation Houston Pi Beta Phi Foundation Mr. and Mrs. George M. Hover Mr. and Mrs. Hilton H. Howell, Jr. Mrs. Paul N. Howell Mr. and Mrs. Peter Paul Howell Robert and Catherine Howell Andrew and Ingrid Hoyle HRF Exploration & Production L.L.C. HTK Consultants, Inc. Mr. and Mrs. John D. Hubbard Mr. and Mrs. Dennis M. Hudson Mrs. Letha K. Hudson Mr. and Mrs. T. B. Hudson Mr. and Mrs. Bert L. Huebner Mr. and Mrs. Daniel W. Huff, Jr. The Honorable Roy M. Huffington Ms. Terry Huffington and Dr. Ralph Dittman Gail and Bob Hughes Mrs. Grace L. Hughes Mr. and Mrs. William T. Hughes Howard Hughes Medical Institute Hugins Construction Corporation Mr. and Mrs. David C. Hull, Jr. Mrs. Billie Hultgren Mr. and Mrs. Emmett A. Humble Ms. Belinda J. Humphrey Mr. and Mrs. Gene E. Humphrey Estate of Joyce M. Humrichouse Linda and Barry Hunsaker Mr. and Mrs. Hunter Hunt Mr. Thomas M. Hunt Mr. and Mrs. Todd M. Hunt Mr. and Mrs. Woody L. Hunt Hunt & Associates, Inc. Hunt Family Foundation Hunt Petroleum Corporation Mr. and Mrs. Robert C. Hunter The Hunton Group Dr. and Mrs. Robert B. Hurlbert Mr. and Mrs. Joel B. Hurley Mr. Kirby J. Hurley Roberta P. Hurst Mr. and Mrs. David A. Hurwich Mr. and Mrs. Charles E. Hurwitz Dr. and Mrs. Martin E. Hurwitz Ms. Patricia M. Hutcheson Ms. Nina C. Hutton Mrs. Mary E. Huxtable Mr. and Mrs. Harry J. Hyatt Mr. and Mrs. Justin J. Hyland Hyundai Motor America Hyundai of El Paso I Do Foundation Dr. and Mrs. Geoffrey S. Ibbott IBC Foundation 79

Partners in Making Cancer History® IBERDROLA RENEWABLES IBM IBM International Foundation Mr. Robert Ideus IDM, Inc. IDM Pharma Mr. and Mrs. Roberto J. Iglesias Mr. and Mrs. John S. Ikard Ikonisys, Inc. Illumina, Inc. Mrs. Barbara F. Immroth IMPAC Medical Systems, Inc. Indigo Minerals, LLC Indo-American Charity Foundation of Houston, Inc. Infinity Oil & Gas, Inc. InfuSystem Inc. Mr. and Mrs. James A. Ingram Mr. and Mrs. Donald E. Inman Inman Texas Company Insurance Alliance Foundation Insurance Network of Texas The Integer Group InterActive Health Care, Inc. International Atomic Energy Agency International Gas Consulting, Inc. International Myeloma Foundation International Society for Transgenic Technologies

Interquest Medical & Scientific Communications Intruder Alert Systems Invesco Aim Dr. Katie D. Irani iS Healthcare Dynamics Limited Mr. and Mrs. Robert Isaacs Ms. Charlene C. Isbell Mr. and Mrs. James A. Isbell IT Partners Charity Golf Event Mr. and Mrs. Robert W. Ivey J. D. Fields and Company Mr. and Mrs. Gerald Glenn Jackson Jack and Johnelle Jackson Mr. and Mrs. James M. Jackson Mr. and Mrs. John C. Jackson II Mr. and Mrs. John M. Jackson Mrs. Peggy D. Jackson Mr. and Mrs. Robert R. Jackson Jackson-Merkey Contractors, Inc. Mr. and Mrs. Charles E. Jacobs Mr. and Mrs. Joshua M. Jacobs The Charles E. Jacobs Foundation Mr. and Mrs. Gregg A. Jacobson Mr. and Mrs. A. J. Jacques The Rona Jaffe Foundation Dr. and Mrs. David G. Jaimovich Mr. and Mrs. J. E. Jalufka

The JAM Foundation Mr. Dan James Mr. and Mrs. Frank M. James James R. Roderick & Associates, Inc. Mrs. Diana K. Jameson Jane Phillips Society, The Woodlands Chapter Mr. and Mrs. Joel C. Jankowsky Joel and Carol Jankowsky Foundation Dr. and Mrs. Sam P. Javedan Dr. and Mrs. Thirumalairaj Jayakumar Mr. and Mrs. L. Weldon Jaynes Jefferies & Company, Inc. Mrs. Carol T. Jeffrey Mr. William R. Jeffryes Ms. Darla Jenkins Mr. and Mrs. Charles H. Jennings Mr. and Mrs. Gary L. Jennings Dr. Rebecca McGowen Jensen and Mr. Steve Baughman Jensen Mr. Vaughan Jensen Dr. and Mrs. Gaylord A. Jentz Mr. James A. Jernigan Jessi’s Jam Mr. George H. Jewell, Jr. Nancy Glanville Jewell Jewish Communal Fund The Jewish Community Federation of Cleveland

Advance Team 2008-2009 The following individuals compose a volunteer leadership board focused on advancing M. D. Anderson’s mission to eliminate cancer through community-based initiatives centered on basic science research, education and prevention of cancer. This year’s focus has been on the Children’s Cancer Hospital. Mrs. Melissa Amschwand Bellinger Mr. Brent Benoit Mr. Stuart Bernstein Mrs. Jenee Bobbora Mrs. Nancy Broudy Mrs. Amanda Bush Mr. Bill Campbell Mr. John B. Connally IV Mr. John Courtney Mrs. Andrea Crawmer Mrs. Katie Earthman Cullen Dr. Steven Dean Mrs. Shelly Dee Mr. G. Edward Deery Mrs. Jill Deutser Mrs. Courtney Duphorne Mrs. Leslie Easterling Mr. Jay Eisenberg Mrs. Jeannie Frazier Mrs. Leslie Swanson-Gallardo Mr. Elliot Goldman Ms. Carolyn Hansard Mr. R. Lee Harrell, Jr. Mr. Alan Helfman Ms. Lourdes Hernandez Mr. David Herr Mrs. Shawn Hogan Mr. Britton Holland Mrs. Beth Williams Lee Mrs. Ashley Loeffler

Mrs. Ann Lovasz Mr. Andrew McCullough, Jr. Mr. Connelly McGreevy Mrs. Clayton Maebius Mr. Eric Meadows Ms. Gloria Moncrief Mr. Brian Murphy Mrs. Camille Harrell Ohmstede Mrs. Kathy O’Neal Mrs. Dorothy Paterson Ms. Debra Paxton Mrs. Mary Martha Pickens Mr. Ian Radomski Mrs. Leslie Rainbolt Mrs. Sheryl Rapp Mr. Alan Rosen Mr. Jonathan Rosenthal Mrs. Anooshea Saberioon Taghdisi Mrs. Angela Schroder Mr. Chad Scott Mr. Roben Sellers Ms. Jennifer Shufelt Mr. John Styles, Jr. Mr. Ignacio Urbieta, Jr. Mr. Adalberto Vara Mr. Rad Weaver Mr. Temple Webber, III Mrs. Kathryn Hall Wilson Mr. Don Woo

Jewish Community Foundation of Broward County Jewish Federation of Metropolitan Chicago Jewish Federation of St. Louis Dr. Sao Jiralerspong Mrs. Helen A. Joffrion John A. Urquhart Associates John Eagle Dealerships Estate of Barbara M. Johnson Ambassador Brenda LaGrange Johnson and J. Howard Johnson Mr. Bruce Johnson Mr. C. G. Johnson Mrs. Charlene A. Johnson and Estate of Larry Johnson Mr. and Mrs. Darrel D. Johnson Mr. and Mrs. David J. Johnson Ms. Diana Johnson Mr. and Mrs. Ernest Johnson Mr. and Mrs. James A. Johnson Mr. Jared R. Johnson Mr. John E. Johnson Mr. and Mrs. Larry D. Johnson Ms. Leanne Johnson Mr. and Mrs. Louis Johnson Mr. and Mrs. Preston Johnson, Jr. Mr. and Mrs. Robert W. Johnson Mr. and Mrs. Scot W. Johnson Mr. and Ms. Sylvester P. Johnson IV Mr. and Mrs. Tom Johnson Dr. Virginia Johnson Mr. William F. Johnson Johnson & Family Foundation Employees of Johnson & Johnson Johnson & Johnson Johnson & Johnson Foundation Johnson & Johnson Services, Inc. The Johnson Family Foundation The Robert Wood Johnson Foundation The Tom and Edwina Johnson Family Foundation Mr. and Mrs. John Bishop Johnston Elva Johnston Foundation The Ralph A. Johnston Foundation, Inc. Jaylene and Richard Jolly Mrs. Virginia H. Jolly Mr. and Mrs. A. V. Jones, Jr. Mr. and Mrs. Bob Jones Mr. Clark Jones Mr. Edgar Bobby Jones Mr. Frank L. Jones Mr. J. Paul Jones Mr. Jack G. Jones Mr. and Mrs. Jeffrey Jones Mr. and Mrs. Jerry G. Jones, Sr. Mr. and Mrs. Jon Rex Jones Mrs. Patricia Pettway Jones Mr. and Mrs. Rex A. Jones Theodore and Arline Ann Jones Mr. and Mrs. Virgil Wayne Jones Mr. W. B. Jones, Jr. Jones Day Mr. and Mrs. James T. Jongebloed, Sr. Mrs. Edwin B. Jordan Mr. John W. Jordan II Mr. and Mrs. Lenoir M. Josey II Joshtom Millwork Joshua Engineering Group, Inc. Mrs. Eunice Jostes JPMorgan Chase Bank, N.A. JPMorgan Chase Foundation Mrs. Diane Judah-Mayberry Mr. and Mrs. Ardon B. Judd, Jr. Mrs. Susan D. Juden The Junior League of Houston, Inc. Dr. Kathy Jurell and Mr. Kim Jurell Mr. Jim Justen Mr. and Mrs. James F. Justiss, Jr. Justiss Oil Company, Inc. JWC Covenant, Inc. Sir Michael and Lady Kadoorie

Mr. and Mrs. Jeremiah R. Kafka Mrs. Terri Kahla Mr. and Mrs. W. Barry Kahn Mr. and Mrs. Bill Kalinec Mr. Parviz Kamangar Parviz Kamangar Charitable Foundation Mr. and Mrs. Jerry Kane Lily and Alan Kanter Mrs. Dorothy Kapelanski Joan and Marvin Kaplan Robert and Terri Kaplan Mr. William J. Kaplan Kaplan Inc. Kappa Alpha Psi Mr. and Mrs. Joe Kares Karl Storz Endoscopy-America, Inc. Karsten Interior Services, L.P. Mr. William M. Kasch Mr. and Mrs. Ron Kasik Mr. Bruce M. Kasper Mr. and Mrs. Mohammad Kassem Mr. and Mrs. Morris J. Kastner Mr. Alexander S. Katz Mr. Peter A. Katz The Rosalie Katz Family Foundation, Inc. Abraham J. and Phyllis Katz Foundation Mr. and Mrs. Jonathan A. Kay Kay R. McMillan Investments The Kayser Foundation Mr. and Mrs. Thomas L. Kazokas KBR, Inc. Mr. and Mrs. William Kenneth Keag Mr. and Mrs. James L. Keating Dr. and Mrs. Michael J. Keating W. M. Keck Foundation Craig Keeland Mrs. Donna Keeling Mr. and Mrs. Douglas H. Keeling Mr. and Mrs. James M. Keelor Dr. Ralph Keen Mr. and Mrs. Hilliard M. Keeney Mr. and Mrs. Henry Keeth The Honorable and Mrs. James L. Keffer Mrs. Carole P. Keiffer Estate of Mildred H. Keith Mr. and Mrs. Herbert D. Kelleher The Joan and Herb Kelleher Charitable Foundation Mr. and Mrs. Peter G. Keller Mr. and Mrs. Aubrey R. Kelley Mr. James J. Kelley, Jr. Mr. and Mrs. John F. Kelley Mr. and Mrs. Robert L. Kelley Mr. Russell T. Kelley Mr. and Mrs. Larry Kellner Dr. Robert R. Kellogg, Jr. Employees of Kellogg Brown and Root W. K. Kellogg Foundation Mr. Jeffery Kelly Mr. and Mrs. Richard J. Kelly Susie and Pat Kelly Mrs. Katherine B. Kelso Mr. Garth Kemp Mr. and Mrs. I. H. Kempner III Mrs. Mary A. Kendrick The John G. and Marie Stella Kenedy Memorial Foundation Mr. and Mrs. Bill Kennedy Mrs. Carolyn C. Kennedy Mr. and Mrs. James C. Kennedy Mr. and Mrs. Ronald E. Kennedy Ms. Rose Mary Kennedy Mr. W. Elton Kennedy Dr. and Mrs. Vernon E. Kenner Keown Charitable Foundation Kern Oil & Refining Co. Mr. Bryan W. Kerns Mr. James K. Kerr Dr. and Mrs. Matthew M. Kershisnik

M. D. Anderson Annual Report 2007-2008 Mr. and Mrs. Albert Kessler Mr. and Mrs. Paul D. Kestler Mr. and Mrs. George F. Kettle Key Allegro Real Estate I, Inc. Estate of Willet Keyser Ms. Christine Simoneaux Kibbe Mr. and Mrs. Don Kidd Kidney Cancer Association Mr. and Mrs. Craig S. Kiefer Mr. and Mrs. Bruce O. Kifer Mrs. Lora Jean Kilroy Kilts & Clubs Mr. and Mrs. John Z. Kimberlin, Jr. Kimberly-Clark Corporation Mr. and Mrs. Curtis C. Kimbrell Mr. and Mrs. Marvin P. Kimmel Mr. and Mrs. Robert A. Kimmel Mr. Sidney Kimmel Sidney Kimmel Foundation Ms. Anne Lamkin Kinder Nancy and Rich Kinder/Kinder Foundation Mr. and Mrs. Clinton H. King Estate of Dolores E. King Mr. Gary A. King Mr. and Mrs. Graham O. King Mr. and Mrs. John S. King Mr. and Mrs. John W. King Mrs. Kathleen R. King Mr. Michael P. King Mr. Thomas M. King, Jr. Mr. Michael Kinsey Mr. and Mrs. Jack L. Kirby Kirby Inland Marine, Inc. Mr. and Mrs. Hans J. Kirchner Mr. Carl D. Kirk Dr. and Mrs. I. Raymond Kirk III Mrs. Kim Kirkconnell Ms. Debra Kirkley and Mr. Larry V. Streepy, Jr. Mr. and Mrs. Cliff Kirkmyer Mr. and Mrs. Joachim R. Kirsten Kissick Family Foundation Dr. and Mrs. Henry A. Kissinger Mr. Benjamin F. Kitchen Kitchen Pride Mushroom Farms, Inc. Ms. Diane Klancher Klapprodt’s Kustom Pools and Spas Mrs. Alvin A. Klein Mr. David N. Klein Mr. and Mrs. Melvyn N. Klein Mr. and Mrs. Michael L. Klein The Klein Family Foundation, Inc. Alvin A. and Roberta T. Klein Trust Ms. Martha R. Kleymeyer Mr. and Mrs. William P. Kliewer Mrs. Edward J. Kloess Mrs. Guta Klug Klug Family Foundation KNA Partners Angela and Bob Knauss Mr. and Mrs. Don R. Knauss Ms. Carla A. Kneipp Mr. John S. Knight Mr. George W. Knorr, Jr. Ms. Mary Louise Knowlton Mr. and Mrs. Karl A. Knudson Mr. and Mrs. William H. Knull III Mr. and Mrs. Mark T. Kobelan Mr. and Mrs. Howard M. Kobrin Mr. David H. Koch Mr. and Mrs. Edward Kocurek Jeff and Gail Kodosky Mr. and Mrs. Kevin B. Koecher, Jr. Mrs. Pam Koenig Mr. and Mrs. Herbert V. Kohler, Jr. Kohler Company Dr. Harold Kohlmann Susan G. Komen for the Cure Mr. and Mrs. Michael Konrad Mr. and Mrs. Donald Kopka Mr. Anthony F. Kopp

