Sanjeevita 2013

Sri Balaji Vidyapeeth

CIDRF

Annual Summit

Current Concepts in Integrative Medicine

Rejuvenation

Theoretical Workshop “Medical Pluralism in Health and Healing�

Prof. K.R. Sethuraman,

Vice-Chancellor, Sri Balaji Vidyapeeth Puducherry “Physico-chemical nurturing of the 'Cell'- A tool for Rejuvenation�

Prof. Samuel Abraham Professor, Yamanashi University Japan

“Research in Integrative medicine: Opportunities & Challenges�

Prof. S.P.Thyagarajan

Pro-Chancellor, Sri Ramachandra Medical University y Chennai “A comparative analysis of modern and traditional medicine�

Prof. M.Prakash Rao

Scientist IV, Central Council For Research In Homeopathy New Delhi

Sanjeevita Motivation Lecture “Rasayana (rejuvenation) in tradition and in recent studies�.

Prof. M.S.Valiathan

National Research Professor, Manipal University Manipal, Karnataka

www.sanjeevita.sbvu.ac.in email to sanjeevita@sbvu.ac.in

Panel Discussion Theme:“Medical pluralism to Integrative Medicine�

Moderator :

Prof. K.R. Sethuraman,

Vice-Chancellor, Sri Balaji Vidyapeeth Puducherry

Panelists :

Prof. P.H. Ananthanarayanan P

Sr. Professor JIPMER, Puducherry

Prof. B.D.Patel

Fmr. Director & Dean, Vinayaka Mission‛s HMC Salem

Prof. Madanmohan Director, CYTER Puducherry

Prof. G.Ganapathy

Fmr. Jt. Director, ISMH and NRHM Chennai

Dr. P.Muralikrishna

Reader, S.V. Ayurvedic College Tirupati

SEPTEMBER 6, 2013 Venue:

MGMCRI, Campus Puducherry

Sri Balaji Educational and Charitable Public Trust

Message from the Chairman

‘Sanjeevita 2013’, the first Annual Summit on the theme ‘Current concepts in Integrative Medicine’, draws attention to the urgent need for research and development to enhance the role of traditional and integrative medicine in health-care delivery. Indian traditional medicine has strong historical and cultural origins. I congratulate the team of Scientists of CIDRF for providing an excellent opportunity, platform for researchers, medical professionals, traditional, conventional health practitioners and communities at large to share information on Integrative medicine. Sanjeevita 2013 sets a vision for collaborative research projects, mobilize resources for generation of knowledge and to impart the importance of traditional & integrative medical treatment. I am confident that Sanjeevita 2013 will yield positive returns in creating scientific temper amongst all the participants and a realization in accepting Integrative medical treatment.

I will continue to support CIDRF in all their endeavours and wish the team of dedicated scientist a successful conduction of ‘Sanjeevita 2013’.

Sri M.K.Rajagopalan.

Chairman

Sri Balaji Educational and Charitable Public Trust

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Sri Balaji Educational and Charitable Public Trust

Message from the Vice Chancellor

“Sanjeevita-2013” is an attempt by the Central for Inter-Disciplinary Research Facility (CIDRF) and Sri Balaji Vidyapeeth (both under the benign support on Sri Balaji Educational & Charitable Public Trust) to foster integrative research in to the art and science of Rejuvenation.

Since ancient times, human beings have been trying to recapture their youth and vitality. Currently there are renowned experts investigating theories and even conducting human trials to evaluate anti aging technologies and solutions. Using genetic mutations and managing nutritional intake, scientists have increased the lifespan of a vast number of species. They have doubled the longevity of the nematode worms, increased the longevity of fruit flies by 85 % and managed to increase the lifespan of mice by 50%.

The normal life expectancy of the initial 8000 generations of humans was 25 years of age or lower. In fact, there has yet to be a discovery of prehistoric human remains older than 50 years of age.

In 1800, the average life expectancy of one born in Sweden was 32 years; by 1900, it had reached the 52 years, and nowadays it has grown up to 82 years — this reflects an amazing 150% increase of lifespan in just two centuries and within the last 8 generations. We still have the power individually to do so much more to improve our odds at an increased life span.

All of us alive today are witnesses to medical advancements and scientific technologies designed to prolong our lives through genetic therapies, cryogenics, stem cell treatments and other cutting edge research. Babies born today would live well into the 22nd Century and be able to play with their great, great, grandchildren.

Sri Balaji Educational and Charitable Public Trust, especially its Chairman Shri MK Rajagopalan, deserve our appreciation for whole heartedly supporting the initiative of “Sanjeevita-2013”.

Professor

SANJEEVITA 2013

K.R. Sethuraman

Vice-Chancellor, SBV.

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Sri Balaji Educational and Charitable Public Trust

Message from the Dean – Research and PG studies

I wish the team of research scientist of Central Inter – Disciplinary Research Facility a great success on their first venture of Annual Summit on ‘Sanjeevita 2013’ ‘Current concepts in Integrative Medicine’ theme Rejuvenation . This summit is surely going to be a trend setter for the present and future generations to get actively involved in research and evidence base in the practice of Integrative Medicine. Wishing the organizing team the very best.

Prof.N.Ananthakrishnan,

Dean – Research and PG studies, SBV

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Sri Balaji Educational and Charitable Public Trust

Message from the Dean – Administration

I am very happy that the Central Inter-Disciplinary Research Facility (CIDRF), Sri Balaji Vidyapeeth and Mahatma Gandhi Medical College and Research Institute are organizing an annual summit on Integrative Medicine and Rejuvenation. Rejuvenation is an important emerging specialty and integrating different systems of medicine is becoming the need of the hour. I wish the summit all success.

SANJEEVITA 2013

Prof.S.Krishnan,

Dean-Admin, MGMCRI

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Sri Balaji Educational and Charitable Public Trust

Message from the Vice-Principal

I am delighted that the Central Inter-Disciplinary Research Facility (CIDRF), Sri Balaji Vidyapeeth and Mahatma Gandhi Medical College and Research Institute are organizing the annual summit titled “ Sanjeevita� with the theme on rejuvenation. The subject is gaining increasing importance given the changing demographic profile of the country. Further, the summit is adopting a novel holistic approach integrating different systems of medicine. I am sure the deliberations between the internationally acclaimed experts will be very useful in the advancement of the science. I wish Sanjeevita 2013 success.

Prof. K. A. Narayan,

Vice-Principal,

MGMCRI

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Sri Balaji Educational and Charitable Public Trust

Message from Advisor (Research) & Director (I/C), CIDRF

Sanjeevita 2013, the first of its kind one day theoretical workshop on the theme ‘Rejuvenation’to be conducted by CIDRF with the active collaboration of Sri Balaji Vidyapeeth should be an eye opener to the people at large and Health care providers in particular to appreciate the concept of Integrative Medicine, in place of prejudices and misgivings about different systems of medicine in the society. The young team under the stewardship of Dr. Balanehru Subramanian, has toiled along with the University team under the leadership of Prof.K.R.Sethuraman,in putting together a program that would place stalwarts and doyens of various systems of medicine on a single platform discussing both the present and future needs in Health Care for all. I am confident that this unique experiment initiated by Sanjeevita 2013, would be carried forward in establishing a’ Centre of Excellence in Rejuvenation’ fulfilling the dream of the organizers. It is gratifying and befitting that on the same day, 17 ‘Research Clusters’ of the Institution to carry forward the worthy suggestions and proposals arising out of the Annual Summit ‘Sanjeevita 2013’ are to be inaugurated by none other than the Founder Chairman SBE&CP Trust and Chancellor of the University ShriM.K.Rajagopalan.

I wish the endeavour and the workshop a grand and historic success.

Prof. G.Subramanian

Advisor (Research) & Director (I/C)

Central Inter – Disciplinary Research Facility Sri Balaji Educational &Charitable Public Trust

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Sri Balaji Educational and Charitable Public Trust

Message from the Deputy Director -CIDRF

A very warm welcome to all of you to the first annual summit, Sanjeevita 2013, organized jointly by CIDRF under the patronage of Sri Balaji Vidyapeeth. The objective of this summit is to bring the scientists and practitioners from different medicinal backgrounds to a single platform where their knowledge is shared and their vision complement each other towards the evolution of healthcare approach towards a healthy and long life. Given the vast knowledge we have gained in modern medicine in last few centuries, combined with the goodness of age old traditional methods of prevention and cure, it is the right time for the amalgamation of the two. While on their own, both modern and traditional health approaches have their strengths and weaknesses, we firmly believe that the union of the two will nullify their individual drawbacks resulting in an Integrative Medicine approach which will have a holistic approach towards the overall well being of human being. We believe that a healthy body is not just disease-free but also possesses a happy and relaxed mind along with a rejuvenated body as a general state of being. This is possible by a holistic lifestyle, healthy diet, physical activity and modern medicinal interventions when required. I am sure that those who have gathered here too believe in our vision for the need of having such a medicinal system. Our Chairman, Sri M.K.Rajagopalan has graciously acknowledged our initiative with a vision to provide integrated healthcare to all and be blessed with long healthy and happy life. Sri Balaji Vidyapeeth has generously provided us the foothold for this endeavor.

Our special thanks to Prof.K.R.Sethuraman, Vice-Chancellor for pivoting this effort from ground zero to this level and further. Of course, our fatherly support 24x7 comes from Prof.G.Subramanian, our Director/Advisor, starting from strategizing of novel ideas to execution. Hearty thanks to these three musketeers for their support. I am hopeful, that using integrative medicine, together we shall be able to attain the goal of health and longevity for a body which is rejuvenated at all the times. Once again, I thank you for your time and support.

Dr. Balanehru Subramanian

Deputy Director Central Inter-Disciplinary Research Facility

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Sri Balaji Educational and Charitable Public Trust

Message from the Organizing Secretary , CIDRF

ALL IS WELL

On behalf of the Organizing Committee, it gives me an immense pleasure and honor to extend invitation for the Annual Summit “Sanjeevita 2013� on Current Concepts in integrative medicine on September 6, 2013 at MGMC&RI campus, Puducherry.

We, the members of Sanjeevita, take the privilege of organizing this summit for the first time of its kind in Puducherry.

A multidisciplinary exchange of information between internationally recognized leading experts, on the challenges facing Integrative Medicine will educate active students, researchers, clinicians and scholars to create a platform for strategic partnership. This summit includes Persuasive speech by Prof.

KR Sethuraman, Thematic Speech by Dr. Samuel JK Abraham, Prof. SP Thyagarajan and Dr. Prakash Rao.

The intriguing Panel Discussion on leveraging strengths of clinical practice in modern medicine to various types of AYUSH healthcare methods will help the participants to understand and acknowledge the existing opportunities in-hand to quench the human quest for better health and longevity.

The key event of the annual summit is the inauguration of 17 research clusters identified from various institutes under SBV patronage. The proposed Center Of Excellence In Rejuvenation (COEIR) will help in integrating translational research into medicine. Collaborations coming through the annual summit could foster research and developments.

The valuable words of eminent National research Professor Dr. MS Valiathan will surely provoke the young minds to step out of reach and claim wonders to make impossible things possible.

Special thanks to Mrs. Asha sureshabu, Mr. Sureshbabu, Mr. Suri, Mr. Kannan, Mr. Prabhakar, Mr. Tamil Selvan and all the hearts who helped Sanjeevita 2013.

We are sure that you will avail this excellent opportunity to enrich your knowledge and make Sanjeevita 2013 memorable and resourceful. We look forward your whole-hearted participation.

We wish you good on behalf of the organizing committee; Welcome you at MGMC&RI campus, Puducherry, India.

Dr. S. Veni

Scientist, CIDRF

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Sri Balaji Educational and Charitable Public Trust

Sanjeevita-2013

Organizing Committee Chief Patron

Shri. M.K.Rajagopalan

Chairman Sri Balaji Educational and Charitable Public Trust Patron

Prof. K.R. Sethuraman Vice-Chancellor Sri Balaji Vidyapeeth

Organizing Chair

Organizing Co-chair

Prof. S. Krishnan Dean-Admin, MGMCRI

Dr. Balanehru Subramanian Deputy Director Central Inter-Disciplinary Research Facility (CIDRF)

Advisory Panel

Prof. N. Ananthakrishnan, Dean-Research and PG studies, Sri Balaji Vidyapeeth Prof. T.R.Gopalan, Dean, SSSMCRI Prof. G. Subramanian, Advisor, (Research) & Director (I/C), CIDRF Prof. K. A. Narayan, Vice-Principal, MGMCRI Prof. Madanmohan, Director, CYTER and Head, Dept. of Physiology,MGMCRI

Org .Secretary

Joint Org. Secretary

Treasurer

Dr. S. Veni Scientist, CIDRF

Dr. Prasant Nayak Assoc Prof. Dept. of Urology, MGMCRI

Dr. D. MubarakAli Scientist CIDRF

Registration

Transport and Logistics

Catering

Scientific Program

Poster Competition

Dr. Pooja Pratheesh Scientist CIDRF

Dr Mahalakshmi.V.N COE, SBV

IT /AV

Dr. Jagan Mohan Asst. Professor Dept. of Pharmacology MGMCRI

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Mrs. Asha Suresh Babu PS to Chairman Mr. S. Karthikeyan CIDRF

Dr. Partha Nandi Assoc. Professor Dept. of Community Medicine MGMCRI

Prof. D.Gunasekaran Dept. of Pediatrics Prof.P.Karthikeyan Head Dept. of ENT

E-Digest

Mrs. A. N. Uma Asst Professor Dept. of Anatomy MGMCRI

Public Relations Mr.Joseph Naresh Deputy Registrar SBV

SANJEEVITA 2013

THE ORGANISING COMMITTEE

Sri Balaji Educational and Charitable Public Trust

SANJEEVITA 2013

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Sri Balaji Educational and Charitable Public Trust

Sanjeevita Theoretical Workshop Session I

CHAIR PERSON : Dr. N. Balaji, MD (Homeo). Govt of Puducherry.

