Cosmetiscope - October 2016 by NYSCC Webmaster

OCTOBER 2016 • Vol. 22 No. 8

New York Society of Cosmetic Chemists

www.nyscc.org

Solids and Nanoparticles: Interactions with the Skin

…by Nava Dayan

any compounds incorporated into topical formulations are in their solid particulate form. Examples include zinc oxide in diaper rush ointment or in calamine lotion for chicken pox, and sunscreens containing both titanium and zinc oxide, as well as other powders such as mica and pigments. Some of these formulations are intended to treat and alleviate symptoms of irritation in partially compromised skin, while others, such as sunscreens or optically active powders, are intended to be applied to healthy intact skin and act merely on the very upper layer (no penetration needed) to protect from radiation or create an even-tone appearance, respectively. Some powders are incorporated for an enhancement of appealing sensation. When assessing potential routes for penetration into the skin, the following can be outlined: • Via the intercellular lipids; • Via the corneocytes; and • Via the follicular route. The intercellular skin lipids (located between corneocytes) are composed mainly of hydrophobic ceramides, long chain fatty acids, cholesterol, and cholesterol derivatives. They are organized in a gel crystalline rigid structure to control penetration. In 2003, Phil Wertz and Jennifer Hill published a paper describing molecular models of the intercellular lipid lamellae from epidermal stratum corneum.1 Their work examined electron density profiles measured from transmission electron micrographs of porcine stratum corneum prepared using ruthenium tetroxide. Dense band center-to-center measurements were consistent with a 5-3–5 nm arrangement; correlating to 13 nm band distances in the lamellar structures in between the corenocytes in the stratum corneum. This was clearly a very important finding with implications to skin barrier health; however, it is not clear if Wertz and Hill’s research suggests that

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unless a particle is on the low end of the nanometer scale, it will not partition into the stratum corneum. Most compounds partitioning into the skin are known to intercalate via the intercellular lipid lamellae; however, penetration via keratinized corneocytes is most likely to occur as well. Corneocytes are polyhedral, anucleated entities without cytoplasmic organelles, interlocked with each other and organized as vertical columns of 10-30 cells. As noted, they are embedded within a highly hydrophobic lipid matrix to form the stratum (Continued on page 2)

P R O F E S S I O N A L D E V E L O P M E N T S Y M P O S I U M October 6 • New Brunswick, New Jersey

