Women in Autism Spectrum Disorders

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GENDER IN AUTISM María Merino

¿Porqué es necesario? ¿Qué sabemos?

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Schematic of the pipeline for creating the SC.

Madhura Ingalhalikar et al. PNAS 2014;111:823-828

Š2014 by National Academy of Sciences

Connection-wise analysis.

Madhura Ingalhalikar et al. PNAS 2014;111:823-828

Š2014 by National Academy of Sciences

Representative regions of the brain that have a higher PC at a significance level of P < 0.001.

Madhura Ingalhalikar et al. PNAS 2014;111:823-828

Š2014 by National Academy of Sciences

Brain structures showing significant interaction and main effects in the 2 x 2 factorial design VBM. (A) Clusters were overlaid on the grey matter segment of the study-specific template.

Meng-Chuan Lai et al. Brain 2013;brain.awt216 Š The Author 2013. Published by Oxford University Press on behalf of the Guarantors of Brain.

Testing brain-level predictions of the EMB theory of autism.

Meng-Chuan Lai et al. Brain 2013;brain.awt216 Š The Author 2013. Published by Oxford University Press on behalf of the Guarantors of Brain.

White matter overlapping regions in females coincide with clusters showing a significant sex × diagnosis interaction in the 2 × 2 factorial design.

Meng-Chuan Lai et al. Brain 2013;brain.awt216 © The Author 2013. Published by Oxford University Press on behalf of the Guarantors of Brain.

Overlapping region and 2D:4D ratio.

Meng-Chuan Lai et al. Brain 2013;brain.awt216 Š The Author 2013. Published by Oxford University Press on behalf of the Guarantors of Brain.

A Genome-wide Association Study of Autism Using the Simons Simplex Collection: Does Reducing Phenotypic Heterogeneity in Autism Increase Genetic Homogeneity?

Pauline Chaste, Lambertus Klei, Stephan J. Sanders, Vanessa Hus, Michael T. Murtha, Jennifer K. Lowe, A. Jeremy Willsey, Daniel Moreno-De-Luca, Timothy W. Yu, Eric Fombonne, Daniel Geschwind, Dorothy E. Grice, David H. Ledbetter, Shrikant M. Mane, Donna M. Martin, Eric M. Morrow, Christopher A. Walsh, James S. Sutcliffe, Christa Lese Martin, Arthur L. Beaudet, Catherine Lord, Matthew W. State, Edwin H. Cook, and Bernie Devlin Biological Psychiatry (2015) 77: 775

Increase in risk to siblings of female probands above the 90th percentile.

Elise B. Robinson et al. PNAS 2013;110:5258-5262

Š2013 by National Academy of Sciences

Fig. 1. The genetic mechanisms that underlie attention and impulsivity in both the healthy and the neuropsychiatric population. The expression of sex linked genes including SRY, STS and MAOA are sexually dimorphic (SRY is only expressed in males and STS has a ...

Simon Trent, William Davies The influence of sex-linked genetic mechanisms on attention and impulsivity Biological Psychology, Volume 89, Issue 1, 2012, 1â&#x20AC;&#x201C;13

http://dx.doi.org/10.1016/j.biopsycho.2011.09.011

What to do?

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Needs and Facts in women with ASD

LEARNING MODULE (English, Potuguese, Lithuan, Spanish)

HISPANIC RESEARCH WOMEN AND ASD, AETAPI

* Awareness

*SOCIAL NETWORKS

* autismoburgos@autuismoburgos.org psicologia@autismoburgos.org