HOSPITALS Magazine 75

ACIBADEM UNIVERSITY

trains healthcare students to be future healthcare professionals.

ACIBADEM

LABMED

offers a wide range of services including pathology, food control, stem cell and cord blood bank within the laboratory framework.

AC BA C A A͘ develops turnkey hospital establishment projects.

Unveiling ACIBADEM Healthcare Ecosystem

Step into a world where healthcare is not just a service, but a carefully designed ecosystem centered around Patient Safety and Patient Satisfaction – Welcome to ACIBADEM. At the forefront of innovative medical care, ACIBADEM's healthcare model is a testament to its unwavering commitment to excellence. Every facet of the healthcare journey is seamlessly integrated, with ACIBADEM collaborating with its supporting institutions at every step to mitigate risks and ensure service quality that aligns with ACIBADEM standards. Embark on a journey of cutting-edge medical services that transcend borders, as ACIBADEM extends its reach across Türkiye, Bulgaria, Macedonia, Serbia, and the Netherlands. Experience healthcare like never before, where your well-being takes center stage.

ACIBADEM MOBIL

provides emergency and home care services outside of the hospital.

ACIBADEM APLUS

addresses the hygiene and catering requirements of the hospitals.

ACIBADEM HEALTH POINT

ensures continuous support for patients from their arrival at Istanbul Airport until they return home, guiding them through their entire healthcare journey in Türkiye.

ACIBADEM TECHNOLOGY

develops and improves inhouse softwares including Hospital Information System and healthcare command center.

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Joint Commission International (JCI) offers a comprehensive framework and practical tools to guide your healthcare organization on its journey towards high reliability. We equip your leaders and staff with the knowledge, resources, and strategies needed to:

• Foster leadership commitment to zero harm, ensuring unwavering support for safety initiatives

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*The use of Joint Commission International (JCI) advisory services is not necessary to obtain a Joint Commission International Accreditation award, nor does it influence the granting of such awards.

RAMADAN

MUBARAK: A TIME FOR DEEP REFLECTION AND HOLISTIC WELL-BEING

As we welcome the sacred month of Ramadan, a period distinguished not only by its spiritual significance but also by its profound impact on mental and physical health, it becomes imperative for healthcare institutions across the Arab world to adapt. Recognizing the unique requirements of this holy month, hospitals and health centers have judiciously adjusted their schedules. This ensures that medical services remain at peak readiness, seamlessly accommodating the needs of those observing fasts, while also being well prepared for any emergent health issues.

In a concerted effort to support the well-being of the fasting community, multiple institutions, including research entities, counseling centers, and specialized media, have initiated comprehensive awareness campaigns. These initiatives are designed to educate on various health aspects during Ramadan, encompassing the correct approach to medication intake and treatment continuation for fasting individuals, recommended physical activities, optimal dietary habits, and essential tips to sustain robust health and vitality necessary for fulfilling daily responsibilities during the fast.

Beyond the physical and mental realms, Ramadan offers an unparalleled opportunity for spiritual rejuvenation, drawing individuals closer to divine consciousness. This spiritual enrichment inherently facilitates an environment conducive to nurturing physical and mental health, a synergy underscored by numerous studies attesting to the myriad health benefits of fasting. Hospitals and health centers, particularly in the Gulf region, are at the forefront, championing awareness and ensuring medical and logistical preparedness to offer unique care during this holy month.

Our team behind "The Arab Hospital" and "HOSPITALS" Magazine, alongside the platform "so7tak.com" website, and our social media channels, extends heartfelt Ramadan greetings to the Arab and Islamic communities worldwide. In this blessed period, we wish all our readers and followers joy, wellness, and spiritual fulfillment, hopeful for Ramadan to return in future years laden with prosperity and blessings for all.

The Publisher

46 Transforming Healthcare, a spotlight on ACIBADEM HEALTHCARE GROUP

66 'OR of the future' houses new tech to view the brain like never before

76 Accuhealth Offers a Personalized Approach to Chronic Care Management

ACIBADEM HEALTHCARE GROUP

46 Transforming Healthcare, a spotlight on ACIBADEM HEALTHCARE GROUP

48 ACIBADEM UNIVERSITY… Leading the way in higher education & healthcare in Türkiye

50 ACIBADEM LABMED... Türkiye’S FIRST ISO-15189 Accreditation Clinical Laboratory

52 Innovative Healthcare Solutions Redefining the Industry by ACIBADEM TECHNOLOGY

54 ACIBADEM PROJECT MANAGEMENT... Leading the Way in Healthcare Infrastructure Development

56 ACIBADEM APLUS... Introduces Revolutionary Catering and Cleaning Solutions

58 ACIBADEM MOBIL... Revolutionizes Home care with Innovative Services

NEWS

8 Oracle Receives Best in KLAS 2024 EMR Recognition for Middle East and Africa

44 ‘Shaping the Future of Healthcare’ Symposium Charts the Evolving Role of Clinical Leaders to Dynamic Healthcare Landscape

ARTICLES

62 "The Blockchain Health Revolution: Transforming Healthcare One Block at a Time" by Dr. Samer Ellahham

80 Redefining Women's Healthcare: A Glimpse into Our Gynecology Department's Dedication to Luxury, Safety, and Expertise Dr. Maysa Khadra Consultant IVF and OBG Head of

Department at Al-Ahli Hospital/Qatar

86 BD: ‘Beyond Everyday’: Specialist Infusion Management

106 Al-Ahli Hospital diagnoses digestive diseases using the smart capsule by Dr. Wissam Malki

MEDICAL TECH

76 Accuhealth Offers a Personalized Approach to Chronic Care Management

INTERVIEWS

36 Dr. Amal Khidir, MBBS, Associate Professor of Pediatrics at Weill Cornell Medicine-Qatar (WCM-Q)

70 Arnaud Teulet, International Sales Director of Lépine

72 Omar Riyal, Divisional Vice President at Abbott’s transfusion medicine business

MEDICAL INSTITUTIONS

64 'OR of the future' houses new tech to view the brain like never before provided by Uchicago Medicine

74 "Mazaya" Medical Company continues its journey of excellence and enhances its presence with agreements and awards

FEATURES

60 The Impact of AI on Medical Imaging and Patient Care

64 Congenital Heart Defects

82 Cancer Detection

96 The Pediatric Emergency Department

102 Making Life Easier and Smoother for Diabetic Patients

Oracle Receives Best in KLAS 2024 EMR Recognition for Middle East and Africa

Oracle has received the Best in KLAS award for acute care EMR (electronic medical records) in Middle East and Africa for the sixth consecutive year . The report highlights Oracle Health’s continued high customer engagement resulting from strategic partnerships and high-touch efforts in the region.

“Oracle is building an open and connected healthcare ecosystem with intelligent tools to modernize healthcare and help improve outcomes for patients,” said Akram Sami, Vice President and Managing Director, Oracle Health Middle East and Africa. “This recognition is a testament to our commitment to meet the evolving needs of providers and patients throughout the region.”

Oracle Health continues to partner with customers in the region to transform their operations from the bedside to the back office. Most recently, Burjeel Holdings PLC awarded Oracle Health an AED 125 million contract to implement a state-of-the-art electronic medical record ecosystem, making it one of the first regional healthcare providers to adopt and implement a new Oracle Health EMR solution

running on Oracle Cloud Infrastructure in the Oracle Cloud Dubai Region. Oracle Health is also collaborating with Emirates Health Services to advance clinical device integration, a process that employs the capabilities of Oracle Health’s EMRs to receive vital clinical information from patient medical devices with speed and precision. The 2024 Best in KLAS Report – Global Software determines its rankings from a combination of in-depth interviews and data points captured over the course of a year through a process of customer interviews. Rankings are a result of the feedback received from providers.

“Achieving best in KLAS year after year is a testament to the depth of our integrated, secure healthcare technology portfolio and commitment to working in partnership with our clients to help them transform how they do business for the betterment of their patients and staff,” said Seema Verma, Executive Vice President and General Manager, Oracle Health and Oracle Life Sciences. “Together with our regional clients, we are pushing the envelope of innovation to drive new advancements, while helping them improve and boost operational efficiency and financial governance.”

Mediclinic Welcare Hospital Opens its Renovated Emergency Department

MORACLE HEALTH HOLDS TOP SPOT FOR ACUTE CARE IN EMERGENCY MEDICAL RECORDS FOR THE SIXTH YEAR.

ediclinic Welcare Hospital has completed its renovation of the Emergency Department. With a focus on providing efficient and top-quality healthcare services, the hospital has made significant upgrades to enhance patient care and overall experience. The redesigned department is equipped with state-of-the-art facilities and cutting-edge technology, ensuring the highest standard of medical care for Dubai residents. With two separate entrances for walk-in patient and ambulance admissions, patients can easily access fast-track services further reducing waiting times and streamlining the emergency medical process.

"The renovation of our Emergency Department is a testament to our commitment to providing exceptional emergency healthcare services to our patients,” said Dr Mohammed AlAzzawi, Chief of Emergency Medicine at Mediclinic Welcare Hospital. “Our redesigned facilities and highly skilled staff will ensure that patients receive immediate attention and treatment in a comfortable and modern environment. “We value our patients’ time and recognise the need for prompt attention to both urgent and non-urgent cases. That's why we have introduced a Fast Track Area equipped with cutting-edge technology and a specialised team. This designated area is designed to efficiently manage patients, minimise waiting times and ensure that you receive the care you need when you need it.”

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Essenza 300 is a top-quality, smart hospital bed available as a universal low-height bed or Essenza 300 LT with bed-framed lateral tilt.

Jitka Stranska Managing Director of LINET MEA

“The fusion of hospital care and hotel services is increasingly evident. Prestigious hospitals not only pay attention to high-level medical standards but also to other aspects of hospitality, including, among others, top-quality interior design. We are delighted that our beds are once again bringing a new element: personalized room customization. Thanks to special technology, our new Essenza 300 bed offers a completely individual design to match the room concept or create pleasant healing environment.”

The University of Chicago Medicine Welcomes You to the Forefront

Where some of the greatest advances in medicine are hard at work for you.

The University of Chicago Medicine pioneers the kind of research that’s changing lives. It is home to the most advanced medical technology, and physicians who work at the forefront of their fields.

It is our mission to bring the forefront of medicine to the world through personalized international patient services and tailored global advisory and education programs.

Clinical Centers of Excellence

» Comprehensive Cancer Center

» Transplant Institute

» Heart & Vascular Center

» Neuroscience Center

» Digestive Diseases Center

» Orthopaedic Surgery

» Obstetrics & Gynecology

» Pediatrics

For more information, visit

UChicagoMedicine.org/global

100 Nobel Laureates, including 12 in Physiology or Medicine

Magnet Recognition for Excellence in Nursing & Patient Care

One of only 18 acute-care facilities nationwide to receive “A” grade in patient safety from Leapfrog Group for 24 consecutive periods as of November 2022

Ranked nationally in multiple adult and children’s specialties by U.S. News & World Report

GLOBAL EXECUTIVE PROGRAM

An Exclusive Opportunity for International Healthcare Leaders

May 13–17, 2024

The University of Chicago Medicine Welcomes You to the Forefront

This intensive educational opportunity is exclusively for international healthcare leaders who want to earn credits towards their FACHE®, experience the best learning that the US healthcare has to offer, and develop universal leadership skills from expert ACHE faculty.

Where some of the greatest advances in medicine are hard at work for you.

Chicago, IL

30 ACHE In-Person Education Credits

This dynamic professional development program provides participants with both high-quality, classroom-based instruction and on-site, experiential learning in a world-class hospital setting, at the University of Chicago Medicine.

The University of Chicago Medicine pioneers the kind of research that’s changing lives. It is home to the most advanced medical technology, and physicians who work at the forefront of their fields.

Register today to gain opportunities to collaborate with peers in small groups, earn In-Person Education credits and listen to engaging lectures from experienced executives on timely healthcare topics!

Participants will:

It is our mission to bring the forefront of medicine to the world through personalized international patient services and tailored global advisory and education programs.

100 Nobel Laureates, including 12 in Physiology or Medicine

Magnet Recognition for Excellence in Nursing & Patient Care

» Identify the skills necessary to work more effectively with board of directors and committees

Clinical Centers of Excellence

» Comprehensive Cancer Center

» Create professional development plans from individualized career assessments

» Transplant Institute

» Explore effective tactics for having difficult conversations with team members

» Heart & Vascular Center

» Neuroscience Center

» Learn how to leverage the key behaviors that influence change in teams and organizations

» Digestive Diseases Center

» Orthopaedic Surgery

One of only 18 acute-care facilities nationwide to receive “A” grade in patient safety from Leapfrog Group for 24 consecutive periods as of November 2022

» Discover innovative solutions from executive leadership panel discussions

» Obstetrics & Gynecology

» Pediatrics

The University of Chicago Medicine is one of America’s leading a cademic m edical institutions, comprising the Pritzker Sc hool o f M edicine, o ne of the top medical s c hools in the nation; the University of Chicago Biological Sciences Division, wh ich twelve Noble Prize w inners in physiology or m edicine have been affiliated w ith; and the University of C hicago Medical Center, which o perates four inpatient hospitals a nd 10 ambulatory facilities a round t h e C hicago a r e a

Ranked nationally in multiple adult and children’s specialties by U.S. News & World Report

For more information, visit

Early bird discounts available. Seats are limited.

UChicagoMedicine.org/global

Our clinical and administrative experts are committed to offering practical education and training programs customized to meet the specific needs of international healthcare organizations and professionals

Burjeel Medical City Showcases Innovation and Unveils Initiatives at Arab Health 2024

Burjeel Holdings, one of the leading private healthcare service providers in the MENA region, has made a significant impact at the Arab Health 2024 exhibition through its flagship facility, Burjeel Medical City (BMC). The event served as a platform to highlight two crucial initiatives launched, emphasizing BMC’s commitment to excellence in healthcare.

The first initiative, titled ‘Safeguarding Your Health at the World’s Safest City,’ showcased BMC as a global destination for cutting-edge medical services. By spotlighting BMC’s capabilities on an international stage, Burjeel Holdings underscored its commitment to providing world-class healthcare solutions to patients from around the world.

The second initiative, the ‘Ring for Life’ campaign, became a symbol of hope for cancer patients, signaling the latest developments and advanced care in oncology. The highlight of this campaign was the ceremonial ringing of the bell by renowned Arab singer and cancer survivor Elissa at the BMC booth. Elissa’s triumphant battle against cancer served as an inspiration to those facing similar challenges, reinforcing the message of resilience and progress in oncology care. The ‘Ring for Life’ initiative garnered significant attention and participation from visitors, creating a poignant display of solidarity and hope.

THE FIRST INITIATIVE, TITLED ‘SAFEGUARDING YOUR HEALTH AT THE WORLD’S SAFEST CITY,’ SHOWCASED BMC AS A GLOBAL DESTINATION FOR CUTTING-EDGE MEDICAL SERVICES. BY SPOTLIGHTING BMC’S CAPABILITIES ON AN INTERNATIONAL STAGE, BURJEEL HOLDINGS UNDERSCORED ITS COMMITMENT TO PROVIDING WORLDCLASS HEALTHCARE SOLUTIONS TO PATIENTS FROM AROUND THE WORLD.

The atmosphere at the BMC booth was nothing short of extraordinary throughout the event, with distinguished guests and visitors actively engaging in the ‘Ring for Life’ initiative. His Excellency Abdulrahman bin Mohamed Al Owais, UAE Minister of Health and Prevention, His Excellency Mansoor Al Mansoori, Chairman of the Department of Health – Abu Dhabi, and His Excellency Awadh Seghayer Al Ketbi, Director General of Dubai Health Authority visited the booth and joined the initiative. Government officials including His Excellency Khaled Abdel Ghaffar, the Egyptian Minister of Health and Population, and industry leaders visited the booth to discuss various initiatives and explore potential collaborations.

The BMC booth also served as a dynamic hub for the next generation of healthcare professionals. Dr. Shamsheer Vayalil, Founder and Chairman of Burjeel Holdings, engaged with students from Khalifa University, imparting valuable insights and inspiring confidence in these future healthcare professionals. Furthermore, the unveiling of the book ‘Cancer Care in the United Arab Emirates,’ edited by Prof. Humaid Al Shamsi, Director of Oncology at Burjeel Holdings, highlighted Burjeel Holdings’ commitment to pioneering medical research and advancements in oncology care. The book, featuring contributions from doctors within the Burjeel Holdings network, reflects the organization’s dedication to sharing expertise and knowledge to improve patient outcomes.

Furthermore, experts shared insights and learnings while marking the milestone of completing 100 successful bone marrow transplants. BMC conducted the first pediatric bone marrow transplant in the UAE in 2022.

Burjeel Holdings’ participation in Arab Health 2024 through BMC exemplified innovation, compassion, and excellence in healthcare. With groundbreaking initiatives, collaborative partnerships, and a relentless commitment to patient care, BMC continues to redefine the future of healthcare, offering hope and healing to individuals worldwide.

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Avalon Pharmaceuticals Announces International Partnership with City Pharmacy

Avalon Pharmaceuticals, one of the fastest growing home-grown pharmaceutical companies in Saudi Arabia, has announced plans to partner with regional leader City Pharmacy. Originating in Saudi Arabia, Avalon Pharmaceuticals has a storied 25-year history within the Kingdom, marked by its pursuit of excellence in the health, beauty and prescription medicine sectors. Avalon has plans to initiate several key partnerships across the industry and will begin this new phase by forming a strategic partnership with City Pharmacy. The partnership will allow Avalon to widen its reach across the GCC by offering Avalon’s products to City Pharmacy’s retail locations across the UAE. Avalon has recently announced plans for several new international partnerships which introduce a new strategy of acceleration, catalyzation and expansion.