PROFILE : Dr. N. Balaji. MD (HOMEO) Director, ISM&H Directorate of Indian Systems of Medicine & Homoeopathy Govt. of Pondicherry, Pondicherry.

Dr. N. Balaji. did his M.B.S (Homoeo) in Govt.

Homoeopathic Medical college Cuddapah -Andra Pradesh Gold Medalist in MBS from S.V.University, Tirupati. M.D(Homoeo),from Dr.A.M.UniversityAurangabad, Ex: Medical Officer Rotary Service complex Trust, Proddatur. Nodal Officer (Homoeopathy), Govt. Of Puducherry, Best Homoeopathic Practitioner, Award in 1995 by Junior Chamber of CommercePuducherry, Member secretary-High level committee, Mother &child National Program in Homoeopathy of Puducherry, Programme Manager –AYUSH-National Rural Health Mission ,Puducherry, ChairmanSyllabus committee –Diploma Pharmacy courses and Director-Indian Systems of Medicine and Homoeopathy, Govt.Of Puducherry.

MESSAGE FROM GOVT OF PUDUCHERRY Intergrated Medicine: Current Concept

‘Integrated Medicine’ is an approach to care that can be easily incorporated by all Medical Specialties, Professional Disciplines, And By All Health Care Systems Which Addresses The Full Range Of Physical, Emotional, Mental, Social, Spiritual And Environmental Influences That Affect A Person’s Health. The Integrative Approach Emphasizes Prevention, Health Maintenance, Early Intervention, Utilizes All Appropriate, Evidenced-Based and Personalized Therapeutic Approaches To Achieve Optimal Health And Wellbeing In One’s Lifespan.

AYUSH (Ayurveda, Yoga & Naturopathy, Unani, Siddha And Homoeopath), the Major Therapeutic Systems Of Traditional Medicine Play A Major Role In Integrative Medicine. With An Increase Life Style Disorders, There Is A Worldwide Interest In Holistic Systems Of Health Care, Particularly With Respect To The Prevention & Management Of Chronic, Non Communicable And Systemic Diseases. It Is Understood That No Single Health Care System Can Provide Satisfactory Answers To All The Health Needs Of Modem Society. Evidently There Is A Need For A New Inclusive And Integrated Health Care That Should Guide Health Policies And Programmes In Future. Medical Pluralism Is Here To Stay And The AYUSH Sector Has A Pivotal Role To Play In New And Emerging Situation.

Traditional Medicine Is A Revival. Many People Around The World Would Have Healed The Sick With Herbal Or Animal Derived Remedies Handed Down Through Generation. In Africa And Asia, 80% Of Population Still Uses Traditional Medicines Rather Than Modem Medicine For Primary Health Care.

In Developed Nations Traditional Medicine Is Rapidly Gaining Appeal. A Quarter Of Modem Medicines Are Derived From Natural Products. Many Of Which Were First Used In Traditional Medicine.

The Drug Resistance Caused By Misuse Of Medication Has Rendered Several Antibiotics, And Life Saving Drugs Useless, Which Leads To Urgently Looking For Alternative Medicine.

Across The Globe, Researches, Policy Makers, Pharmaceutical Companies And Traditional Healers Are Joining Forces To Bring Integrated Medicine Into 21st Century. The Important Concepts That Make Integrated Medicine Effective In Patient’s Care Are Physicians Should Be Supportive In The Patient’s Care, Health Is Seen As A Vital State Of Physical, Mental, Emotional, Social And Spiritual Wellbeing, The Interventions Are Designed Accordingly. Patients Are Taught How To Recognize, Manage And Decrease The Stress. Nutritional Counseling, Individualized Health Plan Based On The Patient’s Need, Apart From Conventional Interventions. All Other Appropriate Therapeutic Approaches are To Be Followed. All the best “Sanjeevita 2013”.

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Sri Balaji Educational and Charitable Public Trust

Sanjeevita Theoretical Workshop Session II

CHAIRPERSON : Prof. G.Subramanian, Advisor (Research) & Director (I/C), CIDRF Name:

Dr.G.Subramanian, Advisor, (Research) & Director (I/C), CIDRF

Position: Retired from Bharathidasan University, Tiruchirapalli (2003) as: Director, National Facility for Marine Cyanobacteria; Professor & Head Dept. of Microbiology; Co-ordinator School of Life Sciences; Co-ordinator BARD Business Development Centre; Co-ordinator, Bioinformatics Centre.

Presenly: Chairman, Board of Directors, M/S Mykotech Pvt. Ltd., Goa, Member in Research Advisory Committees of DBT; CSIR; & UGC , Govt. of India

Member, Tamil Nadu State Academic Audit & Accreditation Council

Teaching & Research Experience: 47 yrs Publications: Books: 4; Papers : 86; Presentations in Conferences, Seminars Etc. at International & National levels: 97 Research Guidance: Completed M.Phil:14;

Ph.D.: 14; Post doctoral: 12.

Projects completed: Research projects from DOD; DST; ICAR & DBT to a tune of over Rs.7.5 Crores.

International Collaborations: Completed one Indo-US; two Indo-UK and One Indo-Honkong Research projects Countries Visited: USA; UK; France; Japan; Korea: Hongkong; Thailand; Malaysia & Singapore Technologies developed & transferred: Effluent treatment & recycling of Ossein Factory,to M/S.Pioneer MiyagiChemicals(P)Ltd. Cuddalore, Tamil Nadu; Phycocyanin production from marine Cyanobacteria & Antivirals from marine

Cyanobacteria, to M/SABL Biotechnologies, Chennai.

Several technologies for Biofuels; waste treatment, Fine chemicals and drugs in the offing at NFMC. Awards: Won a number of awards & Distinctions from different sources & Member of several learned bodies including editorial boards of Some journals.

Achievements: Established the Microbiology Department of the university; Established the National Facility for Marine Cyanobacteria ; Established the Business Development Centre of the ‘varsity Established the largest Marine Cyanobacterial Germplasm Collection in the world.

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Sanjeevita Theoretical Workshop Session I

Persuasive Speech “Holistic Healing and Medical Pluralism” Prof. K. R. Sethuraman, Vice-Chancellor, Sri Balaji Vidyapeeth PROFILE

Dr K.R. Sethuraman, joined as the Vice Chancellor Sri Balaji Vidyapeeth on 05.04.2013.

He has completed his undergraduate (1966-72) and postgraduate (1973-76) Medical Education in Internal Medicine at JIPMER, Pondicherry. Later, he underwent training in Cardiology at SCTIMST at Thiruvananthapuram for three years, from 1978 to ‘81. He joined JIPMER as a Lecturer in Medicine and served there for 25 years (1981-2006). He was promoted as a Professor of Medicine in 1991, as the head of department of Medical Education in 2000 and as the Director-Professor and Head of Medicine in 2003.

He took voluntary retirement in 2006 and moved over to Malaysia as the Dean of Medicine at AIMST University (www.aimst.edu.my) for 7 years. During this period, he was also the Deputy ViceChancellor of Academic and International Affairs from 2008. The medical programme at AIMST was consolidated during his tenure and more than 80% of the graduates were found to be fully competent.

His interests are varied and wide. He is an eminent educationist and has over four decades of experience in medical education.

Prof. K.R.Sethuraman is a meticulous and a prolific writer, and has published books/monographs on Rational Therapy, Medical Education, Doctor-Patient Communication, Clinical Echography, Objective Structured Clinical Examination and Medical Ethics & Professionalism. The last one, translated in Tamil (titled “Post Mortem”) has sold more than 10,000 copies. He has produced videos for teaching purposes on medical promotion, oral communication skills and on “how to face an oral examination”.

Since 2005, he is a member of the International Advisory Panel for three editions of Davidson’s Textbook of Medicine, and has contributed chapters for the companion volumes - Davidson’s Clinical Cases & Davidson’s 100 Clinical Cases. He is all set for the next edition of “Davidson’s Principles and Practice of Medicine” expected to be released in late 2014. He is a strong believer of scientific research and harnesses curiosity in the minds of young medical students, creating a wave of scientific temper in them. He has to his credit over 40 indexed publications He has visited South Africa, Sri Lanka, Thailand and New Delhi as short term advisor to WHO.

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ABSTRACT 1

Sri Balaji Educational and Charitable Public Trust

“Holistic Healing and Medical Pluralism” Prof. K. R. Sethuraman, Vice-Chancellor, Sri Balaji Vidyapeeth

Holistic healing is rarely discussed in “Western Medicine” unlike other disciplines like Medical Sociology, Medical Anthropology and traditional systems of Medicine (AYUSH disciplines). Holistic Healing is “ to achieve or acquire wholeness as a person. The wholeness involves physical, emotional, intellectual, social, and spiritual aspects of human experience.” (TR Egnew. MD)

The types of Healing include, Spontaneous (natural) healing, Technological healing (based on active medications or procedures) and Interpersonal (faith-based) healing. Wickenburg Consensus in 1988 has estimated that rational therapy accounted for only 20% of healing process; the remainder comes from Placebo effect, Hawthorne effect and Spiritual factor.

I. Placebo & Nocebo effects are two sides of a coin. Placebo is “I shall please” in Latin. Nocebo is “I shall harm” in Latin. Placebo response rate is from 15% to 58% with a mean of 35% (Prof Beecher of Harvard in 1955). Prof HM Spiro of Yale (1986) has said, “In clinical trials of duodenal ulcer, the placebo benefit was up to 70% and a mean of 50%”. Ted Kaptchuk (1998) a Harvard Professor says, “It is undoubtedly time that the powerful placebo be examined in all its myriad facets; otherwise medicine will always have a limited perception of healing.” Post Modern Voices say, “Patients could benefit from clinicians maximising the potential of placebo effects associated with effective therapies.” (Ernst, 2007)

II. Hawthorne effect: (‘caring’ as a beneficial force) A classic Harvard study in Western Electric’s factory at Hawthorne during 1927–37 proved that when employees perceived that the employer “cared”, productivity always improved. Hawthorne effect is relevant to all “caring” enterprises including health care. Patients “feel better” after deciding to put themselves under the care of a physician, a nurse, or a hospital. The attitudes of the management and supervisors influenced the length of hospital stay: the more supportive the management, the shorter the hospital stay. “Unfortunately, the healthcare providers and managers have, until recently, ignored these seminal ideas” (Dr Kerr White, 1996).

III. Spiritual factor and Health: The WHO definition of health was revised in 1984 by SEARO: “Health is a dynamic state of complete physical, mental, spiritual and social well-being.” (Khayat, 1998).

A WHO study on Quality of Life, Spirituality, Religion & Personal Beliefs (SRPB) involved 5087 subjects in 18 countries. SRPB factors correlated with all the Quality of Life domains. Women reported greater feelings of spiritual connection and faith than men. Less educated reported greater faith but was less hopeful. We need to assess our patients’ Spirituality, Religion & Personal Beliefs as they affect the perceived quality of life

Association of American Medical Colleges adopted Spirituality in 1999 and announced, “Spirituality is an individual’s search for the ultimate meaning through participation in religion and/ or belief in God, family, naturalism, rationalism, humanism, and the arts. These factors influence how patients and health care professionals perceive health & illness and how they interact with one another.”

Post Modern Views on Spirituality: Prayer is not a substitute for rational medical treatment but it is an important element in the way patients cope with chronic illness, suffering, and loss. Physicians need to address and be attentive to all suffering of their patients – be it physical, emotional, or spiritual.

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Sri Balaji Educational and Charitable Public Trust

Thematic Speech I “Physico-chemical nurturing of the ‘Cell’- A tool for Rejuvenation” Dr. Samuel Abraham, Professor, Yamanashi University, Japan PROFILE • Completed primary medical degree in Tirunelveli Medical College in 1992, India. After a year in Pediatric surgery training, joined Yamanashi Medical University, Japan in 1993. Finished post-graduate training in Cardiac surgery in 1999 and got PhD. Since then with the Division of Pediatric Cardiac Surgery, Yamanashi University-Faculty of Medicine, Japan till date.

• Visiting professor, The Tamilnadu Dr MGR Medical University, Chennai, India • Started research in stem cells beside clinical cardiac surgery work with institutes in Japan under the Nichi-In consortium, Tokyo, Japan in 2000 • Established the Nichi-In Centre for Regenerative Medicine (NCRM.org) in India (2005) and centers overseas through technological collaboration; Niscell (2008) & Visiontec (2009; visiontecinc.com) in Malaysia.

• Distinguished Visiting Professor Award by the University of Toronto, CIHR TPRM April 2012.

