Aptamers Market - Technology Trend Analysis By Applications Therapeutics, Diagnostics, Biosensors, Drug Discovery, Biomarker Discovery, Research Applications with Market Landscape Analysis Global Forecasts to 2018 Released On 21th June 2014
Aptamers is an emerging market, widely considered as a rival or substitute to antibodies in the scientific industry. It is poised to grow rapidly in various application areas, including therapeutics and diagnostics. The global aptamers market is valued at $287 million in 2013 and is expected to reach $2.1 billion by 2018. Aptamers existed in parallel with antibodies for two decades, but its market potential was not utilized, even to a fraction of antibodies. However, the achievement of Macugen has given a boost to the aptamer field. The list of promising aptamers in the clinical trials pipeline estimates that these synthetic chemical antibodies will soon surpass monoclonal antibodies in therapeutics, diagnosis, and imaging. With technological merits over antibodies, the aptamers market is poised to grow at par with antibodies in the next 10-15 years. JSB Market Research Pvt. Ltd.
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Though there are just < 60 companies (biotech and pharmaceutical) working on aptamers, there are quite a number of research groups working on diverse applications of aptamers, particularly in studying key target molecules involved in cardiovascular diseases, infectious diseases, and against viral antigens. Hundreds of research articles have been published and a lot of patents granted and filed for this technology. The aptamers market is analyzed both in terms of qualitative, i.e. technological and quantitative, i.e. revenue, perspectives. The technological analysis includes discussion on inherent characteristics and capabilities of aptamers over antibodies and the various applications where aptamers can find its place. The market revenue analysis includes market segmentation and the expected market position by 2018, with the projected growth rate. The aptamers market is classified by geography, application segments and aptamer type. The application segments are further divided as therapeutics, diagnostics, biosensors, drug discovery, biomarker discovery, and research applications. The advantages of chemically modified aptamers and low production cost compared to antibodies aid the growth of the market. However, the reduced market acceptance compared to the antibodies and increased time consumption for screening using SELEX will hamper the growth of this market, to a certain extent. While aptamer technology has existed for over two decades, the challenges imposed on the development of aptamers for small molecules has resulted in very few novel aptamers that can bind to practical small molecular targets. Nevertheless, there are many opportunities for the innovative application of small molecule binding aptamers in biosensing, drug discovery, diagnostics and therapeutics. Besides a discussion on the properties of aptamers in the technological analysis, the basics on nucleic acid aptamers, peptide aptamers and the SELEX method for their synthesis are also discussed. Research applications are specifically discussed regarding aptamers use in flow cytometry, reagents and assays, mass spectrometry and western blotting. In addition, a number of therapeutic targets that are validated by basic research have been displayed under the therapeutics application segment. The complete value chain of the aptamers market is schematically represented and the significance of each stakeholder has been briefed. JSB Market Research Pvt. Ltd.
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Apart from the technological and market analysis, the investor climate has been assessed by tracking the complete investor network and collecting data on funds/grants and investments made towards the aptamers. Insights on current and future technological investment trends have also been discussed. The adoption and developmental potential of the aptamers technology market has been discussed on a geographic basis, i.e. North America, Europe, Asia-Pacific, and Rest of the world, by taking select countries that are poised to have a greater market value during the forecast period. In brief, this research report provides: A detailed description of the global technology developments and evolving trends in the aptamers field with key prominence on research innovations, collaborative efforts, and investments for aptamers. A close view on the aptamer based drug development for treatment of specific diseases by providing details and status of current aptamer drugs in pipeline. impact analysis of major drivers and restraints influencing the adoption and growth of the aptamers market during the period of 2013to 2018. Porters five forces analysis and SWOT analysis. Market size - global market forecast for 2013-2018, including demand side analysis and strategic recommendations for technology/product developers. Competitive landscape based on the analysis of key patents and research publications. Scope of the Report This research report categorizes the global aptamers market into geography, applications, and aptamer type. The applications market is further broken down by geography, with exhaustive revenue analysis for 2012 and 2013, as well as the forecast up to 2018. Global Aptamers Market - By Application JSB Market Research Pvt. Ltd.
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Therapeutics Diagnostics Biosensors Drug discovery Biomarker discovery Research applications Global Aptamers Market - By Aptamer Type Nucleic acid aptamers Peptide aptamers Global Aptamers Market - By Geography North America Europe Asia Pacific Rest of the World (RoW) Table of Contents 1 INTRODUCTION 18 1.1 Logical Assumptions in this Study Based on Reliable Sources 1.2 Key Take-Aways 1.3 Report Scope 1.4 Research Methodology 1.5 Key Data Points from Secondary and Primary Sources 2 EXECUTIVE SUMMARY 25 3 APTAMERS TECHNOLOGY LANDSCAPE ANALYSIS 29 3.1 Technology Overview 3.2 History & Milestones of Aptamers 3.3 Aptamers vs Antibodies 3.4 Aptamer Types 3.4.1 Nucleic Acid Aptamers JSB Market Research Pvt. Ltd.
