Phcoker
www.phcoker.com
How does avanafil work? Side effect,dosage,Risks & Reveiws CAS# 330784-47-9 Reproduce from： https://www.phcoker.com/ask-yourself-before-taking-avanafil/
1. What is Avanafil (330784-47-9)?........................................................................................................ 2 2. Avanafil video..................................................................................................................................... 3 3. What causes erectile dysfunction?.....................................................................................................3 Physical causes of erectile dysfunction .......................................................................................... 4 Psychological causes........................................................................................................................4 4. Avanafil Works — What is avanafil used for?.....................................................................................4 5. Avanafil Dosage – How much Avanafil should I take?........................................................................5 6. Avanafil Results — How to take Avanafil for maximum benefits?..................................................... 6 Take note of the following before taking the Avanafil dose：........................................................7 Who should not use Avanafil?.........................................................................................................8 Who should take Avanafil with caution?.........................................................................................9 7. Avanafil side effects – could Avanafil give me side effects?...............................................................9 8. Avanafil Risks — What other drugs will effect avanafil?.................................................................. 10 9. Avanafil Reviews — Is Avanafil a safe ED drug?............................................................................... 12 10. Storage and disposal safety............................................................................................................ 13 11. Avanafil Powder Supplier — Where can I get the Avanafil (330784-47-9)?.................................. 14 12. Avanafil Compared to Tadalafil and Sildenafil Citrate for ED Treatment....................................... 15 So how fast are the drugs and how long is their effect?...............................................................15 a. Avanafil (330784-47-9)................................................................................................... 15 b. Sildenafil (139755-83-2)................................................................................................. 16 c. Tadalafil (171596-29-5)................................................................................................... 16 13. 【References】............................................................................................................................. 16
1
info@phcoker.com
Phcoker
www.phcoker.com
Avanafil dosage is the latest medication in the medical field that treats erectile dysfunction in men. The cases of sexual impotence in men have been on the rise in recent years. The condition makes it hard for men to satisfy their partners since their sexual organs do not harden enough and if they do it’s only for a short time. Typically, when a man gets aroused, the blood will flow to the penis enlarging it for successful intercourse. However, when suffering from erectile dysfunction (ED), you will have difficulties in your sexual life. Avanafil works by enhancing blood flow into your penis to sustain an erection for a reasonable time. Medical researchers have been trying to find various medications to help the situation which has resulted to development of multiple drugs such as Viagra, Tadalafil, Sildenafil and now Avanafil. Erectile dysfunction is a problem that lowers one’s self-esteem and has even been a significant cause of divorces in our society. Avanafil is the solution to all your erection problems. The drug will help you maintain your erection for a reasonable time by preserving blood flow into your penis. Nevertheless, for the drug to work, you must first get aroused and get the blood flowing to your penis. For those who have been using this drug after its approval, have given positive feedback and an excellent rating providing hope to those who are yet to try it. As a precaution, before purchasing any drug not only the Avanafil, you need to do some research and understand how it works. Drugs react differently to different people, and a drug that helped your friend might cause health complication to your body. Therefore, it’s advisable to involve your doctor to help you get the right drug and proper dosage after examining your immunity. Interestingly, some people get an average erection while others get maximum results after using the Avanafil. There are also those who are forced to take high dosage for them to get the results they desire. Some medical conditions might limit the options you have for the erectile dysfunction drugs available on the market.
