Vision
Value
Visibility Report Code :HC 1285
2016-2024
Global Biologics Drug Discovery Market Outlook 2024: Global Opportunity & Growth Analysis, 2016-2024
+1-646-568-7747 +1-437-886-1181 +44-203-318-6627 +91-120-473-0422, +91-844-785-9968 sales@goldsteinresearch.com
99 Wall Street, Suite No:- 527, New York, NY 10005 United States of America Office No:- 504, 5th Floor, C-51, BSI Business Park, Sector-62, Noida, PIN:- 201301 India
www.goldsteinresearch.com
Published By: Goldstein Research Copyright
All Rights Reserved, Goldstein Research
www.goldsteinresearch.com
Executive Summary
Sample Request Global Biologics Drug Discovery Market Share(%), By Region-2016-2024
Global Biologics Drug Discovery Market Size USD (Billion). 2016-2024
XX%
CAGR: (2016-2024)
2016e
2017e
2018f
4.00 5.00 %% 45.0 21.0 0% 2016 0% 25.0 0%
2019f
Source: Goldstein Research
2020f
2021f
2022f
2023f
2024f
m a S
High Throughput Screening accounted for the highest market share XX% in Biologics Drug Discovery Market
In 2016,
Global Biologics Drug Discovery Market Share(%), By Technology-2016
XX%
XX% XX%
XX%
XX% XX% XX%
XX% XX%
Source: Goldstein Research
Copyright
Q-PCR DNA Microarrays Protein Microarrays Highthroughput screening Mass Spectrometry Gel Electrophoresis Chromatograph y Protein and Nucleic Acid Isolation Other technologies
All Rights Reserved, Goldstein Research
e l p North America
55.00 %
Source: Goldstein Research
APAC
25.00 % Latin America
Middle East & Africa
Source: Goldstein Research
With
XX% share in 2016, North America region dominated the collective Global Biologics Drug Discovery market
Global Biologics Drug Discovery Market Share(%), By End User-2016
45.00 %
Europe
4.00% 5.00% 21.00 45.00 2024 % %
Outsourcing (Contract Research Organization)
Global Biologics Drug Discovery Market Share(%), By Phase of Discovery-2016
40.00 %
30.00 %
15.00 15.00% %
Insourcing (Within the Organization)
Source: Goldstein Research
www.goldsteinresearch.com
Target Identification/Validation
Hit Generation
Lead Identification
Lead Optimization
Key Findings
Sample Request
The global biologics drug discovery market was estimated to be USD XX billion in 2016 and is estimated to grow over USD XX billion by 2024. Introduction of targeted therapies coupled with rising adoption of patient centric personalized medicine is expected to fuel the demand for biologics drugs in the future Geographically, biologics have registered near double digit annual growth rate, whereas, the pharmaceutical drugs registered only single digit annual growth rate, in the past five years. This double digit growth was largely fueled by the substantial investments of the major pharmaceutical companies, who realized the potential of the market quite early The global biologics drug discovery market can be segmented based on the basis of phase of discovery into target identification, hit generation, lead identification & lead optimization. The major contributor towards the market in 2016 was the lead optimization phase. Based on the manufacture type, the market is segmented into in-house & outsourced. The in-house market for the global biologics drug discovery was estimated to be USD XX billion in 2016. The CAGR was highest for the out-sourced manufacturing Biologics are expected to contribute 50% to the sales of the top 100 products during the forecast period. This will lead to increased investment in the global biologics drug discovery market in future. For instance, in 2016, among the most valued R&D projects were Roche' Ocrelizumab & Sanofi's Dupilumab. And in 2017, Ocrevus (Ocrelizumab) & Dupixient (dupilumab) were among the top 2 product launches so far The market for the drug discovery of monoclonal antibody is expected to reach USD XX billion by 2024. The next contributing segment is recombinant proteins. Geographically, the largest contributor to the growth of the global biologics drug discovery market was found to be North America due to the presence of pharmaceutical companies involved in R&D of biologics
Increasing presence of Contract Research Organizations
Increasing investment in the biologics drug discovery
Introduction of targeted therapies
Global Biologics Drug Discovery Revenue (USD Billion) Asia-Pacific
Copyright
North America
2016
USD XX Billion
USD XX Billion
2024
USD XX Billion
USD XX Billion
All Rights Reserved, Goldstein Research
www.goldsteinresearch.com
rising adoption of patient centric personalized medicine
Overview of Discovery Process
Sample Request 7. Clinical Candidate mAb
1. Selected Targets
2. Target Validation
3. Screening Preparation