2016 NYSCC BOARD OF DIRECTORS & PROGRAM CHAIRS CHAIR Rey Ordiales (732) 878-7798 reyordiales@outlook.com

CHAIR-ELECT Marie Thadal (609) 712-3716 chairelect@nyscc.org

TREASURER Cathy Piterski (201) 675-3799 cpiterski@essentialingredients.com

SECRETARY Giorgino Macalino (862) 324-2749 Secretary@nyscc.org

ADVISOR Kim Burch (609) 443-2385 Kim.Burch@elementis.com

HOUSE Mohamed Abdulla (973) 487-6572 house@nyscc.org

MEMBERSHIP John Carola JohnC@protameen.com

PROGRAM John Goffredo (267) 318-6168 john.goffredo@univarusa.com

COMMUNICATIONS Stephen Weinberg (973) 307-4854 webmaster@nyscc.org

SPECIAL EVENTS Gillian Ratto (723) 788-7320 Gillian.Ratto@elementis.com

COSMETISCOPE EDITOR Roger McMullen roger_mcmullen@fdu.edu

COSMETISCOPE ASSISTANT EDITOR Joe Albanese (908) 456-2968 joealbanese2@gmail.com

COSMETISCOPE ADVERTISING Bret Clark rbclark@ashland.com

COSMETISCOPE EMPLOYMENT Joel Diaz diaz.joel.a@gmail.com

Solids and Nanoparticles: Interactions with the Skin corneum. Filled with keratin, corneocytes exhibit limited capacity to absorb and retain water. Although some compounds, such as ethanol and oleic acid, were shown to penetrate corneocyte structure, a literature search reveals no substantial clear evidence for penetration of solid particles into the corneocyte body. Follicles are unevenly distributed throughout the body. The two extremes are probably the forehead, which is known to have the highest follicular density, and the soles of the feet, which contain no follicles. Studies are inconsistent with their reporting on the percentage of follicle distribution, ranging from 0.1% to 1%, or even 2%. Otbeg and coworkers note that the distribution as well as the size of the follicular opening differs between various anatomical locations. The follicle opening, according to this research, ranges between 70 and 170 Îźm.2

Size Matters When you consider the follicle as a shunt route into the vascularized dermis, one may think that particles that are less than 70 Îźm in size can penetrate through the follicle into the blood. However, this is not accurate. The follicle is filled with sebum, and the sebum flow is from the inside out. In addition, the follicle has an immune response mechanism protecting it from invasion of foreign substances and may respond by means of an inflammation reaction that will result in

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hyperkeratinization, which will clog the pore and prevent further penetration. Such compounds, depending on the specifics of the reaction, are called comedogenic or acneogenic, or they are identified as materials that provoke acne cosmetica.

Some studies claim that depending on the size and other properties of nanoparticles, and under specific conditions of penetration enhancement, they may generate a reservoir in the follicular shunt. For example, a study published in 2007 by Lademann and coworkers notes that nanoparticles with a 320 nm diameter were found in the follicle for up to 10 days after treatment.3 It was theorized that the movement of the hair fibers may act as a pumping mechanism pushing the nanoparticles deep into the hair follicles. Other studies demonstrate that particulate substances penetrate preferentially into the hair follicles and that the penetration depth depends on the particle size or on the base formulation used.4 To summarize, the potential routes for particle penetration, even at their nano-sized scale, are highly limited. If larger than a few nanometers, penetration via the intercellular lipids or through keratinized corneocytes may not be possible, and while partition into the follicle is theoretically feasible, it must occur under specific facilitating conditions or be conducted with the use of exceptional materials. Such discussion, of course, applies to healthy intact skin and may be very different when the skin is compromised for any reason. The interaction of a compound with the skin in its solubilized form differs profoundly from the same chemistry when in its particulate solid form. In fact, solid particles, unless applied to compromised skin or under unique conditions, are not expected

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to penetrate the skin. Similar assessment applies for large molecules such as polymers, which are also anticipated to remain in the upper stratum corneum and not penetrate beyond it. The fact that the skin sheds one layer of corneocytes per day and renews itself every month adds yet a dilution safety factor to this calculation. Considering the above analysis, when assessing the safety of interaction of particles with the skin, why do we need to test systemic endpoints such as cytotoxicity or genotoxicity? The scientific rationale for such can be explained by the following:

• Polymers and/or particles are not homogenous and may contain monomers and soluble impurities that potentially penetrate the skin. Since the cosmetic industry allows higher levels of impurities for its raw materials when compared to the pharmaceutical industry, such long lasting cumulative exposure may be of concern since the impurities may penetrate beyond the stratum corneum. • Compounds that are applied to skin do not have to physically penetrate it to impart a biological effect. We know for example that mere occlusion of the skin changes its biota population and leads to a cascade of biochemical events that can be detected in the living epidermis. • A variety of cosmetic and personal care applications are aimed at compromised skin, such as aftershave lotions, after-sun potions, peels, after-peels, and alike.

