DermaSilk Intimo

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DermaSilk changes lives

THE NEW INTIMATE DERMA SilkINTIMO has been created using medical technology which has revolutionised the management of sensitive skin conditions such as eczema.

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Thanks to an innovative combination of Medical Quality Silk fabric and a permanently bonded antimicrobial, DERMASilkINTIMOTM soothes inflamed skin and helps to protect against bacterial and fungal infections such as Thrush.

DERMA SilkINTIMOTM supports the

maintenance of an optimum pH and humidity in the vulvar area and soothes irritation thereby minimising symptoms such as itching, burning and pain without altering the natural resident skin flora.

The therapeutic effect of these innovative undergarments has been proven in controlled clinical studies on patients suffering from skin conditions involving the genital area such as vulvovaginal Thrush and Lichen Sclerosus.

DERMA SilkINTIMOTM underwear has been styled

and made in Italy to ensure that the majority of women will find a design of briefs to suit their lifestyle.

These are comfortable and versatile. They fit the majority of figures, thanks to the elasticity of the fabric which can stretch up to twice their initial size.The absence of side seams and elastic around the leg also aids comfort.

We’ve not forgotten the rest of the family so DERMA SilkINTIMOTM also includes therapeutic underwear for MEN and CHILDREN.

DERMA SilkINTIMOTM underwear is registered as a CLASS 1 MEDICAL DEVICE, patented, and produced in Italy

by Alpretec Srl, a UNI EN ISO 9001:2008 company, specialising in high-tech fabrics for health.

fashionable and comfortable clothing to stretch and fit so that they feel like they are a part of you

THE VAGINAL ECOSYSTEM NATURE’S NATURAL DEFENCE

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ature has developed a unique way of

protecting these delicate areas from infection – by using a carefully controlled balance of several friendly microbes on the skin which work together in harmony to maintain a slightly acidic pH level of around 4.

This is fundamental for genital health since it acts as a natural defence against invading microbes.

When The Ecosystem Is Altered‌ and the pH undergoes changes, problems may arise such as itching and burning.This may also trigger conditions that encourage the onset of bacterial and mycotic infections.

Common triggers may include stress, hormonal factors and antibiotic therapies, all of which can provoke an alteration of the vaginal microflora.

You Can Also Alter The Equilibrium...

60% of women suffer from problems that could easily be avoided by making small changes in their lifestyle. Certain widespread and apparently harmless habits may alter the microflora and the pH of the genital area.

Among the most common, personal hygiene using unsuitable detergents and the prolonged use of panty liners and tight synthetic garments can limit ventilation of the area, increasing humidity and promoting the development of pathogenic microorganisms.

In addition, in recent years there has been an increased use of odour-reducing sprays and undergarments treated with slow release antimicrobial agents such as silver ions, Triclosan, etc.*. These antimicrobials are absorbed by the skin and mucosa and can alter the resident flora, destroying the equilibrium of the vaginal ecosystem and leaving the area without it’s natural defences.

When the vaginal ecosystem no longer guarantees natural protection, DERMA SilkINTIMO restores the equilibrium.

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* In vitro evaluation of the bio-activity of different fabrics for underwear against Lactobacillus acidophilus, Staph. Epidermidis, Staph. Aureus and Candida Albicans (Vittorio Sambri et al., Poster presentation - 28th Congress of the European Academy of Allergy and Clinical Immunology, EAACI 2009).

DERMASILK INTIMO PROTECTS AS A SECOND SKIN Thanks to the innovative combination of Medical Quality silk plus a permanent antimicrobial finish,

DERMA SilkINTIMOTM

Quickly reduces itching, burning and other inflammatory symptoms.

It has a protein structure similar to that of human hair and is completely free from sericin, a substance present in ordinary, non-medical quality silk which, in rare cases, may cause allergic reactions. It is free from dyes and has not undergone any processes in its manufacture that could irritate the skin and mucosa.

DERMA SilkINTIMOTM

Helps control and prevent bacterial and fungal infections without altering the natural levels of friendly resident microbes.

Helps keep the vulvar area fresh and dry thanks to the fabric design which enhances free movement of air and moisture.

(DermaSilk速 absorbs as much as 30% of its own weight in moisture whilst still remaining dry). In this way it efficiently reduces excess temperature and humidity, discouraging the development of vulvovaginal infections.

Provides a soothing and healing environment which reduces irritation and assists in the repair and regeneration of skin and surrounding soft tissues.

is made of pure fibroin, the inert part of the silk.

