INTERPHEX JAPAN 2014

IPJ14_BRC_E_H1_H4_ABE

Pharmaceutical industrial professionals all gathered under one roof.

VIP PARTY

Conference

Our attendees appreciated this event as the only one venue for them to meet with the worldwide pharmaceutical industry leaders.

Our exhibitors can utilize this party to gain a pathway to Japan and Asian markets.

Along the exhibition, professional presentations will be held throughout the 3-day show period. INTERPHEX JAPAN allows you to grab on overview of the entire pharmaceutical technology trend in Japan and Asia. In previous show of 2013, a total of 19 sessions attracted 2,956 attendees and brought them also to the exhibition halls in 2013.

-For your networking

-For your advance

Japan’s Largest International Trade Show for Pharmaceutical R&D and Manufacturing

2013 Keynote Session

The Japanese Pharmaceutical Industry -Key for Rapid Growth

President & Representative Director, Otsuka Pharmaceutical Co., Ltd.

Representative Director and President, MSD K.K.

Director, Equity Research, Equities, Credit Suisse Securities (JAPAN) Ltd.

Taro Iwamoto

Tony Alvarez

Fumiyoshi Sakai (Honorifics omitted)

2014

27th INT'L PHARMACEUTICAL R&D AND MANUFACTURING EXPO/CONFERENCE Dates: July 2 (Wed) - 4 (Fri) , 2014 Venue: Tokyo Big Sight, Japan Organised by: Reed Exhibitions Japan Ltd.

INTERPHEX JAPAN Show Management Attn: Fumiko Ichikawa(Ms.), Megumi Yanai (Ms.) Reed Exhibitions Japan Ltd. 18F Shinjuku-Nomura Bldg., 1-26-2 Nishishinjuku, Shinjuku-ku, Tokyo 163-0570, Japan Web: www.interphex.jp/en/ TEL: +81-3-3349-8518 FAX: +81-3-3349-8530 E-mail: interphex@reedexpo.co.jp A division of Reed Business Registered in England, Number 678540

Concurrent Show: in-PHARMA JAPAN 2014 — 8th INT'L PHARMACEUTICAL INGREDIENTS EXPO & CONFERENCE

www.interphex.jp/en/

IPJ_J14_BRC_E_P1_P2_matsumoto

L argest-scale ever! Huge success with the record number of 970 exhibitors. *

Great number of 32,762 pharmaceutical visitors all gathered under one roof. *

The Solemn Declaration of No Inflated Numbers

We consistently count visitor registration numbers clearly and stringently and, without deception, continue to release the real numbers. Please refer to the following URL for details on the counting method.

www.interphex.jp/en/doc/TAC/

* including the concurrent show

IPJ_J14_BRC_E_P1_P2_matsumoto

L argest-scale ever! Huge success with the record number of 970 exhibitors. *

Great number of 32,762 pharmaceutical visitors all gathered under one roof. *

The Solemn Declaration of No Inflated Numbers

We consistently count visitor registration numbers clearly and stringently and, without deception, continue to release the real numbers. Please refer to the following URL for details on the counting method.

www.interphex.jp/en/doc/TAC/

* including the concurrent show

IPJ14_BRC_E_P3_P4_ABE

I NTERPHEX JAPAN 2014 will be largest ever again.

INTERPHEX JAPAN will be ...

1,100

FLOOR PLAN (preliminary)

*

exhibitors from worldwide

Exhibit Profile

35,000

*

professionals in the industry

Covering the whole process of Pharmaceutical R&D and Manufacturing Plant Engineering Zone Biopharma Zone

Materials Process Zone

Supplies & Transfer Zone

Sterilizing Equipment & Clean Room Zone Water Production/ Control Zone

East Hall 2 Entrance/Exit East Hall 6 Entrance/Exit

Meeting at

INTERPHEX JAPAN 2014

INTERPHEX JAPAN

Materials Process ■ Sterilizing Equipment & Clean Room ■ Process Inspection/Testing Equipment ■ Laboratory Measurement/Analysis Equipment ■ Water Production/Control ■ Supplies & Transfer ■ Biopharma ■ Plant Engineering ■ IT Solutions ■ Logistics ■ Contract Services etc.

