Silver Diamine Fluoride: Science, Practice, and Potential

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Silver Diamine Fluoride: Science, Practice, Potential

Oral Health America Webinar Series August 30, 2018


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/Oral Health America

/Oral Health America

@Smile4Health

@Smile4Health

2018


HOUSEKEEPING INFORMATION • •

Please remember to MUTE your phone. Questions are welcome! We’ll allow 10-15 minutes after the presentation for questions. • Questions will be accepted in writing through the control panel on the upper right hand of your screen. • Submit questions at any time; we will address them at the end of the presentation. • Webinar is being recorded; for rebroadcast on OHA’s website – OralHealthAmerica.org • Your feedback is important to us. Please take our brief webinar evaluation after this session; link will be sent via email.

2018


CE Credit Available

2018


ABOUT ORAL HEALTH AMERICA America’s leading national oral health nonprofit focused on the nation’s oral and overall health for 63 years, with particular emphasis on children and youth, older adults and Americans whose voices are not wellrepresented in oral healthcare conversations. OHA employs strategic partnerships and communications to connect the dots between oral and overall health

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CAMPAIGN FOR ORAL HEALTH EQUITY

WISDOM TOOTH PROJECT®

2018


Early Childhood Caries Prevention Project

School-Based Prevention Programs

Demonstration Projects

Product Donation

Enrichment

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toothwisdom.org

Advocacy

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Professional Symposia

Demonstration Projects

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Addresses oral health inequities in our society and identifies possibilities for closing the oral health divide in America.

The campaign strives to: Educate and engage the public, including policymakers, about the importance of oral health for overall health

Emphasize the need to prioritize oral disease alongside other chronic health conditions Lead, participate and observe on legislative issues impacting oral health policies critical to OHA, our programs and stakeholders 2018




Question and Answer Session • Questions are welcome! This session may last for 10-15 minutes. • Write your questions in your control panel on the upper right hand of your screen. • Submit questions at any time.

2018


CE Credit Available

2018


Contact Information

Dr. Michael Helgeson • mhelgeson@appletreedental.org

Dr. Ryan Quock •

ryan.quock@uth.tmc.edu

David Martin • David.martin@oha-chi.org

2018


THANK YOU! Let’s improve the oral and overall health of all Americans together.

2018


Silver Diamine Fluoride: Science, Practice, Potential Webinar August 30, 2018: 2pm-3pm CST


Thanks to the

Dental Trade Alliance Foundation


Thanks to

3M Oral Care


We’ll share three stories… • An 18 month old facing hospitalization for general anesthesia

• A middle aged adult struggling with limited Medicaid coverage and potential loss of his front teeth • A frail elder in hospice with multiple failing teeth, fearing another abscess


Objectives… • We want help you to understand the basic science of Silver Diamine Fluoride (SDF) - what it is and how it works. • We want you to learn about our experiences introducing SDF to our team of dentists and dental therapists and then deploying in practice. • And finally, we want to share our hopes for the promise of SDF with a focus on its benefits for patients across the lifespan


1. The Science of SDF


What is SDF? • Ag(NH3)2F – silver and fluoride ions

in colorless ammonia solution • Various concentrations – most studied is 38% SDF • 38% SDF contains ~44,800 ppm F(compare with 22,600 for NaF varnish)

Walker D, Yee R. Arrest of caries technique (ACT): appropriate technology for the clinician and for disadvantaged communities in Nepal. Accessed on August 6, 2015 at http://www.scribd.com/doc/32660152/Arrest-of-Caries-Technique#scribd

Rosenblatt A, Stamford TCM, Niederman R. Silver diamine fluoride: a caries “silver-fluoride bullet.” Journal of Dental Research 2009;88(2):116-125.


What does SDF do? • Silver diamine fluoride (SDF)

has been studied outside the United States since the late 1960s. • Ag(NH3)2F arrests existing active caries lesions and prevents future lesions.


How does SDF work? • • •

Silver-salts stimulate dentin sclerosis & calcification Silver nitrate acts to kill bacteria Fluoride aids in remineralization and prevention Rosenblatt A, Stamford TCM, Niederman R (2009) Silver diamine fluoride: a caries “silver-fluoride bullet.” Journal of Dental Research 88(2) 116-125.