Mohamed Maher Alghannam, Managing Director & CEO of Avalon Pharma, said: “We have found great success in the Kingdom and have set our sights on a multi-pronged international expansion plan. Partnering with City Pharmacy is a major step towards realizing our global ambitions. Our goal is to increase total exports from 10% to 30% by 2030. City Pharmacy has done extremely well in the UAE and is the ideal partner to introduce our products across the Emirates. We’ve recently opened a regional office in Dubai which will help make this partner-

SAUDI PHARMACEUTICAL POWERHOUSE AVALON PHARMA IS WIDENING ITS INTERNATIONAL FOOTPRINT WITH A STRATEGIC PARTNERSHIP WITH UAE PHARMACEUTICAL LEADER CITY PHARMACY

ship a major triumph for Avalon, City Pharmacy and our customer base.”

City Pharmacy, the largest pharmaceutical distributor in the UAE, has a rich history across the Emirates. Founded in 1967, City Pharmacy is the leading pharmaceutical, healthcare and medical equipment distributor in the UAE, distributing a wide range of products to consumers. Beyond the UAE, Avalon has plans to further its plans of international expansion by targeting emerging markets such as Libya, Sudan, Uganda and Egypt with additional focus placed on exploring markets in North Africa and East Asia by championing the “Made in Saudi” tagline affixed to its products, a popular hallmark within key international markets.

Al Ghannam, also said: “We have made numerous strides in the UAE in recent years and our partnership with City Pharmacy will further these aims. Avalon Pharma has strengthened the global awareness of products ‘Made in Saudi’, offering new opportunities in the GCC and beyond. We are well positioned to continue our expansion within the GCC and across several new markets.”

Avalon Pharma is best known for its wide-ranging products which include cosmeceuticals, oral hygiene products, sanitizers, and herbal medicine. The company produces a broad portfolio of merchandise with plans to add increased stock to its portfolio.

Planetree’s Exclusive Person-Centered Excellence Program Takes Center Stage at Arab Health

Planetree, the global leader in personcentered care, showcased its recently updated Certification standards at the Arab Health Expo 2024 in Dubai, UAE. The Expo, attended by more than 3,600 healthcare industry professionals, featured the newly designed Planetree exhibit, providing visitors with information about the organization’s consulting, training, and certification services. Reflecting on their attendance at the Expo, Planetree’s Director of Global Services, Mandy Kilmartin, said “This year’s presence at Arab Health provided a unique opportunity to connect with industry and government leaders, clients, and members, who are more frequently turning to Planetree for guidance in improving the care experience.”

Planetree currently offers the world’s only program for achieving Certification for Excellence in Person-Centered Care®. Rooted in Planetree’s exclusive research and evidence-based framework, the Certification program is endorsed by the Joint Commission International (JCI) and recognized by the International Society for Quality in Health Care’s External Evaluation Association (ISQua EEA). To date, Planetree certifies more than 180 organizations in 13 countries and utilizes its Certification program to guide implementation of person-centered cultural transformation in over 800+ organizations worldwide spanning the continuum of care.

“Healthcare organizations around the world turn to Planetree’s Person-Centered Care Certification® standards as the benchmark of excellence and the framework for translating PCC concepts into reality,” said Michael Giuliano, Planetree’s President. “Our successful engagements at Arab Health 2024 are an important part of Planetree’s ongoing mission to lead transformative improvements in personcentered care,” Mr. Giuliano said.

Following the close of the Arab Health Expo, Planetree was hosted by Fakeeh

ROOTED IN PLANETREE’S EXCLUSIVE RESEARCH AND EVIDENCEBASED FRAMEWORK, THE CERTIFICATION PROGRAM IS ENDORSED BY THE JOINT COMMISSION INTERNATIONAL (JCI) AND RECOGNIZED BY THE INTERNATIONAL SOCIETY FOR QUALITY IN HEALTH CARE’S EXTERNAL EVALUATION ASSOCIATION (ISQUA EEA).

University Hospital (FUH), the UAE's only Gold certified Planetree organization, to provide a unique learning experience to regional guests. The “Planetree in Action: A Masterclass for Achieving Excellence in Person-Centered Care” offered participants an exclusive “inside look" at Planetree's standards in action. The FUH leadership team provided insights into both the process and benefits of implementing Planetree’s evidence-based standards across the organization. They shared personal experiences, motivations, and what they believe are the tangible results of building a culture of personcentered excellence. Masterclass participants also benefited from engaging with Planetree's leading Certification expert, Christy Davies, Director of Certification, on the requirements and process for attaining Certification for Excellence in Person-Centered Care.

INSIGHTERS® VIDEO LARYNGOSCOPE

*Not all airways are created equal.* Up to 8.5% of patients can experience difficulty getting a breathing tube in place during regular laryngoscopy. In rare cases (about 1 in 2,000), it might even fail completely. The good news? Video laryngoscopes, like Insighters® device, can help doctors see the airway better. This can lead to smoother intubation, less damage to the airway, and fewer failed attempts.

Here's what makes Insighters® so versatile: It has a high-resolution camera for a crystal-

clear and precise view of the airway, singleuse blades in various sizes to fit different patients, and a compact, portable design for use anywhere in any clinical setting.

Moreover, it seamlessly connects to various monitors, from large screens to tablets, allowing for easy sharing and recording to improve teamwork and training through realtime high resolution image and video sharing; and therefore achieve optimal intubation efficiency and success.

Dr. Yousif Al Serkal: Emirati Doctors' Success Reflects Their Proficiency and Expertise

H.E. Dr. Yousif Mohammed Al Serkal, Director-General of Emirates Health Services (EHS), extended congratulations to Emirati doctors on the occasion of Emirati Doctor's Day, celebrated annually on March 11 in the UAE. He praised their efforts and contributions to advancing the healthcare sector in the country, noting that the wise leadership has been keen on human development and investing in their capabilities, believing in the importance of establishing an integrated healthcare system rich in competencies, potentials, readiness, and excellence within a motivating and supportive environment for national healthcare cadres. He affirmed that the achievements of Emirati doctors in recent years reflect their high efficiency and experience, highlighting their ability to provide high-quality healthcare to both citizens and residents alike.

H.E. added that Emirates Health Services has been keen on supporting and developing national medical cadres through specialized training programs, as well as enhancing their medical capabilities and skills through the adoption of the Visiting Consultants Program aimed

at exchanging experiences and expertise. He explained that the importance of these initiatives lies in achieving the targeted quality of healthcare and aligns with "We the UAE 2031" vision and the UAE Centennial 2071, where EHS seeks to enhance the healthcare sector and improve the quality of medical services provided to meet the aspirations of citizens and residents, thus enhancing the UAE's regional and global standing.

H.E. emphasized that the EHS has placed a strong emphasis on supporting and advancing the skills of national medical professionals through specialized training programs. Additionally, they have bolstered their medical capabilities and expertise by introducing a visiting doctors program designed to foster the exchange of knowledge and experiences. This strategic direction aims to achieve healthcare quality goals in line with the vision of "We the UAE 2031" and the UAE Centennial 2071. The EHS is committed to enhancing the healthcare sector, improving the quality of medical services, meeting the needs of citizens and residents, and elevating the UAE's regional and global reputation.

EMIRATES HEALTH SERVICES HAS BEEN KEEN ON SUPPORTING AND DEVELOPING NATIONAL MEDICAL CADRES THROUGH SPECIALIZED TRAINING PROGRAMS, AS WELL AS ENHANCING THEIR MEDICAL CAPABILITIES AND SKILLS THROUGH THE ADOPTION OF THE VISITING CONSULTANTS PROGRAM AIMED AT EXCHANGING EXPERIENCES AND EXPERTISE

Dr. Yousif Al Serkal

At Opening of Arab Health 2024, U.S. U.S. Health and Medical Suppliers, Service Providers See Growth Opportunities Throughout The MENA Region

The United States hit the ground running at Arab Health 2024 with some 230 exhibitors looking to build on the nation’s well-established footprint in the booming health and medical markets of the Middle East and North Africa (MENA) region.

Driven by growing populations, demographic shifts, and a corresponding rise in chronic diseases such as diabetes, heart disease, and depression, the value of the healthcare market in the U.A.E. alone in 2022 totaled $1.83 billion and is predicted to nearly double by 2030 to $3.59 billion, according to the U.S.-UAE Business Council. The strong U.S. showing at Arab Health underscores America’s long-standing commitment to helping its partners throughout the region meet this unprecedented demand for quality hospitals, clinics, equipment, and healthcare professionals. The centerpiece of the U.S. national presence at the show is the USA Partnership Pavilion, organized for the 29th consecutive edition by Kallman Worldwide, Inc., in coordination with government agencies, including the U.S. Departments of Commerce and State, and industry leaders including AmCham Dubai and the U.S-UAE Business Council. The Pavilion roster includes 41 first time exhibitors at the show and 32 that are new to the market. A total of 27 states are represented, including nine stand-alone state pavilions — California, Colorado, Florida, Georgia, Illinois, Maryland, North Carolina, New York, and Ohio — within the larger U.S. space. All are looking to generate new business and create jobs by growing exports, expanding their in-region footprint, and/or recruiting overseas partners to establish or participate in stateside operations.

“Now more than ever, success in international trade comes from partnership and teamwork. The USA Partnership Pavilion sharpens our focus on advancing America’s leadership in healthcare and medicine to help improve patient outcomes

THE PAVILION IS AMERICA’S HEADQUARTERS ON-SITE, OCCUPYING AN AREA OF MORE THAN 4000 SQUARE METERS, IT IS A HIGHPROFILE SHOWCASE FOR U.S. EXHIBITORS TO MAXIMIZE THEIR SUCCESS AT THE EVENT, AND A FORUM FOR ALL TO SHARE IDEAS AND INSIGHTS.

and quality of life around the world,” said Kallman Worldwide President and CEO, Tom Kallman. “From world-class hospitals to equipment, instrument, and device manufacturers, and even decontamination and materials management services, many of our exhibitors already have significant partnerships and operations in the UAE and MENA region. In the years to come, many more will.”

In virtually all sectors represented at Arab Health 2024, the role of artificial intelligence as an accelerator of innovation in healthcare and medicine figured prominently in presentations and conversations on the show’s opening day. Speaking on a panel discussion at AmCham Dubai’s “Arab Health Kickoff Breakfast,” Dr. Tao Xu, Associate Professor, Mount Sinai Health System, helped set the stage with this prescription for clinical applications of AI innovations.

“The world of AI and digital enhancement has accelerated its presence in clinical medicine,” said Dr. Xu, “and there is a wealth of opportunities to smartly but carefully integrate the two to improve patient outcomes as well as provider and patient experiences.”

NEW IMAGING HORIZONS.

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ULTRA-DETAILED MULTI-DIAGNOSTICS

Localised analysis over the entire body. Ray2D and 3D imaging up to 90 µm, also with radiocontrast agent. Artifact reduction and movement analysis using CineX and Cine-Scout. The eXtra Functions protocol extends the field of view longitudinally to analyse anatomical structures such as the spine and limbs.

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MAXIMISING PATIENT CARE

The patient lies comfortably on the table and X-ray doses are always proportioned to the patient’s build and the examination type thanks to SafeBeamtm technology.

Dibba Hospital Earns "Baby-Friendly Hospital" Accreditation from WHO and UNICEF

Emirates Health Services (EHS) facilities achieved a new significant milestone with Dibba Hospital being honored as a "Baby-Friendly Hospital." The hospital, one of EHS’s facilities, successfully passed the policy implementation test and adhered to both international and local codes completely. It has succeeded in providing high-quality healthcare for children and delivering superior medical services.

This achievement was earned through the hospital's exceptional delivery of quality healthcare services, supported by the dedicated efforts of its administrative, medical, and nursing staff. Following a rigorous three-day evaluation by the WHO and UNICEF, through the Ministry of Health and Prevention (MoHAP) National Committee for Motherhood and Childhood, the hospital successfully met the criteria for the "Baby-Friendly Hospital" title. This achievement reflects the hospital's commitment to promoting breastfeeding through the adoption of a breastfeeding policy, providing staff training, and creating a supportive environment for mothers to continue breastfeeding, along with providing educational sessions for mothers during prenatal and postnatal visits to increase knowledge and awareness. The "Baby-Friendly Hospital" initiative is based on adopting the Ten Steps to Successful Breastfeeding policy.

H.E. Dr. Essam Al Zarooni, Acting Executive Director of Clinical Services Sector at EHS, highlighted the importance of this title for EHS’ facilities. He emphasized how it symbolizes EHS’ unwavering dedication to delivering top-tier healthcare to the community, with a special focus on the health and well-being of children. Dr. Al Zarooni highlighted that attaining the "Baby-Friendly Hospital" designation showcases the hospital's commitment to upholding global standards in providing cutting-edge and specialized medical services for children.

Wedad Mohammed Al Fard, the Director of Dibba Hospital, expressed her pride in this

accomplishment, which solidifies the hospital's position as a distinguished medical facility both locally and globally. She emphasized that this success reflects the unwavering dedication and positive teamwork of the hospital staff, who consistently strive to improve the quality of healthcare services and create a safe, comfortable environment for children and their families. Wedad commended the combined efforts of the administrative, medical, nursing, and technical staff at the hospital.

The internationally acclaimed "Baby-Friendly" initiative by both the World Health Organization and UNICEF, strives to safeguard and enhance the health of infants and young children. It centers on addressing the needs of mothers and their newborns to facilitate successful breastfeeding as the optimal beginning to life. The initiative's program encompasses promoting, safeguarding, and improving the practice of breastfeeding to support the health of both the child and the mother.

This achievement is a result of EHS’ directives, plans, and strategies aimed at providing excellent care for women's and children's health. This includes implementing quality policies and programs, training and preparing healthcare professionals involved in maternal and child health, raising awareness about global trends and best practices, and equipping them with the necessary skills to deliver quality healthcare for children.

H.E. Dr. Essam Al Zarooni

Wedad Mohammed Al Fard

Liquid biopsy in breast cancer – Less invasion more precision

Plasma-SeqSensei™

Liquid biopsy in breast cancer – Less invasion more precision

Plasma-SeqSensei™

The Plasma-SeqSensei Breast Cancer IVD Kit is an NGSbased liquid biopsy assay that focuses on highly sensitive detection of clinically relevant mutations in TP53, ESR1, PIK3CA, AKT1 and ERBB2 from blood plasma.

Learn more about the unique advantages of Plasma-SeqSensei technology

The Plasma-SeqSensei Breast Cancer IVD Kit is an NGSbased liquid biopsy assay that focuses on highly sensitive detection of clinically relevant mutations in TP53, ESR1, PIK3CA, AKT1 and ERBB2 from blood plasma.

High sensitivity at low MAFs

Learn more about the unique advantages of Plasma-SeqSensei technology

Down to 0.06% - 0.07% Mutant Allele Fractions.

High sensitivity at low MAFs

Down to 0.06% - 0.07% Mutant Allele Fractions.

Absolute quantification

Short and standardised workflow

From cfDNA samples to results in two days.

Short and standardised workflow

From cfDNA samples to results in two days.

Data analysis and reporting made easy Generate report designed for clinicians with just a few clicks.

Absolute quantification

Meaningful comparison of ctDNA levels per millilitre of plasma.

Expert voices

Meaningful comparison of ctDNA levels per millilitre of plasma.

Data analysis and reporting made easy

Generate report designed for clinicians with just a few clicks.

Expert voices

‘We know that tissue samples cannot be taken regularly, but liquid biopsy is easy to take, it is simply a sample of blood. And it gives you real-time information.’

‘Even low levels of ctDNA could have given an indication of the coming progression in the follow-up.’

‘There is much more diagnostic power in the absolute quantification.’

Dr Bhuwnesh Agrawal Member of The Supervisory Board Sysmex Inostics and MD, Germany

‘We know that tissue samples cannot be taken regularly, but liquid biopsy is easy to take, it is simply a sample of blood. And it gives you real-time information.’

Dr Bhuwnesh Agrawal

Member of The Supervisory Board

Sysmex Inostics and MD, Germany

‘Even low levels of ctDNA could have given an indication of the coming progression in the follow-up.’

‘There is much more diagnostic power in the absolute quantification.’

Prof. Christopher Gebhardt UKE Hamburg, Germany

Prof. Christopher Gebhardt

UKE Hamburg, Germany

Prof. Geert A. Martens AZ Delta General Hospital, Belgium

Prof. Geert A. Martens

AZ Delta General Hospital, Belgium

What is mixed methods research and why is it a valuable approach for clinical researchers?