1. What is Avanafil (330784-47-9)? Avanafil is an oral medicine that has proved to be useful in the treatment of erectile dysfunction. The drug belongs to phosphodiesterase inhibitors a class of drugs that have other medication such as Viagra, Cialis, and Levitra. Avanafil which sales in the united states of America as Stendra, was approved by the US Food and Drug Administration on April 27th, 2012 after some years of study. The Avanafil dosage strengths approved are of 50 mg, 100 mg, and 200 mg. However, a patient should be prescribed to use the lowest dose available at first to avoid severe side effects. Avanafil was approved after being taken through three different trials where the drug proved to be ideal and worked for all men used in the test. An application to market the drug in Europe was submitted to the European Union in March 2012. The medication is now selling in South Korea under a different brand after the state relevant agencies approved it. Determining the levels of erectile dysfunction can be a challenge due to the failure of the majority of men to report the problem during surveys. According to various studies, sexual impotence
2
info@phcoker.com
Phcoker www.phcoker.com increases with the increase in age. That means the older people are likely to experience the problem than the middle-aged and the young ones. For instance, men aged between 18 to 59 years have an impotence rate of 10%. Another similar study found out that men aged 50-59 had a 3.5% higher rate of erection dysfunction than individuals ranging between 18-29 years of age. The people aged 70 years and above have a 61% rate of erectile dysfunction.
2. Avanafil video https://youtu.be/mvZDe7NFMvU
3. What causes erectile dysfunction? Male sexual arousal is a process that involves the coordination of various body organs and tissues such as brain, emotions, hormones, muscles, nerves and blood vessels. In case one of the parts has a problem can result in erectile dysfunction. On the other hand, mental health problem or stress can worsen the situation, and it’s one of the leading causes of sexual difficulties in both men and women. In many cases, the combination of psychological and physical issues lead to erectile dysfunction. A small physical condition which slows down the sexual response can lead to anxiety making it difficult for you to maintain an erection. Sometimes people don’t notice the problems that lead to erection difficulties and opt to keep it a secret until the situation worsens.
3
info@phcoker.com
Phcoker
www.phcoker.com
Physical causes of erectile dysfunction Some physical body factors are responsible for the difficulties in erection, and they are as follows;
Heart disease, your heart is responsible for pumping blood to various parts of your body including your penis. In case the heart is not in good condition, you will have difficulties in maintaining your erection. For you to experience a proper erection, your heart must be healthy to keep a continuous flow of blood during sexual arousal. Atherosclerosis (clogged blood vessels), when your heart is pumping blood, and the vessels don’t allow it to reach various parts of your body; it can result to multiple problems apart from erectile dysfunction. Therefore, if your blood vessels are clogged or thin due to piling of fats on the walls, your penis will not receive enough blood to harden enough for successful sex. A proper health examination will be important to determine the real cause of your problem before the doctor recommends you to take Avanafil. Prostate cancer treatment or enlarged prostate, sometimes men feel that their male organ is not large enough and decide to go for manhood enlargement surgery or use supplements. Your heart can’t supply enough blood to an extra organ apart from the natural ones. Prostate cancer also affects the sexual organ veins and hormones that increase sexual stimulation. Substance abuse and alcoholism have been cited as another major cause of erectile dysfunction. You can work on reducing the intake of alcohol as you consider using Avanafil. Regular exercises are also an excellent remedy for burning the extra fats in the body and keeping your heart healthy.
Psychological causes Your brain plays an essential role in initiating a series of events which lead to erection such as triggering feelings and sexual excitement. In case you’re thinking of something else, be sure it will interfere with your erection. Some of the psychological causes of arousal difficulties include depression, stress, and anxiety among other mental issues. If you are experiencing relationship problems, then you will have erectile difficulties either your partner since your mind is not in a good state. The moment your brain if focusing on other issues rather than thinking about your sexual experience with your partner, the erection will be a problem.
4. Avanafil Works — What is avanafil used for? This drug works by preventing the action of phosphodiesterase type 5. Erection is a product of a series of activities involving nervous system signals and release of chemical signals in the penis tissues. The chemical messengers in your penis include Cyclic GMP which causes the penis blood vessels to widen by relaxing the muscle layer in the blood vessel walls. Thus, allowing blood to flow into your sexual organ making it erect and become hard after the blood fills the penis blood vessels. The phosphodiesterase type 5 that is present in the penis breaks down the Cyclic GMP functioning, thus blocking the flow of more blood. That means the blood flow to your sexual organ will not be enough causing the penis to shrink. Avanafil (330784-47-9) stops the phosphodiesterase from
4
info@phcoker.com
Phcoker www.phcoker.com acting, to stop any cyclic GMP interference, thus improving the blood flow into your penis. Therefore, being able to have an erection for a longer time and satisfy yourself and your partner. The drug also enhances the proper functioning of chemical messengers that are responsible for facilitating erection. Avanafil will only be effective if the chemical messengers are present. Consequently, you have been sexually stimulated for the drug to help you maintain the erection. You should take the Avanafil dose thirty minutes before you intend to have sex for better results. In the United States of America, the Avanafil is sales under the brand Stendra. The product is just the same only that it has different brand names in different countries.
