Anti aging supplement

Anti-Aging Research People 50 and older have a lot to look forward to, according to Juvenescence’s Greg Bailey—mainly that we won’t be aging as fast or poorly as our parents. “Science fiction has become science,” said the UK-based anti-aging biotech’s CEO about the company’s completing its $100 million Series B round of financing last week. “I think the world is going to be shocked,” he said in an interview. In total, Juvenescence has now raised $165 million in just 18 months to fund longevity projects with the lofty goal of extending human lifespans to 150 years.

Bailey said the money will allow the company “to progress all of our products.” And there’s quite a list of potential therapies. “We have 12 programs based on hard, rigorous science, to try to modify aging. From stem cell research to senolytics to modifying or preventing Alzheimer’s and Parkinson’s diseases,” he said.

It’s no secret that anti-aging is big business. According to Endpoints News, “Bank of America has forecast the market will balloon to $610 billion by 2025, from an estimated $110 billion currently.”

“I think there’s a huge amount of skepticism. There’s an enormous number of charlatans…I understand why they would be thinking you know, is this real?” Bailey told Endpoints. “Walk into your local drugstore, you’re going to see about 50 products that claim to be anti-aging, and I can assure you that none of them are.”

Bailey said creams that claim everything and do nothing and vitamins that basically give users “expensive urine” are the reason for that skepticism.

And investors are not as quick to step up as he would like. Bailey told Endpoints: “We’re dramatically being underserved…it’s not getting the exposure that tech gets, considering the size of the market.” He said he believes there is “a disconnect” on how investors and institutions are viewing anti-aging technology. “I don’t think they quite grasp how fast this is going to happen, and how big it’s going to be.”

And according to Market Watch, Juvenescence has a fair share of competition, including: Life Biosciences, the Boston-based company founded in 2016 by scientists David Sinclair and Tristan Edwards to invest in the eight pathways of age-related decline. “In January, Life Biosciences raised $50 million in a Series B financing – twice its original target - to grow its portfolio of ‘daughter companies’ which carry out their own research and development programs,” Market Watch reported.

Investors are also closely watching Rejuvenate Bio—the start-up, co-founded by Harvard Medical School professor George Church, Market Watch reports. The company is testing 60 different age-reversing gene therapies. “The company, which carried out initial tests on beagles, claims it can reverse aging in animals by adding new DNA instructions to their bodies,” Market Watch reported. “It has announced plans to launch a trial later this year to combat mitral valve disease, a condition which is common in the Cavalier King Charles Spaniel breed and directly caused by ageing.”

Among the Juvenescence-backed programs is one from AgeX Therapeutics. The company focuses on targeting human aging with new therapies and medicines. Currently AgeX is studying stem cells for tissue and organ rejuvenation. “Stem cells are programmed to die.

The cells AgeX are creating are stem cells we could give to you, and they could bind to your heart and fix your heart,” he said. “They are creating cell lines from a single cell of tissue from IVF clinics. These are all living embryonic cells.”

Bailey said with the company’s PureStem® cell-based technologies, it has the ability to generate pluripotent or self-renewing stem cell-derived young cells of any type to potentially cure a range of age-related degenerative diseases. For example, the company hopes to one day be able to inject the cells locally into the damaged portion of an individual’s heart or spinal cord. “They would be one-day old cells, not 70-year-old cells,” Bailey said.

And, according to its website, with its induced Tissue Regeneration (iTR™) longevity platform, AgeX hopes to “unlock cellular immortality and regenerative capacity to reverse age-related changes in the body.”

Healthier, longer lifespans with new tissues and organs will be a reality sooner than anyone thinks, Bailey said. “We are just learning so much so fast,” Bailey said. “It’s happening now.

It’s not in the future, and it will happen faster than people think. The potential to regrow a lung or a limb is extraordinary.”

Juvenescence-backed biotechnology company, LyGenesis, Inc., hopes to enter human trials next year on a therapy that could potentially give patients with end stage liver disease hope for new livers without having to wait on donated organs. The technology uses lymph nodes as bioreactors to regrow functioning organs within a patient's own body. “In the U.S., we don’t have enough livers to do transplants—which are a $700,000 procedure,” Bailey said. The company is working on injecting cadaver cells into lymph nodes to grow secondary livers, he said.

Fueled by research from Eric Lagasse, PharmD, PhD, associate professor in the Department of Pathology at the University of Pittsburgh (UPIT) and LyGenesis' Chief Scientific Officer, the research found that a variety of different cells types and tissues, including the liver, could engraft and actually grow within lymph nodes.

"Remarkably, we were able to get these transplanted cells to organize, proliferate and vascularize into functioning ectopic organs, which rescued animals from otherwise fatal cases of organ failure," Lagasse said in a statement. The research is funded in part by the National Institutes of Health (NIH) and conducted at UPIT’s McGowan Institute for Regenerative Medicine.