Linda and Robert Korb Dr. and Mrs. John T. Korinek Dr. Barbara Kornblau and Dr. Donald J. Kornblau Mr. and Mrs. Allan B. Korsakov Saranne and Livingston Kosberg Amy and Mark Kovac Cindy and Greg Kozmetsky Tom Kraft Stephen J. Kramer, M.D. The Gladys and Lee A. Krause Jr. Fund of the Lutheran Community Foundation Mr. David A. Krebs, Jr. Mr. Michael J. Krenek Krescent Energy Company, LLC Mr. and Mrs. Sandy Kress Mr. Bruce Krier Dr. Margaret L. Kripke and Dr. Isaiah J. Fidler Mr. and Mrs. Ronald D. Krist Kristine Michael Apparel, Inc. Mr. Roger C. Krueger Mr. and Mrs. Richard M. Kruger Ms. Emily B. Kruglick Dr. Iris M. Krupp Mr. and Mrs. Edward F. Kruse Mr. and Mrs. Paul W. Kruse Ms. Marie E. Kuber Henry M. Kuerer, M.D., Ph.D., F.A.C.S. Kulp Foundation Mr. Larry L. Kunkel Gene and Mary Lou Kurtz Mr. Robert R. Kurz Mr. Michael Kutsch Mr. and Mrs. George F. Kutzschbach KW Cares Kyphon Inc. Dr. and Mrs. Demos T. Kyrazis L & F Distrubutors, Ltd. Mr. and Mrs. W. E. La Mothe Mr. and Mrs. R. Bruce LaBoon Mr. and Mrs. Bob Lacey Mrs. Juliette LaChapelle and Dr. Martin Runciman Mr. and Mrs. Todd E. Lachenmyer Mr. Kent Lacy Mr. and Mrs. Bert Ladd Ms. Jessica M. Ladd Ladies Auxiliary to the Veterans of Foreign Wars-Department of Texas Ladies Leukemia League, Inc. Mr. and Mrs. Akbar Ladjevardian Mr. and Mrs. Mohammad Ladjevardian Mr. Brian A. Laeger Mr. Albert Lai Mr. and Mrs. Steven E. Lambert Patricia A. LaMothe & William E. LaMothe Foundation Mrs. Gladiola Lampley Mr. and Mrs. Mason H. Lampton Lancer Resources, LP Land O’Lakes Purina Feed LLC Mr. and Mrs. John R. Landon Dr. Richard S. Landrum Mr. Eric S. Lane Ms. Marilyn Bonner Lane Mr. and Mrs. John J. Langdon Mr. and Mrs. Philip H. Lanham The Honorable and Mrs. Robert C. Lanier Lanier Operating Foundation Lapharcon LLC Mr. and Mrs. Jack Lapin The Susan and Jack Lapin Family Foundation Mr. Richard M. Larabee Laredo Petroleum Inc. Estate of Kay D. Laro The Larry Brand Memorial Golf Tournament Mr. and Mrs. Brent Larsen

Mr. and Mrs. Edgar M. Larsen Mr. and Mrs. Henry J. Lartigue, Jr. Mrs. Linda M. Last Mr. and Mrs. Ben Latham Ms. Margaret Latimer Mr. Trent B. Latshaw Mrs. Helen H. Laughery Ms. Erica Laughlin Mr. and Mrs. John F. Lauletta Mr. Angel R. Laurel Mr. and Mrs. Oscar M. Laurel, Jr. Laurel Minerals, Ltd. Mr. Karl Lauritzen Denny B. Law and Clorine N. Law Mr. and Mrs. Gavin A. Law Law Offices of Jones & Jones, Inc. Lawn Management Company Inc. Mr. and Mrs. C. Berdon Lawrence Estate of Michael G. Lawrence Mr. and Mrs. Charles A. Lay Miss Dorothy Lay Ms. Lucy T. Le Mr. and Mrs. Leon J. Leach Rita and Dick Leathers Dr. Milam E. Leavens Mr. Peter S. LeBlond Mr. and Mrs. Joe Leblow Mr. and Mrs. Rudi Lechner Lecturelinx, LLC Mrs. Joy G. Ledbetter Leddy Ventures Limited Mr. and Mrs. Donald Lee Mr. and Mrs. Eddie L. Lee Mr. and Mrs. Edward T. Lee Mrs. Gin-Ru Lee Dr. Linda D. Lee The Lee Firm, PC Sara Lee Foundation Lee Memorial Health System Foundation, Inc. Dr. Norman E. Leeds in honor of Ms. Bette G. Leeds LaSalle D. Leffall, Jr., M.D. Mr. and Mrs. William Lefkofsky Legal Media, Inc. Ms. Diane Legg Mr. William M. Legg Legge, Farrow, Kimmitt, McGrath & Brown, L.L.P. Lehman Brothers The Lehman Brothers Foundation Mr. and Mrs. Jay S. Leiber Bobby and Christopher Leidy Mr. and Mrs. Henry F. LeMieux Gary and Jan Lemmon Lenox Hill Hospital The Lents Foundation Ms. Ann Lents and Mr. J. David Heaney Mr. and Mrs. Craig R. Lentzsch Mr. and Mrs. Joseph L. Leonard Mrs. Marty V. Leonard George and Shirley Lerom Mr. and Mrs. Gary T. Leseman Mr. Philip Daren Lesley Mr. Lewis Arnold Lester Mr. and Mrs. W. Howard Lester The Leukemia & Lymphoma Society Leukemia Texas, Inc. Mr. and Mrs. J. Waymon Levell Mr. Daniel S. Leventhal Mrs. Sylvia Levin Mrs. Lee Levit Rochelle and Max Levit Milton and Lee Levit Family/Max and Rochelle Levit Family Mr. Irwin L. Levowitz Mr. Robert E. Levy The Meyer Levy Charitable Foundation Rachel Levy Goldberg Mara Elizabeth Levy Tobin Janel Levy Michael R. Levy

Mr. Chris W. Lewis Mr. Michael A. Lewis Mr. and Mrs. R. Dean Lewis Mr. and Mrs. Rodney R. Lewis Lewis Foundation The Kim and Rod Lewis Family Foundation For Hope & Charity Ms. Peggy H. Ley Mr. Richard A. Leyendecker Liberty County Teachers Federal Credit Union Mr. and Mrs. Jerome B. Libin Mrs. William C. Liedtke, Jr. Life Biosystems, Inc. Julie Lightfoot, Discovery Toys Captain Thomas N. Lightsey, Jr. Lime Rock Resources Leo and Bette Linbeck, Jr. Linder & Associates, Inc. George B. Lindler Foundation George B. & Irene Lindler Foundation Mr. and Mrs. Richard J. Lindley, Jr. Mr. and Mrs. Steven J. Lindley Mr. and Mrs. Robert Lindman Mr. and Mrs. John L. Lindquist Mr. Jonathan S. Linker Mr. and Mrs. Donald H. Linn Linn Energy, LLC Ms. Nancy A. Linton Lionstone Partners, Ltd. Mr. and Mrs. Charles C. Lipscomb Mr. and Mrs. Joseph Listengart Mr. and Mrs. Joel M. Litman Mr. and Mrs. Dan Little Mr. and Mrs. Jacques M. Littlefield Mr. and Mrs. Jason P. Littlejohn Mrs. Francis S. Livermore Mr. Ron Livingston Mr. Stephan Livingston Ms. Sandra Lloyd and Mr. Walter Douglass Smith Lloyds LMA North America, Inc. Mr. Bryan Joseph Lobo Mr. and Mrs. Richard A. Lobo Locke Lord Bissell & Liddell LLP Lockheed Martin Matching Gift Program for Colleges and Universities - The Scholarship Foundation Locus Technology, Inc. Mr. Norbert Lodygowski Mr. and Mrs. Lance T. Loeffler Nancy B. Loeffler The Honorable Tom Loeffler Mr. Michael D. Loehr Estate of Kathy A. Loera Mrs. Mary T. Loftis Mr. and Mrs. Ronald E. Lohec Mr. Christopher S. Lolley In Memory of Mr. Vince Lombardo Sr. Lone Star Beef Processors, L.P. Mr. and Mrs. David Long Mr. and Mrs. Robert L. Long Mr. Kenneth A. Longacre Gillson Longenbaugh Foundation The Longevity Foundation Mr. and Mrs. Harold Longhofer Israel Omar Longoria Memorial Fund for Esthesioneuroblastoma Research Mr. and Mrs. Harry J. Longwell/ Longwell Family Foundation The Norma & Harry Longwell Family Foundation Ms. Anne B. Loo and Mr. Brad Nyberg Mr. and Mrs. Gary O. Loo Mrs. Katherine H. Loo Mr. and Mrs. Donald E. Lookadoo Mrs. Carole Walter Looke Ms. Susan E. Loosen Mr. and Mrs. Howard S. Lorch Mr. Richard E. Lore, Sr.

Mrs. Sara P. Loshak Louis Dreyfus Highbridge Energy Louis Vuitton North America Mr. and Mrs. Gregory J. Lovasz Ms. Peggy Love Ms. Mary Ralph Lowe The Lowe Foundation Ms. Abbe Lowell Mr. and Mrs. Steve Loy, Jr. Mr. and Mrs. Lamar E. Loyd Mrs. Marilyn J. Lubetkin The Lubrizol Foundation Luca Luca Mr. and Mrs. Mark C. Lucas Mrs. Seymour Luckoff Mrs. Kathryn H. Luke Mr. and Mrs. Robert W. Luker Mrs. Pearl Lundburg Mr. Wallace L. Lundgren, Sr. Lung Cancer Research Foundation Mrs. Betty Lunsford Estate of Fred H. Lunsford, Sr. Mr. and Mrs. Ted W. Lusher Mr. and Mrs. Homer L. Luther, Jr. Mr. and Mrs. Jesse P. Luton, Jr. Mrs. Rosemary K. Lykos Estate of Rachel Lyman Lymphoma Research Foundation Dr. Mary Lynch and Dr. Patrick M. Lynch Mr. and Mrs. Timothy Lynch Lyondell Chemical Company M.C. Management & Development, Inc. Mr. and Mrs. Ian M. MacDonald Mr. and Mrs. C. Robert Mace Mr. and Mrs. Roy W. Mace Mach Family Fund Mach Industrial Group Mr. and Mrs. Robert L. Mack Mr. and Mrs. David O. MacKenzie Major and Mrs. Paul D. Mackenzie Mrs. B. John Mackin MacPapers Incorporated Advised Fund Mr. and Mrs. John P. Madden Mr. and Mrs. John W. Madden, Jr. Mr. and Mrs. Wales H. Madden, Jr. Mr. and Mrs. James E. Madget Ms. Beth Madison Madison Charitable Foundation, Inc. Madisonville State Bank Clayton and Andrew Maebius Ron Mafrige and Family Magnum Producing LP Mrs. Caroline C. Magoon Mr. Navid A. Mahmoodzadegan Robert W. Mahoney and Kathi Sibel Mr. and Mrs. Bob Mahr Mr. Harry M. Main Mr. and Mrs. S. Lewis Main Mainland Communities United Way Mrs. Josephine Majnik Mr. Edward F. Malanda Malaysian Palm Oil Board The Honorable and Mrs. Frederic V. Malek Malibu Floors Dr. and Mrs. Michael S. Maling Mr. James A. Mallak Dr. Meredith Mallory, Jr. Mr. Thomas W. Malone Malone Law Office Mr. Arnold I. Mangen Mangen Family Charitable Foundation Harry T. Mangurian, Jr. Mr. and Mrs. David D. Mann Mr. and Mrs. Bryant L. Manning Mr. Jed R. Manocherian Dr. Ellen F. Manzullo Mr. Burt Marans Marathon Oil Corporation 81

Partners in Making Cancer History® Marcella Intermediate School Estate of Betty B. Marcus The Marcus Foundation Mr. and Mrs. Joe A. Marek Zane and Rebekah Marek Ms. Jeanette E. Mares Estate of Viola H. Marger Mr. and Mrs. Rodney H. Margolis The Rodney H. and Judy E. Margolis Foundation Margolis, Phipps & Wright, P.C. Marin Community Foundation Mrs. Ellen Marino Mr. and Mrs. J. Stephen Marks Mr. Steve M. Marks The Marks Charitable Foundation Mr. and Mrs. Charles A. Marsh Mrs. Jo Marsh Wendy and Stanley Marsh 3 Marsh & McLennan Companies, Inc. Estate of Alma Lee Marshall Mrs. Diana E. Marshall Mrs. Marie M. Marshall Mr. Marion H. Marshall Mr. and Mrs. Frank D. Martell, Sr. Mr. Wes Marti Mr. J. Stephen Martin

Jack and Patsy Martin Estate of Josephine Williams Martin Mr. and Mrs. Simon I. Martin Mr. and Mrs. Joseph Martirano Mr. and Mrs. Benjamin L. Marx Masefield International, Inc. Masimo Americas, Inc. John B. and Doris Casey Mason Stuart and Flora Mason Mr. Tony Masraff Master Tubulars, Inc. Mr. and Mrs. Eric E. Masterson Jennifer Matsui and her Friends Ms. Ethel Matsuno Mr. Jack Matt, Jr. Mr. William C. Mattei Mr. and Mrs. Kade L. Matthews Lucinda and Bill Matthews Ms. Rebecca Matthews and Mr. James F. Wallack Mr. and Mrs. Steve Mattingly Mr. Wayne L. Matus The Florence Mauboules Charitable Trust Mrs. Patricia N. Maunder Mr. and Mrs. Michael W. Mauritz Mrs. Veda N. Mauzy

Mauzy & Associates, Inc. Mr. and Mrs. Page Maxson Mr. and Mrs. W. Keith Maxwell III Dr. and Mrs. David C. May Ms. Melinda J. May Susan S. May and Andy Owczarek Dr. Dan Maydan Mr. and Mrs. Ed Ross Mayers, Jr. Roy and Nancy Mayers Mr. and Mrs. Kenneth R. Mayfield Ms. Ofelia M. Mayo and Mr. Mike VanDusen Lowry and Peggy Mays Mays Family Foundation Mr. and Mrs. James A. McAllen Mr. Richard McAllister Mr. and Mrs. Ross McAlpine, Jr. Mr. Bob McAmis Mr. David L. McArdle Dr. and Mrs. Mark J. McArthur Mr. and Mrs. Robert H. McAuliffe, Sr. Mrs. Dolores L. McCall John H. McCall and Suzanne Kawaters McCann Healthcare Worldwide Japan Inc. Mr. and Mrs. Dennis W. McCarthy

The Honorable and Mrs. Austin McCloud Mr. and Mrs. B. Curtiss McClymond Mr. and Mrs. Hugh L. McColl, Jr. Linda and Howard McCollum Mr. Robert A. McCollum Red and Charline McCombs The Red and Charline McCombs Family Foundation Nancy and Walter McConnell Jim and Kathy McCool Mrs. Wanna McCorkell Mr. and Mrs. Donald McCoy McCoy Workplace Solutions Mr. Richard E. McCreary, Jr. Mrs. Lesley McCreath, Jr. Mr. and Mrs. Andrew D. McCullough, Jr. Mr. Thomas B. McDade Mr. Charles B. McDaniel Mr. Clifton M. McDaniels The David McDavid Family Mrs. Beverly T. McDonald Stephen M. and Sherry J. McEachern Mrs. Arthur L. McElmurry Mr. David W. McElroy Mr. and Mrs. Jay C. McElroy

