An Education Above
TM
Laurel Leaf Fall 2013
Hope for Future of Mental Illness Treatment
Zink’s Breakthrough Research Provides
I
n early November, as this year’s Sarah Crane Cohen Visiting Scholar in the Humanities, Dr. Caroline F. Zink, 1995, returned to the Sinex Theater podium for the first time since her senior speech to share her latest neurological research. While at RPCS, Cary—as we affectionately call her—was a Semiquaver and received the Sidney Silber Award for her love of learning, intellectual curiosity and achievement in the fields of math and science as a senior at Class Day. After graduating from RPCS, Dr. Zink received a B.S. and Ph.D. in Neuroscience from Emory University. She performed her post-doctoral training in the Unit for Systems Neuroscience in Psychiatry at the National Institute of Mental Health and is currently a neuroscientist in the division of Cognitive Neuroscience and Imaging Genetics at the Lieber Institute for Brain Development at Johns Hopkins Medicine. Dr. Zink spoke to the Upper School students during the day Jean Waller Brune with Dr. Caroline F. Zink, 1995 and to the greater community in the evening about her efforts in determining the biological basis for mental illness. Dr. Zink explained that current medicines for mental illnesses are imperfect, as they do not all target the correct neurotransmitters. Therefore, many patients’ symptoms are not relieved with their prescribed medicine. Dr. Zink’s current research focuses on isolating symptoms one at a time, finding the correlating neurologic activity, and then investigating the genetic influence on that activity. Dr. Zink has made significant progress identifying the neurologic activity associated with lack of motivation, a symptom of many mental illnesses and one that has been stubbornly resistant to current treatment. Through fMRI (functional Magnetic Resonance Imaging), she has been able to measure brain activity and determine that the striatum is the area of the brain involved in motivation. In the experiments she created and ran at the Lieber Institute, she found that healthy people experience higher levels of brain activity in the striatum when highly motivated. Dr. Zink expects that in people with schizophrenia, there is lower brain activity, relative to the norm, in the striatum. Once Dr. Zink and her fellow researchers at the Lieber Institute identify what area of the brain is involved, as they did with motivation and the striatum, they can investigate the genetic influence on that brain activity. The goal is to target these influences and develop effective treatment to prevent and relieve the symptoms. Through new research, there is hope.
About the Sarah Crane Cohen Visiting Scholar in the Humanities Lecture Through the generosity of the late Charles Crane, a Baltimore businessman and philanthropist, an endowment was established at Roland Park Country School in 1993. This fund was created in loving memory of Mr. Crane’s mother, Sarah Crane Cohen, a warm and compassionate woman who possessed a genuine fondness for all people. The Sarah Crane Cohen Visiting Scholar in the Humanities endowment brings a distinguished educator to campus each year.
Hope, Love, Help
In mid-October RPCS held the 5th annual Robinson Health
Colloquium. Generously funded by former Trustee and parent of an alumna James G. Robinson, who believes that parents must be fully engaged in the lives of their daughters, the Robinson Health Colloquium focused this year on adolescent depression awareness. RPCS has partnered with Karen L. Swartz, M.D., founder and program director of the Johns Hopkins University Adolescent Depression Awareness Program (ADAP) to provide a comprehensive program to educate the community about the medical illnesses of depression and bipolar disorder. Depression affects approximately five percent of today’s teenagers and adolescent girls suffer from it at a rate nearly three times that of boys their age. As part of the colloquium, an Upper School Assembly was held featuring a panel including Dr. Swartz, our alumna, current parent and school physician Amy Winkelstein, 1992, and
other psychologists and social workers. Mary Beth Marsden, news anchor at WBAL Radio, moderated the panel and asked each of the panelists to leave the students with a final thought on adolescent depression. Each of the panelists shared a consistent message of hope, love and help. Hope that things can and will get better because medical advances make treatment more accessible and understandable; love for yourself as an important person and for your friends; help because treatment for yourself or someone you care for is available. As part of the Colloquium, Dr. Swartz led a faculty workshop in the afternoon and presented an evening for parents and other interested adults in the community. RPCS is incorporating the ADAP curriculum into Upper School Issues classes in all four grade levels this year. In subsequent years, it will be an integral part of the 9th Grade curriculum.
(L-R) Beth Robinson deVilliers,1996, James G. Robinson, Mary Beth Marsden, Dr. Karen Swartz, Dr. Heather Powell, Dr. Maggie Seide, Dr. Amy Winklestein, 1992, Allyson Michael, LCSW-C and Jean Waller Brune
Roland Park Country School