Ws lifesci2018 by SCIENTIFIC BOOKS INFORMATION

World ScientiďŹ c Connecting Great Minds

2018

LIFE SCIENCES

Connecting Great Minds

Highlights 4

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by Osamu Shimomura (Boston University, USA), Sachi Shimomura & John H Brinegar (Virginia Commonwealth University, USA)

edited by George S Wilson (University of Kansas, USA), Adrian C Michael (University of Pittsburgh, USA)

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edited by Pieter Stroeve (UC Davis Davis), Morteza Mahmoudi (Tehran University of Medical Sciences, Iran & Harvard Medical School, USA)

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by Natalie K Gordon, retired (University of Manitoba, Canada), Richard Gordon (Gulf Specimen Aquarium & Marine Laboratory, USA & Wayne State University, USA)

edited by Giuseppe Arrabito (University of Palermo, Italy), Liqian Wang (Chinese Academy of Sciences, China)

by Jose Russo (Fox Chase Cancer Center, USA)

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edited by Ajaikumar B Kunnumakkara, Ganesan Padmavathi & Nand Kishor Roy (Indian Institute of Technology (IIT) Guwahati, India)

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by Gáspár Jékely (Max Planck Institute for Developmental Biology, Germany)

Life Sciences 2018 page

by Mae-Wan Ho (Institute of Science in Society, UK)

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by Peter Grunwald (University of Hamburg, Germany)

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by Constance E Brinckerhoff (Geisel School of Medicine at Dartmouth, USA)

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edited by Martin L Yarmush (Rutgers University, USA & Harvard Medical School, USA), Alexander Golberg (Tel Aviv University, Israel)

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edited by Martin Grube (University of Graz, Austria), Joseph Seckbach (The Hebrew University of Jerusalem, Israel) & Lucia Muggia (University of Trieste, Italy)

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by Michael Simons (Yale University, USA)

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edited by Song Li (UC Los Angeles), Nicolas by King-Thom Chung (University of L’Heureux (National Institute for Health and Memphis, USA & National Sun Yat-sen Medical Research (INSERM), France), Jennifer University, Taiwan), Jong-Kang Liu (National Elisseeff (Johns Hopkins University, USA) & Sun Yat-sen University, Taiwan) Ngan F Huang (Stanford University, USA)

contents

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BIOCHEMISTRY / BIOLOGICAL CHEMISTRY ........................... 4 BIOENGINEERING ....................................... 6 BIOINFORMATICS / BIOCOMPUTING ........................................ 7 BIOMEDICAL SCIENCES NANO BIOTECHNOLOGY ........................... 8 BIOTECHNOLOGY ....................................... 9 BOTANY / PLANT BIOLOGY....................... 10 CANCER RESEARCH .................................... 10 CELL / MOLECULAR BIOLOGY / STRUCTURAL BIOLOGY .............................. 11 GENERAL LIFE SCIENCES............................. 12 GENETICS & GENOMICS ............................. 14

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HUMAN BIOLOGY ..................................... 16 MICROBIOLOGY / VIROLOGY RESEARCH ................................ 17 NEUROBIOLOGY ......................................... 17 STEM CELLS RESEARCH .............................. 18 LIFE SCIENCES JOURNALS........................... 19 TITLE INDEX ................................................ 21 AUTHOR INDEX .......................................... 21

Life Sciences 2018

BIOCHEMISTRY / BIOLOGICAL CHEMISTRY

This book provides a comprehensive overview of current achievements in biomedical applications of nanotechnology, including stem cell based regenerative medicine, medical imaging, cell targeting, drug delivery, and photothermal/photodynamic cancer therapy. New approaches in early cancer diagnosis and treatment are introduced with extensive experimental results. In particular, some novel materials have been synthesized with new properties that are most effective in cancer therapy. Some of the key issues are also addressed with these recent discoveries such as bio safety and bio degradability, that are essential in the success of nano medicine.

Reviews and Perspectives by Yajun Yan (The University of Georgia, USA) This book provides expert reviews and perspectives on how to engineer microbial metabolism for chemical synthesis. Major metabolic pathways or networks in microbial systems, including glycolysis, citric acid and photosynthesis, are briefly summarized. Feb 2018

Readership: University students and researchers from physics, materials science, engineering, and chemistry. Undergraduate and graduate students will find it a valuable reference book on key topics related to nanomaterials science and technology.

Human DNA Polymerases Biology, Medicine and Biotechnology by Giovanni Maga, Silvio Spadari (Institute of Molecular Genetics IGM-CNR, Italy), Giuseppe Villani (CNRS-Paul Sabatier University, France) & Urich Hübscher (University of Zürich, Switzerland)

200pp 978-981-3149-18-2 978-981-3149-19-9(ebook)

This book focuses on (i) biology of DNA polymerases, (ii) medical aspects of DNA polymerases and (iii) biotechnological applications of DNA polymerases. It is intended for a wide audience from basic scientists, to diagnostic laboratories, to companies and to clinicians, who seek a better understanding and the practical use of these fascinating enzymes. Readership: Academic and industry research scientists, as well as R&D specialists and marketing experts working in biotech and pharmaceutical companies. 400pp 978-981-3226-40-1 978-981-3226-41-8(ebook)

Jan 2018 US$158 US$237

£139 £209

Periodic Tables Unifying Living Organisms at the Molecular Level The Predictive Power of the Law of Periodicity by Antonio Lima-de-Faria (Lund University, Sweden)

The assembled molecular evidence led to the construction of Periodic Tables of living organisms, placing them in a position comparable to the periodicity of the chemical elements. Surprisingly, there are striking resemblances between the periodicities of the chemical elements and those of living organisms. In addition, the two types of Tables increase our insight into the events directing atomic evolution since the periodic law established in chemical elements turns out to be applicable to the periodicity of living organisms. The new Periodic Tables introduce a predictive capacity in biological evolution that before was hardly contemplated. Readership: Researchers in life science 280pp 978-981-3227-00-2 978-981-3227-02-6(ebook)

Jan 2018 US$88 US$132

Tissue Engineering and Nanotheranostics edited by Donglu Shi (University of Cincinnati, USA), Qing Liu (Tongji University, China)

Engineering Microbial Metabolism for Chemical Synthesis

200pp 978-1-78634-429-8

Frontiers in Nanobiomedical Research - Vol 10

£77 £116

Nov 2017 US$110 US$165

£91 £136

Compendium of In Vivo Monitoring in Real-Time Molecular Neuroscience Volume 2: Microdialysis and Sensing of Neural Tissues edited by George S Wilson (University of Kansas, USA), Adrian C Michael (University of Pittsburgh, USA) Consistent with the goals of Volume 1, Volume 2 seeks to provide for scientists in the field of neurobiology a base of bioanalytical techniques that may not be familiar to them. Specific examples are provided and the fundamental basis of the technique is also covered. Readership: Students and researchers in biochemistry, neurobiology, neuroanatomy, biomedical sciences and bioengineering. 450pp 978-981-3220-53-9 978-981-3220-54-6(ebook)

Aug 2017 US$178 US$267

£148 £222

:: Textbook Series in Structural Biology

Structure and Mechanism in Protein Science A Guide to Enzyme Catalysis and Protein Folding 4th Edition by Alan Fersht (University of Cambridge, UK) “A treatment of both enzyme catalysis and protein folding would usually be a multi-author text, edited by at least one expert from each field. But Alan Fersht has been a pioneer in both areas, giving this book a unique and coherent perspective.” Gregory A Petsko Nature Readership: Advanced undergraduates, postgraduates and researchers to the fundamental principle in studying kinetics and mechanism of processes cocerning proteins. 652pp 978-981-3225-18-3 978-981-3225-19-0(pbk)

Aug 2017 US$148 US$68

£130 £60

WORLD SCIENTIFIC World Scientific Lecture and Course Notes in Chemistry - Vol 9

Biophysics and Biochemistry of Protein Aggregation Experimental and Theoretical Studies on Folding, Misfolding, and Self-Assembly of Amyloidogenic Peptides edited by Jian-Min Yuan (Drexel University, USA), Huan-Xiang Zhou (Florida State University, USA) This book reviews current research on the important processes involved in neurodegenerative diseases (e.g. Alzheimer’s disease) and the peptides and proteins involved in the amyloidogenic processes. It covers the design and developments of anti-amyloid inhibitors, and gives readers a fundamental understanding of the underlying oligomerization and aggregation processes of these diseases from both computational and experimental points of view. Readership: Graduate students and researchers studying the field of neurodegnerative diseases and interested in the chemical processes that occur. 328pp 978-981-3202-37-5 978-981-3202-38-2(ebook)

Aug 2017 US$128 US$192

£113 £170

Electrically Active Materials for Medical Devices edited by Syed A M Tofail (University of Limerick, Ireland), Joanna Bauer (Wroclaw University of Technology, Poland) Divided into four parts, this book first introduces the reader to a general overview of electrically active materials in biology and biomedical science and describes important concepts and pioneering discoveries. The second part discusses common types of materials that are known to generate electrical activity and lays the foundation for these materials for use in medical devices. The third part gives examples of where electrically active materials have been examined for device application. The final part looks for upcoming and emerging concepts, tools and methodologies that are expected to shape the future profile of this field of converging science. Readership: Non-specialist readership of professionals, graduate students and researchers in the fields of biomedical engineering, physics, chemistry biology and clinical medicine. 576pp 978-1-78326-986-0 978-1-78326-987-7(ebook)

Oct 2016 US$190 US$285

£158 £237

Luminous Pursuit Jellyfish, GFP, and the Unforeseen Path to the Nobel Prize by Osamu Shimomura (Boston University, USA), Sachi Shimomura & John H Brinegar (Virginia Commonwealth University, USA)

Metallomics

The book provides an engaging account of the life of a dedicated scientist, emphasizing the value of determination in the pursuit of pure scientific knowledge, and showing how a general understanding of science helped him open up new areas of research that have led to unforeseen applications in cell biology and medicine.

“Metallomics is a fascinating small book, easy to read for everybody with a basic knowledge of chemistry and biology, which will undoubtedly stimulate at least some of the readers to explore the field more in depth.” Acta Crystallographica Section D

Readership: Scientists, doctors, students and high school students working with GFP, or studying cell biology or bioluminescence.

Readership: Undergraduate and graduate students in the fields of biochemistry, cell biology, nutrition (trace element research), toxicology, pharmacology, ecology and the effects of metals on human health.

