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Cayman Pharma s.r.o., a Subsidiary of US-based Cayman Chemicals Company, Inc.
For further details, please visit www.caymanpharma.com. Please feel free to contact us at caymanpharma@caymanpharma. com. For the management of glaucoma, our prostaglandin derivatives Latanoprost, Travoprost, Bimatoprost, and Tafluprost, all have validated GMP routes and regulatory approvals needed for export worldwide. Our ophthalmology APIs are the front-line medications for the treatment of glaucoma, | 12
a condition resulting in blindness due to the death of retinal ganglion cells. These prostaglandins act by lowering intraocular pressure, a major risk factor for glaucoma that represents the second most common cause of blindness. Management of pulmonary hypertension is facilitated by our vascular API Epoprostenol. Our historically oldest veterinaty API, Cloprostenol, is used for the synchronisation of mating season for large animals. Majority of produced material in the form of API leaves the Czech Republic and is exported to 57 countries around the world to local manufacturers of final formulations. Even though Cayman Pharma is a part of the Cayman global concept, the atmosphere inside of the company is retained on a very close personal level in a family-like
environment. Majority of the employees stay with the company for most, if not all, of their professional career and actively participate in the development of prostaglandin know-how. Prostaglandins are hormones like compounds that can be found in practically all organs of the body and have many different physiological functions. Chemically, they are derived from arachidonic acid and through the change of chemical groups and substituents, they gain specific pharmacological properties. Production of prostaglandin APIs is one of most technologically challenging processes in the pharmaceutical industry. From starting material to the final API, pro-
duction processes take up to 6 months due to the complexity of prostaglandin chemistry. Although the quantities sold are indicated in grams, the material produced has great added value due to the multistep manufacturing process.
Photo: Cayman Pharma s.r.o. archives
Cayman Pharma s.r.o., a subsidiary of US-based Cayman Chemicals Company, Inc. (Ann Arbor, Michigan), is one of the world’s most reliable and versatile sources for prostaglandin active pharmaceutical ingredients (APIs). Located in Neratovice, near Prague, Cayman Pharma has over 40 years of commercial prostaglandin manufacturing experience, is ISO certified, and has an excellent track record with customers and regulatory authorities worldwide, including the FDA and European regulatory authorities. With 140 employees, Cayman Pharma is a dynamic employer with emphasis on employee career development and GMP compliance.