5. Avanafil Dosage – How much Avanafil should I take? Just like any other medication, you should make sure you take the right Avanafil dosage to get the desired results. Consult your doctor before going to the market to purchase Avanafil. The drug comes in different forms such as powder and pills. It is advisable to take Stendra at least 30 minutes before you engage in sexual activity. You will start experiencing the Avanafil results after about 20-40 minutes upon taking the Avanafil. In some cases, the results might delay depending on various factors or your body strength. When it happens, don’t rush to take another dose, consult your doctor to guide you on what to do next. Remember, it’s not advisable to take two doses a day, it can be risky or result to severe side effects such as getting an erection for a very long time or headaches. The standard Stendra dosage is 100mg per day. However, if you feel it’s not effective, your doctor can increase it to the maximum dosage of 200mg. The doctor can recommend a reduction of the dosage by 50mg, in case you are experiencing side effects with the main dosages or you are under medication for other diseases. Avanafil should be taken before you take your meals for quick results. Taking the dosage after meals can delay its effect for some time which is normal. You should swallow your Stendra tablet with a glass of water. Avoid drinking grapefruit juice 24 hours before taking the drug. It could increase the level of this drug in your blood leading to severe side effects. Some people might decide to take medicine using other drinks such as soft drinks or milk which is not advisable. Stick to using water for effective results and to avoid any adverse effects. As much as you need to have maximum sexual pleasure, stick to one dosage as prescribed by your doctor.
5
info@phcoker.com
Phcoker
www.phcoker.com
6. Avanafil Results — How to take Avanafil for maximum benefits? The drug guarantees excellent results so long as you follow your doctor’s prescription. Don’t purchase the drug without letting your doctor examine your health condition and allowing him/her to advise you accordingly. Taking extra dose than it’s recommended can lead to uncontrollable erections or other severe side effects. Make sure you are always on the safe side by following the doctor’s advice and in case you feel the dosage is not enough, consult the doctor for further instructions. People react differently to drugs, and just because the drug manufacturer assures you of results in 20 minutes, it’s possible for the results to delay or even come early than you expect. Body strength is key in determining the effectiveness of the drug even if you follow all the doctor’s instructions. For instance, some people can get maximum results and long erections for just taking the 100mg dose while others will have to increase the dose to get the effects they desire. In other cases, the doctor will be forced to reduce the standard dosage if the patient suffers from side effects by taking the normal Avanafil dose of 100gm per day. In case you are under medication for other diseases go medical examination first to determine if the Avanafil will be safe to use with other drugs. The doctor will design the drug dosage that will be perfect according to your condition.
6
info@phcoker.com
Phcoker www.phcoker.com Watch out for counterfeit Avanafil drugs that might be available on the market since they can be riskier. They can cause more harm to your body instead of helping you achieve the erection levels you desire to save your sex life. Get the drug from a reputable seller or get it from your nearest clinic under the guidance of your doctor. Look for the quality label and read the usage instructions carefully for you to enjoy the maximum benefits.
