BME 2021 Newsletter by Mudbug Media

DEPARTMENT OF

BIOMEDICAL ENGINEERING

SCHOOL OF SCIENCE AND ENGINEERING • BIOMEDICAL ENGINEERING NEWSLETTER • 2021

MESSAGE FROM THE CHAIR Everyone knows that this was a year like no other, and one we will not want to repeat. Laissez le bonne temps roulez, (let the good times roll) was not operational; however, with great effort our department has pulled through and prospered despite the hardships imposed by teaching and learning in extremely difficult conditions such as wearing masks in enormous ‘cone of silence’ temporary classrooms. Donald Gaver has served as the Biomedical Engineering Department Chair for the past fifteen years. His laboratory research aims to develop an understanding of the interrelationships between the mechanical and physicochemical behavior of biological systems with a primary focus on the investigations of the pulmonary system.

Vibrant students kept us focused on our mission, and in this newsletter, we illustrate a few of their successes as well as notable achievements of our faculty. I would be remiss if I didn’t state that this experience has reinforced the necessity of teamwork on all levels – and this is truly the success story of this era. So, as we return to a new normal, we will retain the lessons we’ve learned related to the importance of developing and supporting meaningful collaboration and commaradarie, because that is how Tulane’s Biomedical Engineering good times roll! Likely, due to biomedical scientific and public health advances we will soon be able to renew in-person visits. I encourage you to visit so that you can experience our special department. Vaccinations are a must, though we are confident that this message is well understood by the recipients of this newsletter. Even if you cannot visit, we hope to hear from you and would encourage you to be part of our team. Sincerely,

Donald Gaver Chair, Tulane Department of Biomedical Engineering

FACULTY RECOGNITION

Carolyn Bayer won the 2020 Rising Star Award, Women in Molecular Imaging Network from the World Molecular Imaging Society.

Kristin S. Miller was awarded the American Society of Mechanical Engineering Y.C. Fung Early Career Award for 2021 for outstanding contributions to the field of bioengineering.

RESEARCH Huda, K., Swan, K.F., Gambala, C.T, Pridjain, G.C., Bayer, C.L. Towards Transabdominal Functional Photoacoustic Imaging of the Placenta: Improvement in Imaging Depth Through Optimization of Light Delivery, Annals of Biomedical Engineering, (2021) DOI: 10.1007/s10439-021-02777-0. Abstract: Functional photoacoustic imaging of the placenta could provide an innovative tool to diagnose preeclampsia, monitor fetal growth restriction, and determine the developmental impacts of gestational diabetes. However, transabdominal photoacoustic imaging is limited in imaging depth due to the tissue’s scattering and absorption of light. The aim of this paper was to investigate the impact of geometry and wavelength on transabdominal light delivery. Our methods included the development of a multilayer model of the abdominal tissue and simulation of the light propagation using Monte Carlo methods. A bifurcated light source with varying incident angle of light, distance between light beams, and beam area was simulated to analyze the effect of light delivery geometry on the fluence distribution at depth. The impact of wavelength and the effects of variable thicknesses of adipose tissue and muscle were also studied. Our results showed that the beam area plays a major role in improving the delivery of light to deep tissue, in comparison to light incidence angle or distance between the bifurcated fibers. Longer wavelengths, with incident fluence at the maximum permissible exposure limit, also increases fluence within deeper tissue. We validated our simulations using a commercially available light delivery system and ex vivo human placental tissue. Additionally, we compared our optimized light delivery to a commercially available light delivery system and conclude that our optimized geometry could improve imaging depth more than 1.6×, bringing the imaging depth to within the needed range for transabdominal imaging of the human placenta.

Geometry of commercial light delivery design, (b) Geometry of optimized light delivery design. (c) Plot of total fluence of commercial and optimized light delivery versus imaging depth for single layer of placenta at 808 nm. (d) Plot of total fluence of commercial and optimized light delivery versus imaging depth for multilayer tissue at 808 nm. The black dashed line indicates the threshold fluence value necessary to generate photoacoustic signal. The corresponding imaging depth for commercial and optimized light delivery system is indicated with green dashed lines (1.3 cm and 2.16 cm respectively). The shading in the plot (d) from left to right represents water and the layers of skin, subcutaneous adipose tissue, abdominal muscle and placenta respectively.