4. Hit Generation & Lead Selection
5. Lead Optimization & Characterization
6. Candidate Selection
Collect evidence to support target rationale
Generate reagents for assay development & screening
Generate antibody hits using display technology and hybridoma technology including the use of human antibody transgenic mice
Humanization
Examination of scientific data package
Fc engineering
Experimentally validate the target Develop binding and functional assays
Select lead molecules with desired function and favorable biochemical and biophysical properties
Develop animal efficacy models
Demonstrate in vivo efficacy
Establish project plan
Copyright
In vivo efficacy of optimized lead Biochemical and biophysical characteristics (expression, aggregation)
Obtain key stakeholder’s approval
Form project team
Affinity maturation
All Rights Reserved, Goldstein Research
Safety assessment Commercial assessment Legal evaluation Clinical plans
Exploratory PK.PD Clinical biomarker plan Exploratory safety study
Define and execute strategies for evaluating non-cross reactive antibody
Risk assessment
Manufacturing Assessment Map Epitope Biomarker Development
www.goldsteinresearch.com
Patient stratification plans Regulatory plans Manufacturing plans
Global Biologics Drug Discovery Market Size (USD Billion) & Growth Analysis Global Biologics Drug Discovery Market Size (USD Billion)-2016-2024 XX
XX
XX% XX%
XX
XX
XX%
XX
XX
e l p
XX%
XX
XX%
XX
XX
XX%
XX
XX%
XX XX
XX
XX
XX XX
Global Biologics Drug Discovery Market Y-O-Y Growth (%) Analysis-20162024
XX
XX
XX%
m a S
XX% XX%
XX% XX% XX% XX% XX%
XX% XX%
XX%
XX
XX% XX%
XX
XX%
2015
XX
2015
2016
2017
Source: Goldstein Research
2018
2019
2020
2021
2022
2023
2024
2016
2017
2018
2019
2020
2021
2022
2023
Source: Goldstein Research
North America Biologics Drug Discovery Industry size is anticipated to expand at a compound annual growth rate of XX% during the forecast period i.e. 2016-2024. Further, Biologics Drug Discovery revenue increased from USD XX billion in 2015 to USD XX billion in 2016 Novartis is adding jobs to its biologics manufacturing operations even as the Swiss company makes cuts across other parts of its global operations, including traditional manufacturing. Novartis’ cross-town rival Roche, for example, laid out plans in 2013 to invest nearly USD XX billion to beef up its biologics manufacturing operations across the globe. Eli Lilly recently moved forward with plans to expand a biologics plant in Ireland, with plans to add 130 jobs there South Korea’s Samsung has even jumped into the fray with no prior experience in drug production, believing that its phone and chemical production experience would help it excel in the market Copyright
All Rights Reserved, Goldstein Research
www.goldsteinresearch.com
2024
Market Dynamics of Global Biologics Drug Discovery Market
Sample Request
Growth Drivers
Growth Barriers
Healthy appetite for M&A seen across the board
Limitations in biological activity
Prescription drug sales are set to advance
More costly to develop than small molecule therapeutics General Trend
Highly Complex
Moderately Complex
Waived
Technology Copyright
All Rights Reserved, Goldstein Research
www.goldsteinresearch.com
Global Biologics Drug Discovery Market Share(%) - By Product Type & Technology, 2016-2024 Key Findings
Global Biologics Drug Discovery Market Share, By Technology, 2016-2024
XX%
XX%
XX%
XX%
XX%
2016
XX% XX%
XX% XX%
Q-PCR DNA Microarrays Protein Microarrays Highthroughput screening Mass Spectrometry Gel Electrophoresis Chromatograph y Protein and Nucleic Acid Isolation Other technologies
XX%
XX%
XX%
Investing in biotech R&D has yielded better returns than the pharma-industry average. The current biologics-development pipeline supports an outlook of continued healthy growth. The number of biotech patents applied for every year has been growing at 25 percent annually
XX%
e l p XX%
2024
XX%
XX%
XX% XX%
m a S
Source: Goldstein Research
There are currently more than 1,500 biomolecules undergoing clinical trials, and the success rate for biologics has so far been over twice that of small-molecule products, with 13 percent of biopharma products that enter the Phase I trial stage going on to launch
The success of the clinical pipeline will lead to an unprecedented number of new molecule launches, rising from a handful a few years ago to 10 to 15 annually, as biopharma products make up an increasing share of new approvals from the US Food and Drug Administration in the future
Global Global Biologics Biologics Drug Drug Discovery Discovery Market Market Y-O-Y Y-O-Y Growth, Growth, By By Product, Product, 201620162024 2024
