International Journal of Translational Medical Research and Public Health Volume 1 Number 2

IJTMRPH

ISSN: 2576-9499 (Online) ISSN: 2576-9502 (Print) www.ijtmrph.org

Vol 1 No 2 (2017) Research · Translate · Save Lives

INTERNATIONAL JOURNAL of TRANSLATIONAL MEDICAL RESEARCH and PUBLIC HEALTH Int. J. Trans Med Res Pub Hlth

A Journal of the Global Health and Education Projects, Inc.

THERAPEUTIC EFFICACY OF ARTEMETHER-LUMEFANTRINE IN SUBCLINICAL MALARIA IN SOUTHEASTERN NIGERIA Precious Okechukwu Eteike, MBBS | Evangeline Tochi Oparaocha, PhD

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Introduction: To combat the growing Title and Content Layout with List resistance to antimalarial drugs, assessment of antimalarial drug efficacy is necessary for monitoring and containment. The objective of the study was to assess the therapeutic • Add your first bullet point here efficacy of antimalarial drug, Artemether-Lumefantrine (AL) in subclinical • Add your second bullet point here malaria.

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Method: This was a community--based interventional (therapeutic) study conducted in two communities: Naze and Ikenegbu, both in Imo State of South Eastern Nigeria. The study population consisted of two groups (subclinical and clinical), males and females aged 18 years and above, who fulfilled the inclusion criteria. A systematic house-to-house sampling technique was employed to select a total of 117 and 66 participants for the subclinical and clinical groups respectively. Ninety-three of the 117 and 65 of the 66 participants in the subclinical and clinical groups respectively were successfully followed up to Days 3 and 7 of the treatment.

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Results: On days 3 and 7, the Parasite Clearance Rates were 86% and 87.1% for the subclinical group and 67.7% and 78.5% for the clinical group.

When the parasite clearance rates of the two groups were compared, and analyzed for the two treatment days, the result showed a significant (P<0.05) higher parasite clearance rate among the subclinical group on the Day 3, over the clinical, but a relative difference (P>0.05) between the two groups on Day7.

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Conclusion and Implications for Translation: Treatment of malaria with Artemether-Lumefantrine provides a better outcome at the subclinical stage than at the clinical stage. Further studies are needed to rule out imminent Artemether-Lumefantrine resistance in the study areas.

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Key words: Malaria • Therapeutic Efficacy • ArtemetherLumefantrine • Subclinical Malaria • Southeast Nigeria

Vol 1 No 2 (2017), Published: 2017-09-12; DOI: https://doi.org/10.21106/ijtm

SELF-REPORTED OCCUPATIONAL STRESS, ENVIRONMENT, WORKING CONDITIONS ON PRODUCTIVITY AND ORGANIZATIONAL IMPACT AMONG NURSING STAFF IN NIGERIAN HOSPITALS PhD | Olayinka A. Onasoga, RN, MSc | Christianah Olayemi Babalola, RN

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Title and Content Layout withstress List and burnout are both one of the Background: Occupational factors that bedevil the healthcare sector in developing countries, particularly in Nigeria. The study explored the perceived impact of • Add your first bullet point here working condition on the productivity of nursing staffs in selected • Add your second bullet point here hospitals in south-west Nigeria.

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Methodology: Descriptive survey design, comprising of 200 respondents selected randomly. Data were collected using questionnaires and descriptive statistics were used to analyze the data generated. The reliability of the instrument was determined using testre-test at the interval of two weeks.

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Results: Majority 106 (53%) of the respondents reported that work stress caused increased rate of absenteeism among nurses, high staff turnout and deterioration in quality of service provided to patients.

Majority (87.0%) of the respondents were females, while (13.0%) were males. Respondents were aged between 26 and 35 years and were married. About 79% of respondents agreed that their workplace had a warm, friendly and a pleasant atmosphere. However, 47.5% of respondents said that the work overload was too high and they were unable to cope with its demands.

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Conclusion and Implication for Translation: Stress arising from poor working conditions can have adverse impact on the organization with the most common detrimental effects being increased absenteeism, deterioration in the morale of nurses, lack of job satisfaction and performance. To improve the organization’s effectiveness, employer must implement strategies that are beneficial to both employees and health organization because hospital workers face variety of highly stressful working conditions while meeting the physical and psychological needs of patients.

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Key words: Perception • Working conditions • Nursing staff • Productivity • Hospitals, South-West • Nigeria Vol 1 No 2 (2017), Published: 2017-09-27; DOI: https://doi.org/10.21106/ijtm

KNOWLEDGE AND PRECONCEPTION CARE SEEKING PRACTICES AMONG REPRODUCTIVE-AGE DIABETIC WOMEN IN ZAMBIA Patricia Mutale | Mwenya Kwangu, MSc | Chishala Mirriam Kapambwe Muchemwa, MSc | Moono Silitongo, MSc | Mutale Chileshe, PhD | Seter Siziya, PhD

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Title and Content Layout withPre-existing List Background and Objectives: diabetes is associated with poor pregnancy outcomes, yet much is unknown about knowledge of preconception care among diabetic women. The objective of this study was to • Add your first bullet point here examine the knowledge and preconception care seeking practices of diabetic • Add your second bullet point here women in the reproductive age.

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Methods: A cross- sectional hospital based study of 114 diabetic women between 15-45 years old was conducted between March and May 2017. Data was collected using structured questionnaires in face to face interviews. Chisquare test was used to determine the association between knowledge levels and identified factors; these were further analyzed using binary logistic regression to determine the adjusted odds of poor knowledge.

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Results: The findings showed that 52.6% of diabetic women that participated in our study had poor knowledge of preconception care. Independent factors associated with poor knowledge on preconception care were up to primary level of education [AOR 4.54, 95% CI (2.23, 9.27)] and ?1 year duration of diabetes diagnosis [AOR 3.21 95% (1.35, 7.65)]. About 67% of the participants with a history of being pregnant after diagnosis of diabetes did not seek pre-conception care.

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Conclusions and Implications for Translation: The study indicated poor knowledge level as well as poor practice of seeking preconception care.

There is need to explore the establishment of clinical guidelines and policies that will allow the dissemination of pregnancy related advise to diabetic women.

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Key words: • Diabetes Mellitus • Diabetic Women. • Preconception Care • Reproductive Age Group • Knowledge • Practice • Zambia

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Vol 1 No 2 (2017), Published: 2017-11-23; DOI: https://doi.org/10.21106/ijtm

International Journal of Translational Medical Research and Public Health Journal Information Editor-in-Chief: Romuladus E. Azuine, DrPH, MPH, RN.

Title and Content Layout with List Editor: Gopal K. Singh, PhD •

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Editorial Assistant: Carl Dowling, SAP.

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Contact Information: submissions@ijtmrph.org

Website: www.i tmrph.org