1.WhatisBPC-157(137525-51-0)?
BPC-157,alsocalledPL14736,PL10,andPLD-116,isoneofmanypeptidesavailableonthe supplementmarket.However,whatsetsitapartfromitscompetitorsisthefactthatit’sextractedfroma gastrointestinalprotectiveprotein
BPC-157isapentadecapeptidewhichisacompositionof15aminoacidsfoundinhumangastricjuiceIt hasbeendiscoveredthatBPC-157playsasignificantrolewhenitcomestohealingvariouswounds sufferedbythebodybutmostlyithasshownnoticeableresultsinhealingtendonThisisaproteinbooster thatwasinitiallymadetohelpwithinflammatoryboweldiseaseaswellasgastriculcersHowever,with consistentresearchithasbeenestablishedthatthehealingpropertiesofBPC-157arenotlimitedand theycanalsohelpwithintestinalre-sectioninginadditiontoreattachingmuscletotendon
AlthoughadditionalresearchneedstobeconductedinordertoconfirmBPC-157’sabilitytohealmultiple levelsofthebody,there’senoughevidencetoconfirmthatithasapositiveeffectonangiogenesisgrowth factorsAngiogenesisreferstotheprocessthroughwhichbloodvesselsaredevelopedinthebodyandit playsanimportantroleinhealingdamagedtissue.
2.WhatdoesBPC-157workonbody?
ResearchonBPC-157(137525-51-0)hasbeenon-goingsince1991andresultsthereofindicatethatthe peptidehastheabilitytorepairdamagedteeth,bones,muscles,tendons,andevenintestinesThisdata isbasedonin-vitrolabtestsaswellasin-vivostudiesconductedonbothrodentsandhumansSomeof thehumantrialsinvolvedinjectingthepeptideundertheskin(subcutaneously)andintothemuscles (intramuscularly)
ScientistsrecognizeBPC-157asa“stablegastricpentadecapeptide”,duetoitsabilitytobringequilibrium tohumangastricjuice.Ithasalsobeenshowntotreatulcers,healinflammatoryboweldiseaseaswellas theupperandlowerGItractwithremarkableefficiencyThebestpartisthatBPC-157doesn’tcomewith anyadverseside-effects!
TheabovementionedstudiesallindicatethatBPC-157worksgreatwhenitcomestofast-trackingwound healingThroughitspositiveinteractionwiththeNitricOxide(NO)system,BPC-157helpshealwounds bybuildingupthebloodvesselsandprotectingtheendothelialtissueItalsopromotesgeneexpression whilespecificallytargetinggenesthatareresponsibleforcollagenformation,generationofgrowthfactor andcytokineItcanalsohealintestinalanastomosisandshortbowelsyndromeAllofthe abovementionedconditionsareknowntoaffectsufferersofbowelinflammation,diarrhea,constipation, andgutpainThesepositiveeffectshavebeenobservedeveninconditionsthathadreachedadvanced stages
Phcoker
3.BPC-157Benefits
▪RepairsTheBrain
▪ProtectsAgainstDrug-InducedDamage
▪RestoresTheSerotogenicTransportSystem
▪ProtectsDopaminergicSystem
▪EnhancesTheGABAergicSystem
▪ReversesOpioidTolerance
▪ProtectsTheHeart
▪AcceleratesBodyRepair
▪HelpsWithAllergiesAndViruses
▪MayHelpIrritableBowelDisease
▪HelpsWithOcularDysfunction
▪MayHelpOralCavity
▪MayHelpWithUrinaryIncontinence
4.BPC-157applicationinthemarket
(1)BPC-157forBodyBuilding
ThemostimportantrolethatBPC-157playsisinthebodybuildingThemaintissueresponsiblefor collagenproductionandangiogenesisisthegranulationtissueVesselformationorangiogenesiscan slowdownincaseofinjuryoragingUsually,asbodybuildersgrowold,theyneedsupportforthe restorationoftheprocessofangiogenesisandthereforeBPC-157isusedAsestablished,BPC-157 containshighlevelofhealingpropertiesformusclesandjointswhichrelievespainthatisexperiencedby bodybuildersandheavyliftersManyofthemhavepersonallytestifiedthatthismedicinalsupplementhas beeneffectiveineliminatingthepain
(2)BPC-157inSupplements
Phcoker
BPC-157isnotarecentdrugbutduetoitssyntheticnatureithasnotbeenwidelyusedinthepast However,itisstartingtomakeitsappearanceintheworldofsupplementsAlthough,itisnot independentlyusedasasupplement,itisusedasaningredientinafewofjointsupportdietary supplements.Itisnotonlybeneficialinrelationtoprovidingrestorationofbonesandmusclesbutalso preventionfromvariousrelateddiseases
AnotherimportantfactoraboutBPC-157isthatsinceitreducesjointpain,itcanalsobeusedbyelderly peoplewhoaremoreaccustomedtoundergobodyaches.Itwillhelponcontrollingthepainthatis causedbyanagingbody
5.ShareexprienceafteruseBPC-157
IoriginallyuseBPC-157formybiliarysystemandleakygut,butfoundittohaveothersystemiceffects I'veonlytakenitorallyandsublinguallyandithashelpedmewithmysleep,cognition,andfood intolerancesIonlyneedverylittledoses(~50mcg)I'vealsonoticedincreasehistamineinmygutfromit (couldbepartoftherepairprocess)Iwillbetryingitsoonformyblood-brainbarrierissueswithCIRS (intranasallyorinjected)
SomepeopleIknowhavetakenitintranasallyorcorneally(aseyedrops)andithasworkedOthershave reporteditsignificantlyhelpingtheirworkouts,spinalinjuries,anhedonia,depression,IBS,anxiety,and PostOrgasmicIllnessSyndrome(tonameafew)
Here'smyspeculationandwhatIhopetoseeresearchin:IwouldlovetoknowhowBPC-157workson tightjunctionsinthegutandzonulin-1(ZO-1)orit'seffectonthemicrobiome/microbialbyproductsand peptidesasitseemstoreversealotofdysbiosis-relateddisorders.