Mark J. Mondrinos, Farid Alisafaei, Alex Y. Yi, Hossein Ahmadzadeh, Insu Lee, Cassidy Blundell, Jeongyun Seo, Matthew Osborn, Tae-Joon Jeon, Sun MinKim, Vivek B.Shenoy, Dongeun Huh Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue, Science Advances, 12 Mar 2021: Vol. 7, no. 11, eabe9446DOI: 10.1126/sciadv.abe9446 Abstract: Here, we present an approach to model and adapt the mechanical regulation of morphogenesis that uses contractile cells as sculptors of engineered tissue anisotropy in vitro. Our method uses heterobifunctional cross-linkers to create mechanical boundary constraints that guide surface-directed sculpting of cell-laden extracellular matrix hydrogel constructs. Using this approach, we engineered linearly aligned tissues with structural and mechanical anisotropy. A multiscale in silico model of the sculpting process was developed to reveal that cell contractility increases as a function of principal stress polarization in anisotropic tissues. We also show that the anisotropic biophysical microenvironment of linearly aligned tissues potentiates Muscle soluble factor-mediated tenogenic and myogenic differentiation A549 Tumor of mesenchymal stem cells. The application of our method is Macrophage spheroid demonstrated by (i) skeletal muscle arrays to screen therapeutic modulators of acute oxidative injury and (ii) a 3D microphysiological model of lung cancer cachexia to study inflammatory and oxidative muscle injury induced by tumor-derived signals.

Lung fibroblast

ECM

RESEARCH D.P. Gaver, G.F. Nieman, L.A. Gatto, M. Cereda, N.M. Habashi, and J.H.T. Bates. The POOR Get POORer: A Hypothesis for the Pathogenesis of Ventilator-Induced Lung Injury. American Journal of Respiratory and Critical Care Medicine. 202: 1081-1087, 2020. Protective ventilation strategies for the injured lung currently revolve around the use of low VT, ostensibly to avoid volutrauma, together with positive end-expiratory pressure to increase the fraction of open lung and reduce atelectrauma. Protective ventilation is currently applied in a one-size-fits-all manner, and although this practical approach has reduced acute respiratory distress syndrome deaths, mortality is still high and improvements are at a standstill. Furthermore, how to minimize ventilator-induced lung injury (VILI) for any given lung remains controversial and poorly understood. Here we present a hypothesis of VILI pathogenesis that potentially serves as a basis upon which minimally injurious ventilation strategies might be developed. This hypothesis is based on evidence demonstrating that VILI begins in isolated lung regions manifesting a Permeability-Originated Obstruction Response (POOR) in which alveolar leak leads to surfactant dysfunction and increases local tissue stresses. VILI progresses topographically outward from these regions in a POOR-getPOORer fashion unless steps are taken to interrupt it. We propose that interrupting the POOR-get-POORer progression of lung injury relies on two principles: 1) open the lung to minimize the presence of heterogeneity-induced stress concentrators that are focused around the regions of atelectasis, and 2) ventilate in a patient-dependent manner that minimizes the number of lung units that close during each expiration so that they are not forced to rerecruit during the subsequent inspiration. These principles appear to be borne out in both patient and animal studies in which expiration is terminated before derecruitment of lung units has enough time to occur. The hypothesis of the pathologic tetrad of acute respiratory distress syndrome (ARDS) at the micro-scale. (A) Systemic or local inflammation causes an increase in permeability (endothelial leakage), which leads to (B) alveolar flooding with edema fluid (alveolar edema) inhibiting surfactant function (surfactant deactivation). (C) Alveolar edema causes a heterogeneous challenge generating stress-concentrators (Green Arrow) on neighboring alveoli. Loss of surfactant function destabilizes alveoli in this region, (D) predisposing them to cyclic recruitment and derecruitment (R/D) that initiates and exacerbates damage due to atelectrauma and regionally decreases the compliance.

KRISTIN S. MILLER GRANT: Predictive Modeling of COVID-19 Progression in Older Patients, National Institutes of Health, Award Number: GM103629 AWARD: $379,884.00 over 1 year FOCUS: The major goal of this project is to show that a mathematical model informed by key patient-specific suites of cytokines is capable of predicting patient trajectories, which will provide a strong evidence-based proof of concept for future efforts to rationally design interventions for severe COVID-19 patients.