More Challenges Due to the animal testing ban and the emergence of in vitro cell culture methodologies, testing of solid particles for variety endpoints is V O L U M E

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limited and needs to be designed with care. If a slurry of solids is introduced to cells in culture, such as keratinocytes or fibroblasts, the cells will most likely die rapidly. Such a phenomenon, while it may be interpreted as a cytotoxicity reaction, is an artifact. This is because cells in a culture are much more vulnerable and sensitive to exogenous molecules as compared to the application of such compounds to in vivo skin. Futhermore, solid particles generate a toxic environment in culture systems that cannot be paralleled to the real life situation. If we test particles in such a manner, they will all test positive and will be wrongly classified as highly toxic. This would be a false positive result. Following the above rationale that particles should be tested for their impurities and soluble components, a more relevant approach would be to apply various concentrations of the test material in a dose-dependent manner. One could suspend the powder in the culture media, followed by vortexing and centrifugation, and then removing the clear supernatant, and introducing it to the culture in a variety of dilutions. This would aid in the identification of potential toxicity due to the presence of monomers and soluble impurities. Another approach could be using the reconstructed live epidermis model, such as EpiDerm FT, or fresh skin samples. Having a skinlike barrier, EpiDerm and similar models could be used to test for irritation resulting from particulate substances and sunscreen application. The EpiDerm Skin Irritation Protocol may be used for evaluating whether a particulate material has the potential to be a primary skin irritant. This protocol is validated by ECVAM (the European Centre for the Validation of Alternative Methods) and accepted by OECD (Organization for Economic Co-operation and Development) (TG 439) as a non-animal alternative to the rabbit Draize test. It uses 5% sodium dodecyl sulfate (SDS) as a positive control, and the endpoint of the study is cellular viability measured by the MTT colorimetric assay. This assessment involves NAD(P)H-dependent cellular oxidoreductase enzymes that may, under defined conditions, reflect the number of viable cells present. These enzymes are capable of reducing the MTT tetrazolium dye, 3(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, to its insoluble form (formazan), which has a purple color. According to this protocol, a compound that imparts mean tissue viability that is equal or less than 50% is considered an irritant while a compound that imparts more than 50% viability is considered a non-irritant. It is also highly advisable to tailor and design

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Solids and Nanoparticles: Interactions with the Skin the protocol in a manner that it covers potential safety concerns that are specific to the tested compound. Adding a tier of biomarkers tested at their protein level may be a wise approach if one wishes to gain an understanding of its potential effects upon chronic cumulative exposure. In summary, solid particulate non-soluble compounds, unless extremely small or applied to compromised skin, are not likely to penetrate healthy intact skin unless a means to compromise the barrier, such as permeation enhancers are used. Proximity to mucosal tissue (around the eyes or the

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mouth) should be addressed in a separate manner and considered if that is the intended use of the formulation. Study design in cell culture systems or skin models should be carefully planned so no false positive toxicity is generated due to sedimentation of the particles in the culture environment. Creative means and additional biological endpoints may be considered to assess potential known risk. This article originally appeared in the May 1, 2015 issue of Happi Magazine. Reprinted with permission; © 2015 Rodman Media.

References 1. P.W. Wertz and J.R. Hill, Molecular models of the intercellular lipid lamellae from epidermal stratum corneum, Biochim. Biophys. Acta Biomembranes, 1616, 121-126 (2003). 2. N. Otberg, H. Richter, H. Schaefer, U. Blume-Peytavi, W. Sterry, and J. Lademann, Variations of hair follicle size and distribution in different body sites, J. Invest. Dermatol., 122, 14-19 (2004). 3. J. Lademann, H. Richter, A. Teichmann, N. Otberg, U. Blume-Peytavi, J. Luengo, B. Weiss, U.F. Schaefer, C.M. Lehr, R. Wepf, and W. Sterry, Nanoparticles—an efficient carrier for drug delivery into the hair follicles, Eur. J. Pharm. Biopharm., 66, 159-164 (2007). 4. A. Patzelt, H. Richter, L. Dähne, P. Walden, K.H. Wiesmüller, U. Wank, W. Sterry, and J. Lademann, Influence of the vehicle on the penetration of particles into hair follicles, Pharmaceutics, 3, 307-314 (2011).