Take note of the following before taking the Avanafil dose： Avanafil can cause visual disturbances and dizziness. To be on safe side, you should be aware of this reactions although they vary from one person to another. In case you feel dizzy after taking the drug, sleep for some minutes, and the effects will go away. Taking this medicine with alcohol increases the chances of dropping the blood pressure which may make you faint or feel dizzy. Drinking alcohol and then take your Avanafil dose might weaken your sexual performance. When your erections last for more than four hours after taking the drug, reach to your doctor immediately. The condition should be treated within six hours of erection since more delays can lead to damage of the penis erectile tissues or irreversible erectile problems. For those who experience loss of sight in either one or both eyes, should stop the intake of the drug and reach out to a doctor within the shortest time possible. There are other problems you might experience, especially if you are a first-time Avanafil user such as a slight headache, or even delay in getting results. These are common effects due to the reaction of your body, but they go away after some minutes. In the event the effects persist for more than 30 minutes, call your doctor to help in controlling the situation. Don’t take the drug while at work or when you are driving. The effects could be severe and result in an accident. Always ensure your partner is near and is also ready for sex before taking the drug. The effects can be severe if you take the Avanafil dose, get aroused and fail to have sex. You will be exposing your penis muscles to damage which can make your erectile problems worse. Remember, the drug enhances blood flow into your penis muscles, and if the organ doesn’t do its work, the erectile tissues will be stretched beyond the maximum levels which are very dangerous. Your doctor can reverse the situation if you call him/her in time after you notice you might not engage in sex after using the Avanafil due to one reason or another. Some people think of taking another dose if they don’t get results within the 40 minutes time frame given by the experts. You should understand that the results might delay if you don’t get sexual arousal or you took the drug after meals. Your stomach should be empty, if you need fast results and also ensure you get sex arousal soon after taking your dose. Don’t expect any results when you are not in the sex mood. Your brain should be ready for the act together with other involved body hormones. The drug only helps in maintaining an erection for a more extended period by enhancing the blood flow into your sexual organ.
7
info@phcoker.com
Phcoker
www.phcoker.com
Who should not use Avanafil? Although these generic ed drugs are excellent for helping men with erection problems, it should be used by specific people. Not everybody can use this drug; for instance, the Stendra is not made for women. However, it’s not clear when can happen if a woman uses the drug, but it’s only explicitly made to help men maintain their erection. Children are also not allowed to use Avanafil since their bodies are not strong enough to sustain the reaction of this drug. Those in adolescent or under 18 years old are also prohibited from using the drug. Some men should not consider using this drug especially those suffering from complicated diseases such as kidney failure, unstable angina, low blood pressure, and high blood pressure among others. Your doctor should examine your health condition before recommending the right Avanafil dosage. If you have any condition that you were advised by a doctor to stay away from sex, then you should not use this drug as well. Heart problem is another disease that should stop you from using the drug. Avanafil enhances blood flow, which means your heart will be forced to pump the blood harder and if you have any heart disease, using Avanafil could worsen the condition. For men who have ever had an eye disease known as non-arteritic anterior ischemic optic neuropathy (NAION) should also stay away from this drug. The disease causes partial loss of sight since it damages the optic nerve. In some cases, the patients can lose vision in one or both eyes, and the condition can be permanent, or if you get quality treatment on time, the condition can be temporary. Inform your doctor if you once suffered from this sickness. One of the body reactions you will experience after taking Avanafil is a loss of vision for some time. Thus, if you had the problem before, it could revive the sickness or make it worse. Look at the ingredients if you are allergic to any, then try other erection dysfunction medication methods. Sometimes after taking the drug is when you experience the allergies, inform your doctor or pharmacist before getting another dose. It could be advisable to stop using the Stendra once you notice you’re allergic. However, some allergies can be controlled reach out to your doctor to know if the allergy can be controlled before you stop using the Avanafil completely. Additionally, ii in the last six months, you have been experiencing abnormal heartbeat, then consider other erectile dysfunction medications. Don’t take the Avanafil with other PDE5 inhibitors such as tadalafil, vardenafil or sildenafil. All the drugs work in almost the same way and taking them at once means you are overdosing which can increase the side effects. The Stendra doesn’t protect you from sexually transmitted diseases like HIV & AIDS. Therefore, use protective gears after taking the drug as it only enables you to erect for a longer time. Inform your doctor if you have had any surgery in the last few months since it might compromise the recovery progress. In summary, visit your doctor for a health examination and get professional advice on the right dose to use. Many people rush into pharmacies to purchase the drug even before consulting a doctor which is very risky. Majority of men who take the Avanafil without doctor’s advice, they have high chances of experiencing severe side effects. 8
info@phcoker.com
Phcoker
www.phcoker.com
Who should take Avanafil with caution?
