For well over a century, economists, policymakers, and idealists have talked about an end to poverty. Yet hunger, destitution, and homelessness continue to afflict even the wealthiest communities, including New York City. We find ourselves today, however, with many promising developments on the horizon. We are in the midst of what has been described as a social enterprise revolution: From mobile health to microfinance to new approaches to educating and training those born or living in poverty, there are innovative efforts afoot to bring us closer to actually ending poverty. At the same time, a new generation of researchers is applying the latest ideas and techniques from the social sciences to better understand why poverty has been so persistent.