MARK MONDRINOS AWARD: $35,000 in funding through the Tulane Center for Excellence in Sex-based Biology and Medicine (TCESBM) FOCUS: This project will focus on developing female and male microphysiological models of human airways for studying sex-based differences in the response to viral infections.

ALUMNI Trivia Frazier

Co-Founder, President, and CEO of Obatala Sciences, Inc. Q: What is your educational history? Dillard University Physics 2007, Tulane University BME 2008, TU SOM Biomedical Sciences PhD. 2012, and A.B. Freeman’s Executive MBA program in 2018. Q: What are some of your memorable experiences while at Tulane? As a 3-2 dual degree student, I started my undergrad coursework as an incoming junior in the BME program. This was quite a challenge! One of my memorable experiences was during the summer semester of 2005, before Hurricane Katrina. This was my first semester at Tulane, and I took Dr. Katherine Raymond’s Statics course. She was the first female engineering professor that I had, and I loved the way she taught the material and how approachable she was. This was impactful, because I felt like I wouldn’t fit in as the only African American and female student in the class! Other memorable experiences were working in Dr. Brian Rowan’s laboratory and matriculating through the BMS program. I interacted with people from all over the world and had the opportunity to learn about cultural differences and how the fundamentals of science cross all barriers. Q: What research did you conduct, and did it have any bearing on your career choice? As an undergraduate in the BME program I was introduced to stem cell research. I worked on a project that investigated the impact of bone marrow-derived stromal/stem cells on the growth of Osteosarcoma, a bone cancer that is of mesenchymal origin. After observing the impact of the stem cells on tumor growth and metastasis, we investigated the role of curcumin (turmeric) as an antioxidant and anticancer agent on the pathology in vivo. We used miniature osmotic pumps to deliver the curcumin, in the form of liposomes, directly into the tumor. That was the first time that I learned about applying engineering principles to a biological problem that interested me. It was also the beginning of my career as a stem cell researcher, and we now manufacture stromal/stem cells from adipose tissue and combine them with biological matrices to engineer tissue models for drug discovery.

Q: What did you do after graduating from Tulane? I pursued the traditional academic route, first as a postdoctoral fellow working in the lab of Dr. Jeffrey Gimble, in the Department of Adipose Biology at Pennington Biomedical Research Center (PBRC) in Baton Rouge. The lab relocated to New Orleans, so I ended up back in NOLA, working as a joint postdoc for Dr. Gimble and Dr. Bruce Bunnell, within the Tulane Center for Stem Cell Research and Regenerative Medicine. I went on to pursue tenure as an Assistant Professor at Delgado Community College (Chemistry) and then at Dillard University (Physics). I was promoted to Physics Program Chair at Dillard, before deciding to leave academia to work as a Project Director at LaCell, our parent company. This was one of the greatest decisions I made in my professional career, as it led to the spin out and founding of Obatala Sciences. Q: What has your career path been? My career path has been full of calculated risks and a pursued passion for learning. I started out academic in focus and was fortunate to have exposure to both the teaching and the administrative side of academia. Then I switched to biotechnology and worked as middle management and now in the executive capacity. Q: What advice do you have for undergrads? I wish I listened to my grandmother, who told me not to take life so seriously! As an undergraduate I was very determined to complete my degree requirements on time. During Hurricane Katrina, I decided to sit out a semester to help my parents rebuild our home. This meant that if I was going to complete the dual degree program on time, I had to work overtime...and I did. This led to a lot of unnecessary stress that I regret. Whether I completed my degree in 2008 or 2009, I still would have been proud of myself. It has taken a number of years to recover medically from the consequences of that decision. I realize that motivation is healthy, but too much stress is not! My advice is to take life with stride. Work hard but enjoy life. I have lost friends and family at a young age, partly because of stress. No accomplishments in life are worth losing your life. This is particularly important during times like these, when we are searching for ways to remain connected to people during a pandemic. Mental health is just as important as physical health. Q: What is your advice for those who want to follow your path? Soak up knowledge from those around you, and don’t be SPOTLIGHT continued on next page 4