Avanafil is a powerful drug which demands to be taken with caution by some people. For instance, men above 70 years old should be cautious when using the drug. The body strength goes down as you age. Taking Avanafil dose that is beyond your body strength can be very dangerous, and the reactions can be severe than expected. Instead for getting the arousal you desire, you might end up spending some time in a hospital treating the side effects.
In case you have a liver problem then you need to watch the Avanafil doses you take. Let your doctor understand the problem and can reduce your dose by 50gm or more after health diagnosis.
Men suffering from blood disorder such as hemophilia or those with an active peptic ulcer. Other conditions that require men to take Avanafil carefully is when one is suffering from leukemia which can lead to prolonged erections. And those with physically abnormal penises like the severe curvature, and scarring.
Men who have suffered a stroke, a heart attack or arrhythmia (an irregular and life-threatening heartbeat) in the past six months. It should also not be consumed by men who are suffering from heart failure.
7. Avanafil side effects – could Avanafil give me side effects? Medicine is a combination of chemicals and other substances that may not always agree with all bodies all the time. Most drugs have their side effects, and Avanafil is not any different, and this is why we are informing you of the side effects so you can be vigilant and prepared when using the drug. Some of the side effects that come along with using Avanafil include those listed below and just because a side effect is named below it does not mean that it has to happen to you.
Dizziness – the use of Avanafil could make you dizzy and sluggish therefore it is essential always to ensure that you are perfectly fine before attempting to operate any machine or driving. In the case where you feel woozy or faint after taking this drug, it is advisable that you lay down for a while until these symptoms go away. Priapism – this means that sometime the erection might last longer than it should. If your erection lasts for more than four hours, you should consult a medic immediately. Not seeking treatment in less than six hours of the priapism could be fatal. This is because it can cause severe damage to the erectile tissues found in the penis which in turn would cause permanent erectile dysfunction. Blurred vision – in rare occasions Avanafil may cause loss or decreased sense of sight in one eye or even both. If this occurs, you should cease using the drug and see your doctor immediately. Hearing problems – if you experience an abrupt reduction or loss of hearing you should discontinue using the drug and seek medical attention as soon as possible. Getting an erection without any sexual incentive whatsoever and passing urine more frequently than normal plus itching in the genital area. It may also cause premature ejaculation. Tummy issues – these issues range from problems with the gut and diarrhea, pain in the lower abdomen, inflammation in the stomach ‘gastritis’ and indigestion. 9
info@phcoker.com
Phcoker
www.phcoker.com
Increased levels of prostate-specific antigen (PSA) and bilirubin and creatinine in the blood. Blood pressure – in people who use alcohol the drug will cause a decrease in the blood pressure while it may also increase the blood pressure in non-alcoholics. Peripheral edema – due to excess retention of fluids the legs and ankles may swell. It may also cause pain in the muscles and spasms.
Other sides effects include; chest pain, weight gain, heart murmurs, seasonal allergies, back pain muscle tightness, abnormal heart rhythm, sinus congestion and headache, increased liver enzymes, hot flushes, insomnia, sleepiness and fatigue, palpitations, tachycardia, and inflammation of the nose and throat, causing a blocked or running nose and sore throat. Avanafil may have other side effects it is therefore imperative that you talk to your doctor if you start undergoing significant body transformations or discomfort while you are on the drug. Some patients experienced these symptoms after they took Avanafil and some who ignored them ended up having permanent problems such as loss of vision. Other people had the symptoms and stopped using Avanafil, and instead, they started using similar drugs which is not very healthy.