DERMA SilkINTIMOTM achieves its

ability to stretch to twice its size by an innovative process which overlays the DermaSilk fibroin silk completely around an elastane core. We have developed this fabric to ensure that there is no contact between the elastane and your skin, you only feel the soft touch of TM DermaSilk. All DERMA SilkINTIMO garments contain 96% DermaSilk and 4% encased elastane.

pH

helps maintain optimum pH levels

REMOVES HARMFUL MICROBES WITHOUT AFFECTING THE RESIDENT FLORA Fabrics are an ideal habitat for microbes (bacteria, fungi and yeasts) as they provide them with warmth, moisture and food. Despite regular washing they can be a source of bacterial or fungal infection particularly when the barrier effect of the skin has been compromised by skin conditions or lowered immunity. One way of protecting clothing is to add an antimicrobial finish to the fabric.

The antimicrobial in DERMA SilkINTIMO protects the fabric from microbial contamination thereby helping to control inflammation and bacterial and fungal infections of the skin without altering the natural resident flora.

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Unlike conventional antimicrobial agents, which release chemical substances that are absorbed by the skin and kill all micro-organisms on it, the antimicrobial used in DermaSilk速 does not release any chemicals. It is fixed permanently on the silk fibre (it does not wash out and remains active for the entire life of the product) and acts as a physical killer of pathogenic microbes by destroying their cell membrane.

DERMA SilkINTIMOTM Therefore Protects Against Infection In Two Ways: As microbes cannot grow on the fabric, there is no migration of them from the fabric towards the skin and mucosa.

The microbes that are already infecting the skin and mucosa are rendered inactive when they come in contact with the fabric.

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DermaSilk ® FAST RESPONSE STINGING EVEN IN SERIOUS ITCHCONDITIONS 20

Severity

15

10 5

DermaSilk® has been studied in a number of gynaecological0 conditions, such as4 chronic 1 2 5 3 vulvovaginitis, vulvar and perineal herpetic Months lesions and vestibulitis. 94 women were 50 DermaSilk ® Briefs (47 women) allocated either or cotton briefs (47 women) in addition to 40 normal medical therapy. All the women were asked to complete a questionnaire before the study started, after 7 days and 14 days to 30 Severity assess their pain and irritation levels caused by their condition.

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6

100

Cotton

86%

80

STINGING

shown to be very effective in DermaSilk® was 10 the short-term relief of symptoms and produced a higher percentage of recovery than those 0 1 2 who 4 5 3 wore that occurred in persons cotton Months underwear.

Derma Silk

60 40

48.5% 28%

20

6

3%

0 7 Days

14 Days

“Some patients, having obtained beneficial effects, have spontaneously decided to wear the product again when the first symptoms of a relapse occur. Other patients use them generally as a form of prevention, during sporting activities” “Clinical Study on efficacy of undergarments manufactured with medicated silk DermaSilk® in some gynaecological disease” M. M. Anceschi, G. Marcellini Hercolani-Gaddi, Department of Gynaecology, Perinatology and Puericulture, University of Rome “La Sapienza”.

The patients reported an immediate sense of wellbeing in the initial phase of application, even in the first 12 hours,‌ with a decrease of itching within one hour.

Lichen Sclerosus, REDUCTION OF SYMPTOMS WITHIN A MONTH The study assessed the efficacy of DermaSilk速 in comparison with cotton in women suffering from 42 patients with a history of Lichen Sclerosus were allocated to receive either DermaSilk or cotton briefs in addition to their normal steroid therapy.

Results Symptoms such as itching, pain, burning, dryness and dyspareunia (painful sex) - typical of the most widespread vulvar pathologies - were drastically reduced within the first month when using DermaSilk速.

At the end of the 6 month study, the improvement obtained in the DermaSilk速 group was much more marked than in the Cotton group. In many cases the symptoms in the DermaSilk group disappeared altogether!

All patients stated that they wanted to continue using DermaSilk速, even after the observation period.

Reduces Burning

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Severity

40 30 20 10 0

0

1

Months

DermaSilk

6

Cotton

Reduces Itch

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Severity

20 15 10 5 0

0

DermaSilk

1

Months

6

Cotton

DermaSilk ® IN RECURRENT THRUSH REDUCES SYMPTOMS AND RECURRENCES A Clinical Study looked into the effect of using DermaSilk® underwear in the treatment of recurrent vaginal thrush in women who had not fully responded to standard antifungal therapy using The 96 patients involved in the study were divided into two groups with half wearing only DermaSilk® underwear and the other half only wearing pure cotton underwear for 6 months. Both groups continued to take the same fluconazole capsules as before.

