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Xuchang shangke Chemical Co., Ltd
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Raw Alpha GPC (Choline Alfoscerate) powder (28319-77-9) Specifications Product Name
Raw Alpha GPC powder
Chemical Name
Choline Alfoscerate; Alpha GPC; L-Alpha glycerylphosphorylcholine; Choline glycerophosphate
Brand Name
No date available
Drug Class
parasympathomimetic acetylcholine
CAS Number
28319-77-9
InChIKey
SUHOQUVVVLNYQR-QMMMGPOBSA-N
Molecular Formula
C8H20NO6P
Molecular Weight
257.223 g/mol
Monoisotopic Mass
257.103 g/mol
Melting Point
142.5 °C
Freezing Point
No date available
Biological Half-Life
The Alpha GPC half-life is around 4-6 hours but is said to peak within 1-2 hours of ingestion
Color
Solid powder
Solubility
Soluble in DMSO
Storage Temperature
0 – 4°C for short term (days to weeks), or -20 °C for long term (months).
Application
Choline Alfoscerate is used in the treatment of Alzheimer’s Disease and other dementias.
Raw Alpha GPC (Choline Alfoscerate) powder (28319-77-9) Description Alpha GPC is the common name for L-Alpha glycerylphosphorylcholine, a cholinergic nootropic that occurs naturally but can also be taken as a supplement. Alpha GPC powder is best known for quickly and reliably delivering choline to the brain for the creation of the cognition-boosting neurotransmitter acetylcholine. 1
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Phcoker
Xuchang shangke Chemical Co., Ltd
www.phcoker.com
It has powerful benefits for both brain and body and may enhance the full range of cognitive functions, promote cellular health, and help maintain essential neurochemical balance in the brain.
Alpha-GPC rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of acetylcholine. It is a non-prescription drug in most countries. The FDA determined that intake of no more than 196.2 mg/person/day is considered GRAS. In some European countries, it is regulated as a prescription drug and used for the treatment of Alzheimer’s disease. Raw Alpha GPC powder (28319-77-9) Mechanism of Action?
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Phcoker
Xuchang shangke Chemical Co., Ltd
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Alpha-GPC supports the whole nervous system by boosting acetylcholine and cholinergic activity. It may also raise the levels of other brain-protective messengers such as: GABA Dopamine Serotonin Inositol phosphate Plus, as mentioned, it might boost growth hormone levels as well. Benefits of Alpha GPC (Choline Alfoscerate) powder (28319-77-9) Improved Memory and Enhanced Cognition Neuroprotectant Improves Stroke Recovery Boosts Athletic Performance,Increased Strength and Rapid Post-Workout Recovery May Improve Eyesight May Protect Against Radiation Recommended Alpha GPC (Choline Alfoscerate) (28319-77-9) Dosage
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Phcoker
Xuchang shangke Chemical Co., Ltd
www.phcoker.com
Alpha GPC is about 40% choline by weight. So 1,000 mg of Alpha GPC powder provides approximately 400 mg of choline. Alpha GPC suggested dosage for cognitive benefits is 250–1,200 mg per day. Here’s a breakdown of the dosing regimens: Alzheimer’s disease and dementia: 400 mg, 3X daily for 6 – 12 months. Stroke recovery: 1,000 mg daily for 1 month (as injections). 400 mg orally, 3X daily for 5 months afterward Athletic performance: 250 mg daily for 1 week 600 mg daily for 1 – 6 days. Eyesight: 400 mg, 2X daily for 2 months. According to anecdotal evidence, the dose for nootropic effects ranges from 400 to 1,200 mg/day. You might want to start on the lower end and track your response. Side effects of Alpha GPC powder (28319-77-9) Alpha-GPC powder was safe in all clinical trials. In a fraction of patients, it caused mild side effects such as: Heartburn Nausea 4
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Phcoker
Xuchang shangke Chemical Co., Ltd
www.phcoker.com
Irritability Headache In safety studies on dogs and rats, megadoses (up to 3,000 mg/kg) only slightly reduced the animals’ activity. Researchers concluded that long-term (26 weeks) alpha-GCP consumption of 150 mg/kg (over 10 g daily for adult men) bears no health risks. Due to the lack of safety data, children and pregnant women may want to avoid alpha-GPC.
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