232pp 978-981-3202-15-3 978-981-3202-16-0(pbk) 978-981-3202-17-7(ebook)

Jul 2017 US$68 US$38 US$102

£56 £33 £84

:: Textbook A Primer of Integrated Biometal Sciences by Wolfgang Maret (King’s College London, UK)

156pp 978-1-78326-827-6 978-1-78326-828-3(pbk)

Jul 2016 US$68 US$36

£56 £30

Meaning of Life and the Universe Transforming by Mae-Wan Ho (Institute of Science in Society, UK) This book charts the author’s quest for the meaning of life faced with a dominant knowledge system she regards as incoherent, meaningless, and often acting against people and planet. She shows how contemporary scientific findings across all disciplines already provide an authentic knowledge system that’s coherent with life and the universe. The aim is to transform science thoroughly from inspiration to research to applications that work for people and planet. Readership: Undergraduate students in cell biology, biophysics, biochemistry and quantum mechanics. 500pp 978-981-3108-85-1 978-981-3108-86-8(pbk) 978-981-3108-87-5(ebook)

Mar 2017 US$128 US$45 US$192

£106 £37 £159

NOTABLE BACKLIST BIOLUMINESCENCE: CHEMICAL PRINCIPLES AND METHODS (REVISED EDITION) SHIMOMURA OSAMU (THE MARINE BIOLOGICAL LAB, USA) PROTEIN FOLDING PROBLEM AND ITS SOLUTIONS, THE BEN-NAIM ARIEH (THE HEBREW UNIV OF JERUSALEM, ISRAEL) BORON AND GADOLINIUM NEUTRON CAPTURE THERAPY FOR CANCER TREATMENT HOSMANE NARAYAN S ET AL (NORTHERN ILLINOIS UNIV, USA) ENIGMA OF FERMENT, THE: FROM THE PHILOSOPHER’S STONE TO THE FIRST BIOCHEMICAL NOBEL PRIZE LAGERKVIST ULF (GOTHENBURG UNIV, SWEDEN)

Life Sciences 2018

BIOENGINEERING

Frontiers in Nanobiomedical Research - Vol 7

Multiscale Technologies for Cryomedicine Implementation from Nano to Macroscale edited by Xiaoming He (The Ohio State University, USA), John C Bischof (University of Minnesota, USA)

Semiconductor Quantum Dots and Rods for In Vivo Imaging and Cancer Phototherapy by Maoquan Chu (Tongji University, China) In this book, the QD and QR optical properties, sentinel lymph node mapping, in vivo tumor target imaging, self-illuminating QDs for in vivo imaging, in vivo cancer photothermal therapy and photodynamic therapy, QD-graphene nanosheet, and QD-magnetic hybrid nanocomposites for bioimaging and cancer therapy are discussed.

This is the first book that will provide both an introductory and in-depth account of applying the multiscale technologies in cryomedicine.

Readership: Undergraduate and postgraduate students in bioengineering and with a particular interest in cancer phototherapy.

388pp 978-981-4733-18-2 978-981-4733-19-9(ebook)

350pp 978-981-3142-88-6 978-981-3142-89-3(ebook)

Aug 2017 US$128 US$192

£106 £159

Readership: Doctors and specialists in cryoablation and cryosurgery, researchers and professionals in cryopreservation and cryogenics, nanomedicine and medical device researchers. Aug 2016 US$166 US$249

£138 £207

Bio-Inspired Surfaces and Applications edited by Eddie Y K Ng (NTU, Singapore), Yuehao Luo (The George Washington University, USA)

Frontiers in Nanobiomedical Research - Vol 8

Bioengineering in Wound Healing A Systems Approach edited by Martin L Yarmush (Rutgers University, USA & Harvard Medical School, USA), Alexander Golberg (Tel Aviv University, Israel) “Golberg and Yarmush have set an ambitious goal for themselves in summarizing the current state of the science of wound repair and regeneration. To meet this goal they have assembled many established luminaries and rising stars in the field. In my opinion, they have exceeded their objectives. The book is well organized and comprehensive, presenting students, researchers and clinicians the opportunity to truly understand this complex field and cutting edge interventions.” Robert Sheridan Harvard Medical School

Through millions of years’ natural selection, sharkskin has developed into a kind of dragreducing surface. This book shows how to investigate, model, fabricate and apply sharkskin’s unique surface properties, creating a flexible platform for surface and materials engineers and scientists to readily adopt or adapt for their own bio-inspired materials. Readership: Materials and surface engineers, bioengineers specialising in surfaces and materials, oil and gas pipeline engineers. 600pp 978-981-4704-48-9 978-981-4704-49-6(ebook)

Aug 2016 US$158 US$237

£131 £196

Readership: Bioengineers, scientists, researchers and graduate students outside the field of medicine. 396pp 978-981-3144-57-6 978-981-3144-58-3(ebook)

May 2017 US$158 US$237

Injectable Hydrogels for Regenerative Engineering £139 £209

Perspectives in Micro- and Nanotechnology for Biomedical Applications edited by Juliana M Chan, Chenjie Xu (NTU, Singapore)

This book provides a broad perspective into the basic principles and applications of today’s most promising micro- and nanotechnologies, and is an up-to-date reference book for researchers. It is also suitable for undergraduate and graduate students, patent lawyers and investors who are interested in the latest innovations taking place in the biomedical sciences, many of which may dramatically improve the lives of millions of people. Readership: Medical students; graduate students, scientists, researchers and investors interested in biomedical sciences, bioengineering and pharmacology/ drug delivery, patent lawyers. 312pp 978-1-78326-960-0 978-1-78326-961-7(ebook)

Sept 2016 US$118 US$177

£98 £147

edited by Lakshmi S Nair (University of Connecticut, USA) The book will explain synthetic approaches towards developing injectable hydrogels, and the clinical implications and applications of injectable hydrogels for engineering various tissues. It is the first of its kind to bring together the fields of injectable hydrogels and regenerative engineering to give a perspective of the emerging therapeutic strategies for a wide audience. Readership: Professionals, undergraduate and graduate students in the field of bioengineering and biological chemistry. 448pp 978-1-78326-746-0 978-1-78326-747-7(ebook)

Feb 2016 US$166 US$249

£138 £207

WORLD SCIENTIFIC

Analysis of Biological Systems

BIOINFORMATICS / BIOCOMPUTING / COMPUTATION BIOLOGY

by Corrado Priami, Melissa J Morine (University of Trento, Italy)

This book at the latest research on modelling of biochemical pathways within synapses, and provides a clear background for the study of mathematical models related to systems biology.

“This book provides extensive coverage of major tools and approaches used in the modeling and simulation of molecular biological systems. Quantitative scientists will find a very thorough and well-written introduction to cell and molecular biology in the second chapter to get familiarized with the fundamentals of molecular biological systems. The book can also be seen as a useful repository for commonly used algorithms in the field because they are isolated and described in their own sections within chapters, as is also done for definitions, key terms, and concepts. The organization of the volume is the result of several years of teaching to advanced undergraduate students and can thus be used as a bridge to bring undergraduate students in mathematics and computer science to the growing and fascinating fields of cell and systems biology.” The Quarterly Review of Biology

Readership: Postgraduate students and researchers in computational systems biology.

Readership: Graduate in computer science, physics, mathematics or engineering or biology-related fields.

335pp 978-1-78634-337-6 978-1-78634-338-3(ebook)

432pp 978-1-78326-687-6 978-1-78326-688-3(ebook)

Series on Advances in Bioinformatics and Computational Biology - Vol 10

Computational Systems Biology of Synaptic Plasticity Modelling of Biochemical Pathways Related to Memory Formation and Impairment by Don Kulasiri, Yao He (Lincoln University, New Zealand)

Aug 2017 US$138 US$207

£121 £182

Bioinformatics

Methods and Applications edited by Torsten Schwede (Swiss Institute of Bioinformatics & Biozentrum University of Basel, Switzerland), Manuel C Peitsch (Novartis Institutes of BioMedical Research, Switzerland)

“The language used is relatively easy to understand for non-bioinformaticians. Sufficient simplifications have been successfully done in describing complex concepts while still maintaining clarity. This is the book that I have been looking for. As a molecular geneticist starting to use NGS I find this book informative and practical for priming me with simple bioinformatics knowledge and skills.” Teguh Haryo Sasongko, MD, PhD Senior Lecturer, Human Genome Center, School of Medical Sciences, Universiti Sains Malaysia Sept 2017 US$98 US$147

£148 £222

Computational Structural Biology

A Practical Handbook of Next Generation Sequencing and Its Applications edited by Lloyd Low (Perdana University Centre for Bioinformatics, Malaysia), Martti Tammi (Sime Darby, Malaysia)

250pp 978-981-3144-74-3 978-981-3144-75-0(ebook)

Mar 2015 US$178 US$267

£81 £121

“Undergraduates and master students focussed on structural bioinformatics will clearly benefit from the breadth of topics covered ... PhD students will find chapters in their area extremely helpful in getting a concise overview of the state of play of their field, references to key reviews and the challenges that lie ahead. Finally, post-docs and professors will be able to explore tangential areas of their immediate research and get a firm grasp of the larger field by having such a broad spectrum of material presented that is well written and up-to-date.” Crystallography Reviews Readership: Academics, scientists in bioinformatics, computational, biocomputing, proteomics, cell biology and pharmacology. 792pp 978-981-277-877-2 978-981-277-878-9(ebook)

Biocomputing 2017 Proceedings of the Pacific Symposium Kohala Coast, Hawaii, USA, 4 – 8 January 2017 edited by Russ B Altman, Tiffany A Murray & Teri E Klein (Stanford), A Keith Dunker (Indiana University, USA), Lawrence Hunter (University of Colorado Health Sciences Center, USA), Marylyn D Ritchie (The Pennsylvania State University, USA)

July 2008 US$222 US$332

£184 £276

NOTABLE BACKLIST BIOLOGICAL DATA MINING AND ITS APPLICATIONS IN HEALTHCARE LI XIAOLI ET AL (A*STAR & NTU, S’PORE) COMPUTATIONAL NEUROANATOMY: THE METHODS CHUNG MOO K (UNIV OF WISCONSIN-MADISON, USA)

The Pacific Symposium on Biocomputing (PSB) 2017 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. 668pp 978-981-3207-80-6 978-981-3207-81-3(ebook)

Jan 2017 US$198 US$297

£164 £246

Visit : http://www.worldscientiﬁc.com/page/lifesci/new-titles for more titles and sample chapters

Life Sciences 2018

BIOMEDICAL SCIENCES

From Hybrid DNA Nanostructures to Functional Devices edited by Giuseppe Arrabito (University of Palermo, Italy), Liqian Wang (Chinese Academy of Sciences, China)

:: Textbook Computational Chemotaxis Models for Neurodegenerative Disease by William E Schiesser (Lehigh University, USA) The mathematical model presented in this book, based on partial differential equations (PDEs) describing attractant-repellent chemotaxis, is offered for a quantitative analysis of neurodegenerative disease (ND), e.g., Alzheimer’s disease (AD). The model is a representation of basic phenomena (mechanisms) for diffusive transport and biochemical kinetics that provides the spatiotemporal distribution of components which could explain the evolution of ND, and is offered with the intended purpose of providing a small step toward the understanding, and possible treatment of ND. 172pp 978-981-3207-45-5 978-981-3208-91-9(pbk)

May 2017 US$98 US$58

£81 £48

This book provides a concise and rigorous description for the fabrication of various types of functional nanostructures by optimized softwareaided high-yield synthesis. Following this is the explanation of methods to decorate these nanostructures with molecules such as proteins, metal nanoparticles or bioorganic moieties covalently bonded onto DNA via self-assemblage processes. Readership: Non-specialists, undergraduate students and researchers who are interested in learning the basics of DNA nanotechnology. 250pp 978-1-78634-379-6 978-1-78634-380-2(ebook)

Nov 2017 US$98 US$147

£86 £129

World Scientific Series in Nanoscience and Nanotechnology - Vol 11

Nanobioceramics for Healthcare Applications

Molecular Bioelectronics

edited by Eng San Thian (NUS, Singapore), Jie Huang (University College London, UK) & Mamoru Aizawa (Meiji University, Japan)

The 19 Years of Progress 2nd Edition by Nicolini Claudio (University of Genoa, Italy)

This book provides a comprehensive coverage on nanobioceramics and their potential applications in healthcare. Ground-breaking new discoveries in bioceramics and their properties have meant an increasing interest in the development of how this can be related to nanobiomaterials, and in treating various conditions from osteoporosis to surgical dentistry.