Traditionally, physicians have been more inclined towards quantitative research and less interested in quantitative approaches. This is perhaps because practitioners of the scientific approach have traditionally felt more comfortable with the certainty of data that are presented as numbers than those which are presented in words, which are more difficult to interpret and draw conclusions from. Of course, there are many merits to quantitative approaches, but this also means that valuable and important qualitative data has frequently been excluded from research projects. Mixed methods approaches, which should be

Dr. Amal Khidir, MBBS

Associate Professor of Pediatrics at Weill Cornell Medicine-Qatar (WCM-Q)

"Mixed methods approaches can give researchers a deeper understanding of the subject they are investigating"

Dr. Amal Khidir is Associate Professor of Pediatrics and Vice Chair of the Institutional Review Board (IRB) at WCM-Q. An American Board-certified physician, she practices pediatrics at Sidra Medicine and Hamad Medical Corporation (HMC), where she also supervises medical students and residents. The research interests of Dr. Khidir, who joined WCM-Q in 206, focus on medical education, professionalism, faculty development, health promotion, and cultural competency. She also has a strong interest in the application of mixed methods approaches in clinical research, an area in which she has shared her expertise with fellow healthcare professionals through a series of interactive workshops developed in collaboration with the University of Michigan. Under the auspices of WCMQ’s Division of Continuing Professional Development, Dr. Khidir will co-direct another installment of the three-day virtual workshop, titled "Learning and Applying Essentials of Mixed Methods Research (MMR)", on May 24, 25 & 31, 2024. Dr. Khidir spoke with "Hospitals" magazine to discuss the strengths of mixed methods research as a tool for clinical researchers.

conducted in a systematic way, can enrich the evidence and give researchers a deeper and more comprehensive understanding of the subject they are investigating.

Please tell us a little about the different types of mixed methods research. There are three main kinds of mixed methods research designs, these being convergent, exploratory sequential, and explanatory sequential. In the convergent model, both quantitative and qualitative data are collected simultaneously, analyzed and the two sets of data are then integrated by the researchers to try to answer their research question. In projects with an exploratory sequential design, qualitative data is collected first, through

"THE COURSE IS VERY ACCESSIBLE AS IT IS BEING OFFERED ONLINE AS A VIRTUAL WORKSHOP, SO HEALTHCARE PROFESSIONALS FROM ALL OVER THE REGION AND BEYOND CAN TAKE PART VERY EASILY."

interviews with patients, for example, and this will inform the collection of the quantitative data, which could be through a survey. In the explanatory approach, which is also sequential, you do quantitative research first and then you follow that up with qualitative research to try to explain and go in-depth so that you can gain a better understanding of the findings.

How is mixed methods research applicable to clinical research projects?

Mixed methods approaches have many applications in clinical research because the end goal in medicine is to provide quality care for patients, so it is important to discover, for example, how patients experience care—mixed methods research is very good for this. Using mixed methods approaches we can collect quantitative data about how many patients received a particular kind of treatment, what percentage saw an improvement in their symptoms, how many made a full recovery, how many completed the course of treatment and how many did not, and so on and so forth. This is all useful data, but if we want to learn more about the data and extract more useful and meaningful conclusions, we can incorporate qualitative research. For example, we can create a questionnaire or interview and gather their impressions or opinions, such as, did the patients feel they received adequate information about their condition and the treatment and how was that information delivered, did they have difficulty navigating the healthcare system, how did they navigate the system, were they successful at navigating the system or not, what factors helped or prevented them from completing the course of treatment, and so on. Clearly these impressions are useful because they can help clinicians implement changes that improve patient outcomes. So, with mixed methods approaches we can really enrich the quantitative data findings by explaining them with qualitative data findings.

How can healthcare professionals with an interest in mixed methods benefit from the training workshop you are running?

The course is very accessible as it is being offered online as a virtual workshop, so healthcare professionals from all over the region and beyond can take part very easily. The workshop lasts for three days and we have designed it to be very hands-on and interactive.

The course involves didactic sessions, working sessions where they get to work very closely with a mixed methods expert, small group sessions, and sessions in which we review and analyze published articles.

The attendees will have brief didactic sessions explaining the mixed methods concepts, followed by several hands-on activities for application of the concepts over two days. Then we have a gap of a week, during which the participants digest what they have learned and review and evaluate a couple of articles. They return for the final day and have smallgroup hands-on sessions in which they apply the concepts in the reviewed articles and actually work on how to prepare a response or feedback as a reviewer. The course is presented and facilitated by Dr. Timothy Guetterman, Dr. Sergi Fàbreques, Dr. Meshari Alwashmi, myself, Dr. Phyllis Navti, Ms. Maha Elnashar, and Ms. Huda Abdelrahim, all of whom have extensive experience and expertise in the subject matter at hand.

By the end of the workshop, participants will have gained a very firm grasp of mixed methods research concepts, but they will also have an idea on what reviewers are looking for and how they may share feedback. The course has been developed in collaboration with experts from the University of Michigan, which is one of the leading institutions in the area of mixed methods research. We have offered the workshop on two previous occasions in a different format where attendees have made a lot of progress on their own personal research

"THERE ARE THREE MAIN KINDS OF MIXED METHODS RESEARCH DESIGNS, THESE BEING CONVERGENT, EXPLORATORY SEQUENTIAL, AND EXPLANATORY SEQUENTIAL. IN THE CONVERGENT MODEL, BOTH QUANTITATIVE AND QUALITATIVE DATA ARE COLLECTED SIMULTANEOUSLY, ANALYZED AND THE TWO SETS OF DATA ARE THEN INTEGRATED BY THE RESEARCHERS TO TRY TO ANSWER THEIR RESEARCH QUESTION."

projects, to the point that they may be ready to submit it, either for grant or for approval.

That was excellent, but this time that is not the objective. Instead, this time we will be aiming more to provide the mixed methods research knowledge and skills to enable the participants to independently design their own mixed methods-based studies and learn what the reviewers are looking for. We have received tremendously positive feedback for this course

so far, so we are hopeful that the forthcoming edition will be very successful and will help provide a very significant boost for mixed methods research in the region.

For more information and to register for the workshop, visit the website of the Division of Continuing Professional Development at WCM-Q: https://qatar-weill.cornell.edu/ continuing-professional-development

"THE COURSE HAS BEEN DEVELOPED IN COLLABORATION WITH EXPERTS FROM THE UNIVERSITY OF MICHIGAN."

GE HealthCare equips Saudi Arabia’s Dr. Sulaiman Al-Habib Medical Group with advanced digital healthcare tech solutions

In line with its commitment to advancing healthcare delivery in Saudi Arabia, GE HealthCare, a leading global medical technology and digital solutions innovator, is equipping all hospitals and medical centers under the Dr. Sulaiman Al-Habib Medical Services Group (HMG) with a comprehensive range of Imaging, Ultrasound and Patient Care Solutions to help clinicians improve patient outcomes and provide high-quality, seamless, and optimized care.

In a new collaboration with HMG, one of the largest and fastest growing hospital chains in Saudi Arabia and the region, thirteen hospitals and eight medical centers including two new state-of-the-art hospitals will be equipped with reliable and robust imaging technology, diagnostic cardiology and monitoring solutions, and maternal-infant care products.

Most of the advanced imaging technology solutions, including two MRI SIGNA Voyager, two Revolution Apex Elite CT, four C-arms, two BMD, and the first Discovery MI 6 ring PET/CT in Saudi Arabia, will be installed at the future 330-bed West Jeddah Hospital and the 500bed North Riyadh Hospital, the largest private hospital to be commissioned in Saudi Arabia.

GE HealthCare will also equip the two new facilities with a wide range of Patient Care Solutions innovations to assist clinicians, especially during surgical and procedural care, and to monitor patients easily and efficiently.

This includes the deployment of GE HealthCare’s Portrait Mobile, a wearable monitoring solution for real-time personalized view of the patient, at 80 hubs located across eight hospitals, including both existing and new facilities under HMG.

Commenting on the milestone achievement, Mohammad El Khoury, General Manager Saudi Arabia, GE HealthCare, said: “Under our longstanding collaboration with Dr. Sulaiman Al-Habib Medical Services Group, GE Health-

GE HEALTHCARE AND HMG AFFIRM

THE NEED FOR STRONG REGIONAL COLLABORATIONS

TO ADVANCE

THE KINGDOM’S HEALTHCARE

LANDSCAPE AND ACCELERATE

THE RATE OF INNOVATION

TO PROVIDE AN INTEGRATED CONTINUUM OF CARE IN LINE WITH THE GOALS OF SAUDI VISION 2030

Care is honored to bring a suite of advanced healthcare technology and monitoring solutions across the hospital network in Saudi Arabia to enable clinicians to improve patient care. This reflects our shared commitment to transforming healthcare practices in the Kingdom in line with the Vision 2030 goals. By co-creating innovative programs and delivering specialized tools and care solutions, we are proud to be part of HMG's journey to continually refine and enhance their operational workflows and set new standards for patient-centric care.”

Faisal Al-Nassar, Chief Executive Officer, Dr. Sulaiman Al-Habib Medical Services Group, said:

“Under the new collaboration with GE HealthCare, we aim to bring advanced technology that plays an increasing role in delivering the optimum care to our patients. Raising the standards of care and delivering best-in-class healthcare services to greater numbers of people across the Kingdom is the number one priority to HMG. Our investment in the comprehensive range of new diagnostic and monitoring equipment will strengthen operational efficiencies across our medical facilities and accelerate the shift to a more convenient and accessible delivery of care”.

What We Do

With a vast and diverse portfolio, Pharmatrade offers over 5000 high-quality products. These encompass a wide array of medical and pharmaceutical supplies, catering to various healthcare needs. Pharmatrade's product range is carefully curated to meet the requirements of both the Government and Private sectors in the UAE.

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5

LAU Medical Center-Rizk Hospital Empowers Community Health on World Obesity Awareness Day

The Lebanese American University Medical Center-Rizk Hospital proudly hosted an event on the occasion of World Obesity Awareness Day on the 4th of March.

The event aimed to address the critical issues of obesity, defined as abnormal or excessive fat accumulation that lead to health risks. A team of professionals from the Endocrinology department at LAU Medical Center-Rizk Hospital conducted Body Mass Index (BMI) tests, Ankle-Brachial Index screenings, InBody270 machine analyses, and personalized health recommendations free of charge. The results were also based off of each individual's weight, height, and questionnaire responses. This empowered participants to make informed decisions regarding their eating and lifestyle habits.

The event saw a significant turnout with more than 100 attendees. The level of engagement was impressive, confirming that people have a strong interest to prioritize health and address obesity. To symbolize the importance of cultivating healthy routines, participants completing the BMI test and questionnaire received a healthy snack as a start to their healthy journey. This not only highlighted the significance of balanced nutrition but also conveyed LAU Medical Center-Rizk Hospital's commitment to fostering a healthier community.

TO

THE

SYMBOLIZE

IMPORTANCE OF CULTIVATING HEALTHY ROUTINES, PARTICIPANTS COMPLETING THE BMI TEST AND QUESTIONNAIRE

RECEIVED A HEALTHY SNACK AS A START TO THEIR HEALTHY JOURNEY.

In addition to the health assessments, attendees left the event with knowledge and practical advice. An informative flyer, distributed upon completion of the questionnaire, contained valuable tips, resources, and guidance on maintaining a healthy weight and lifestyle.

“We are delighted by the positive response and engagement from the community. LAU Medical Center-Rizk Hospital remains dedicated to proactive healthcare measures. By providing individuals with the knowledge they need, we believe we have contributed to the ongoing global effort to combat obesity and promote overall health” said Dr. Kamal Hirbli, Clinical Associate Professor and Head of the Endocrinology Department, at the Lebanese American University Gilbert and Rose-Marie Chagoury School of Medicine.

Sami Rizk, LAU Medical Center-Rizk Hospital's CEO, reinforced this commitment by saying: "The success of the World Obesity Awareness Day reflects LAU Medical Center-Rizk Hospital’s dedication to making a lasting impact of healing with compassion."

LAU Medical Center-Rizk Hospital is unwavering in its commitment to spearheading proactive healthcare initiatives, nurturing a healthier community for a better tomorrow.

‘Shaping the Future of Healthcare’ Symposium Charts the Evolving Role of Clinical Leaders to Dynamic Healthcare Landscape

The ever-evolving role of clinical leaders was analyzed and discussed as healthcare leaders came together for a special 'Shaping the Future of Healthcare’ Symposium, organized by Dubai Healthcare City Authority (DHCA), the governing body of Dubai Healthcare City (DHCC) free zone, and RCSI University of Medicine and Health Sciences.

Held at DHCC Phase 2 Promenade in Al Jaddaf, the symposium provided a platform for insightful discussions on the ‘Evolving Role of Clinical Leaders in a Dynamic Landscape.’ Chaired by Dr. Colm Foster, Director of Academic Programs, RCSI Graduate School of Healthcare Management, the panel discussion saw the participation of UAE health

authorities, industry leaders and clinical experts gathered to debate key topics on the role of clinical leaders to suit an increasingly dynamic landscape, including key attributes needed to meet population growth and changing patient demands, the role of leaders in retaining and attracting talent and the requirement for them to acquire greater financial acumen.

A high-calibre panel of industry leaders delved into challenges facing the sector, unpacked opportunities and looked ahead to the future of healthcare. The panellists were Dr. Ibtesam AlBastaki, Director of Partnerships and PPP, Dubai Health Authority; Mr. Jaffar Bin Jaffar, Director of Property and Operations, Dubai Healthcare City Authority; Dr. Seema

THE SYMPOSIUM GATHERED INDUSTRY FIGURES TO DISCUSS CHALLENGES, OPPORTUNITIES AND SET THE COURSE FOR A SUCCESSFUL HEALTHCARE SECTOR.

Nour, Cardiology Consultant, Sheikh Shakhbout Medical City; Dr. Sumaya Mohamed Abbas, Director of Nursing Department, EHS; Head of the National Committee for Nursing and Midwifery Affairs, MOHAP; President of Emirates Nursing Association; Dr. Ameera Al Afeefi, Senior Specialist Outreach and Relations, Health Workforce Planning Division, Department of Health - Abu Dhabi; and Dr. Kristina Brown, Program Director, RCSI Graduate School of Healthcare Management.

Allae Almanini, Chief Financial Officer, Dubai Healthcare City Authority, said: “As Dubai’s healthcare and wellness destination and in line with our goal to enhance healthcare delivery in the UAE and beyond, we have a responsibility to bring together industry leaders periodically to share knowledge, insight and solutions to meet the challenges of a rapidly evolving healthcare sector". “We are grateful for the contribution of our strategic partner RCSI University of Medicine and Health Sciences in bringing together this symposium and the continued efforts to foster a collaborative environment for sharing ideas and best practices. As the healthcare landscape continues to evolve, we remain committed to providing our community with platforms and pathways to foster professional development and opportunities for knowledge sharing, creating synergies and partnerships to grow our ecosystem.”

Eunan Friel, Managing Director of Healthcare Management and a Member of the

RCSI Senior Management Team, said: “We have a long-standing strategic relationship with DHCA, and our joint efforts are going from strength to strength, as highlighted by this symposium. The main takeaway today is recognizing that clinical leaders are not only healthcare professionals with senior leadership responsibilities, but rather that all healthcare professionals, whether clinical or non-clinical, have a critical role in shaping the future of healthcare in the UAE.

“We are very proud to witness the impact our alumni and strategic partners are driving in the UAE and remain committed to the region in supporting healthcare professionals, through high-quality education and continuing professional development programs.”

In addition to charting a blueprint for the role of clinical leaders, the event provided a unique networking opportunity for industry professionals and facilitated the establishment of connections that contribute to the ongoing advancements in healthcare leadership and education ultimately supporting patient care.

The 'Shaping the Future of Healthcare’ Symposium underlines the strength and collaborative efforts of the partnership between DHCC and RCSI University of Medicine and Health Sciences, which dates back more than a decade through the establishment of its regional headquarters RCSI Dubai in DHCC. The entities signed an MoU in 2018 to foster advancement in healthcare training, education and research supported by the ongoing work of RCSI Dubai as an active member of the DHCC community.

THE EVENT HOSTED BY DUBAI HEALTHCARE CITY AUTHORITY AND RCSI UNIVERSITY OF MEDICINE AND HEALTH SCIENCES ANALYZES KEY ATTRIBUTES

CLINICAL LEADERS NEED TO SHAPE

THE FUTURE OF HEALTHCARE AND MEET CHANGING PATIENT NEEDS

Transforming Healthcare, a spotlight on ACIBADEM HEALTHCARE GROUP

The Leading Health Services Provider in Türkiye

In the dynamic landscape of healthcare, one name stands out for its commitment to excellence, innovation, and patient-centric care: ACIBADEM HEALTHCARE GROUP. With a rich history spanning over three decades, ACIBADEM has emerged as a pioneering force in Türkiye's medical sector and has garnered international recognition for its world-class healthcare services.

ACIBADEM Healthcare Group was established in 1991 and has since grown to become Türkiye's leading private health services provider. With a network of 24 hospitals, 15 outpatient clinics, a thematic university and many other service companies across Türkiye, Bulgaria, Macedonia, Serbia and The Netherlands, ACIBADEM offers a comprehensive range of medical services, from primary care to specialized treatments and advanced surgical procedures.

Patient-Centric Care

At the heart of ACIBADEM's philosophy is a deep commitment to patient-centric care. Every aspect of our operations is designed to prioritize the well-being and satisfaction of our patients

and their families. From state-of-the-art medical facilities to compassionate and highly skilled healthcare professionals, ACIBADEM ensures that patients receive the highest quality of care at every step of their journey.

Innovative Technologies

ACIBADEM is at the forefront of medical innovation, continually investing in the latest technologies and medical advancements to enhance patient outcomes. From robotic surgery and advanced imaging techniques to personalized treatment plans using precision medicine, ACIBADEM harnesses the power of medical technology to deliver cutting-edge healthcare solutions.