ALUMNI SPOTLIGHT continued from previous page afraid to reach out to someone who is a leader in your field or has taken the path that you would like to take. You’d be surprised who you already know, and who is willing to have a conversation with you! One of my most important lessons was to learn to network and to leverage my existing network. This isn’t something that was commonly discussed as a scientist, but it was reinforced in business school, and I appreciate it. Q: What is the first thing you think about when you think about Tulane? Opportunity. That word comes with a heavy meaning. For many students that means a set of circumstances may arise that will provide you with a set of experiences that can change your entire life for the better.

someone will be willing to care about them and their goals, to support them and to mentor them, in the same capacity as other students. I think about those experiences, those people who took the chance on me as an undergrad and graduate student, and how I can do the same for someone else. Q: How have you stayed in contact with Tulane? I remain in contact with several my former professors and advisors in all of the school programs, and I’ve been fortunate enough to not only collaborate with some of them on research projects, but also to hire students that have trained with them since my matriculation through the programs. This has been a very rewarding part of my relationship with Tulane.

For many African American students, it means that

INNOVATION

ReSuture, a company founded by Tulane biomedical engineering graduates, Hannah Eherenfeldt and Benjamin Knapp, has won a National Science Foundation (NSF) Small Business Research (SBIR) award. Learn more at: Tulane graduates’ medical simulation startup receives prestigious NSF award.

BioAesthetics was awarded a $250,000 grant by the NSF to develop a product for treating bed sores or pressure ulcers. The product will be tested at Tulane University. The company was founded by Nick Pashos, a Bioinnovation graduate, and the COO, Billy Heim, who received his undergraduate degree from Tulane biomedical engineering. Pictured Billy Heim and Nick Pashos Learn more at: BioAesthetics and Tulane awarded grant to develop new advanced wound-care graft.

AxoSim, a company began in Dr. Michael Moore’s laboratory has received investment funds from Benson Capital Partners, founded by Gayle Benson, owner of the New Orleans Saints. AxoSim’s BrainSim and NerveSim platforms allow the testing of potential new drugs in the laboratory by using stem cells to mimic the structure and function of the human nervous system and brain. AxoSim is led by CEO Lowry Curley, PhD and Chief Business Officer Ben Cappiello, both graduates of Tulane Biomedical Engineering. 5

AWARDS Yuntong Bai, a PhD student in Dr. Yu-Ping Wang’s Multiscale Bioimaging and Bioinformatics Laboratory won two awards at the 2020 SPIE medical imaging conference in Houston, TX. Yuntong was a Robert F. Wagner Best Student Paper Award Finalist for a paper entitled “An Imaging epigenetics study of Schizophrenia with structure-enforced collaborative regression” and won an honorable mention award for a poster entitled “Integration of multi-task fMRI for cognitive study by structure-enforced collaborative regression”. Abstract: In the study of complex mental disorders like schizophrenia (SZ), while imaging genetics has achieved great success, imaging epigenetics is attracting increasing attention as it considers the impact of environmental factors on gene expression and resulting phenotypic changes. In this study, we proposed a novel structure-enforced collaborative regression model (SCoRe) to extract co-expressed discriminative features related to SZ from fMRI and DNA methylation data. SCoRe can utilize phenotypical information while enforce an agreement between multiple data views while also considers the group structure within each view of data. The brain network based on fMRI data can be divided into 116 regions of interests (ROIs) based on anatomical structures of the brain and the DNA methylation data can be grouped based on pathway information, which are used as prior knowledge to be incorporated into the learning model. We applied the model to data of 184 participants (104 SZ and 80 healthy subjects) collected by MIND Clinical Imaging Consortium (MCIC); we succeeded in identifying 8 important brain regions and 3 genes associated with SZ. This study can shed light on the understanding of SZ from both brain imaging and epigenomics, complementary to imaging genomics. SCoRe_MCIC: The flowchart of applying structure-enforced collaborative regression model (SCoRe) to jointly analyze DNA methylation and fMRI data from the MIND Clinical Imaging Consortium: import training data (including DNA methylation, and Auditory Oddball task fMRI), corresponding grouping structures (biological pathways for DNA methylation data and Automated Anatomical Labeling template for fMRI) and observation (Schizophrenia phenotype) into the SCoRe model to select important features. The identified features are then validated on the testing group. \gamma^*, \lambda_1^* and \lambda_2^* are optimal hyper-parameters that are determined by a non-nested crossvalidation.

