COPHS News

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NEWS

This Issue: Research

Mercer is at the forefront in nanotechnology, drug delivery and cancer research. Page 6 A

P u b l i c a t i o n

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F r i e n d s

Faculty Essay

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Right Drugs,

Dean’s Column New Admissions Requirements

Right Patient

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Work Simulated The College’s new sim lab

b y : Kat h ry n M o m a r y

Pharmacists have long been using personalized medicine in the provision of patient care. We routinely considered body size, comorbid conditions, and drug interactions when assessing and recommending medication therapy for our patients. Now, we routinely do pharmacokinetic monitoring of medications to ensure patients are receiving the precisely correct dose. The very heart of personalized medicine is the RIGHT drug at the RIGHT dose for the RIGHT patient. However, a new term has recently become synonymous with “personalized medicine”—pharmacogenetics. Pharmacogenetics refers to the hereditary basis for inter-individual variation in drug response. We all have anecdotal experiences seeing patients have varied and unique responses to medications. A group of patients can receive the same drug; some will experience intolerable adverse effects while others

will gain no benefit at all. The objective of personalized medicine and pharmacogenetics is to identify those patients with aberrant drug response and treat them appropriately. Recently, the area of pharmacogenetics has been garnering a lot of attention. This is driven by several factors, but one of the most important is the Food and Drug Administration’s recent encouragement of voluntary genetic data submission with new drug applications. Specifically, this encourages the pharmaceutical industry to submit pharmacogenetic data beyond what is currently required in the drug approval process. The goal of voluntary genetic data submission is to help the FDA understand how to include genetic information in future regulatory decisions and prescribing information. There are currently 99 medications with pharmacogenetic information in their official label. This number will only continue to grow as more pharmacogenetic studies are done during the drug development process.

PT Residency Program

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News Briefs

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Faculty Essays What Can a PA Do for You? New Year’s Resolution? Ask A PT

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New Research Center Aims to Advance Drug Design, Discovery ATLANTA – The Mercer University College of Pharmacy and Health Sciences has launched a research center charged with designing new drugs and developing new computer-based design methods to advance novel drug discovery. The Center for Drug Design will focus on all aspects of drug design research and teaching, ranging from software development to the application of computer-based methods that will predict biologically active compounds prior to laboratory testing. The Center will serve as a resource for universities, industries, and agencies Dr. J. Phillip Bowen interested in new drug design and the enhancement of existing drug candidates. Using state-of-the-art computer technologies, Mercer’s new Center will become one of the premier academic facilities involved in drug design research, teaching and discovery. The Center will use powerful computers and sophisticated graphics workstations to pursue fundamental problems and methodologies at the interface of chemistry, biology and physics. In fact, several drugs currently on the market and used to treat various disease states were developed using similar computer-assisted drug design methodologies. Dr. J. Phillip Bowen, one of the nation’s leading scholars in the area of computer-assisted drug design, is the Center’s director. Bowen joined the College of Pharmacy and Health Sciences’ faculty this past August as a full professor in the Department of Pharmaceutical Sciences. He is the author of over 90 publications and several patents in the areas of organic, medicinal and computational chemistry, as well as computer-assisted drug design. Continued on page 3

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Right Dose,

pharmacogenetics: the newest tool in your tool kit

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Cancer Research Intensifies At College

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COPHS News is published biannually and provides the most current news and accomplishments of Mercer University’s College of Pharmacy and Health Sciences students, faculty and alumni. Please send your latest news and questions to: David Hefner Senior Director of Marketing and Communications hefner_dn@mercer.edu 3001 Mercer University Dr. Atlanta, GA 30341-4415 678.547.6244

President William D. Underwood, J.D. Dean & Vice President for the Health Sciences Hewitt W. “Ted” Matthews, Ph.D. Sr. Associate Dean Candace Barnett, Ph.D. Editor David N. Hefner Editorial Support Genice Johnson Shavonne Davis Design Cooperworks, Inc. Contributing Photographer Erik Lesser

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Student News

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PA Student Essay PT Student Essay

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PA White Coat Ceremony Calendar of Events In Memoriam

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Alumni News

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