■

(* expected, including the concurrent show)

■

Packaging Machines/Materials, Containers

Visitor Profile Pharmaceutical/Cosmetics/Detergent/Food Manufacturers: Manufacturing Technology ■ Product Quality Control R&D ■ Factory Control ■ Purchasing/Facilities ■ Engineering ■ Production ■ Marketing & Sales ■ ICT ■ IT etc.

■

◆

◆

Active Negotiations Technical Consultations

■

Related Industry Professionals: ◆

Delivery Date/ Price Arrangement

■

Producers (Cosmetics, Intermediates, Custom Syntheses, Generics, OTC)

Original Molecule Designers Research Institutes ■ Regulatory Institutes ■ ■

PHARMA PACK 2014

IT Solutions Zone

Laboratory Measurement/ Analysis Equipment Zone East Hall 3 Entrance/Exit

Most effective venue to develop business in Japan & Asia

etc.

2013 Exhibitor Comments (excerpt)

etc.

2013 Visitor Comments (excerpt)

East Hall 1 Entrance/Exit East Hall 5 Entrance/Exit

Process Inspection/ Testing Equipment Zone

PHARMA PACK 2014 Logistics Zone

East Hall 4 Entrance/Exit

M TECHNIQUE CO., LTD. We had 23 concrete business discussions about emulsification equipment. We already made a deal of USD 3 million.

in-PHARMA JAPAN 2014

OHKI INDUSTRY CO., LTD. Even as a first-time exhibitor at INTERPHEX JAPAN, we could receive great response from visitors by introducing our polishing technique. We are now under the business negotiation with more than 30 companies. Our sales amount will reach over USD 30 million.

DAIICHI SANKYO PROPHARMA CO., LTD. We met mainly with exhibitors on site with whom we had made appointments beforehand. We plan to purchase drug formulation/inspection equipment for USD 1 million.

— 8th INT'L PHARMACEUTICAL INGREDIENTS EXPO & CONFERENCE

Contract Services Zone

KYOWA DENKI CO., LTD. We exhibit INTERPHEX JAPAN every year as the best place to meet new potential customers in pharmaceutical industry and this year sales amount will be USD 500,000 for packaging machine.

SOKEN TECNIX CO., LTD. We exhibited agitator and 250 professionals visited our booth.

5 deals have been successfully closed and our sales amount is estimated to reach USD 300,000.

TAKEDA PHARMACEUTICAL CO., LTD. We made comparative review of single-use products specialised for biotechnology-based medicines with a couple of exhibitors.

Ordering amount will be USD 300,000.

IPJ14_BRC_E_P3_P4_ABE

I NTERPHEX JAPAN 2014 will be largest ever again.

INTERPHEX JAPAN will be ...

1,100

FLOOR PLAN (preliminary)

*

exhibitors from worldwide

Exhibit Profile

35,000

*

professionals in the industry

Covering the whole process of Pharmaceutical R&D and Manufacturing Plant Engineering Zone Biopharma Zone

Materials Process Zone

Supplies & Transfer Zone

Sterilizing Equipment & Clean Room Zone Water Production/ Control Zone

East Hall 2 Entrance/Exit East Hall 6 Entrance/Exit

Meeting at

INTERPHEX JAPAN 2014

INTERPHEX JAPAN

Materials Process ■ Sterilizing Equipment & Clean Room ■ Process Inspection/Testing Equipment ■ Laboratory Measurement/Analysis Equipment ■ Water Production/Control ■ Supplies & Transfer ■ Biopharma ■ Plant Engineering ■ IT Solutions ■ Logistics ■ Contract Services etc.

■

(* expected, including the concurrent show)

■

Packaging Machines/Materials, Containers

Visitor Profile Pharmaceutical/Cosmetics/Detergent/Food Manufacturers: Manufacturing Technology ■ Product Quality Control R&D ■ Factory Control ■ Purchasing/Facilities ■ Engineering ■ Production ■ Marketing & Sales ■ ICT ■ IT etc.