Molecular bioelectronics is a field in strong evolution at the frontier of life and materials sciences. The term is utilized in a broad context to emphasize a unique blend of electronics and biotechnology which is seen as the best way to achieve many objectives of industrial and scientific relevance, including biomolecular engineering, bioelectronic devices, materials and sensors capable of optimal hardware efficiency and intelligence and molecular miniaturization.

Readership: Professionals and students in materials science and engineering; medical professionals searching for state-of-the-art techniques and treatments available in nanobioceramics. 316pp 978-1-78634-133-4 978-1-78634-134-1(ebook)

Feb 2017 US$138 US$207

£115 £173

NANO BIOTECHNOLOGY World Scientific Series: From Materials towards Biomedical Devices - Vol 1

Drug Delivery Systems edited by Pieter Stroeve (UC Davis), Morteza Mahmoudi (Tehran University of Medical Sciences, Iran & Harvard Medical School, USA)

DNA Nanotechnology for Bioanalysis

The book provides a comprehensive overview of the recent developments on “smart” targeting and drug delivery systems with a variety of carriers like nanoparticles, membranes, and hydrogels. It contains detailed descriptions on the recent trends in this field in the ongoing battle with catastrophic diseases like cancer.

336pp 978-981-4725-84-2 978-981-4725-85-9(ebook)

May 2016 US$150 US$225

£125 £187

Nanomaterials for Tumor Targeting Theranostics A Proactive Clinical Perspective edited by Mingqian Tan, Aiguo Wu (Chinese Academy of Sciences, China) In this book, the most recent progress of main nanomaterials and their applications in tumor targeting theranostics is presented. It summarizes the recent advances of current principal nanomaterials in tumor theranostics, including magnetic nanomaterials, quantum dots, mesoporous silica nanoparticles, gold nanomaterials, polymeric nanosystem, carbon nanomaterials, lipopolyplex nanoparticles, microbubbles, upconversion nanomaterials and dendrimers.

Readership: Nanotechnologists, biomedical engineers, chemical engineers, materials scientists, biotechnology researchers, chemists, biological scientists, cell physiologists, medical scientists, gene therapists.

Readership: Advanced undergraduates, graduates, chemists, materials scientists, biomedical engineers, pharmacologists, biologists, doctors and oncologists in nanomaterials, nanobiotechnology, nanomedicine, tumor theranostics, tumor targeting, tumor diagnosis, tumor imaging, and tumor therapy.

350pp 978-981-3201-04-0 978-981-3201-05-7(ebook)

432pp 978-981-4635-41-7 978-981-4635-42-4(ebook)

Dec 2017 US$125 US$188

£104 £156

Apr 2016 US$166 US$249

£138 £207

WORLD SCIENTIFIC

BIOTECHNOLOGY

by Judi Sture

Cultured Meat Producing Meat without Animals by Stellan Welin (Linköping University, Sweden), Henk P Haagsman (Utrecht University, The Netherlands) This book features an in-depth analysis of possible technical solutions for cultured food production and future development as well as a discussion on the benefits for health and issues of public acceptance. Readership: Scientists and students in the areas of food science, tissue engineering, environmental studies, conservation/ wilderness studies; Professionals; Policy makers in the area of agriculture and philosopher/ ethicists; General Public: anyone caring about future food production, the environment and animal ethics. 200pp 978-981-4632-73-7 978-981-4632-74-4(ebook)

May 2018 US$106 US$159

£88 £133

Synthetic Biology and Bioweapons by Filippa Lentzos With: Catherine Jefferson, Claire Marris, Nikolas Rose (King’s College London, UK)

Readership: Professional scientists, contract researchers, principal investigators, project leaders, journal editors, funders, tutors or students of the sciences. 332pp 978-1-78634-091-7 978-1-78634-092-4(pbk) 978-1-78634-093-1(ebook)

Nov 2016 US$78 US$38 US$117

£65 £32 £97

Biotechnology and Medical Science

This book is an all-embracing review of biotechnology, biomedical engineering, bioinformatics, pharmacy and medicinal chemistry, and biopharmaceutical technology. Existing theories and the latest findings are discussed.

Through an accessible and engaging narrative that highlights key messages, questions for discussion and classroom exercises, readers are expertly led through the complex technical, historical, social, political and legal landscape at the intersection of synthetic biology and security. Readership: Undergraduates, postgraduates and established researchers in the field of life sciences; policymakers; political scientists; research funders; sociologists. May 2018 US$78 US$39

This book is designed to be an easy-to-use guide to understanding the ethical and biosecurity implications of life science research. It provides a framework that will enable scientists, lab managers, researchers, students and teachers to anticipate how research may be used to cause harm, and to identify the steps that can be taken to minimise this risk.

Proceedings of the 2016 International Conference on Biotechnology and Medical Science 2016 International Conference on Biotechnology and Medical Science Nanjing, Jiangsu, China, 16 – 17 April 2016 edited by Yong Zhang (NUS, Singapore)

:: Textbook

180pp 978-1-78326-765-1 978-1-78326-766-8(pbk)

The Ethics and Biosecurity Toolkit for Scientists

£65 £32

Readership: Researchers, engineers, academics, and industry professionals in the fields of biotechnology and medical science. 700pp 978-981-3145-86-3 978-981-3145-87-0(ebook)

Oct 2016 US$245 US$368

£203 £305

NOTABLE BACKLIST SYNTHETIC BIOLOGY: A LAB MANUAL FORSTER ANTHONY C, LILJERUHM JOSEFINE & GULLBERG ERIK (UPPSALA UNIV, SWEDEN)

Biocatalysis Biochemical Fundamentals and Applications 2nd Edition by Peter Grunwald (University of Hamburg, Germany)

PLENTY OF ROOM FOR BIOLOGY AT THE BOTTOM: AN INTRODUCTION TO BIONANOTECHNOLOGY (2ND EDITION) GAZIT EHUD ET AL (TEL AVIV UNIV, ISRAEL)

In this book, all Chapters have been updated considering relevant literature and recent developments until 2016 together with application oriented examples with a focus on Industrial Biocatalysis. Newly treated topics comprise among others systems metabolic engineering approaches, metagenome screening, new tools for pathway engineering, and de-novo computational design as actual research areas in biocatalysis. Information about different aspects of RNA technologies, and completely new Chapters on ‘Fluorescent Proteins’ and ‘Biocatalysis and Nanotechnology’ are also included.

BIODIVERSITY, NATURAL PRODUCTS AND CANCER EFFERTH THOMAS ET AL (UNIV MAINZ, GERMANY) ORCHID BIOTECHNOLOGY CHEN HONG-HWA ET AL (NAT’L CHENG KUNG UNIV, TAIWAN) ESSENTIAL BIOTECH INVESTMENT GUIDE, THE: HOW TO INVEST IN THE HEALTHCARE BIOTECHNOLOGY AND LIFE SCIENCES SECTOR TANG CHILUNG MARK (WORLD TECHNOLOGY INVEST GROUP CORPORATION, USA)

eBook is available!

Readership: Advanced undergraduate and graduate students in biology, chemistry, biochemistry and medicine. Biochemists, biologists and chemists. 1200pp 978-1-78326-907-5 978-1-78326-908-2(pbk)

Sept 2017 US$225 US$98

£187 £81

Order online www.worldscientiﬁc.com

Life Sciences 2018

BOTANY / PLANT BIOLOGY

CANCER RESEARCH

Biological Shape Analysis

The Training of Cancer Researchers

Proceedings of the 4th International Symposium 4th International Symposium on Biological Shape Analysis (ISBSA) School of Dentistry, UCLA, USA, 19 – 22 June 2015 edited by Pete E Lestrel (UCLA)

by Jose Russo (Fox Chase Cancer Center, USA) This book discusses a number of topics that address these challenges and the origins of cancer research from a cultural and historical perspective.

These proceedings represent state-of-the-art research in the field of biology, broadly-based, that deal with the quantitative analysis of the shape of the biological form. These numerical analyses include fourier analytic methods, wavelets, neural networks, machine vision, machine learning, median axis transforms, spectral clustering, genome-wide association studies, 3D surface mapping, as well as more traditional morphometric approaches. Studies included are drawn from research in agricultural genetics, anatomy, anthropology, botany, dentistry, entomology, forensics, human evolution, paleontology, primatology, to name a few. Readership: Graduate students and researchers in biological science and agricultural genetics. 456pp 978-981-3224-58-2 978-981-3225-70-1(ebook)

Jun 2017 US$198 US$297

£174 £261

Algal and Cyanobacteria Symbioses edited by Martin Grube (University of Graz, Austria), Joseph Seckbach (The Hebrew University of Jerusalem, Israel) & Lucia Muggia (University of Trieste, Italy) This book presents a compilation of recent, updated research in fields of diverse symbioses, including in marine, freshwater, and terrestrial habitats. It gives a comprehensive overview of algal and cyanobacteria symbioses, including reviews on their diversity and information on symbiotic specificity and stress tolerance. Also covered is a review of regulatory mechanisms in the communication between symbiotic partners. Readership: Researchers, professors and advanced students of biochemistry, mycology, cell biology, botany, algae-specific anatomy and physiology, and plant-microbe interactions. 680pp 978-1-78634-057-3 978-1-78634-058-0(ebook)

Feb 2017 US$198 US$297

£164 £246

Life Sciences Collection: Books, journals and sample chapters

Readership: Graduate and medical students, postdoctoral and research fellows, and scientists looking to go into cancer research; policy makers. 212pp 978-981-3203-14-3 978-981-3203-15-0(ebook)

Jun 2017 US$68 US$102

£60 £90

Fusion Genes and Cancer edited by Ajaikumar B Kunnumakkara, Ganesan Padmavathi & Nand Kishor Roy (Indian Institute of Technology (IIT) Guwahati, India) This book is first of its kind and aims at giving a detailed idea on the formation of gene fusions and their importance in the development and progression of cancer; techniques to identify novel gene fusions; and therapeutics available to target various fusion proteins and their impact in cancer therapy by compiling the information from the literature available till date. Readership: Scientists working in the field of cancer biology, cancer genomics and proteomics. Specialists and researchers in diverse fields of disease pathogenesis as it provides collective information about fusion genes and cancer from the basics to the targeted therapies. 432pp 978-981-3200-93-7 978-981-3200-94-4(ebook)