6.HowtouseBPC-157?
BPC-157canbetakenthroughtwomethods:
♣Injections
♣Orally
Therearetwotypesofinjectingmethods:intramuscularandsubcutaneousIntramuscularinjectionis appliednearthemusclewhichispain.Byinjectingitdeeplyinsidethemuscleyouwillbeabletoprovide BPC-157toyourbodyforhealingTheothermethodissubcutaneousinjectionwhichisappliedunderthe skin.Bothofthemareusefulinjectingmethods.
Whenitcomestotakingitorally,yousimplyhavetospraythecompoundinyourmouththroughthe syringeThismethodshouldbeperformedwithpropercaretoavoidanymouthinjuries
(1)BPC-157Injection
HowtogettheBPC-157online?
YoucanbuyBPC-157atafewdifferentpeptidesuppliersontheinternet.I’llwarnyou:kindoflikeonline pharmacies,thewebsitesarecheesy,andtheytechnicallyaren’tallowedtoselloradvertisethesekindof peptidesassomethingappropriateforhumanconsumptionorhumaninjection,butyoucanprettyeasily finditandbuyBPC-157ifyouknowhowtouseyourGooglingskillsproperly
Ican’tethicallysayanyoftheseformsofBPC-157are“superior”sincenoneofitistechnicallylegaltosell forhumanuse(you’llnoticeeachsitespecifiesthatitisforlaboratorychemicalresearchonly)butfigured I’dgiveyouafewchoicesincaseoneofthewebsitesaboveisoutofstockatthetimeyouhappentobe readingthisarticle
Forreasonsyou’reabouttodiscover,IalsobuyBPC-157fromPhcokerandgetgoodresults
WhatdoyouneedtodobeforeinjectBPC-157?
①Oneboxofinsulinsyringes,preferably1ml/1cc,with28gauge1/2inchattachedneedles(theslang
Phcoker wwwphcokercom
termforthesesyringes),amongself-injectorsofpeptidesandhormones,isa“slinpin”
②One30mlbottleofbacteriostaticwater
③Onepackageofalcoholcleaningwipes
HowtomixBPC-157?
①PopthecapsoffboththeBPC-157andBAC
②GentlyalcoholswabtherubberstopperontheBPC-157,thenletitdrySamegoeswiththeBACvial
③DoseoutthecorrectamountofBACInthecaseofa30mlbottleofBAC,ifyoufillthreeinsulin syringesfullofwater,thenveryslowlyandcarefully(peptidesareextremelyfragile)injecteachofthose syringesintoa5mgbottleofBPC-157,youaregoingtonearlycompletelyfillthe5mgbottleofBPC-157.
④Oncethe5mgbottleofBPC-157isfull,thenbasedonthisveryhandyPeptideMixing&Dosing Calculator,eachtimeyouinjecta1ml/1ccsyringeintoitandpullthatsyringebacktothefifteenthtick mark,youaregoingtohaveyourselfapproximately250mcgofBPC-157
Beforeandafterreconstitution,keepyourBPC-157awayfromUVrays,sunlightandheat.Itwillremain stableatroomtemperatureforuptotenweeks,butforbeststorageandresults,youshouldstoreinyour refrigerator,inwhichcaseitwillstaystableforuptosixmonths.Itwillstaystableinafreezerforuptotwo years
ThestuffissuperfragileIcannotemphasizeenoughtheimportanceofveryslowandpatient reconstitution.WhenyouspraytheBACintotheBPC,aimforthesidesoftheBPCbottle,anddon’tspray directlyontotheBPCpowderitselfWhenyoudrawtheBPCupintothesyringeforinjectionororaluse, turnthebottleofBPCupsidedownverycarefullyandthendrawtheliquidupintothesyringeveryslowly Whenyouinjectitorsprayitintoyourmouth,injectitveryslowlyIfyoukeepitintherefrigerator,keepit awayfromthingsthatmightknockitoverorjostleitaround
HowtoinjectBPC-157?