8. Avanafil Risks — What other drugs will effect avanafil? Like I said medicine are chemical substances and chemicals react with other compounds. The reaction could give positive or negative results this is why it is very important to inform your doctor or pharmacist about any other drugs that you may be taking and these include those that you bought over the counter or even herbal medicine. Similarly, before starting to take new medications while you are on Avanafil, it is vital to check with your doctor to ensure that the drugs are compatible. Avanafil is not compatible with any form of nitrate medicine, and this means that they must never be taken alongside each other. This is because mixing the two may lead to a severe fall in blood pressure which in turn will cause dizziness, fainting and in the worst of cases a heart attack. If a nitrate must be given to an individual who has taken Avanafil, it must not be before 12 hours have gone by after he consumed the dose of Avanafil. Nitrate combinations include:
Amyl nitrate Nicorandil Glyceryl trinitrate, isosorbide mononitrate (Imdur, Ismo, Monoket), and isosorbide dinitrate (Isordil).
These drugs are used to treat angina or heart failure. In the case where you get chest pains as a side effect of using Avanafil, you should not use any nitrate to treat it. Men who are using the drugs listed below should also avoid using Avanafil because they reduce the breakdown of Avanafil in the body hence increasing the chances of its side effects occurring. These drugs include:
10
info@phcoker.com
Phcoker
www.phcoker.com
Atazanavir (Reyataz) Clarithromycin ( Biaxin) Indinavir (Crixivan) Itraconazole ( Sporanox) Ketoconazole (Nizoral) Nefazodone Nelfinavir (Viracept) Ritonavir (Norvir) Saquinavir (Invirase) Telithromycin (Ketek)
You should also avoid using Avanafil alongside other drugs used to treat erectile dysfunction. The safety of using this drugs together is yet to be proven. Also, people who are using alpha-blockers should avoid taking Avanafil as the combination may lead to higher chances of a fall in blood pressure which in turn will increase the chances of fainting and wooziness. People who take alpha-blockers must be put on a stable dose of alpha-blockers before the Avanafil is started. In such instances, the Avanafil must be started at a dosage of 50mg. If the person was already on Avanafil and there is a pressing need for the patient to be placed on alpha-blockers, then the alpha-blocker should be started on the lowest dose possible. The following are some of the alpha-blockers:
Alfuzosin Doxazosin Indoramin Prazosin Tamsulosin Terazosin (Hytrin)
People who are on medication for high blood pressure should also be vigilant when using Avanafil. Combining antihypertensive with Avanafil may lead to an additional drop in blood pressure. This drop may not be of much importance, but it has the potential of causing dizziness due to the increased drop in blood pressure. If this happens, it is essential to share the information with your doctor. The medicines listed below could raise the blood level of Avanafil. In case you are consuming any of these drugs it very critical that you do not have more than the 100mg intake of Avanafil and the doses should be consumed with time gaps of 48 hours between the doses. These drugs are:
Amprenavir Aprepitant Diltiazem Erythromycin Fluconazole Fosamprenavir Verapamil
11
info@phcoker.com
Phcoker www.phcoker.com Some medications also can reduce the effectiveness of Avanafil. This is achieved by their ability to speed up the breakdown of Avanafil. These drugs include:
Bosentan Carbamazepine Efavirenz Phenobarbital Rifampicin
Avanafil must also not be used together with other PDE5 inhibitors that are used to treat impotence. Examples of such drugs include:
Vardenafil also known as Levitra Sildenafil is commonly known as Viagra
9. Avanafil Reviews — Is Avanafil a safe ED drug? On the 27th of April 2012, The FDA approved Avanafil as a safe drug to be used by men who are suffering from erectile dysfunction. “This approval expands the available treatment options to men experiencing erectile dysfunction, and enables patients, in consultation with their doctor, to choose the most appropriate treatment for their needs,” Victoria Kusiak, MD, deputy director of the Office of Drug Evaluation III in the FDA’s Center for Drug Evaluation and Research, stated in a news release. Clinical trials have been conducted to test the effectiveness of the drug and how safe it is to consume it. In the clinical trials, some men were reported to experience the efficacy of the drug in less than 20 minutes while others had to wait for up to 6 hours to get their erections. 77% of the men who were suffering from general erectile dysfunction in the clinical trials were able to get an erection. And of the men who were suffering from diabetes-related erectile dysfunction at least 63% of the men got to experience an improved erection. The primary and most common downside effects of Avanafil include pain in the back, a stuffy nose, flushing, and headache. It is very rare to hear cases of a prolonged erection, lasting to four or more hours, as a result of Avanafil. But in the case where this happens, it is essential to seek medical attention as soon as possible. Avanafil is not very safe for people who use alcohol. Both Avanafil and alcohol lower blood pressure thus mixing the two of them will lead to a drastic and excessive drop in blood pressure. This will, in turn, cause severe headaches, faintness, and an increased heart rate. Avanafil is a safe drug to use as long as you are within the allowed group of people medically. To ensure total safety do not use the drug if you are allergic to any of its ingredients. Let your doctor or pharmacist know if you have experienced an allergy.