Jun 2017 US$148 US$222

£130 £195

Handbook of Photodynamic Therapy Updates on Recent Applications of Porphyrin-Based Compounds edited by Ravindra K Pandey, Thomas J Dougherty (Roswell Park Cancer Institute, USA), David Kessel (Wayne State University, USA) The main objective of this book is to present the recent applications of photodynamic therapy (PDT) in treating cancer and other diseases. The limitations associated with current PDT agents, and the synthetic designs that have been used in various laboratories are also discussed. The utility of certain tumor-avid agent for cancer imaging (fluorescence, PET, MRI) is also summarized. The book also includes the use of delivery vehicles, including nanoparticles in improving the tumor-specificity of the desired agents. The book is basically focused on the translational approach of drug development. By providing certain specific examples, a clear concept of moving a “product” from the bench to bed-side is also discussed. Readership: Oncologists, pharmacologists, chemists, biologists, physicists, and biochemists involved in cancer research, as well as graduate-level students in these disciplines.

http://bit.ly/wspc-lifesci

564pp 978-981-4719-64-3 978-981-4719-65-0(ebook)

May 2016 US$203 US$305

£179 £268

WORLD SCIENTIFIC

CELL / MOLECULAR BIOLOGY / STRUCTURAL BIOLOGY Rho GTPases Molecular Biology in Health and Disease edited by Philippe Fort, Anne Blangy (French National Center for Scientific Research (CNRS), France) This book is divided into three parts. Part 1 gives an evolutionary perspective of the Rho family, its atypical members, and an overview of how Rho activity is regulated. Part 2 addresses two important aspects of multicellularity controlled by Rho-dependent pathways, namely, cell-cell interactions and mechanotransduction. Part 3 explores several examples of the variety of pathophysiological processes controlled by Rho signaling, and gives a successful example of translational research, from the inhibition of Rho activation to the development of new molecules against osteoporosis. 300pp 978-981-3228-78-8 978-981-3228-79-5(ebook)

Dec 2017 US$125 US$188

£110 £165

The Cell Language Theory Connecting Mind and Matter by Sungchul Ji (Rutgers University, USA)

£123 £160

Feb 2017 US$148 US$222

£123 £185

This book will serve as the preeminent text book on the topic of “base excision repair”, a key DNA repair pathway that protects cells from most spontaneous forms of DNA damage, including oxidative lesions that arise both in the nuclear and mitochondrial genomes. Readership: Researchers, academics, scientists and clinicians, particularly for radiological and medical oncologists, epidemiologists, cancer prevention specialists, and graduate students in cancer biology

Sculpting the Human Body by Constance E Brinckerhoff (Geisel School of Medicine at Dartmouth, USA)

824pp 978-981-4719-72-8 978-981-4719-73-5(ebook)

This volume summarizes the salient features and functions of Matrix Metalloproteinases (MMPs) and applies this information in a practical manner in order to understand how they contribute to normal physiology and pathology of selected diseases. Chapters by noted clinicians Jean-Michel Dayer, MD in rheumatology, Jian Cao, MD in oncology, and Peter Libby, MD in cardiology, represent important practical and clinically-oriented contributions. Readership: Researchers and clinicians interested in the applications of Matrix Metalloproteinases (MMPs). Jul 2017 US$138 US$207

Readership: People working in the field of FGF/FGF signaling: investigators, students and clinicians; vascular biologists and trainees in vascular biology. Graduate courses on FGF biology, RTFs or vascular biology.

Molecular Mechanisms and Role in Disease Development and Therapeutic Design edited by David M Wilson III

Matrix Metalloproteinases in Health and Disease

296pp 978-981-3207-54-7 978-981-3207-55-4(ebook)

The fibroblast growth factor (FGF) family of ligands and the corresponding family of FGF receptor tyrosine kinases comprise one of the most versatile and diverse growth factor signaling families in vertebrates, found virtually in every tissue and cell type where they regulate metabolic and physiologic function, maintain tissue homeostasis, and mediate injury response, tissue repair, and regeneration. As a result, FGFs play critical roles in a wide variety of normal biological and abnormalities in FGF signaling can lead to a variety of disease states from developmental malformations, to atherosclerosis, pulmonary hypertension and cancer among many others. A thorough understanding of this system is necessary for critical insights into both normal and disease biology and is essential to development of rationale therapeutic strategies aimed at treatment of FGFdependent diseases states.

The Base Excision Repair Pathway

Readership: Students, researchers and practitioners of the biomedical sciences and mind-body research and consciousness studies. Nov 2017 US$148 US$192

FGF Biology and Therapeutics by Michael Simons (Yale University, USA)

284pp 978-981-3143-36-4 978-981-3143-37-1(ebook)

It describes the first comprehensive molecular theory of the genotype-phenotype coupling based on two key theoretical concepts: (i) the conformon, the conformational wave packet in biopolymers carrying both the free energy and genetic information; and (ii) the intracellular dissipative structures, the chemical concentration waves inside the cell that serve as the immediate drivers of all cell functions.

450pp 978-1-84816-660-8 978-1-84816-661-5(ebook)

Fibroblast Growth Factors: Biology and Clinical Application

£115 £173

Feb 2017 US$198 US$297

£164 £246

Vascular Smooth Muscle Structure and Function in Health and Disease edited by Chi-Ming Hai (Brown University, USA)

11 This book presents key concepts in the structure and function of vascular smooth muscle cells in health and disease. Supplemental reading may be drawn from the extensive references listed at the end of each chapter. Readership: Reference for graduate students, post-doctoral fellows, and scientists who work on vascular biology, as well as physicians who work on vascular medicine. 308pp 978-981-3144-05-7 978-981-3144-06-4(ebook)

Dec 2016 US$135 US$203

£112 £168

Life Sciences 2018 :: Textbook

:: Bestseller

Series in Structural Biology - Vol 8

Embryogenesis Explained

Textbook of Structural Biology

by Natalie K Gordon, retired (University of Manitoba, Canada), Richard Gordon (Gulf Specimen Aquarium & Marine Laboratory, USA & Wayne State University, USA)

2nd Edition by Anders Liljas (Lund University, Sweden), Lars Liljas (Uppsala University, Sweden), Miriam-Rose Ash (The University of Sydney, Australia), Göran Lindblom (Umeå University, Sweden), Poul Nissen & Morten Kjeldgaard (Aarhus University, Denmark)

“Embryogenesis Explained is a pleasure to read, presenting difficult concepts clearly and effectively. It carries deep biological thought, and whether one agrees with the differentiation waves theory or not, it is inspiring and stimulating.”

“Overall, the quality and feel of the book is of a handsomely produced volume.” Crystallography Reviews

Prof Jean Jacques Kupiec Centre Cavaillès, École Normale Supérieure, France

Readership: Undergraduate and graduate students in structural biology, chemistry, biochemistry, biology and medicine.

Readership: General public and professionals interested in developmental biology.

612pp Nov 2016 978-981-3142-46-6 US$178 978-981-3142-47-3(pbk) US$95 Series in Structural Biology - Vol 6

784pp 978-981-4350-48-8 978-981-4350-50-1(ebook)

£148 £79

Nov 2016 US$198 US$297

£164 £246

Structure and Action of Molecular Chaperones Machines that Assist Protein Folding in the Cell by Lila M Gierasch (University of Massachusetts, Amherst, USA), Arthur L Horwich (Yale School of Medicine, USA), Christine Slingsby (University of London, UK), Sue Wickner (National Cancer Institute, USA) & David Agard (UC San Francisco)

Nobel Prizes and Notable Discoveries by Erling Norrby (The Royal Swedish Academy of Sciences, Sweden)

This unique volume reviews the beautiful architectures and varying mechanical actions of the set of specialized cellular proteins called molecular chaperones, which provide essential kinetic assistance to processes of protein folding and unfolding in the cell. Readership: Cell and molecular biologists, biochemists and biophysicists, nanoscientists. 328pp 978-981-4749-32-9 978-981-4749-33-6(ebook)

Oct 2016 US$150 US$225

£125 £187

GENERAL LIFE SCIENCES Self and the Phenomenon of Life A Biologist Examines Life from Molecules to Humanity by Ramon Lim (University of Iowa, USA)

“In this, his third book on Nobel prizes in the life sciences, Erling Norrby again combines some of the detailed discussions of the Nobel Prize Committees with his own brilliant review of the intellectual history of the field. In the current volume Norrby covers not only the major prizes in neuroscience given in the 1960s, but he also traces the history of neuroscience from its onset to almost the present day. This is an extraordinary contribution to the Nobel Prize and to the intellectual history of modern biological science.” Eric Kandel Nobel Laureate in Physiology or Medicine, 2000 Readership: General public interested in biological science. 580pp 978-981-3144-63-7 978-981-3144-64-4(pbk) 978-981-3144-65-1(ebook)

Nov 2016 US$78 US$38 US$117

£65 £32 £97

eBook is available!

The book describes a common ground between the biology of life and the humanity of life without compromising either discipline. It attempts to bridge the gap between our “two cultures” — the sciences and the humanities, as advocated by C P Snow fifty years ago. This book connects our meager existence to the entire living world and the universe, physically and spiritually, through the simple perspective of “self, “ being defined as a system that seeks its own perpetuation.

Order online www.worldscientiﬁc.com

Readership: Students and professionals in life science and medicine. 310pp 978-981-3203-77-8 978-981-3203-78-5(pbk) 978-981-3203-79-2(ebook)

Aug 2017 US$75 US$38 US$113

£62 £32 £93

View our Life Science Page at

http://www.worldscientific.com/page/lifesci

WORLD SCIENTIFIC

Biophysics of Consciousness

Cures vs Profits

A Foundational Approach edited by Roman R Poznanski (The Rockefeller University, USA & Universiti Teknologi Malaysia, Malaysia), Jack A Tuszynski (University of Alberta, Canada) & Todd E Feinberg (Icahn School of Medicine at Mount Sinai, USA & Mount Sinai Beth Israel Medical Center, USA)

Successes in Translational Research by James Lyons-Weiler (Institute for Pure and Applied Knowledge, USA)

“First book to go beyond a merely neural to an urgently needed truly biophysical and henceforth natural basis of consciousness.” Georg Northoff, MD, PhD, FRCPC Canada Research Chair in Mind, Brain Imaging and Neuroethics This volume unites the crème de la crème of physicists, neuroscientists, and psychiatrists in the attempt to understand consciousness through a foundational approach encompassing ontological, evolutionary, neurobiological, and Freudian interpretations with the focus on conscious phenomena occurring in the brain. By integrating the perspectives of these diverse disciplines with the latest research and theories on the biophysics of the brain, the book tries to explain how consciousness can be an adaptive and causal element in the natural world. Readership: Researchers in neuroscience, cognitive science, psychology, biophysics and quantum physics 664pp 978-981-4644-25-9 978-981-4644-26-6(ebook)

Oct 2016 US$190 US$285

£158 £237

“This book is devoted to those interested in the progress of clinical medicine, allowing everyone to critically review recent successes in biomedical research, and to formulate a personal opinion based on the facts reported. Enjoyable to read and informative, this is a book that typically leaves the reader thinking seriously about the subject discussed, even long after finishing reading.” Acta Crystallographica. 360pp 978-981-4730-13-6 978-981-4730-14-3(pbk) 978-981-4730-15-0(ebook)

May 2016 US$39 US$18 US$59

£32 £15 £48

Myths and Verities in Protein Folding Theories by Arieh Ben-Naim (The Hebrew University of Jerusalem, Israel) This book tells the story of a whole field of research which went disastrously wrong in many different directions when the wrong tools were used and the wrong targets aimed at, to solve a problem.