Mr. M. Kevin McEvoy McFadin Foundation Mr. and Mrs. W. J. McFarland Mr. and Mrs. Patrick K. McGee Mr. and Mrs. William M. McGee Mr. and Mrs. Sutton McGehee Mr. and Mrs. Michael E. McGinnis Ms. Marcia B. McGlothlin Mr. Blaise L. McGoey John P. McGovern, M.D. Mr. Edward McGowan Ms. Robyn McGrath Mrs. Consuelo H. McHugh Mr. and Mrs. M. Joseph McHugh Mr. William A. McIntosh McIntosh Foundation, Inc. Mr. James B. McIntyre Mr. and Mrs. Glen F. McIver Mr. and Mrs. H. H. McJunkin, Jr. Mr. and Mrs. Howard P. McJunkin, Jr. Mrs. Bobbie N. McKamy Mr. and Mrs. Barksdale McKay Mr. and Mrs. Jim McKay Mr. and Mrs. Joseph J. McKernan Mrs. Lillian Herbelin McKibben Mr. and Mrs. Neal G. McKim

The Anderson Assembly* Since its inception in 1989, The Anderson Assembly has recognized those whose support and financial contributions have enabled M. D. Anderson’s continued growth and progress. Listed here are members who have given $1 million or more to support M. D. Anderson programs. Mr. and Mrs. Albert B. Alkek Amgen, Inc. Homer Ammann Trust M. D. Anderson Foundation AstraZeneca LP Mr. and Mrs. Perry R. Bass Estate of Gwin C. Blair Mr. Jack S. Blanton, Sr. Breast Cancer Research Foundation Bristol-Meyers Squibb Oncology Mrs. Eleine Brooks Mr. Kyle C. Brooks The Brown Foundation, Inc. David Bruton, Jr. Charitable Trust Burlington Resources Charles C. Butt Kathleen Cailloux Family Foundation Gordon and Mary Cain Foundation CaP CURE The Cockrell Foundation The Cullen Foundation The Cullen Trust for Health Care Mrs. Delmer W. Dallas The Sidney and Charline Dauphin Foundation Mr. William J. Dore’, Sr. John S. Dunn Research Foundation The Margaret and James A. Elkins, Jr. Foundation The Ellwood Foundation Enron Corporation Exxon Corporation ExxonMobil Foundation Farmer Family Foundation The Favrot Fund Carolyn Grant Fay Ray C. Fish Foundation

Louis and Gloria Flanzer Charitable Trust Mr. and Mrs. George E. Foreman Gillson Logenbaugh Foundation Mose A. Gimbel Golfers Against Cancer Mr. Harold V. Goodman Mr. and Mrs. William H. Goodwin, Jr. Estate of Dr. and Mrs. Ference Gyorkey Mr. and Mrs. Paul R. Haas The Hamill Foundation The Hawn Foundation Hoffmann-LaRoche Inc. Mike Hogg Fund The Hoglund Foundation Houston Endowment Inc. Roy M. and Phyllis Gough Huffington Interferon Foundation Introgen Therapeutics, Inc. Mr. and Mrs. Joseph D. Jamail, Jr. M. G. and Lillie A. Johnson Foundation, Inc. Mr. and Mrs. Michael Kadoorie W. M. Keck Foundation Killam Family Foundation Kimberly-Clark Foundation Kinder Foundation Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation Estate of Ellen F. Knisley Mr. and Mrs. David H. Koch Estate of Lillian C. Koehler Susan G. Komen Breast Cancer Foundation The State of Kuwait Mr. and Mrs. William Kyte Estate of Emma Lou Lancaster

Mrs. Theodore N. Law Mr. and Mrs. C. Berdon Lawrence Mr. and Mrs. Howard Lester Mr. and Mrs. Milton Levit and Family Mr. and Mrs. Max Levit and Family Mr. and Mrs. Thomas C. Liebman Mr. and Mrs. John T. Lockton, III Mr. and Mrs. Ben F. Love G. Harold and Leila Y. Mathers Charitable Foundation M. D. Matthews Foundation John P. McGovern Foundation Estate of Anne W. Midgley McGraw J. Ralph and Lillian H. Meadows Mr. and Mrs. LeRoy Melcher Mr. and Mrs. George P. Mitchell Estate of A. Clifton Mock W. A. “Tex” and Deborah Moncrief, Jr. Estate of Mary E. Montrose Estate of Louise J. Moran Estate of Frances Morse Ralph E. and Virginia Mullin Estate of Wanda L. Murry The Robert R. and Kay M. Onstead Foundation Elsa U. Pardee Foundation Ray Park and Family Pennzoil-Quaker State Company (Pennzoil Company) Mr. Boone Pickens Bernard and Audre Rapoport Sid W. Richardson Foundation Corbin J. Robertson and Wilhelmina C. Robertson Smith Ben, Julie and Regina Rogers Estate of David Rosenstone Rotary Club of Houston Foundation Inc.

Samsung Electronics America, Inc. SBC Foundation Schering-Plough Corporation Estate of Gene Schulze Estate of Dr. Samuel Schwartzberg Shell Oil Company Foundation Cecil P. and Anna C. Simpson Clara B. and W. Aubrey Smith Charitable Foundation R. E. “Bob” and Vivian L. Smith Mr. and Mrs. George Strawbridge, Jr. Dr. and Mrs. John C. W. Taylor T.L.L. Temple Foundation Tenneco Inc. Texas Federation of Business and Professional Women’s Clubs, Inc. William G. and Dorothy K. Theisinger Timken Foundation of Canton Mr. and Mrs. Morton L. Topfer Estate of Harold L. Tull Herbert H. and Katharine Moore Unsworth Vale-Asche Foundation Mr. and Mrs. J. Virgil Waggoner Walton Family Foundation, Inc. The Robert A. Welch Foundation Neva and Wesley West Foundation Harry Carothers and Olga Keith Wiess The Wortham Foundation, Inc. Mr. and Mrs. Oscar S. Wyatt, Jr. *This historical listing reflects the original names of individuals, foundations and corporations as they were brought into The Anderson Assembly.

M. D. Anderson Annual Report 2007-2008 Ms. Mary E. McKinney Mr. Michael D. McKinnon Mr. and Mrs. Don A. McKnight The Reverend and Mrs. Alexander S. McLachlan Mr. Darrell G. McLain Mr. and Mrs. Drayton McLane, Jr. Mr. and Mrs. Thomas F. McLarty, III Dr. Darlene W. McLaughlin and Mr. James McLaughlin, Jr. Mr. and Mrs. W. David McLaughlin McLaughlin Ranch Mrs. Bert A. McLean Mr. and Mrs. Bruce W. McLean Mr. and Mrs. Leo McLean Mr. and Mrs. Gordon McMillan Mrs. Kay R. McMillan Mr. and Mrs. Robert I. McMillan Bruce McMillan, Jr. Foundation Mr. and Mrs. Douglas McMillen Mr. Robert R. McMillian Don and Colletta McMillian Foundation Dr. Jeanie B. McMillin-Vanwinkle Mr. and Mrs. Robert C. McNair The Robert and Janice McNair Foundation Ms. Leslie E. McNeill Mrs. Vickie McRay Ms. Debra G. McReynolds Mr. and Mrs. Charles D. McVean Mr. Steven L. McVicker Mr. and Mrs. William A. Meadlock The Meadlock Foundation Mr. and Mrs. Henry E. Meadows Mr. Lynn W. Meadows George H. and Martha G. Meason Medical Funding Corporation Medical Technology Management Institute, Inc. Mr. James G. Medill Mr. and Mrs. Joe E. Medina Mrs. Leslie Kim Medlin and Mr. Thomas V. Costantino Medtronic, Inc. Mr. and Mrs. Edward M. Medvene Ms. Linda Meek Mrs. Sue E. Meek The Meek Foundation Ms. Amanda S. Meers and Mr. James K. Weber Mr. Terry C. Mehaffie Mr. and Mrs. John Mehan Mehta Family Foundation Ms. Elke B. Meier and Dr. William B. Gail Melanoma Research Alliance Melanoma Research Foundation Mr. Pablo Melchor Memorial Hermann Hospital System Memorial Regional Hospital Pharmacy Dr. and Mrs. John Mendelsohn Dr. and Mrs. Gary Mennie Mr. and Mrs. Michael J. Menzer Mr. and Mrs. Timothy Mercer Merck & Co., Inc. Meredith Mallory Jr. Investments Mrs. Ida K. Merfish Mr. Kenneth L. Mermis Merrill Lynch & Co., Inc. Merrill Lynch & Company Foundation Mr. and Mrs. Shane Merz Colonel and Mrs. Robert A. Mesick Ms. Kathleen A. Messina and Mr. Gary W. Goodwin Metalforms, Inc. Steve and Roslyn Metchis Methods, Inc. MetLife Foundation Estate of O. Frances Metz Mr. and Mrs. Kirby T. Meyer Ms. Nancy Ellen Meyer

Barbara and Randall Meyer Mr. and Mrs. Ronald Meyer MGI PHARMA, INC. Mr. and Mrs. Kenneth Michaels Mr. and Mrs. Mark D. Michaud Mr. and Mrs. George Michulka Micro Rentals, LLC Microsoft Corporation Microsoft Giving Campaign Mr. John G. Middleton Mr. Richard H. Middleton Midway Oilfield Constructors, Inc. The Mike Doiron Legends of Friendswood Golf Tournament Mikimoto (America) Co., Ltd. Millennium Pharmaceuticals, Inc. Millepede Foundation Ms. Barbara A. Miller Beverly and Marvin Miller Mr. and Mrs. C. Donald Miller, Jr. C. John and Reva Miller Mr. Cecil Miller Mr. and Mrs. David L. Miller Ms. Doris E. Miller and Mr. Donald R. Fitzgibbons Mr. and Mrs. Greg A. Miller Jan and Steve Miller Ms. Lena Miller Mary Catherine Miller Ms. Polly G. Miller Mr. Richard L. Miller Mr. and Mrs. Stephen Miller Mr. and Mrs. Steven L. Miller Mr. Theodore N. Miller Mr. and Mrs. Vance C. Miller, Sr. Gerald and Carole Miller Family Foundation The Miller Family Foundation Steven and Sheila Miller Foundation The Millers Apartment Mr. and Mrs. Edward L. Milligan Millipore Bioscience Division Mr. F. H. Mills, Jr. Mr. Gary G. Mills Mr. and Mrs. James R. Mills Dr. and Mrs. Keith R. Mills Mr. and Mrs. Robert B. Milsten The Minneapolis Foundation Minton, Burton, Foster & Collins Mrs. Dorothy Louise Miracle Mirror Industries Mrs. Mary A. Mischer Ms. Paula Mischer The Walter M. Mischer and Mary A. Mischer Foundation The Mississippi Charitable Foundation Mr. and Mrs. George P. Mitchell Mr. and Mrs. John R. Mitchell Mr. S. L. Mitchell The Cynthia and George Mitchell Foundation Mr. and Mrs. Richard W. Mithoff, Jr. The Mithoff Family Foundation Dr. Elizabeth A. Mittendorf Mr. Glen J. Mizenko Mrs. Eva M. Mizrahi MMR Enterprises, Inc. Mobil Foundation, Inc. Mr. and Mrs. Stephen L. Mobley Modestus Bauer Foundation Mr. and Mrs. James R. Moffett Mr. Mike Mogonye Mr. Brian A. Mohr Dr. and Mrs. Radhe Mohan Mr. and Mrs. Randolph M. Moity, Sr. Mr. and Mrs. Richard H. Molke, Jr. Mr. and Mrs. John C. Molloy Mr. and Mrs. Alexander B. Molten Jim and Elaine Monaghan Monaghan Medical Corporation Mr. and Mrs. Kenneth Monahan Mr. and Mrs. Charles B. Moncrief

Ms. Gloria Moncrief Mr. and Mrs. Mark K. Monroe Dr. Eleanor D. Montague Ms. Margaret Montaigne Mr. and Mrs. William A. Monteleone, Jr. Mr. and Mrs. Terry R. Montesi Mr. and Mrs. Ben C. Montgomery Mr. Miles C. Montgomery Mr. and Mrs. Ray Montgomery Mr. George W. Moody Mr. A. T. Moore Mr. and Mrs. Douglas D. Moore Ms. Elizabeth Moore Jess and Beth Sanders Moore Randy and Kaycie Moore Mrs. Dorothy Mooring Mr. and Mrs. Lewis J. Moorman III Mr. and Mrs. Dan J. Moran, Jr. Mr. and Mrs. John Moran Estate of Louise J. Moran Mr. and Mrs. Sidney Moran Mr. Thomas J. Moran Mrs. Alma W. Moreton Mr. Arthur J. Moretti Mr. and Mrs. Atho R. Morgan Bill and Sara Morgan Morgan Stanley Corporation Mr. and Mrs. Dud Morris Mr. and Mrs. Thomas C. Morris III Clifton and Sheridan Morris Fund Mr. Robert R. Morrison, Jr. Mrs. Sue Morrison Morrison Foundation Mr. and Mrs. Paul F. Morton The Honorable and Mrs. Robert A. Mosbacher, Sr. Mosbacher Foundation, Inc. Mr. Alfred H. Moses Mr. and Mrs. Roland I. Mosher Paula and Jon Mosle Mr. Wiley L. Mossy The Jane P. and Wiley L. Mossy Jr. Foundation Motec, Ltd. Ms. Kimberly Mount Clifton F. Mountain Foundation Mr. and Mrs. Jerry H. Mouser MTI MTI Logistics, Inc. Mr. Harvey H. Mueller, II Mr. and Mrs. Robert C. Mueller Mr. and Mrs. Thomas J. Mulkey Mr. and Mrs. Timothy T. Mullen Muller Honda Mr. and Mrs. Michael Mullins Mr. and Mrs. Joe C. Mullis Miriam and Jim Mulva Mr. and Mrs. Donald D. Muncy Munday Ford Mr. and Mrs. George W. Murfee Murphy Oil Corporation Mr. and Mrs. Austin S. Murr Mr. and Mrs. Robert D. Murrah Mr. John A. Murray, Jr. Mr. and Mrs. Michael P. Murray Ms. Sally Murray Muscular Dystrophy Association Musculoskeletal Transplant Foundation Mr. and Mrs. John R. Muse The Muse Educational Foundation Ms. Sara Musselman Mr. Elmer T. Musshorn James and Pamela Mustard Mr. and Mrs. David C. Myers Mr. Edward J. Myers Emily Erisman Myers Mrs. Maxine Myers Arthur B. & Marion V. Myers Trust Fund Myriad Genetics, Inc. Nabors Corporate Services, Inc.