12
info@phcoker.com
Phcoker www.phcoker.com Always follow the instructions given by your doctor or the drug manufacturer. Medical examination will be essential in determining whether the drug is safe for you or not. Don’t just rush to a pharmacy or purchase the Avanafil online without involving your doctor. If you have a health condition or you are undergoing medication of any disease, then the drug might not be safe for you or you will need to take small doses. For those who have adhered to doctor’s advice while using the drug, haven’t complained about any severe side effects. Looking at different customer Avanafil reviews, you can see that the majority of the patients are happy with the results they get after using the drug. The excellent rating of this drug on various platforms is an indicator that it’s delivering and it has helped many people maintain their erections. The few people who have had issues with the drug can be the group that needs to be careful when using the drug which includes men with various medical conditions such as heart disease and strong among other chronic diseases.
10. Storage and disposal safety It is also important that you keep the people around you and your surroundings safe from the drug. Store the medicine in a cool and dry place away from excessive heat and moisture. Ensure the container is always tightly closed and the medication should be kept out of reach for children at all times. Place your medication in locked drawers that are up very high out of the reach and sight of children. If you are done with the medication, and you no longer need it, you should dispose of it in a way that ensures that pets, children, and other people are not going to consume it. Talk to your pharmacist or doctor so you can be informed about the take-back program. The program gives you a chance to take back all medicine that you are not using. This protects humans, animals, and plants from poisoning.
13
info@phcoker.com
Phcoker
www.phcoker.com
11. Avanafil Powder Supplier — Where can I get the Avanafil (330784-47-9)? To get the Avanafil powder, you can visit your local pharmacist and make a purchase. Currently, there are dozens of suppliers selling Avanafil online; you can make an order while you are in the comfort of your home or office. The prices vary from one supplier to the next. However, do your research first to know the right dealer to avoid the risk of purchasing a counterfeit drug. The availability of many Avanafil sellers online makes it hard for many patients to determine the best. There are various factors that you should consider to get the right Avanafil vendor. Read the vendor-customer reviews; this will give you a glimpse of how the seller operates. The delivery timelines, Avanafil price, and reputation should guide you when looking for the best generic ed drugs online dealer. Customer helpdesk should also be quick enough in responding to your questions, and the call lines of a reputable Avanafil online seller should be open throughout. Take time to study various Avanafil powder suppliers before settling on the one you can trust. Your doctor can also help you get the best drug seller around maybe a friend or refer you to a reputable pharmacy. Some clinics also stock the Stendra on their pharmacy, which makes your work easier since the doctor will prescribe and you pick it from there. Before you decide to purchase the drug from any seller, make sure the vendor is certified to operate by relevant government agencies. Avanafil is a drug like any other on the market and should be sold by professionals that understand how it works. The seller should be able to advise you in case of any concerns, and only a medical professional can be in a position to help you. Looking at the accreditation documents is the only most natural way to know if the seller is qualified to sell the drug.
