The Franklin - Notting Hill & Ealing High School's Science Dept Newsletter - Issue 5 (Spring 2022)

Page 29

How to grow a heart By Maia Roman Year 10

What if I told you that there was a way

The blind form of this incredible fish is also

you could regrow your own heart if it got

science. Roughly 1.5 million years ago, some

damaged?

extremely important for future groundbreaking

Mexican river tetras, living in the Northern I am actually going to talk about a

Mexican rivers, got washed into caves by

certain species of fish that can already do this

floodwaters and became trapped there. So what

themselves.

did they do? They adapted. These tetras lost the Astyanax

pigmentation in their skin and they lost their

Mexicanus and its river dwelling form is able to

eyesight due to the permanent darkness that

self heal its heart tissue. When compared to its

surrounded them. Some had only partial

adaptation, the blind, cave dwelling Mexican

eyesight and others went completely blind or

tetra which is unable to self heal its heart tissue,

even without eyes. They have even adapted to

studies showed that two genes, known as Irrc10

have a better sense of smell via taste buds all

and caveolin, were much more active in the

over their heads, which allows them to find food

river fish following heart injury. Scientists then

more easily. These cave dwelling tetras are able

experimented on Zebrafish, a different species

to store four times more energy than the river

with healing abilities, and turned off the Irrc10

dwelling tetras, and they store it in the form of

gene. They found that without this particular

fat. This adaptation enables the fish to deal with

gene, the Zebrafish was unable to fully repair its

inconsistent food supplies of algae in the cave

heart without scarring. Scar tissue prevents the

more efficiently. Sources say that because of

heart from functioning properly because it

such a “sudden environmental change, their

reduces its ability to pump blood. Irrc10 and

phenotypic (characteristic) evolution occurred

Caveolin are present in humans, and Irrc10 is

more rapidly within about 20 000 years and is

actually related to a medical condition known

probably still ongoing.” Although 20 000 years

as dilated cardiomyopathy.

doesn’t seem very fast to us, when compared to

The

species

of

fish

is

called

could

other animals such as the giraffe, which

seriously benefit the treatment of people with

supposedly didn’t fully evolve to be truly long

heart conditions. At the moment the only

necked until 7.5 million years ago, that is a very

treatment is a heart transplant which does not

fast adaptation.

Further

research

into

these

genes

have guaranteed success because the body could easily reject it and attack the new heart

Scientists are also very interested in this

cells.

adaptation of the fish because it could lead to a

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