Series in Structural Biology - Vol 5

The Struggles and Dreams of Robert Langer

448pp 978-981-4725-98-9 978-981-4725-99-6(pbk)

by Robert Langer (MIT, USA) edited by Shuguang Zhang (MIT, USA)

Mar 2016 US$68 US$34

:: Bestseller

This book provides a glimpse into the life and work of Robert Langer, an amazing scientist, inventor and entrepreneur.

How to Read and Critique a Scientific Research Article

Readership: Historians, scientists, educators, undergraduates and graduates, biographers.

Notes to Guide Students Reading Primary Literature (with Teaching Tips for Faculty Members) by Foong May Yeong (NUS, Singapore)

392pp 978-981-4749-03-9 978-981-4749-04-6(pbk)

This guidebook provides a structured approach to reading a research article, guiding the reader step-by-step through each section.

Jul 2016 US$110 US$48

£91 £40

Emperor of Enzymes A Biography of Arthur Kornberg, Biochemist and Nobel Laureate by Errol C Friedberg (University of Texas Southwestern School of Medicine, USA) This book chronicles the life and work of the late Arthur Kornberg, one of the premier biochemists in the world, who discovered the enzyme DNA polymerase, a key enzyme required for the biosynthesis of DNA. Readership: Students and researchers in biochemistry and enzymology. 340pp 978-981-4699-80-8 978-981-4699-81-5(pbk) 978-981-4699-82-2(ebook)

Jul 2016 US$70 US$36 US$105

£56 £28

£58 £30 £88

116pp 978-981-4579-16-2(pbk) 978-981-4579-17-9(ebook)

Mar 2014 US$28 US$42

£23 £35

:: Bestseller Nobel Prizes and Nature’s Surprises by Erling Norrby (The Royal Swedish Academy of Sciences, Sweden)

“This book describes and explains one of the most important discoveries of the 20th century. It is a seminal work, that scholars of the History of Science will use to be able to understand how science evolves. Young scientists will find this book a valuable resource.” Sir Aaron Klug Nobel laureate in Chemistry, 1982 472pp 978-981-4520-98-0 978-981-4520-99-7(pbk) 978-981-4522-00-7(ebook)

Dec 2013 US$98 US$58 US$147

£81 £48 £121

Life Sciences 2018

GENETICS & GENOMICS

Quantitative Genetics and Its Connections with Big Data and Sequenced Genomes by Charles J Mode (Drexel University, USA)

The Story of Genetics, Development and Evolution A Historical Dialogue by Gáspár Jékely (Max Planck Institute for Developmental Biology, Germany)

The book gives an overview of developments in Quantitative Genetics and variance component analysis in an era of Big Data and Sequenced Genomes.

This unique story offers an introductory conversation to genetics, embryology and evolution, taking us on a historical journey of biology through the ages.

Readership: Graduate students and researchers in statistics, biostatistics and researchers in genetics.

Readership: Students of biology, philosophy and medicine.

180pp 978-981-3140-67-7 978-981-3140-68-4(pbk)

500pp 978-1-78634-252-2 978-1-78634-253-9(pbk) 978-1-78634-254-6(ebook)

Oct 2017 US$148 US$78 US$222

£123 £65 £185

Jan 2017 US$68 US$36

£56 £30

Unravelling Complexities in Genetics and Genomics Impact on Diagnosis Counseling and Management by Moyra Smith (UC Irvine)

The Life of Professor Robert Hugh Pritchard The Rise of Genetics at Leicester edited by Arieh Zaritsky (Ben-Gurion University of the Negev, Israel) Colleagues and former students of the late Professor Pritchard (aka Bob), an eminent UK geneticist, have gathered memories about his scientific and personal life. 212pp 978-981-3203-73-0 978-981-3203-74-7(pbk) 978-981-3203-75-4(ebook)

Feb 2017 US$68 US$34 US$102

£56 £28 £84

Epigenetics in Human Reproduction and Development

This book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.

Dec 2016 US$99 US$149

£87 £131

Security Science and Technology - Vol 2

Handbook of Forensic Genetics Biodiversity and Heredity in Civil and Criminal Investigation edited by Antonio Amorim (University of Porto, Portugal), Bruce Budowle (University of North Texas Health Science Center, USA)

Readership: Professors, scientists, trainees, and residents in the field of reproduction and epigenetics. Feb 2017 US$138 US$207

Readership: Physicians, nurses, genetic counselors, graduate students in genetics and genomics. 432pp 978-981-4759-46-5 978-981-4759-47-2(ebook)

edited by Anna K Naumova, Teruko Taketo (McGill University, Canada)

304pp 978-981-3144-26-2 978-981-3144-27-9(ebook)

This book reviews recent advances in defining genetic and genomic factors that play important roles in diseases in humans. It includes discussions on new technologies in DNA and RNA sequencing, genome analysis, and bioinformatics applied to the study of patients with specific disorders and to normal populations, and illustrates how modern molecular techniques can improve diagnoses and enable the design of specific targeted therapies and methods of prevention. Additional emphasis is placed on the genetic variants and genomic risk factors related to the development of complex common disorders, including neurobehavioral and neurocognitive disorders in children and adults and late onset disorders in adults, including atherosclerosis, type 2 diabetes, cancer, and neurodegenerative disorders.

£115 £172

This advanced handbook intends to overcome the historical barriers between the scientific fields of legal medicine, biodiversity and conservation, and food analysis by presenting a unifying, global perspective on the implications of genetic analyses on forensic affairs. This global perspective is presented in three parts: modes of inheritance and reproduction and taxonomic implications; current technological approaches and future perspectives; and a comprehensive systematization of the types of applications and organisms. Finally, a critical revision of the current investigative/expert systems and future perspectives is undertaken. Readership: Forensic scientists and advanced graduate students in the field.

Contact sales@wspc.com.sg or visit website http://www.worldscientific.com/page/inspection-copy

652pp 978-1-78634-077-1 978-1-78634-078-8(ebook)

Oct 2016 US$148 US$222

£123 £183

WORLD SCIENTIFIC

:: Bestseller

LIFE SCIENCES JOURNALS

Information Theory and Evolution 2nd Edition by John Scales Avery (University of Copenhagen, Denmark)

Biophysical Reviews and Letters http://www.worldscientific.com/brl

This book discusses the phenomenon of life, including its origin and evolution (and also human cultural evolution), against the background of thermodynamics, statistical mechanics, and information theory. Readership: Students, professionals, and all readers with scientific or engineering training regardless of field. 276pp 978-981-4401-22-7 978-981-4401-23-4(pbk) 978-981-4401-24-1(ebook)

Jul 2012 US$84 US$48 US$126

£70 £40 £104

How New Humans Are Made Cells and Embryos, Twins and Chimeras, Left and Right, Mind/Self/Soul, Sex, and Schizophrenia by Charles E Boklage (East Carolina University, USA)

Journal of Biological Systems

In this book, when technical terminology is the only way, or the best way, to say what needs to be said, it is defined and explained — making the words a worthwhile part of what is here to be learned.

http://www.worldscientific.com/jbs

This book defines its own new field. We cannot claim to understand how anything [human] works [as human], with no effort at understanding the emergence of its form and functions. Old and new unanswered questions are waiting to be dug out from under old unquestioned answers about how becoming human unfolds. We will also address some popular and weighty, but deeply empty assertions about the circumstances and mechanisms of our beginnings and our ceaseless becoming. We will find fundamental questions from ‘the humanities’ unanswerable except from biology. Human developmental biology is a foundational discipline within the humanities. Readership: For intelligent people who want to understand the biology of the usual and some unusual ways of becoming human. 516pp 978-981-283-513-0(pbk)

June 2010 US$66

The Biophysical Reviews and Letters is an international peer-reviewed journal that publishes original research papers, review articles, brief communications and educational reviews in the field of experimental and theoretical Biophysics. It covers the whole area of Bionanosciences - including Biomolecules, Biocolloids (membranes, filaments, and minerals), Bioenergetics (molecular motors, growing filaments), Biofunctional, Bioinspired and Biomimetic Materials - as well as physical aspects of Structural and Molecular Cell Biology, Computational Biophysics, Bioinformatics, fundamental issues related to the Life Sciences, interdisciplinary Biological Physics utilizing methods from physics, chemistry, mathematics, computer sciences to resolve issues and challenges in biological science. The advance in biological physics will consequently exert impact on many related fields, including, soft matter, materials science, stochastic processes, econophysics, socioeconophysics, and biophysical economics.

£55

Indexed in Web of Science The Journal of Biological Systems is published quarterly. The goal of the Journal is to promote interdisciplinary approaches in Biology and in Medicine, and the study of biological situations with a variety of tools, including mathematical and general systems methods.

Biomedical Engineering: Applications, Basis and Communications http://www.worldscientific.com/bme

Personal Genomics and Personalized Medicine by Hamid Bolouri (California Institute of Technology, USA)

Indexed in Scopus

“Preserving the health benefits of genomics while minimizing the harms will be an important research goal. In that regard, Bolouri’s exploration is a timely addition.” Nature Readership: Practicing health professionals and researchers as well as senior undergraduates and graduate students in biomedical sciences. 272pp 978-1-84816-564-9 978-1-84816-565-6(pbk)

Feb 2010 US$68 US$45

Biomedical Engineering: Applications, Basis and Communications explores all facets of biomedical engineering, with emphasis on both the clinical and scientific aspects of the study. It covers the fields of bioelectronics, biomaterials, biomechanics, bioinformatics, nano-biological sciences and clinical engineering. The journal fulfils this aim by publishing regular research / clinical articles, short communications, technical notes and review papers. Papers from both basic research and clinical investigations will be considered.

View our Life Sciences e-catalogue at £56 £37

http://www.worldscientific.com/page/ ecatalogues/lifesci

Life Sciences 2018 Human Diversity

HUMAN BIOLOGY / BIOLOGICAL ANTHROPOLOGY / PRIMATOLOGY

Its Nature, Extent, Causes and Effects on People by Bernard Charles Lamb (Imperial College London, UK) “An interesting aspect of the book is its collection of personal accounts, first-person narratives by individuals who perceive themselves as different or who have been treated as being outside the norm. Biologists, social scientists, anthropologists, and general audiences who want a glimpse of how widely we humans differ, but also of how many ways we are similar, will enjoy this fascinating book.”