About the Author:

ava Dayan, Ph.D. has 25 years of experience in the skin care segment, and has yielded more than 150 publication credits in numerous industryrespected journals and four books. She was awarded the In-Cosmetics Gold Award for innovation and commensurate recognition from the NYSCC and the CRS for excellence. Dr. Dayan is the owner of Dr. Nava Dayan L.L.C, a skin science and research consultancy serving the pharmaceutical, cosmetic, and personal care industries. The services of Dr. Nava Dayan L.L.C. include: product feasibility evaluation in skin care; composition of R&D plans covering efficacy and toxicology; planning, execution, and data interpretation into claims, formulations, delivery for improved efficacy, and attenuated toxicity. A sample of her expertise includes: drug-skin interactions, bio-markers (genomics and proteomics), skin/age related sensitivities, inflammatory skin disorders, innate immunity, and biota. Dr. Dayan can be contacted by e-mail at: nava.dayan@verizon.net.

Call for Papers

he Cosmetiscope editorial committee invites all interested parties to submit feature technical articles for publication in the NYSCC monthly newsletter. Authors of feature articles are eligible to win the prestigous NYSCC Literature Award ($1,000) for the best front-page article published during the calendar year. Also, authors receive $200 reimbursement to attend a theatrical performance of their choice. Writing an article for your peers is a very rewarding experience, both personally and professionally, and would reserve your place in NYSCC history. You may choose whatever topic you feel would be interesting to fellow colleagues in our industry. We also welcome any other types of commentaries or articles that may be published in the Career Corner, Technical Tidbit section, or as a Letter to the Editor. Please send correspondence to: roger_mcmullen@fdu.edu.

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NYSCC Professional Development Symposium October 6, 2016

Kean University, STEM Building • Union, NJ

t this year’s NYSCC Professional Development Symposium we plan to help expand our members’ educational awareness beyond our industry’s latest technologies by offering a focus on how each member can excel by being their BEST SELF in a very competitive and challenging market. The program will focus on key habits of successful people and how to direct our passion to achieve results while still maintaining the proper balance between life and work. As an added bonus, we have included a fun and informal networking Oktoberfest to this event to aide our members’ professional development by meeting and learning from each other.

• Registration… Making Personal Personal Car Caree Beautiful®

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Attendee Type Early Registration Late Registration Members $55 $65 Non-members $75 $85 Students/Unemployed $20 $30 Emeritus $0 $10 To register for this event, please visit the Events section of the NYSCC website (www.nyscc.org).

• Event Committee… • Steve Fantano, Chair – Mobius Sales Group (slfantan@mobiussales.com) • Daria Long, Chair – Lucas Meyers Cosmetics (daria.long@lucasmeyercosmetics.com) • Mohamed Abdulla – SEPPIC (mohamed.abdulla@airliquide.com) • Jenna Jelinski – IMCD US – (jennajelinski@yahoo.com)

• Location… The Professional Development Symposium will be held at Kean University’s new STEM Building (New Jersey’s Center for Science Technology & Mathematics) with a view of the Manhattan skyline. Plenty of free, adjacent parking awaits us at this new venue for the NYSCC. Use the following address for your GPS: 1075 Morris Avenue, Union, NJ.

• Guest Speakers…

Lifestyle Balance for Optimum Performance – Josh Skube

e have all fallen victim to narrowing the scope of our attention onto a solitary goal. Often times, we laser-focus our attention on an important work-related goal. It is true that more time and energy and less distraction will lead to better results for our goal. However, this intense, prolonged focus can diminish the quality of other, equally important, aspects of our life. Inevitably, everything held dear, even the task at hand, begins to unravel. What if I told you that sacrificing the other aspects of your life wasn’t necessary? What if I told you that achieving your goal would not suffer either? Finding your lifestyle balance will not only help you achieve your goal, but make you happier and more productive during the process. Let us begin with identifying one powerful habit that, if you could consistently achieve it, would advance your quest for lifestyle balance and optimum performance. You will learn ways to foster this positive habit and make it stick through implementation of proper mindset, motivation, and effective strategies. Once this habit becomes a part of you again, the lights will be on and shining bright, the sounds you listen to will be vibrant, mental acuity will be sharp, and life will again be in harmony. With the discovery of lifestyle balance we will be reaching our goals by increasing productivity through efficiency and focus, all while living in the moment.

