Three Mechanisms of PQQ (Pyrroloquinoline quinone)

Pyrroloquinoline quinone (pqq) exhibits numerous health benefits throughdifferent mechanisms such as regulation of cellular signaling pathways, gettingrid of free radicals and redox activity.

The pqq mechanisms of action include:

Affects the way genes work

Pyrroloquinoline quinone can affect the way various genes are expressed andespecially the genes involved in mitochondria activity. Its antioxidant activity issaid to be 100 times that of vitamin C.

PQQ supplementation has been shown to activate the CREB and PGC-1asignaling pathways that are directly involved in mitochondria biogenesis.

Acts as an antioxidant

Pyrroloquinoline quinone (pqq) anti-oxidative activity is mainly due to its ability to be reduced to PQQH2 through the reaction with reducing agents such as cysteine, glutathione or nicotinamide adenine dinucleotide phosphate (NADPH).

Inhibits enzymes

Pyrroloquinoline quinone also hinders the enzyme thioredoxin reductase1 (TrxR1), which in turn triggers the Nuclear factor erythroid 2-related factor 2(Nrf2) activities that promotes antioxidant production.

PQQ has also been known to inhibit the development of quinoproteins(damaging proteins) that leads to Parkinson’s disorder.

https://www.phcoker.com/product/108-09-8/ info@phcoker.com