■

◆

◆

Active Negotiations Technical Consultations

■

Related Industry Professionals: ◆

Delivery Date/ Price Arrangement

■

Producers (Cosmetics, Intermediates, Custom Syntheses, Generics, OTC)

Original Molecule Designers Research Institutes ■ Regulatory Institutes ■ ■

PHARMA PACK 2014

IT Solutions Zone

Laboratory Measurement/ Analysis Equipment Zone East Hall 3 Entrance/Exit

Most effective venue to develop business in Japan & Asia

etc.

2013 Exhibitor Comments (excerpt)

etc.

2013 Visitor Comments (excerpt)

East Hall 1 Entrance/Exit East Hall 5 Entrance/Exit

Process Inspection/ Testing Equipment Zone

PHARMA PACK 2014 Logistics Zone

East Hall 4 Entrance/Exit

M TECHNIQUE CO., LTD. We had 23 concrete business discussions about emulsification equipment. We already made a deal of USD 3 million.

in-PHARMA JAPAN 2014

OHKI INDUSTRY CO., LTD. Even as a first-time exhibitor at INTERPHEX JAPAN, we could receive great response from visitors by introducing our polishing technique. We are now under the business negotiation with more than 30 companies. Our sales amount will reach over USD 30 million.

DAIICHI SANKYO PROPHARMA CO., LTD. We met mainly with exhibitors on site with whom we had made appointments beforehand. We plan to purchase drug formulation/inspection equipment for USD 1 million.

— 8th INT'L PHARMACEUTICAL INGREDIENTS EXPO & CONFERENCE

Contract Services Zone

KYOWA DENKI CO., LTD. We exhibit INTERPHEX JAPAN every year as the best place to meet new potential customers in pharmaceutical industry and this year sales amount will be USD 500,000 for packaging machine.

SOKEN TECNIX CO., LTD. We exhibited agitator and 250 professionals visited our booth.

5 deals have been successfully closed and our sales amount is estimated to reach USD 300,000.

TAKEDA PHARMACEUTICAL CO., LTD. We made comparative review of single-use products specialised for biotechnology-based medicines with a couple of exhibitors.

Ordering amount will be USD 300,000.

IPJ14_BRC_E_P5_P6_ABE

The best place to meet high-quality visitors from Japan & Asia.

Free Advertising Opportunities for Exhibitors

INTERPHEX JAPAN attracts significant number of professionals from pharmaceutical manufacturing companies and most of them are decision makers for new product purchasing.

You can meet all key industrial professionals during the show.

9.2 %

Presidents, Chairmen, Executive Officers

*1

35,000 professionals to visit in 2014

15.6 % Directors, Senior Officials

36.1% Others

decision makers!

2. Direct E-mailing

1. Direct Mailing A large number of invitation tickets will be sent out to industry executives and professionals in Japan/Asia and all over the world. These invitation tickets will have your company information listed, enhancing you to gain further recognition among industry professionals.

“INTERPHEX JAPAN Newsletters” will be sent to a large number of industry professionals regularly. These include information on exhibitors and their technologies as well as conferences, business matching events and various other information. <SAMPLE>

4. Press Release Service

3. Online Advertising

(32,762*2 professionals visited in 2013)

% 63.9of total visitors were

Extensive support services maximise your results.

19.1 % Managers

20.0%

Assistant Managers, Section Heads

Your company name and technology/product details will be listed on the “e-Guidebook”, which has high access from industry professionals worldwide. The “e-Guidebook” is also linked to your company website, therefore also generating more traffic to your website and your booth. The “e-Guidebook” opens 2 months prior to the event for 1 year, maximising your pre-show/post-show publicity.

<IMAGE>

To maximise media coverage, Show Management will prepare “Highlight of Exhibits”- an online media release covering information on exhibitors, sent directly to major press. This will encourage press members to have interviews on your technologies/products leading to further pre-show/post-show publicity.