International Reach

While rooted in Türkiye, ACIBADEM Healthcare Group has a global outlook and is committed to expanding its reach beyond national borders. With international patient services and collaborations with leading healthcare institutions worldwide, ACIBADEM welcomes patients from across the globe, offering them access to world-class healthcare services in Türkiye.

AT THE HEART OF ACIBADEM'S PHILOSOPHY IS A DEEP COMMITMENT TO PATIENTCENTRIC CARE. EVERY ASPECT OF OUR OPERATIONS IS DESIGNED TO PRIORITIZE THE WELL-BEING AND SATISFACTION OF OUR PATIENTS AND THEIR FAMILIES.

Future Directions

Looking ahead, ACIBADEM remains steadfast in its mission to redefine healthcare standards and set new benchmarks for excellence in patient care. With a focus on continuous innovation, collaboration, and a dedication to excellence, ACIBADEM is poised to shape the future of healthcare, both in Türkiye and beyond. As we continue to push the boundaries of medical science and redefine healthcare standards, ACIBADEM remains unwavering in its pursuit of excellence, ensuring that patients receive the highest quality of care, today and in the future.

A futuristic Command Center to manage the hospitals chain

As a globally renowned chain in the medical field and Türkiye’s leading Healthcare Group, ACIBADEM continues to grow rapidly. Following the inauguration of ACIBADEM Ataşehir Hospital, its 10th Hospital in Istanbul in September 2022, and the acquisition in 2023 of the largest private hospital and a medical center in Izmir, the third largest city in Türkiye, ACIBADEM network currently includes

24 hospitals and 15 medical centers across five countries, including Türkiye, Bulgaria, Macedonia, Serbia, and the Netherlands. Today ACIBADEM Healthcare Group is a global brand in medical tourism providing the highest quality of services using advanced technologies and expert teams meeting the international quality standards like Joint Commission International (JCI) and ISO 15189 Clinical Laboratory Accreditation Certificate. This is why every year many patients from different parts of the world travel to Türkiye, and they prefer ACIBADEM hospitals to receive treatment.

In ACIBADEM, we are working hard to continuously improve the patient experience. In order to enhance operational efficiency, improve patient outcomes, and elevate the quality of care, we set up a futuristic healthcare command center in the newest headquarters leveraging technology and real-time data analysis to make informed decisions and streamline hospital operations.

ACIBADEM IS AT THE FOREFRONT OF MEDICAL INNOVATION, CONTINUALLY INVESTING IN THE LATEST TECHNOLOGIES AND MEDICAL ADVANCEMENTS TO ENHANCE PATIENT OUTCOMES.

ACIBADEM UNIVERSITY

Leading the way in higher education & healthcare in Türkiye

ACIBADEM University, a prestigious institution at the forefront of higher education and healthcare research in Türkiye, continues to make significant strides in academic excellence, innovation, and community engagement.

Founded in 2007, ACIBADEM University has established itself as a pioneer in interdisciplinary education and advanced research, offering a wide range of undergraduate, graduate, and professional programs across various fields, including medicine, pharmacy, engineering, healthcare sciences, social sciences, management, and more. With a commitment to holistic learning and academic rigor, ACIBADEM University provides students with the knowledge, skills, and opportunities to excel in their chosen fields and make a positive impact on society. At the heart of ACIBADEM University's mission is its integration with the renowned ACIBADEM Healthcare Group, the leading healthcare services provider in Türkiye with a global reputation for excellence. This unique partnership enables students and faculty

members to collaborate closely with healthcare professionals, gain hands-on experience in state-of-the-art medical facilities, and contribute to groundbreaking research and innovation in healthcare delivery. ACIBADEM University is dedicated to fostering a culture of innovation and entrepreneurship, empowering students and researchers to explore new ideas, develop creative solutions to real-world challenges, and drive economic growth and social progress. Through its extensive network of industry partners, research centers, and innovation hubs, ACIBADEM University supports interdisciplinary collaboration and knowledge exchange, creating a dynamic ecosystem for innovation and discovery.

As a socially responsible institution, ACIBADEM University is actively engaged in community outreach and public service initiatives, working to address pressing societal issues and improve the well-being of individuals and communities across Türkiye and beyond. From healthcare outreach programs and educational initiatives to environmental sustainability projects and cultural exchange programs, ACIBADEM University is committed to making a meaningful difference in the lives of people and the world around us.

ACIBADEM UNIVERSITY'S CLINICAL AND ADVANCED SIMULATION EDUCATION (CASE) CENTER STANDS AS A PIONEERING INSTITUTION, RANKING AMONG THE TOP TWO CENTERS WORLDWIDE FOR ITS INNOVATIVE EDUCATIONAL MODEL

ACIBADEM University's CASE

ACIBADEM University's Clinical and Advanced Simulation Education (CASE) Center stands as a pioneering institution, ranking among the top two centers worldwide for its innovative educational model. This model integrates simulated patient experiences, electronic learning platforms, AI solutions, and state-of-the-art skill laboratories, distinguishing itself as a leader in medical education in Türkiye and the Region. Notably, it is the sole center in Türkiye to feature the Advanced Endoscopic/ Robotic Surgery Training Center, further enhancing its distinction within the field.

At CASE, undergraduate education programs are designed to equip students with essential clinical skills and management competencies. Post-graduation training programs offer advanced courses tailored to specific medical disciplines.

These courses aim not only to enhance technical proficiency but also to foster effective teamwork and communication skills among participants.

A hallmark of CASE's educational approach is its utilization of specialized software, which enables comprehensive tracking of training activities from electronic learning to postsimulation evaluation. This software facilitates personalized monitoring of each participant's progress, providing invaluable insights into performance metrics. With data collected

from 80 cameras, simulators, and medical devices within the center, trainers gain crucial information to optimize training effectiveness.

As ACIBADEM University continues to expand its academic offerings, research endeavors, and community impact, it remains steadfast in its commitment to excellence, innovation, and service, shaping the future of education and healthcare in Türkiye and beyond.

For more information about ACIBADEM University, please visit our website: www.acibadem.edu.tr/en

AT CASE, UNDERGRADUATE EDUCATION PROGRAMS ARE DESIGNED TO EQUIP STUDENTS WITH ESSENTIAL CLINICAL SKILLS AND MANAGEMENT COMPETENCIES

ACIBADEM LABMED... TÜRKIYE’S FIRST

ISO-15189 Accreditation Clinical Laboratory

Revolutionizing Healthcare Diagnostics

Established in 2002, ACIBADEM LABMED Clinical Laboratories offers comprehensive clinical laboratory services to ACIBADEM Healthcare Group as well as private and public institutions both in Türkiye and abroad.

ACIBADEM LABMED chain became very quickly a reference as a result of highly qualified and reliable laboratory services provided to numerous healthcare institutions globally.

ACIBADEM LABMED is Türkiye's leading chain of laboratories heralding a new era of advanced healthcare diagnostics in the region. With a commitment to advanced technology, unparalleled accuracy, and patient-centric

care, ACIBADEM LABMED aims to set the gold standard for laboratory services globally. Backed by the esteemed ACIBADEM Healthcare Group, ACIBADEM LABMED combines decades of medical expertise with state-of-the-art infrastructure to deliver a comprehensive range of diagnostic services. From routine blood tests to complex genetic analyses, the laboratory chain offers a diverse array of tests catering to the diverse needs of patients and healthcare providers alike.

"At ACIBADEM LABMED, we are driven by a passion for excellence and a dedication to improving healthcare outcomes for all." said

ACIBADEM LABMED IS TÜRKIYE'S LEADING CHAIN OF LABORATORIES HERALDING A NEW ERA OF ADVANCED HEALTHCARE DIAGNOSTICS IN THE REGION.

Professor Mustafa Serter, CEO of ACIBADEM LABMED. "Through our commitment to innovation, quality, and compassionate care, we aim to empower individuals and healthcare professionals with the insights they need to make informed decisions about their health."

What sets ACIBADEM LABMED apart is its unwavering focus on precision and reliability. Utilizing cutting-edge technology and adhering to stringent quality assurance protocols, the laboratory chain ensures the highest level of accuracy in every test result. Moreover, with a team of highly skilled medical professionals overseeing operations, patients can trust that they are in capable hands every step of the way.

In addition to its commitment to quality, ACIBADEM LABMED places a strong emphasis on accessibility and convenience. With a network of strategically located laboratories across Türkiye, including major cities and remote regions, the chain aims to make high-quality diagnostic services accessible to all segments of the population.

Furthermore, leveraging digital innovation, ACIBADEM LABMED offers convenient online appointment booking and result access, streamlining the entire diagnostic process for patients and healthcare providers.

As part of its mission to drive innovation in healthcare, ACIBADEM LABMED continuously invests in research and development to expand its test menu and introduce new diagnostic technologies. By staying at the forefront of

medical advancements, the laboratory chain remains poised to address emerging healthcare challenges and deliver cutting-edge solutions to its customers.

ACIBADEM LABMED invites patients, healthcare professionals, and stakeholders to experience the future of diagnostic excellence. With a relentless commitment to quality, innovation, and patient care, the laboratory chain is poised to transform the landscape of healthcare diagnostics in Türkiye and beyond.

For more information about ACIBADEM LABMED and its services, please visit our Website: www.acibademlabmed.com.tr

ACIBADEM LABMED INVITES PATIENTS, HEALTHCARE PROFESSIONALS, AND STAKEHOLDERS TO EXPERIENCE THE FUTURE OF DIAGNOSTIC EXCELLENCE

Innovative Healthcare Solutions Redefining the Industry

by ACIBADEM TECHNOLOGY

Established with a commitment to advancing healthcare through technology, ACIBADEM TECHNOLOGY has emerged as a trailblazer in the development and implementation of innovative healthcare solutions. Leveraging modern technologies, the company specializes in creating bespoke software, medical devices, and digital platforms that enhance patient care, optimize clinical workflows, and improve overall healthcare outcomes.

ACIBADEM TECHNOLOGY is a technological company that started to operate in 2015 with years of experience and expertise as a part of Acibadem Healthcare Group. ACIBADEM TECHNOLOGY offers its services, experiences and products to the market inside and outside of Türkiye. The major products provided by ACIBADEM TECHNOLOGY include:

• Cerebral Plus, Hospital Information System

• Astore, Medication and Medical Consumables Management System

• Lab Assistant, Laboratory Information System

• ACIBADEM Online, Patient Portal

ACIBADEM TECHNOLOGY also provides IT Project Management, Software and Infrastructure Consultancy and Establishing professional teams.

ACIBADEM Technology, as a service and product provider offers its services in 10 different cities in Türkiye and other countries with a total of 24 Hospitals, 15 Outpatient Clinics, affiliated companies and ACIBADEM University. In 2015, ACIBADEM TECHNOLOGY provided its services through Software and Infrastructure in ACIBADEM Healthcare Group, for:

• 3.500 doctors and 4.000 nurses,

• 2750 beds,

• 3.8 million outpatients,

• 300.000 inpatients, 120 operating

rooms and 100.000 surgeries,

• 7.8 million lab tests.

One of ACIBADEM Technology's flagship offerings is its groundbreaking healthcare command center, a centralized hub that harnesses advanced data analytics, real-time monitoring, and predictive analytics to optimize hospital operations and streamline patient care. This command center acts as a nerve center, enabling healthcare providers to make informed decisions, anticipate patient needs, and allocate resources efficiently.

Additionally, ACIBADEM TECHNOLOGY is recognized for its expertise in telemedicine solutions, remote patient monitoring systems, and digital health platforms. By bridging the gap between technology and healthcare delivery, the company empowers healthcare providers to deliver high-quality care to patients, regardless of geographical barriers. ACIBADEM TECHNOLOGY works to emerge as a premier technology firm, renowned for pioneering innovative solutions tailored for the global healthcare sector that transcend geographical boundaries. We are committed to providing innovative, customized solutions that align with

our customers' business requirements, while establishing robust systems and ensuring the delivery of high-quality services.

For more information visit our website: www.acibademtechnology.com

3.500 DOCTORS AND 4.000 NURSES.

ACIBADEM PROJECT MANAGEMENT... Leading the Way in Healthcare Infrastructure Development

20 Countries, 35 Cities, 2 Million sqm, 80 Projects

ACIBADEM PROJECT MANAGEMENT, a pioneering entity within the Turkish healthcare landscape, continues to set new standards in the realm of infrastructure development for healthcare facilities. With a steadfast commitment to excellence and innovation, ACIBADEM PROJECT MANAGEMENT has emerged as a key player in shaping the future of healthcare infrastructure both domestically and internationally.

About ACIBADEM PROJECT MANAGEMENT

ACIBADEM PROJECT MANAGEMENT aspiration is to be a global benchmark in healthcare investments, renowned for its distinctive expertise in design and execution, while simultaneously catering to the needs of both local and international healthcare sectors by delivering top-tier facilities of exceptional quality. ACIBADEM PROJECT MANAGEMENT stands at the forefront of healthcare infrastructure development, leveraging its expertise to deliver state-of-the-art facilities that meet the evolving needs of modern healthcare delivery. With a focus on efficiency, sustainability, and patient-centric design, ACIBADEM PROJECT MANAGEMENT has earned a reputation for excellence in the industry.

Key Highlights

ACIBADEM PROJECT MANAGEMENT offers a complete project management service including contract preparation, testing and commissioning management in pursuance of structure established in collaboration with the client. In cooperation with its professional team and local and global solution partners, APM inhibits an approach to predict and manage risks which may arise at all stages of the project process, including the investment decision making.

Innovative Solutions: ACIBADEM PROJECT MANAGEMENT employs innovative approaches and cutting-edge technologies to design and construct healthcare facilities that prioritize patient care, operational efficiency, and sustainability.

ACIBADEM PROJECT MANAGEMENT

OFFERS A COMPLETE PROJECT MANAGEMENT SERVICE INCLUDING CONTRACT PREPARATION, TESTING AND COMMISSIONING MANAGEMENT IN PURSUANCE OF STRUCTURE ESTABLISHED IN COLLABORATION WITH THE CLIENT.

National and International Reach: With projects spanning across Türkiye and beyond, ACIBADEM PROJECT MANAGEMENT has established itself as a trusted partner for healthcare infrastructure development on both a national and international scale.

Quality Assurance: Committed to upholding the highest standards of quality, ACIBADEM PROJECT MANAGEMENT ensures that all projects adhere to rigorous quality control measures and regulatory requirements, delivering facilities that meet and exceed industry benchmarks.

Customer-Centric Approach: At the heart of ACIBADEM PROJECT MANAGEMENT's philosophy is a dedication to customer satisfaction. By prioritizing client needs and preferences, the company collaborates closely with stakeholders to deliver tailor-made solutions that meet their unique requirements.

Some references

• 2018 Sharjah Private Hospital, UAE

• 2018 Abu Dhabi Transplantation Hospital, UAE

• 2017 Acıbadem International Medical center, THE NETHERLANDS

• 2017 UKC Banja Luka Hospital Modular Systems, BOSNIA

• 2016 Rostov-On-Don Hospital, RUSSIA

• 2015 Acıbadem Sistina Hospital, MACEDONIA

• 2013 Ayer Keroh Hospital, MALAYSIA

• 2012 Mosul Private Hospital, IRAQ

• 2012 Kirkuk General Hospital, IRAQ

• 2012 Bakü Hayat Clinic, AZERBAIJAN

• 2012 Basra El Zanaat Al Hayat Hospital, IRAQ

• 2011 Karbala maternity And Pediatric Hospital, IRAQ

• 2011 Libyan British Hospital, LIBYA

• 2010 Moscow Lapino Perinatal medical Center, RUSSIA

• 2008 Faruk Medical City Sulaimani, IRAQ

• All ACIBADEM Group’s facilities

As ACIBADEM PROJECT MANAGEMENT continues to lead the way in healthcare infrastructure development, the company

remains steadfast in its commitment to innovation, quality, and excellence. With a proven track record of success and a forwardthinking approach, ACIBADEM PROJECT MANAGEMENT is poised to shape the future of healthcare infrastructure, driving positive change and making a lasting impact on the global healthcare landscape.

For more information about ACIBADEM PROJECT MANAGEMENT and its services, please visit our Website: www.apy.com.tr

AT THE HEART OF ACIBADEM PROJECT MANAGEMENT'S PHILOSOPHY IS A DEDICATION TO CUSTOMER SATISFACTION.

ACIBADEM APLUS... Introduces Revolutionary Catering and Cleaning Solutions

To Elevate Healthcare Environments

Driven by a mission to provide exceptional support to healthcare providers, ACIBADEM APlus offers a comprehensive range of services encompassing facility management, catering, cleaning, and maintenance. By leveraging cutting-edge technology, best practices, and a team of highly skilled professionals, the company ensures that healthcare facilities maintain the highest standards of cleanliness, safety, and efficiency.

ACIBADEM APlus, a leading Turkish company specializing in providing cleaning and catering services for healthcare facilities, continues to redefine standards in the industry with its innovative solutions and unwavering commitment to excellence. With a focus on delivering top-notch services tailored to meet

the unique needs of healthcare institutions, ACIBADEM APlus is revolutionizing the way healthcare facilities are managed and operated.

APLUS WHAT WE OFFER

One of the key differentiators of Acıbadem APlus is its ability to tailor its services to meet the specific requirements of each healthcare institution. Whether it's managing a hospital, clinic, laboratory or medical center, the company provides customized solutions that enhance operational efficiency, optimize resource utilization, and improve overall patient experience.