• Adjunct Faculty, INDICASAT, Panama, April 2012 List of publications available at: http://www.ncrm.org/feat/pub/index.htm Interests 1. Translation of bench-side technologies for in vitro cell culture and tissue engineering using nanomaterials and polymers to the bed-side 2. Studying the complexity of physico-chemical-biological interactions by way of reproducing in vitro biomimicking systems with nanomaterials and environments 3. Immortalization and arrest of the process of aging of cells by subjecting them to various physicochemical-biological environments and influences including zero-gravity of the outer space 4. Development and evolution of immune system through the ladder of phylogeny Projects • Areas of research in regenerative medicine include: (i) Corneal limbal stem cells, endothelial progenitors, (cesbank.org) (ii) Hybrid Artificial Corneal Prosthesis (hybridcornea.org) (iii) Hepatic progenitors for drug toxicology screening, (iv) Natural killer cell based immunotherapy for cancer & viral infections, (www.aietforcancer.org) (v) Human monoclonal antibodies for cancer, (vi) Cell based therapies for anti-aging, (vii) In vitro expansion of human hematopoietic stem cells, (viii) Tissue engineering of human chondrocytes, (ix) Nanomaterial based scaffolds for cell culture and tissue engineering, (x) Dental stem cells.

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ABSTRACT 2

Sri Balaji Educational and Charitable Public Trust

Physico-chemical nurturing of the ‘Cell’- A tool for Rejuvenation Dr. Samuel JK Abraham, Nichi-In Centre for Regenerative Medicine (NCRM), India & Yamanashi University Hospital, Japan

The microenvironment within the body where stem cells reside and are nurtured (the stem cell niche) in various organs including that of Hematopoietic stem cells (HSCs) in the bone marrow (BM) has always been a challenge when it comes to understanding their intricacies. But, as we travel back in time to that of unicellular organisms in evolution, the nature per se was the niche for those unicellular organisms, where they were in direct contact with naturally occurring substances like rocks, soil, water etc. In the process of evolution, as unicellular organisms evolved to become multicellular, the term niche became a separate entity, internally specific to each organ within that organism (1). Cells in the unicellular organisms were directly exposed to physical and chemical influences of the nature and after developing into multicellular organisms with specific organs, the influence of physico-chemical factors became indirect. Nevertheless, physical forces and chemical moieties do play a role either directly or indirectly in every organism and their internal niche.

In vitro cell or tissue culture in the earliest recorded history was done using simple chemical solutions, mainly balanced salt solutions (2) which were later modified to include biological components as well (3,4). In recent times as more evidences have started gathering, chemically defined synthetic media is used for the cell culture (5) and the influence of physical forces on the cell culture has also started becoming more evident (6). Our experience till date proves that chemically synthesised polymers and nanomaterial based scaffolds could allow an in vitro expansion of the cells such as corneal limbal stem cells (7), corneal endothelial precursors (8) and chondrocytes (9) in the laboratory, which not only avoids potential threat of biological material based contamination but also ensures reproducibility as well as simplicity.

The process of rejuvenation using in vitro expanded cells has been our major area of interest, having been equipped with contamination free, easily reproducible cell culture methodologies of different types of cells. While in vitro expanded autologous fibroblast replenishment (10) has been able to bring back a youthful facial skin, cellular senescence under various physical and chemical environments is an important area for future research. In vitro expansion of immune cells such as Natural Killer (NK) cells and T cells without animal derived feeder layers is a proven procedure for treating cancer (11) and studies have been reported wherein such immune cells could bring down the viral load (12). The hematopoietic stem cells with known age related damages when could be cultured in vitro and be cryopreserved without the damages that are inflicted during the process of aging in vivo, may open new avenues for total rejuvenation of the human body.

References:

http://www.metaniche.org/ Miller DJ. J Physiol. 2004; 555:585-7 Harrison R. Anat Rec. 1907 1:116-128.

Harrison R. J Exp Zool. 1910; 9:787-846.

Ham RG. Proc Natl Acad Sci U S A. 1965; 53:288-93.

Engler AJ et al. Cell. 2006;126:677-89.

Sitalakshmi G et al. Tissue Eng Part A. 2009;15:407-15.

Rao S et al. Indian Journal of Ophthalmology (In print) Arumugam S et al. J.Orthopaedics 2011; 8(3)e5. http://www.miawmi.com/ Takada M et al. Breast Cancer. 2011;18:64-7.

Zhang T et al. Antiviral Res. 2007;73:132-9.

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Sanjeevita Theoretical Workshop Session II

Thematic Speech II “Research in Integrative medicine : Opportunities & Challenges” Prof. S. P. Thyagarajan, Pro Chancellor (Research), Sri Ramachandra Medical University, Chennai PROFILE:

Prof. S.P. Thyagarajan, is a D.Sc., in Microbiology in addition to his Ph.D. and M.D. Degrees. He has also been conferred with several Fellowship titles including those by National Academy of Sciences and National Academy of Medical Sciences. He has put in 40 years of UG/PG teaching and research experience in Tamilnadu Medical Colleges and in University of Madras. He has till date completed 57 research projects funded by national and inter-national funding agencies and mobilized research grants over Rs.35.0 crore to the University of Madras. He has published 320 research papers and 16 books in the area of infectious diseases especially hepatitis, STDs and HIV/ AIDS. He is member of expert committees of UGC, ICMR, DST.,DBT, DOD, Ministry of Health, WHO etc.Prof. Thyagarajan is the inventor of a drug for the treatment of Chronic jaundice, called Hepatitis-B from the Indian medicinal plant, Phyllanthus amarus, [Kizhanelli in Tamil]. He has also secured national/ international patent for this discovery on the name of University of Madras and the patents have already been awarded in USA, UK, South Africa and North Korea. The drug has already been marketed by an University-Industry agreement under the brand name “VIROHEP” by Rallis India Pharmaceuticals/ Shreya Life Sciences, Mumbai, bringing financial benefits to the University. He additionally holds three more Indian patents.

He has been involved in HIV/AIDs research from the time HIV positivity was first reported in India at Madras Medical college through ICMR/Indo-Uk and INDO-US projects.

Prof. Thyagarajan , as the Vice-Chancellor of the University of Madras between 2003-2006, besides bringing laurels to the University through “University with Potentials of Excellence” and other schemes, spear- headed the 150th year celebrations of the University by securing a special grant of Rs.125 crores from Govt.of India and conducted the 150th Year celebrations on 4-5, Sept,2006 inaugurated by His Excellency, Dr.A. P. J. Abdul Kalam, Former President of India along with His Excellency Governor of Tamilnadu, Honourable Chief Minister of Tamilnadu and other VVIPS from Central Govt and State Govt. He has served the National Assessment and Accreditation Council (INDIA) since 1999 as NAAC Peer Team Member/Chairman for about 30 colleges and 10 Universities in the country. He is presently nominated by Government of Tamilnadu as Chairman, Tamilnadu State Academic Audit and Accreditation Council (TNSAAC). As a recognized Higher Education expert of the country, he has been heading several MHRD/UGC Expert Committees of X and XI Plan Schemes. He has facilitated NAAC accreditation of Sri Ramachandra University at “A” Grade level and MOUs with 16 foreign Universities besides 34 Indian Universities, institutions and industries.

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ABSTRACT 3

Sri Balaji Educational and Charitable Public Trust

Thematic Speech II “Research in Integrative medicine: Opportunities & Challenges” Prof. S. P. Thyagarajan, Pro Chancellor (Research), Sri Ramachandra Medical University, Chennai

Integrative Medicine (IM) refers to a healthcare system that is prospective and holistic, while patient centered and personalized at the same time, focusing on health and wellbeing of the people in addition to disease management. It is not to be equated with Complementary and Alternative Medicine (CAM) or the spectrum of Traditional Systems of Medicine. Integrative medicine researchers have broadly adopted the paradigm of evidence based medicine (EBM) which includes randomized controlled clinical trials (RCT).

Conducting IM research continues to be challenging for the IM researchers (i) in areas of evaluating IM using existing models of scientific research, (ii) difficulty in obtaining the required proportion of grants for in-depth studies, (iii) to find internationally acclaimed journals to accept IM research outputs and (iv) the legal challenges in the practice of IM in medical institutions and hospitals.

Despite all of these challenges, there have been many research teams at major universities in the world, who have made significant inroads into delineating the science of IM using traditional RCT study designs. For example, Taichi’s effectiveness in treating headache; “Whole Systems Research (WSR)” in Ayurveda or Chinese medicine and “Health Services Research (HSR)” to demonstrate the validity of alternative forms of research in CAM/IM.

A similar attempt successfully made by our group for a period spanning over 25 years to validate the use of a medicinal plant, Phyllanthus amarus-based drug for the treatment of chronic carriers of Hepatitis B which finally received patents and international acclaim would be included in the presentation.

Thus, in order to systematize successful conduct of research in Integrative Medicine, the following strategies would be of great value:

1.Identify the prime areas of research in integrative medicine and define the level of evidence required for their clinical applications.

2.Establish a consortium of integrative medicine researchers to form consensus on how to implement the research priorities.

3.Build an international information technology platform which standardizes and facilitates data acquisition, data banking, and communication between researchers to achieve synergy of productivity.

4.Demonstrate the value of integrative medicine in health maintenance and disease prevention to policy making bodies including legal bodies, especially in light of the current economic setting of burdoning health care cost to society, so that more resources can be allocated to integrative medicine research.

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Thematic Speech III “A comparative analysis of modern and traditional medicine” Prof. M. Prakash Rao, Scientist IV, Central Council for Research in Homeopathy, New Delhi PROFILE Dr.M.Prakash Rao , Scientist-4 ,Assistant Director (H) , Clinical Research Unit for Homoeopathy (T) Puducherry , (Under Central Council for Research in Homoeopathy AYUSH Department Got of India). Did D.H.M.S at J.S.P.S. Homoeopathic Medical College, Hyderabad. (A.P.). B.A.(English, Sociology) at Osmania University Hyderabad.(A.P), PG Diploma in Medical Rehabilitation at All India Institute of Physical Medicine and Rehabilitation, (Govt. of India) Bombay and M.D (Homoeopathy) at Agra University.

Clinical Research on : Bronchial Asthma, Filariasis, Diabetes Mellitus, Osteoarthritis, Peptic Ulcer, Respiratory Infections, Menopausal Symptoms, Chronic Bronchitis, Cervical Spondylosis, Efficacy of Homoeopathy medicines in Pre Diabetic Condition, Diabetic Distal Neuropathy, Hyper lipidemia.

Door to door survey and Incidental Medical aid in the state of Puducherry.

Collaborative studies with JIPMER Drugs used in Insomnia on serum melatonin and Cortisol levels in Healthy volunteers Extra mural Research JIPMER Under taking Research, work on Immunological studies in Rheumatoid Arthritis treated with Homoeopathic drugs, as Extra mural project.

Extra mural Research JIPMER Modulation of cytokine profile on exposure to Homeopathic drugs in Rheumatoid Arthritis in vitro lymphoproliferation studies Publications : 23 Project works : Under taken Project work Sponsored by UNICEF and worked as Research Advisory Committee member in Collaboration with Department of Economics Pondicherry Central University and Completed the Project Work on “An Analysis of the Situation of Children in Pondicherry “ from November 1988 to November 1989

Awards : Received “Outstanding Young Person Award” from Junior Chamber of Pondicherry in the year 1990., Received “Certificate Appreciation from Lieutenant Governor of Pondicherry for effectively treating various patients, Received “Vocational Excellence Award” in 1999 from Rotary Club of Pondicherry Mid Town., Received “Outstanding Services to People Award” by Lions Club of Pondicherry in December 1994., Received “Award for Organising Various Health Camps” by Bharath Jan Vigyan Jatha in the year 1994., Received “Citation for popularizing Homoeopathy in Pondicherry and Tamil Nadu” by Tamil Nadu Homoeopathic Qualified Doctors Association in 1996., Received various certificates of Appreciation, Mementoes, and Citations for extending free Homoeopathic Treatment from last 20 years.

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ABSTRACT: Thematic Speech III: “A comparative analysis of modern and traditional medicine” Prof. M. Prakash Rao, Scientist IV, Central Council for Research in Homeopathy, New Delhi

The term “traditional medicine” (TM) refers to ways of protecting and restoring health that existed before the arrival of modern medicine. As the term implies, these approaches to health belong to the traditions of each country, and have been handed down from generation to generation. Traditional medicines (TM) have met needs of the local communities for centuries. Now the terms such as alternative medicine complimentary medicine are used interchangeably to refer the traditional medicine all over the world. Despite derived from diverse cultures, Languages, Geographical locations and health beliefs of people all over the world , the common specialty and peculiarity that unites all types of alternate systems is “Holistic approach” In 21st millennium, medical science has developed in a rapid manner particularly in the field of evidence based research. At the same time a genuine interest in various traditional practices subsists among practitioners of modern medicine along with the growing numbers of practitioners of traditional systems, acquainted with the modern technology. This kind of integration facilitates and fosters teamwork among all categories of medical professional to cater the requirements in primary health and promotes research in diverse facets for nerve-racking medical problems.

In developing countries including India, the work force represented by practitioners of traditional medicine is a potentially important resource for the delivery of health care. The World Health organization (WHO) supported every effort to formulate national policies, potential usefulness of traditional medicine as well as to evaluate the safety and efficacy of remedies to study and upgrade the knowledge of traditional medicines among modern health practitioners.