Global Global Biologics Biologics Drug Drug Discovery Discovery Market Market Size Size (USD (USD Billion), Billion), By By ProductProduct2016-2024 2016-2024 XX
XX
XX
XX
XX
XX
2016
Monoclonal Antibodies
2024
Recombinant Proteins
Source: Goldstein Research
Copyright
All Rights Reserved, Goldstein Research
Other Biologics
2015
2016e
2017f
2018f
2019f Y-o-Y
Source: Goldstein Research
www.goldsteinresearch.com
2020f
2021f
2022f
2023f
Global Biologics Drug Discovery (Billions) By Technology, 2016-2024 Technology
2016
2017
2018
2019
2020
Q-PCR
XX
XX
XX
XX
XX
DNA Microarrays
XX
XX
XX
XX
XX
Protein Microarrays
XX
XX
XX
XX
XX
High-throughput screening
XX
XX
Mass Spectrometry
XX
XX
Gel Electrophoresis
XX
XX
Chromatography
XX
XX
Protein and Nucleic Acid Isolation
XX
XX
Other technologies
XX
XX
2021
m a S
2022
2023
e l p
All Rights Reserved, Goldstein Research
CAGR(%)
XX
XX
XX
XX
XX%
XX
XX
XX
XX
XX%
XX
XX
XX
XX
XX%
XX
XX
XX
XX
XX%
XX
XX
XX
XX
XX%
XX
XX
XX
XX
XX%
XX
XX
XX
XX
XX
XX
XX
XX
XX
XX
XX
XX
XX
XX
XX
XX
XX%
XX
XX
XX
XX
XX
XX
XX
XX%
XX
XX
XX
XX
XX
XX
XX
XX%
Source: Goldstein Research Copyright
2024
www.goldsteinresearch.com
North-America Biologics Drug Discovery Market Size (USD Billion) & Y-O-Y growth (%),2016-2024 North-America Biologics Drug Discovery Market Size(USD Billion)2016-2024
182,928. 172,928. 4 4 152,928. CAGR: (2016-2024) 141,934. 4 131,569. 5 122,244. 113,569.4 105,774. 9 8 7 98,541.8
North-America Biologics Drug Discovery Market Share By Product, 2016-2024
XX%
e l p XX%
XX%
2016
m a S
XX%
2016e
2017e
2018f
2019f
Source: Goldstein Research
2020f
2021f
2022f
2023f
2024f
North-America Biologics Drug Discovery Market Size (USD Millions), By Country-2016-2024
2016 28.00% 15.00%
2024 35.00% 20.00%
U.S.
Source: Goldstein Research
Copyright
All Rights Reserved, Goldstein Research
Canada
XX%
XX% XX%
Q-PCR DNA Microarrays Protein Microarrays Highthroughput screening Mass Spectrometry Gel Electrophoresis Chromatograph y Protein and Nucleic Acid Isolation Other technologies
XX%
XX%
XX%
Source: Goldstein Research
XX%
XX% XX%
XX% XX%
2024
XX%
XX% XX% XX%
North-America Biologics Drug Discovery Market Size (USD Million), By End User-2016-2024
2016 20.00% 18.00%
Outsourcing (Contract Research Organization)
2024 25.00% 24.00%
Insourcing (Within the Organization)
Source: Goldstein Research
www.goldsteinresearch.com
Sample Request
About us Connect With Us: Published By: Goldstein Research
Vision
Value
Visibility Sample Request
About Us Based
in
U.S.,
Goldstein
Research
is
a
young
business consulting and market research firm with vast reach across America, Asia and parts of Europe and the Middle East. In the next five years, we strive to expand our reach to 50+ nations spanning across Europe, Asia and parts of the Middle East and Africa. We strive to realize a strong brand presence globally through our quality research and forecasting solutions. With 30+ domain experts and 50+ employees working day and night to crunch numbers and bring out the best and detailed market reports and forecasts, we strive to enable you to foresee upcoming market challenges and develop a robust business model and strategies, which would add to your profitability and market visibility as a brand. Our mission is simple: to develop insightful business solutions, help our clients make powerful future decisions to keep them well ahead of the game which is the market, and leave a mark across businesses and communities through our well-defined ideas and clear cut forecasts. Our mission is simple: to develop insightful business solutions, help our clients make powerful future decisions to keep them well ahead of the game which is the market, and leave a mark across businesses and communities through our well-defined ideas and clear cut forecasts.
Published By: Goldstein Research Copyright
All Rights Reserved, Goldstein Research
www.goldsteinresearch.com
Vision
Value
Visibility Sample Request
Contact Us: For Research & Sales Related Queries +1-646-568-7747 +1-437-886-1181 +44-203-318-6627 +91-120-473-0422, +91-844-785-9968 sales@goldsteinresearch.com
Corporate Office: 99 Wall Street, Suite No:- 527, New York, NY 10005 United States of America Office No:- 504, 5th Floor, C-51, BSI Business Park, Sector-62, Noida, PIN:- 201301 India www.goldsteinresearch.com Published By: Goldstein Research Copyright
All Rights Reserved, Goldstein Research
www.goldsteinresearch.com
Sample Request
thAnk you Connect With Us: Published By: Goldstein Research Copyright
All Rights Reserved, Goldstein Research
www.goldsteinresearch.com