Dr. Vijaya Nair Mr. David Nakamura, Sr. Mrs. Cheryl L. Napier Mr. and Mrs. Albert Narath Mr. and Mrs. Peter Nardo Mr. Jacques Nasser Claire and Jack Nath Charitable Foundation Mr. and Mrs. Jeff Nathanson National Ataxia Foundation National Brain Tumor Foundation National Breast Cancer Foundation, Inc. The National Christian Foundation National Foundation for Cancer Research Employees of National Instruments National Philanthropic Trust National Postdoctoral Association National Terrazzo, Tile & Marble, Inc. Mr. William V. L. Nations Ms. Mary Ida Naylor Ladan Nazari NBHA Texas District 34 NCME Holding Corporation Mr. and Mrs. C. R. Neal Dr. and Mrs. Warren F. Neely Mr. and Mrs. James P. Neeves Mr. and Mrs. Dan Neff Mr. and Mrs. Dru A. Neikirk Mr. Denis M. Neill Mrs. Laura B. Neill The Neiman Marcus Group, Inc. Nelsen Partners, Inc. Mrs. Deane A. Nelson Mr. and Mrs. Hunter Nelson Mr. and Mrs. John C. Nelson Ms. Marsha Nelson Mr. William C. Nelson, Jr. Dr. and Mrs. William J. Nelson Nelson Family Foundation Mr. and Mrs. Thomas B. Nenninger Ms. Sheila A. Nero Dr. Tom E. Nesbitt, Sr. John Nestor and Lacinda Riley The Neubauer Family Foundation Mr. Thomas Neuenfeldt Mr. and Mrs. Joseph R. Neuhaus, Jr. Neustadt Charitable Foundation New Electric, Inc. Mrs. Mary E. Newberry Mr. and Mrs. Randy Newcomer, Jr. Mr. and Mrs. David Newell Newfield Exploration Company Dr. and Mrs. Wayne D. Newhauser Mrs. Mary Ann Jameson Newman Mr. Keith O. Newton NexBank Nexen Inc. Nexen Petroleum U.S.A., Inc. Ms. Amy T. Ng Mrs. Mayawati Ngadiman NGP Capital Resources Company NGP Energy Capital Management, L.L.C. Mr. and Mrs. Eric Niccum Mr. and Mrs. Jason W. Nicholls and Family Mrs. Helen E. Nichols Mr. and Mrs. W. Robert Nichols III Ms. Elsa L. Nicholson Mr. James F. Nick III Ms. Lois E. Nickerson Mr. and Mrs. Jack W. Nicklaus Nino Corporate Lodging Inc. Mr. and Mrs. David A. Nisbet Estate of Lawrence E. Nix Nix Patterson & Roach, LLP Mr. and Mrs. Dennis E. Nixon Mr. and Mrs. William M. Noble, Sr. Mr. and Mrs. James W. Nobles, Jr. Mr. and Mrs. Edmund O. Noel Mr. and Mrs. James L. Noel III

Mrs. John P. Noel, Jr. Mr. and Mrs. William D. Noel Mr. and Mrs. Michael K. Noggle Mr. and Mrs. John A. Nolan Mr. Michael P. Nolan Mr. and Mrs. William J. Nolan, Sr. Nolan Bros. of Texas, Inc. Mr. and Mrs. Richard Noppe Mr. and Mrs. David W. Norburg Mr. and Mrs. Kenneth Norman Dellora A. and Lester J. Norris Foundation North Dallas Business and Professional Women Northern Trust Company Mr. and Mrs. H. M. Northington, Jr. Northrop Grumman Corporation Northstar Offshore Energy Partners, LLC Northville Product Services, LP Northwest Florida Praetorians, LEMC The Noto Family Foundation Notsew Orm Sands Foundation Novartis (Taiwan) Co. Ltd. Novartis (Thailand) Limited Novartis Oncology Novartis US Foundation Novo Nordisk Pharmaceuticals Inc. Mr. and Mrs. Wade T. Nowlin, Jr. Mr. and Mrs. Thomas B. Nusz Nycomed GmbH O. D. Rentals David and Joy Oates Mr. and Mrs. W. W. Oatman ObjectWin Foundation Mr. Raymond V. O’Brien, Jr. Dr. Susan O’Brien Obstetrical and Gynecological Associates, P.A. Occidental Oil & Gas Corporation Occidental Petroleum Corporation Mr. and Mrs. Dennis J. O’Connor Mr. and Mrs. Thomas M. O’Connor Mr. and Mrs. Thomas A. Oddo Ms. Zillah Oden Sydnor and Olga Oden Foundation Odin Marine Mr. Charles H. Odom Mrs. Rita Odom Odyssey Healthcare of Conroe Mr. and Mrs. John Oettinger Office Pavilion Houston, LTD. The OFIS Mr. and Mrs. Thomas E. Ogburn and Family Mr. and Mrs. Bradley W. O’Halla Beverly and Will O’Hara Mr. Jim Ohlms Mrs. Frances W. O’Hornett Ms. Leslie A. Ohr Mrs. Mary Ann Ohr Mrs. Anna H. O’Kelley Mrs. Judith R. Okun The Okun Family Foundation, Inc. Mrs. Ann M. Olesky Mrs. Paige E. Olive Bob and Karin Oliver Mr. and Mrs. David E. Oliver Dr. Judy L. Oliver and Dr. David W. Bash Rodney and Mary Ann Olivier Olshan Foundation Repair Mr. and Mrs. Rudolph K. Olson Olympus America Inc. Mr. and Mrs. Alan E. O’Martin Bradley O’Martin Melanoma Foundation Oncor Electric Delivery Mr. Ray L. & Mrs. Ellen Rebecca O’Neal Mr. and Mrs. Frank A. O’Neil Mr. John G. O’Neil Mr. and Mrs. Brian E. O’Neill 83

Partners in Making Cancer History® Mr. and Mrs. Harvey E. O’Neill Mr. and Mrs. James J. O’Neill Ms. Peggy L. O’Neill William J. and Dorothy K. O’Neill Foundation O’Neill Foundation Mrs. Kay M. Onstead The Robert R. and Kay M. Onstead Foundation Onyx Pharmaceuticals, Inc. Mr. and Mrs. Lawrence J. Opalka Mrs. Mildred M. Oppenheimer Oppenheimer Funds Legacy Program John M. O’Quinn Foundation Oral Cancer Foundation Estate of Gerard S. Orce Mr. Morris A. Orden Mr. and Mrs. Jerry W. O’Rear Mrs. Franca G. Oreffice Mr. and Mrs. Paul F. Oreffice The Oreffice Foundation Mr. David A. Orlando Ortho-McNeil Pharmaceutical, Inc. Orthopaedic Associates, L.L.P. in honor of John A. Murray, M.D. Dr. Robert B. Osborn Mr. and Mrs. Richard L. O’Shields The Oshman Foundation OSI Pharmaceuticals, Inc. Mr. and Mrs. Guy J. Ossello Mr. Axel R. Ostlund Otsuka America Pharmaceutical, Inc. Mr. and Mrs. Lee Roy Ott, Jr. Mrs. Jeanne Oudenhoven Ms. Anne Dale Owen Mr. and Mrs. David R. Owen Ms. Dian Graves Owen Mrs. Jane Blaffer Owen Mr. and Mrs. Kenneth A. Owen Mr. and Mrs. Travis A. Owen Dian Graves Owen Foundation Mr. James Richard Owens Mr. and Mrs. Alvin M. Owsley, Jr. Alvin and Lucy Owsley Foundation Mr. Lamar E. Ozley, Jr. The P and C Carroll Foundation Mr. and Mrs. Robert F. Pacquer Mr. and Mrs. Carter F. Page Mr. and Mrs. Robert R. Page Palm Management Corporation Mr. and Mrs. C. Robert Palmer Mr. and Mrs. David D. Palmer Mr. and Mrs. Gary Palmer Mr. Oscar M. Palmer, Jr. Palmer Foundation Mr. and Mrs. Bobby G. Pangle Mr. Joseph J. Pappas Pappas Restaurants, Inc. Elsa U. Pardee Foundation Mr. and Mrs. Henry Paris Mr. Leroy H. Paris II Mr. and Mrs. John L. Parish, Jr. Mr. and Mrs. Raymond P. Park The Park Foundation Mr. L. Parkans Mr. and Mrs. David Parker Dr. and Mrs. David L. Parker Mrs. Eugene J. Parker Mr. Jefferson Parker Mr. and Mrs. Jerre L. Parker Ms. Mary E. Parker Mr. and Mrs. Richard H. Parker Mrs. Robert A. Parker Mr. and Mrs. Scott L. Parker Robert A. Parker Foundation Mr. and Mrs. Stan Parmlee Mr. Jaime Parra Mr. Roger K. Parsons Mr. and Mrs. Charles A. Partain Mr. and Mrs. Tom Partlow Partners for a Cure Foundation Partners Healthcare System 84

Mr. Norman L. Pasas Mr. and Mrs. Lawrence R. Paschich Mr. George W. Pasha III Mr. Carl E. Patchin, Jr. Connie and Samuel Pate Mrs. Rose B. Patek Mr. and Mrs. Bharat R. Patel Dr. Daksha M. Patel Mr. and Mrs. Malcolm Paterson Dr. Sen Pathak Estate of Emae Miller Patin Mr. and Mrs. Gary J. Patin Ms. Sean J. Patrick Mr. and Mrs. Walter L. Patrick Patriot Bank Mr. C. Cary Patterson Mr. and Mrs. Gary R. Patterson John and Nora Patterson Mr. Robert W. Patterson Dr. Tad L. Patton Mr. Suhas P. Patwardhan Dr. and Mrs. James A. Paulson Mr. John E. Pawlik Ms. Debra Paxton Mrs. Ann L. Payne Mr. Garry Payne Mr. and Mrs. Leon M. Payne, Jr. Mr. Merrick D. Payne Payne Foundation PCD II Limited Mr. and Mrs. Arthur W. Peabody, Jr. Pearson Watson & Company LLC Pebble Technology, Inc. Pediatric Brain Tumor Foundation of the United States Mr. and Mrs. Daniel A. Pedrotti Mr. Bill Pegel The Pembroke Hill School Pemco Equipment Inc. Mr. David R. Pena Mr. and Mrs. Pablo G. Pena Richard and Kaye Pendleton Mr. and Mrs. Ken Pendray Mr. Gene Pennebaker Ms. Lisa Kelso Pennington Mr. Paul E. Pennington Pamela J. and James D. Penny Greg and Patty Penske John and Cheri Peper PepsiCo Foundation Per Group, L.P. Peregrine Capital Management, Inc. Peregrine Pharmaceuticals, Inc. Performance Diesel Inc. Mr. and Mrs. Richard D. Perkins The Dick and Judy Perkins Charitable Foundation Mr. and Mrs. H. Ross Perot, Sr. The Perot Foundation Dr. and Mrs. Dennis M. Perrotta Mr. and Mrs. Mills C. Perry Mr. and Mrs. Steven Pesner Mr. and Mrs. Charles P. Peterman Roger and Bernadette Peters Ms. Virginia L. Peters Ms. Margaret L. Petersen Mr. and Mrs. Donald N. Peterson Jeffrey and Candace Peterson Mr. Jim L. Peterson Petroleum Development Corporation Ms. June Pettus Mrs. Janet M. Pfeiffer Pfeiffer Family Foundation Pfizer Foundation, Inc. Pfizer, Inc. Ms. Marjorie L. Pflaum Mr. and Mrs. Jim Phalan Mr. and Mrs. Robert E. Phaneuf Pharmion Corporation Mr. and Mrs. Dionne S. Phelps Phi Beta Psi Sorority

Mr. and Mrs. Jack Phillips Ms. Jennie L. Phillips Mr. and Mrs. Mark Phillips Mr. Paul J. Phillips The Waite and Genevieve Phillips Foundation Mr. and Mrs. Eric J. Phinney PhRMA Mr. and Mrs. Ugo Piccagli Mr. Robert S. Pickelner Mr. and Mrs. Jim B. Pickens Mrs. Nelda Cain Pickens Mr. T. Boone Pickens Pierce, Fenner & Smith Inc. Mr. and Mrs. Fredrich J. Piette, Sr. Ed and H. Pillsbury Foundation Harriet Pillsbury Foundation Pinnacle Polymers Pioneer Natural Resources USA, Inc. Mr. and Mrs. Guy Pipitone Mr. and Mrs. Richard K. Pipkin Mrs. Charlotte Pippin Mr. Keith Pistocco Pitch and Putt For A Cure Mr. and Mrs. Bob Pitcock Dr. Carl Plager Plains Exploration and Production Company Mrs. Madeline C. Plansky Plantation Petroleum Holdings IV, LLC Mr. and Mrs. Todd Platt PlazaCorp Realty Advisors, Inc. Mr. and Mrs. W. Craig Plumhoff Pluspetrol S. A. Mr. and Mrs. Robert D. Poe Daniel and Robin Polasek and the Caring Kids of Buist Academy Mr. David G. Polis Mr. and Mrs. Joe E. Polk Mr. Philip K. Polkinghorn Pollard Foundation Inc. Mr. and Mrs. Jose Polo Polsinelli Shalton Flanigan Suelthaus PC Mrs. Lewis H. Pool Mr. and Mrs. Phillip B. Pool, Jr. and Family Lewis H. Pool Foundation Mr. and Mrs. William L. Poole III Poongsan America Corporation Mr. and Mrs. Bobby F. Pope Mr. Brett Pope Mr. James E. Popp Porter, Wright, Morris & Arthur LLP Mr. and Mrs. Don E. Posey Post Oak Energy Capital, LP Post Oak Motor Cars, LTD. Mrs. Marjorie M. Postma Mr. Bryan K. Poulos Mr. Greg Poulos Mr. and Mrs. Michael J. Poulos Miss Judith L. Powell Mr. Mark Powell Mr. and Mrs. Thomas L. Powell, Jr. Mr. and Mrs. Martin J. Power John and Jane Powers Foundation PR Sunglasses Mr. and Mrs. Richard E. Prasek Ms. Carmen C. Pratt Mrs. Susan S. Pratt Praxair Inc. Mr. and Mrs. G. Heyward Preacher, Jr. Precision Management & Construction, Inc. Precision Therapeutics, Inc. Premier Pipe, LLC Premium Drilling, Inc. Ms. Eileen Prendergast and Family Mrs. Sheila Prenowitz Presidio Title Mr. and Mrs. Richard L. Preston Prevent Cancer Foundation

Mr. and Mrs. Michael Prevor The Roslyn and Michael Prevor Charitable Foundation, Inc. Ms. Gina Price and Mr. Michael Kirschbaum Mr. and Mrs. Harvey S. Price Jerome M. Price PricewaterhouseCoopers LLP Pride International, Inc. Primary Natural Resources, Inc. Primrose School of Bedford Primrose School of Bent Trail Primrose School of Breckinridge Park Primrose School of Coppell Primrose School of Eldorado Primrose School of Stone Brooke Mr. and Mrs. John D. Prince Mrs. J. Phillip Pringle Mr. Kenneth O. Privat Producers Service Corporation Progeny Software, LLC Prosperity Bank Prostate Cancer Foundation Protection Engineering Consultants Protege Energy LLC Providence Energy Group Prudential Foundation William H. Prusoff Foundation Mr. Jessie D. Puckett, Jr. Mr. Gerry J. Pugil Mr. and Mrs. Cory M. Pullen Mr. Barry Pulliam Pulliam Pools Tillman R. Pullig Mr. and Mrs. Robert E. Pullin Mr. Matthew A. Purdy Mrs. Fredna E. Purkey Ms. Tracy L. Pursell Mr. and Mrs. Michael C. Puzio Mr. and Mrs. Joe E. Pybus, Jr. Mr. and Mrs. Jerry H. Pyle Ms. Patti Pyle Qualcomm Quality Electric Steel Castings, L.P. Mr. Eliot O. Qualy Quantum Gas & Power Services, Ltd. Quantum Resources Management, LLC Quest Medical, Inc. Questar Corporation Quicksilver Resources, Inc. Mr. and Mrs. Parker S. Quillen Quilt4Cancer, Inc. Mr. and Mrs. Larry W. Quimby R.D. Crumley & Sons, Inc. Leticia Casalduc Rabel and Juan Luis Casalduc Torruella Roger Allan Raby Mr. and Mrs. Ian C. Radomski Mr. and Mrs. Duane C. Radtke Mr. Adam D. Rafkin Mr. and Mrs. James Ragan The Ragsdale Foundation Railside Golf Club, Inc. Mr. Gene Rainbolt Mr. and Mrs. W. K. Rainbolt, Jr. Sen. Omer L. Rains RAM Energy Resources, Inc. The Honorable and Mrs. Tom B. Ramey, Jr. Ms. Therese S. Ramirez and Mr. George C. Billings Ramnas Bruk AB Mr. and Mrs. Ernest Ramos Ms. Kim E. Ramsey Mr. Ray Ramsey Mrs. Eliza Lovett Randall Mr. and Mrs. Jack P. Randall Roberta K. Randall Charitable Foundation Jack & Beverly Randall Foundation, Inc. Mr. and Mrs. Donald G. Randon