14
info@phcoker.com
Phcoker
www.phcoker.com
12. Avanafil Compared to Tadalafil and Sildenafil Citrate for ED Treatment There are different perspectives that you can use to handle this topic. Many scholars and patients have different opinions when it comes to comparing these threes drugs. The drugs are almost the same since they all treat erectile dysfunction, and they almost work in the same way. Tadalafil, sildenafil and Avanafil, every drug has its fans. There are those who feel one drug is better than the other and others have a different opinion. Basically, human bodies react differently to various drugs, and that’s the reason why there is a debate about which drug is better. All these drugs aim at achieving the same three goals that include;
Help men get an erection Maintain an erection for some time Help men get hard erections
All erectile dysfunction oral such as sildenafil citrate, tadalafil, and Avanafil belong to phosphodiesterase inhibitors type 5. They all work by prolonging the nitric oxide molecule effect on the blood vessels walls in the penis. The nitric oxide presence in the blood vessels increases the blood flow into the penis and maintains the flow for some time resulting in hard, and prolonged erections. The significant difference between the three drugs is the duration and speed of their action. However, patients react differently to the drugs because of genetic differences. No single medicine can be said to be better and effective for every patient.
So how fast are the drugs and how long is their effect? Generally, erectile dysfunction drugs that tend to work faster don’t stay on your body system for long. Which means, you will only feel the effect for some time and you go back to normalcy. Some men get erections faster than others, and this is the factor you should consider when choosing the right drug for you. For instance, if you can plan for sex within the shortest time then go for fast-acting drugs such as Stendra. For the patients who will take time long-acting medicine like tadalafil will be perfect since it stays in the body system for a few days.
a.
Avanafil (330784-47-9)
This drug that sales under the brand name Stendra in the United States of America is among the fastest acting erectile dysfunction medicine. For many patients, the drug starts working in 15 minutes time after taking your dose. Avanafil remains effective for around 6 to 8 hours after that your body returns to normal. That means if you need to have sex again after the 8 hours you will have to take another Avanafil dosage. The standard dose is 100mg, and the maximum is 200mg although it can be reduced or increased by your doctor after examination.
15
info@phcoker.com
Phcoker
b.
www.phcoker.com
Sildenafil (139755-83-2)
Commonly known as Viagra, the drug gives a moderate action compared to Avanafil and Tadalafil. It works in around 30-60 minutes after taking your dose. The effects last for 6 to 12 hours depending on how your body responds to the drug. It’s advisable to take at least one dose a day if you are sure of having sex daily. Alternatively, only take your dose an hour before having sex with your partner. The doses range from 10mg, 20mg, 25mg, 50mg and maximum dose is 100mg.
c.
Tadalafil (171596-29-5)
This drug is also known as Cialis, is a long-acting drug, normally after taking a dose, it will take an hour before you start feeling the effect. However, it stays in your body system for 2-3 days leading to the nickname “weekend drug.” The dosage is between 10mg to 20mg which you should only take once in three days. Alternatively, your doctor can advise you to take the small daily doses of 2.5mg or 5ml. Generally, the drugs are effective in solving the erectile dysfunction in men. Determination of the best drug depends on the patient body reaction and preference. Some people need a short-acting drug, and other want long-acting medicine. Always consult your doctor before choosing the right prescription for your condition. Now that you understand how Avanafil works, you can get it from your nearest pharmacy or online stores but remember to involve your doctor in the decision-making table.
13. 【References】 1. Ryan M Burke, Jeffery D Evans, Avanafil for treatment of erectile dysfunction: review of its potential, Vasc Health Risk Manag. 2012; 8: 517–523.
2. DeRogatis LR, Burnett AL. The epidemiology of sexual dysfunctions. J Sex Med. 2008;5:289–300. 3. Zhao C, Kim S, Yan D, et al. Efficacy and safety of avanafil for treating erectile dysfunction: results of a multicentre, randomized, double-blind, placebo-controlled trial. BJU Int. 2012 Mar 27;
16
info@phcoker.com
