Nanoparticles Assisted Laser Desorption/Ionization Mass Spectrometry Hani Nasser Abdelhamid Department of Chemistry, Assuit University, Assuit, 71515, Egypt E-mail: hany.abdelhameed@science.au.edu.eg
Abstract Application of nanoparticles for mass spectrometry open new venues for many fields such as medicine, biotechnology, proteomics, analytical chemistry, …etc. It offered many advantages such as high sensitivity, selectivity, no ion suppression, high ionizability, multifunctionality, stable under vacuum, and offer high adsorption capability. The unique properties of nanoparticles is promising for leading the future.
Figure 1. The difference among a) organic matrix, b) ionic liquid and c) nanoparticles
High Sensitivity
Figure 2. Schematic representation of the nanoparticles applications for mass spectrometry included separation, analysis using other spectroscopy and mass spectrometry imaging.
Past
Multifunctionality
Present
Future
Selectivity Organic Matrix
Advantages of NPs High Ionization
No Ion Suppression
Stable Under Vacuum
No Interferences
Ionic Liquid
Nanoparticles
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