Kali Dancisak, Carly Harad, Ava Heller and Marjie Williams won first place at the Southeast Louisiana Veterans Health Care System Performance Excellence Fair for their project, Socket To Me, a design that improves the manufacturing of lower limb prosthetic sockets. Learn more at Tulane engineering students place first in design competition. Rachel Tabor, a junior in biomedical engineering, won the 2021 WE Local Rising Star Award (Future Collegiate Leader). The award is for those that have made “outstanding contributions to SWE, the engineering community, their campus, and the community.” 6

DESIGN Student Team Design Every year seniors in the Tulane School of Science and Engineering present their final projects at the Engineering Capstone Design Expo. The expo took place virtually this year on April 21, 2021. Information on all of the projects may be found at 2021 Engineering Capstone Design Expo. Cerfix, composed of Emma Chapel, Katherine Mattingly, Sydney Siegmeister, and Madeline Tallman, was the Overall Winner – Biomedical Engineering at the 2021 Engineering Capstone Design Expo. Cerfix is developing an all-in-one device that will apply acetic acid, illuminate, and capture an image of the cervix and contains its own opening mechanism. The device is designed to be used in low resource areas such as Peru where barriers to cervical cancer screening include a lack of trained cytologists, a fear surrounding the screening process, and poor record-keeping and patient follow up. Cerfix was also a semi-finalist in the 11th Annual Undergraduate Global Health Technologies Design Competition at Rice University. Accuream, composed of Ana Figel, Matthew Weintraub, Charles Dranoff, and Jillian Baggett, was the Audience Favorite – Biomedical Engineering at the 2021 Engineering Capstone Design Expo. During total hip arthroplasties, an orthopedic surgeon uses a reamer to cut through the cortical layer of the bone and scratch the cancellous layer to cause bone bleeding which aids in patient recovery. Accuream is developing a device to help quantify the amount of force, heat, and usage of each reamer blade in order to prevent surgical complications.

Teams Accuream (L) and Cerfix (R) receiving their certificates from Drs. Don Gaver and Katherine Raymond at the BME Annual Awards banquet.

Solid Works simulation of the stress distribution on the petals of the Cerfix device.

Accuream’s device seamlessly integrates with existing reamers to monitor force and temperature data.

Since winning the 2020 Design Expo, Trach Tech has completed two I-Corps Site programs, one with LSU and one with the University of Washington. Each included $2000 towards customer discovery efforts such as conferences and trade shows. They have completed the VentureWell E-Teams Stage 1 grant for $5,000 and applied for a stage 2 grant worth $20,000. Trach Tech was a finalist for the 2021 Tulane Novel Tech Challenge which gained them several valuable mentors as well $1,000 dollars in funding for design advancement. Future plans include working with Dr. Chrissy Guidry at TUMC where they will test the effectiveness of their device on removing mucus and bacteria from tracheal tubes. 7

PEOPLE Undergraduate Student Focus: MARY MAY YOON PWINT Hometown: Yangon, Myanmar • Graduation: May 2021 Favorite Class: Biomedical Signals and Systems with Dr. J. Quincy Brown. The class teaches intuitive thinking for analyzing signals and systems which helped Mary piece together techniques, concepts, and jargons that previously seemed disconnected. Undergraduate Research: Mary is doing her thesis research in Dr. Miller’s lab on computational modeling of lung damage caused by COVID-19. This is an interdisciplinary research project which allows the application of classroom knowledge in biology, engineering, math, and computer science. Tulane Accomplishments: Mary was the winner of the Cronvich Award, which is awarded for outstanding achievement in biomedical engineering studies. She was also presented with a Biomedical Engineering Senior Scholar Award for an outstanding senior thesis. In addition to these Mary won the Computer Science Capstone Design Expo Award. Outside the Lab: Mary spends her free time participating in badminton and karate. She has a black belt in Shotokan Karate. She also enjoys cooking, baking, and reading random science articles. Post-Graduation: Mary is planning to attend graduate school.

