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Nervous System and Brain Disorders

Dr. Arseny Finkelstein

Memory formation and neural plasticity

The brain is a highly plastic system that is constantly changing . Changes in interactions between neurons allow us to learn from experience and to create new memories . The longterm goal of Dr Finkelstein’s lab is to study what constitutes the building blocks of memory by literally watching how memories are formed using optical imaging of the living brain, and by implanting artificial memories directly into the brain using novel optogenetic methods . Dr. Finkelstein studies

Dr. Finkelstein, PhD, is in the Department of Physiology & Pharmacology in the School of Medicine and is affiliated with the Sagol School of Neuroscience . He completed his Ph . D. studies at the Weizmann Institute of Science and his postdoctoral training at Janelia Research Campus (Howard Hughes Medical Institute, USA). Dr. Finkelstein is a recipient of several awards including the Wolf Foundation award, Clore Foundation fellowship, The John F. Kennedy Prize (Weizmann Institute of Science), FENSKavli Network of Excellence PhD Thesis Prize, Young Investigator Award and the Capranica Prize from the International Society for Neuroethology, EMBO LongTerm Fellowship, Rothschild Fellowship for postdoctoral research, and is an Azrieli Foundation Early Career Faculty Fellow. https : //www. finkelstein . sites . tau . ac . il / memory formation processes using mice engaged in cognitively complex behaviors involving decision -making and navigation . The lab employs cutting edge microscopy techniques allowing turning on or off specific neurons in the brain, in combination with advanced computational methods for modeling and analysis of neural dynamics In addition to studying changes in neural interactions in the healthy brain, Dr. Finkelstein’s lab will study another important aspect of neural plasticity

– the reorganization of brain networks during neurodegeneration, with a focus on brain plasticity following stroke

Nervous System and Brain Disorders

Prof. Illana

Gozes

Therapeutics for autism and beyond

Prof. Gozes discovered and studies Activitydependent neuroprotective protein (ADNP), recognized as a leading gene accounting for 0 17 % of autism spectrum disorder (ASD) cases globally The Gozes laboratory focuses on genome editing, to test and develop therapeutics such as the ADNP enhancing fragment NAP (CP 201 ) and pipeline products, for effects on autism and other ASDrelated predicaments .

Prof. Gozes further discovered convergence among autism, schizophrenia, stressrelated ailments and https://www.adnpkids.com/illana -gozes.html

Prof. Gozes , PhD, (Emerita) is Head of the Dr. Diana and Zelman Elton (Elbaum ) Laboratory for Molecular Neuroendocrinology, and at the Department of Human Molecular Genetics and Biochemistry, the Adams Super Center for Brain Studies and Sagol School of Neuroscience. She is Chief Scientific Officer at Coronis Neurosciences,with her BSc, from Tel Aviv University, Direct PhD, from Weizmann Institute of Science, Israel, postdoc at MIT and Salk Institute, and was a Senior Scientist/Associate Professor at the Weizmann Institute and Fogarty -Scholar-in -Residence at the NIH, USA. Prof. Gozes has won many awards of excellence, including Tel Aviv University’s Vice President Award, Olson Prize, Julodan Prize, Teva Prize, Neufeld Award, Hanse -Wissenschaftskolleg (HWK) Fellowship, Humboldt Award, the Landau Prize for Life Achievements and the RARE Champion of Hope Award. She currently serves as Secretary of the European Society for Neurochemistry, is a member of the Israeli Ministry of Education, Council of Higher Education and is the Editor-in -Chief of the Journal of Molecular Neuroscience .

Alzheimer’s disease with ADNP playing a role in all of these diseases . As such, the Gozes laboratory strives to pave the way to novel diagnostics and treatments toward healthy development, maturation and aging of the brain .

TAU Faculty of Medicine

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