International Journal of Bio-Inorganic Hybrid Nanomaterials

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Int. J. Bio-Inorg. Hybr. Nanomater., Vol. 4, No. 1 (2015), 5-13

ISSN Print: 2251-8533 ISSN Online: 2322-4142

International Journal of Bio-Inorganic Hybrid Nanomaterials Review on Graphene FET and its Application in Biosensing Mohammad Bashirpour Ph.D., Department of Electrical and Computer Engineering, College of Engineering, University of Tehran, Tehran, Iran

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1. INTRODUCTION Nowadays, the technologies that are applicable to detect protein, DNA (Deoxyribonucleic acid), antigenantibody and etc are time consuming, complex and expensive. For example, detecting DNA sequence with modern techniques needs several processing step. BioPROHFXOH FRQFHQWUDWLRQ DPSOLÂżFDWLRQ E\ 3&5 3RO\PHUDVH &KDLQ 5HDFWLRQ DQG ODEHOLQJ DUH ÂżUVW VWHS Microarrays of different cells utilize to detect different type of solute biomolecule. After that, expensive microarray laser beams are used to read cells [1]. In the past few years, researchers have introduces new electrical signal to eliminate these complex procedures. (*) Corresponding Author - e-mail: m.bashirpour@ut.ac.ir

Electrical detection methods exhibit highly sensitive detection of chemical and biological species because the surface analyte or analyte-analyte bindings occur very close to the channel. ISFET (Ion-Sensitive Field Effect Transistor) has received lots of attention due to their cheap price, small size, fast answer and the possibilities for mass production [2, 3]. ISFET needs no optical reading and abeles to sense biomolecules withRXW WKH QHHG RI 3&5 7KHUHIRUH ,6)(7 PLFURDUUD\V FDQ be used outdoors to control the spread of diseases and environmental pollution. Compatibility of ISFET with Modern microelectronics makes it possible to use am-


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