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Josh Skube

Mr. Skube, graduated from Indiana University with an M.S. degree, specializing in Exercise Physiology and Human Performance. His focus on the sport psychology behind mentally preparing for and getting through extreme stress is integrated in all facets of his training and teaching. For 15 years the University of Notre Dame has sought Skube’s leadership and teaching excellence in guiding students toward positive health habits. His course topics have focused on stress management, sleep management, nutrition, healthy relationships, fitness and exercise prescription, substance abuse, weight management, eating disorders, time management, and behavior modification. Skube’s influence at the University of Notre Dame has also impacted the athletic domain. As the assistant coach for women’s and men’s swimming, Skube has guided the training of 28 NCAA participants, 8 AllAmericans, and 16 honorable mention All-Americans. He is celebrated for helping to coach 5 Big East women’s team championships and the men's first Big East championship in 2004-2005. He has been instrumental in the success of Olympians—Jilen Siroky (United States) and Christel Bouvron (Singapore)—as well as the American record holder and first NCAA champion for the University of Notre Dame, Emma Reaney. Skube is a USA triathlon certified coach and accomplished triathlete competing in the Ironman 70.3 world championships and coaching rising youth to the ITU short course world championships.

Living Principles for True Success – Kathleen Sullivan, Ph.D.

his highly interactive, engaging session will reference the principles of the 7 Habits to frame our exploration for achieving true success. You will develop a tool box of practical ideas to enhance your effectiveness at work and for greater personal satisfaction. We will detect blind spots that detract from achieving what truly matters to you and replace those barriers with concrete solutions. We will integrate the challenges presented from Josh Skubes’ session into our application of the key success principles. n

Kathleen Sullivan, Ph.D.

Dr. Sullivan received her doctorate degree in English from the University of Notre Dame and for 25 years has created and taught leadership programs for the University and for corporations in diverse fields. She has worked with Dr. Stephen Covey, author of the 7 Habits of Highly Effective People, to produce a series of television programs on The American Family: A Challenged Tradition. In 2013, Kathleen created Leadership Through the Barn Door where companies apply principles of the 7 Habits by working with horses. Currently, she is a faculty member at Indiana University of South Bend, directing a program that helps at-risk students succeed in college. She also teaches in the University of Notre Dame’s Pathways to Success for Engineering and Science Students.

NYSCC Professional Development Symposium Oktoberfest Networking Event • October 6

Kean University, STEM Building • Union, NJ

he NYSCC Professional Development Symposium will end the day with an Oktoberfest networking event that will include a cocktail hour with passed hors d’oevres followed by a dinner with traditional German fare. During the networking event you will have the opportunity to: • Learn from your peers about how the SCC has helped them with their careers. • Meet with higher educational institutions with programs in cosmetic chemistry. • Experience a German Oktoberfest. A few items from the Oktoberfest dinner menu: • German Pretzels • Vegetarian Goulash • Zwiebelkuchen – German Onion Tart • Braised Cabbage • Beer Bratwurst with Caramelized Sauerkraut • German Chocolate Cakes • Beer Basted Knockwurst • Apple and Almond Strudel • Wiener Schnitzel • Traditional German Beer and Wine

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NYSCC Rheology Symposium — Practical Considerations and Demonstrations November 15th Cook Campus Student Center • Rutgers University New Brunswick, NJ

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n continuing with tradition, the NYSCC will be hosting its biannual Rheology Symposium this year. This is a great event that promises to provide a cornucopia of educational information bringing rheology and cosmetic science together. Attendee registration will begin this summer. At this year’s symposium we plan to give attendees the opportunity to see “rheology in action.” Several instrument suppliers will demonstrate case studies to highlight test methods and data analysis relevant to cosmetic product development. This format is designed to encourage attendees to learn from the demonstrators and from each other. In addition to the practical demonstrations, invited speakers include Dennis Laba (Review of rheological terms), Rhyta Rounds (Product packaging), and Professor Christopher Macosko of the University of Minnesota.

