Advancing neuromodulation research
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NeuroNexus is the global leader in neuroscience research. Now expanding into clinical research. NeuroNexus is an official NIH BRAIN Initiative® partner.
Originally developed at the University of Michigan, NeuroNexus’ suite of commercialized technologies has, for over a decade, led to hundreds of publications from research labs all around the world. Our products include conventional and high-density leads, recording and stimulation systems, and software for data analytics. Our products have been used in a wide variety of animal models from fruit fly to rodent to non-human primates. NeuroNexus is currently working to make our state-of-the-art technologies and systems available for human clinical research.
Currently not available for sale
Next page, clockwise from top left: Matrix Array™, Vector Array™, SmartBox™, Quad-fiber Optoelectrode. See the NeuroNexus Research Product Catalog at neuronexus.com for more information.
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NeuroNexus is at the intersection of neuroscience, technology, and clinical drivers. Science drivers: NeuroNexus powers leading-edge neuroscience research around the world
Clinical drivers: NeuroNexus is uniquely positioned to translate new technologies into innovative neuromodulation systems
Technology drivers: NeuroNexus continually innovates neural interfaces to meet the needs of both scientific and clinical research
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Core Technologies and Competencies • High resolution thin-film technologies utilizing silicon and polymer materials • Draw from our design tools and libraries for advanced thin-film neural interfaces • Translation of leading-edge concepts into commercial solutions • Computational modeling and analysis of neural interface devices and systems • Rapid prototyping • Resources and expertise for testing and validation • Collaboration and networking with leaders in the clinical and neuroscience fields
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Custom Design NeuroNexus offers a custom lead design service that provides unique access to a virtually unlimited design space. Almost any feature of a lead can be tailored to suit your application - and all it takes to get started is a sketch. Each custom lead includes: • Consultation with our engineering team to validate feasibility of your proposed design • Translation of your design into a CAD layout • Formal design review with our technical team • State-of-the-art microfabrication of your design • Packaging and testing of the fabricated devices • Ability to imprint text (such as your name) on the lead
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NeuroNexus offers both conventional and high density lead technologies.
Conventional Lead Technologies
High Density Lead Technologies
• History of clinical use • Robust mechanical properties • Body compliant
• High channel count, high density • Ultra flexible • Can be integrated into form factors of conventional systems • Customizable shape and electrode coverage
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LEADS FOR BRAIN/SPINAL CORD SURFACE
Images not to scale.
SPE CIFICATIO N S
Conventional
HD
Number of Channels
8, 12
16, 32, 64+, customizable
Substrate
Silicone/Polyurethane, millimeter thickness
Thin-film, micron thickness
Flexibility
Body compliant
Ultra-flexible
Electrode Material
Platinum Iridium
Platinum
Electrode Coverage
Millimeter spatial resolution
Micron spatial resolution
Impedance
kΩ range
kΩ - MΩ range
Maximum current
mA
µA - mA
Usage
Stimulation
Stimulation, Sensing (ECoG, µECoG, CAP)
Regulatory Status
FDA Approved
In Process
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LEADS FOR DEEP BRAIN MAPPING OR STIMULATION
Images not to scale.
SPE CIFICATIO N S
Conventional
HD - Stimulation
HD - Mapping
Number of Channels
8, 12
24, 48, customizable
16, 32, customizable
Substrate
Silicone, millimeter thickness
Thin-film with silicone/ polyurethane backing
Thin-film combined with conventional wire
Electrode Material
Platinum Iridium
Platinum
Platinum
Electrode Coverage
Millimeter spatial resolution
Micron spatial resolution
Micron spatial resolution
Impedance
kΩ range
kΩ - MΩ range
kΩ - MΩ range
Maximum current
mA
µA - mA
µA - mA
Usage
Stimulation
Stimulation, Sensing (AP, LFP)
Stimulation, Sensing (AP, LFP)
Regulatory Status
FDA Approved
In Process
In Process
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INTRACORTICAL LEADS
SPE CIFICATIO N S
HD
Number of Channels
64, 128
Substrate Material
Silicon
Electrode Material
Iridium
Electrode Resolution
< 50 µm, customizable
Usage
Stimulation (electrical and optical), Sensing (Action potential, Field potential)
Regulatory Status
In Process
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NERVE LEADS
Images not to scale.
SPE CIFICATIO N S
Conventional
HD
Number of Channels
2-3
12, 24, customizable
Substrate
Silicone/Polyurethane, millimeter thickness
Polyimide, micron thickness
Flexibility
Flexible
Ultra-flexible
Electrode Material
Platinum Iridium
Platinum
Electrode Coverage
Millimeter spatial resolution
Micron spatial resolution
Impedance
kΩ range
kΩ - MΩ range
Maximum current
mA
µA - mA
Usage
Sensing
Sensing, Stimulation
Regulatory Status
FDA Approved
In Process
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Clinical SmartBox™ Platform - Recording Module*
LE AR N MORE Visit our YouTube channel to learn more about our products: youtube.com/TheNeuroNexus
The NeuroNexus SmartBox™ is a portable control and data acquisition system. • State-of-the-art technology, affordable pricing • Record up to 256 channels simultaneously • Up to 30 kHz sampling rate per channel • 16-bit ADC resolution, 15 µV smallest detectable signal • Electrode diagnostic (impedance check) and site conditioning mode • Wide variety of signals supported: EEG, EMG, action potential, field potential, pulsation • Portable with optional battery pack - take your recording system and laptop with you, and record from anywhere
Above: SmartBox™
• DAC out for audio monitoring
Inset: GUI
• Arrives ready to go, with minimal setup required; Laptop included
*Available in 2016
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Clinical SmartBox™ Platform - Stimulation Module*
Desktop Stimulation Module
• Can be integrated to perform simultaneous recording and stimulation • 25 stimulation channels with independent constant current sources • Stimulate up to 15 mA • Highly flexible programming to support advanced stimulation protocol
Wearable Stimulation Module
• Wirelessly controlled (up to 1 meter range) • Can be battery powered (2 weeks of operation with typical usage) • Arbitrary waveform generation • Implantable, wearable, and desktop versions available
Implantable Stimulation Module Images not to scale.
*Available in 2016
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Surgical Consultation & Neural Analytics Adapting to new technology and techniques can be difficult. NeuroNexus staff engineers and scientists have decades of combined experience, and we can help you reduce your ramp-up time so you can focus on your research.
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NOTES
Currently not available for sale
655 Fairfield Ct., Ste. 100 / Ann Arbor, MI 48108, USA neuronexus.com / +1.734.913.8858 (Phone) / +1.734.786.0069 (Fax)
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