2. The Practice of using SDF


A PPLE T REE D E N T A L Access • Compassion • Excellence


In our 33rd year!


Minnesota Centers for Dental Health 130 Community Sites • Low income children and their families • Adults with disabilities

• Seniors and elders in long-term care • Urban and rural communities


Total Age Distribution, 2017 13,151

31,258 individual patients treated 87,633 dental visits and screenings provided 7,386 5,222 3,183

2,250 66

Under 21

21 to 44

45 to 64

65 to 84

85 to 99

Over 100


Minnesota 32 Years

MN

CA

California

NC

2 Years

LA

Apple Tree Programs and Replications

Louisiana 16 years

NC

North Carolina 19 and 20 years


Our “Centers for Dental Health” are the “hub” for mobile delivery of care in the surrounding community


Community Collaborative Practice

Collaborating to deliver oral health services where people live, go to school, or receive other health and social services


Cloud-Based Electronic Health Record


Apple Tree’s “Multi-Site Delivery Vehicle”












Implementing SDF at Apple Tree


Relevance of SDF for Vulnerable Patients • Children

• better tolerated by very young / pre-cooperative patients • preventing the need for general anesthesia • Adults • limited benefits / treatment options in public programs • Older adults

• high risk / low access


Timeline of SDF Implementation Fall 2015 Apple Tree staff intro to SDF

2016 Apple Tree pilots, then implements SDF in Centers

2015

4/15 NOHC J Horst Presentation on SDF

2016 11/15 Medicaid Committee recommends SDF coverage

2017 Apple Tree pilots, then implements SDF in LTC

2017

2018

10/16 -10/17 DTAF funded a pilot project in Long-Term Care 1/16 MN Medicaid covers D1354


Dr. Quock educating Minnesotans on Silver Diamine Fluoride


Preparation for SDF Implementation For Apple Tree staff • Lunch and learn sessions with an Elevate Oral Health representative • Apple Tree protocol development based on UCSF • Staff SDF education sessions • Customized EHR for SDF tracking / Open Dental • Talking points for Care Coordinators


Preparation for SDF Implementation For patients • Education sheet for Patients and Responsible Parties

• Letters to Directors of Nursing • Informed Consent with photos


Staff Instructions


Care Coordinator Talking Points


Information for Directors of Nursing and long-term care staff



Information for Nursing Facility Residents



Informed Consent



Implementation Strategy - Centers • 110 clinical and administrative staff, including • 90 dentists, dental therapists, hygienists, and assistants

• 20 care coordinators • Initial pilot with select dentists and dental therapists at Centers for Dental Health. Feedback incorporated.

• Expansion to all clinic-based clinicians, beginning with dentists and dental therapists and allowing clinical teams to determine when/whether to delegate to hygienists and/or assistants.


Implementation Strategy - LTC Facilities • Pilot in LTC setting, with select dentists and facilities, feedback incorporated prior to expansion to all on-site clinicians • Eight dentists, two dental therapists, and six dental therapy students provided SDF treatments for LTC residents during the pilot. • More than 75 staff members of 35 long-term care facilities received information about SDF as new treatment option for their residents and reinforcing the importance of oral health.


Sites, Patients, SDF Treatments SITES & CENTERS

PATIENTS

SDF TX

DECLINED TX

NURSING FACILITIES (35)

216

462

20

COON RAPIDS

20

35

FERGUS FALLS

90

195

HAWLEY

48

79

MADELIA

131

180

MOUNDS VIEW

29

70

ROCHESTER

29

76

1

TOTAL

563

1,097

30

SDF Treatments through 10-31-17

8

1


25 anteriors 140 posteriors

SDF by Tooth # in Long-term Care pilot

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

21

20

19

18

17

68 anteriors 212 posteriors

32

31

30

29

28

27

26

25

24

23

22


Long-Term Care Age Distribution 15 10

216 LTC patients received 462 SDF treatments

5 0

Age 47 51 54 59 61 66 68 70 72 74 76 78 80 82 84 86 88 90 92 94 96 98 102


Center Patient Age Distribution 30 25

346 Center patients received 635 SDF treatments

20 15 10 5 0 Age 4

7

10 13 16 19 22 25 28 31 34 37 40 43 47 50 53 57 61 64 70 75 81 94


Children 81% Adults 56% Older Adults 75% Preventively 36% Suspect Caries 44% Caries 81% Occlusal Surfaces 56% Interproximal Surfaces 50% Gingival Surfaces 63% Subgingival Surfaces 56% Prior to Restoration 44% Instead of Restoration 75% Other 19%