• NYSCC Rheology Symposium Agenda… 8:30 a.m. – 9:00 a.m.

Breakfast and Registration

9:00 a.m. – 9:15 a.m.

Opening statements

9:15 a.m. – 9:55 a.m.

A Brief Review of Rheological Terms – Dennis Laba

9:55 a.m. – 10:35 a.m. 10:35 a.m. – 11:00 a.m.

Coffee Break

11:00 a.m. – 11:40 a.m.

Demo I

11:40 a.m. – 12:20 p.m.

Demo II

12:20 p.m. – 1:30 p.m.

The Product Packaging – Rhyta Rounds

Lunch and Exhibits

1:30 p.m. – 2:15 p.m.

Rheology: A Tool for Sensory Product Development – Prof. Christopher W. Macosko

2:15 p.m. – 2:55 p.m.

Demo III

2:55 p.m. – 3:35 p.m.

Demo IV

3:35 p.m. – 3:55 p.m.

Coffee Break

3:55 p.m. – 4:35 p.m.

Demo V

4:35 p.m. – 4:45 p.m.

Closing statements

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Speaker Abstracts and Biographies…

A Brief Review of Rheological Terms

– Dennis Laba

o understand Rheology, you have to understand the language of the Science. Words like shear stress, pseudoplastic, and viscoelasticity are not typically used in every day conversations, but when formulating cosmetic or personal care products, an understanding of these terms can make the difference between developing a good product and a successful product. A number of basic rheological expressions will be reviewed, so that more complex concepts discussed later in this symposium may be more quickly understood.

• Biography Dennis Laba is currently the Director of Regulatory Affairs and QC at PRESPERSE Corp., located in Somerset, NJ. He has over 35 years of experience in the cosmetic industry with many of them in technical roles. He has authored a number of professional papers, edited a book on rheology in Marcel Dekker’s Cosmetic Science and Technology Series, holds a number of US Patents, and was a contributing author in the latest edition of Harry’s Cosmeticology. He earned his B.S. degree in Biology from Rutgers University, and his M.S. degree in Industrial Pharmacy from Long Island University. Mr. Laba is a Fellow of the Society of Cosmetic Chemists, and has held previous technical and marketing positions with Elementis Specialties, Reheis Chemical, and Block Drug.

Time Dependent and Accelerated Flow Shear Effects: The Product Packaging

– Rhyta S. Rounds

consumer's positive experience in dispensing a product depends on a sound marriage of rheology with container design/selection. This is not a trivial relationship and can cause a number of problems in the launch of a new or improved product. Frequently this is due to the misunderstanding of the nature of the product and a misidentification of the relevant rheology attributes, since there are many to consider. Time dependent shear effects are critical, especially transient flow at flow inception. Rheology is a very practical flow simulation tool. Designed properly with the flow objective in mind, rheology metrics can guide the design and selection of product packaging. This is especially true for nonNewtonian formulations that are complex structured fluids or soft solids, as these materials can exhibit rich time-dependent shear effects, especially at flow inception. Whether developing a model for computational flow dynamics or estimating flow resistance during flow through the package geometry, understanding the flow resistance as a function of time and shear rate or shear stress is key. We will review the transient flow behavior of various cosmetics and discuss experimental errors and artifacts confounding these studies. Examples will be provided of stress growth functions and accelerated flows in the appropriate experimental ranges, simulating dispensing conditions, with a discussion of the dimensionless Deborah and Weissenberg numbers. The breadth of experimental ranges will be explored as these are set by the ultimate consumers.

