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Phcoker Weight loss powder Lorcaserin hydrochloride hemihydrate buy
Raw Lorcaserin hydrochloride hemihydrate powder (856681-05-5) Specifications Product Name
Raw Lorcaserin hydrochloride hemihydrate powder
Chemical Name
Lorcaserin hydrochloride,(R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate;(R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1h-3-benzazepine hydrochloride hemihydrate
Brand Name
Belviq
Drug Class
5-HT2C receptor inhibitor
CAS Number
856681-05-5
InChIKey
WRZCAWKMTLRWPR-VSODYHHCSA-N
Molecular Formula
C22H32Cl4N2O
Molecular Weight
482.31
Monoisotopic Mass
480.1268745
Melting Point
No data available
Freezing Point
No data available
Biological Half-Life
Lorcaserin has a plasma half life of ~11 hours
Color
White powder
Solubility
Water Solubility 0.0709 mg/mL
Storage Temperature
No data available
Application
Raw Lorcaserin hydrochloride hemihydrate powder used as an anti-obesity drug. It has a role as an appetite depressant and a serotonergic agonist.
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Raw Lorcaserin hydrochloride hemihydrate powder (856681-05-5) Description Lorcaserin hydrochloride hemihydrate powder is a hydrate that is the hemihydrate form of lorcaserin hydrochloride. Used as an anti-obesity drug. It has a role as an appetite depressant and a serotonergic agonist. It contains a lorcaserin hydrochloride. Raw Lorcaserin hydrochloride hemihydrate powder is use to treat obesity associated with high cholesterol, high blood pressure, or type 2 diabetes. The FDA approved the Raw Lorcaserin hydrochloride hemihydrate powder for people who are obese (with a body mass index, or BMI, of 30 or higher) or who are overweight (with a BMI of 27 or above) and also have at least one weight-related health condition such as Type 2 diabetes, high blood pressure or high cholesterol. Raw Lorcaserin hydrochloride hemihydrate powder works by controlling appetite — specifically by activating brain receptors for serotonin, a neurotransmitter that triggers feelings of satiety and satisfaction. Serotonin is also involved in mood; many antidepressant drugs work by preventing the reuptake of serotonin and keeping brain receptors bathed in the chemical. Researchers at Arena say their drug is designed to seek out only the serotonin receptors that affect appetite.
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Lorcaserin hydrochloride hemihydrate powder (856681-05-5) Mechanism of Action Lorcaserin is believed to decrease food consumption and promote satiety by selectively activating 5-HT2C receptors on anorexigenic pro-opiomelanocortin neurons located in the hypothalamus. The exact mechanism of action is not known. Lorcaserin at the recommended daily dose selectively interacts with 5-HT2C receptors as compared to 5-HT2A and 5-HT2B receptors (see Table 5), other 5-HT receptor subtypes, the 5-HT receptor transporter, and 5-HT reuptake sites.
Application of Lorcaserin hydrochloride hemihydrate powder (856681-05-5) 
Appetite depressant: Agent that is used to decrease appetite.

serotonergic agonist: An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
Recommended dosage Lorcaserin hydrochloride hemihydrate powder (856681-05-5) Since the relevant information on the use of Lorcaserin hydrochloride hemihydrate could not be found, the following information is for reference only:
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Lorcaserin HCL powder 846589-98-8 comes in tablet form and is taken typically 1-2 times a day, with or without food. Lorcaserin must be used along with a reduced calorie diet and an exercise plan. The recommended dose of lorcaserin is 10 mg administered by mouth twice a day. Lorcaserin may be taken without regard to meals. Lorcaserin should be discontinued in patients who fail to achieve at least a 5% weight loss by week 12 since these patients are not likely to experience meaningful weight loss with continued treatment.
Benefits of Lorcaserin hydrochloride hemihydrate powder (856681-05-5) Lorcaserin hydrochloride hemihydrate powder is a selective 5-HT2C receptor agonist that is thought to decrease food intake through the central POMC system. Lorcaserin HCL powder benefits:
Lorcaserin hydrochloride hemihydrate powder is used together with diet and exercise to treat obesity.
Lorcaserin hydrochloride hemihydrate powder is sometimes used to treat obesity that may be related to diabetes, high cholesterol, or high blood pressure.
Lorcaserin hydrochloride hemihydrate powder will not treat any underlying health condition (such as heart disease, diabetes, high blood pressure).
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Side effects of Lorcaserin hydrochloride hemihydrate powder (856681-05-5) Lorcaserin hydrochloride hemihydrate powder is used for the treatment of chronic weight management in adults with a body mass index (BMI) of 30 or greater (obese) as an addition to a reduced-calorie diet and exercise. It is also approved for use by adults with a BMI of 27 or greater (overweight) and who have at least one weight-related condition such as high blood pressure (hypertension), or high cholesterol (dyslipidemia). However, it also may have some side effects. As below: The most common side effects:
-Headache,
-Dizziness,
-Fatigue,
-Nausea,
-Dry mouth,
-Constipation, and
-Hypoglycemia (low blood sugar).
Other less common but serious side effects associated with lorcaserin include:
-Heart valve problems,
-Changes in attention or memory,
-Mental problems, 5
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-Depression or thoughts of suicide,
-Painful erections,
-Slow heartbeat,
-A drop in blood cell count, and
-An increase in the hormone, prolactin.
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