Traditional medicines, despite their limitations, are addressing health needs of millions of people worldwide. It is estimated that about 65-85% of the world population uses traditional medicines for their primary health care. It is also estimated that about 39% of all 520 newly approved drugs in 1983-1994 were natural products and out of that 74% were discovered as a result of bio-prospecting from plants used in traditional medicines. Traditional medicines are increasingly getting more popular mainly because (a) it is holistic system with fewer side effects (b) it is evolving as an evidence-based medicine and (c) its ethno-medical knowledge is applicable to modern drug discovery programs. It is found that there are many diseases that cannot be cured by the existing drugs and the incidence of drug resistance is increasing, consequently there is urgent need for drugs that are effective against these pathogens. Probably, traditional medicines can provide a solution in fighting them as a health care delivery mechanism as well as in exploring the medical research. As the emergence and resurgence of Traditional medicines (TM) in health care is evident worldwide. This paper attempts to make a comparative analysis to find out the current state of traditional medicine in India with respect to infrastructure development such as educational institutes, organizations, practices and therapeutic scope attitude towards alternate medicine with its limitation and implications in the field of health and medicine.

Keywords: World health organization (WHO), Traditional medicine (TM), Complimentary medicine (CAM) Holistic System,

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Center Of Excellence in Rejuvenation RESEARCH CLUSTER 1: Integrative Medicine in Lifestyle diseases Leader: Dr. Palanivelu, Pulmonary Medicine Members: Dr. Partha Nandi, Community Medicine. Dr. Henri Balraj K, Physiology.

Dr. Mahendra B.Gandhe, Biochemistry.

Mrs. A.N Uma, Anatomy RESEARCH CLUSTER 2: Antiaging and Skin care Leader: Dr. Krishnan S, DVL. Members: Dr. Yuti Chinmay Nakhwa, DVL Dr. Manimekalai K, Pharmacology Dr. Padmavathi S, Pharmacology Dr Saha,S., Biochemistry RESEARCH CLUSTER 3: Geriatric/Gerontology Care-based Projects Leader: Dr. Ganesh Babu C P, Surgery Members: Dr. Tirou Aroul T, Surgery Dr. Kannan R, General Surgery Dr. Seetharaman N, Community Medicine Dr. Seetesh Ghose, OB&GY Dr. Partha Nandi, Community Medicine Dr. Prasant Nayak, Urology

Members:Dr. Jai Ganesh K, Physiology Dr. Sobana R, Physiology Dr. Mangala Gowri S R, Physiology Dr. Satvinder Singh Bakshi, ENT Dr. Rajkumar Patil, Community Medicine RESEARCH CLUSTER 8: Cell-based Therapies Leader: Dr. Henri Balraj K, Physiology Members:Dr. Satvinder Singh Bakshi, ENT Dr. Mangala G, Pathology Dr. Vaishali Kotasthane, Pathology Dr. Prasant Nayak, Urology Dr. Kannan R, General Surgery Dr. Ganesh Babu C P, General Surgery Dr. Rathan Shetty, ENT RESEARCH CLUSTER 9: Mother and Child care Leader: Dr. Seethesh Ghose, OB&GY Members:ALL OB&GY, Pediatrics Dr. Srinivasan S, Pediatrics Dr. Mahalakshmi V N, Paediatric Surgery Dr. Partha Nandi, Community Medicine Mrs. A.N Uma, Anatomy

RESEARCH CLUSTER 4: Relaxation, Group counseling, Education & Rehabilitation Leader: Dr. Sukanto Sarkar, Psychiatry Members: Dr. Narayan K.A, Community Medicine Dr. Seetharannan N, Community Medicine Dr. Ravishankar M, Anesthesiology Dr. Kannan R, General Surgery

RESEARCH CLUSTER 10: Mental Health Leader: Dr. Eswaran S, Psychiatry Members:Dr. Sukanto Sarkar, Psychiatry Dr. Anandraj R, OBGY Dr. Henri Balraj K, Physiology Dr. Kingshuk Lahon, Pharmacology Dr. Vaithiyanathan P, Community Medicine

RESEARCH CLUSTER 5: Allergy Management Leader: Dr. Srinivasan S, Paediatrics Members:Dr. Venkatesh C, Paediatrics.

Dr. Gunasekaran D, Paediatrics Dr. Pajanivel R, Pulmonary Medicine Dr. Karthikeyan P, ENT Dr. Satvinder Singh Bakshi, ENT Dr. Rathan Shetty K S, ENT Dr. Sathish Babu, Biochemistry Dr. Krishnan S, DVL Dr. Ravishankar M, Anesthesiology

RESEARCH CLUSTER 11: Rejuvenation Therapies Leader: Dr. Pallavee P, OB&GY Members:Dr. Sunita Samal, OB&GY Dr. Shweta, OB&GY Dr. Anandraj, OB&GY Dr. Ravishankar M, Anesthesiology Dr. Mahalakshmi V N, Paediatric Surgery Dr. Sentitoshi, Forensic Medicine Dr. Somasundaram.G, Pharmacology

RESEARCH CLUSTER 6: Personalized Healthcare Database Leader: Dr. Narayan K.A., Comm. Medicine Members:Dr. Amirtha Ganesh B, Cardiology Dr. Mahalakshmi V N, Pediatric Surgery Dr. Jagan Mohan R, Pharmacology RESEARCH CLUSTER 7: Lifestyle-based Projects Leader: Dr. Madan Mohan, Physiology 22

RESEARCH CLUSTER 12: Pharmacovigilence and Biomarkers Leader: Dr. Kingshuk Lahon, Pharmacology Members: Dr. Padmavathi S, Pharmacology Dr. Mangala G, Pathology Dr. Satvinder Singh Bakshi, ENT Dr. Rathan Shetty K S, ENT Dr. Henri Balraj, Physiology Mrs. A.N Uma, Anatomy

SANJEEVITA 2013

COEIR - MGMCRI MEMBERS OF THE RESEARCH CLUSTERS

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RESEARCH CLUSTER 1

Integrative Medicine in Lifestyle diseases

Cluster Vision

To establish practice - based interdisciplinary research to collect, validate, and disseminate research in lifestyle diseases, systems, and integrative medicine.

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RESEARCH CLUSTER 2

Sri Balaji Educational and Charitable Public Trust

Antiaging and Skin care

Cluster Vision

To promote healthy skin by preventing premature aging, photodamage, photoaging and skin damage from oxidative stress.

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RESEARCH CLUSTER 3

Geriatric/Gerontology Care-based Projects

Cluster Vision

To integrate, promote and provide rejuvenation for geriatric age.

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RESEARCH CLUSTER 4

Sri Balaji Educational and Charitable Public Trust

Relaxation, Group counseling, Education & Rehabilitation

Cluster Vision

To have a positive influence on individuals and communities by promoting wellness through counseling and relaxation.

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RESEARCH CLUSTER 5

Allergy Management

Cluster Vision

To integrate beneficial effects of yoga, ayurveda, diet manipulation and music therapy towards the treatment of asthma and allergy.

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RESEARCH CLUSTER 6

Sri Balaji Educational and Charitable Public Trust

Personalized Healthcare Database

Cluster Vision

To promote a knowledge society for integrative medicine and rejuvination by establishing a collaborative platform and a knowledge repository.

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RESEARCH CLUSTER 7

Lifestyle-based Projects

Cluster Vision

To integrate yoga and modern medicine for better health care delivery of tomorrow

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RESEARCH CLUSTER 8

Sri Balaji Educational and Charitable Public Trust

Cell-based Therapies

Cluster Vision

To heal injured cell, curb tissue inflammation, generate support tissue and tackle neoplasm.

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RESEARCH CLUSTER 9

Mother and Child care

Cluster Vision

To alleviate the suffering of the labouring mother and improving the cognitive function of the child.

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RESEARCH CLUSTER 10

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Mental Health

Cluster Vision

To identify, detect and improve indicators of mental health through integrative approaches.

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RESEARCH CLUSTER 11

Rejuvenation Therapies

Cluster Vision

To promote and progress towards identification of means to rejuvenate mind, body and spirit at physiological and molecular level.

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RESEARCH CLUSTER 12

Sri Balaji Educational and Charitable Public Trust

Pharmacovigilence and Biomarkers

Cluster Vision

To assess the safety of traditional medicines,build evidence base for their effective use and discover new biomarkers for diagnostic and prognostic purposes.

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Cell Based Therapy

Personalized Oral Healthcare Database

Dental Bio Materials

II

III

IV

V

- Reader

- OMR

To integrate the alternate medicines and to formulate Dr. Manoharan. P.S new dental biomaterials for Prof & H.O.D the repair & regeneration of Prosthodontics dental hard & soft issue.

Dr. David Livingstone -Reader

-Professor

Dr. Srinivasan. J

- Prostho

- Prostho

-Prof & H.O.D - Pedo

Dr. Arun Silas Jacob

Dr. Sathyanarayanan. R -Prof & H.O.D - ODS

Dr. Santhadevy. A -Professor- O.Path To modify, regulate,& Dr. Viswanath Rangdhol Dr. Vezavendhan. N -Reader - O.Path rejuvenate the dento alveolar Prof & H.O.D cells at the molecular level Dr. Pratheeba. B -Reader - Perio through integrated medicine. Oral Medicine Dr. Manikandan. R -Reader - ODS Dr. Carounanidy Usha - Professor - ODS To accumulate evidence, Dr. Senthil. M Dr. Kuldeep Singh - Sr. Lecturer - PHD at the community level, Reader about impact of traditional Dr. Anitha - Sr. Lecturer - Perio medicine in Oral health care Public Health Dentistry Dr. Sanguida. A - Sr. Lecture - Pedo

Dr. Hanumanth. S-Sr. Lecturer - Ortho

Dr. Jayaraj. D - Sr. Lecturer - Pedo

Dr. Jeelani. S

Dr. Ramesh. C - Prof & H.O.D - Oral Surgery

Pain, Anxiety and Stress Management

A

To develop alternate strategies with traditional Dr. Nandakumar. treatments to minimize & Prof & H.O.D eradicate the pain, anxiety & stress associated with dental Orthodontics services.

Life style based Oral diseases

Members

I

Leader

To integrate the traditional Dr. Saravanakumar . R - Prof & H.O.D- Perio. medicinal therapies in the prevention and management Dr. Kayalvizhi. B - Reader - Pedo of life-style bared oral Dr.Sathyanarayanan. R - Reader - OMR diseases such as Dental Prof & Head Cons & Dr. Dany. A Caries, Periodontal diseases Endo.

Dr. Janani. M - Sr. Lecturer - Perio & Oral cancer.

Vision

Name

Cluster

IGIDS - Research Clusters And Themes

Center Of Excellence in Rejuvenation

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COEIR - IGIDS MEMBERS OF THE RESEARCH CLUSTERS

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Sanjeevita Panel Discussion

Panel Discussion Theme “Medical pluralism to Integrative Medicine” Moderator: Prof. K. R. Sethuraman, Vice Chancellor, Sri Balaji Vidyapeeth Panelists

Prof. P.H.Ananthanarayanan Director – Professor & Head Dept. of Biochemistry, JIPMER, Puducherry Prof. B.D.Patel Fmr. Director and Dean, Vinayaka Mission’s Homoepathy Medical College, Bangalore Prof. Madan Mohan, Director, Center for Yoga Therapy, Education and Research, Puducherry Prof. G.Ganapathy Fmr. Jt. Director, Indian System of Medicine and Homeopathy (ISMH), Chennai Dr. P. Muralikrishna Reader, S.V.Ayurvedic College, Tirupati.

PROFILE Dr. P.H. Ananthanarayanan Sr.Professor, JIPMER, Puducherry Email Id :- phananthanarayanan@gmail.com MD (Biochemistry), 1977, (University of Madras), Currently Professor, Department of Biochemistry and Faculty (Admin), JIPMER, Puducherry, Formerly, Deputy Director General (ME), Directorate General of Health Services, New Delhi; Director, All India Institute of Hygiene and Public Health, Kolkata; Director, JIPMER, Pondicherry

Founder Professor and Head, Department of Biochemistry, B. P. Koirala Institute of Health Sciences, Dharan, Nepal (on deputation by the Government of India). Association of Clinical Biochemists of India – Life Member

Held offices of: Fellow of Indian Public Health Association; Member of the Advisory Committee, ICMR, New Delhi; Member of the Project Advisory Committee, B P Koirala Institute of Health Sciences, Dharan, Nepal;

Chairperson of the Election Committee of the Indian Public Health Association since 2002; Member of the Governing Body of Chittaranjan National Cancer Institute, Kolkata; Member of the Board of Governors of Indian Institute of Social Welfare and Business Management, Kolkata; Member of the Research Advisory Committee for the Ministry of Environment and Forests, Government of India since 2003; Member of the Governing Body of Indian Association of Social Sciences; and various other portfolios. Member of the Board of Studies in Undergraduate and Post Graduate Medicine of Pondicherry, Goa Universities, NTR University of Health Sciences, Andhra Pradesh since1984 to 1999.

Active Member of the Scientific Council of Heinz Nutrition Foundation of India since 1999. Examiner and Question Paper Setter for various Undergraduate and Post graduate Courses in Biochemistry.

Examiner for the National Board of Examinations, Government of India from 1979 till date.

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Disscussion Preview 1 1.