• Biography Rhyta S. Rounds, Ph.D. is the Director at Fluid Dynamics, Inc, a rheology testing and research laboratory, located in Flemington , NJ. With advanced degrees in chemical engineering, Rhyta has specialized in the science of rheology throughout her industrial career with an emphasis on complex structured fluid systems. She has extensive experience in the testing and sensory analysis of many personal and household care consumer products. Of special interest to her is the design of custom tooling and instrumentation with methods development for various complex consumer perceived product attributes. One example is the ideation of "lubricity" through a novel test station, which is patent pending. Rhyta is the co-inventor of 14 patents. Rhyta enjoys teaching hands-on rheology classes at Fluid Dynamics to industrial participants and (Continued on page 10)

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NYSCC Rheology Symposium

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working with clients to better understand the properties and behavior of their products and/or raw materials under a broad range of process or in-use conditions. She is celebrating 19 years with Fluid Dynamics this year. When not at work, Rhyta is an avid Nikon landscape/floral photographer, equestrienne, and gardener, raising rare Cymbidium and Oncidium orchids.

Rheology: a Tool for Sensory Product Development

– Christopher W. Macosko

heology can relate the stress and strain response of liquids and soft solids to their structure and performance. We will define basic rheological measurements and show examples how they can be used to guide formulation development and product quality. For example, the elastic modulus of chewing gum needs to be in a particular range at 37 °C for a consumer acceptable mouth feel. On the other hand, extensional strain hardening is critical for good performing bubble gum. As another example, the viscosity at high shear rates relates to the perception of smoothness in rubbing on face cream and is used along with modulus to control production.

• Biography Christopher W. Macosko, Ph.D. is a Professor in the Department of Chemical Engineering and Materials Science at the University of Minnesota. He (and the students in his group) create multiphase polymer microstructures via process flows and chemical reaction. They carry out research on polymer blending, polyurethane foaming, dispersion of nano-filler in polymers, and creation of nanoparticles for drug delivery. Macosko has also been active in developing new rheological test methods and their applications. Professor Macosko is the author of the popular text: Rheology: Principles, Measurements, and Applications. The Macosko Group has produced over 420 publications and has been home to nearly 100 Ph.D. and M.S. students, post-doctoral scholars, and visiting scientists. Macosko is also the Director of IPrime, the Industrial Partnership for Research in Interfacial and Materials Engineering at the University of Minnesota. He may be reached at: macosko@umn.edu.

• Registration Information (prices prior to November 11)… • SCC member – $35 • Non-member – $75 • Student (ID required), unemployed – $10 • Emeritus – $0 To register, visit the Events section of the NYSCC website (www.nyscc.org). Students are encouraged to attend and take advantage of the new member benefits. For a list of these benefits, see the membership tab on the NYSCC website.

• Sponsorship Opportunities… • Posters – $100 • Exhibit table – $200 All sponsorship categories include one attendee registration. For more information on sponsorship opportunities, please contact Julia Broglie (Julia.broglie@covestro.com)

• Event Chairs/Organizers… • • • •

Daphne Benderly, Ph.D. – Presperse (dbenderly@presperse.com) Joe Albanese – Sytheon (joe@sytheonltd.com) Mohamed Abdulla – SEPPIC (Mohamed.abdulla@airliquide.com) Julia Broglie – Covestro (julia.broglie@covestro.com)

• Symposium Location… Rutgers University, Cook Campus Student Center (map on page 8) 59 Biel Road, New Brunswick, NJ Parking will be available in Lots 99C and 99D. 10

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The Soul & Science of Beauty. www.evonik.com/personal-care

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FACEBOOK: NEW YORK LINKED IN: NEW YORK SCC TWITTER: @NYSCC INSTAGRAM: NYSCCMAIN SOCIETY OF COSMETIC CHEMISTS These connections are possible by the NYSCC Social Media Committee

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Society of Cosmetic Chemists 2016 Continuing Education Program Schedule

he SCC is dedicated to providing educational opportunities that serve the needs of professionals in our industry. Our instructors are highly qualified industry experts. You will come away from these small, interactive courses having gained the knowledge needed to advance your professional development.

