Phcoker
Xuchang shangke Chemical Co., Ltd
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Raw Tianeptine powder (66981-73-5) Specifications Product Name
Raw Tianeptine powder
Chemical Name
Raw Tianeptine powder; 66981-73-5; 72797-41-2; Raw Tianeptine powder Acid; Raw Tianeptine powder
Brand Name
Yocon
Drug Class
depressive episodes
CAS Number
66981-73-5
InChIKey
JICJBGPOMZQUBB-UHFFFAOYSA-N
Molecular Formula
C21H25ClN2O4S
Molecular Weight
436.951 g/mol
Monoisotopic Mass
436.122 g/mol
Melting Point
148
Boiling Point
609.2
Biological Half-Life
No date available
Color
White to off-white powder
Solubility
No date available
Storage Temperature
Refrigerator
Application
It is a drug used for treating major depressive episodes (mild, moderate, or severe).
Tianeptine overview Raw Tianeptine powder is an antidepressant agent with a novel neurochemical profile.Raw Tianeptine powder does not appear to be associated with adverse cognitive, psychomotor, sleep, cardiovascular or bodyweight effects and has a low propensity for abuse. Raw Tianeptine powder has a comparatively favourable pharmacokinetic profile. It is not subject to first-pass hepatic 1
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Phcoker
Xuchang shangke Chemical Co., Ltd
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metabolism, has high bioavailability and limited distribution, and is rapidly eliminated. While this offers advantages for Raw Tianeptine powder over the tricyclic antidepressant agents in terms of dose titration, treatment changes and potential drug interactions, its rapid elimination makes adherence to dosage schedules more important. Raw Tianeptine powder differs from most antidepressants in that it is not primarily metabolised by the hepatic cytochrome P450 system, indicating less likelihood of drug-drug interactions; this is of particular interest for elderly patients.
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Phcoker
Xuchang shangke Chemical Co., Ltd
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Raw Tianeptine powder (66981-73-5) Description Tianeptine powder is a drug primarily used to improve the symptoms of major depressive disorder (MDD). It has also been used to help irritable bowel syndrome and asthma. Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants. Tianeptine was discovered and patented by the French society of Medical Research in the 1960s. It’s brand names include Stablon, Coaxil. Tatinol, Tianeurax, and Salymbra. Tianeptine powder does not appear to be associated with adverse cognitive, psychomotor, sleep, cardiovascular or bodyweight effects and has a low propensity for abuse. Raw Tianeptine powder has a comparatively favourable pharmacokinetic profile. It is not subject to first-pass hepatic metabolism, has high bioavailability and limited distribution, and is rapidly eliminated. While this offers advantages for Raw Tianeptine powder over the tricyclic antidepressant agents in terms of dose titration, treatment changes and potential drug interactions, its rapid elimination makes adherence to dosage schedules more important. Raw Tianeptine powder differs from most antidepressants in that it is not primarily metabolised by the hepatic cytochrome P450 system, indicating less likelihood of drug-drug interactions; this is of particular interest for elderly patients.
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Phcoker
Xuchang shangke Chemical Co., Ltd
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Recently, Tianeptine is available in European, Asian, and South American countries. It is banned in the United Kingdom and is not medically prescribed by doctors in the United States.
Tianeptine powder (66981-73-5) Mechanism of Action Recent studies suggest that tianeptine acts as a full agonist at the mu-type opioid receptor (MOR). The mu opioid receptors are currently being studied as effective targets for antidepressant therapies. It is believed that the clinical effects of tianeptine are owed to its modulation of these receptors. In addition to its actions on the opioid receptor, previous studies have owed its action to its effect on the serotonin receptor dopamine (D2/3) receptors and glutamate receptors. Tianeptine powder is a unique antidepressant and anxiolytic medication that stimulates the uptake of serotonin (5-hydroxytryptamine; 5-HT), and 5-hydroxyindoleacetic acid (5-HIAA) in brain tissue. Although the monoaminergic neurotransmitters serotonin (5-HT), noradrenaline (NA) and dopamine (DA) are proven to be related to the occurrence of depressive disorders, it is now recognized that monoamine deficits are not sufficient to explain the mechanism of action of antidepressant medications. 4
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Phcoker
Xuchang shangke Chemical Co., Ltd
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Application of Tianeptine powder (66981-73-5) ▪ Tianeptine improve the symptoms of major depressive disorder (MDD) ▪ Tianeptine help irritable bowel syndrome and asthma ▪ Tianeptine improve mood and soothes anxiety. ▪ Tianeptine increases how much serotonin the brain absorbs ▪ Tianeptine enhance motivation, focus and cognitive, suppress anxiety, rejuvenation and reduce cognitive fatigue.
Recommended Tianeptine powder (66981-73-5) Dosage Tianeptine powder is generally prescribed at a dose of 12.5 mg and taken three times per day. Unlike other TCAs and selective serotonin reuptake inhibitors (SSRIs), tianeptine doses do not need to be increased slowly and a taper when the medication is discontinued is not required.
Side effects of Tianeptine powder (66981-73-5) The side effects of tianeptine powder are surprisingly limited. Compared to other TCAs and even the SSRI class of antidepressants, tianeptine powder is almost free of side effects. Despite its mild side effect profile, it is important
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Xuchang shangke Chemical Co., Ltd
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not to mix tianeptine with monoamine oxidase inhibitors or other antidepressants as the combinations could be life threatening. Tianeptine should also not be mixed with anesthetics and its use should cease 24-48 prior to surgical intervention requiring anesthetics or hypnotics. Here are a few of the more common side effects associated with tianeptine. ▲ Constipation ▲ Diarrhea ▲ Indigestion ▲ Vomiting ▲ Dry mouth ▲ Fatigue ▲ Insomnia ▲ Changes in appetite ▲ Dizziness ▲ Respiratory depression ▲ Sleepiness ▲ Blurred vision ▲ Decreased sex drive 6
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Xuchang shangke Chemical Co., Ltd
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▲ Headache ▲ Itching
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