The areas of strength of the Allopathic system of Healthcare:

A thorough system of history taking, proper examination of the patient, investigations and treatment and monitoring of the patient with proper nutrition and advice on health promotion and education: a constant system of updating the knowledge base and proper training in acquiring the necessary skills make the system strong and robust.

2.

The areas in which you could use expertise from other systems of healthcare to benefit your patients/clients:

The National Health Policy of our country spells out clearly an interdisciplinary approach and integration of modern system of medicine with other systems of health care like, Ayurveda, Yoga, Unani, Siddha and Homeopathy (AYUSH). The best practices of health care delivery in other such systems can be integrated into modern system of medicine wherever feasible and make the total healthcare delivery system strong, active and beneficial to the population. Several examples are available in this regard.

3.

What are the opportunities for integrated collaborative healthcare in your wish list?

Opportunities are infinite. Lifestyle diseases are the classic example where integrated collaborative healthcare delivery is practiced.The beneficial effects of physical activity, yoga, breathing exercises, proper food and nutritionand asanas are well documented and accepted as a way of management of lifestyle diseases. Oncology is another branch where integrated approach is found to be benefitting the patients.

The wish list is enormous.

4.

What are the challenges you foresee in making your wish list a reality?

Mindset needs to be changed. Allopathic medicine is not the panacea for all illnesses. It has its own limitations. We need to wear proper spectacles to have proper vision and similarly, be ready to accept the good things from other systems of healthcare practices. It is not a good practice to belittle other systems of medicine without detailed knowledge of them. No system is perfect but there are systems which are nearer to perfection. If we have a receptive attitude, these wish lists will be a reality.

These points will be discussed in detail during the panel discussion.

PROFILE: Prof. B.D.Patel Former Director & Dean, V.M.Homoeo Medical College, Salem , Former.Principal, Govt. Homoeo Medical College, Bangalore &Chandigarh(U.T),Former.

Chairman Board Of Studies (homoeo) Bang.University.

Prof. B.D.Patel did his BSc. M.D.(Homoeo) PGRT (BOM), Former Director & Dean, V.M.Homoeo Medical College, Salem , Former.Principal, Govt. Homoeo Medical College, Bangalore &Chandigarh(U.T),Former. Chairman Board Of Studies (homoeo) Bang.University. Former.Member: Advisory Committee (Homoeo), Government Of Karnataka, Expert Committee, (Homoeopathy) and Member Karnatka Public Service Commission..Member: Bharat Vikas Parishad, Rotary, many Medical & Social Organisations. Languages Known: Hindi,Urdu,Bhojpuri,kannada, Telugu, Marathi, Gujarati, Tamil, Punjabi, Bangla, English, Malayalam, Sanskrit. Awards : Excellence Service In Homoeopathy By Research Society Of India, Dr. Hahnemann memorial national award.Conducted no. of Inter National Homoeopathic Conferences. T.V. & Radio interviews in India & European countries. Published many articles appearing in leading Magazines of India and Europe.Widely traveled. Youth Trainer, Conducts Special Programmes for youth. Conducted workshop on Vedas in Croatia SANJEEVITA 2013

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Sri Balaji Educational and Charitable Public Trust Disscussion Preview 2

Homoeopathy – utilise to its fullest potential

Homeopathy is a natural pharmaceutical science that utilizes extremely small doses of substances to stimulate a person’s immune and defence systems. It considers the mind and body are inter-dependent in Health – Disease – Cure Basically it is individualistic medical system rather than generalised – hence there are no specific Medicines for specific Diseases.

Each medicine is individually prescribed according to the “Law of Similars” that is, a substance which is capable of evoking a certain set of symptoms in an essentially healthy person under controlled research procedures, may become a potential effective therapeutic agent when prepared according to the specifications of the Homeopathic Pharmacopoeia and prescribed in accordance with Homeopathic standards.It uses medicines qualities rather than quantity.

Believes in minimum medication for any number of diseases or disease conditions.The Homeopathic medicines work so effectively because they work with nature, rather than against, the body’s inherent immune system. There are no additives, fillers, etcIt is neither habit forming nor fattening. Has no known side effects.

Homeopathy considers the body to be the best healing system around, and the symptoms are the body’s effort to heal. Homeopathic medicines stimulate the body’s natural ability to heal itself. A dose is considered as the number of times a remedy is taken, not the number of pellets or squirts. Homeopathy is safe during pregnancy, with babies, and animals. The treatment need not wait for the final diagnosis (of course diagnosis may help in treating the case) It can reach more where other systems do not have Penetration.

It treats the Person with the Disease rather than Disease in the Person

Homoeopathy adopts all the diagnostic measures to diagnose- treat- and monitor the treatment so that there is no mere removing of the symptoms but also annihilating the disease, specially life style changing healthy vegetarian food and of course Ashtanga Yoga.

Apart from general ailments, it can treat advantageously treat Asthma, sinusitis, Tuberculosis, allergic rhinitis etc. Depression, bedwetting, IBS, amoebiasis, Hemorrhoids, Fistula in Ano, Fissures, corns, warts, polyps, cysts, pre &Psot menopausal Syndrome, irritable children Autism, ADHD etc, above all Viral diseases like Swine flu, Dengue, chikungunya, Herpes Zoster etc.

The practioners need to be open minded &accept the wholisticapproach, look into other options like AYUSH while treating patients. Monitoring can be with the modern gadgets. There is saying “ Success is easy if you do not bother who takes the Credit “ Ultimately patient is not bothered about the type of treatment he is concerned with relief. Hence let the patient be the aim and not the type of Medical system.

PROFILE Prof. Madan Mohan, Director, Center for Yoga Therapy, Education and Research, Puducherry Prof. Madanmohan joined as Professor & Head, Department of Physiology, MGMCRI on 25.04.2012 after superannuating as Head, Dept of Physiology, JIPMER. He did his MBBS in 1968 from Jammu and Kashmir University & MD Physiology in 1974 from Delhi University. He completed PG Diploma in Yoga in 2005 and MSc Yoga in 2010 from Annamalai University. He was honored with DSc (Yoga) by SVYASA University, Bengaluru.

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Disscussion Preview 3 Integrating Yoga and Modern Medicine : Opportunities and Challenges Madanmohan and Ananda Balayogi Bhavanani

“Health for all by 2000 AD” has remained a pipedream. And can we achieve health for all even by 3000 AD? Unlikely. Unless we adopt an effective and integrative approach to the problem. The present health scenario is dismal. With increasing elderly population, the incidence of already prevalent chronic lifestyle disorders is on a steady rise. Antibiotic resistance is staring us in the face. Expensive high-tech modern medicine is beyond the reach of even the upper middle class. Public hospitals are over-crowded, understaffed and fund-starved. Millions die of chronic diseases while they are on life-long drug treatment. It is clear that allopathy does not have all the answers and there is an urgent need to adopt an integrative and holistic approach to the problem. There are gems in “alternative” treatment modalities which are simple, bio-eco-friendly and inexpensive. We need to shed our ego and get rid of “holier-than-thou” attitude.

Yoga can effectively augment modern medicine. Being holistic, it is ideal for integrated development of our body, mind as well as soul. Mind, body and soul are intricately inter-related and mind-body dichotomy is at the root of our problems and disease. Health as well as ill health have physical, mental-emotional as well as spiritual dimensions. Elderly persons are more happy and healthy if spiritually active. However, spiritual domain has been outside the scope of modern medicine. Yoga can effectively fill this lacuna. Yoga has promotive and preventive potential and can play an important role before the disease manifests itself. Yoga has many advantages. Being non-pharmacological, it is free from negative, harmful side effects of drugs. In contrast, it has positive, “side benefits” in terms of improvement of psychosomatic health of the patient. Even if drugs have to be given along with yoga therapy, decrease in drug dosage will bring down the cost of medicare & limit the side effects of drugs. Another advantage of yoga therapy is that treatment of one disease is associated with simultaneous benefit in other diseases as well as improvement in quality of life. Yogic relaxation and breathing techniques can be of immense value in pre-operative relaxation and post-operative recovery. It is clear that inexpensive and holistic yoga therapy can be great boost to our health care delivery system.

Great ventures are bound to face great challenges. The principle of duality (dvand) is inherent in our world. Change is always resisted due to uncertainty, even fear of unknown. We have to deal with status quo-ists who lack motivation and love laziness. Who has time? Well meaning professionals are busy in administrative work or private practice. The curriculum is already loaded, how to add new content? Another challenge is to identify and exclude unscientific, untested and potentially harmful methods. Powerful drug companies have vested interest in tutoring and pleasing physicians.

They are quite smart in modulating even the research findings! The task is stupendous, but worthy and achievable. We need to rope in competent, authentic and well meaning persons. We need visionaries who are scientists by training and action-oriented karmayogis. Use of internet will make the effort more effective, open and respectable. And Divine Grace will make the whole effort fruitful and enjoyable.

PROFILE Prof. ( Dr. ) G.GANA PATHY Joint Director (Retd) Former Professor and HOD, National Institute of Siddha,Tambaram B.S.M.S. & M.D. (Siddha )Selection, Committee Member, Ex- Member. Scientific Advisory Committee-Siddha.CCRAS, Ex - Member - Ayuneda, Siddha Unani Drugs - Technical Advisory Board. Ministry of health and Family Welfare Department, Indian System of Medicine and Homeopathy, Ex – Chairman & Member of Central Council of Indian Medicine, Faculty PRESIDENT, Siddha, CHAIRMAN. Board of Studies. Siddha,Chennai, Consultant, NRHM, Directorate of Indian Medicine and Homoeopathy), Chennai.

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Sri Balaji Educational and Charitable Public Trust Professor/HoD. Dept. of Kuzhandha Maruthuvam. National Institute of Siddha, Tambaram sanatorium.

• Three decades of sincere and dedicated service with enthusiastic towards the growth of Medical Students Community in Society.

• Performed duties and responsibilities at various levels from Asst. Lecturer to Joint Director Acted as DD, AIDS & Cancer wing at AAIGHM, Chennai. He has done Double blind clinical research for HIV & AIDS in MMC, Chennai.

Appreciation letters received from the Government of Tamil Nadu. Tamil Nadu Dr. M.G.R Medical University and from Indian Medicine and Homoeopathy Department. (thermal on the Good Work and the Best Practices initiated for the Development of Indian Medicine and Homeopath.

Received ‘”Distinguished Professor award” in the field of Siddha from TN Dr MGR Medical University-.

Tamil Nadu on 06-11- 2008.

Disscussion Preview 2 Traditional systems of Medicine Traditional systems of Medicine especially Siddha system of Medicine in Southern parts of India is becoming much popular for its unique value in treating and preventing ailments of mankind. Infection causes diseases and malnutrition causes diseases were more prominent in the beginning of the last century, but it was controlled in wealthy countries after introducing preventive measures like vaccines and nutritional food programs. Recent problems affecting mankind are malignancy, degenerative disorders, biochemical disturbances, mental illness and immunological disorders mainly genetic in origin. Chromosomal damages are due to radiation used in therapy, environmental pollution by drugs reactions and immoral behaviors. Siddha system treats both body and mind, prevents diseases and helps for longevity of life. Kaayakalpam is the main strength of the system. It helps for longevity of life by preventing diseases. It is not only by drugs, but by practices also. Apart from this, choice of drugs for anemia, arthritis, and skin disorders are more. Treating HIV and malignancy is possible. Drugs were tried for HIV in MMC, Chennai and Thoracic medicine hospital, Tambaram Sanatorium. During Chemotherapy supportive treatment can be provided to treat anemia, loss of appetite, etc. In drug resistant Tuberculosis, drugs in Siddha system is the best of choice. It was tried in Thoracic medicine hospital. Long back it was expected to know the antibiotic available in Siddha medicine and treatment for Asthma. In recent period, drugs for treating viral infections and malignancies are mainly expected.

There is more research scope for many diseases available in Siddha system. For successful achievements, support from Advance medical system is very much needed which will be discussed in detail during panel discussion.

Dr. P. Muralikrishna Reader, S.V.Ayurvedic College, Tirupati.

PROFILE

Dr. P. Muralikrishna did his B.A.M.S. at Nagarjuna University, Nagarjuna Nagar- Gold medalist (1986,A.P.), Doctor of Medicine in Ayurveda (Kayachikitsa) at Banaras Hindu University. Varanasi(UP) in 1993, Doctor of Philosophy (PhD) in Kayachikitsa –Panchakarma at S.S.University, Varanasi(UP) in 2005 and awarded in 2010, Doctor of Science (D.Sc) (Honoris causa) at Open international university for complimentary medicine, Colombo in 1997 for best professional activity in the field of Ayurveda and Post Graduate Diploma in Yoga at Banaras Hindu University, Varanasi(UP) in 1993.

Distinction in the ‘Shalya’ in final B.A.M.S. Examination – 1986.Divi Srinivasacharyulu Memorial A.P. State level silver medal for best scientific paper on the ‘Ayurvedic Approach to Skin 42

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Sri Balaji Educational and Charitable Public Trust Diseases – Vijayawada’ – 1985. Chavali Ramaiah Memorial Gold medal for outstanding performance in B.A.M.S. Examinations at Nagarjuna University, Vijayawada – 1986. Achanta Lakshmipathi Memorial Gold medal for best performance in all five years B.A.M.S. Examinations at Nagarjuna University level – 1986. Friendship cash award for having come first in Kayachikitsa & Salya salakya in final year B.A.M.S. Exams – 1986. Sri.N.Ranganadhacharyulu Memorial Cash award for getting first rank in Nagarjuna University level final B.A.M.S. Exams – 1986.