Human Amniotic Membrane Basic Science and Clinical Application edited by Nazly Hilmy (Centre for Research and Development of Isotopes and Radiation Technology, Indonesia), Norimah Yusof (University of Malaya, Malaysia) & Aziz Nather (National University Health System, Singapore)

CHOICE Connect

This book is a comprehensive guide for all tissue bank operators to screen, procure and process amniotic membrane for clinical application.

Readership: Students of medicine, biology, psychology and sociology, professionals working as diversity officers or in equalities, general readership.

Readership: Tissue bank operators in the Asia Pacific region.

448pp 978-981-4632-35-5 978-981-4632-36-2(ebook)

350pp 978-981-3226-34-0 978-981-3226-49-4(pbk)

Aug 2017 US$148

£63 £95

£130

Survival of the Fattest The Key to Human Brain Evolution by Stephen C Cunnane (Research Center on Aging, Universitéde Sherbrooke, Canada)

Biocommunication Sign-Mediated Interactions between Cells and Organisms edited by Richard Gordon (Gulf Specimen Aquarium & Marine Laboratory, USA & Wayne State University, USA), Joseph Seckbach (The Hebrew University of Jerusalem, Israel)

“Anyone interested in how humans evolved will find much of interest in this book ... the main thread of the argument seems so plausible that many readers will want to delve further by way of a number of the items listed in the bibliography.” Henry H Bauer Professor Emeritus of Chemistry & Science Studies, Dean Emeritus of Arts & Sciences Virginia Polytechnic Institute & State University

Split into two parts, this book first looks at the history, development and progress within the field of biocommunication. The second part presents reallife case studies and investigation into examples of biocommunication in the biological world. 700pp 978-1-78634-044-3 978-1-78634-045-0(ebook)

Dec 2015 US$76 US$114

Jan 2017 US$248 US$372

Readership: General public interested in origins of humans. 368pp 978-981-256-191-6 978-981-256-770-3(ebook)

£206 £309

Jul 2005 US$74 US$111

£61 £92

:: Bestseller Nano LIFE

GMO Sapiens

http://www.worldscientific.com/nl

The Life-Changing Science of Designer Babies by Paul Knoepfler (UC Davis)

“Knoepfler provides useful and accessible summaries of the public debates that surrounded the introduction of GMO foods, IVF, attempts at human cloning, and our current fascination with mitochondrial replacement. You should read both this book and Knoepfler’s blog. If you are not a blog person, I recommend reading this book as a good introduction both to the subject matter and to the methodology of a science blogger.”

Indexed in Web of Science

Cell Winner of the INDIEFAB 2015 Bronze Award for Science (Adult nonfiction). Readership: Undergraduate biology majors, graduate biology majors, non-experts interested in GMOs, biologists and teenagers interested in cloning and human genetic modification. 284pp 978-981-4667-00-5 978-981-4678-53-7(pbk) 978-981-4667-02-9(ebook)

Jan 2016 US$68 US$28 US$102

£56 £23 £84

Nano LIFE will effectively facilitate interactions and collaborations between the nano and medical research communities that are more focused on solving key problems based on emerging nanoscience and technologies. This journal is also addressed to researchers in a broad spectrum of materials, chemical, biological and medical sciences, and engineering. In addition, it summarizes the wealth of experimental results in both nanomaterials and biomedicine and introduces new aspects of nanoscience relevant to biological and medical applications. It also demonstrates new trends in the field and cultivates a new research community in both frontier research and higher education.

WORLD SCIENTIFIC

MICROBIOLOGY / VIROLOGY RESEARCH Pioneers in Microbiology The Human Side of Science by King-Thom Chung (University of Memphis, USA & National Sun Yat-sen University, Taiwan), Jong-Kang Liu (National Sun Yat-sen University, Taiwan) Pasteurization, penicillin, Koch’s postulates, and gene coding. These discoveries and inventions are vital yet commonplace in modern life, but were radical when first introduced to the public and academia. In this book, the life and times of leading pioneers in microbiology are discussed in vivid detail, focusing on the background of each discovery and the process in which they were developed — sometimes by accident or sheer providence.

Microbial Biotechnology Principles and Applications Third Edition edited by Yuan Kun Lee (National University of Singapore, Singapore) The rapidly expanding molecular biological techniques and approaches have significant impact on microbial biotechnology, hence the need for the addition of four new chapters in the third edition of this textbook — “Chapter 3: Application of ‘ Omics’ Technologies in Microbial Fermentation”, “Chapter 5: Microbial Genome Mining for Identifying Antimicrobial Targets”, “Chapter 21: Bacterial Biofilm: Molecular Characterization and Impacts on Water Management” and “Chapter 23: Microbial Biomining”. “Chapter 15: Transgenic Plants” has been completely revised while most of the other chapters have been thoroughly updated in this new edition. Readership: Undergraduates and teachers of tertiary institutions. Reference book for the industry (corporate planners, managers and applied research personnel).

Readership: Readers who are interested in the stories behind important discoveries in microbiology.

896pp 978-981-4366-81-6 978-981-4366-82-3(pbk)

650pp 978-981-3202-94-8 978-981-3200-36-4(pbk) 978-981-3200-37-1(ebook)

Pioneers of Microbiology and the Nobel Prize

Sep 2017 US$120 US$48 US$180

£100 £40 £150

Human Adenoviruses

This monograph describes the underlying principles of adenovirus molecular and structural biology, pathogenesis, antiviral measures and vector development. Much of the history of this virus and the many contributions made by its study are embedded in these discussions. Topics and questions that require further investigation are also considered.

by Ulf Lagerkvist (Gothenburg University, Sweden)

Readership: Microbiologists; medical researchers, undergraduates and graduate students in microbiology and the life sciences; general readers.

Readership: Graduate students and researchers interested in adenoviruses, gene therapists, and virologists. Feb 2017 US$148 US$222

£154 £78

“The book supplies superior details about the research and the social climate leading to the discoveries and provides good insight into the intellect and personalities that make extraordinary scientific discoveries. The rationale for awarding Nobel prizes in science is also thoroughly discussed ... For anybody interested in the history and process of science.” Choice

From Villains to Vectors by Jane Flint (Princeton University, USA), Glen R Nemerow (The Scripps Research Institute, USA)

416pp 978-981-3109-79-7 978-981-3109-80-3(ebook)

Apr 2013 US$185 US$94

188pp 978-981-238-233-7 978-981-238-234-4(pbk) 978-981-277-556-6(ebook)

£123 £185

Aug 2003 US$94 US$24 US$142

£78 £20 £118

NEUROBIOLOGY / NEUROANATOMY

Series in Structural Biology - Vol 7

Curiosity and Passion for Science and Art

Chronic Pain New Molecular Insights into Pain and Treatment by Min Zhuo (University of Toronto, Canada)

S-layer Proteins of Bacteria and Archaea by Uwe B Sleytr (University of Natural Resources and Life Sciences, Vienna, Austria) This book describes the accomplishments of a curious and imaginative scientist, and his endeavours to translate or even to extrapolate scientific insights into the world of art. Readership: Students and researchers in microbiology, nanobiotechnology, structural biology, supramolecular chemistry, and arts (biography, nature). 496pp 978-981-3141-81-0 978-981-3141-82-7(ebook)

Sep 2016 US$158 US$237

This book successfully explores cellular and molecular mechanisms of chronic pain based on recent basic neurobiological investigations. By focusing on major breakthroughs in basic neurosciences, it is believed to contain the promise for future new pain drug discovery.

£131 £196

Readership: Neuroscientists, medical students, pain researchers, nurses, doctors, and drug developers. 400pp 978-981-4324-52-6 978-981-4324-53-3(ebook)

Apr 2018 US$166 US$249

£138 £207

Life Sciences 2018

STEM CELLS RESEARCH Regeneration of Salivary Glands edited by Guy Carpenter (King’s College London, UK) This book examines the current state of salivary regeneration by understanding the normal processes of development, function and tissue repair. It also explores the experimental and clinical approaches to stem cell therapy, mostly for irradiation induced salivary gland damage. Readership: Postgraduates and researchers in the fields of regenerative medicine and stem cell research. 350pp 978-981-3143-43-2 978-981-3143-44-9(ebook)

May 2018 US$130 US$195

£108 £162

Engineering Stem Cells for Tissue Regeneration

Readership: Life science scientists, biomedical researchers, cell biologists, academics, postgraduate students and advanced undergraduate students in cell biology, biochemistry and genetics; surgeons; clinicians; biotechnology and pharmaceutical industry professionals.

£115 £173

Stem Cells

£41 £21 £61

Stem Cells An Insider’s Guide by Paul Knoepfler (UC Davis) “This is an opinionated but extremely knowledgeable introduction to the potentials and pitfalls of research in and applications of stem cells. The science is current, accessible, and well presented, but the best aspect of the book is its focus on ethical considerations associated with stem cell research. This is a fascinating book on important scientific, medical and consumer issues.” CHOICE Readership: Patients, scientists, biotech and big pharma people, students, investors, lawyers, employees of funding agencies such as the National Institute for Health (NIH) and the California stem cell agency, the US Food and Drug Administration (FDA), and researchers. Sep 2013 US$29 US$44

£24 £37

edited by Song Li (University of California, Berkeley, USA), Nicolas L’Heureux (Cytograft Tissue Engineering, USA) & Jennifer Elisseeff (Johns Hopkins University, USA)

Readership: Interested lay readers, researchers and medical doctors. Oct 2016 US$35 US$18 US$53

Dec 2015 US$49 US$24.99 US$74

Stem Cell and Tissue Engineering

The book constructs step by step the required basic biology knowledge in order for the reader to understand all the different aspects of stem cells. At the same time that it is thorough in its stem cells-based content, and will keep the reader engaged with its narrative.

108pp 978-981-3100-18-3 978-981-3100-19-0(pbk) 978-981-3100-20-6(ebook)

Readership: General readers, caregivers of someone with chronic disease, patient advocates, students in biomedical science, policy makers in government, stem cell researchers.

368pp 978-981-4508-80-3(pbk) 978-981-4508-81-0(ebook)

Promise and Reality by Lygia V Pereira (University of São Paulo, Brazil)

“Impassioned advocacy for stem cell research … recommended for anyone interested in the California Institute for Regenerative Medicine, its origins, and its accomplishments so far …” Dr James Till co-recipient (with Ernest McCulloch) of Lasker Award Toronto, Canada

:: Bestseller

This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs, including cardiovascular, musculoskeletal, neurological and skin tissues. The technology platforms for studying and engineering stem cells, such as hydrogel and biomaterials development, microfluidics system and microscale patterning, are also illustrated. Regulatory challenges and quality control for clinical translation are also detailed.