Cleaning Services

• General janitorial services including cleaning of floors, walls, and surfaces in

WITH A FOCUS ON DELIVERING TOPNOTCH SERVICES

TAILORED TO MEET THE UNIQUE NEEDS OF HEALTHCARE INSTITUTIONS, ACIBADEM APLUS IS REVOLUTIONIZING THE WAY HEALTHCARE FACILITIES ARE MANAGED AND OPERATED.

patient rooms, corridors, waiting areas, and administrative offices.

• Disinfection and sanitization of hightouch surfaces to maintain infection control standards.

• Sterilization of medical equipment and instruments.

• Biohazard cleanup and disposal services in compliance with safety regulations.

• Specialized cleaning for operating rooms, intensive care units, and other sensitive areas.

Catering Services

• Meal preparation and delivery for patients according to dietary restrictions and nutritional guidelines.

• Catering for hospital cafeterias or dining areas, providing a variety of healthy and nutritious options.

• Specialized menus for patients with specific medical conditions or dietary needs.

• Compliance with food safety standards and regulations to prevent foodborne illnesses.

Additional Services

• Laundry and linen services to ensure clean and hygienic bedding, towels, and other linens.

• Waste management and recycling services to dispose of medical and nonmedical waste responsibly.

• Staff training on infection control protocols, food safety practices, and other relevant topics.

• Emergency response services for unexpected incidents such as spills or outbreaks.

Quality Assurance

• Regular inspections and quality checks to ensure that cleaning and catering services meet the highest standards.

• Feedback mechanisms to gather input from hospital staff and patients for continuous improvement.

• Adherence to industry best practices and compliance with regulatory requirements in healthcare settings.

Overall, ACIBADEM APlus plays a crucial role in maintaining a safe, hygienic, and comfortable environment for patients, staff, and visitors. The company contributes to the overall well-being and efficiency of healthcare facilities by supporting infection control efforts and providing nutritious meals that aid in the recovery process.

For more information about ACIBADEM APlus services, please visit our Website: www.aplus.web.tr

ONE OF THE KEY DIFFERENTIATORS OF ACIBADEM APLUS IS ITS ABILITY TO TAILOR ITS SERVICES TO MEET THE SPECIFIC REQUIREMENTS OF EACH HEALTHCARE INSTITUTION.

ACIBADEM MOBIL... Revolutionizes Home care with Innovative Services

ACIBADEM MOBIL's meticulously crafted healthcare services are making quality care closer to everyone. Whether in the comfort of your home or amidst the busyness of your workplace, ACIBADEM MOBIL staff is just a click away for your healthcare needs. With our high standards and personalized approach, we offer the easiest way to lead a healthy life in Istanbul Türkiye.

ACIBADEM MOBIL is a pioneering healthcare company based in Türkiye, having as mission to improve access to healthcare services. ACIBADEM MOBIL was founded in July 2008 as an integral part of the comprehensive ecosystem of ACIBADEM Healthcare Group. Catering to both individuals and institutions,

ACIBADEM MOBIL develops targeted solutions to meet diverse healthcare needs. Our Medical Call Center, operational round the clock, 7 days a week, stands ready to provide prompt and reliable health-related assistance to all those seeking our services.

MOBIL’s primary business lines are Ambulance and Home Care Services, HSE, and Digital Health with a focus on innovation and excellence, including telemedicine consultations, mobile health applications, home healthcare services, health monitoring devices, checkup services and healthcare education programs.

1. Telemedicine Consultations: Through state-of-the-art telecommunication

ACIBADEM MOBIL IS A PIONEERING HEALTHCARE COMPANY BASED IN TÜRKIYE, HAVING AS MISSION TO IMPROVE ACCESS TO HEALTHCARE SERVICES.

technologies, patients can access healthcare professionals remotely, receiving timely medical advice and consultations from the comfort of their homes.

2. Mobile Health Applications: ACIBADEM MOBIL offers intuitive mobile applications equipped with features such as symptom checkers, medication reminders, and health trackers, empowering users to take control of their health and well-being.

3. Home Healthcare Services: Recognizing the importance of continuity of care, ACIBADEM MOBIL brings healthcare services directly to patients' homes, including home nursing, physiotherapy, and medical equipment rental, ensuring optimal recovery and comfort.

4. Health Monitoring Devices: Leveraging the latest advancements in wearable technology, Acıbadem Mobil provides devices for continuous health monitoring, enabling individuals to track vital signs and receive alerts for any deviations from normal parameters.

5. Healthcare Education and Awareness Programs: Acıbadem Mobil is committed to promoting health literacy and awareness among

the community. Through educational programs, workshops, and seminars, the company strives to empower individuals to make informed decisions about their health.

Dr. Behiç Berk KUĞU, M.D, CEO of ACIBADEM MOBIL, stated: "At ACIBADEM MOBIL, we believe that everyone deserves access to quality healthcare, regardless of their location or circumstances. Our comprehensive range of services is designed to meet the diverse needs of our patients and empower them to lead healthier lives. We are excited to embark on this journey of transformation and look forward to making a meaningful impact on the healthcare landscape in our country, and in a near future, abroad."

For more information visit our website: www.acibademmobil.com.tr

OUR MEDICAL CALL CENTER, OPERATIONAL ROUND THE CLOCK, 7 DAYS A WEEK, STANDS READY TO PROVIDE PROMPT AND RELIABLE HEALTH-RELATED ASSISTANCE TO ALL THOSE SEEKING OUR SERVICES.

Revolutionizing Healthcare ...The Impact of AI on Medical Imaging and Patient Care

Artificial Intelligence (AI) is initiating a transformative era in the field of medical imaging, promising to redefine the parameters of diagnostic accuracy, patient care, and the overall efficiency of healthcare delivery. As these technologies continue to evolve and mature, their integration into medical practices is becoming increasingly indispensable, a trend underscored by recent studies in this domain. This article delves into the multifaceted role of AI in medical imaging, highlighting its potential to augment diagnostic precision, enhance image quality, and facilitate early disease detection, all while supporting healthcare professionals in making more informed decisions.

The Role of AI in Medical Imaging

AI has established itself as a cornerstone of modern medical imaging technologies. Through advanced algorithms capable of detecting and segmenting anatomical landmarks, AI assists in the identification of organs, tumors, lesions, and other abnormalities within medical images. This capability not only streamlines the diagnostic process but also enhances the accuracy of interpretations made by radiologists and physicians.

Despite its promising applications, it is essential to acknowledge that AI does not aim to replace the nuanced judgment and expertise of human professionals. Instead, it serves as a powerful adjunct tool that supplements the decision-making process, aiding in the refinement of patient care strategies. It's a symbiotic relationship where AI-driven insights complement the clinical acumen of medical practitioners.

AI in Disease Diagnosis and Treatment Planning

In the realm of disease diagnosis, AI's value is particularly pronounced. Leveraging vast datasets of classified medical images, AI algorithms, especially those based on deep learning, can be trained to differentiate between benign and malignant tumors, identify specific disease types such as pneumonia or Alzheimer's, and offer predictive insights that could guide treatment options. This capability not only augments the diagnostic accuracy but also enriches the therapeutic planning process, enabling a more tailored approach to patient management.

Enhancing the Quality of Medical Images

One of the standout contributions of AI in medical imaging is its ability to significantly improve image quality. By reducing noise and enhancing the clarity and precision of images, AI algorithms make it easier for healthcare professionals to analyze and interpret medical data. This advancement is crucial in conditions where the distinction between healthy and pathological tissues is subtle yet significant for

diagnosis and treatment planning. Moreover, AI's capability to reconstruct high-quality images from incomplete or low-quality data presents a groundbreaking solution to common challenges in medical imaging, ensuring that even under less-than-ideal conditions, the diagnostic value of medical images is not compromised.

Predictive Models and Early Detection

AI's predictive modeling capabilities herald a new frontier in medical imaging, enabling the early detection of diseases and the identification of optimal treatment pathways. These models can analyze patterns within medical images that may indicate the early stages of a disease, even before clinical symptoms manifest. Such early intervention potential is transformative, offering a pathway to significantly improve patient outcomes through timely treatment.

Quantitative Analysis and Treatment Monitoring

Beyond diagnosis, AI algorithms play a critical role in the quantitative analysis of medical images. This includes measuring tumor sizes, tracking disease progression, and evaluating treatment responses. This quantitative information is invaluable for clinicians in planning and monitoring treatment, offering a more objective and data-driven approach to patient care.

The integration of AI into medical imaging is a testament to the relentless pursuit of excellence in healthcare. By enhancing diagnostic accuracy, streamlining the analysis process, and facilitating early disease detection, AI technologies are setting new standards in medical practice. However, it's imperative to approach these advancements with a balanced perspective, recognizing that AI serves to augment, not replace, the critical role of healthcare professionals. As AI technologies continue to evolve, their adoption must be guided by careful consideration, ethical practices, and a commitment to improving patient outcomes.

ONE OF THE STANDOUT CONTRIBUTIONS OF AI IN MEDICAL IMAGING IS ITS ABILITY TO SIGNIFICANTLY IMPROVE IMAGE QUALITY. BY REDUCING NOISE AND ENHANCING THE CLARITY AND PRECISION OF IMAGES, AI ALGORITHMS MAKE IT EASIER FOR HEALTHCARE PROFESSIONALS TO ANALYZE AND INTERPRET MEDICAL DATA. THIS ADVANCEMENT IS CRUCIAL IN CONDITIONS WHERE THE DISTINCTION BETWEEN HEALTHY AND PATHOLOGICAL TISSUES IS SUBTLE YET SIGNIFICANT FOR DIAGNOSIS AND TREATMENT PLANNING.

"The Blockchain Health Revolution: Transforming Healthcare One Block at a Time"

Dr. Samer Ellahham, MD, Cleveland Clinic Abu Dhabi

In recent years, blockchain technology has emerged as a game-changer in various industries, including finance, supply chain management, and even voting systems. However, its potential in healthcare is often overlooked. In this article, we will provide a simplified explanation of blockchain and explore its applications and limitations in the healthcare sector.

What is Blockchain?

At its core, blockchain is a decentralized and immutable digital ledger. It is a chain of blocks, where each block contains a list of transactions. These transactions are recorded in a transparent and secure manner, eliminating the need for intermediaries such as banks or brokers.

The real magic of blockchain lies in its decentralized nature. Instead of relying on a central authority, like a bank, to validate and

authorize transactions, blockchain utilizes a network of computers, known as nodes, spread across the globe. These nodes work together to verify and validate transactions, ensuring the integrity and security of the data.

Blockchain Applications in Healthcare:

1. Secure and Transparent Medical Records:

One of the most significant applications of blockchain in healthcare is the management of medical records. Currently, patient records are scattered across various healthcare providers and are often prone to errors, miscommunication, and security breaches. By utilizing blockchain, medical records can be securely stored and accessed by authorized parties. Patients can have full control over their data, granting access to healthcare providers as needed, while ensuring the privacy and integrity of their information.

THE REAL MAGIC OF BLOCKCHAIN LIES IN ITS DECENTRALIZED NATURE. INSTEAD OF RELYING ON A CENTRAL AUTHORITY, LIKE A BANK, TO VALIDATE AND AUTHORIZE TRANSACTIONS, BLOCKCHAIN UTILIZES A NETWORK OF COMPUTERS, KNOWN AS NODES, SPREAD ACROSS THE GLOBE.

2. Drug Traceability and Supply Chain Management: The pharmaceutical industry faces challenges in tracking the authenticity and provenance of drugs. Counterfeit medicines can infiltrate the supply chain, putting patients' health at risk. By implementing blockchain, the entire drug supply chain can be recorded and tracked, ensuring the authenticity and quality of medications. This transparency can also help prevent drug shortages, as the movement of drugs from manufacturers to patients can be efficiently monitored.

3. Clinical Trials and Research: Blockchain technology can revolutionize the way clinical trials are conducted. Currently, the process is often slow, expensive, and prone to manipulation. By utilizing blockchain, the entire clinical trial process can be recorded and audited, ensuring the transparency and integrity of the data. This can lead to faster and more reliable research outcomes, benefiting both patients and healthcare providers.

Limitations of Blockchain in Healthcare:

While blockchain holds immense potential, it is important to acknowledge its limitations in the healthcare sector:

1. Scalability: Blockchain technology, particularly in its current form, faces challenges in scaling to handle the vast amount of data generated in the healthcare sector. As healthcare generates massive amounts of data, from electronic health records to medical imaging, blockchain may struggle to handle the volume and speed required for real-time applications.

2. Regulatory and Legal Challenges: The implementation of blockchain in healthcare must navigate complex regulatory and legal frameworks. Compliance with privacy laws, such as the General Data Protection Regulation (GDPR), is crucial. Additionally, defining data ownership and consent management on the blockchain can be a complex task, requiring collaboration between stakeholders and regulatory bodies.

3. Integration with Existing Systems: Integrating blockchain technology with existing healthcare systems poses a significant challenge. Many healthcare organizations have invested heavily in their current infrastructure, making a complete overhaul for blockchain integration impractical and costly. Seamless integration and interoperability with legacy systems must be carefully planned and executed.

4. Data Privacy and Security Concerns: While blockchain is known for its security, it is not completely immune to vulnerabilities. While the data stored on the blockchain is encrypted and tamper-proof, there are potential risks associated with the exposure of patient identities and medical information. Additional layers of security protocols and encryption methods must be implemented to ensure the privacy and security of sensitive healthcare data.

5. Human Error and Trust Issues: Despite the technological advancements offered by blockchain, human error can still occur. Data entry mistakes, incorrect coding, and other human factors can compromise the accuracy and reliability of the data stored on the blockchain. Additionally, trust in the technology and its widespread adoption among healthcare providers, patients, and regulatory bodies is essential for its success.

Despite these limitations, blockchain technology holds immense promise for transforming the healthcare industry. Its potential to securely store and share medical records, track drug supply chains, and improve clinical research is undeniable. However, careful consideration must be given to scalability, regulatory compliance, integration challenges, data privacy, and trust for successful implementation.

In conclusion, blockchain technology has the potential to revolutionize healthcare by ensuring secure and transparent medical records, enhancing drug traceability, and improving clinical trials and research. While there are limitations to overcome, with proper planning, collaboration, and technological advancements, blockchain can pave the way for a more efficient, secure, and patient-centric healthcare system.

BLOCKCHAIN TECHNOLOGY HAS THE POTENTIAL TO REVOLUTIONIZE HEALTHCARE BY ENSURING SECURE AND TRANSPARENT MEDICAL RECORDS, ENHANCING DRUG TRACEABILITY, AND IMPROVING CLINICAL TRIALS AND RESEARCH. WHILE THERE ARE LIMITATIONS TO OVERCOME, WITH PROPER PLANNING, COLLABORATION, AND TECHNOLOGICAL ADVANCEMENTS, BLOCKCHAIN CAN PAVE THE WAY FOR A MORE EFFICIENT, SECURE, AND PATIENT-CENTRIC HEALTHCARE SYSTEM.

Exploring the Frontiers of Cardiac Care: Advanced Diagnostic and Treatment Strategies for Congenital Heart Defects

Congenital heart defects, recognized as one of the most common types of birth anomalies, stem from irregular heart development during the first eight weeks of gestation. These defects encompass a wide array of malformations affecting the structure of the heart's walls, valves, blood vessels, and chambers. These anomalies can significantly impede the heart's functionality, leading to serious blood flow disorders.

The spectrum of congenital heart defects varies greatly, ranging from mild conditions that might not demand immediate medical attention to severe cases requiring urgent surgical intervention shortly after birth.

For those diagnosed, a lifelong journey of specialized care and regular medical oversight is often necessary. The paramount importance of early detection and adept management of these defects cannot be overstated, as they are crucial in securing the best possible outcomes for the affected children.

Bridging Gaps with Medical Innovations: Prenatal Diagnosis

Recent advancements in medical science have opened up new prospects for the prenatal diagnosis of congenital heart defects. Today, a plethora of advanced imaging techniques are at the disposal of medical professionals, allowing for an in-depth examination of the fetal heart before birth.

The choice of diagnostic method is meticulously tailored, taking into consideration the specifics of the pregnancy and adhering to the advice of a specialized medical team. This team, expert in pediatric heart diseases and congenital defects, plays a pivotal role in assessing the diagnostic outcomes and

formulating a comprehensive care and treatment plan for the fetus.

Advanced Diagnostic Modalities:

Ultrasound Examination

(Echocardiography): Standing at the forefront of prenatal diagnostics, echocardiography is a cornerstone in identifying fetal heart defects. This non-invasive technique produces detailed imagery of the heart's anatomy, enabling the detection of structural anomalies, valve disorders, and other crucial indicators of congenital heart defects.

3D/4D Ultrasound Imaging: The advent of 3D/4D ultrasound imaging has significantly enhanced the accuracy of congenital heart defect diagnoses. By offering a multidimensional view of the heart's structure, this technology aids in a more comprehensive evaluation of cardiac function, both before and after birth. The implementation of this sophisticated technique necessitates the expertise of specialists trained in advanced cardiac imaging, ensuring the delivery of precise assessments and the formulation of optimal treatment strategies.

Indirect Fetal Testing: A suite of maternal blood tests, including the double serum test and the integrated pregnancy test, can now hint at potential congenital heart defects. Abnormal findings from these tests could warrant further detailed examinations to ascertain the existence of heart anomalies.

