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1. Ganirelix Acetate Description Ganirelix Acetate is the acetate salt form of ganirelix, a synthetic decapeptide with high antagonistic activity against naturally occurring gonadotropin-releasing hormone (GnRH). Ganirelix directly competes with the GnRH for receptor binding in the anterior pituitary gland, thus induces a rapid and reversible suppression of the release of follicle stimulating hormone (FSH) and luteinizing hormone (LH). This agent is used for the inhibition of premature LH surges in women undergoing controlled ovarian hyperstimulation, and in combination with other hormones for retrieval of the mature follicles for in-vitro fertilization.
2. Ganirelix Acetate Specifications Product Name
Ganirelix Acetate
Chemical Name
N-Acetyl-3-(2-naphthalenyl)-D-alanyl-4-c hloro-D-phenylalanyl-3-(3-pyridinyl)-D-al anyl-L-seryl-L-tyrosyl-N6-[bis(ethylamino) methylene]-D-lysyl-L-leucyl-N6-[bis(ethyl amino)methylene]-L-lysyl-L-prolyl-D-alan inamide diacetate
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Brand Name
Orgalutran, Antagon
Drug Class
Peptide
CAS Number
129311-55-3
InChIKey
OVBICQMTCPFEBS-SATRDZAXSA-N
Molecular Formula
C84H121ClN18O17
Molecular Weight
1690.45
Monoisotopic Mass
1688.8845622
Melting Point
N/A
Biological Half-Life
N/A
Color
White
Solubility
0.25mg/ml~30mg/ml in DMSO and DMF
Storage Temperature
−20°C
Application
used for the inhibition of premature LH surges in women undergoing controlled ovarian
hyperstimulation,
and
in
combination with other hormones for retrieval of the mature follicles for in-vitro fertilization.
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3. Buy Ganirelix Acetate powder
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