Ranger Die, Inc. Mr. Salvatore A. Ranieri Mr. and Mrs. B. M. Rankin, Jr. Ranparr, Inc. Ms. Renee M. Ransom Prashant Rao Sheryl and Ernie Rapp Estate of William J. Rapson Mr. and Mrs. Albert D. Rasberry Rasi Laboratories, Inc. Mr. Terry W. Rathert R. Byron and Bobbie Ratliff Mr. and Mrs. Lyle J. Ratner Mr. and Mrs. Keith O. Rattie Mr. and Mrs. Daniel C. Ratto Mr. and Mrs. Leonard Rauch Mr. and Mrs. Bharat Raval Mr. Stanley T. Rawley Stanley and Joyce Rawley Foundation L. P. Rawson Mr. and Mrs. Donald Ray Ms. Lynne Ray Mrs. Phyllis Ray Ms. Bess L. Rayford Bessie L. Rayford Foundation Mr. and Mrs. Martin S. Raymond Raytheon Matching Gifts for Education Program Mr. and Mrs. Brad Razook Dr. and Mrs. W. T. Read Mr. and Mrs. John C. Reap Ms. Brenda E. Reardon REcentis Intermediaries, LLC Mr. and Mrs. Thomas R. Reckling III Red Fork Mud Inc. Redwine Foundation Ms. Christy Reed Mr. and Mrs. Joe G. Reed Ms. Robin Reed Mr. and Mrs. Roman F. Reed The Reed Foundation Mr. and Mrs. H. Douglas Reese III Mr. Albert Regalis Ms. Alison T. Reid Mr. and Mrs. Andrew J. Reid Mr. and Mrs. Billy Reid Mr. Brent H. Reid Mrs. James H. Reid, Jr. Mr. and Mrs. Paul and Donna Reinbolt Mrs. Cindy Reinhardt Mr. and Mrs. John H. Reininga, Jr. Mr. Owen A. Reischman Mr. and Mrs. Rick Reitz The Reliable Specialty Company Miriam and Tim Relyea Renaissance Alaska, LLC Renfro Foods, Inc. Estate of Evelyn Marie Reno Renven, LLC The Reny Company Ms. Francy Renz Mrs. Dee A. Replogle Research Analysis & Maintenance, Inc. Estate of B. J. Resoft Ressler/Gertz Family Foundation Retail Concepts Retina Research Foundation Mr. and Mrs. Tomas Revesz Rexanna’s Foundation for Fighting Lung Cancer Mr. and Mrs. Charles T. Reynolds Mr. and Mrs. Fred N. Reynolds Mr. James H. Reynolds Mr. and Mrs. K. Earl Reynolds Mr. and Mrs. Lawrence E. Reynolds Ms. Lois C. Reynolds Mr. and Mrs. Robert D. Reynolds Catherine B. Reynolds Foundation RGK Foundation Rice Epicurean Markets Mr. and Mrs. Hershel M. Rich

M. D. Anderson Annual Report 2007-2008 Mr. and Mrs. Martin D. Rich Mr. and Mrs. Norman I. Rich Martin D. & Barbara H. Rich Family Charitable Foundation The Marc Rich Foundation Mr. and Mrs. Charles A. Richards Scott Richards North Star Charitable Foundation Mr. and Mrs. Frank H. Richardson Mr. and Mrs. Gaylon Richardson Mr. and Mrs. Jessie G. Richardson Mr. and Mrs. Robert B. Richardson Mrs. Sheila Richardson Sid W. Richardson Foundation Mr. and Mrs. Fred D. Richman Mr. Eugene P. Richter Liz and Al Richter Mr. Thomas G. Ricks Mr. and Mrs. John J. Riedmueller Mr. and Mrs. Aaron C. Riehl Dr. and Mrs. Leonard M. Riggs, Jr. Mr. and Mrs. Donald A. Rikard Mr. and Mrs. H. John Riley, Jr. Ms. Michele Riley Mr. and Mrs. Russ Rinn Mr. and Mrs. Patrick J. Riordan Mr. John Rippel Fannie E. Rippel Foundation Mr. James H. Rippy Ms. Jane F. Ritter Ms. Penny Helms Rivenbark Marsha Rivkin Center for Ovarian Cancer Research Mr. Marc E. Robb Mr. and Mrs. Alan B. Roberts Mr. and Mrs. Braxton L. Roberts, Jr. Mr. David E. Roberts, Jr. Mr. Richard H. Roberts

Mr. Rodney C. Roberts Ms. Sheryl L. Roberts Carol and Jack Robertson Mr. and Mrs. Charles L. Robertson, Jr. Dr. and Mrs. Daryl W. Robertson Ms. Ellen P. Robertson Mr. and Mrs. Jack Y. Robertson Mr. and Mrs. James S. Robertson Ms. Wynnell Robertson Mr. and Mrs. Frank Robin Mr. Craig Robinson Mrs. Edgar A. Robinson J. Mack Robinson Ruth Robinson and Family Mr. Paul M. Robshaw Roche Roche Diagnostics Mr. and Mrs. Rudy Rochelle Rock “N” Roll Coal Co. Mrs. Carolyn J. Roden Bill and Sue Rodgers Rodman Natural Resources Mr. and Mrs. Mark E. Rodriguez Mr. and Mrs. James C. Roe Mr. Don P. Roesle Ms. Shannon F. Roethemeyer Mr. and Mrs. J. Hugh Roff, Jr. Mrs. Ann V. Rogers Mr. Clarence B. Rogers Mrs. Donna L. Rogers Mr. Hamilton Rogers Mr. and Mrs. J. Dickson Rogers Joelle G. Rogers Ms. Kathy Rogers and Mr. Andrew J. Sugalski Ms. Kay Willis Rogers Regina Rogers

Mrs. Sandra M. Rogers Mr. Steve K. Rogers Mr. and Mrs. William F. Rogers The Rogers Agencies, Inc. Rogers Corporation Mary and E. P. Rogers Foundation Mr. Daniel Roh The RoKe Foundation, Inc. J. Patrick and Lynne Rolla Mr. Robert L. Roloff Terry and Bert Romberg Mrs. Jacqueline E. Rome Roof Doctor Rooster Petroleum, LLC Mr. William H. Roquemore Mrs. Ruth E. Roschke Dr. Bob Rosebrock Mr. John S. Rosebrough Mr. and Mrs. Norman C. Rosen Dr. A. Everett Rosen & Ruth E. Rosen Foundation Mr. and Mrs. Leonard B. Rosenberg Mr. and Mrs. Leonard C. Rosenberg E. Jay Rosenstein Dr. and Mrs. Joseph Rosenstein Rozanne and Billy Rosenthal Mr. and Mrs. Robert M. Rosenthal Rosenthal Companies The Marion & Robert Rosenthal Foundation Mr. David N. Rosner David N. Rosner Charitable Foundation Mr. and Mrs. Allan Ross Estate of Caroline A. Ross Mr. David J. Ross Mr. and Mrs. James E. Ross Dr. and Mrs. Robert Ross

Mr. William F. Ross Mrs. William H. Ross Mr. Robert Rossen Mrs. Jane Anderson Rote Mr. Jim C. Roth Mr. and Mrs. Anthony Rotondo Mr. and Mrs. Tyler W. Rounding Rowan Companies, Inc. Arch and Stella Rowan Foundation, Inc. Mr. and Mrs. James W. Rowe Mr. and Mrs. John F. Rowsey Roy Gurley Oil & Gas Mr. and Mrs. Jerry Rubenstein Jerry and Maury Rubenstein Foundation Mr. Robert G. Rubin Michael Rudelson and Kathleen Gallagher Nancy and Clive Runnells The Nancy and Clive Runnells Foundation Estate of William A. Runnels III Damon Runyon Cancer Research Foundation Mr. and Mrs. Laloo G. Rupani Mr. and Mrs. Edward J. Ruppert Mr. W. Marvin Rush Mr. and Mrs. L. Giles Rusk Lynn and John Russell Mr. and Mrs. John L. Russell Estate of Maydel Dean Russell Mrs. William O. Russell, Jr. Mr. and Mrs. Paul Rutenis Paul Rutenis Research Fund Keith and Christa Rutherford Mr. and Mrs. Patrick R. Rutherford, Jr. Rutherford Oil Corporation

RWM Foundation Kathryn and Patrick W. Ryan Ryder Scott Company, L.P. Dr. Charles C. Ryrie The Ryrie Foundation Mr. and Mrs. Jin Roy Ryu Gita and Ali Saberioon Mr. Andrew E. Sabin Andrew Sabin Family Foundation Saco Energy, Inc. Mr. Dale A. Sadler Safeway Inc. Mr. Hanna F. Sahliyeh Saks Incorporated Mrs. Frances Saladin Mr. and Mrs. Frank J. Saldaña, Jr. Mr. and Mrs. Mark J. Saleski Mr. and Mrs. Leif R. Salvesen Mr. and Mrs. John A. Salzer III Sam Kane Beef Processors, Inc. Dr. Jean Samaan Mr. Kelton D. Sams Samson Resources Company San Antonio Area Foundation Mr. and Mrs. A. R. Sanchez, Jr. Mr. and Mrs. Adalio T. Sanchez The A. R. Tony and Maria J. Sanchez Family Foundation Sandbaggers Inc. Estate of Alberta Elaine Sander Estate of Virginia Weyerman Sander Mrs. Cela W. Sanders Mr. and Mrs. Don A. Sanders Mr. and Mrs. William L. Sanders Mr. and Mrs. Roy I. Sandoval Ms. Kathy G. Sandridge Sands Investment, Ltd.

Monroe Dunaway Anderson Society New members, Sept. 1, 2007-Aug. 31, 2008 Established in 1995, the Monroe Dunaway Anderson Society recognizes individuals and families who have selected the programs at M. D. Anderson to benefit from a planned gift, such as a bequest, life insurance policy or other similar vehicle. Listed here are new members of the society who recently named the institution in their estate plans. Mr. and Mrs. Jerry Abbott Estate of John L. Anderson, Jr. Estate of Johnnie M. Anderson Ms. Dusty Baker Estate of Irma Bass Ms. Mary B. Booth Estate of Charlie Boyd Estate of Sylvia H. Brown Mr. Steven S. Bush Estate of Kathleen C. Cailloux Estate of Cherie Glynn Franks Carver Estate of Leonard H. Childress Mr. Stephen M. Coleman Estate of Kathleen Conn Estate of Allie Crockett Conway, Jr. Mr. and Mrs. James M. Cook Estate of R.W. Cooper Mr. and Mrs. Decker Dawson Mrs. Elizabeth A. Decker Mr. and Mrs. Tom DiCenso Mrs. Muriel P. Dowe

Ms. Candas A. Erickson Mrs. Fay Cohen Friedman Mrs. Geraldine H. Gerling Ms. Frances E. Ginsburg Estate of Royce A. Glidden Mr. F. O’Neil Griffin Mr. and Mrs. Richard Grossman Ms. Sandra D. Grossman Ms. Edith T. Harris Mr. Edgar M. Hood, III Mrs. Letha K. Hudson Mr. and Mrs. William R. Jeffryes Estate of Barbara M. Johnson Mrs. Charlene A. Johnson Mr. Darrel D. Johnson Estate of Larry Johnson Estate of Leona V. Jones Mr. and Mrs. Thomas L. Kazokas Mrs. Rose Mary Kennedy Estate of Willet Keyser Ms. Martha R. Kleymeyer

Estate of Lois Kuss Mr. and Mrs. Philip H. Lanham Estate of Michael G. Lawrence Estate of Elsie Lieskovsky Estate of Kathy A. Loera Mrs. Betty Lunsford The Honorable and Mrs. Frederic Malek Estate of Alma Lee Marshall Mrs. Wanna McCorkell Mrs. Gail P. Middlekauff Estate of Jerome J. Nerenberg Estate of Lawrence E. Nix Estate of Emae Miller Patin Mr. and Mrs. Walter L. Patrick Estate of Frances M. Polansky Mrs. Susan S. Pratt Estate of Bruce A. Redwine Estate of Evelyn Marie Reno Mr. James C. Roe Mr. Robert G. Rubin Mr. Hank Sarkis

Mrs. Brenda K. Schultz Estate of Rana Sellers Estate of Virgil Edward Settle Estate of Virginia L. Simien Estate of Oriel A. Snyder Estate of Langford Spraggins Mr. Edward D. Stone, Jr. Mrs. Doris E. Sula Mrs. Carlys K. Swenn Mr. Lawrence E. Tabak Mr. Steve L. Thomas Estate of Helen A. Trahin Mr. George T. Van Horn, Jr. Eugenia B. Walker Estate of Rosalie Westbrook Mrs. Marjorie Wolf Daisy S. Wong and Alden Wong

Partners in Making Cancer History® George and Jennifer SanFilippo sanofi-aventis U.S. Mr. Dennis A. Sanvi Sarcoma Research Foundation Mr. and Mrs. Christopher Sarofim Mrs. Louisa Stude Sarofim Mr. and Mrs. Laurence R. Saslaw Dr. and Mrs. William C. Satterfield Dr. Priscilla P. Saunders Mr. and Mrs. Dan C. Savage Mr. and Mrs. Alford C. Savoie Dr. Raymond Sawaya Mr. Roy R. Sawyer II Mr. Kyle J. Scaff Mr. and Mrs. Joe H. Scales The Joan Scarangello Foundation Ms. Laura B. Scarbrough Mr. Dan E. Scarlett Mr. and Mrs. Joseph N. Scarpinato Mrs. Ted Schad Mr. and Mrs. Donald J. Schade Mr. John T. Schalk Mr. Jack W. Schanck The Schanen Family Mr. and Mrs. Wayne F. Schaper, Sr. Dr. and Mrs. Steven J. Schapiro Mr. and Mrs. Dwight C. Schar Mr. and Mrs. Glenn A. Scharp Mr. and Mrs. Andrew A. Schatte Mr. and Mrs. Kenneth I. Schatz Mr. and Mrs. Matthew K. Schatzman Mr. and Mrs. Daniel J. Scheffer Mr. David R. Scheihagen Schering-Plough Foundation Mr. and Mrs. Robert and Janelle Scheuer Ms. Linda D. Schibi Bob and Patricia Schieffer Mr. Donald T. Schlattman Mr. and Mrs. Thomas A. Schleigh, Jr. Mr. and Mrs. Pierre M. Schlumberger Schlumberger Technology Corporation Ms. Susanne M. Schmelz Mr. Edwin Schmid Mr. Arthur W. Schmidt Mr. and Mrs. Paul B. Schmidt Mr. and Mrs. Richard W. Schmidt Father Joseph J. Schmitt Schnabel Foundation Company The Honorable and Mrs. Harvey A. Schneider Mr. and Mrs. William Schneider Mr. and Mrs. Douglas W. Schnitzer Mrs. Hugo W. Schoellkopf III Mr. Joe R. Schoen Mr. William L. Schoen and Mrs. Michelle Comeau Dr. Scholl Foundation Mr. and Mrs. Richard D. Schreiber Mr. and Mrs. Bruce H. Schremp Mr. and Mrs. J. P. Schroeder Colonel Eldor H. Schueler Mrs. Betty Schultz Mrs. Brenda K. Schultz Mr. and Mrs. Timothy A. Schultz Edith and Bob Schumacher Mrs. Kathryn L. Schutts Schwab Charitable Fund Mr. and Mrs. Barry K. Schwartz Richard and Beth Newburger Schwartz Barry K. Schwartz Family Foundation Mr. and Mrs. Charles N. Schwarz, Jr. The Scienomics Group Dr. and Mrs. Alastair I. Scott Mrs. Barbara W. Scott Mr. and Mrs. Charles Red Scott Mr. and Mrs. Craig Scott Mrs. Nancy J. Scott Mr. Thomas D. Scott The Thomas H. and Mayme P. Scott Foundation, Inc.

