Neoalgae, as a reference research center in the cultive of microalgae, has been certified in the FSSC 22000 standar
This certification offers a series of benefits for Neoalgae. For example, the FSSC 22000 standard guarantees that the company meets the necessary standards to safeguard the public health and ensure food safety or to be able to expand to other markets by meeting the required international food safety standards. It also provides confidence to clients by having a certification of these characteristics and provides recognition and acceptance by suppliers or potential client companies.
INNOVATION
Neoalgae is certified as technological SME from the Ministry of Cience and Innovation of the Spanish government
microalgae and microalgae extracts
Neoalgae labs has positioned itself as a b cultivation and development of microalgae with a strong environmental commitment It is a pioneer in the development of microalgae applications and cultures, as well as placing innovative references on the market through its different brands and business lines. It has its operational headquarters in a modern, energy self-sufficient plant in Gijón, comprising greenhouses for the cultivation of different species of microalgae, specialised laboratories, a natural cosmetics manufacturing plant and a recently inaugurated office building that has increased the plant’s technical capacity. It also has 9 patents, 12 awards, 18 certifications and nearly 40 R&D projects, and is certified in FSSC 22,000
OUR PATENT
neoXENSE
MICROENCAPSULATION TECHNOLOGY
The main active compounds of microalgae are found in their oily extracts
These oleoresins are rich in carotenoids, but they oxidize very quickly Neoalgae has developed a patented natural encapsulation method that allows preserving and amplifying the properties of these oleoresins, using spirulina as the protection tool
The microencapsulation oil process in Spiruline is the result of internal developments at NEOALGAE, and has been patented in Spain (ES 2 728 088 B2), EU (EP20382612.8) and USA (US-2022-0007898- A1)
Main benefits:
Spiruline increases the antioxidant properties, providing more benefits to the final product.
The stability and conservation and the final product is increased
The final product is powder (i.e. astaxanthin microencapsulated in Spiruline), not oil
Astaxanthin encapsulated in Spiruline (APAsta) has a clearly higher antioxidant capacity (CEAC) than Astaxanthin alone (ASTA) and hardly decreases over time, unlike ASTA, which suffers a marked decrease along the months
Studies carried out at Bioquochem Laboratories (Spain, 2024)
ASTAXENSE
ASTAXENSE
Microalgae Spirulina and Haematococcus pluvialis oil
Astaxense is a nutraceutical compound in powder format composed of free astaxanthin and spirulina.
This format allows the antioxidant capacities of the product to be stably preserved for longer if you compare it directly with astaxanthin oil or the biomass of the microalgae Haematococcus pluvialis.
The concentrations of free astaxanthin can range from 15 mg to 18 mg per daily dose, depending on the type of capsule used per product.
Astaxense can be used directly as a single product or used as an ingredient in a multivitamin form since it complements well with other types of vitamins or natural compounds.
Astaxanthin is the best known and studied natural ingredient in the world of microalgae. To date, there are more than 3,000 scientific articles published, demonstrating its healthy properties in multiple aspects of human health
Astaxense is made under a Neoalgae patent where the oleoresin rich in astaxanthin, which is difficult to incorporate into the final product, is transformed into an easily assimilated powder.
Powder
1Kg opaque bag
MOQ: 2Kg
Bibliography
Bioactivities of astaxanthin from natural sources, augmenting its biomedical potential: A review
P.A. Aneesh et al.
Trends in Food Science & Technology (2022)
Astaxanthin, has been proven to be extremely beneficial in working against several diseases like hypertension, diabetes and cancer Its antioxidant properties are used to combat oxidative damage in diseased cells The powerful bioactive antioxidant property of this nutraceutical and its beneficial role in protecting cells, tissues and organs from oxidative damage are well established Astaxanthin produced synthetically shows lower biological activity than naturally produced one
K Chan et al
Astaxanthin attenuated thrombotic risk factors in type 2 diabetic patients
Journal of Functional Foods (2019)
In this study, the intervention of AX in type 2 diabetic patients markedly improved lipid profiles, reduced inflammatory cytokines and attenuated hemostatic disorders These findings imply that the supplement of astaxanthin or foods rich in this functional compound is helpful for the prevention or alleviation of diabetic coagulatory disorders
C Farruggia et al
Astaxanthin exerts anti-inflammatory and antioxidant effects in macrophages in NRF2dependent and independent manners
Journal of Nutritional Biochemistry (2018)
Chronic inflammation and oxidative stress contribute to the pathogenesis of obesity-associated chronic diseases Macrophages generate ROS that trigger oxidative stress and inflammation, which are critical underlying causes of chronic diseases In macrophages, while NFκB induced the production of pro-inflammatory mediators, NRF2 counteracts NFκB by enhancing endogenous antioxidant defense. Studies have shown anti-inflammatory properties of Astaxanthin in macrophages Consistently, we found that mRNA levels of Il-6 and Il-1β were significantly decreased by Astaxanthin with no changes in Tnfα mRNA when RAW 264.7 macrophages were stimulated with LPS for 3 h (Fig. 1A). Our time-course experiment demonstrated that the induction of Il-6 and Il-1β expression by LPS reached the maximal levels at 12 h of LPS stimulation, and ASTX significantly decreased the pro-inflammatory gene.