Michael Hufford, PhD, Chief Executive Officer of LyGenesis, said the technology could address the problem of the imbalance between organ supply and demand. Instead of one donated organ treating just one patient, one donated organ could serve as the seed to treat

dozens of patients simultaneously, he said. And procedures using Lygenesis' technology would not require major transplantation surgery, Hufford said in a statement, “but would instead use a minimally invasive outpatient endoscopy, decreasing costs while enabling patients considered too sick or having too many comorbidities to qualify for traditional organ transplantation to receive treatment."

“Wouldn’t it be amazing if you were a diabetic and you could create a new pancreas from your own lymph nodes?” Bailey asked. “The things happening are going to be extraordinary.”

There is almost no limit to what tissue regeneration therapies could do to improve and lengthen the human lifespan, Bailey said. “If a child cuts off the tip of his finger and they are under the age of seven, it can regrow. We have that capability in us, but we lose it at a certain age. We are now learning how to turn that back on in adults. It is possible to regrow a kidney or a limb. And you know, I’m mindful that if you live to 150, people don’t want to be all wrinkled and in a wheelchair. So what we want to be able to do is regenerate tissues,” Bailey said.

Aside from Juvenescence, he noted the 2017 study on middle-aged fruit flies wherein UCLA biologists developed an intervention that serves as a cellular time machine—substantially improving the animals’ health while significantly slowing their aging. The ongoing mitochondria-focused research aims to lead to therapeutics that could delay the onset of Alzheimer’s, Parkinson’s and cardiovascular disease as well as cancer, stroke and other age-related human diseases.

Then there are the joint ventures with companies such as Alex Zhavoronkov’s AI shop at Insilico Medicine and the Buck Institute, where the biotechs and researchers at each company have combined their knowledge to form partnerships with Juvenescence to develop small molecules as new targets to attempt to extend life spans.

Juvenescence is backed by British International biotech investor, Jim Mellon, who launched the company in 2017 and then wrote a 400-page guide to investing in the field of longevity.

The study of aging and longevity is growing in popularity as well as fueling hope that humans could actually live into their 150s. “It is a popular vision. Inspired by Mellon, venture capitalist Sergey Young—who is in charge of all things longevity at the non-profit XPRIZE and VC fund BOLD Capital Partners—unveiled a $100 million fund with the same goal in February,” Endpoints’ Natalie Grover reported last week. “Google-owned stealthy biotech Calico is after the same prize — and has partnered with AbbVie $ABBV.” Nanalyze, a website that offers information for investors on emerging technologies, recently published a list of the top 10 companies working to increase longevity. Insilico Medicine and AgeX are among them.

Bailey said Juvenescence expects to have at least four anti-aging products on the market within seven years.

He likened the outcome of anti-aging research to the study of flight. “In 1903, two brothers flew a glorified kite for 14 seconds, the Kitty Hawk. Fifteen years later they were flying planes in WWI, and 35 years later, the Germans had invented the jet. Sixty-five years later

we landed a man on the moon. For robotics and for aging, divide that number by 10. That's how fast this is going to happen.�

Supermodel Lauren Hutton may have just landed a plum beauty contract at the age of 75, but when it comes to maintaining her stunning looks, the fashion star does not credit a serum or face cream, but rather something that cannot be purchased from a drugstore counter: sex.

The supermodel, who was recently named as the first ever celebrity face of anti-aging brand StriVectin, confessed that, while she does use the brand's products, her go-to beauty staples are 'a good man' and 'not giving up sex'.

'As we age, women can be good-looking and vibrant in every way,' Lauren told People of her beauty philosophy, before advising her fellow ladies to 'certainly not give up sex because that's just silly'.

Scroll down for video Stay young! Supermodel Lauren Hutton, 75, has confessed that the secrets behind her good looks are a 'good man' and 'never giving up sex' Thrilled: The septuagenarian was recently named as the face of anti-aging brand StriVectin, but confesses that her long-time beauty secrets don't include any specific skincare products Lauren remained tight-lipped about any 'good men' in her life however, although she did admit that she currently has a 'main squeeze' in her life.

The fashion superstar has kept her romantic life incredibly private for the past few decades, after going through a very public controversy surrounding her relationship with her former manager Robert Williamson, whom she began dating in 1967.

After Robert, who was known to many as Bob, passed away in 1997, Lauren revealed that he had squandered $30 million worth of her earnings during their 27-year relationship. She also confessed that he had been unfaithful on several occasions, and that he refused to have a child with her.

However, Lauren still credits him with 'saving her life about five times' while they were together, and notes that he served as something of a protector and father figure to her at times.

After that, Lauren was in a relationship with director Luca Babini until 1997, and she then went on to date Sex Pistols manager Malcolm McLaren, however she has since remained incredibly tight-lipped about her other romances, explaining to Harper's Bazaar in that she 'doesn't want anyone to ever know who she's with ever'.