Mr. and Mrs. Nick Scotto Kim and Jeff Scrivener Scurlock Foundation Mr. and Mrs. Leo W. Seal, Jr. Mr. Albert L. Seaver Mr. and Mrs. Edward C. See Seecure, LLC Mr. and Mrs. Ray R. Seegmiller Mr. and Mrs. Alvin G. Segel Ms. Courtney L. Seger Mr. and Mrs. Larry J. Seger Ms. Lauren N. Seger Mr. Mark A. Seger Mr. Phillip J. Seger Mr. and Mrs. Thomas W. Seger Mr. and Mrs. Thomas B. Sehon, Sr. Mr. and Mrs. David L. Seida Mrs. Elaine Seidel Ms. Sharlotte Seidel Mr. and Mrs. Philip W. Seidenberger Seismic Exchange, Inc. Lawrence K. Selan and Sharon Fortmeyer-Selan Dr. John W. Sellers Sell-Thru Services, Inc. Mrs. Suzanne D. Sen The Sence Foundation Sense Corp Texas 4000 for Cancer Sentient Jet, Inc. Sephora USA, Inc. Sepracor Serono Inc. Mr. and Mrs. James A. Serritella Mr. and Mrs. Vernon A. Sevier, Jr. Mr. and Mrs. Carl Sewell Sewell Automotive Companies Sewell Village Cadillac Mr. and Mrs. John Sexton SGS Industrial Supplies Mr. and Mrs. William C. Shackelford Mr. and Mrs. Bobby S. Shackouls Shackouls Family Foundation Mr. and Mrs. Peter H. Shaddock Mr. and Mrs. Peter H. Shaddock, Jr. Mr. and Mrs. William E. Shaddock Mr. Ronald G. Shafer Mr. and Mrs. Mel A. Shaftel Mr. and Mrs. Leonard A. Shankle Mrs. Howard S. Shanks, Jr. Mrs. Susan Shannon Shanok Foundation Inc. Mr. and Mrs. Marc J. Shapiro Mr. and Mrs. Marvin L. Shapiro Mr. and Mrs. H. J. Sharratt Mr. and Mrs. James A. Shaughnessy Rosemary and Joseph Shaughnessy Mr. and Mrs. Paul J. Shaughnessy Mr. John K. Shaw Mr. and Mrs. Randall S. Shawell Mr. James H. Shea Shea Physical Therapy P.C. Mr. and Mrs. Charles E. Sheedy The Sheedy Foundation Mr. and Mrs. Myron M. Sheinfeld Mrs. Jeanne F. Shelby Mr. Patrick B. Shelby Shell Oil Company Foundation Shell Pipeline Company LP Mrs. Beatrice M. Shelly and Family Mr. J. N. Shelton Louis and Ouita Shelton Mr. and Mrs. Simon Shen Mrs. Lucille Sheng Mrs. Betty Jean Shepherd Ms. Cynthia S. Sheridan Sheridan Production Company Mr. and Mrs. George V. Sherman, Jr. Sherman Foundation Trust Mr. and Mrs. Russell Sherrill Mr. and Mrs. Richard Sherry Ms. Myrtis E. Shiftar Mr. Scott A. Shine

Dr. Daniel Shirey Mr. John S. Shivers, Sr. Mr. and Mrs. Derek W. Shoobridge The Liddy Shriver Sarcoma Initiative Mr. and Mrs. Grady Lee Shropshire Ms. Jennifer L. Shufelt and Mr. Colter Harris Ms. Evelyn W. Sibley Sico, White & Braugh, L.L.P. Mr. Howard Sides Sidney Frank Importing Co., Inc. Ms. Elizabeth Sieg Siemens Caring Hands Foundation Siemens Medical Solutions USA, Inc. Siemens Petnet Solutions, Inc. Sierra Resources Inc. Mr. and Mrs. David G. Siers Mr. and Mrs. Gerald R. Sigal Sigma International SignMeUp.com Ms. Heather Silver and Mr. Neil D. Grundhoefer Silver Eagle Distributors, LP Mr. and Mrs. Morton L. Silverblatt Estate of Virginia L. Simien Mr. and Mrs. Harold C. Simmons Mr. and Mrs. Laurence E. Simmons Matthew and Ellen Simmons Mr. and Mrs. Neal O. Simmons Mr. Tony A. Simmons Simmons & Company International Neal O. Simmons Foundation Virginia and L. E. Simmons Foundation Mr. and Mrs. Ronald A. Simms The Simms/Mann Family Foundation Mr. and Mrs. J. Peter Simon William E. Simon Foundation, Inc. Simon Property Group, LP Ms. Sydney Simons Mr. and Mrs. Geoffrey N. Simpson Mr. Henry Simpson Mr. William Simpson Ms. Cheryl Sinclair Estate of Lola Margaret Sinclair Mr. and Mrs. Don B. Singer Mr. and Mrs. William A. Sippy Mr. and Mrs. John J. Sisler Ms. E. R. Sisson Mr. and Mrs. Robert S. Sizemore SK Foundation Mr. and Mrs. M. L. Skaggs Mr. and Mrs. Michael B. Skalka Mr. Gary Skarke Mr. and Mrs. Damir S. Skerl Mr. and Mrs. J. W. Skidmore Mr. and Mrs. Louis Skidmore, Jr. Ms. Lillian S. Skiles Mr. and Mrs. Sam Skinner Mr. Jack Skufca Mr. and Mrs. Eugene Slater Mr. and Mrs. John R. Slavinsky Mr. and Mrs. Gene Sledge Mr. and Mrs. Jack W. Sledge Mr. and Mrs. Gerald L. Sliger Mrs. Barbara J. Sloan Mr. and Mrs. Melvin Sloan Mr. and Mrs. Albert H. Small Mr. and Mrs. Robert I. Small The Albert & Lillian Small Foundation Mrs. Susan M. Smauder Mr. and Mrs. Frank M. Smeal Mrs. Judith B. Smerlis Smikis Foundation Alan and Michelle Smith Dr. Alfred R. Smith Mrs. Barbara G. Smith Mr. Brett Smith Mr. Brian J. Smith Mr. and Mrs. Bruce B. Smith Mr. and Mrs. Bubba Smith Mr. and Mrs. Byrom J. Smith III

Mr. Chadbourne B. Smith Mr. and Mrs. Dick Smith Mr. Donald A. Smith Mr. and Mrs. Ed A. Smith Ms. Elizabeth D. Smith Mr. and Mrs. Ford Smith Mr. and Mrs. Gerald B. Smith Mr. and Mrs. Greg Smith Mr. Henry A. Smith, Jr. Mrs. Jack Smith Mrs. Jean C. Smith Mr. Jim R. Smith Joe H. Smith and Kent H. Smith Mr. and Mrs. Kent H. Smith Mr. and Mrs. L. R. Smith Mr. and Mrs. Lance Smith Mrs. Lura B. Smith Mr. and Mrs. Marvin L. Smith Mr. Noel E. Smith, Jr. Norma and Harvey Smith Onnie Leach Smith Mr. Randlow Smith Mr. and Mrs. Robert B. Smith, Jr. Mr. and Mrs. Robert L. Smith Rodney A. Smith Mr. Scott Smith Mr. and Mrs. Stephen F. Smith Mr. and Mrs. Stewart Smith Mr. Terence J. Smith Mr. and Mrs. Thomas S. Smith Mr. and Mrs. Warren H. Smith Mr. and Mrs. William F. Smith Mr. and Mrs. William R. Smith Clara B. & W. Aubrey Smith Charitable Foundation Gordon V. and Helen C. Smith Foundation Vivian L. Smith Foundation The William A. and Madeline Welder Smith Foundation Smith International, Inc. Mr. and Mrs. Thomas M. Smouse Mr. and Mrs. Robert G. Snead Mr. and Mrs. Robert M. Snell Mr. and Mrs. Thomas M. Snell Mr. John A. Snider Mr. and Mrs. Kevin Snodgrass Mr. Brian Snoek Mr. and Mrs. Harold B. Snyder Mr. John C. Snyder Mr. and Mrs. Louis J. Snyder Nancy and John Snyder Foundation Soft Imaging, LLC Nancy and John Solana Advised Fund of The Dallas Foundation Dr. Patricia Solar and Mr. J. Michael Solar Mr. and Mrs. Robert A. Solberg Dr. and Mrs. Khalid Rashid Soleja Dr. and Mrs. Kenneth A. Somberg The Somekh Family Foundation Mrs. Terry Sonnevil Mr. and Mrs. Claude Sonnier SonoSite, Inc. Mr. and Mrs. Thomas F. Soriero, Sr. Mr. Charif Souki Mr. Charles M. Sours South Corpus, Inc. South Texas Money Management, LTD. Southern Company Southern Mazda Allied Car Club Southside Market & BBQ, Inc. Southwest Airlines Co. Southwest Ocean Services, Inc. Southwestern Energy Company Mr. and Mrs. Rodney A. Sovereign Mr. and Mrs. Brent Spaeth Mr. and Mrs. Bill J. Sparks Ruth Parr Sparks Foundation Dr. Ashley Speckhart Mrs. Heather F. Spector Spectra Energy Foundation

Spectrum Global Fund Adminstration LLC Mr. Roger W. Speer Mr. William T. Speller Mr. and Mrs. Ron J. Spellman Mary John Spence Mr. and Mrs. Ralph Spence, Jr. Ms. D. Laurie Spencer Mr. and Mrs. George W. Spencer Mr. and Mrs. Melvin D. Spencer Spencer Stuart Mr. Lee W. Spieckerman Mr. and Mrs. Joel I. Spira The Joel & Brenda Spira Foundation Dr. Craig A. Spletzer Mrs. Mary F. Spletzer Mrs. Mauri Sponagle Sports Endeavors, Inc. Mr. and Mrs. Dale E. Spradley Estate of Langford Spraggins Dr. and Mrs. James B. Sprague Mr. and Mrs. H. J. Springer Mr. and Mrs. Michael Sprintz Mr. Jack B. St. Clair Mr. and Mrs. C. P. St. Laurent St. Paul’s Episcopal Church St. Philip the Apostle Catholic Church Ms. Kristy L. Stager Mr. Lowell I. Stahl Dr. Matthew J. Stahl Mrs. Margaret Dailey Stallings Mr. Johnson L. Stambaugh Mrs. Rosalie Stanke-Garvin Mr. and Mrs. Charles B. Stanley Mr. and Mrs. R. John Stanton, Jr. Mr. Michael L. Stanwood George and Hilde Stapleton Lois and George Stark Mr. Jeffrey G. Stark Mr. and Mrs. Morris C. Stark State Employee Charitable Campaign State Farm Companies Foundation Ms. Sharon Werlin Staton Mr. and Mrs. Robert W. Stearns Mr. Jeff Steen Sharon Steen Mr. and Mrs. Will L. Steeves The McKaila J. Steffes Foundation Mr. and Mrs. Michael J. Stehling Mr. and Ms. Gary W. Stein Mr. and Mrs. Phil O. Steinberg Ron and Phyllis Steinhart Dr. Fred Steinman and Mrs. Robyn Steinman Mr. John D. Stenson Stephanie Johnson Triathlon Mr. and Mrs. Carl M. Stephens Mr. and Mrs. Roderick D. Stepp Mr. Norm Steppe Sterling Bank Sterling-Turner Foundation The Steven B. Schonfeld Foundation, Inc. Steven M. Seger Memorial Foundation, Inc. Ms. Rena Stevens Mr. John Stevenson and Ms. Robyn Rothman Mr. and Mrs. Jed Stever Mr. and Mrs. H. Leighton Steward Mr. and Mrs. Douglass M. Stewart Dr. and Mrs. Richard B. Stewart Mr. and Mrs. Ward W. Stewart Mr. Lawrence R. Stiles Mr. and Mrs. James R. Stimmel Mr. and Mrs. J. Michael Stinson Mr. and Mrs. Kirk Stinson Mr. and Mrs. Robert B. Stobaugh Mr. Michael M. Stoeger Mr. and Mrs. Don Stojanik Mr. and Mrs. Steven Stoltz Mr. and Mrs. Edward D. Stone, Jr. Mr. and Mrs. Gregory R. Stone

M. D. Anderson Annual Report 2007-2008 Sheri Hirschfield Stone Mr. Robert E. Storey, Sr. Mrs. Lynda Stotsky Louis L. Stott Foundation Mr. and Mrs. Earl D. Stout Mr. and Mrs. Norman D. Stovall, Jr. Mr. George C. Stradley D. W. Strahan Strake Foundation Charlotte and Terry Strange Stratus Properties Inc. Mr. F. W. Straw Mr. and Mrs. Bruce Street, Jr. Jannette and Gerald Streit Robert Strickland Family Foundation Dr. and Mrs. David R. Strome Mr. and Mrs. Steven C. Stryker Stryker Mr. Ben R. Stuart Mr. Michael D. Stuart Mr. Timothy L. Stuart The Stuart Charitable Foundation Mr. and Mrs. James E. Stueve Mr. and Mrs. Mike P. Sturdivant, Sr. Mr. William T. Sturgis Mrs. Lucinda C. Subers Mr. and Mrs. Calvin H. Sugg, Jr. Mr. and Mrs. Joe J. Sula, Jr. Mr. and Mrs. Gerald Sullivan Mrs. Jeanne M. Sullivan Nancy S. Sullivan Mr. and Mrs. Robert L. Sullivan Ms. Teresa A. Sullivan and Mr. H. Douglas Laycock Estate of Nancy Irene Sultuska Mrs. Betty J. Summitt Mr. Joe Chat Sumner III Mr. Cal Sumrall Mr. and Mrs. Carl T. Sundbeck, Jr. Mr. Charles Sunderland The Sunderland Foundation Mrs. Margaret C. Sunderman Sundog Southwest SuperDimension, Inc. Superior Energy Services, Inc. Superior Structures, Inc./Beshara Harb Mrs. Dolores L. Sura Sutaruk Foundation Mr. and Mrs. Rod Sutherland Mr. Frank E. Suttles Mr. James D. Sutton Ms. Lisa Sutton Mr. and Mrs. Richard A. Sutton Mr. and Mrs. Douglas E. Swanson, Jr. Mrs. Alice M. Sweeney Mr. and Mrs. John W. Sweeney III Mrs. Carlys K. Swenn Mr. and Mrs. Karl F. Swenson Mr. and Mrs. Virgil N. Swift Ms. Janet L. Swikard and Mr. Joe R. Davis Dr. Richard D. Swope Symphony Capital LLC Syndax Pharmaceuticals, Inc. SYSCO Corporation Mr. and Mrs. Antonio M. Szabo Mr. Charles W. Szuluk Mr. Lawrence E. Tabak Mrs. Elizabeth Y. Taber Mr. and Mrs. Albert S. Tabor, Jr. Mr. and Mrs. Ali Taghdisi The Tagliaferri Foundation Takeda Pharmaceuticals North America, Inc. Sharon and J. Michael Talbert Mrs. Zoe Talbert Mr. and Mrs. Tony L. Talbott Mr. G. R. Talley Mr. and Mrs. Kevin D. Talley Ms. Margaret Talley

The first Avon Walk for Breast Cancer in Houston, April 12-13, 2008, raised $1.9 million for breast cancer programs in the Houston community. M. D. Anderson was awarded $330,000 to expand its patient navigation and breast health education services to underserved populations at Lyndon B. Johnson General Hospital. The institution provides oncology physician staffing and leadership at the hospital. Mr. and Mrs. Robert M. Tallman Bob Tallman’s Charities, Inc. Mr. Bruce A. Tankleff Tanner Foundation TAP Pharmaceuticals Inc. Mr. and Mrs. Alan S. Taper Mrs. Beatrice B. Taplin Mrs. Polly T. Taplin Target Insurance Services Mr. and Mrs. Paul Tashman Judy and Charles Tate The Charles W. Tate and Judy Spence Tate Charitable Foundation Taub Foundation George and Bonnie Taubel Mr. and Mrs. Jerry Tauber and Family Ms. Caryn L. Taurog Mr. and Mrs. Billy Tauzin Richard and Leanne Tavoso Tax Assessor Collectors Association Mrs. Catherine B. Taylor Mr. John S. Taylor Ms. Kim Taylor Mr. David M. Tehle Teleflex Arrow International, Inc. Mr. and Mrs. Thomas J. Tella II Mr. and Mrs. Howard T. Tellepsen, Jr. Buddy and Ellen Temple Mr. and Mrs. Larry E. Temple T.L.L. Temple Foundation Mr. Robert N. Tenczar The Tensar Corporation Tenton Industrial Construction, Inc. Tepco LLC Tex US TOO Texas Academy of Family Physicians Texas Aromatics, LP and Melbern G. Glasscock Texas Asian Foundation in honor of Thurmond Woodard Texas Capital Bancshares, Inc.