Jan 2018 US$138 US$207

How Ordinary People Can Fight Back against the Crushing Burden of Chronic Disease — with a Posthumous Foreword by Christopher Reeve by Don C. Reed (Americans for Cures Foundation, USA)

432pp 978-981-4644-01-3 978-981-4618-27-4(pbk) 978-981-4618-28-1(ebook)

edited by Song Li (UC Los Angeles), Nicolas L’Heureux (National Institute for Health and Medical Research (INSERM), France), Jennifer Elisseeff (Johns Hopkins University, USA) & Ngan F Huang (Stanford University, USA)

350pp 978-981-3147-74-4 978-981-3147-75-1(ebook)

Stem Cell Battles: Proposition 71 and Beyond

£29 £15 £44

View our Bestseller Life Sciences page at : http://www.worldscientific.com/page/bestsellers#lifesci

This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves as a valuable reference book for researchers and students. Readership: Life science scientists, biomedical researchers, cell biologists, academics, postgraduate students and advanced undergraduate students in cell biology, biochemistry and genetics, surgeons, clinicians, biotechnology and pharmaceutical industry professionals. 472pp 978-981-4317-05-4 978-981-4317-06-1(ebook)

Mar 2011 US$154 US$231

£128 £192

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The FIRST Journal to Publish Original Research Articles in ALL Fields of Mechanics in Medicine and Biology This journal has as its objective the publication and dissemination of original research (even for â&#x20AC;&#x153;revolutionary concepts that contrast with existing theoriesâ&#x20AC;? & â&#x20AC;&#x153;hypothesisâ&#x20AC;?) in all fields of engineering-mechanics that includes mechanisms, processes, bio-sensors and bio-devices in medicine, biology and healthcare. The journal publishes original papers in English which contribute to an understanding of biomedical engineering and science at a nano- to macro-scale or an improvement of the methods and techniques of medical, biological and clinical treatment by the application of advanced high technology.

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Shire Championing the Cause for Patients with Rare Diseases p. 12

ASEAN+ Rare Disease Network: Unifying Voices of Patients p. 14

Rainbow Across Borders p. 17

Most Read Articles Recent advances in nonbiofouling PDMS surface modification strategies applicable to microfluidic technology Aslihan Gokaltun, Martin L. Yarmush, Ayse Asatekin, O. Berk Usta DOI: 10.1142/S2339547817300013

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Modular pumps as programmable hydraulic batteries for microfluidic devices Brian M. Cummins, Rukesh Chinthapatla, Balaji Lenin, Frances S. Ligler, Glenn M. Walker DOI: 10.1142/S2339547817200011

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Stain-less staining for computed histopathology David Mayerich, Michael J. Walsh, Andre Kadjacsy-Balla, Partha S. Ray, Stephen M. Hewitt, Rohit Bhargava DOI: 10.1142/S2339547815200010

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Cell-free vascular grafts: Recent developments and clinical potential Sindhu Row, Ana Santandreu, Daniel D. Swartz, Stelios T. Andreadis DOI: 10.1142/S2339547817400015

Established in 1997, Asia Pacific Biotech News (APBN) is the first monthly publication on pharmaceuticals, biotechnology, agriculture, healthcare and nutrition in the Asia Pacific region. It is read by research scientists, academia, healthcare professionals and investors worldwide.

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INNOVATION provides the bridge that links the esoteric technicalities of R&D to everydayâ&#x20AC;&#x2122;s life. It presents the significance of current work being undertaken by researchers in a style accessible to the educated layperson. The magazine is jointly published by Nanyang Technological University, National University of Singapore and World Scientific Publishing.

Life Sciences 2018

Frontiers in Nanobiomedical Research - Vol 9

Frontiers in Nanobiomedical Research - Vol 5

The World Scientific Encyclopedia of Nanomedicine and Bioengineering II

The World Scientific Encyclopedia of Nanomedicine and Bioengineering I

Bioimplants, Regenerative Medicine, and Nano-Cancer Diagnosis and Phototherapy (A 3-Volume Set) edited by Maoquan Chu (Tongji University, China), Jiang Chang (Chinese Academy of Sciences, China) Editor-in-chief: Donglu Shi (University of Cincinnati, USA)

Nanotechnology for Translational Medicine: Tissue Engineering, Biological Sensing, Medical Imaging, and Therapeutics (A 4-Volume Set) edited by Yu Cheng (East Hospital, Tongji University School of Medicine, China), Jia Huang (School of Materials Science and Engineering Tongji University, China), Yarong Liu (University of Southern California, USA), Pin Wang (University of Southern California, USA) & Bingbo Zhang (Tongji University School of Medicine, China) Editor-in-chief: Donglu Shi (East Hospital, Tongji University School of Medicine, China & University of Cincinnati, USA)

This two-part multivolume set provides a comprehensive overview of current achievements in biomedical applications of nanotechnology, including stem cell based regenerative medicine, medical imaging, cell targeting, drug delivery, and photothermal/photodynamic cancer therapy. New approaches in early cancer diagnosis and treatment are introduced with extensive experimental results. In particular, some novel materials have been synthesized with new properties that are most effective in cancer therapy. Some of the key issues are also addressed with these recent discoveries such as bio safety and bio degradability, that are essential in the success of nano medicine. An important aspect of this book set is the introduction of nanotechnology to the medical communities that are searching for new treatments of cancer. It may also break the barriers between the physical and medical sciences so that more MDs will be able to appreciate the new discoveries and establishments in medical diagnosis and therapy that will allow the effective handling of major clinical issues.. Readership: University students and researchers from diversified backgrounds such as physics, materials science, engineering, and chemistry. The World Scientific Encyclopedia of Nanomedicine and Bioengineering II 900pp (Set II) Aug 2017 US$880 £730 978-981-4667-58-6(Set) US$780 £647 978-981-4667-59-3(Set)(ebook) US$1320 £1095

The World Scientific Encyclopedia of Nanomedicine and Bioengineering I 1156pp (Set I) Oct 2016 978-981-4667-65-4(Set) US$1100 £913 978-981-4667-66-1(Set)(ebook) US$1650 £1370

Introductory offer till Oct 31, 2017

The World Scientific Encyclopedia of Nanomedicine and Bioengineering II

VOLUME 1: GRAPHENE QUANTUM DOTS Chapter 1 Properties and Synthesis Strategies of Graphene Quantum Dots Chapter 2 Synthesis and Amino-Functionalization of the Graphene Quantum Dots Chapter 3 Plasmons in Graphene Quantum Dots Chapter 4 Application of Graphene Quantum Dots in Medical and Pharmaceutical Analyses Chapter 5 Graphene Quantum Dots for Food Analysis Chapter 6 Fluorescent Graphene Quantum Dots for Bioimaging Chapter 7 Graphene Quantum Dots for Drug Delivery Chapter 8 Toxicity of Graphene Quantum Dots VOLUME 2: ADVANCED NANOMATERIALS FOR BIOIMAGING Chapter 1 Radiolabeled Nanoparticles for In Vivo Tumor PET Imaging Chapter 2 Measurement and Imaging of Raman Spectroscopy with Nanoparticles Chapter 3 Preparation of Magnetic Iron Oxide Polymerized Nanoparticles and Their Applications in Magnetic Resonance Imaging Chapter 4 Gold Nanoparticles: A Versatile Platform for Cancer Diagnosis, Imaging and Therapy Chapter 5 Graphene Quantum Dots for Bioimaging and Cancer Therapy Chapter 6 Magnetic Nanoparticles for Cancer Therapy through Magnetic Field-Mediated Mechanical Force Stimulation Chapter 7 Tumor Extracellular Acidity-Sensitive Polymeric Nanocarriers for

Drug Delivery and Cancer Therapy Chapter 8 Polysaccharides-Based Polymeric Nanoparticles for VOLUME 3: DESIGN OF BIOACTIVE MATERIALS Chapter 1 Calcium Orthophosphate Coatings and Other Deposits Chapter 2 Biomimetic Synthesis of Nanostructured Calcium Phosphates Chapter 3 Biological Effect of Ions in Calcium Phosphates on Bone Regeneration Chapter 4 Bioactive Glasses Chapter 5 Biological Coatings for Implant Surface Modification Chapter 6 Biomaterials and Biotechnologies for Treatment of Osteoporosis and Osteoporotic Injuries Chapter 7 Design of Silicate-Based Bioactive Materials for Bone Tissue Repair and Reconstruction Chapter 8 Design of Bioactive Materials for Bone Repair and Regeneration Chapter 9 Potential Applications of Cellulose and Its Composites in Bone Repairment and Regeneration Chapter 10 Bisphosphonate-Immobilized Biomaterials for Bone Engineering and Curing of Bone Diseases Chapter 11 Advanced Analyses for Characterizing Bone Repair and Osseointegration Drug Delivery and Tumor Therapy Chapter 9 Multifunctional Nanocomplexes for Gene Transfer and Gene Therapy Chapter 10 Liposomal Delivery System for Small Molecular Therapeutic Drugs

WORLD SCIENTIFIC

Title Index

R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R

Tick the titles and email to mkt@wspc.com to recommend to your librarian.

Algal and Cyanobacteria Symbioses ...................................................................................10 Analysis of Biological Systems ............................................................................................7 Biocatalysis ........................................................................................................................9 Biocommunication .............................................................................................................16 Biocomputing 2017 ............................................................................................................7 Bioengineering in Wound Healing ......................................................................................6 Bioinformatics ....................................................................................................................7 Bio-Inspired Surfaces and Applications ...............................................................................6 Biological Shape Analysis ...................................................................................................10 Biomedical Engineering: Applications, Basis and Communications (BME)...........................15 Biophysics and Biochemistry of Protein Aggregation ...........................................................5 Biophysics of Consciousness ...............................................................................................13 Biotechnology and Medical Science ...................................................................................9 Chronic Pain .......................................................................................................................17 Compendium of In Vivo Monitoring in Real-Time Molecular Neuroscience ........................4 Computational Chemotaxis Models for NeurodegenAerative Disease .................................8 Computational Structural Biology .......................................................................................7 Computational Systems Biology of Synaptic Plasticity .........................................................7 Cultured Meat.....................................................................................................................9 Cures vs Profits ...................................................................................................................13 Curiosity and Passion for Science and Art ...........................................................................17 DNA Nanotechnology for Bioanalysis.................................................................................8 Drug Delivery Systems ........................................................................................................8 Electrically Active Materials for Medical Devices ................................................................5 Embryogenesis Explained....................................................................................................12 Emperor of Enzymes ...........................................................................................................13 Engineering Microbial Metabolism for Chemical Synthesis ................................................4 Engineering Stem Cells for Tissue Regeneration ...................................................................18 Epigenetics in Human Reproduction and Development ......................................................14 Fibroblast Growth Factors: Biology and Clinical Application...............................................11 Fusion Genes and Cancer ...................................................................................................10 GMO Sapiens .....................................................................................................................16 Handbook of Forensic Genetics ..........................................................................................14 Handbook of Photodynamic Therapy ..................................................................................10 How New Humans Are Made .............................................................................................15 How to Read and Critique a Scientific Research Article ......................................................13 Human Adenoviruses..........................................................................................................17 Human Amniotic Membrane ..............................................................................................16 Human Diversity ................................................................................................................16 Human DNA Polymerases ..................................................................................................4 Information Theory and Evolution .......................................................................................15 Injectable Hydrogels for Regenerative Engineering..............................................................6 Luminous Pursuit ................................................................................................................5 Matrix Metalloproteinases in Health and Disease ...............................................................11 Meaning of Life and the Universe .......................................................................................5 Metallomics ........................................................................................................................5 Microbial Biotechnology ....................................................................................................17 Molecular Bioelectronics ....................................................................................................8