Genetic Analysis and Molecular Testing:

Exploring the genetic underpinnings of congenital heart defects, modern medicine employs genetic and molecular testing to

THE SPECTRUM OF CONGENITAL HEART DEFECTS

VARIES GREATLY, RANGING FROM MILD CONDITIONS THAT MIGHT NOT DEMAND IMMEDIATE MEDICAL ATTENTION TO SEVERE CASES REQUIRING URGENT SURGICAL INTERVENTION SHORTLY AFTER BIRTH. FOR THOSE DIAGNOSED, A LIFELONG JOURNEY OF SPECIALIZED CARE AND REGULAR MEDICAL OVERSIGHT IS OFTEN NECESSARY.

identify specific mutations. This approach involves analyzing samples of blood or tissue to uncover genetic anomalies that may be linked to heart defects.

Interventional Innovations:

Fetal Cardiac Catheterization: A groundbreaking minimally invasive procedure, fetal cardiac catheterization, introduces the possibility of correcting certain heart defects within the womb. Guided by state-of-the-art imaging techniques, this method involves the precise insertion of a catheter to address and rectify anomalies, highlighting the strides made towards in utero treatment.

Surgical Milestones: Open Heart Surgery During Pregnancy

The feasibility of conducting open heart surgery during pregnancy marks a monumental leap in congenital heart defect treatment. This highly sensitive decision requires a comprehensive evaluation process, factoring in the specifics of the congenital defect, the overall health of the mother, and the anticipated impact on the fetus. The deliberation over this option underscores the intricate balance between advancing medical capabilities and the ethical considerations inherent in such pioneering interventions.

Conclusion

The landscape of cardiac care, particularly for congenital heart defects, is continually evolving, driven by remarkable strides in diagnostic and therapeutic methodologies.

The integration of advanced imaging techniques, alongside innovative surgical and interventional strategies, has vastly improved the prognosis for affected individuals, offering them a beacon of hope. As the medical community ventures further into the realms of prenatal diagnosis and treatment, the prospects for early intervention and improved outcomes for children with congenital heart defects continue to brighten, emblematic of the ongoing revolution in cardiac care.

'OR of the future' houses new tech to view the brain like never before

Peter Warnke, MD, and a colleague performs a delicate neurosurgery in the high-tech OR. Relevant images of the patient's brain are displayed on the screens to guide the procedure.

You may have heard stories of patients remaining awake and being asked to converse or even sing while receiving brain surgery. Although it may seem strange, this practice has long served as an effective way for brain surgeons to assess brain function mid-surgery to help ensure they don’t damage important tissue or neurons.

But leading neurosurgeons now have tools that far eclipse the precision of those “awake” brain surgeries.

At the University of Chicago Medicine, architects, builders, technicians and neurosurgery experts have collaborated to create a new kind of operating room designed to give physicians more information than ever to guide neurosurgical procedures.

"Our vibrant neurosurgery research program demanded real-time technology integration as the next logical step," said Peter Warnke, MD, Director of Stereotactic and Functional Neurosurgery at UChicago Medicine.

This “OR of the future,” as Warnke called it, opened in January 2023, and it features cutting-edge instruments and high-definition screens that allow brain surgeons to scan and view key areas of the brain throughout an operation. Since then, UChicago Medicine neurosurgeons have used the technology for procedures as intricate and precise as electrode implantation and laser surgery that restored a patient’s senses and left them seizure-free.

Functional imaging mid-surgery

Warnke says the highlight of the technology integration is a new intraoperative MRI recently installed in the OR at UChicago Medical Center in Hyde Park.

Now, doctors can run functional MRI (fMRI) scans mid-surgery to see not only how the brain is arranged but also how it’s working in real time. This can include looking at the brain’s response to surgical interventions like electrical stimulation, performing metabolic imaging to see how different brain cells produce and use energy, and tracking physiological responses.

The installation required significant planning: MRI technology requires copper shielding

to be built into the room’s walls to prevent outside radio frequencies from distorting the imaging and to shield the outside world against the powerful magnetic field generated by the magnet.

In addition to the intraoperative MRI technology, UChicago Medicine has also added two complementary mobile CT scanners, including an ultrafast, 64-slice helical scanner that can be wheeled around for use in multiple ORs.

As part of this 3D imaging setup, the Department of Neurosurgery also recently acquired new neurosurgical robots — the Autoguide and ROSA systems — to make all surgeries as precise and safe as possible.

“We can combine intraoperative MRI scans and functional imaging with intraoperative CT scans and robotics during surgery, allowing true hybrid surgeries that give us the best advantages of all these technologies,” Warnke said.

'A major paradigm shift'

UChicago Medicine staff can use the OR’s high-definition wall screens to view output from the MRI, CT scans and all surgical plans, including robotic trajectories and relevant images from a patient’s medical record. The ability to refer to these images throughout surgery can help surgeons individualize their surgical approach down to the millimeter.

“In each patient, we’re able to evaluate the brain circuitry and target those circuits precisely and individually,” Warnke said.

They can also look at the connections between different areas of the brain, which is essential for complex procedures like pediatric epilepsy surgery and treating deep-seated tumors.

“We have moved from simplified removal of brain tissue to sophisticated disconnections and modulation of seizure onset zones,” Warnke said. “With precise imaging, we can use minimally invasive tools like interstitial lasers and responsive closed-loop stimulation systems to reduce morbidity significantly. It’s a major paradigm shift in neurology.”

Each surgical step can include a new scan that allows experts to update the surgical plan and confirm accuracy. And when surgeons

NOW, DOCTORS CAN RUN FUNCTIONAL MRI (FMRI) SCANS

MID-SURGERY TO SEE NOT ONLY HOW THE BRAIN IS ARRANGED BUT ALSO HOW IT’S WORKING IN REAL TIME. THIS CAN INCLUDE LOOKING AT THE BRAIN’S RESPONSE TO SURGICAL INTERVENTIONS

LIKE ELECTRICAL STIMULATION, PERFORMING METABOLIC IMAGING TO SEE HOW DIFFERENT BRAIN CELLS PRODUCE AND USE ENERGY, AND TRACKING PHYSIOLOGICAL RESPONSES.

are removing or destroying a tumor, they can perform a scan to ensure the treatment is as complete as possible before closing incisions.

Warnke said the new OR setup also will enhance the education of trainees at the academic medical center.

“It’s invaluable for trainees to see the effect of a surgery visually while it is being performed,” he said.

Enabling tomorrow’s neuroscience

For years, UChicago Medicine has been a leader in brain-computer interface research related to motor control and sensation. Warnke has performed surgeries that re-created a sense of touch and motor control via prosthetic hands for paralyzed patients, most recently in one of the new ORs.

“The impact of intraoperative imaging on our brain-machine program in particular is huge,” Warnke said. “We can now look at brain function as we are placing an electrode or laser fiber, thus guiding it more precisely than ever before.”

Immediately after an implant is placed, neuroscientists can use the various imaging technologies to test the implant’s function before concluding the surgery. This allows them to collect important data for research analysis and also make sure the implant is working properly, minimizing the need for follow-up surgeries to tweak its placement.

In October 2023, the UChicago research group received a $3.4 million R01 grant from the National Institutes of Health to further propel their research into developing more sophisticated brain-computer interfaces. Specifically, the researchers aim to develop brain-computer decoders that emulate the seamless coordination of arm and hand movements — and to test these advanced decoders within a virtual reality environment that simulates daily activities.

Warnke emphasizes that he is just one member of the university’s “vibrant neurosurgery research program.”

For example, colleagues at the Grossman Center for Quantitative Biology and Human Behavior are bringing unparalleled computational techniques to vast neuroscience datasets,

while others are investigating ways to improve treatments for epilepsy, vascular malformations and brain tumors with less invasive diagnostic techniques and more effective surgeries —efforts that will receive a boost from the new OR’s capabilities.

“It’s all part of a wider realm of innovative neuroscience that is bringing new technology and exciting research with immediate benefit for the patient to the OR,” Warnke said.

Peter Warnke, MD Professor of Neurology and Neurological Surgery/ Director, Stereotactic and Functional Neurosurgery

Internationally renowned neurosurgeon Peter Warnke, MD, has performed more than 5,000 stereotactic surgeries and more than 2,000 brain tumor surgeries. Dr. Warnke provides neurosurgical care for the treatment of adults and children with movement disorders, epilepsy and brain tumors.

FOR MORE INFORMATION, VISIT

WWW.UCHICAGOMEDICINE.ORG/GLOBAL

IN OCTOBER 2023, THE UCHICAGO RESEARCH GROUP RECEIVED A $3.4 MILLION R01 GRANT FROM THE NATIONAL INSTITUTES OF HEALTH TO FURTHER PROPEL THEIR RESEARCH INTO DEVELOPING MORE SOPHISTICATED BRAIN-COMPUTER INTERFACES.

SPECIFICALLY, THE RESEARCHERS AIM TO DEVELOP BRAIN-COMPUTER DECODERS THAT EMULATE THE SEAMLESS COORDINATION OF ARM AND HAND MOVEMENTS — AND TO TEST THESE ADVANCED DECODERS WITHIN A VIRTUAL REALITY ENVIRONMENT THAT SIMULATES DAILY ACTIVITIES.

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International Sales Director of Lépine Arnaud Teulet

Advancing Orthopedic Solutions

In the realm of orthopedic innovation, Lépine, a leading French manufacturer, stands at the forefront with its commitment to excellence and patient-centric solutions. Arnaud Teulet, the International Sales Director of Lépine, shares his insights into the company's approach to innovation, global expansion, and the future of orthopedic care.

Can you tell us about yourself and your background in the medical device industry?

Certainly. I'm Arnaud Teulet, and I've dedicated the past two decades of my career to the medical device industry. With six years specifically at Lépine, I've focused on advancing orthopedic solutions and ensuring quality care for patients worldwide.

What are the key orthopedic products offered by Lépine?

Lépine specializes in joint reconstruction devices, particularly for hip, knee, shoulder, and hand surgeries. Our products are designed to meet the evolving needs of surgeons and patients, incorporating cutting-edge technologies developed by French surgeons.

What sets Lépine's orthopedic products apart from other companies?

What truly distinguishes Lépine is our close collaboration with customers and our unwavering commitment to innovation. We

prioritize exceeding industry standards and regulations globally, ensuring that our products offer tangible benefits in terms of both shape and functionality.

How does Lépine ensure that its orthopedic products meet industry standards and regulations globally?

At Lépine, we take a proactive approach to regulatory compliance. We independently register our products in each country, ensuring thorough oversight of their distribution and implementation. Additionally, we partner with distributors who share our commitment to product training and patient care.

Can you tell us about the research and development process behind Lépine's latest innovations?

Our research and development efforts are driven by collaboration with a network of surgeons. By addressing real-world challenges faced by patients, we ensure that our implants allow patients a rapid return to normal life.

BY ADDRESSING REAL-WORLD CHALLENGES FACED BY PATIENTS, WE ENSURE THAT OUR IMPLANTS OFFER TANGIBLE BENEFITS IN TERMS OF SHAPE AND FUNCTIONALITY. THIS APPROACH ALLOWS US TO STAY AT THE FOREFRONT OF ORTHOPEDIC INNOVATION

Does Lépine offer customized orthopedic solutions for each patient?

While some companies offer customized solutions, Lépine takes a different approach. We offer a range of orthopedic solutions within each product line, allowing for greater flexibility while ensuring optimal fit and performance for patients.

How does Lépine collaborate with international partners to enhance its products?

Lépine primarily collaborates within its group but also partners with distributors in specific regions to expand our reach. We see promising opportunities for growth in regions like the GCC countries, where there is a growing demand for orthopedic solutions.

Can you share a success story about a particularly impactful orthopedic solution provided by Lépine?

Certainly. One notable success story is our hand prosthesis, MaÏa, which has revolutionized the treatment of hand arthrosis. MaÏa offers an alternative to bone removal and has become the standard

worldwide, showcasing the impact of Lépine's innovations on patient care.

What are your thoughts on the role of Artificial Intelligence in the future of orthopedic care?

Lépine recognizes the potential of Artificial Intelligence in enhancing orthopedic care. We are exploring its integration in marketing, data collection, and engineering processes to improve patient outcomes through personalized treatment planning. AI will undoubtedly play a significant role in the future of orthopedic care, enhancing efficiency and precision.

Any final thoughts or messages about Lépine and its commitment to orthopedic excellence?

Absolutely. At Lépine, our commitment to innovation and quality is unwavering. While price considerations are important, they should never compromise the value of advancements in orthopedic care. We remain dedicated to upholding our legacy of excellence and innovation, ensuring the highest standards of care for patients worldwide.

LÉPINE RECOGNIZES

THE POTENTIAL OF ARTIFICIAL INTELLIGENCE IN ENHANCING ORTHOPEDIC CARE. WE ARE EXPLORING ITS INTEGRATION IN MARKETING, DATA COLLECTION, AND ENGINEERING PROCESSES TO IMPROVE PATIENT OUTCOMES THROUGH PERSONALIZED TREATMENT PLANNING.

Ensuring a safe stock of blood is a major healthcare challenge, due to insufficient blood donations

As per the World Health Organization (WHO), a safe stock of blood should equate to 1% of a country’s population; a target that several countries around the world are lagging behind. Challenges are many and vary between lack of awareness, taboos, stigmas, or simply scare of the needle.

To help remedy this global issue, Abbott has developed a new technology called the mixed reality experience to help attract a larger number of people to donate blood. "Hospitals" magazine had the opportunity to meet the team at Abbott behind this innovation and witness this experience closely. To learn more about the mixed reality experience, we hosted

Omar Riyal, Divisional Vice President at Abbott’s transfusion medicine business.

What is the mixed reality experience?

It’s a first-of-its-kind consumer-focused innovation developed by Abbott to address the global challenge of sustaining a reliable blood supply. The experience which is designed to attract the young generation of blood donors, was developed based on research that natural settings are the most preferred environment for blood donors.

How does it really work?

Participants wear a mixed reality headset to embark on a digital world, represented by a

WE GARNERED VERY POSITIVE FEEDBACK FROM VARIOUS STAKEHOLDERS DURING MEDLAB, WHERE THE HEADSET WAS SHOWCASED.

whimsical garden, while listening to soothing music. The process is completely controlled through eye tracking. This immersive digital experience makes the blood donating process easier and more comfortable, as it distracts donors by adding an element of immersive high-tech mixed reality.

How safe is the experience?

It is a very safe experience: donors' eyes are always visible during donation to ensure constant monitoring, evaluation and interaction by the blood donation professional. Participants wear lightweight mixed reality headsets to enter the digital world, but remain fully aware of their surroundings, which ensures a convenient and safe experience.

How different is mixed reality from virtual reality?

Mixed reality is similar to virtual reality but allows participants to still see the real world around them, as they embark on the digital world. Donors are offered a quick tutorial on the headsets and the overall experience prior to use.

Where has the technology been launched so far?

We were thrilled to partner with Blood Centers of America, the largest blood supplier network in the U.S., to launch the experience in the US last year. We have more than 10 blood banks already using it in the US and seeing encouraging results. We are seeing that mixed reality helps with the return rate of donors compared with those who did not try the experience. We are currently looking to roll it out around the world, including the Middle East. In fact, we garnered very positive feedback from various stakeholders during MEDLAB, where the headset was showcased.

In your opinion, what would be a maindriver for the adoption of the new technology?

Data and research remain an irrefutable driver. As a matter of fact, a recent pilot study conducted by Abbott and Blood Centers of America showed that the mixed reality experience helps ease stress and encourages people

to donate again. 68.4% of participants who reported pre-donation anxiety said the mixed reality experience helped ease their feelings of anxiety, while 89.2% of donors who tried mixed reality said they were likely to donate blood again. I believe these insights are very encouraging and testify for the positive impact of the new technology.

How do you make your technologies and products more sustainable and what are your key priorities for the region?

We are in the business of health, the precursor of a sustainable future. To us, sustainability means putting people at the center of everything we do; that’s our pledge. Today more than 2 billion people are positively impacted by our innovative products, and we aim to reach 3 billion people by 2030. Therefore, whenever we develop a life-changing technology or innovate a new product or solution, we strive to make them more accessible and affordable. Our aim is to make a long-term impact on those we are here to serve.

IT IS A VERY SAFE EXPERIENCE: DONORS' EYES ARE ALWAYS VISIBLE DURING DONATION TO ENSURE CONSTANT MONITORING, EVALUATION AND INTERACTION BY THE BLOOD DONATION PROFESSIONAL.

PARTICIPANTS WEAR LIGHTWEIGHT MIXED REALITY HEADSETS TO ENTER THE DIGITAL WORLD, BUT REMAIN FULLY AWARE OF THEIR SURROUNDINGS, WHICH ENSURES A CONVENIENT AND SAFE EXPERIENCE.

On the sidelines of its participation in the Arab Health Exhibition and Conference 2024

"Mazaya" Medical Company continues its journey of excellence and enhances its presence with agreements and awards

Mazaya Medical Trading Company continues to support the healthcare sector in Qatar by providing the latest medical supplies. It is a leading company in the field of supplying advanced medical equipment, hospital furniture, and the latest global surgical solutions. The Arab Health Exhibition and Conference 2024 marked a significant shift towards enhancing the company's status through the signing of agreements and contracts for strategic partnerships. These agreements open wide horizons for introducing more advancements in the healthcare sector in Qatar, and they contribute effectively to enhancing its services and raising its standard to become one of the most important healthcare service providers in the world.

