Introduction ― 4
Selected Projects ― 10
― Federal Research
We know what it means to take pride in your work
Much of the leading research in the country takes place at federal institutions with the greater promise to protect and serve the people. With such great responsibility at hand, we know a space that works just as hard for the cause is equally important.
Evoking the voice and ambitions behind a project is what we love to do; helping to share in creating a platform for the critical exploration happening every day. We know, because for over 80 years, we’ve been designing buildings in which the world’s pioneers thrive. We’d be honored to join you in accomplishing these vital interests. Together, we can create a foundation for your biggest missions.
With 30 studios worldwide, we have an expansive network of people available to you. Our expertise serves clients in nearly every corner of the globe providing a creative knowledge base and industry-specific experience from people who are truly excited about the scope of work.
Words we live by are conducting practice-informed research for a research-informed practice. From developing a tool to help project teams quantify a zoned approach to reducing energy intensity in laboratory buildings, to using a robotic arm to measure ability for precision and automation in construction—we aim to break the mold and provide realworld insights.
The technical demands of today’s science environments require the highest standards of design and expertise. Our active benchmarking tool allows us to not only understand singular building parameters, but also to create custom comparative analysis scenarios, provide the ability to include building performance analysis, and represent the data in easily understood graphic formats.
Client: National Institutes of Health
Size: 10,639 square feet
Completion: 2020
Construction Cost: $25 Million
The Clinical Center (CC) was in urgent need of a new Cell Therapy unit for high risk vector production to serve the Department of Transfusion Medicine (DTM). The Cell Processing Section (CPS), Department of Transfusion Medicine, NIH Clinical Center (CC) is an American Association of Blood Banks (AABB) accredited cellular therapy laboratory whose central mission is to provide services to the NIH Institutes to support their intramural clinical trials. These services include performing research aimed at development, evaluation and validation of new manufacturing processes for cellular therapies and the manufacture of cellular therapy products for approved clinical trials. The products manufactured by the laboratory are used to treat and often cure NIH CC patients with cancer, hematological malignancies, marrow failure, congenital immune disorders and autoimmune diseases.
The DTM project represents a pre-fabricated, modular approach to providing NIH with a FDA-approved cGMP facility to meet their manufacturing needs.
The project includes production distributed among four fully independent laboratories, built with dedicated entry and exit anterooms to mitigate vector cross-contamination. The design concept also provides cryogenic containment for finished products, clean supply storage, administrative and support areas plus other areas and features required for a fully functional, unidirectional flow facility.
Pass through with HEPA
Cyrofreezer Room equipped with environmental monitoring and alarms for containment of products and materials
Client: National Institute of Health Size: 14,200 square feet
The National Cancer Institute (NCI) was in urgent need of a new Tumor Infiltrating Lymphocytes (TIL’s) production facility to serve the NCI surgery branch at NIH’s Bethesda campus. This project relocates the existing NCI TIL’s cGMP facility to a new location, which provides more space for the NCI Surgery Branch and enables them to provide greater throughput of TIL’s cell therapy production. The new manufacturing program as designed and operated in this facility closely complies with the latest FDA requirements and regulations as well as meets all NIH design guidelines as set forth within Chapter 13, Aseptic Facilities, of their 2016 Design Requirements Manual. Toward that end, the design team developed complete User requirement Specifications (URS), Risk Assessment (RA), and a Type C Summary package for FDA review.
The new NCI TIL’s box-in-a-box prefabricated and modular cGMP facility provides 13,200 gross square feet (GSF) including ISO -7 manufacturing suites, lSO-8 support spaces and laboratories, administrative office, and storage areas.
NIH, National Cancer Institute, Tumor Infiltrating Lymphocytes cGMP Lab
Manhattan, Kansas
Client: United States Department of Homeland Security
Size: 708,000 square feet
Completion Date: 2021
― WHAT IT IS It will allow researchers to study foreign animal and emerging diseases in a state-of-the-art facility designed with the highest standards of biosafety and biosecurity.
― WHAT MAKES IT COOL
As a key national asset, NBAF will become the international icon for biocontainment around the world.
“The NBAF will be a key component in our joint effort with USDA to advance research, which is critical to the security of our nation’s food supply and agricultural economy. This critical step also heightens our focus on recently initiated efforts to develop strategic partnerships with both private and public entities in the animal health arena to better leverage the research capabilities of the NBAF once it is operational.”