October 5 Scale-up and Processing Cosmetic Formulations • David Yacko October 14 Recent Advances in Polymers and Macromolecules in Personal Care • Robert Lochhead, Ph.D. November 14 CGMPs for Cosmetics and OTCs • Karl Popp, R.Ph. December 8 Clinical and Instrumental Testing of Skin and Skin Care Products • Randall Wickett, Ph.D. December 14 Fragrance in Personal Care • Steve Herman To register or to learn more please visit www.scconline.org. If you have questions please call (212) 668-1500 or email dscelso@scconline.org. All courses will be at the SCC National Office in New York City unless otherwise detailed. *If four or more employees from the same company register, $25 can be deducted off each registration fee. **Customized Onsite Courses can also be arranged. Please call Doreen Scelso at (212) 668-1500 for further information

Monthly Meeting Group Discount The NYSCC is offering a group discount of 15% to companies who send 5 or more employees to a monthly meeting. All five employees would need to be registered at the same time to receive the discount. Once purchased, registrations are non-refundable.

JOURNAL OF COSMETIC SCIENCE The Official Journal of the Society of Cosmetic Chemists

CALL FOR MANUSCRIPTS

he Society of Cosmetic Chemists is soliciting scientific manuscripts concerned with cosmetics or the sciences underlying cosmetics, as well as papers of interest to the cosmetic industry for publication in the Journal of Cosmetic Science, The Official Journal of the Society of Cosmetic Chemists. The JOURNAL will consider manuscripts for publication in the following categories, provided they are prepared in proper scientific style and adequately referenced: • Original articles • Review articles • Technical notes • General articles • Preliminary communications • Letters to the Editor SUBMISSION OF MANUSCRIPTS Manuscripts submitted for publication should be accompanied by a cover letter and sent via e-mail to dscelso@scconline.org. Additional information is available from the SCC National Office: www.scconline.org.

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Upcoming 2016 NYSCC Events Calendar • For updated NYSCC information, visit us on the web at: www.nyscc.org • For National SCC information: www.scconline.org

Premium Ingredients. Custom Solutions.

October 6 Personal Professional Development Symposium, Kean University, Union, NJ Oct. 30-Nov. 2 IFSCC Congress, Orlando, FL November 15 Rheology Symposium, Cook Campus Student Center, Rutgers University December 1 NYSCC/SCC Officers Installation and End of Year Celebration

Deborah Bagnuolo 844 458 7111 lvlomas.com

NYSCC Historian

he NYSCC Executive Board would like to welcome our new Historian, Sophia Chen. If there are any historical documents, photographs, etc. that you would like to share with other members of the NYSCC, please contact Sophia. She can be reached at historian@nyscc.org.

Employment Opportunities For complete ads please go to the NYSCC website: https://www.nyscc.org/employment-listings.html.

n Account Manager – Northeastern Territory EES Cosmetic Solutions, New Jersey region

n QC Document Control Specialist ChemAid Laboratories, Saddle Brook, NJ

n Staff Scientist – Analytical Lead – Skin Care (Sun Screens) Edgewell Personal Care, Allendale, NJ

n Regulatory Chemist Sarkli-Repechage Ltd., Secaucus, NJ

n Sales Manager ChemAid Laboratories, Saddle Brook, NJ

n Marketing Administrator Inolex, Inc.

n Senior Research Scientist/Technical Associate Colgate-Palmolive, Piscataway, NJ

Make note of it… Send news of interest, guest editorials, and comments to Roger McMullen, Editor • E-mail: roger_mcmullen@fdu.edu

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