"Mazaya": A collaboration that enhances the capabilities of "The View" Hospital

On the sidelines of the exhibition, "Mazaya" Medical Trading Company signed a partnership agreement to supply "The View" Hospital with the necessary equipment in collaboration with "Elegancia Healthcare." This agreement is part of their efforts to introduce more developments to the hospital. The agreement was signed at the Baxter company booth in the presence of the General Manager of "Mazaya," Mr. Mohammed Ragheb, the CEO of "Elegancia," Mr. Joseph Hazel, the Chief Financial Officer of Elegancia company Anshul Nanda, and the Cluster Director procurement & supply chain Venu Isukapalli. This step confirms "Mazaya" Company's commitment to enhancing the capabilities of "The View" Hospital to ensure the provision of the best medical services to patients.

Revolutionary Technology for "The View" Hospital

The company also signed a contract with "The View" Hospital to introduce the first device for 3D Mapping and Electrophysiology in the

hospital's catheterization lab from Johnson & Johnson. This will contribute to providing the best medical services to patients, in a move that confirms the company's commitment to offering the best medical services. This technology allows doctors to see the heart in three dimensions, providing them with more precision and efficiency in both diagnosis and surgeries. The general manager of "Mazaya" expressed his delight in signing this contract, which represents an important step in the company's journey and its distinguished role in developing medical services in Qatar.

"MAZAYA" COMPANY

SHONE BY WINNING THE " GROWTH IN THE MIDDLE EAST" AWARD, REFLECTING THE COMPANY'S RELENTLESS AND CONTINUOUS EFFORTS IN ACHIEVING THE HIGHEST STANDARDS AND LEADERSHIP.

Mazaya & Elegancia: Beneficial Partnership Agreements

Mazaya & The "View" hospital ( J & J)

"Growth in the Middle East" Award

"Mazaya" Company shone by winning the "Growth in the Middle East" Award, reflecting the company's relentless and continuous efforts in achieving the highest standards and leadership. This award represents a culmination of the persistent and continuous efforts that the company has made over the years to achieve the highest standards and leadership in its field. "Mazaya" team expressed their pride and honor in this fantastic achievement, which confirms the company's commitment to providing the best services to its clients. The ceremony was attended by the Regional Manager of SECA, alongside the "Mazaya" team.

Collaboration with Al-Ahli Hospital

In a related development, the CEO of Al-Ahli Hospital in Qatar, Mr. Khaled Al-Emadi, and Deputy Chief Executive Officer Mr. Jamal Hammadi, visited the Mindray company booth during the Arab Health Exhibition. There, they agreed to introduce the latest ultrasound technology in the hospital and to conduct training courses on its use. Through this collaboration, "Mazaya" Company aims to provide the latest ultrasound technology in the State of Qatar and offer better diagnostic and therapeutic services to patients.

Latest Equipment for the New Military Hospital

The exhibition coincided with the opening of the new military medical hospital by the Qatar Ministry of Defense, attended by the Minister of Public Health, Dr. Hanan Al Kuwari, along with a large delegation from the Ministry of Defense. Here, the pivotal role played by "Mazaya" Company in equipping the new hospital was highlighted. The company provided modern medical furniture, operating room equipment, intensive care units, all medical beds from Baxter, all physical therapy and rehabilitation devices, as well as the latest hydrotherapy pool.

THE EXHIBITION COINCIDED WITH THE OPENING OF THE NEW MILITARY MEDICAL HOSPITAL BY THE QATAR MINISTRY OF DEFENSE, ATTENDED BY THE MINISTER OF PUBLIC HEALTH, DR. HANAN AL KUWARI, ALONG WITH A LARGE DELEGATION FROM THE MINISTRY OF DEFENSE. HERE, THE PIVOTAL ROLE PLAYED BY "MAZAYA" COMPANY IN EQUIPPING THE NEW HOSPITAL WAS HIGHLIGHTED.

Mazaya: "Growth in the Middle East" (SECA)

Mazaya & Al-Ahli Hospital

Accuhealth Offers a Personalized Approach to Chronic Care Management

Living with a chronic condition can be daunting, not just for patients but also for their loved ones. Juggling doctor’s appointments, managing medications, and navigating complex healthcare systems can leave families feeling overwhelmed and unsure of where to turn.

Chronic Care Management (CCM) offers a beacon of hope and support during these difficult times. CCM goes beyond traditional onesize-fits-all healthcare. It recognizes that each

individual's journey with a chronic condition is unique and takes a holistic view to address all of a patient’s care needs.

Accuhealth elevates this standard with a concierge-level CCM program. The robust solution provides patient care coordination, daily health and preventative medical assessments, and a 24/7/365 English- and Spanish-speaking clinical care team is available to them.

For families navigating the complexities of chronic care, Accuhealth's personalized approach to CCM offers more than just medical benefits. It

ACCUHEALTH'S INNOVATIVE APPROACH TO CCM REPRESENTS THE FUTURE OF CHRONIC CARE MANAGEMENT.

provides invaluable peace of mind, knowing that their loved ones are receiving the highest quality care. Accuhealth's innovative approach to CCM represents the future of chronic care management. By prioritizing personalization, Accuhealth is not only improving the lives of individuals living with chronic conditions but also transforming the healthcare landscape for the better.

Chronic Care Management 101

The United States is facing an unprecedented change in the healthcare landscape. Officials estimate that the number of people in the United States aged 50 years and older will increase by 61.11% from 137.25 million in 2020 to 221.13 million in 2050. Of that population, the number with at least one chronic disease is estimated to increase by 99.5% from 71.522 million in 2020 to 142.66 million by 2050. As an increasing number of individuals manage one or more long-term chronic conditions, CCM has emerged as a vital tool for optimizing patient outcomes and reducing healthcare costs. At its core, this model of care shifts the focus from reactive treatment to preventive management.

Defining Chronic Care Management

CCM goes beyond traditional healthcare by providing ongoing support and coordination for individuals living with two or more chronic conditions expected to last at least a year. This team-based approach often involves a doctor, nurse, care manager, and other healthcare professionals, who work collaboratively to develop and implement a customized care plan for each patient. This plan not only lists a patient’s health problems, but also includes medications, services, and other information that can be beneficial to managing their chronic conditions. Chronic conditions often require additional care beyond regular doctor’s visits. CCM, with its proactive, sustainable approach to care, is key to improving health outcomes for the aging population and providing families with the support they need.

Benefits of Chronic Care Management Programs

CCM programs are a collaborative effort between the healthcare team, patients, and their loved ones. Through teamwork, patients, families, and the healthcare system as a whole can reap the many benefits of this program.

Improve Patient Outcomes and Satisfaction

CCM helps patients better manage their chronic conditions, in large part by providing education to the patient about their conditions. This can lead to improved symptom control and reduced risks of hospitalization. By some estimates, the Chronic Care Model has guided quality improvement in healthcare for almost two decades. This individualized support tailored to a patient’s specific needs and goals ensures care needs are constantly being met, effectively reducing the need for hospitalization. ER visits and inpatient treatment are not only costly but can be detrimental to patient health.

Long inpatient visits can worsen patient outcomes as they disrupt sleep schedules and lead to many patients losing weight and muscle mass. This is especially true among elderly populations that experience “post-hospital syndrome” which leads to readmission at higher rates. While these visits are necessary to provide urgent care, oftentimes they are preventable. CCM offers a patient-centered, disease management approach which translates to a higher quality of life and increased sense of well-being among patients.

Reduce Healthcare Costs

Healthcare costs are rapidly increasing. For patients with chronic conditions, these costs are even more drastic. According to the most recent numbers, healthcare coverage costs for people with a chronic condition average $6,032 annually. To put that in perspective, that is five times higher than for those without such a condition. These costs can be a burden for patients and families alike. CCM prioritizes proactive care which can lead to fewer ER visits,

ACCUHEALTH IS DEDICATED TO PROVIDING HEALTHCARE SOLUTIONS THAT BENEFIT BOTH PATIENTS AND THEIR LOVED ONES. KNOWING A FAMILY MEMBER HAS DEDICATED SUPPORT AND GUIDANCE FROM A COMPASSIONATE CARE TEAM CAN PROVIDE THEM WITH SIGNIFICANT PEACE OF MIND.

hospitalizations, and other costly healthcare interventions to ease these expenses.

Enhance Patient Wellbeing

Healthcare, especially for chronic conditions, should extend long after an appointment. CCM programs often include medication management assistance to help patients stay on track with medications and avoid potential side effects.

Education and coordination go hand in hand at Accuhealth. Regular monitoring and communication with a compassionate and knowledgeable care team allow for timely adjustments to a patient’s treatment plan, preventing complications from getting worse.

Peace of Mind for Loved Ones

Knowing a family member has dedicated support and guidance from a compassionate care team can provide loved ones with significant peace of mind. At the same time, a CCM

program also helps alleviate the financial and emotional burden of being a caregiver. As stated before, these programs can drastically reduce healthcare costs. They also provide practical assistance and education on how families can be there in the best way for patients. This can include emotional support, such as connecting families to support groups or other community resources that can be beneficial.

Perhaps most important, however, is how CCM can facilitate better communication across a care community, creating an open line of communication between patients, their loved ones, and their entire care team.

This ensures everyone is on the same page regarding a treatment plan and enables the types of consistent care that chronic conditions require.

How Accuhealth Approaches CCM

In the crowded landscape of CCM programs, Accuhealth stands out by prioritizing quality of

THE TEAM AT ACCUHEALTH ALSO GOES ABOVE AND BEYOND TO ENSURE THE NEEDS OF PATIENTS ARE BEING MET. THE CONCIERGELEVEL SERVICE EXTENDS TO ASSISTING PATIENTS WITH FINDING AFFORDABLE MEDICATION, COUNSELING SERVICES, AND EVEN FOOD ASSISTANCE DEPENDING ON THEIR NEEDS.

care over quantity of visits. This patient-centric approach that focuses on deeper engagement and better outcomes sets them apart from the industry standard.

Lower Caseloads

At the end of the day, many CCM programs are driven by numbers. There’s an expectation to see a certain number of patients a day to meet quotas. Accuhealth champions smaller caseloads so that each patient receives dedicated attention and individualized care. This gives way to longer, more meaningful interactions that go beyond simply checking boxes. Patients truly connect and build trust with the Accuhealth team, improving their experience. This trust also goes a long way to enhancing health outcomes. Oftentimes, patients may open up about symptoms or have questions they have not brought up with their doctor. They trust the Accuhealth team for the proper support and can have their concerns addressed right away rather than waiting for their next appointment.

Value and Quality Driven

As stated before, Accuhealth's commitment goes beyond just meeting the quota. Their focus is on delivering the best possible care for each patient, driving positive health outcomes and improved quality of life. This value-based approach ensures resources are invested in interventions that truly make a difference.

This commitment to quality extends beyond what is traditionally included in a CCM program. With Accuhealth, patients can expect concierge care coordination, preventative medical assessments, a 24/7/365 clinical care team available to them, intimate health coaching, and motivation. Telemedicine and remote monitoring, including psychological monitoring, are also offered so patients can be empowered to manage their

chronic conditions from the comfort of their homes. The team at Accuhealth also goes above and beyond to meet the needs of patients. The concierge-level service extends to assisting patients with finding affordable medication, counseling services, and even food assistance depending on their needs. CCM is never a onesize-fits-all solution, and at Accuhealth it is never treated as such.

Patient-First Scheduling

Accuhealth schedules visits based on individual patient needs, not rigid schedules. While there are certainly always follow-up visits and yearly physicals every patient should go to, those with chronic conditions often require more frequent, flexible medical appointments. Accuhealth is available to patients when they need it most, not just when the calendar dictates. This is a key factor in providing proactive healthcare and is crucial for managing chronic conditions effectively.

High Adherence Rates

The proof speaks for itself: Accuhealth boasts an impressive 86% adherence rate among patients. Their personalized approach to CCM ensures patients continuously receive the care they need beyond a doctor’s office. This translates to better-controlled chronic conditions and fewer complications – which in turn reduces the risk of hospitalizations.

At Accuhealth, healthcare is about building relationships, not racking up numbers. By prioritizing quality interactions and a patient-centric approach, Accuhealth is truly delivering what a CCM program should be, a collaborative journey toward optimal health outcomes for individuals living with chronic conditions.

Learn more about Accuhealth and their concierge value-based CCM https://www.accuhealth.tech/chronic-care-management

For more information, please visit www.accuhealth.tech/MIDDLE-EAST-ENG

ACCUHEALTH CHAMPIONS

SMALLER

CASELOADS, ENSURING EACH PATIENT RECEIVES DEDICATED ATTENTION AND INDIVIDUALIZED CARE. THIS ALLOWS FOR LONGER, MORE MEANINGFUL INTERACTIONS THAT GO BEYOND SIMPLY CHECKING BOXES. THESE QUALITY INTERACTIONS ALLOW PATIENTS TO TRULY CONNECT AND BUILD TRUST WITH THE ACCUHEALTH TEAM, IMPROVING THEIR EXPERIENCE.

Redefining Women's Healthcare: A Glimpse into Our Gynecology Department's Dedication to Luxury, Safety, and Expertise

Dr. Maysa Khadra, Consultant IVF and OBG Head of Department at Al-Ahli Hospital/Qatar

In the realm of women's healthcare, our Gynecology Department stands as a beacon of excellence, committed to providing a healthcare experience that transcends the ordinary. Nestled within our healthcare facility, this department embodies a fusion of luxury, safety, and expertise, redefining the standards of care for women of all ages.

Luxurious Suites: Where Comfort Meets Care

As you step into our Gynecology Department, you are greeted by an ambiance of tranquility and comfort. Our suites are meticulously designed to offer a sense of relaxation and serenity, alleviating any apprehensions or anxieties associated with medical visits. From plush furnishings to soothing décor, every element is curated to ensure your utmost comfort throughout your time with us.

We recognize that women's health is deeply intertwined with their sense of well-being, and our luxurious suites serve as a testament to our commitment to addressing both physical and emotional needs in equal measure.

Safety First: Nurturing a Secure Environment

Amidst the backdrop of luxury, safety remains paramount in our Gynecology Department. We uphold rigorous standards of cleanliness and hygiene, implementing stringent protocols to safeguard the health and well-being of our patients.

Our team of dedicated healthcare professionals is unwavering in their commitment to maintaining a safe environment, conducting regular sanitation procedures and adhering to stringent infection control measures. Your safety is our priority, and we spare no effort in ensuring

that every visit to our department is met with the highest standards of hygiene and protection.

Expert Care: Guiding You with Compassion and Expertise

At the core of our Gynecology Department lies a team of seasoned medical professionals, each dedicated to providing personalized care tailored to your unique needs. Our boardcertified gynecologists and obstetricians bring a wealth of experience and expertise to every interaction, ensuring that you receive the highest quality of care at every turn.

Conclusion: A Sanctuary for Women's Health and Wellness

Our Gynecology Department offers women a sanctuary for comprehensive care in a luxurious, safe, and expert environment, prioritizing your health and well-being at every step.

WE UPHOLD RIGOROUS STANDARDS OF CLEANLINESS AND HYGIENE, IMPLEMENTING STRINGENT PROTOCOLS TO SAFEGUARD THE HEALTH AND WELLBEING OF OUR PATIENTS.

Advancements in Fertility Care Led to Remarkable Success Rates in 2023

In 2023, our fertility department celebrated a significant milestone with a remarkable success rate of 54%, underscoring our unwavering commitment to excellence in fertility care. This achievement is a testament to the transformative impact of personalized treatment plans, innovative hormonal stimulation protocols, and cutting-edge techniques employed by our dedicated team of experts.

Personalized Treatment Plans

One of the cornerstones of our success lies in our personalized treatment approach, tailored to each patient's unique needs and circumstances.

By meticulously analyzing factors such as age, medical history, and genetic profile, we're able to craft individualized treatment plans that optimize the effectiveness of IVF procedures. This tailored approach not only increases success rates but also reduces the time to conception, offering hope and reassurance to our patients.

Special Hormonal Stimulation Protocols

Our commitment to staying at the forefront of fertility care is evident in our adoption of special hormonal stimulation protocols. By incorporating advancements such as gonadotropin-releasing hormone (GnRH) agonists and antagonists, we've been able to optimize ovarian response, minimize risks, and significantly increase success rates in IVF cycles. This forward-thinking approach ensures that our patients receive the most effective and safest treatment possible.

Cutting-Edge Techniques

At the heart of our success lies our investment in cutting-edge IVF technology. Techniques such as using embryo glu, assisted hatching and preimplantation genetic testing (PGT) when needed have revolutionized our

approach to embryo selection, leading to a marked increase in success rates.

Improved Lab Conditions

Our state-of-the-art laboratory facilities play a pivotal role in our success, providing the optimal environment for embryo development. With advancements in controlled atmosphere systems, improved culture media, and specialized equipment including the newest embryo incubators , ICSI and micromanipulators, we ensure the viability of embryos and consistently achieve high success rates. Our commitment to maintaining the highest standards of care extends to every aspect of our practice, ensuring the best possible outcomes for our patients.