The figures above are calculated from visitors in 2013 and include concurrent show. *1 expected, including the concurrent show *2 including the concurrent show

Special Support Services for Exhibitors

INTERPHEX JAPAN 2013 visitors (excerpt)

1. Special Discount for Hotel Reservation

Major Pharmaceutical Companies DAIICHI SANKYO DAINIPPON SUMITOMO PHARMA ■ EISAI ■ ELI LILLY ■ GLAXOSMITHKLINE ■ HISAMITSU PHARMACEUTICAL

JANSEN PHARMACEUTICAL KISSEI PHARMACEUTICAL ■ KYOWA HAKKO KIRIN ■ MITSUBISHI TANABE PHARMA ■ MOCHIDA PHARMACEUTICAL ■ MSD

NIPPIN SHINYAKU NOVARTIS PHARMA ■ NOVO NORDISK ■ ONO PHARMACEUTICAL ■ OTSUKA PHARMACEUTICAL ■ PFIZER

SANTEN PHARMACEUTICAL SHIONOGI ■ TAISHO PHARMACEUTICAL ■ TAKEDA PHARMACEUTICAL ■ TEIJIN PHARMA ■ TSUMURA

■

■

■

■

■

■

■

■

■

…

ABBOTT AJINOMOTO PHARMACEUTICAL ■ ASAHI KASEI PHARMA ■ ASTELLAS PHARMA ■ BOEHRINGER INGELHEIM ■ CHUGAI PHARMACEUTICAL ■

Major Importers EUROTECHNO GADELIUS ■ HIGUCHI ■ JAPAN MACHINERY

KOWA LEYBOLD ■ MITSUBISHI ■ MITSUI

MUTUAL NAGASE ■ SUMITOMO ■ WINCKLER

■

■

■

■

■

■

■

…

CBC DAIICHI JITSUGYO ■ DKSH JAPAN ■ ESTECH ■

Special discount rates are offered to exhibitors at standard international hotels, convenient, and located close to the exhibition site.

2. Translation/Interpreter Services For exhibitors to prepare Japanese leaflets, signboards, etc. translation service is available at a reasonable price.

If you wish to hire an interpreter for smooth communication with Japanese visitors, you can choose one among wide options, from basic- to advanced- levels.

3. Other Various Support Services Booth construction, shipping services are also available. Please refer to the “Exhibitor Manual” on the Exhibitors Website.

<IMAGE>

<IMAGE>

IPJ14_BRC_E_P5_P6_ABE

The best place to meet high-quality visitors from Japan & Asia.

Free Advertising Opportunities for Exhibitors

INTERPHEX JAPAN attracts significant number of professionals from pharmaceutical manufacturing companies and most of them are decision makers for new product purchasing.

You can meet all key industrial professionals during the show.

9.2 %

Presidents, Chairmen, Executive Officers

*1

35,000 professionals to visit in 2014

15.6 % Directors, Senior Officials

36.1% Others

decision makers!

2. Direct E-mailing

1. Direct Mailing A large number of invitation tickets will be sent out to industry executives and professionals in Japan/Asia and all over the world. These invitation tickets will have your company information listed, enhancing you to gain further recognition among industry professionals.

“INTERPHEX JAPAN Newsletters” will be sent to a large number of industry professionals regularly. These include information on exhibitors and their technologies as well as conferences, business matching events and various other information. <SAMPLE>

4. Press Release Service

3. Online Advertising

(32,762*2 professionals visited in 2013)

% 63.9of total visitors were

Extensive support services maximise your results.

19.1 % Managers

20.0%

Assistant Managers, Section Heads

Your company name and technology/product details will be listed on the “e-Guidebook”, which has high access from industry professionals worldwide. The “e-Guidebook” is also linked to your company website, therefore also generating more traffic to your website and your booth. The “e-Guidebook” opens 2 months prior to the event for 1 year, maximising your pre-show/post-show publicity.

<IMAGE>

To maximise media coverage, Show Management will prepare “Highlight of Exhibits”- an online media release covering information on exhibitors, sent directly to major press. This will encourage press members to have interviews on your technologies/products leading to further pre-show/post-show publicity.

