Adopt cutting edge approaches in
Phenotypic Drug Discovery
“
Will your screening assay system translate to clinics ? Introducing...
OncoPrime
TM
“
What can be a better model than diseased cells... When that's what we intend to treat ! Highly complex
Simple
OncoPrime
TM
Cell lines with aberrant mutations not found in primary tumor
Organotypic, 3D cell culture Spheroid, Monolayers & Co-culture
Target based assays ignore the big picture
Diseased cells from patient samples
Early
>30
passage
passages
More clinically relevant
Less physiological
Do you really know what cells you are working with ? Recent studies suggest that only 40% of established cell lines are useful for drug discovery. Historically most drugs were discovered by phenotypic screens only Primary cell based phenotypic screening is the way to go...
https://www.facebook.com/saarumsciences https://www.linkedin.com/company/saarum-sciences http://twitter.com/saarumsciences
SAARUM SCIENCES Phenotypic Platforms for Drug & Biomarker Discovery