'It's an infection that comes in [the relationship],' she said of her celebrity status, before adding that 'Bob certainly didn't want to be Mr. Hutton'.

Although sex and the company of a handsome gentleman might be her top beauty tips, the supermodel does have others to offer, crediting 'laughing, reading, and being in nature' with

helping her to stay looking and feeling young - as well as one very simple, natural product: coconut oil.

'I used to use a lot of coconut oil,' she shared. 'I put that in my hair and all over my body.

And then don’t use too much makeup.'

Since she started working with StriVectin, that beauty philosophy appears to have changed somewhat however, with the supermodel confessing that she has been trying and loving several of the items in the brand's range.

The style legend appears in a striking new campaign for anti-aging beauty brand StriVectin, having been named as the company's first ever celebrity ambassador - an achievement that she described as being one of the 'proudest' moments in her life.

'I said coming back [to fashion] at 46 or 47 was the thing I'm proudest of, but it makes me awful proud to come back at 75,' she said at an event to celebrate her partnership with the high-end brand.

Love life: Lauren stayed tight-lipped about her current flame, however she's previously been in relationships with director Luca Babini (left) and Sex Pistols manager Malcolm McLaren (right) Striking: Lauren, pictured in 1974, was one of the world's most successful supermodels during that era, alongside the likes of Twiggy and Jean Shrimpton New ideas: At an event to celebrate the new partnership, Lauren, pictured in 1975, said she is so proud to have traveled around the world and seen so many beautiful women She then recalled of her past comeback: 'When I was 46 [in 1987], I started calling all the editors around the western world that I knew and didn't know and said, "Women have gone into everything... but we need to go into our actual image. '"And you don't have to use me [for a campaign or a shoot] but you have to use someone my age. Because who are men really going to sleep with?"'

Lauren also praised the skincare brand for being 'hip enough to show the world that we can be beautiful at all ages', while thanking StriVectin for giving her the chance to work alongside her goddaughter Nina Clemente - a professional chef who appears with the supermodel in the stills and video for the new campaign.

In one photo, the two women are seen cuddling one another, with Nina, 38, holding her hand up to Lauren's face as they both beam at the camera.

Meanwhile in the video, the pair are joined by a fluffy dog, and are seen laughing with one another while waving the pup's paws in the direction of the cameraman.

However for Lauren, Nina's appearance in the campaign has far more significance than providing a personal memory for the two of them. Instead, she believes it helps to show people everywhere that beauty is not limited to just one age group, but rather exists in everyone no matter how old or young they are.

In a brand statement, StriVectin explained that it wanted its new campaign - along with the message, 'Hold on to your collagen. At every age' - to 'celebrate multi-generational beauty and the notion that part of looking and feeling your best is holding on to what matters most, who you are and what you love'.

Speaking at a New York City launch event earlier this month, when it was revealed that Lauren will also be helping to re-launch StriVectin's first ever product, SD Advanced Plus Intensive Moisturizing Concentrate for Wrinkles & Stretch Marks, the supermodel said how grateful she was to have experienced ageless beauty around the world.

Revealing how 'proud' she is to have traveled as much as she has done, Lauren said that 'one of the first things you see is that beauty is everywhere'.

'And great women are everywhere,' she continued. 'Every size, every shape, every height...

I saw women I wanted to rush out and eat 20 cannellonis with!

Believer: Lauren praised the brand's products and said that, although she has not been using them for too long, she has noticed a difference in her skin Partners: Lauren was joined on her campaign shoot by her 38-year-old goddaughter Nina Clemente, who is a professional chef 'We are all lucky that we are living in a time finally where we are being faced a little better.' .

'I guess the most important thing to say about maintaining a vitality and a brain and an alertness and wanting to love life is, especially in these scary times, [holding] on to what you loved when you were a kid because that's what I did,' she shared.

Lauren then offered up one very surprising example of one of her childhood passions: snakes.

'You know I still love snakes...' she revealed. 'Imagine having no arms or legs! And people are trying to kill you in every direction you go in.'

Although perhaps not the answer many might have expected from Lauren, the brand says that kind of out-of-the-box, boundary-breaking attitude is exactly why StriVectin was so keen to sign Lauren on as its first celebrity favce.

'With Lauren, we have really met our match,' StriVectin CEO Joan Malloy said in a statement. 'We've wanted to work with her for quite some time.

'She redefined beauty when she popped on the scene five decades ago - and she's still doing it today. She's showing up still, again and again, to show all women that life doesn't end at 40.

'We're inspired by her intelligence, resilience, authenticity and fierce determination. We see her as a real partner, with a shared passion and purpose.

'We're not just interested in her face - we want her voice and opinions as well.'