♦
Thesubcutaneousmethodistheeasiestandleastpainfulbecauseitinvolvesinsertingtheinjectionunder theskin,preferablyinanareaasclosetotheinjuryorpain-pointaspossible
♦Intramuscularinjection
Alternatively,youcaninjectBPC-157intramuscularly,whichmeansstabbingtheneedlerightintothe muscleNeedlesstosay,thisisaverypainfulmethod,especiallywhenyouconsiderthatit’stypically doneinanareathat’sclosetotheinjuryaswell
♦SprayBPC-157intoyourmouth
ByfartheeasiestmethodistospraythepeptideintoyourmouthJustmakesuretoholdtheliquidinside yourmouthforabout90to120secondsbeforeswallowing.
Ifyou’reokaywithneedlesthenyoucanalwaysoptforasubcutaneousneedleinstead.Allyouhavetodo ispinchanareaoftheskinascloseaspossibletotheinjury,makingsuretoangletheneedlesothatit sortof“slips”underneaththeareaoftheskinthatyou’vepinchedandnotdirectlyontoit.Thiscanbeabit difficulttodosoitmightbeagoodideatogetsomeonetohelpyououtwithitRemembertousean alcoholswabtocleantheareaoftheskinthatyou’reabouttoinject,aswellastherubberstopperbefore andaftertheinjection
ThemostpainfulyetequallyeffectivemethodthatyoucanchooseistheintramuscularinjectionSimilar tosubcutaneousinjections,thismethodrequiresthatyoucleantherubberstopperandthepartoftheskin thatyou’reabouttoinjectwithanalcoholswabHowever,you’llbestabbingtheskinwiththeneedle insteadofworkingitinlikeyouwouldwiththesubcutaneousmethodKeepinmindthatyou’llbe administeringtheneedleasclosetotheaffectedareaaspossible,whichmightaddtothepainBut, thinkinghappythoughtshavebeenshowntohelpinsomeinstancesalthoughwecan’tguaranteethe efficacyofthatmethodOnthebrightside,thismethodwillenablethepeptidetoworkquicklyand acceleratehealing
(2)OralBPC-157
OralBPC-157:TheeffectiveBPC-157dosage
Itisimportanttokeepinmindthatitisstillarecentmedicinalcompoundthatisbecomingcommonwith timeThisiswhythedosageisnotsetbutmerelyestimatedItisrecommendedthatthatapersonwho weighs250lbscantake180ug,110ugfor200lbsofweightand6ugfor150lbsItisrecommendedto takeaprescribeddosagetocompleteyourcycle
7.WarningonBPC-157
BPC-157hasbeenshowntobesafeinclinicaltrialsforinflammatoryboweldisease(PL14736),safefor intestinalanstomosistherapy,andiscurrentlyinclinicaltrialsformultiplesclerosis
Inmoststudies,BPC157exhibitsarapid,beneficialeffect(sincethefirstday)onacellular
levelCoritcosteroidsmayreduceBPC-157'sabilitytohealmusclesAsitisproangiogenic,itcould enhancegrowthofcancerSameofmostofdrugs,BPC-157warningneedtobetakenseriously
8.Summarize
Afterreadingthearticle,you’reprobablywonderingtoyourselfwhyno-onehastoldyouaboutthis incrediblyhealingpeptideyet.
OneoftheproblemsisthatBPC-157(137525-51-0)isnotpatentablewhichmeansthepharmaceutical industrycannotmakemoneyfromitEvenyourdoctorprobablydoesn’tknowaboutitbecauseit’snot beingmarketed,andsinceit’snotregulatedbytheFDA,BPC-157technicallyisn’tallowedtobesoldfor humanuseAndthisisregardlessofthefactthatBPC-157isanaturalgastricjuicepeptide
ThegoodnewsisthatBPC-157hasn’tbeenbannedbysportsgoverningbodieslikeWADAandUSADA ThismeansthatathletesandbodybuilderscanstilltakeitandbenefitfromitshealingpropertiesButthe lackoflong-termhumanstudiesonBPC-157meansthere’sapossibilityofitbecomingprohibitedby thesegoverningbodiesinthefuture
Nevertheless,BPC-157isprettysafetotake,asnoadversesideeffectshavebeenshowninthe short-termclinicaltrialsthathavebeenconductedsofarSoifyouhaveaproblemwithgutinflammation, injuriesoranyoftheconditionsmentionedinthisarticle,thenyoumightwanttoconsideritasaformof treatment