Dietary astaxanthin: an excellent carotenoid with multiple health benefits
Yunrui Cao,Lu Yang,Xing Qiao,Changhu Xue &Jie Xu
Pages 3019-3045 | Published online: 28 Sep 2021
Recent studies have increased our understanding of the role of isomerization and esterification in the structure–function relationship of dietary astaxanthin Gut microbiota may involve the fate of astaxanthin during digestion and absorption; thus, further knowledge is needed to establish accurate recommendations for dietary intake of both healthy and special populations Associated with the regulation of redox balance and multiple biological mechanisms, astaxanthin is proposed to affect oxidative stress, inflammation, cell death, and lipid metabolism in humans, thus exerting benefits for skin condition, eye health, cardiovascular system, neurological function, exercise performance, and immune response Additionally, preclinical trials predict its potential effects such as intestinal flora regulation and anti-diabetic activity Therefore, astaxanthin is worthy of further investigation for boosting human health, and wide applications in the food industry
OMEGAXENSE
OMEGAXENSE
Spirulina and Schizochytrium sp. oil
Product composed of spiruline powder, enriched with omega 3 DHA from the microalgae Schizochytrium sp.
Omega 3 fatty acids are a type of polyunsaturated fatty acids that are essential to maintain a good physiological state
Our body cannot produce this type of fatty acids and we incorporate them into the diet since they are present in many of the fish we consume, which do not synthesize them either but simply accumulate them by consuming the phytoplankton present in the sea
Our OmegaXense goes directly to the source and uses an oil rich in Omega 3 from a microalgae (Schyzocitrium) which is microencapsulated under neoalgae's own patent, transforming and protecting the degradation of the oil and obtaining a nutraceutical powder ingredient, which format tis easily Incorporable in any nutraceutical formulation that wants to incorporate essential fatty acids
Without fish aroma, powder format and CDR ranging from 40 mg to 140 mg daily dose per capsule depending of the size.
Powder
1Kg opaque bag MOQ: 2kg
FT-04-78
Bibliography
EPA (Nannochloropsis) and DHA (Schizochytrium) from microalgae oils in Wistar rats
Taken together, the combination of EPA and DHA from Schyzo oil can counteract the undesirable health effects of saturated fat based diets and benefit, in the long run, neurological function
DHA intake may be associated with several health endpoints ranging from inflammatory processes, asthma and rheumatoid arthritis to CVD and diabetes mellitus as well as to depression and cancer. Particularly, DHA has an important role in the nervous system, which is highlighted by its prominence in neural tissues.
3.Electroencephalographic study of microalgae DHA omega-3 egg consumption on cognitive function
The influence of microalgae-DHA eggs (2 eggs/day) with additional >250 mg of DHA/day on the activity of the central nervous system in these young healthy subjects can be seen after 4–8 weeks of consumption indexed by the Go/NoGo task. The activation related to Go/NoGo tasks was recorded over frontal and temporal brain areas which plays important role in the regulation of intellectual function and action
FUCOXENSE
Arthrospira platensis
Microalgae Spirulina and Phaeodactylum tricornutum oil
Fucoxense is a product that contains Phaeodactylum tricornutum oil enriched in fucoxanthin, dl-α-tocopherol, and a spirulina powder matrix The composition of Fucoxense is approximately 49.4% Phaeodactylum tricornutum oil (enriched in fucoxanthin), 12% dl-α-tocopherol, and 494% spirulina powder The final product of Fucoxense contains 1.3-1.5% fucoxanthin, which is a type of carotenoid found in brown seaweed and other marine sources. Fucoxanthin has been studied for its potential health benefits, including antioxidant and antiinflammatory properties.
Spirulina is a microalgae with a high protein content, which has led WHO to consider it as the best food for the future. It has a high nutritional value because it is an important source of linoleic acid (omega 6 fatty acid), palmitic and oleic fatty acids, vitamins (A, B complex, E, biotin, folic acid, inositol), natural pigments, essential amino acids and minerals It is very rich in iron, an essential mineral for the body.