Results In all stages of the study, the women in the DermaSilk® group reported a much more marked and progressive improvement than the ones in the cotton group with regards to: itching, burning, redness (erythema), vulvar irritation and swelling (oedema). The improvements in those who used DermaSilk® continued for the entire duration of the study, whereas improvements in the patients who wore cotton underwear ceased to improve after 3 months.

The study also showed that the use of DermaSilk® rather than cotton underwear helped reduce the number of relapses.

No of patients with symptom

Presence Of Erythema

50 40 30 20 10 0

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0

Months

DermaSilk

No of patients with symptom

66.7% of DermaSilk patients suffered only 0 -1 recurrence but 60.5% of cotton patients suffered 2 recurrences or more.

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3

Cotton

Presence Of Pruritus

50 40 30 20 10 0

0

DermaSilk

1

Months

3

6

Cotton

“Use of DermaSilk briefs in recurrent vulvovaginal candidosis” A. D’Antuono, S. Bellavista, N. Banzola, V. Gaspari, A. Patrizi, Dermatological Clinic - University of Bologna - (poster presented at the 86th SIGO Congress - 51st AOGOI Congress; Milan 2010).

WOMAN

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Comfortable and versatile they fit almost

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Slips, mini slips, micro slips, shorts, mini shorts and soft cup bra in Medical Quality Silk. Comfortable and versatile, they fit almost any figure thanks to the (2x) elasticity of the fabric and the absence of side seams and elastic around the leg.

Gussets in silk piquĂŠ.

any figure Available In 3 Sizes UK Ladies Size

XS/S M/L XL/XXL

(6-10) (12-16) (18-22)

WOMAN Soft Cup Bra

Shorts

Mini Shorts

Slip

Mini Slip

Micro Slip

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Brief

Briefs and Boxers in Medical Quality Silk. Comfortable and versatile, they fit almost any figure thanks to the elasticity of the fabric and the absence of side seams.

Available In 3 Sizes: XS/S (Waist 26-30 ins) M/L (32–36 ins) XL/XXL (38-44 ins)

Boxer

BOYS GIRLS Girls

Boys and Girls briefs in Medical Quality silk. Practical and very comfortable thanks to the elasticity of the fabric and the absence of side seams.

Available In 2 Sizes: Age 3-6 and Age 7-10

Boys

CARE INSTRUCTIONS DERMA SilkINTIMOTM garments

have been designed to last as long as conventional underwear providing that the care instructions are followed correctly.

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Please wash by hand or in the washing machine on a delicate cycle at 30°C using non-biological (enzyme free) detergent.

DermaSilk® is an animal protein very similar to human hair.

It can be washed with a little neutral shampoo (without conditioner or other additives).

Do not use bleach, fabric conditioners, stain removers or disinfectants. It is important to rinse repeatedly in plenty of water.

Do not spin-dry, tumble-dry, or dry in direct contact with sources of heat (radiators).

To remove any stains, soak the garments in warm water and bicarbonate (2 spoons of bicarbonate per litre at 60°C) for 2-3 hours before washing normally.

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ANY QUESTIONS? Please call us on 01234 834614 and Jo or Chesca will be able to answer your questions in confidence and How Do I Order DERMA SilkINTIMO Garments?

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www.dermasilkintimo.co.uk If you are paying in a currency other than £ Sterling (e.g. Euro), please order as normal. The prices will be shown in Sterling but your receipt will be produced in your local currency.

+44 (0)1234 834614 Call our order line during office hours and place your order using a credit or debit card. Our team can also answer many questions to help you in your selection.

After office hours please leave a message and a contact telephone number and we’ll ring you back as soon as possible.

+44 (0) 1234 834615 Feel free to send orders via fax at any time. Simply fill out the order form and fax it to us on.

If you are UK resident you can post the order form together with either your Credit Card details or cheque made payable to ‘Espère Healthcare Ltd.’ Do not forget to include your delivery address and a contact phone number.

Order Line +44 (0)1234 834614 Espère Healthcare Ltd • Suite F11 • Bedford i-lab • Bedford • MK44 3RZ

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PART OF ME www.dermasilkintimo.co.uk