National awards: Vaidya Ramnarayana Sharma memorial Baidyanath foundation award in 1992 for best scientific paper in All India Post Graduate level scientific paper competitions on “Scientific basis of Ayurvedic Diagnostics”, Nagpur – 1992. Outstanding young Indian” a National award was received from Junior Chamber International India at its national conference held at Bangalore on 27th December, 2006 by recognizing outstanding performance in the field of science and its application to the society.

PUBLICATIONS:- Twenty five papers were published in peer reviewed national medical journals.

Editor of “Basavarajeeyam” (English translation of a book on Ayurvedic therapeutics of medieval period) published by CCRAS, New Delhi. RESEARCH PROJECTS:- Headed ten clinical and experimental research projects. Seventy five papers were presented in national and international seminars. Monitoring committee member to three projects of Department of Science and Technology on Science initiative in Ayurveda “Effects of Amalaki Rasayan on aging and DNA repair” funded by Principle Scientific Adviser (PSA), Department of Science & Technology, Government of India, New Delhi.

Steering subcommittee member of AYUSH to ensuing five year plan. National guest speaker for ROTP/ CME programs conducted by many Ayurvedic colleges of India, extensively travelled all over India and given Guest lectures on Ayurveda in many reputed Ayurvedic institutions in India. Technical expert committee member to Draft a” Document on Ayurveda” submitted by Government of India to World Health organization at Geneva, on 21-08-2012. Expert member of Syllabus framing committee in the subject of Panchakarma to Graduate and post graduate courses of Ayurveda, 2012.

Expert Committee member to review and finalize the document ‘ON EVIDENCE BASED AYURVEDIC REMEDIES/THERAPIES BASED ON RESEARCH WORK DONE” a project of WHO organised at National Institute of Indian Medical Heritage (Formerly Known as Indian Institute of History of Medicine), 2011 and given more than 10 Radio talks on different topics of Ayurveda and Health.

Disscussion Preview 5 Potentials of Ayurveda and medical pluralism Dr P.Murali krishna, M.D(Ay), Ph.D Reader, PG Department of Panchakarma, TTD’s S.V.Ayurvedic College, Tirupati-517507(AP)

AYURVEDA an indigenous medical wisdom has its roots in Vedas and taking care of health needs of Indian society from time immemorial. It is a comprehensive health care system with well construed basic tenets, time tested formulary and unique Bio-purification technique (Pancha karma).

This indigenous medical system literally called as ‘Science of Life’ give due importance to positive health care of individual by advocating special diet regimens, lifestyle regulations and drug administration suite to person, place and seasons. Its unique approach of treating the patients is individualized with threefold schedule of drug, diet and lifestyle to mitigate the entire disease process, thus restore the health.

The potential areas of Ayurveda in health and medical care management are as follows 1.’

Rasayana’, a class of drugs having the quality of slowdown the biological aging, and immuno-modulator effect. 2. Panchakarma, five types of Bio-purificatory measures to eliminate the pathogens from the body through natural orifices and also to sensitize the body for subsequent drug therapies. 3. ‘Kshara sutra’ a para surgical technique of applying medicated thread in ano-rectal fistulae is well appreciated for its efficacy in healing the tracks and preventing the recurrence. 4. time tested and effective herbal and herboSANJEEVITA 2013

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Sri Balaji Educational and Charitable Public Trust mineral formulae in the management of allergic skin & respiratory diseases, acid-peptic disorders, IBS, Psoriasis, Auto-immune diseases, selective neurological disorders, Rhumatological diseases, Genitourinary disease, male and female infertilities, Neuro-degenerative disorders, refractive errors of eye and migraine. Ayurveda has unique role in offering safe and effective remedies in management of above short listed conditions.

In the era of medical pluralism no system is absolute in catering the health needs of society.

Openness, acceptability, honesty and patient oriented outlook which are very essential for any physician who has sole responsibility of safe guarding the health and life of patient. The physicians of Ayurveda, though they have special approach in diagnostics but depend on investigative procedures of contemporary modern medicine to have precision in diagnosis. In specific infective conditions like tuberculosis, intensive care, medical and surgical emergencies the patients are referred to specialists of modern medicine where an effective and life saving management can be expected. In growth disorders Homoeopathy has safe and cheap remedies. In specific skin disesases like vitiligo, Unani system has effective treatments. Siddha system has its unique role in offering quick and effective remedies with herbo- mineral combinations. All these medical system have their own way of medical care, which are unapproachable and incomprehensible to physicians of other systems. There is a need of openness and transparency of thought in exchanging the views among the physicians to offer most effective, safe and economy remedies for simple to fatal ailments. Carak Samhita, an Ayurvedic classic of Ancient India quotes that ‘a team of doctors are best to evolve an undoubted remedies’. Every system has its own potential area and unique role in health and medical management. The greatness of these systems is segregated and pocketed. There is need to bring these potentials of various systems in to a common flat form and used for social application. The main short comings achieving medical pluralism in India are undue claims, lack of concern over patient, myopic thinking, commercialization and lack of class professionalism in practitioners. If we overcome these dark areas of thinking, medical pluralism and integrative approaches are going to offer safe, cheap and effective remedies to the needy.

Sanjeevita Motivational Lecture Chairperson : Prof. S.Chandrasekar, Fmr Director, JIPMER

PROFILE Marthanda Varma Sankaran Valiathan Ch.M, FRCS, FRCS (C), FRCP, D.Sc (h.c) “Rasayana (rejuvenation) in tradition and in recent studies” Prof. M.S. Valiathan, National Research Professor , Manipal University, Manipal, Karnataka

Professor M.V.S Valiathan (b 1934), graduated in medicine from the Kerala University and received training in surgery in the UK with subsequent specialization in cardiac surgery in the US. He became a Fellow of the Royal College of Surgeons of England in 1960 and a Master of Surgery from the University of Liverpool two years later. He received the Fellowship of the Canadian Royal College in cardiac surgery in 1970.

Professor Valiathan served on the faculties of the Georgetown University Hospital, Washington; Postgraduate Medical Institute, Chandigarh and IIT, Chennai (Biomedical Engineering) before moving to Trivandrum as the architect of the Sree Chitra Tirunal Institute, Trivandrum where he remained as Professor of Cardiac Surgery and Director for twenty years. After leaving the Chitra Institute, Professor SANJEEVITA 2013 44

Sri Balaji Educational and Charitable Public Trust Valiathan served as the first Vice-Chancellor of the Manipal University. He is a Past-President of the Indian National Science Academy, Association of Indian Universities and currently, a National Research Professor.

Professor Valiathan’s professional and scientific interests were cardiac surgery in children, studies on the causation of a tropical heart muscle disease, and the development of technology for cardiovascular devices. He has published a monograph and many scientific papers on these subjects. More recently he has published a series of three volumes based on the classics of Charaka, Suśruta and Vagbhata. A new book “An Introduction to Ayurveda” was published recently.

He is a recipient of many national and international honours, honorary doctorates and Awards including the Padma Vibhushan by the Government of India in 2005.

ABSRACT 5 RASAYANA (REJUVENATION) IN TRADITION AND IN RECENT STUDIES*

Rasayana is one of the eight branches of Ayurveda and has been in vogue for over two thousand years. It remains popular even today and drugs for rasayana are among the top selling products in Ayurvedic formulary.

While ageing is a natural process which cannot be prevented, rejuvenant therapy is based on the concept that the infirmities associated with ageing could be prevented. The key principle of rejuvenant therapy is to smoothen the pathway of nutrients to replenish body tissues which are always depleting and degrading. Rejuvenant therapy was carried out in two modes – intramural and extramural. As the intramural method called for indoor facilities and involved many restrictions, the extramural method – simpler and hassle free – has been more popular.

There have been studies of rejuvenant procedures in the past, which looked at gross effects such as “feel good factor” etc., which provided little evidence of rejuvenation at the biological level. Recently two published studies have shown that Amalaki Rasayana significantly reduces breaks of single and double strand DNA in the neurons and astrocytes of rats (Subba Rao); and confirm that it enhances the life span, fecundity, thermal tolerance, starvation tolerance and other biological markers in drosophila (Lakhotia). These studies form part of a new initiative – Ayurvedic Biology – which consists of rigorous studies in modern science based on cues from Ayurveda. __________________________________________________________________________________ * Integrative Medicine Annual Summit, Sri Balaji Vidyapeeth University, Mahatma Gandhi Medical College Campus, Puducherry. 6th September, 2013. ** National Research Professor, Manipal University, Manipal – 576 104 msvaliathan@gmail.com

Sanjeevita Valediction

Summit Integration Prof. A. R. Srinivasan, Registrar Sri Balaji Vidyapeeth Prof. Dept of Bio chemistry,MGMCRI PROFILE :

Dr.A.R.Srinivasan did his Post graduation in Medical Biochemistry from CMC Vellore and was placed first in Madras University. He is a recipient of the fellowships from UGC and CSIR. His Doctoral thesis was on the microbial enzyme, phenylalanine ammonia-lyase. Dr.A.R.Srinivasan is a co-inventor SANJEEVITA 2013

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Sri Balaji Educational and Charitable Public Trust of a patent that pertains to enzyme therapy for phenylketonuria known as Dr.Vellore A.R.Srinivasan. In the classical music circles, he is a carnatic vocalist, composer and percussionist.

His original compositions are more than 1500 and Dr.Srinivasan has been featured in several TV channels including CNN-IBN. With over two decades of experience Dr.A.R.Srinivasan is presently professor of Biochemistry, MGMCRI with the additional responsibility of serving as Registrar, Sri Balaji Vidhyapeeth.

SUMMIT INTEGRATION PREVIEW Sanjeevita 2013 has opened up newer vistas in the current concepts underlying integrative medicine.

Renowned scientists, academicians, medical educationists and students drawn from various parts of our country have gathered under this single roof to help enable the delegates partake of rich and wide knowledge, besides providing discerning and specific information. This acquires significance in this era of information explosion and dissemination of information pertaining to multidisciplinary facets.

The healthy mix of scholarly lectures, theoretical workshops, panel discussion and poster presentations have carved a niche for sanjeevita 2013.

The organizers have performed a stupendous job in requesting eminent speakers Padmabhushan Prof.M.S.Valiathan, Prof. K.R.Sethuraman, Dr.Sameul JK Abraham, Prof. S.P.Thyagarajan, Prof.M.Prakash Rao,Prof.B.D.Patel,Prof.MadanMohan,Prof G.Ganapathy,Prof.PH Ananthanarayanan and Dr.P.Muralikrishna

Sanjeevita 2013 has created waves and hopefully it would pave the way for several such summits in future. Long Live Science, Long Live Scientific temper!!.

Poster Competition Theme: Concept of “ Rejuvenation – Traditional and Modern” ABSTRACTS PS1. Cognitive Functions in Children with Poor School Performance Manoharan Vijoo Anto Prabhu, Abdulmajeeth Anzar, Chandrasekaran Venkatesh, Palanisamy Soundararajan, Dhandapany Gunasekaran, Sadagopan Srinivasan.

Department of Pediatrics, Mahatma Gandhi Medical College & Research Institute, Pillayarkuppam, Pondicherry - 607402 Abstract

Cognitive impairment, referred to as intellectual disability, describes the condition of a child whose intellectual functioning level and adaptive skills are significantly below the average for a child of his chronological age. Children with a cognitive impairment can be successful in school and lead fulfilling lives. This study aims at assessing the cognitive function among young children with poor scholastic performance using The Mini Mental State Examination. Three out of five children had cognitive impairment, attributed to underlying seizure disorder, tik disorder and a family history of psychiatric illness respectively, whereas two children had a relatively better cognitive function. Poor school performance can be associated with cognitive impairment. Attempts to improve cognition might improve their scholastic performance.

PS 2. Rejuvenation of ‘Project Rejuvenation Dr. K. Henri Balraj, and Miss. Suvadha, K. Department of Physiology, Mahatma Gandhi Medical College & Research Institute, Pillayarkuppam, Pondicherry - 607402 46

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Sri Balaji Educational and Charitable Public Trust Abstract

Personality is an onion. As per Freud the inner most peel being desires (id). Ego an outer peel controls id. Theologians trade the concept that it is either ego or Theo. Theo being God in Greek.

God centred philosophy is the best philosophy – leading to passion. Passion is a forerunner of performance.

Enthusiasm is the father of excellence. With passion and enthusiasm comes a healthy love of self and heightened self esteem. Equipoise sets in, and a meditative and focused mind develops. Sharing here occurs when great souls get individuals to move along. Doing small things in a great way is excellent.

It is, to be with the leader and to fall by the system.

PS3. Bioactive properties of the Grey Goblin fish Minous Monodactylus (Bloch and Schneider, 1801) from Parangipettai coastal waters south east coast of India.

N. Prithiviraj and R.Rajesh,D.Annadurai Centre of Advanced study in Marine Biology, Faculty of Marine Sciences, Annamalai University, Parangipettai-608 502,Tamil Nadu,India Abstract

Objective: To investigate the bioactive properties of the Grey Goblin fish Minous Monodactylus .Methods: Live M.monodactylus fishes were collected from Parangipettai coastal waters, Tamilnadu, India. The dorsal, pelvic spine were cut from the base and homogenized in normal saline at pH 7.4.