Under Secretary Dr. Reginald Brothers, Department of Homeland Security, Science and Technology Directorate
Client: U.S. Department of Energy Size: 90,000 square feet
Project, Higher Education, ENR Midwest, 2023
The Integrated Engineering Research Center (IERC) is a new laboratory, technical and office building with a focus on collaboration spaces for the Fermilab scientific and engineering community. The IERC is located to the northeast of historic Wilson Hall and connects directly to the Wilson Hall ground floor and atrium.
With the IERC positioned adjacent to Wilson Hall, it collocates engineering and technical staff in the laboratory’s central campus, which is where most of the scientific user community is located. Wilson Hall is highly valued as an architectural icon within Fermilab and the DOE laboratory community as a whole. While the IERC must also be a signature building, its design requires a sensitive and artful approach to its architectural configuration, scale and proportion in response to this proximity to Wilson Hall. This also complements the ongoing and planned renovations of Wilson Hall and establishes the central campus as the anchor point of the site.
Completion Date: 2023
Awards: Best
The IERC is a new, state-of-the-art building with laboratories equipped to deliver on major initiatives in particle physics. The purpose of the IERC project was to construct a building that provides laboratory space for facilities needed for particle physics detector research, development, and detector construction for the Department of Energy projects.
Bethesda, Maryland
Client: National Institutes of Health (NIH)
Size: 250,000 square feet
Completion Date: 2021
Sustainability: LEED Silver ®
The world’s largest clinical research hospital, known as Building 10, or the Clinical Center.
This conversion is spread over 15 floors in the center of the original 1939 building. The new framework will include clinical program areas, research labs, support spaces, teaching facilities, offices, and building maintenance.
― WHAT MAKES IT COOL
This building generates a major impact on research and outcomes for national health.
Golden, Colorado
Client: United States Geological Survey (USGS) Size: 180,000 square feet
Project Cost: Est. $109 million
Completion Date: Est. 2023
Building on a history of successful collaboration, the Colorado School of Mines and the United States Geological Survey seek to revolutionize Earth Science in the 21st Century by partnering in a new interdisciplinary research facility entitled the Subsurface Frontiers Building. This academic and research focused building will serve as the home for both organizations’ mineral exploration, subsurface energy, and mineral economics programs. The relocation and co-location will provide unique national resources fostering collaborative efforts in the application of geoscience to solve real-world problems including the discovery of sustainable sources of energy, an expansion of potential mineral supplies, and strategies to balance energy, water, and climate for a more sustainable future. ―WHAT MAKES IT COOL United States Geological Survey and Colorado School of Mines seek to
Energy and Minerals Research Facility (EMRF)
Client: National Institutes of Health (NIH)
Size: 320,000 square feet
Completion Date: 2014
Sustainability: LEED Gold ® , Three Green Globes Rating Awards:
Design Honor Award, Over 100,000 SF, IIDA, Mid-Atlantic Chapter, 2015
Award of Excellence, Notable Green Project, U.S. Green Building Council (USGBC), National Capital Region, 2015
― WHAT IT IS
This building co-locates researchers from ten NIH institutes who were previously isolated from one another.
The Porter building is a “game changer,” said NIDCD Scientific Director Andrew Griffith. “The layout is one of the best I have ever seen,” he said. “It both figuratively and literally removes walls between groups.”
Porter
― WHAT MAKES IT COOL
It houses one of the largest MRI devices in the world, at a magnetic strength of 18 Tesla.
The PNRC launched a bold initiative by combining these research institutes in order to increase the pace of discovery in neuroscience and understanding of the human brain. Over 800 scientists in 85 laboratories are all located here.
In addition to solar panels and green roofs, this building is the first to incorporate closed-circuit loop geothermal heat pumps to remove heat loads from the labs and reduce the carbon footprint. Ultimately, the design is 25 percent more energyefficient than a traditional lab building.
Berkeley, California
Client: United States Department of Energy, Lawrence Berkeley National Laboratory
Size: 149,000 square feet
Completion Date: 2015
Sustainability: LEED Gold ®
A high-performance computing and office facility that provides a collaborative work space for faculty, students, and research staff.
Ernest Orlando Lawrence began his lab over 80 years ago by gathering scientists, mathematicians, and engineers to work toward finding answers to the biggest experimental questions of the day. That legacy and inspiration laid the foundation for Berkeley Lab’s success and its latter 13 Nobel Prizes.
― WHAT MAKES IT COOL
Named after a professor who did pioneering work in semiconductor research, it houses one of the world’s leading supercomputer centers.
For more information, contact: scienceandtechnology@perkinswill.com