Texas Federation of Business & Professional Women Foundation Texas Heavy Equipment Sales, LLC Texas Instruments Foundation Educational Matching Texas Medical Center Fleming and Davenport Funds Texas Neurofibromatosis Foundation Texas Prairieland Foundation Texas Welders Supply Co., Inc. TexGen Research Textron Charitable Trust TFWC Women’s Club of Kingsville TGS-NOPEC Geophysical Company Mr. Chester Allen Thames, Jr. THANC Foundation (Thyroid, Head and Neck Cancer) Theo’s Saddle & Sirloin Inn Dr. and Mrs. Richard L. Theriault Mrs. Castine Theriot ThermOptics Theta Charity Antiques Show Mr. and Mrs. Donald L. Thiel Mr. Edward E. Thiele Mr. Clay Thomas Mr. and Mrs. Dwaine M. Thomas Mr. and Mrs. Gillis Thomas Hedy W. Thomas Mr. John G. Thomas Joye D. Thomas Mr. and Mrs. William S. Thomas John G. Thomas Family Foundation Mr. and Mrs. Bill M. Thompson Mr. and Mrs. Brian J. Thompson Dottie and Jodie Thompson Mr. and Mrs. Hall W. Thompson Mr. and Mrs. Jon L. Thompson Mrs. Kathy Thompson Mr. and Mrs. Kelly R. Thompson Ms. Melodie I. Thompson and Mr. Laurence G. McEvoy Mr. and Mrs. Ned Thompson

Mr. and Mrs. Norman Thompson Ms. Patricia P. Thompson Peggy and Jere Thompson Mr. and Mrs. Randall M. Thompson Mr. and Mrs. Ronald M. Thompson Thompson & Knight Foundation Thompson Surgical Instruments, Inc. Dr. and Mrs. Kevin G. Thomson Mr. and Mrs. Wilfred F. Thorne Patrick J. and Loretta Thornton Dr. and Mrs. William E. Thornton Thorntree L.P. Ms. Mary L. Thorstenberg Mr. and Mrs. Brian Thurman Mr. William Thursby Mr. Rex W. Tillerson Tim Yochim Memorial Tournament Mr. and Mrs. William R. Timken, Jr. Timken Foundation of Canton Timken-Sturgis Foundation Mr. and Mrs. Cline A. Tincher Ms. D’Anna Tindal Ms. Cathy A. Tiner Tipton Asset Group, Inc. TIW Corporation, Inc. Dr. Teresa M. Todd and Dr. David L. Todd Mr. and Mrs. Bill Toller Mr. and Mrs. John L. Tomerlin Tony’s Prostate Cancer Research Tootsie’s Mr. David S. Topp Mr. and Mrs. Steve J. Torbeck Mr. and Mrs. Donaldo E. Torres Total E&P USA, Inc. Mr. and Mrs. Leon Toubin Town North Bank, N.A. Mrs. Sibyl V. Townes TracyLocke Tradition Financial Services Mr. Alan S. Trager Estate of Helen A. Trahin TransCanada

Mr. and Mrs. Paul K. Travis Trelleborg CRP, Inc. Triangle Services Mr. David A. Trice Mr. and Mrs. Carl J. Tricoli Mr. and Mrs. Walter H. Triebel Trinity Packaging Corporation Trio Electric Ltd. Mr. Gerard W. Trione Triten Corporation Tropical Trailer Leasing, LLC Dr. and Mrs. Barton C. Trover Mrs. Betty H. Trover J. M. Trow Mr. and Mrs. Brian K. Truby Mr. and Mrs. Dean B. Truitt Stephanie and Brad Tucker Tudor, Pickering & Co. Tulsa Community Foundation Turbo Components & Engineering, Inc. Mr. and Mrs. Ronald Turboff Mr. and Mrs. David O. Turner Mr. and Mrs. Lawrence A. Turner Turner Construction Turner Construction Company The Turner Corporation Estate of Robert G. Turney Turn-Tex Machine & Tool, Inc. Mr. Jack A. Turpin Mrs. Vernita J. Turpin Ms. Jean G. Tyner Mr. and Mrs. George H. Tyson, Jr. Mr. and Ms. H. Michael Tyson U.S. Endoscopy Group, Inc. U.S. Fiberglass Products, Inc. U.S. Quality Furniture Services, Inc. U.S.A. Sports, Inc. UBS Foundation USA Mr. Gary A. Ucella and Family Mr. and Mrs. D. R. “Tom” Uher Chip and Sara Underdown The Underdown Family Foundation 87

Partners in Making Cancer History® Mr. and Mrs. David M. Underwood, Sr. Mr. and Mrs. Timothy J. Unger Ms. Dorothy M. Ungerer Union Pacific Corporation United States Maritime Alliance Limited United Way Capital Area United Way of Greater Kansas City United Way of Greater Richmond & Petersburg United Way of the Capital Area United Way of Tri-State University of Michigan The University of Texas Health Science Center at San Antonio The University of Texas Houston Mr. and Mrs. W. J. Unverferth Urban Meridian Group, Inc. Uselton Family Foundation Colonel (Ret.) and Mrs. Roger R. Utley The V Foundation Mr. Dennis R. Vaillancourt Mr. and Mrs. Ken Valach Valco Instruments Company, Inc. Valeant Pharmaceuticals N. A. The Vale-Asche Foundation Valence Operating Company Jose L. Valencia, M.D. Dr. Alan D. Valentine Mr. Daniel Valentine Valuebank Texas Mr. and Mrs. Michael G. Van De Ven Mr. and Mrs. Frank J. Van Deventer Mr. and Mrs. Henri Van Dierdonck Mr. and Mrs. Roger E. Van Duzer Gene and Astrid Van Dyke Mr. George T. Van Horn, Jr. Van Kampen Investments Inc. Mr. and Mrs. Ronald D. Van Ness Van Scoyoc Associates Mrs. Thyrza Van Voris Mrs. Elizabeth W. Van Wagoner Mr. and Mrs. Tom Vance Dr. William R. Vance Mr. and Mrs. Johan P. Vanden Noort Gary and Debby Vandergriff Vanguard Charitable Endowment Program Mr. S. Wil VanLoh, Jr. Mr. and Mrs. William W. Vann The Vanneck-Bailey Foundation Mr. and Mrs. Adalberto Vara Mrs. Bradna B. Vardiman Varian Medical Systems, Inc. Susan and Gene Vaughan Mr. and Mrs. W. F. Vaughan Dr. and Mrs. Leonel Vela Mr. and Mrs. David R. Venarge Mr. Michael Venus Mr. and Mrs. William P. Verbout Dr. Kathleen S. Verderber and Dr. Rudolph F. Verderber D. R. “Sid” Verdoorn Verizon Foundation Ms. Mary Shelton Simpson Vescovo Mr. and Mrs. Greg M. Vesey Mr. Samuel H. Vester, Jr. Veterans of Foreign Wars Herbert D. Dunlavy Post 581 Ms. Frances B. Vick Vick Family Foundation, Inc. Vicon Equipment Inc. Helen R. Viereck Sam Viersen Family Foundation, Inc. Mrs. George F. Vietor Mr. and Mrs. Ricardo Villarreal Viropharma Incorporated Vital Care Charitable Foundation Inc.

Mr. and Mrs. Joseph V. Vittoria Mr. and Mrs. A. J. Vogel Mr. and Mrs. Gregory A. Vogt Mrs. Wilma Voss Mr. and Mrs. Mark L. Waage Wabash Valley Produce, Inc. Wachovia Wachovia Foundation Matching Gifts Mr. and Mrs. Richard L. Wade Susan Roberson Wade Memorial Car Rally Mrs. Cuba Wadlington, Jr. Mr. and Mrs. Robert Waechter Mr. and Mrs. J. Virgil Waggoner Mr. and Mrs. Andrew D. Wagner Mr. and Mrs. Cyril Wagner, Jr. Dr. and Mrs. K. James Wagner Mr. and Mrs. Philip H. Wagner Mr. and Mrs. Willard B. Wagner Mrs. Mary Pillsbury Wainwright Wake Radiology Oncology Services The Honorable and Mrs. Stephen A. Wakefield Mrs. Charlie Walden Ms. Jane M. Waldkirch Sharon and Bob Waldron Mr. and Mrs. Kirby D. Waldrop Mrs. Barbara H. Walker Mr. Foster Walker III Mr. and Mrs. Foster Walker III Mr. Ralph Walker Mr. Weldon Walker Mrs. Sharon Borg Wall Mrs. Dwane L. Wallace Ms. Ellen J. Wallace and Mr. Mitch Kreindler Mr. and Mrs. H. Dalton Wallace Wayne and Margaret Wallace Wal-Mart /Sam’s Club Foundation Walsh Charitable Trust Mr. and Mrs. John T. Walter, Jr. Mr. and Mrs. Joseph C. Walter III Mr. and Mrs. Edward J. Walters, Jr. Mr. and Mrs. DeWitt Waltmon Mrs. C. Lee Walton Ms. Qingsu Wang and Mr. John G. Zvonar Mr. J. E. Wann Wapiti Operating, LLC Mr. Albert J. Ward, Jr. Mr. and Mrs. Charlie Ward Mr. and Mrs. William C. Ward Richard Ware The Ware Foundation Mr. and Mrs. John A. Warner Regina and Arthur Warren Mr. and Mrs. F. Morgan Warzel Employees of Washington Mutual Steve and Sally Wasserman The Bert & Sandra Wasserman Foundation Waste Management, Inc. Mr. and Mrs. David S. Watkins Mr. Eddie Watson Mr. James Watson Mr. and Mrs. Robert M. Holmes Ms. Marie Watts Ms. Marilyn Kay Watts Waukesha-Pearce Industries, Inc. Mr. Richard T. Wax Ms. Teresa A. Wayne Mr. and Mrs. Andrew Weaver Mr. F. Rene Weaver Mr. and Mrs. Philip F. Weaver The Gil & Dody Weaver Foundation Mr. and Mrs. John R. Webb Mr. and Mrs. Michael R. Webb Mr. and Mrs. W. Temple Webber, Jr. The Webber Foundation Mr. and Mrs. Anthony K. Weber Mrs. Patricia A. Weber

Weber Family Foundation Mr. and Mrs. William M. Webster IV Timothy R. Weddle Mr. and Mrs. James P. Weidener Mr. Peter E. Weidler Mr. and Mrs. Kenneth M. Weil Mr. and Mrs. S. Conrad Weil, Jr. Mr. and Mrs. David Weinberger Dr. Edwin Weinfield Weinfield Family Foundation The Weingarten Schnitzer Family The Weingarten Schnitzer Foundation, Inc. Emily Weingarten-Stein Mr. and Mrs. Kevin F. Weinrich The Weinstein Mitzvah Foundation, Inc. Mr. and Mrs. Michael Weintraub Joseph Weintraub Family Foundation Dr. and Mrs. Dan Weiser Ms. Laurie A. Weiss Mrs. Ruby R. Weiss Mr. and Mrs. David N. Welch Mr. and Mrs. G. Berkshire Welch The Robert A. Welch Foundation The Wellness Community-National Carole and D. Brent Wells Wells Fargo Community Support Campaign Mr. and Mrs. Eugene Werlin, Jr. Mr. and Mrs. Douglas E. Werner Mr. and Mrs. Steven L. Wessinger Mr. Bob West Ms. Judith West Ms. Marian E. West Mr. Milton H. West, Jr. West Michigan Christian Foundation Mr. Allen Wester Mr. Warren G. Wester Mr. F. Scott Westheimer Dr. Valda Kay Westmoreland Mr. Norden Wetstone Mr. and Mrs. R. Graham Whaling Mr. and Mrs. Patrick L. Whatley Mr. and Mrs. Edward Wheeler Mrs. Mae Dean Wheeler Mr. and Mrs. William M. Wheless III Mrs. Wilma P. Whitaker Mr. Bobby T. White Mrs. Cecile S. White Mr. and Mrs. John M. White Mr. and Mrs. Larry N. White The Honorable and Mrs. Mark White Ms. MaryAnn White Mrs. Raye G. White Mr. and Mrs. Richard W. White Mr. and Mrs. Russell W. White White Oak Energy, LLC Dr. and Mrs. John P. Whitecar, Jr. Mr. and Mrs. Howard M. Whitehead Mr. John J. Whitehead Mrs. Sue Trammell Whitfield Mr. and Mrs. Lowell D. Whitlock III Mr. and Mrs. Robert A. Whitman Mr. and Mrs. Don R. Whitten Mr. and Mrs. W. Gary Whittington Wieden + Kennedy Ms. Barbara Wilcox Mrs. Helen B. Wiley Mr. and Mrs. Michael E. Wiley Mrs. Dolores K. Wilkenfeld Mrs. Margaret M. Wilkerson Dr. and Mrs. W. Darrell Willerson, Jr. Mr. and Mrs. Bert B. Williams Ms. Beth Williams Mrs. Cheryl Lockton Williams Mr. and Mrs. Earle C. Williams Gene and Colleen Williams

Mr. and Mrs. J. D. Williams Mr. James N. Williams Mr. and Mrs. Joseph H. Williams Mr. Larry Williams Mrs. Margaret Alkek Williams Mr. Martin T. Williams Mrs. Michel H. Williams Mr. Ray R. Williams, Jr. Mr. and Mrs. Ray R. Williams III Mr. Rodney W. Williams Sheridan and John Eddie Williams, Jr. Mr. and Mrs. Thomas R. Williams Williams Companies, Inc. The Paul J. Williams Foundation Ms. Barbara J. Williamson Dr. and Mrs. Hugh J. Williamson Mr. and Mrs. Freddie L. Willie Mr. and Mrs. John C. Willingham Mr. James A. Willis Willis Management, Inc. Mary V. C. Wills WillSource Enterprise, LLC Ms. Helen B. Wils and Mr. Leonard A. Goldstein Mr. Clyde H. Wilson, Jr. Mr. and Mrs. Gerald M. Wilson Mr. and Mrs. Herman T. Wilson, Jr. Mr. and Mrs. James L. Wilson Ms. Karen King Wilson SuEllen and John Wilson Mr. and Mrs. Wallace S. Wilson Mr. and Mrs. M. Paul Winkler, Jr. Mr. Paul H. Winkler Mr. and Mrs. C. C. Winn Dr. J. David Winningham Ms. Elizabeth Winograd Mrs. Judith Winograd The Winokur Family Foundation, Inc. Mrs. Edwina H. Winter Mr. Tom G. Winterton Mr. and Mrs. John L. Wirth Mr. Paul Wirtzfeld Mr. and Mrs. William A. Wise William and Marie Wise Family Foundation Watson W. Wise Foundation Dr. David R. Witt II Dr. and Mrs. James F. Wittmer Mr. and Mrs. Brad Witty Mr. and Mrs. Gary I. Wolf Mrs. Marjorie Wolf Erving and Joyce Wolf Foundation Mr. and Mrs. Dan Wolfe Ms. Judith A. Wolfe Cyvia & Melvyn Wolff Mr. and Mrs. David S. Wolff Mr. and Mrs. Melvyn L. Wolff Wolff Family Foundation Mr. and Mrs. James W. Wolitarsky Woman’s Civic Club of Jasper Mr. and Ms. H. H. Wommack III Daisy S. Wong/JCorp. Mr. and Mrs. Pei-Fong Wong Mr. and Mrs. Don M. Woo Mr. and Mrs. Brian C. Wood Mr. and Mrs. David Wood Mr. and Mrs. Donald F. Wood Mr. and Mrs. Jackie D. Wood Mr. and Mrs. Jeffrey R. Wood Mr. Larry D. Wood Mr. and Mrs. Leonard W. Wood Mr. and Mrs. Gene M. Woodfin Mr. William G. Woodford Woodside Energy (USA) Inc. Mr. James P. Woodson Woodson Properties, Inc. Woolf Harris Incorporated Working Assets H. Lynn Worrall Mr. and Mrs. Terry N. Worrell

Henry N. Worrest Mrs. Marvin Z. Woskow Ms. Helen Wozar Mr. and Mrs. Albert Victor Wray Mr. and Mrs. Thomas W. Wren Estate of Roberta Wright Wright Asphalt Products Company, LLC Mr. Qiang Wu Mr. and Mrs. Michael G. Wyatt Wyeth Pharmaceuticals Xerox Corporation Mrs. Sue G. Yaffee Yahoo! Inc. Dr. Stacy A. Yamasaki Mr. and Mrs. Robert Yanover Mr. Fernando A. Yarrito Dr. James R. Yates and Dr. Alba A. Ortiz Mr. and Mrs. Kyle Yeates Sonia and Gary Yeck Mr. Michael W. York Mr. Dave Young Ms. DeLois C. Young Mr. John T. Young, Jr. Mr. and Mrs. Mark B. Young Estate of Nolan Young Dr. Paul Young and Mrs. Susan Torn Young Mr. and Mrs. Stephen M. Young Young Texans Against Cancer Mr. and Mrs. Steven M. Zager His Excellency Ardeshir Zahedi Mr. Henry Zarrow Mr. and Mrs. Jack Zarrow Mr. Stuart A. Zarrow Maxine and Jack Zarrow Family Foundation The Anne and Henry Zarrow Foundation Mr. Jeffrey C. Zaruba Dr. and Mrs. Alan P. Zeitlin Ferrin Randall Zeitlin Foundation for Sarcoma Research Dr. and Mrs. Brook Zemel Jori Zemel Children’s Bone Cancer Foundation Mr. and Mrs. Steven A. Zenthoefer Zeta Tau Alpha Foundation, Inc. Zeta Tau Alpha Houston Alumnae Association Dr. and Mrs. Lane D. Ziegler Mr. Paul Ziegler Mr. and Mrs. Robert C. Ziegler Mr. and Mrs. Tom Zimmerer Mr. Ronald R. Zimmerman Dr. Stuart O. Zimmerman Mr. and Mrs. Thomas W. Zimmerman Mrs. Susan G. Znameroski Mr. and Mrs. Joe Zuber Mr. and Mrs. Joseph F. Zullo Dr. and Mrs. Fernando J. Zuniga y Rivero Mr. X. Kembo Zunzanyika

Every attempt has been made to ensure the accuracy of this list. If an error has been made, please contact the Development Office at 713-792 -3450.