The partial purification of protein was carried out using DEAE cellulose. An antimicrobial property of the purified protein was tested against five pathogenic bacteria and five pathogenic fungi by using disc diffusion method. The toxicity study of fish was primarily done using heamolytic assay and cell line assay (Mcf 7 cell line).Further characterization was done through FT-IR. The amino acid present in the venom was screened using HPLC by comparing the Rf value of 21 standard amino acids. Result: The antimicrobial activity shows mild activity on bacteria not on fungai. The spine venom exhibited high toxicity upon testing with erythrocytes and cell line culture assay. Glutamic acid, Aspartic acid, Phenyl alanine, Threonine ,Tyrosine, Proline are the amino acid present in spine venom (HPLC), FTIR analyze revealed the presence of bioactive compounds signals at different ranges. Conclusion: This study reveals that crude grey goblin fish spine venom could be used to isolate structurally unique compounds of specific biomedical activities.

PS4. Rejuvenation therapy for allergic rhinitis P. Karthikeyan, Dr.Rathan Shetty K.S., Dr.Davis Thomas P. Department of ENT, Mahatma Gandhi Medical College & Research Institute, Pillayarkuppam, Pondicherry - 607402 Abstract:

Allergic rhinitis represents an inflammatory condition of the nasal mucosa as a result of an exaggerated immunoglobulin E (IgE)-mediated immune response to inhalant allergens. Allergic rhinitis has a tremendous impact on the quality of life and productivity of those it affects. Holistic management of allergic rhinitis requires an understanding of external environmental factors, internal environmental factors (i.e., personality and stress-management styles), and inflammatory drivers that underlie the symptoms. Reducing stress is also a crucial component of improving the immune system and decreasing mast cell sensitization. Treating this condition goes far beyond anti-histamines; it requires downregulation of inflammation through long-term nutritional supplementation, dietary modification, stress reduction and, elimination of environmental triggers. Rejuvenation therapy not only clear symptoms of allergic rhinitis, but they also help the body come into balance, clearing the underlying condition causing allergies and improving overall health.

Acupuncture can treat the symptoms locally by placing small, sterile needles right on points of pain or symptoms like the head or side of nose, allowing the stuck energy to dissipate and move more smoothly throughout the body. Chanting and humming in yoga, create sound vibrations which SANJEEVITA 2013

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Sri Balaji Educational and Charitable Public Trust encourage airflow between sinus membranes and nasal passages. These practices help enhance proper sinus drainage. Nasal congestion can be improved with the use of a neti pot, wherein saline solutions are used for relief of symptoms. Saline solutions help break up tenacious mucus. Stress and anxiety both tend to aggravate the symptoms of allergic rhinitis and art therapy helps by relaxing the patient and reducing anxiety. Essential oils provide relief from nasal congestion in three ways: improving nasal airflow by inducing vasoconstriction, stimulating cold receptors and stimulating kappa-opioid receptors for pain relief. Cardio exercise reduces the symptoms of sneezing, congestion, nasal itching and nasal discharge, by increasing adrenaline levels and increasing blood flow to nasal mucosa. Hypnosis gives people with asthma or allergies more self-discipline to follow good health practices. Stress and anxiety cause airways to constrict more in patients with asthma or allergies. Music therapy helps to relax and reduce anxiety, thereby stabilizing the autonomic nervous system.

PS5. Health, rejuvenation and longevity: an ayurvedic perspective Madanmohan and Ananda Balayogi Bhavanani Department of Physiology and CYTER, Mahatma Gandhi Medical College & Research Institute, Pillayarkuppam, Pondicherry - 607402 Abstract

WHO defines health as “A state of complete physical, mental and social well being and not merely the absence of disease or infirmity”. Acharya Sushrut (600 BC) has given a poetic and holistic definition of health as: “Balanced elements, normal digestive & excretory functions, content & happy mind & atma; these are the signs of health” (Sushrut Samhita, Sutrasthanam, 15:41). Charak (~200 BC) is in agreement with this definition when he says: “Disequilibrium of elements is disorder and their equilibrium is health. Health is happiness while disorder in unhappiness” (Charak Samhita, Sutrasthanam, 9:4). Physiological wisdom implies that being healthy means our ability to maintain homeostasis and milieu interieur by co-operative functioning of our organs/ systems.

Yoga is a holistic science. From the yogic point of view, total health implies health of and harmony between body, mind as well as soul. Keeping the above in mind, I would like to give a concise definition of health as: “Health is a state of holistic well-being enabling one to work enthusiastically and selflessly and enjoy the work as an offering to the Divine”. Working with enthusiasm implies physical health and enjoying one’s work promotes mental health. Working selflessly for common good and offering the fruits of one’s labor to the Divine is a concrete way to promote social and spiritual health. This is nishkam karmayoga, the central message of Bhagavadgita.

Vedic & ayuv vedic term Ayush implies long & healthy life and ayushkar are the measures that prolong life beyond 100 years. A Vedic verse prays thus: “May we live for 300 years (traayusham) like devatas and rishis” (Yajurved, 6:62). Longevity in determined by the interaction of our genes and environment and supervised by our consciousness. We can enjoy /long & healthy life by adopting healthy lifestyle & yoga is the best lifestyle ever designed. Ayurved describes two types of therapeutics: i) alleviation of disorders & ii) promotion of strength in a healthy person (Charak, Samhita, Chikitsasthanam, 1:1,4). The second category include vrishya that enhance sexual potency (Vajikaran) and rasayan that promote strength and immunity although they can alleviate disorders also. Amalaki and ashwagandha are examples of rasayan (that provide ras or “juice of life”) Which improve physical & mental health and delay aging process.

PS6. Yoga and modern medicine: need for integration Madanmohan and Ananda Balayogi Bhavanani Department of Physiology and CYTER, Mahatma Gandhi Medical College & Research Institute,Pillayarkuppam, Pondicherry - 607402 Abstract

Modern medicine has made tremendous progress in recent years with state of the art diagnostic methods, powerful drugs and awesome surgical techniques. However, allopathy does not have all the 48

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Sri Balaji Educational and Charitable Public Trust answers as it is basically disease oriented. Its services are expensive and beyond the reach of common man and drugs have many harmful side effects. It is far from effective in stress-based, chronic degenerative, old age and lifestyle disorders which are the bane of modern society. On the other hand, yoga is holistic because it has promotive, preventive as well as curative potential. It is not only free from the negative side effects of drugs, but has “positive” beneficial side benefits in terms of improvement of psychosomatic health. In early uncomplicated stages of diseases it can be used as an effective alternative to drugs. In later stages, it can be used as an effective lifestyle adjunct to medical treatment to reduce drug dosage and improve quality of life. It is most effective for prevention as well as management of all–pervading stress and stress disorders. However it is no match to allopathy in the management of acute infections and medical and surgical emergencies. It also needs to be emphasized that without discipline and commitment to yoga, compliance is a big question mark. Yoga and modern medicine are natural allies and their coming together is inevitable and long overdue. Their merger will give us a more effective and holistic health science that will be a boon to humanity. To achieve this goal, we need a group of committed intellectuals who are scientists by training, yogis by heart and action-oriented karmayogis.

Without such a holistic vision and action, we will not be able to achieve health for all even by 3000 AD, Health for all by 2000AD was a pipe dream.

PS7. Effect of yoga training on cardiorespiratory health in obese subjects Madanmohan*, Ananda Balayogi Bhavanani*, AR Srinivasan’ and Balanehru Subramanian• *Department of Physiology and CYTER, MGMC & RI ‘Department of Biochemistry MGMC & RI •CIDRF, MGMC & RI. Abstract:

Obesity is a major health challenge worldwide. It is a contributing factor to morbidity and mortality in lifestyle disorders such as diabetes, hypertension, coronary artery disease and premature aging. Yoga is the best lifestyle ever designed for preventive health as it also promotes positive wellbeing.

Studies have suggested the beneficial effects of yoga in prevention and management of obesity and its complications. However, the cardiorespiratory health benefits of yoga in obesity have not been studied in detail. The present single blind RCT aims to determine cardiorespiratory health status of obese subjects (BMI 25 - 40) and evaluate the effect of Yoga training in them. 120 obese volunteers (BMI 25 - 40) will be recruited and randomized into yoga group (60) and wait list control group (60). Cardiorespiratory health status will be evaluated by anthropometric indices (Ht, Wt, BMI, WC/HC), physiological parameters (resting HR, BP and HRV, PFT and exercise tolerance), Ferrans and Powers QoL Index and biochemical parameters (HOMA, micronutrients, LFT, lipid and thyroid profiles) before and after the study period and appropriate statistical analysis will be done. 12 weeks of Yoga training consisting of an integrated schedule of asan, pranayam and relaxation techniques along with lifestyle modifications and Yogic counseling will be given to Yoga group. Participants in control group will be treated as wait list control and will be given an opportunity to attend yoga training programme after completion of study period. A significant improvement is expected in cardiorespiratory health status that will be an indicator of the preventive and health promotive effects of Yoga.

PS8. Yoga works, but how?

Ananda Balayogi Bhavanani, Meena Ramanathan, and Madanmohan.

Department of Physiology and CYTER, Mahatma Gandhi Medical College & Research Institute, Pillayarkuppam, Pondicherry - 607402 Abstract

We are today faced with numerous debilitating chronic illnesses related to aging, environmental pollution, and hedonistic lifestyle.These disorders include cancer, diabetes, osteoporosis, and cardiovascular diseases as well as many incurable diseases such as AIDS. Modern medical advancements provide the rationale for the integration of various traditional healing techniques including Yoga to promote healing, SANJEEVITA 2013

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Sri Balaji Educational and Charitable Public Trust health, and longevity. It is imperative that advances in medicine include the wholistic approach of Yoga to face the current challenges in health care. The antiquity of Yoga must be united with the innovations of modern medicine to improve quality of life throughout the world. While modern medicine has a lot to offer humankind in its treatment and management of acute diseases, accidents and communicable diseases, Yoga has a lot to offer in terms of preventive, promotive and rehabilitative methods in addition to many management methods to tackle modern illnesses. While modern science looks outward for the cause of all ills, Yoga enables us to search deep within our own self. This two way search can lead us to many answers for the troubles that plague modern man. Numerous studies have been reported in recent decades on the psycho-physiological and biochemical changes occurring following the practice of Yoga.

We discuss some of the researched benefits to facilitate an understanding of how Yoga works at least at the physical level, though we are yet to research and understand subtler effects of Yoga.

PS9. Immediate cardiovascular effects of pranayamas in patients of hypertension Ananda Balayogi Bhavanani and Madanmohan Department of Physiology and Director CYTER, Mahatma Gandhi Medical College & Research Institute, Pillayarkuppam, Pondicherry - 607402 Abstract

Hypertension is a common disorder where Yoga has been shown to be an effective adjunct therapy. Different pranayamas have been studied in patients of hypertension and this presentation deals with postulated mechanisms behind healthy reductions in heart rate, systolic pressure (SP), diastolic pressure, mean pressure and blood pressure (BP) indices such as rate-pressure product and double product. Beneficial immediate results of sukha (inhalation = exhalation), savitri (6:3:6:3 rhythm for inhalation: held in: exhalation and held out breath in sitting and supine positions), chandra nadi (exclusive left nostril breathing) and pranava pranayamas (using audible AUM chanting during prolonged sequential exhalation in sitting and supine positions) are detailed. These changes may be attributed to a normalization of autonomic cardiovascular rhythms as a result of increased vagal modulation and / or decreased sympathetic activity and improved baroreflex sensitivity along with an augmentation of endogenous nitric oxide production. The prolonged exhalation phase of pranava pranayama may be mimicking the Valsalva maneuver resulting in decreased venous return, cardiac output and SP. These findings have potential therapeutic applications in day-to-day as well as clinical situations where BP needs to be brought down at the earliest. These simple and cost effective techniques may be added to the management protocol of hypertension in addition to regular medical management.

PS10. “OIL PULLING”-A TRADITIONAL REJUVENATION P.Saranya and Shilpa Philip Mahatma Gandhi Medical College and Hospital, Pillaiyarkuppam, Pondicherry- 632007 Abstract

Ayurveda is the holistic system of medicine which evolved in India some 3000-5000 years ago.

The system of traditional medicine native to Indian subcontinent now practiced in other parts of the world in the form of complimentary or alternative medicine. Oil pulling is the ancient ayurvedic remedy for oral health and detoxification. It involves the use of pure oils as agents for pulling harmful bacteria, fungus and other out of the mouth. Oil therapy is preventive as well as curative and is the simple rejuvenating treatment. Ayurveda advises oil gargling to purify the entire human system. This poster highlights the ‘oil pulling’ system of rejuvenation therapy, which not only improves the oral health but also improves the systemic health.”Let wellbeing prevail” for all.

PS 11. Traditional Medicines in remineralization of early enamel caries Dr. Sanguida. A, and Dr. Carounanidy Usha Indira Gandhi Institute of Dental Sciences, Sri Balaji Vidyapeeth, Puducherry.

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Abstract

Dental caries is one of the mankind’s ancient diseases. This disease has multifactorial causes and manifests as a carious lesion. The genesis of an established carious cavitation begins with incipient demineralization of the hydroxyapatite building blocks of the enamel superstructure. It is possible to rejuvenate or repair such an incipient lesion by enabling remineralization of the demineralised areas.

