In recent years, a 'more-than-human' turn in environmental humanities, social sciences and science studies has linked a range of concerns about anthropogenic climate change, sustainability, post-humanism, re-wilding, de-growth, and hybrids. The scope of these considerations is wide and interdisciplinary, and opens new questions for scholars and practitioners interested in the built environment —about non-humans as architectural subjects, nature/society boundaries, questions of instrumentality and the assembled nature of (design) agency—particularly in light of ecological crises and climate change. This interdisciplinary panel discussion brought scholars, designers and artists together to reflect on the historical roles (expected and unexpected) of non-human others in crafting urban and regional landscapes, and the politics, biopolitics and aesthetics of more-than-human interactions. Organized by Nida Rehman, School of Architecture, Carnegie Mellon University.