Highly Likely 43% Likely 50% Unlikely 1% (respondents had not yet used SDF) Would Not Recommend 0%


Clinical Cases and Q&A with Dr. Quock


Apple Tree Mounds View Center Restoration after SDF August 2, 2017


Before SDF

After SDF


After SDF

After Restoration


Q&A with Dr. Quock


Is there a limit to the number of teeth treated with SDF at any one appointment?

One drop is about 0.05 mL and treats 5 teeth

SDF contains about 44.8 mg F per mL, so one drop contains about 2.2mg F

The acute toxic dose for a 20lb. child is about 45 mg F


Please discuss the pros/cons of applying SDF and restoring over it on the same appointment.

PRO: Tooth gets restored the same day

CON: Don’t get to clinically observe the arrest of the lesion


Evaluation of SDF Outcomes


How long after treatment should one wait to assess outcomes? •

No well-defined protocols. It’s the clinician’s expertise that comes in.


When SDF is used off-label under a restoration, how can you assess whether there is new decay?


How does an SDF treated surface look on x-rays? Do you have photos of radiographic images?


Any experience with use to arrest decay under crowns with questionable prognosis for older adults?


3. The Promise of SDF


Lessons Learned Planning • Patients/Parents are receptive - ie informed consent is important but staining less of a barrier than anticipated • Challenging to incorporate a paradigm shift into day-to-day practice • Multiple educational opportunities helpful Clinical • Evaluation of caries arrest raised questions for many clinicians • Adjacent areas also darkened beyond what was anticipated and restorations with dark margins or grey appearance • Time / experience necessary for clinicians to incorporate into their practice


SDF Medicaid coverage

• D1354 Interim Caries Arresting Medicament Application • Once per six month; • tooth number required

• cannot be formed on the same date as D1206 and D9910




Closing with three stories‌


Avoiding general anesthesia‌


Fearing the loss of front teeth‌

Note: This is not the patient


Preventing painful abscesses … • A call from a dental school classmate • His mother lost two crowns after entering hospice • She couldn’t be transported and had complications following recent oral surgery • We sent an experienced collaborative practice hygienist to do a house call Note: This is not the patient


Additional Reading…


Chibinski AC, Wambier LM, Feltrin J, Loguercio AD, Wambier DS, Reis A. Silver diamine fluoride has efficacy in controlling caries progression in primary teeth: A systematic review and metaanalysis. Caries Research 2017;51:527-541.


Oliveira BH, Rajendra A, Veltz-Keenan A, Niederman R. The effect of silver diamine fluoride in preventing caries in primary dentition: A systematic review and meta-analysis. Caries Research 2019;53:24-32.


Hendre AD, Taylor GW, Chavez EM, Hyde S. A systematic review of silver diamine fluoride: Effectiveness and application in older adults. Gerodontology 2017:1-9.


Mei ML, Lo ECM, Chu CH. Arresting dentine caries with silver diamine fluoride: What’s behind it? Journal of Dental Research 2018 (epub ahead of print)


Questions and Discussion Thank you! www.appletreedental.org



Presentation Timer Timer: 2:00 to 3:00pm

TOPIC

SPEAKER

TIME (MIN:SEC)

Introduction and thanks to DTAF and 3M

Mike

01:00

1. Science of SDF

Ryan

06:00

2. Practice of SDF -Apple Tree Background

Mike

08:00

-Implementation at Apple Tree

Mike

09:00

-Clinical Cases, Q&A with Dr. Quock

Ryan

05:00

-Evaluation of SDF Outcomes

Ryan

04:00

3. The Promise of SDF and Stories

Mike

06:00

TOTAL GOAL

39:00 40:00

DIFFERENCE

01:00


Notes from July 11…

• 5 minutes: Introductory remarks from OHA • 40 minutes: Formal presentation • 15 minutes: Q&A


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