This forms the rationale behind the modern concept of remineralization of dental caries using minerals such as fluoride, calcium and phosphate. The pride of this concept is in being non- invasive in contrast to surgical restorative treatment of the lesion.

Traditional herbal medicines have been found to have anticariogenic potential. However the remineralization capacity of the herbs in par with fluorides, as effective remineralization agents is an unexplored area in caries prevention. Hence this poster will highlight the various herbs possessing anticariogenic and remineralization properties that can be used as potential tools in caries disease prevention.

PS12. Stem cells and rejuvenation in Otolaryngology Satvinder Singh Bakshi Department of ENT, Mahatma Gandhi Medical College and Hospital, Pillaiyarkuppam, Pondicherry632007 Abstract

Cell based therapies are one of the most exciting and rapidly advancing areas of scientific work and have found useful applications in all fields of medicine including otolaryngology; however their practical application in the field of otorhinolaryngology is still at an nascent stage. Cell based therapies can be used as direct transfer of stem cells into the body or by generating specific tissue in vitro and later transferring the tissues into the affected site. Here, through this poster I endeavor to highlight work already done in the field of cell based therapy in otolaryngology and project its possible practical application into common debilitating diseases like oral submucus fibrosis and physiological dysfunctions like anosmia and deafness.

PS13. Green leaves for oral life.

Dr.N.Manimegalai, Dr.CH.R.Arun kanth, Dr.K.Vivek Pediatric and Preventive Dentistry, Indira Gandhi Institute of Dental Sciences, Pondicherry.

Abstract

The importance of mouth and teeth cleanliness has been recognized from the earliest days of civilization to the 21st century. Oral diseases are major health problems, with dental caries and periodontal diseases among the most important preventable global infectious diseases. Oral health influences the general quality of life and poor oral health is linked to chronic conditions and systemic diseases. Dental caries and periodontal diseases is one of the most prevalent diseases in humans. Endogenous oral bacterial species play a major role in the initiation and progression of these diseases. Effective prevention can be achieved by mechanical plaque removal or chemical agents used in the form of either dentifrices or mouth rinses. While several agents are commercially available, these chemicals can alter oral microbiota and have undesirable side-effects such as vomiting, diarrhea and tooth staining. Given the incidence of oral disease, increased resistance by bacteria to antibiotics, adverse affects of some antibacterial agents currently used in dentistry and financial considerations, there is a need for alternative prevention and treatment options that are safe, effective and economical. Hence, the search for alternative products continues and natural phytochemicals isolated from plants used as traditional medicines are considered as good alternatives. Recently, there has been a growing trend to seek natural remedies as part of dental treatment and this approach may be termed phytotherapeutics or ethnopharmacology.

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Sri Balaji Educational and Charitable Public Trust PS14. Treating premalignant oral cancer using Chyawanprash Awaleha - a Genopotective agent Uma.A.N, Dhananjay.S.K, Tirou Aroul.T, A.Lokeshmaran Mahatma Gandhi Medical College and Research Institute, Puducherry Abstract

The single greatest risk factor for oral cancer in the India is the use of tobacco, which accounts for 75% of all cases of oral cancer. Apart from grading of premalignant lesions, cytogenetic test in such tobacco chewing patients are good prognostic indicators for monitoring genetic damage in human population. The test results may be used as a tool for genetic counseling, intervention for tobacco cessation, early treatment and disease management. Cytogenetic study was thus performed on six tobacco chewers suffering from premalignant lesion and compared with six, age and sex matched healthy controls. The frequency of Mitotic index (MI), chromosomal aberrations (CA), premature chromosome separations (PCD) and satellite associations (SA) were analyzed. The ‘p’ value was statistically significant in the patients than that of the control. As a counseling measure, the patients were advised for tobacco chewing cessation and were asked to follow a strict bland diet. They were also fed with 20 gms of Chyawanprash awaleha (Cp), twice a day for three months. At the end of three months, the genopotective efficacy of Chyawanprash awaleha (Dabur) was investigated on the somatic chromosomes of the patients and the same six control individuals. The frequency of MI, CA, PCD and SA were analyzed and the results were compared with the earlier values. All the parameters not only showed a significant decrease in the p value (P<0.01) but the value had almost come to the level of controls indicating that Chyawanprash has minimized the genotoxic risk caused by mutagenic agents present in tobacco. Thus traditional medication seems to be the need of the hour which may provide the cure of such premalignant oral cancer patients lead a normal healthy life.

PS15. Aloe vera as Karpaaviztha G.Thirunarayanan, J.Samooga Neethi, P.Shanmugam, G.Anbarasi Sivaraj siddha medical college, Salem, Tamilnadu.

Abstract , The hallmark of traditional Siddha system is KAYAKARPAM.The word refers “Kaya” means Body and “Karpa” means strong as stone”.Hence it together means keeping the body as strong as stone.

Uncountable number of herbs has been used as karpa avizthas. Here I discussed about Aloe vera.

Its tamil name Kumari itself explains its rejuvenation property. Aloe Vera is a succulent plant and part of the lily family (Liliaceae). Aloe Vera is a powerhouses of antioxidants,antibiotics work as stimulator of cell growth and have scar and pain inhibitor properties and contains over 200 active components including vitamins, minerals,amino acids,enzymes,polysaccharide,fatty acids and phytochemicals such as aloin,glucommannans,salicylic acid,tannins,flavonoids,terpenoids,carbohydrates, and alkaloids -no wonder it’s used for such a wide range of remedies.The bulk of the Aloe vera leaf is filled with a clear gel-like substance, which is approximately 99% water.

Due to its components it :

Halts the growth of cancer,Lowers high cholesterol. Repairs “sludge blood” and reverses “sticky blood”,Boosts the oxygenation of your blood,Eases inflammation and soothes arthritis pain. Protects the body from oxidative stress. Prevents kidney stones and protects the body from oxalates, Protects the kidneys from disease. Alkalizes the body,Cures ulcers, IBS, Crohn’s disease and other digestive disorders.

Reduces high blood pressure by treating the cause.Boosts cardiovascular performance and physical endurance. Nourishes the body with minerals, vitamins, enzymes and glyconutrients. Lubricates the digestive tract, ends constipation, Stabilizes blood sugar and reduces triglycerides in diabetics, Prevents and treats candida infections. Accelerates healing from physical burns and radiation burns,Speeds recovery from injury or physical exertion, Hydrates the skin, accelerates skin repair.

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Sri Balaji Educational and Charitable Public Trust PS16. MUSIC-A TOOL FOR PAIN MANAGEMENT IN NEONATES Dr.Anup John Thomas, Dr. Raja Ramalingam Department of Pediatrics, Mahatma Gandhi Medical College and Research Institute, Puducherry Abstract

Infants treated in a neonatal intensive care unit (NICU) are exposed to a variety of painful procedures such as heel prick, IV cannula insertion, endotracheal suctioning, etc. and to environmental stress such as noise, light, etc. Many studies have shown that repeated and sustained pain can have direct and long-term consequences on the neurological and behavior-oriented development of the neonates during the rapid development phase of the central nervous system.

The purpose of this study was to examine the effects of music therapy as a non-pharmacological intervention on the improvement of physiological outcomes such as oxygen saturation and heart rateas well as the behavioral state such as crying or facial expressionin the neonates during routine heel prick procedure.

First group of five neonatesreceived music therapy in the form of recorded lullaby song during heel prick and second groupof another five neonates did not receive any music intervention during procedure.

It was observed that music therapy had a significantly beneficial effect on Infantsâ&#x20AC;&#x2122; physiologicalresponses and behavior. Reductions in heart rate, lessamount of oxygen desaturationanddecreased crying time was noted when compared to those who did not receive any music intervention.

Music is a low cost yet a valuable resource for pain management during painful procedures andcan be used as a therapeutic option in neonatal care.

PS17. Myths and facts of Ayurvedhic medicine in dental diseases and conditions Dr.R.Ilangkumaran and P.S. Manoharan Department of Prosthodontics, Indira Gandhi Institute of Dental Sciences, Pondicherry.

Abstract

Ayurvedha is one of the ancient Indian systems of health care, which have been in use through years and its role of healing in dental diseases was transferred from one generation to the next and through scriptures, hearsay evidence. Although many myths do exist in the practice of ayurvedhic medicine, some have been substantiated as facts with evidence based medicine. This poster depicts the myths and facts of the ayurvedhic medicine and the research demands in present day evidence based dentistry.

PS18. Ayurvedhic intervention in Prosthodontics - State of evidence and future perspectives Soumo Ghoshal and J. Srinivasan Dept. of Prosthodontics, Indira Gandhi Institute of Dental Sciences, Pondicherry.

Abstract

Prosthodontics is the branch of dentistry deals with replacement of teeth and associated structures with artificial substitutes. Ayurvedhic medicine with herbal extracts have been used traditionally as astringent, antifungal, antibacterial, anti-inflammatory, sialogogue and analgesic to treat general ailments.

There is a phenomenal scope for these herbal extracts to be used with above mentioned properties in rehabilitation with dentures. This poster is aimed to outline the existing state of evidence of ayurvedhic medicine in such conditions and their potential scope of their use in Prosthodontics. The poster also provides guidelines and directions for future perspectives and their scope in the field of research.

PS 19. Rejuvenation in Aging.

A Santha Devy and Suganya.R Dept. of Oral Pathology, Indira Gandhi Institute of Dental Sciences, Pondicherry.

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Sri Balaji Educational and Charitable Public Trust Abstract

Rejuvenation is reversal of aging process which is quite different and distinct from life extension and thus requires a different strategy. It may be repair of the damage that is associated with aging or replacement of damaged tissue with new tissue thereby, rejuvenation can be a means of life extension.

This can be achieved by various methods and strategies among those the role of telomerase has been highlighted in the reversal of aging process. Telomerase is an enzyme that synthesizes the specific DNA sequence at telomeres, i.e., the terminal DNA at the ends of all chromosomes. Telomeres are essential genetic elements responsible for protecting chromosome ends from being recognized as “broken DNA.” Because telomeric DNA cannot be fully replicated by conventional DNA polymerases, and because telomeres undergo degradative processing and are a “hotspot” for oxidative damage, telomeres will gradually shorten with time and cell division unless there is sufficient telomerase activity to maintain telomere length. It has been regarded as a mitotic clock that controls cellular ageing. Whenever the cell goes for division and proliferation there is a reduction at the telomeric end .This poster presents the role of telomerase and how it aids in reversal of aging using anti-oxidant supplements and natural products available.

PS 20. Rejuvenation by host modulation in Periodontics Pratebha B., Anitha K., Janani N., and Sarvana Kumar Dept of Periodontology, Indira Gandhi Institute of Dental Sciences, SBV University, Pondicherry.

Abstract

Periodontitis is a complex microbial disease involving various mechanisms that results in destruction of connective tissue and bone. Past understanding of etiology and pathogenesis of periodontal disease focused on the microbial aspect. Based on this the therapeutic efforts were focused on mechanical or chemotherapeutical removal of bacterial plaque. The plaque biofilm though considered the prime etiologic factor; it has been just associated with the initiation of disease.

Recent investigations have recognized the crucial role played by host responses involved in the progression & severity of the disease. So therapeutic efforts now is focused on altering (modulating) the host responses. The recent treatment strategy lies in modifying the host responses which will also help in evading the other risk factors like environmental and genetic that can modify the periodontal disease susceptibility. Host Modulation therapy is emerging treatment concept in management of periodontal disease.

This poster focuses on the present concept of host modulation in comprehensive periodontal management.

PS 21. Rejuvenation in periodontics using traditional herbs Dr.E.Gayathri priyadharshini,Dr.Aravindh raaj, Dr.Raghu Raaman, Dept of Periodontics, IGIDS. Abstract

Ayurveda is a holistic system of traditional medicine native to the Indian subcontinent, now practiced in other parts of the world as a form of complementary medicine. Even though dentistry was not a specialized branch of Ayurveda, it is included in its Shalakya Tantra (system of surgery).

Traditional medicine can treat various infectious and chronic conditions. In Ayurveda, dental health (danta swasthya in Sanskrit) is held to be very individualistic, varying with each person’s constitution (prakriti), and climatic changes resulting from solar, lunar and planetary influences (kala-parinama). The body constitution is classified based on the predominance of one or more of the three doshas, vata, pitta and kapha. The dominance dosha in both the individual and nature determines health care in Ayurveda, including dental health. Research has shown that all kinds of chewing sticks, green tea, oil pulling etc., promotes anti-cavity action, reduces plaque, and has an antibacterial effect. Use of safe, quality products and practices should be ensured based on available evidence if traditional medicine is to be acknowledged as part of primary health care. Scientific validations of the Ayurveda dental health practices could justify their incorporation into modern dental care. This poster explains the importance of traditional medicines for various dental treatments.

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APJ.ABDUL KALAM, Fmr. President of India at CIDRF Faculty and Staff of CIDRF

Editor in Chief - Mrs. A.N.Uma, Asst.Prof., Anatomy, MGMCRI

Sanjeevita Organizers

Sri Balaji Vidyapeeth and Central Inter-Disciplinary Research Facility MGMCRI campus, Pondy-Cuddalore main road, Pillayarkuppam, Puducherry-607402.