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3.4.2 Peptide Aptamers 3.5 Aptamer Synthesis & Modifications 3.6 Applications 3.6.1 Therapeutics 3.6.1.1 Different Targets of Therapeutic Interest 3.6.2 Diagnostics 3.6.3 Biosensors 3.6.4 Drug Discovery 3.6.5 Biomarker Discovery 3.6.6 Research Applications 3.6.6.1 Reagents & Assays 3.6.6.2 Flow Cytometry 3.6.6.3 Mass Spectrometry 3.6.6.4 Western Blotting 3.7 Technology Value Chain Analysis 3.8 Aptamers Technology Innovations And Products With Applications 4 APTAMERS MARKET LANDSCAPE ANALYSIS 56 4.1 Aptamers Market Segmentation 4.2 Aptamers Technology - Global Impact 4.3 Market Forecast (2013 - 2018) Overview 4.4 Global Aptamers Market Revenue Forecast (2013-2018) 4.4.1 Global Aptamers Market Revenue By Geography 4.4.1.1 North America 4.4.1.2 Europe 4.4.1.3 Asia Pacific 4.4.1.4 Rest of the World 4.4.2 Global Aptamers Market Share By Geography 4.4.2.1 North America 4.4.2.2 Europe 4.4.2.3 Asia Pacific 4.4.2.4 Rest of the World 4.4.3 Global Aptamers Market Revenue By Application Segments 4.4.3.1 Global Aptamers Market Share By Segments 4.4.3.2 Therapeutic Aptamers Market By Region 4.4.3.3 Diagnostics Aptamers Market By Region 4.4.3.4 Biosensors Aptamers Market By Region 4.4.3.5 Drug Discovery Aptamers Market By Region JSB Market Research Pvt. Ltd.
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4.4.3.6 Aptamers Biomarker Discovery Market By Region 4.4.3.7 Aptamers Research Applications Market By Region 4.4.4 Global Aptamers Market Revenue By Aptamer Type 4.4.4.1 Nucleic Acid Aptamer Market By Region 4.4.4.2 Peptide Aptamer Market By Region 4.4.4.3 Nucleic Acid and Peptide Aptamers Market Share By Region 4.5 Market Dynamics 4.5.1 Drivers - Explanation 4.5.1.1 Impact Analysis by Timeline 4.5.2 Restraints Explanation 4.5.2.1 Impact Analysis by Timeline 4.6 Swot Analysis 4.7 Porters Five Forces Analysis 5 TECHNOLOGY INVESTMENT POTENTIAL 92 5.1 Investment Climate Assessment 5.2 Investor Network 5.3 Some Funds and Investments on Aptamers 5.4 Some Funds and Investments from NIH By Fiscal Year 5.5 Some Funds and Investments from NIH By Its Associated Institutes/Centers (Fy 2008-2013) 5.6 Insights on Current and Future Tech-Investment Trends 6 APTAMERS TECHNOLOGY ADOPTION AND DEVELOPMENT POTENTIAL 104 6.1 Geographic Adoption And Development Potential - Overview 6.2 North America 6.3 Europe 6.4 Asia-Pacific 6.5 Row Selected Countries 6.6 Demand Side Analysis 6.7 Technology Roadmap 7 APTAMERS COMPETITIVE LANDSCAPE 114 7.1 Competitive Landscape Analysis 7.2 Key Acquisitions/Partnerships/Agreements/Collaborations (2009 2013) 7.3 Startups and Spinoffs Based on Aptamers Technology 7.4 Clinical Trials of Aptamers By Different Properties (Anti-Coagulant Aptamers, Anti-Angiogenic Aptamers, Anti-Oncogenic Aptamers, Anti-Diabetic Aptamers) JSB Market Research Pvt. Ltd.