Master’s Student Focus: MAX WENDELL Hometown: Baltimore, Maryland Undergraduate Degree: Biomedical Engineering, Tulane University, New Orleans, LA Research Lab: Mark Mondrinos’s Tissue Engineering Microphysiological Systems (TEMPS) Laboratory. Research Focus: Engineering a comprehensive organ on a chip model to study fibrotic disease. The most exciting aspect of this research is the impact it could have for others developing organ chip models for cancer and other fatal diseases. Post-Graduation: Working as a research associate at Emulate, an organ chip company in Boston, Massachusetts. Outside the Lab: Max loves traveling and spent the summer of 2019 in Barcelona working on a start-up health app and travelling around Europe. He loves to fish, especially with his dad, and they fish together in competitive tournaments. He also likes cooking new recipes with friends. Favorite Things in New Orleans: While Max loves the music and weather, the food, especially crawfish and po-boys, is his favorite. Interesting Fact: Max worked with Walter Issacson and reviewed drafts of his new book “The Code Breaker” which follows Jennifer Doudna and the advent of CRISPR.

PEOPLE Bioinnovation Student Focus: MARYL WRIGHT Hometown: New Orleans, Louisiana Undergraduate Degree: Biological Sciences, University of New Orleans, New Orleans, Louisiana. Research Lab: Burow/Collins-Burow Laboratory, Tulane University School of Medicine Research Focus: Developing and utilizing a decellularized tumor matrix model to define the mechanisms of kinase signaling on triple negative breast cancer invasion and metastasis. Grants: NIH Research Supplement to Promote Diversity in Health-Related Research, CCTS Predoctoral Clinical/Translational Research (TL1) Traineeship. Post-Graduation: Post-doctoral studies while developing a cancer drug screening tool that will be used by drug companies and researchers. Outside the Lab: Maryl has three children, ages 11, 8, and 5. Balancing family and graduate school is challenging, but it is rewarding and worth it! Maryl also volunteers, along with others from her lab, with Krewe de Pink, a local breast cancer survivor organization. Krewe de Pink raises money the Tulane Cancer Center to help fund breast cancer research. Maryl enjoys attending their fundraising events, such as the Pink Bra Run and Pink Prom.

Graduate Student Focus: DYLAN LAWRENCE Hometown: Shamokin, PA Undergraduate Degree: Biomedical Engineering at Widener University, Chester, PA Research Lab: Carolyn Bayer’s Biomedical Functional Imaging Laboratory. Research Focus: Developing noninvasive imaging tools that will improve the understanding of pregnancy-related diseases. This is an understudied field without enough data to support the development of new treatment options. The novel imagining techniques Dylan is working on provide a preclinical foundation for new medical applications that can improve maternal and fetal health. Post-Graduation: Imaging Applications Scientist at PhotoSound Technologies, Inc. in Houston, Texas. Outside the Lab: Dylan enjoys spending time with his family, especially his husband and their dog Max. He likes to cook (his parents owned an Italian restaurant growing up, so he makes lots of Italian food, but Cajun is his favorite), and also woodworking in his free time. Favorite Things in New Orleans: Everything – the culture, the food, the festivals, and the people. This city will always be incredibly special to Dylan due to so many wonderful memories made here.

PEOPLE Tulane Biomedical Engineering Class of 2021

Tulane 34 Award

Biomedical engineering students Jillian Baggert, Stephen Hahn, Tia Monjure and Matthew Weuntraub were honored with the 2021 Tulane 34 award. The Tulane 34 Award is presented to 34 graduates who have distinguished themselves throughout their collegiate life at Tulane.

Grand Challenges Scholars The 2021 Cohort of the NAE Grand Challenges Scholars Program (GCSP) included four biomedical engineering students: Miguel Brache, Liz Bryan, Carly Harad and Lydia Trautmann along with physics and engineering physics student Katie Cartiglia. They presented their final showcase over Zoom on April 26, 2021. Click here to learn more and watch the presentations.

2021 Grand Challenges Scholars: Miguel Brache, Lydia Trautmann, Katie Cartiglia, Liz Bryan, Carly Harad.

KEEP IN TOUCH WITH US!

William Wallace Peery Society

Mailing Address: Department of Biomedical Engineering Lindy Boggs Center Suite 500 Tulane University New Orleans, LA 70118

Carly Harad was one of twenty graduating seniors inducted into NewcombTulane College’s William Wallace Peery Society, the university’s top academic honor.

Commencement Speaker Dylan Lucia was selected as a speaker at the 2021 graduation ceremonies, where he received his master’s degree in biomedical engineering.

Phone: 504-865-5897 Tulane BME Website: sse.tulane.edu/bme LinkedIn: www.linkedin.com/groups/1923837/ Facebook: www.facebook.com/groups/TulaneBME/ 10