Fucoxanthin is a type of carotenoid, it is a xanthophyll, structurally similar to Beta Carotene and vitamin A. Despite its molecular structure, Fucoxanthin does not act as a vitamin itself, but rather contributes to enhancing the metabolic rate and the loss of fat. Fucoxanthin is such a special molecule that offers a wide range of bioactivities Results from animal studies have shown its potential value in the prevention and treatment of lifestyle-related diseases, such as obesity, diabetes or other chronic diseases.
1Kg opaque bag MOQ: 2Kg FT-04-47
Bibliography
Phaeodactylum tricornutum as Fucoxanthin Biofactory Model and Hepatoprotective Effect of Encapsulated Spirulina and Fucoxanthin
https://wwwmdpicom/2076-3417/13/13/7794
MTX (5 mg/mL) produced adequate hepatotoxic stress, and a decrease in cell viability of the human hepatocyte cell line was observed
The active ingredient (spirulina–fucoxanthin) showed hepatoprotective activity against the hepatotoxic compound MTX in the human hepatocyte cell line HEPG-2 at a concentration of 025 mg/mL
The current results also suggest that spirulina–fucoxanthin has beneficial properties for liver health and is a suitable ingredient for all types of natural functional foods
Phaeodactylum tricornutum as a stable platform for pilot scale production and investigation of the viability of spirulina fucoxanthin as a commercial lipolysis active novel compound
The availability of naturally occurring carotenoids in microalgae, such as fucoxanthin, provides an attractive source for the production of natural antioxidants. This, combined with the environmental and pollution control benefits of cultivating these microorganisms, makes them a potential asset to the global economy. In the present research, the culture of the Phaeodactylum tricornutum microalgae was successfully scale-up and the following points were concluded: Fucoxanthin content in P. tricornutum was shown to be higher at low light intensities, and also appears to be more stable during the scale-up. Cultivation under medium light intensity does not remain stable but reaches production values similar to the previous one (25 mg/day/L) The instability of this test was also affected by the extreme temperature conditions of the site, reaching 40 °C, which caused a decrease in production of 05 mg/day/L
The antioxidant capacity of fucoxanthin showed a significant decrease during the storage process However, although the fucoxanthin-rich product is reduced, the antioxidant capacity is maintained after 18 months Also, the antioxidant capacity of fucoxanthin encapsulated in spirulina was greater than that of the biomass Thus, the antioxidant capacity of encapsulated fucoxanthin-spirulina is therefore greater than that of spirulina alone This capacity is clearly due to the capabilities of fucoxanthin The fucoxanthinspirulina material incorporated in a fat burning cosmetic showed a high inhibitory effect on lipogenesis at all concentrations tested, as well as a remarkable lipolytic function, especially at 02 and 01 mg/mL
ASTAXENSE
OMEGAXENSE
NUTRACEUTICAL INGREDIENTS
INDICATIONS SUMMARY
FUCOXENSE
MICROALGAE
Spirulina - Arthrospira platensis
Green dehydrated powder composed exclusively of microalgae
Arthrospira platensis (Spirulina), unicellular organism that grows in brackish water (with a small percentage of salt).
Arthrospira platensis is an unicelular cianobacteria.
Powder
1Kg opaque bag
MOQ: 2Kg
FT-02-01
USES
1. Nutritional supplement: Spirulina is rich in protein, vitamins (such as B12 and A), minerals (such as iron and magnesium), and antioxidants
2 Improved physical performance: High protein and essential amino acid content.
3 Weight control: Helps to reduce appetite
4 Immune system booster: Thanks to its antioxidants, such as phycocyanin.
5 Detoxification
6 Improved digestive health
7 Cardiovascular health: Helps reduce cholesterol, blood pressure, and control blood sugar levels.
8 Skin and hair health.
Chlorella vulgaris
Green dehydrated powder composed exclusively of the microalgae Chlorella vulgaris, spherical unicellular organism that grows in fresh water.
Powder
1Kg opaque bag
MOQ: 2Kg
FT-02-02
1. Nutritional Supplement: It is rich in protein, vitamins (such as B12 and vitamin C), minerals (iron, magnesium) and antioxidants
2 Detoxification.
3. Immune System Support: Thanks to its content of antioxidants and other nutrients
4 Digestion Improvement: By containing chlorophyll and fiber.
5 Cholesterol and Blood Glucose Control.
6 Energy and General Well-Being.
7 Skin Care: Antioxidant and regenerative properties USES
Tetraselmis chuii
Dehydrated brown powder consisting exclusively of the microalgae Tetraselmis chuii.
Tetraselmis chuii is a green unicellular microalgae with flagella. It is grown in salt water.
Powder
1Kg opaque bag
MOQ: 2Kg
FT-03-01
1. Food Supplements: Rich in protein, omega-3 fatty acids, minerals and vitamins.
2. Cosmetics: The antioxidant and anti-inflammatory.
3. Aquaculture: High content of protein, essential fatty acids, vitamins and antioxidants.