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7.4.1 Apamer Based Drugs in Clinical Trials 8 INTELLECTUAL PROPERTY AND RESEARCH STRENGTH ANALYSIS 122 8.1 Selected Aptamer and Selex Patents 8.2 IP Strength Analysis of Aptamers 8.3 Proprietary Technologies Based on Aptamers 9 ANALYST INSIGHTS AND RECOMMENDATIONS 130 9.1 Analyst Insights 9.2 Strategic Recommendations for Technology & Business Investors 9.3 Open Opportunity Invitations in the Field for Business Development List of Tables TAB - 1 Global Aptamers Market, 2013 - 2018 ($Million) 60 TAB - 2 Global Aptamers Market, By Geography, 2013 - 2018 ($Million) 62 TAB - 3 GLOBAL APTAMERS MARKET REVENUE, BY APPLICATION SEGMENT, 2013 2018 ($MILLION) 65 TAB - 4 THERAPEUTIC APTAMERS MARKET, BY GEOGRAPHY, 2013 - 2018 ($MILLION) 68 TAB - 5 DIAGNOSTICS APTAMERS MARKET, BY REGION, 2013 - 2018 ($MILLION) 70 TAB - 6 BIOSENSOR APTAMERS MARKET, BY GEOGRAPHY, 2013 - 2018 ($MILLION) 72 TAB - 7 DRUG DISCOVERY APTAMERS MARKET, BY GEOGRAPHY, 2013 - 2018 ($MILLION) 74 TAB - 8 APTAMERS BIOMARKER DISCOVERY MARKET, BY GEOGRAPHY, 2013 - 2018 ($MILLION) 76 TAB - 9 APTAMERS RESEARCH APPLICATIONS MARKET, BY GEOGRAPHY, 2013 2018 ($MILLION) 78 TAB - 10 GLOBAL APTAMERS MARKET, BY TYPE, 2013 - 2018 ($MILLION) 80 TAB - 11 NUCLEIC ACID APTAMERS MARKET, BY GEOGRAPHY, 2013 - 2018 ($MILLION) 81 TAB - 12 PEPTIDE APTAMERS MARKET, BY GEOGRAPHY, 2013 - 2018 ($MILLION) 82 TAB - 13 Funds by NIH & Associated Centers 2008-2013 ($Million) 100 TAB - 14 Projects and Funds by NIH & Associated Centers 2008-2013 ($Million) 101 List of Figures FIG - 1 GLOBAL MARKET OF APTAMERS 2013 2018 ($MILLION) 26 FIG - 2 GLOBAL MARKET OF APTAMERS 2013 2018 ($MILLION) 60 FIG - 3 GLOBAL APTAMERS MARKET REVENUE, BY GEOGRAPHY, 2013 2018 ($MILLION) 63 JSB Market Research Pvt. Ltd.
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FIG - 4 GLOBAL APTAMERS MARKET SHARE BY GEOGRAPHY, 2013 64 FIG - 5 GLOBAL APTAMERS MARKET SHARE BY GEOGRAPHY, 2018 66 FIG - 6 GLOBAL APTAMERS TECHNOLOGY MARKET REVENUE, BY APPLICATIONS, 2013 2018 ($MILLION) 66 FIG - 7 GLOBAL APTAMERS TECHNOLOGY MARKET SHARE, BY APPLICATIONS, 2013 2018 67 FIG - 8 GLOBAL APTAMERS MARKET SHARE BY SEGMENTS, 2013 68 FIG - 9 GLOBAL APTAMERS MARKET SHARE BY SEGMENTS, 2018 69 FIG - 10 THERAPEUTIC APTAMERS MARKET, BY REGION, 2013 2018 ($MILLION) 70 FIG - 11 THERAPEUTIC APTAMER MARKET BY REGION, 2013 71 FIG - 12 THERAPEUTIC APTAMER MARKET BY REGION, 2018 72 FIG - 13 DIAGNOSTICS APTAMERS MARKET, BY REGION, 2013 2018 ($MILLION)73 FIG - 14 DIAGNOSTICS APTAMERS MARKET BY REGION, 2013 74 FIG - 15 DIAGNOSTICS APTAMERS MARKET BY REGION, 2018 75 FIG - 16 BIOSENSOR APTAMERS MARKET, BY REGION, 2013 2018 ($MILLION) 76 FIG - 17 BIOSENSOR APTAMERS MARKET BY REGION, 2013 77 FIG - 18 BIOSENSOR APTAMERS MARKET BY REGION, 2018 78 FIG - 19 DRUG DISCOVERY APTAMERS MARKET, BY REGION, 2013 2018 ($MILLION) 79 FIG - 20 DRUG DISCOVERY APTAMERS MARKET BY REGION, 2013 80 FIG - 21 DRUG DISCOVERY APTAMERS MARKET BY REGION, 2018 80 FIG - 22 APTAMERS BIOMARKER DISCOVERY MARKET, BY REGION, 2013 2018 ($MILLION) 81 FIG - 23 APTAMERS BIOMARKER DISCOVERY MARKET BY REGION, 2013 82 FIG - 24 APTAMERS BIOMARKER DISCOVERY MARKET BY REGION, 2018 83 FIG - 25 APTAMERS RESEARCH APPLICATIONS MARKET, BY REGION, 2013 2018 ($MILLION) 90 FIG - 26 APTAMERS RESEARCH APPLICATIONS MARKET BY REGION, 2013 100 FIG - 27 APTAMERS RESEARCH APPLICATIONS MARKET BY REGION, 2018 101 FIG - 28 GLOBAL APTAMERS MARKET, NUCLEIC ACID APTAMER, 2013 2018 ($MILLION) 127 FIG 29 GLOBAL APTAMERS MARKET, PEPTIDE APTAMER, 2013 2018 ($MILLION)127
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