The 2019 Penn Medicine Benefits Realization report reviews twenty-seven (27) high-profile, high-quality projects implemented in fiscal years 2018 and 2019. The Penn Medicine Information Services (IS) team collaborated with operational and clinical partners to generate substantial financial and qualitative benefits in this year’s report. The projects are grouped into four different categories that define key strategic goals of Penn Medicine: Empowering Technologies, Digital Healthcare, Making Data Meaningful, and Making the Connection.