R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R

Molecular Frontiers Journal (MFJ) ......................................................................................22 Multiscale Technologies for Cryomedicine ..........................................................................6 Myths and Verities in Protein Folding Theories ....................................................................13 Nanobioceramics for Healthcare Applications ....................................................................8 Nanomaterials for Tumor Targeting Theranostics ..................................................................8 Nobel Prizes and Nature’s Surprises ....................................................................................13 Nobel Prizes and Notable Discoveries ................................................................................12 Periodic Tables Unifying Living Organisms at the Molecular Level ......................................4 Personal Genomics and Personalized Medicine ..................................................................15 Perspectives in Micro- and Nanotechnology for Biomedical Applications ...........................6 Pioneers in Microbiology ....................................................................................................17 Pioneers of Microbiology and the Nobel Prize ....................................................................17 Quantitative Genetics and Its Connections with Big Data and Sequenced Genomes ...........14 Regeneration of Salivary Glands .........................................................................................18 Rho GTPases ......................................................................................................................11 Self and the Phenomenon of Life ........................................................................................12 Semiconductor Quantum Dots and Rods for In Vivo Imaging and Cancer Phototherapy .....6 Stem Cell and Tissue Engineering ........................................................................................18 Stem Cell Battles: Proposition 71 and Beyond ....................................................................18 Stem Cells (An Insider’s Guide) ...........................................................................................18 Stem Cells and Tissue Engineering.......................................................................................18 Structure and Action of Molecular Chaperones ...................................................................12 Structure and Mechanism in Protein Science ......................................................................4 Survival of the Fattest ..........................................................................................................16 Synthetic Biology and Bioweapons .....................................................................................9 Textbook of Structural Biology ............................................................................................12 The Base Excision Repair Pathway ......................................................................................11 The Cell Language Theory ..................................................................................................11 The Ethics and Biosecurity Toolkit for Scientists...................................................................9 The Life of Professor Robert Hugh Pritchard ........................................................................14 The Story of Genetics, Development and Evolution ............................................................14 The Struggles and Dreams of Robert Langer ........................................................................13 The Training of Cancer Researchers.....................................................................................10 The World Scientific Encyclopedia of Nanomedicine and Bioengineering I.........................20 The World Scientific Encyclopedia of Nanomedicine and Bioengineering II........................20 Tissue Engineering and Nanotheranostics ...........................................................................4 Unravelling Complexities in Genetics and Genomics .........................................................14 Vascular Smooth Muscle.....................................................................................................11

R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R

Ng Eddie Yin-kwee............................... 6 Ng Kian Bee ...................................... 12 Nicolini Claudio .................................. 8 Nissen Poul........................................ 12 Norrby Erling ................................ 12,13 Padmavathi Ganesan.......................... 10 Pandey Ravindra K ............................. 10 Peitsch Manuel C ................................. 7 Pereira Lygia V ................................... 18 Poznanski Roman R ........................... 13 Reed Don C ....................................... 18 Ritchie Marylyn D ............................... 7 Rose Nikolas D .................................... 9 Roy Nand Kishor ............................... 10 Russo Jose.......................................... 10 Saunders Peter T .................................. 5 Schiesser William E.............................. 8 Schwede Torsten .................................. 7 Seckbach Joseph ........................... 10,16 Shi Donglu ......................................... 4 Shi Donglu ........................................ 20 Shimomura Osamu .............................. 5 Simons Michael ................................ 11 Sleytr Uwe B...................................... 17 Slingsby Christine ............................. 12 Smith Moyra ..................................... 14 Spadari Silvio ...................................... 4 Stroeve Pieter ...................................... 8 Sture Judi ............................................ 9 Syed Tofail .......................................... 5 Taketo-hosotani Teruko ..................... 14 Tammi Martti tapani ............................ 7 Tan Mingqian ...................................... 8 Thian Eng San ..................................... 8 Tuszynski Jack A ............................... 13 Villani Giuseppe ................................. 4 Wang Liqian ....................................... 8 Welin Stellan ...................................... 9 Wickner Sue ..................................... 12 Wilson Geroge S ................................. 4 Wilson Iii David M ........................... 11 Wu Aiguo ........................................... 8 Xu Chenjie .......................................... 6 Yan Yajun ............................................ 4

Author Index R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R

Agard David ...................................... 12 Aizawa Mamoru .................................. 8 Altman Russ B ..................................... 7 Amorim Antonio ................................ 14 Arrabito Giuseppe Domenico .............. 8 Ash Miriam-rose ................................ 12 Avery John Scales .............................. 15 Bauer Joanna ....................................... 5 Ben-naim Arieh.................................. 13 Bischof John C ..................................... 6 Blangy Anne ...................................... 11 Boklage Charles Edward .................... 15 Bolouri Hamid ................................... 15 Brinckerhoff Constance E ................... 11 Brinegar John H ................................... 5 Budowle Bruce .................................. 14 Carpenter Guy ................................... 18 Chan Juliana M .................................... 6 Chang Jiang ....................................... 20 Cheng Yu ........................................... 20 Chu Maoquan................................. 6,20 Chung King-thom .............................. 17 Cunnane Stephan Cosgrave ............... 16 Dougherty Thomas J........................... 10 Duker A Keith ...................................... 7 Elisseeff Jennifer ................................. 18 Feinberg Todd E ................................ 13 Fersht Alan R ....................................... 4 Flint S Jane......................................... 17 Fort Philippe ...................................... 11 Friedberg Errol C ................................ 13 Gierasch Lila M ................................. 12 Golberg Alexander............................... 6 Gordon Natalie K .............................. 12 Gordon Richard ............................ 12,16 Grube Martin ..................................... 10 Grunwald Peter.................................... 9 Haagsman Henk P ............................... 9 Hai Chi-ming ..................................... 11 He Shawn Xiaoming ............................ 6 He Yao ................................................. 7 Hilmy Nazly ...................................... 16 Ho Mae-wan ....................................... 5 Horwich Arthur L ............................... 12

R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R R

Huang Jia........................................ 8,20 Huang Ngan ...................................... 18 Hubscher Ulrich .................................. 4 Hunter Lawrence ................................. 7 Jefferson Catherine............................... 9 Jekely Gaspar..................................... 14 Ji Sungchul ........................................ 11 Kessel David ...................................... 10 Kjeldgaard Morten ............................. 12 Klein Teri E........................................... 7 Knoepfler paul .............................. 16,18 Kulasiri Don ........................................ 7 Kunnumakkara Ajaikumar B .............. 10 Lagerkvist Ulf..................................... 17 Lamb Bernard Charles ....................... 16 Langer Robert .................................... 13 Lee Yuan Kun ..................................... 17 Lentzos Filippa .................................... 9 Lestrel Pete E...................................... 10 L‘heureux Nicolas.............................. 18 Li Song .............................................. 18 Liljas Anders ...................................... 12 Liljas lars ........................................... 12 Lim Ramon ........................................ 12 Lima-de-faria Antonio .......................... 4 Lindblom Goran ................................ 12 Liu Jong-kang..................................... 17 Liu Qing .............................................. 4 Liu Yarong .......................................... 20 Low Llyod Wai Yee .............................. 7 Lup Yuehao .......................................... 6 Lyons-weiler James ............................ 13 Maga Giovanni .................................... 4 Mahmoudi Morteza ............................. 8 Maret Wolfgang ................................ 5,7 Marris Claire ........................................ 9 Michael Adrian C................................. 4 Mode Charles J .................................. 14 Muggia Lucia ..................................... 10 Murray Tiffany A .................................. 7 Nair Lakshmi S .................................... 6 Nather Abdul Aziz ............................. 16 Naumva Anna K ................................ 14 Nemerow Glen R............................... 17

R R R R R R R R R R

Yarmush Martin L ................................ 6 Yeong Foong May ............................. 13 Yuan Jian-min ..................................... 5 Zaritsky Arieh ................................... 14 Zhang Bingbo ................................... 20 Zhang Jiaxing ...................................... 9 Zhang Shuguang ............................... 13 Zhang Yong ......................................... 9 Zhou Huan-xiang ............................... 5 Zhuo Min ......................................... 17

Life Sciences 2018

Molecular Frontiers Journal Open Access Journal Newly launched in June 2017

http://www.worldscientific.com/mfj Recognizing the need to identify and advance the important messages of science, a number of individuals gathered in Sweden to form what became known as the Molecular Frontiers Foundation. Since 2006, this organization operates as a non-profit, hosted by the Royal Swedish Academy of Sciences. Its Scientific Advisory Board, including many Nobel Prize laureates, represents expertise from a wide range of scientific disciplines. Over the past ten years the MFF has been creating symposia that serve to identify and consider scientific initiatives of global import. This sharing of discovery, serves to increase accessibility to, as well as foster the understanding of new scientific developments, while serving to inspire audiences of all ages around the world. The mission of MFF is to raise the appreciation and access to molecular science, hoping to cultivate interest among the general public with a specific focus on stimulating an interest in the sciences in young people. The organization also serves to connect key researchers from around the world on matters of notable scientific significance.

Editor-in-Chief P f Professor Bengt B t Nordén N (Founder & Chair, Molecular Frontiers Foundation, Chalmers University of Technology, Sweden)

Managing Editor D Lorie Dr. L i K Karnath th (Chair Strategic Advisory Board, Molecular Frontiers Foundation, Jason Learning, Germany)

Inaugural issue Advances in Chemistry and Their Implications for Studying and Treating Brain Disease Robert Langer

Making Materials That Hate Water to Love Water: The Transformative Power of Chemistry Richard N. Zare Seeking Habitable Environments in Our Solar System: Curiosity on Mars Laurie Leshin, the Mars Science Laboratory Science Team The Universe, a Personal View on Exploring the Boundaries, or: The Science of the Extremes Gerard ’t Hooft Molecular Inference of Wisdom G. Terry Sharrer Dynamics of Molecular Processes and the Sustainable Development of Humanity Yuan Tseh Lee Nanoscience — Potential and Threats Paul Alivisatos

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Featured Articles Evaluating feature-selection stability in next-generation proteomics Wilson Wen Bin Goh, Limsoon Wong Journal of Bioinformatics and Computational Biology Vol. 14, No. 05, 2016 DOI: 10.1142/S0219720016500293

Accurate refinement of docked protein complexes using evolutionary information and deep learning Bahar Akbal-Delibas, Roshanak Farhoodi, Marc Pomplun, Nurit Haspel Journal of Bioinformatics and Computational Biology Vol. 14, No. 03, 2016 DOI: 10.1142/S0219720016420026 A hybrid model of cell cycle in mammals Jonathan Behaegel, Jean-Paul Comet, Gilles Bernot, Emilien Cornillon, Franck Delaunay Journal of Bioinformatics and Computational Biology Vol. 14, No. 01, 2016 DOI: 10.1142/S0219720016400011

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