M. D. Anderson Annual Report 2007-2008

2007-2008 Data

Financial stability is key to ensuring continued progress toward Making Cancer HistoryÂŽ Carrying out M. D. Andersonâ&#x20AC;&#x2122;s mission requires us to be good financial stewards. Financial stability allows us to meet our commitment to providing the highestquality patient care, investing in the latest research and technologies, and serving as a superior teaching facility for future generations of health care professionals and scientists. As an agency of the State of Texas, we do not generate profits for the benefit of owners or investors. Instead, our total margin, budgeted at an average of 5 percent to 6 percent over the last five years, is used for the future needs of M. D. Anderson. These funds ultimately are returned to the community in the form of new and improved facilities and resources, more comprehensive patient care and prevention services, and continued progress against cancer through investment in research. Ensuring patients have access to cancer care is an important commitment in our mission. Charges for care provided to patients who participate in M. D. Anderson sponsored charity programs, or whose treatment was not fully covered by Medicaid, totaled more than $1 billion from Fiscal Year 2004 through Fiscal Year 2008. Maximizing our investment in each of our mission areas requires a careful balancing of resources. M. D. Anderson is committed to this responsible stewardship.

Data SOURCES OF REVENUE (unaudited) Gross patient revenue

FY 2004

FY 2005

FY 2006

FY 2007

FY 2008

$915,651,312

$993,930,120

$1,029,865,975

$1,164,683,028

$1,257,461,830

1,106,815,086

1,394,593,414

1,647,400,058

1,885,140,700

2,036,765,950

569,949,910

628,227,506

689,233,885

753,000,885

799,825,869

Inpatient services Includes nursing care, diagnostic tests, pharmaceuticals and patient care supplies

Outpatient services Services provided by clinics and departments for outpatient visits

Professional services Services provided by physicians in the treatment of patients

Amounts deducted from gross patient revenue Deductions from gross patient revenue Amounts discounted from established rates as a result of agreements with third-party payors, including Medicare, Medicaid and insurance companies. Also includes deductions associated with indigent care and bad debt.

1,239,313,575

Net patient revenue

$1,353,102,733

1,455,056,418

1,606,135,345

1,814,040,101

1,935,375,659

$1,561,694,622

$1,760,364,573

$1,988,784,512

$2,158,677,990

$234,049,515

$264,042,886

$289,957,497

$314,378,653

$374,765,267

147,941,738

140,770,734

158,529,119

160,130,024

167,894,635

15,936,074

19,325,115

22,876,625

25,319,457

26,514,386

23,205,830

12,365,641

20,832,995

29,369,564

38,374,559

80,739,008

108,685,555

101,368,135

161,853,840

(11,018,492)

$1,854,974,898

$2,106,884,553

$2,353,928,944

$2,679,836,050

$2,755,208,345

Restricted grants and contracts, philanthropy Includes funds received from state and federal agencies as well as donations from the public to support patient care, research, education and prevention missions

State appropriated general revenue Biennial appropriation of tax revenues by the Texas Legislature to support patient care, research, education and prevention

Auxiliary Funds received from parking fees, valet services, dining facilities, hotel charges, gift shop sales and vending machine sales

Other income Includes tuition and student fees, Childrenâ&#x20AC;&#x2122;s Art Project sales, management fees and other sources

Investment and other non-operating income Includes interest, change in market value, dividends, and gains and losses on sales of institutional property and equipment

Total revenue

M. D. Anderson Annual Report 2007-2008 USES OF REVENUE (unaudited) FY 2004

FY 2005

FY 2006

FY 2007

FY 2008

$257,627,595

$283,123,862

$341,540,289

$374,619,643

$414,772,468

68,027,985

80,162,189

135,029,784

138,970,358

146,620,811

1,034,302,015

1,149,309,045

1,194,110,713

1,323,426,531

1,435,254,577

220,394,235

273,125,533

330,029,490

345,418,403

400,706,162

145,875,926

163,022,318

173,716,186

187,197,744

203,649,311

128,747,142

158,141,606

179,502,482

310,203,371

154,205,016

$1,854,974,898

$2,106,884,553

$2,353,928,944

$2,679,836,050

$2,755,208,345

Research Expenses related to activities designed to impact our knowledge about cancer and the identification of novel treatments for patients with cancer

Instruction, academic support and public service Includes support of student services, scholarships and fellowships

Patient care Expenses directly related to the delivery of care to our patients, including medical supplies and pharmaceuticals, and the salaries and benefits of health care professionals

Facilities and depreciation Expenses for the use of buildings and equipment

Institutional support, auxiliary and other Includes support for parking, food and gift shop services, as well as general institutional support (e.g., information technology, human resources, administration, development activities, etc.)

Allocation to capital plan Funds allocated for future needs to replace and improve facilities and technology

Total expenses and allocation to capital plan

FY 2008 Sources of revenue

FY 2008 USes of revenue

(in millions)

$167.9 $38.4 $26.5

$146.6 $154.2 $203.7

$374.8

$400.7

$1,435.3

$2,158.7

$414.8

78.3%

Net patient revenue

52.1%

Patient care

13.6%

Restricted grants and contracts, philanthropy

15.1%

Research

6.1%

State appropriated general revenue

14.5%

Facilities and depreciation

1.4%

Other income

7.4%

Institutional support, auxiliary and other

1.0%

Auxiliary enterprises

5.6%

Allocation to capital plan

-0.4%

Investment and other non-operating income (-$11.0)

5.3%

Instruction, academic support and public service 91

Data Clinical profile

FY 2004

Hospital admissions

FY 2005

FY 2006

FY 2007

FY 2008

20,608

20,728

21,221

22,257

22,194

150,915

153,615

155,551

163,007

167,451

Average daily census

418

427

432

452

464

Average length of stay

7.3

7.4

7.3

7.5

Average number of operating beds

475

508

512

510

793,210

831,025

884,817

922,985

965,248

6,811,481

7,465,264

7,884,053

8,651,960

9,221,298

357,615

384,872

412,924

447,497

479,476

47,202

50,442

50,917

55,181

57,308

870

951

1,081

1,064

1,108

Patient days

Outpatient clinic visits, treatments and procedures Pathology/laboratory medicine procedures Diagnostic imaging procedures Surgery hours Total active clinical protocols

FY 2008 institutional data

Total employees 17,687

FY 2008 Gross Patient revenue by payor classification

(in millions)

$215.3

$97.8

Hospital-based volunteers 1,395

FY 2008 UNSPONSORED CHARITY CARE

$97.0

$2,481.4

$1,202.4

Faculty 1,469

60.6%

Managed care

29.4%

Medicare

5.3%

Other (international, self-pay, other)

2.4%

Medicaid

2.4%

Indigent

M. D. Anderson provided $208.7 million in unsponsored charity care to Texans with cancer in FY 2008.*

*Figure includes charges for care provided to patients who participate in M. D. Anderson sponsored charity care programs or whose treatment was not fully covered by Medicaid.

M. D. Anderson Annual Report 2007-2008 FY 2008 Total philanthropic support by type

Cash gifts

Amount

Corporations

$ 7,963,563

Foundations

21,475,889

Individuals

33,950,372

Organizations

2,687,619

Trusts and estates

5,371,778

FY 2008 total dollar gift amount

(in millions)

$210.0

$173.6

$134.8 Subtotal

$71,449,221

Pledge gifts* Corporations

$ 11,618,833

Foundations

66,843,519

Individuals

23,240,497

Organizations

11,266,466

Trusts and estates

25,311,014

Subtotal

$111.1

$103.5

$138,280,329 FY 2004 FY 2005 FY 2006 FY 2007 FY 2008

Gifts-in-kind Corporations

$162,148

Foundations

2,161

Individuals Organizations

FY 2008 total philanthropic gift supPort by purpose

129,137 $43.4 M

1,929

$13.2 M $124.0 K

Subtotal

Total

$295,375

$210,024,925

$153.3 M

*Pledge gifts are not reported here at net present value. Discounted value of planned gifts is $18,817,973.53.

72.9%

Research*

20.7%

Education/prevention/patient care

6.3%

Annual/unrestricted/undesignated**

0.1%

Capital facilities

*Donor-targeted gifts to research conducted in all mission areas. * *These dollars fund institutional peer-reviewed research.

Data Sources of research expenditures FY 2004

FY 2005

FY 2006

FY 2007

FY 2008

$150,528,693

$160,953,853

$182,028,411

$190,508,252

$194,889,144

22,338,298

26,766,196

28,020,431

34,307,882

40,625,360

39,050,337

43,062,200

49,678,964

61,086,784

73,518,196

$211,917,328

$230,782,249

$259,727,806

$285,902,918

$309,032,700

$13,944,763

$15,565,503

$15,163,811

$14,261,756

6,099,910

5,094,852

8,470,040

6,676,418

8,832,133

$20,044,673

$20,660,355

$23,633,851

$21,840,229

$23,093,889

$75,957,456

$84,111,416

$106,518,513

$116,719,735

$132,880,036

5,996,894

6,424,659

19,799,540

20,469,825

23,648,202

Total internal funding

$81,954,350

$90,536,075

$126,318,053

$137,189,560

$156,528,238

Total research expenditures

$313,916,351

$341,978,679

$409,679,710

$444,932,707

$488,654,827

External funding for research Federal grants and contracts Support for research provided through federal granting agencies such as the National Institutes of Health and the National Cancer Institute

Private industry grants and contracts Support for research grants provided through private corporations

Philanthropy and foundations Philanthropic funding provided specifically to support research initiatives and support for research grants provided through non-profit foundations Total external funding

State funding allocated for research State appropriated general revenue Support allocated to M. D. Anderson research activities by the State of Texas through the General Appropriations Act

Tobacco settlement receipts Expenditures funded by proceeds from the Tobacco Settlement and UT System-allocated Permanent University Fund to support research equipment Total state funding

Internal funding allocated for research Hospital operating margins Research expenditures supported by proceeds from the hospitalâ&#x20AC;&#x2122;s clinical activities

Institutional grants Philanthropic donations to the institution internally designated to support research and Physicians Referral Service funds internally allocated to support research activities

Education profile

FY 2005

FY 2006

FY 2007

FY 2008

922

979

958

977

1,043

1,221

1,421

1,365

1,452

1,536

Observers, visitors and special programs

382

481

607

715

600

Nursing students/rotations

498

778

836

1,727

1,778

Student programs

404

396

514

571

830

School of Health Professions programs

181

157

203

3,608

4,212

4,366

5,538

5,990

Clinical residents and fellows Research fellows

Total number of trainees 94

FY 2004

affiliations M. D. Anderson Cancer Center Orlando, Orlando, Fla.

The University of Texas System Board of Regents*

Centro Oncológico M. D. Anderson International España, Madrid, Spain

H. Scott Caven, Jr., Houston Chair James Richard Huffines, Austin Vice chair

M. D. Anderson Clinical Care Center in the Bay Area, Nassau Bay, Texas M. D. Anderson Radiation Treatment Centers in Bellaire, Fort Bend, Katy and The Woodlands, Texas; and Albuquerque, N.M.

Robert B. Rowling, Dallas Vice chair

Christus Spohn Stem Cell Program affiliated with M. D. Anderson Cancer Center Outreach, Corpus Christi, Texas

John W. Barnhill, Jr., Brenham James D. Dannenbaum, Houston Paul Foster, El Paso

Stephen C. Stuyck, vice president, Public Affairs

Printice L. Gary, Dallas

Sarah Newson, associate vice president, Communications

Janiece M. Longoria, Houston

Wendy Gottsegen, director, External Communications

Colleen McHugh, Corpus Christi

Executive Editor:

Benjamin L. Dower, Dallas Student regent

David Berkowitz, associate director, External Communications

Francie A. Frederick General counsel

Managing Editor: Sandi Stromberg, program manager, External Communications

*Appointments as of March 2, 2009

Writers:

The University of Texas System Administration

Francisco G. Cigarroa, M.D. Chancellor

David Berkowitz, Mary Brolley, Katrina Burton, Robin Davidson, DeDe DeStefano, Gail Goodwin, Erika Hargrove, Scott Merville, Julie Penne, Mary Jane Schier, Sandi Stromberg, Sarah Watson

Kenneth I. Shine, M.D. Vice chancellor

Designer: Michael Clarke

The University of Texas M. D. Anderson Cancer Center EXECUTIVE COMMITTEE

Photographers:

John Mendelsohn, M.D. President Thomas W. Burke, M.D. Executive vice president and physician-in-chief Raymond N. DuBois, M.D., Ph.D. Provost and executive vice president Leon J. Leach Executive vice president and chief business officer The University Cancer Foundation Board of Visitors OFFICERS

Ernest H. Cockrell Chair Nancy B. Loeffler Chair-elect

Betsy Carothers (page 59), John Everett (pages 5, 8,24,25, 28, 34, 55, 57), Eli Gukich (page 56), Michael Hart (page 1), Wendy Larsen/ISI Photos (page 58), Wyatt McSpadden (cover, pages 2-3, 7, 9, 12, 18, 22-23, 29, 32, 33, 36, 38, 39, 40, 44-45, 50 ), Gini Reed (pages 6, 13, 14 ), John Smallwood (page 27), F. Carter Smith (pages 15, 16, 17, 20, 21, 31, 40, 41, 43, 46, 47, 49, 51), Chet Snedden (page 76), Courtesy of the Avon Foundation (page 87), Courtesy of Linder & Associates (page 73) Conquest is published quarterly by The University Cancer Foundation Board of Visitors on behalf of The University of Texas M. D. Anderson Cancer Center. All correspondence should be addressed to the Division of Public Affairs - Unit 700, M. D. Anderson Cancer Center, 6900 Fannin St., Houston, TX 77030-3800, 713-792-3457. E-mail: sfstromb@mdanderson.org. Articles and photos may be reprinted with permission. For information on supporting programs at M. D. Anderson Cancer Center, please contact Patrick B. Mulvey, vice president, Development, 713-792-3450, or log on to the Development Office Internet site at www.mdanderson.org/gifts.

Ali A. Saberioon Vice chair Marc J. Shapiro Immediate past chair

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