The figures above are calculated from visitors in 2013 and include concurrent show. *1 expected, including the concurrent show *2 including the concurrent show

Special Support Services for Exhibitors

INTERPHEX JAPAN 2013 visitors (excerpt)

1. Special Discount for Hotel Reservation

Major Pharmaceutical Companies DAIICHI SANKYO DAINIPPON SUMITOMO PHARMA ■ EISAI ■ ELI LILLY ■ GLAXOSMITHKLINE ■ HISAMITSU PHARMACEUTICAL

JANSEN PHARMACEUTICAL KISSEI PHARMACEUTICAL ■ KYOWA HAKKO KIRIN ■ MITSUBISHI TANABE PHARMA ■ MOCHIDA PHARMACEUTICAL ■ MSD

NIPPIN SHINYAKU NOVARTIS PHARMA ■ NOVO NORDISK ■ ONO PHARMACEUTICAL ■ OTSUKA PHARMACEUTICAL ■ PFIZER

SANTEN PHARMACEUTICAL SHIONOGI ■ TAISHO PHARMACEUTICAL ■ TAKEDA PHARMACEUTICAL ■ TEIJIN PHARMA ■ TSUMURA

■

■

■

■

■

■

■

■

■

…

ABBOTT AJINOMOTO PHARMACEUTICAL ■ ASAHI KASEI PHARMA ■ ASTELLAS PHARMA ■ BOEHRINGER INGELHEIM ■ CHUGAI PHARMACEUTICAL ■

Major Importers EUROTECHNO GADELIUS ■ HIGUCHI ■ JAPAN MACHINERY

KOWA LEYBOLD ■ MITSUBISHI ■ MITSUI

MUTUAL NAGASE ■ SUMITOMO ■ WINCKLER

■

■

■

■

■

■

■

…

CBC DAIICHI JITSUGYO ■ DKSH JAPAN ■ ESTECH ■

Special discount rates are offered to exhibitors at standard international hotels, convenient, and located close to the exhibition site.

2. Translation/Interpreter Services For exhibitors to prepare Japanese leaflets, signboards, etc. translation service is available at a reasonable price.

If you wish to hire an interpreter for smooth communication with Japanese visitors, you can choose one among wide options, from basic- to advanced- levels.

3. Other Various Support Services Booth construction, shipping services are also available. Please refer to the “Exhibitor Manual” on the Exhibitors Website.

<IMAGE>

<IMAGE>

IPJ14_BRC_E_H1_H4_ABE

Pharmaceutical industrial professionals all gathered under one roof.

VIP PARTY

Conference

Our attendees appreciated this event as the only one venue for them to meet with the worldwide pharmaceutical industry leaders.

Our exhibitors can utilize this party to gain a pathway to Japan and Asian markets.

Along the exhibition, professional presentations will be held throughout the 3-day show period. INTERPHEX JAPAN allows you to grab on overview of the entire pharmaceutical technology trend in Japan and Asia. In previous show of 2013, a total of 19 sessions attracted 2,956 attendees and brought them also to the exhibition halls in 2013.

-For your networking

-For your advance

Japan’s Largest International Trade Show for Pharmaceutical R&D and Manufacturing

2013 Keynote Session

The Japanese Pharmaceutical Industry -Key for Rapid Growth

President & Representative Director, Otsuka Pharmaceutical Co., Ltd.

Representative Director and President, MSD K.K.

Director, Equity Research, Equities, Credit Suisse Securities (JAPAN) Ltd.

Taro Iwamoto

Tony Alvarez

Fumiyoshi Sakai (Honorifics omitted)

2014

27th INT'L PHARMACEUTICAL R&D AND MANUFACTURING EXPO/CONFERENCE Dates: July 2 (Wed) - 4 (Fri) , 2014 Venue: Tokyo Big Sight, Japan Organised by: Reed Exhibitions Japan Ltd.

INTERPHEX JAPAN Show Management Attn: Fumiko Ichikawa(Ms.), Megumi Yanai (Ms.) Reed Exhibitions Japan Ltd. 18F Shinjuku-Nomura Bldg., 1-26-2 Nishishinjuku, Shinjuku-ku, Tokyo 163-0570, Japan Web: www.interphex.jp/en/ TEL: +81-3-3349-8518 FAX: +81-3-3349-8530 E-mail: interphex@reedexpo.co.jp A division of Reed Business Registered in England, Number 678540

Concurrent Show: in-PHARMA JAPAN 2014 — 8th INT'L PHARMACEUTICAL INGREDIENTS EXPO & CONFERENCE

www.interphex.jp/en/