Cryopreservation Techniques

Another key factor contributing to our success is the impact of advanced cryopreservation techniques. Vitrification, in particular, has revolutionized the preservation of embryos and oocytes, allowing for improved timing of embryo transfer and increased success rates in frozen embryo transfer (FET) cycles. This breakthrough technology offers our patients greater flexibility and improved outcomes in their fertility journey.

Patient Support and Counseling

We recognize that undergoing fertility treatment can be emotionally challenging, which is why we prioritize comprehensive patient support and counseling programs. From emotional support and stress reduction techniques to lifestyle interventions, we provide our patients with the tools and resources they need to optimize IVF outcomes and achieve higher success rates. Our compassionate team is dedicated to guiding and supporting our patients every step of the way, ensuring they feel empowered and informed throughout their fertility journey.

In conclusion, our department's remarkable success rate in 2023 is a testament to our unwavering dedication to excellence, innovation, and patient-centered care. By leveraging personalized treatment plans, innovative techniques, and compassionate support, we continue to redefine the standards of fertility care and help our patients realize their dreams of parenthood. As we look to the future, we remain committed to advancing the field of fertility care and empowering individuals and couples to build their families with confidence and hope.

Cancer Detection: Essential Steps from Screening to Diagnosis

Diagnostic tests play a crucial role in identifying the presence, type, stage, and spread of cancer, enabling the necessary therapeutic measures and the development of an effective and personalized treatment plan for the patient. These tests are conducted as needed after consulting with healthcare providers and are necessary steps for early cancer detection, thereby activating prevention strategies.

While laboratory tests and diagnostic imaging can aid in early detection, they are not definitive tests. In cases where evidence or results related to cancer or any other medical condition are found, further diagnostic tests, such as imaging scans or biopsy, may be required to confirm a cancer diagnosis. It's important to note that the choice of diagnostic tests depends on multiple factors, such as the suspected type of cancer, tumor location, the patient's overall health condition, age, medical history, and family history. Healthcare professionals will use clinical results and the patient's medical history to determine the most suitable tests.

Laboratory Tests: The First Warning Signs

Complete Blood Count (CBC)

Measuring various types of blood cells, including red blood cells, white blood cells, and platelets. Imbalances in these blood cell counts can sometimes indicate the presence of certain types of cancers, such as leukemia or lymphoma.

Blood Chemistry Tests

These tests measure different substances and chemicals in the blood, like electrolytes, liver and kidney function markers, and tumor markers, which are substances produced by cancer cells or by normal cells in response to cancer. Elevated levels of some tumor markers may indicate the presence of specific types of cancer

. Urine Test

Involves analyzing a urine sample for abnormalities, such as the presence of blood, protein, or abnormal cells, providing insights into specific types of cancers like bladder or kidney cancer.

Pap Smear

A screening test for cervical cancer in women. It involves collecting cells from the cervix and examining them for any changes or abnormal signs of pre-cancerous or cancerous cells.

Prostate-Specific Antigen (PSA) Test

Used to screen for prostate cancer in men. It measures PSA levels, a protein produced by the prostate gland. Elevated PSA levels may indicate the presence of prostate cancer, though further diagnostic tests are needed for confirmation.

Mammography

X-ray imaging of breast tissues used to screen for breast cancer in women. It can detect abnormalities, such as tumors or calcifications, requiring further investigation.

Medical Imaging Techniques: Clear Insights from Within

After detecting a health issue indicating the possibility of cancer through routine screening tests, doctors then proceed to additional diagnostic tests to confirm the cancer diagnosis. These tests provide more detailed information about the presence, location, and extent of cancer. CT scans and X-rays are used to create detailed images of the body, helping in tumor identification. Patients undergo MRI, where magnetic fields and radio waves measure the tumor's size and extent. Ultrasound images of organs and tissues help in evaluating the tumor's characteristics. Positron Emission Tomography (PET) scans involve injecting radioactive substances into the body to detect the presence and spread of cancer.

Common Diagnostic Tests for Cancer Include:

Computed Tomography (CT) Scan:

Produces a comprehensive cross-sectional image of the body using X-rays, helping in locating cancers and determining their size.

Magnetic Resonance Imaging (MRI):

WHILE LABORATORY TESTS AND DIAGNOSTIC IMAGING CAN AID IN EARLY DETECTION, THEY ARE NOT DEFINITIVE TESTS. IN CASES WHERE EVIDENCE OR RESULTS RELATED TO CANCER OR ANY OTHER MEDICAL CONDITION ARE FOUND, FURTHER DIAGNOSTIC TESTS, SUCH AS IMAGING SCANS OR BIOPSY, MAY BE REQUIRED TO CONFIRM A CANCER DIAGNOSIS.

Generates detailed images of the body by combining radio waves and magnetic fields. It's particularly useful for imaging soft tissues and can provide information about the size and spread of malignant tumors.

Ultrasound:

Generates images of internal organs and tissues using sound waves. It helps in determining the tumor's characteristics and is evaluated by a radiology specialist and the treating physician.

Positron Emission Tomography (PET) Scan:

Involves injecting a small amount of radioactive material into the body, absorbed by rapidly growing cells, such as cancer cells.

Biopsy:

A crucial procedure for accurate cancer diagnosis, though it does not constitute the sole basis for diagnosis. The doctor must be consulted to determine the appropriate type of biopsy based on the health condition, symptoms, and other tests. A biopsy is a medical procedure where a small sample of tissues or cells is taken from the suspected tumor or affected area. The sample is then examined under a microscope to determine the presence of cancer cells. Types of biopsies include:

• Needle Biopsy: Uses a needle to extract a tissue or fluid sample from a suspected area, guided by imaging techniques like ultrasound or CT scan.

• Surgical Biopsy: Involves a surgical operation to remove a larger part or the entire tumor for examination.

• Endoscopic Biopsy: Uses an endoscope to take tissue samples from the digestive system, respiratory system, and other body cavities.

Immunohistochemistry (IHC):

Analysis uses specific antibodies to detect proteins or other markers on cancer cells. Immunohistochemistry helps in determining the type of cancer and guiding the doctor towards the best treatment options.

Molecular Tests:

Involve analyzing DNA, RNA, or other genetic changes in cancer cells. These tests can predict the patient's response to treatment and choose more precise targeted therapies. These techniques offer greater accuracy in diagnosis compared to traditional methods and the ability to more specifically identify the type of cancer, helping guide the doctor toward personalized treatment options for each cancer type.

IT'S IMPORTANT TO NOTE THAT THE CHOICE OF DIAGNOSTIC TESTS DEPENDS ON MULTIPLE FACTORS, SUCH AS THE SUSPECTED TYPE OF CANCER, TUMOR LOCATION, THE PATIENT'S OVERALL HEALTH CONDITION, AGE, MEDICAL HISTORY, AND FAMILY HISTORY. HEALTHCARE PROFESSIONALS WILL USE CLINICAL RESULTS AND THE PATIENT'S MEDICAL HISTORY TO DETERMINE THE MOST SUITABLE TESTS

ARTICLES

‘Beyond Everyday’: Specialist Infusion Management

Ece Aydinc. RN. Becton Dickinson. Clinical Resource Consultant, Medication Management Solutions, Turkey.

Samuel Garcia. RN, BHSc. Becton Dickinson. Medical Affairs Director, Medication Management Solutions, Europe, Middle East and Africa..

James Waterson. RN, MMedEd. MHEc. Becton Dickinson. Senior Medical Affairs Manager, Medication Management Solutions, Middle East & Africa.

Tina Worth. HV, RGN, LLM, MBA. Becton Dickinson. Senior Medical Affairs Manager, Medication Management Solutions, Europe, Middle East and Africa.

As Medical Affairs and Clinical Professionals working in the field of infusion and medication safety, we are often asked about some of the more specialist uses of infusion therapy and infusion pumps. Not every IV-therapy is a simple maintenance infusion of Normal Saline!

Subcutaneous Infusion

Subcutaneous infusion administration has been around as a therapy for a very long period of time, but it has attracted a great deal more interest recently.

Continuous Subcutaneous Infusion (CSCI) delivered by syringe pump is a useful administration method in pain management.1 There is evidence that drug therapy with continuous subcutaneous infusions (CSCI) over 24 to 48 hours has several benefits, both in patient care and in the application of healthcare resources.2

Beyond this, the scope for CSCI to deliver other medications, therapies, and intravenous fluids for hydration has expanded to manage situations such as venous depletion, and practice recommendations for subcutaneous infusions of fluids and medications have been developed.3 Among the recommendations for Assessment, Best Practice, and Competency are:

• Assess the intended duration of therapy, reasons for using the parenteral route, the properties of the solution/medication, and the patient's clinical, tissue, and skin condition.

• Complete an interprofessional team hydration/nutrition/electrolyte

assessment to determine the patient's fluid and electrolyte needs.

• Review the medication product monograph to determine suitability.

• Ensure that subcutaneous medications and hydration prescribed are at rates, frequency, and volumes/dosage appropriate for the patient's age, weight, clinical condition, individual subcutaneous absorption, laboratory values, and as recommended by the drug manufacturers or supporting literature, and generally not exceeding those used for IV infusions.

• Avoid infusion rates >5 mL/h for medications (unless recommended by manufacturer, eg, subcutaneous immunoglobulin). Slow infusion rates and use of diluted solutions have been recommended in the literature for subcutaneous antibiotics.

• Select a site for subcutaneous access with intact skin and adequate subcutaneous tissue (eg, minimum 1.0-

CONTINUOUS SUBCUTANEOUS INFUSION (CSCI) DELIVERED BY SYRINGE PUMP IS A USEFUL ADMINISTRATION

METHOD IN PAIN MANAGEMENT. 1 THERE IS EVIDENCE THAT DRUG THERAPY WITH CONTINUOUS SUBCUTANEOUS INFUSIONS (CSCI) OVER 24 TO 48 HOURS HAVE SEVERAL BENEFITS, BOTH IN PATIENT CARE AND IN THE APPLICATION OF HEALTHCARE RESOURCES.2

Specialist subcutaneous infusion devices such as the BD Saf-TIntimTM Safety System are designed to optimize subcutaneous therapy. In certain clinical situations where IV access is not required, possible or practical, subcutaneous infusions can be a safe alternative.4

2.5 cm thickness).

• Consider use of 2 or more sites as required for high-volume solutions.

Subcutaneous infusion offers several advantages over intravenous infusion, including ease of application, lower costs, and a lack of potential serious complications, particularly infections. Subcutaneous infusion may be of particular value in patients with mild to moderate dehydration or malnutrition.4

Regional Analgesia or ‘Nerve Block’ Infusions

In terms of delivering analgesia to meet acute pain needs both peri-operatively and postsurgery, Regional Nerve Block infusion analgesia delivered via smart analgesia pumps is beginning to show significant advantages over general anesthesia and traditional peri-operative and post-operative analgesia regimes.

In one recent study patients undergoing upper limb surgeries showed significantly higher satisfaction scores than those who received general anesthesia5 and the technique has been preferred at other centres for lower limb surgery as it has lower operating room duration per case than general anesthesia6 with results comparable to general anesthesia for pain control.

In addition to employing pre-prepared nerve block trays, practitioners should consider the use of clearly labelled infusion lines for regional infusions. 7

In terms of patient safety, the technique can be useful for patients who might be considered to be high risk for respiratory depression with parental analgesia.

The Faculty of Pain Medicine of the United Kingdom recommends the use of grey tubing to differentiate regional infusions from other infusion routes.7

Epidural Infusions:

To reduce the risk of incorrect connections and injections the ISO 80369 series of standards was issued in 2016. It defines a separate, incompatible connection for epidural and regional block anesthesia and analgesia.

In simple terms, an intravenous administration line or standard syringe will not fit an NRFit® epidural cannula, and an NRFit® epidural administration set will not fit onto an intravenous cannula.

Epidural administration line safety goes beyond the connector, however. The Institute for Safe Medication Practices (ISMP) state that facilities should always, ‘use yellow-lined tubing without injection ports for epidural infusions to set its appearance apart from typical IV tubing, and never use yellow-lined tubing for anything other than epidural administration.’8

The Faculty of Pain Medicine of the United Kingdom in its ‘Best Practice in the Management of Epidural Analgesia in the Hospital Setting’ recommends the use of yellow tubing to differentiate epidural/spinal lines from arterial (red), enteral (purple) and regional (grey) infusions.7

It is usual for facilities to set preprogrammed epidural therapy protocols for maternity units and for surgical units. Each protocol would specify background rate, lockout time and patient bolus, clinician bolus and PIEB (Programmed Intermittent Epidural Bolus). The protocols are commonly set as total dose per hour, and can be set as weight-based, by dose/kg.

Extra boluses may be delivered at the clinician’s discretion, with soft and hard dose limits applied to these doses and to the background rate, patient doses, and any PIEB settings.

SUBCUTANEOUS INFUSION

OFFERS SEVERAL ADVANTAGES OVER INTRAVENOUS INFUSION, INCLUDING EASE OF APPLICATION, LOWER COSTS, AND A LACK OF POTENTIAL SERIOUS COMPLICATIONS, PARTICULARLY INFECTIONS.

SUBCUTANEOUS INFUSION MAY BE OF PARTICULAR VALUE IN PATIENTS WITH MILD TO MODERATE DEHYDRATION OR MALNUTRITION.4

Smart Epidural pumps are capable of delivering bespoke therapy protocols with specific settings for background rate, lockout time and patient bolus, clinician bolus, and PIEB (Programmed Intermittent Epidural Bolus).

In PIEB the pump delivers an intermittent dose of analgesia on a set cycle, whilst maintaining the background infusion and allowing patient boluses which are regulated by a lockout period. There have been some studies that indicate shorter duration of maternal labor and improved patient satisfaction with PIEB.9

The theory behind PIEB is that the automated bolus improves the spread of anesthetic solution within the epidural space, and therefore enhances the sensory blockade.10

Arterial Line, Pulmonary Artery, and Right Atrial Line Maintenance, and Flush Options

In many adult intensive care units pressurized flush bags are used to deliver approximately 3ml/hr of flush of normal saline per catheter to maintain the patency of arterial lines and central venous catheters. These bags require attention to maintain the pressure bag at the required 300 mm Hg of pressure.11, deviation from this setting may affect flow. Using IV syringe pumps to deliver these specialist catheter maintenance infusions will give a documented accuracy for the volumes delivered and may require fewer nursing interventions

to maintain flush patency. The use of syringe drivers at rates of 0.5-1 ml/hr to maintain specialist line patency has been a common practice in neonatal and pediatric critical care for a considerable period of time.

Flushing of the catheter after blood sampling can be achieved with pre-set handsfree boluses delivered via the pump and from within the medication library. Flush solutions can also be added to barcode medication administration (BCMA) libraries and order strings to help ensure ‘right patient- right medication’ processes are maintained.

There have been reported ‘wrong medication’ instances of inappropriate fluids such as glucose being inadvertently administered via arterial lines.12 BCMA could help to substantially reduce this risk.

FLUSHING OF THE CATHETER AFTER BLOOD SAMPLING CAN BE ACHIEVED WITH PRE-SET HANDS-FREE BOLUSES DELIVERED VIA THE PUMP AND FROM WITHIN THE MEDICATION LIBRARY.

Flushing of arterial and central line transducer sets after blood sampling can be achieved with pre-set hands-free boluses delivered via the pump and from within the medication library

Smart pumps with multistep functions can undertake necessary rate changes automatically at pre-programmed intervals for medications such as IVIG, giving the nurse more time to concentrate on the patient’s condition.

Multistep Infusion Administration

Intravenous immunoglobulin (IVIG) is a biological agent used to manage autoimmune, infectious, and inflammatory conditions. Patients receiving initial (first-time) IVIG infusions and high-risk patients should be monitored carefully for any infusion-related reactions or adverse effects.

Generally, the infusion rate commences at a rate of 0.5 to 1 mL/kg/hour for the first 15 to 30 minutes, and if no adverse reaction occurs, then the rate can be increased subsequently every 15 to 30 minutes to a maximum of 3 to 6 ml/ kg/hour, though this regimen is also dependent on the individual medication manufacturer’s instructions for use.13 This process can be very labor-intensive and adds to the nursing workload- the nurse must check the patient’s condition at each interval before allowing the rate to be increased.

Multistep infusions undertake the necessary rate change automatically at pre-programmed intervals, this can release the nurse from programming each step and allow them to concentrate on the patient’s condition, vital signs, and comfort.

‘Ramping’

The optimal blood glucose target for patients in the intensive care unit has not been definitively defined, but a target of 140 to 180 mg/dL (7.8-10 mmol/L) has been accepted by most critical care societies worldwide.14

‘Stress hyperglycemia’ in the critically ill patient can be caused by excessive counterregulatory hormones such as corticosteroid, glucagon, growth hormone, and catecholamines, and the release of cytokines such as tumor necrosis factor (TNF)-alpha and interleukin (IL)-1.

These factors can promote transient insulin resistance that can lead to decreased insulin action on suppressing gluconeogenesis and also to decreased uptake of insulin-mediated skeletal muscle glucose.15

Hyperglycemia is also aggravated by medications such as steroids and catecholamines, parenteral nutrition, and intravenous medications diluted in dextrose.16

This insulin resistance can be particularly important during the beginning and ending of infusions of total Parenteral Nutrition (TPN) as the glucose load of the infusion can be expected to raise the blood glucose level, but the insulin

The ramping effect in TPN programs available in some infusion pumps can give time for the physiological response to ‘catch up’ with a more slowly rising glucose load.

EPIDURAL ADMINISTRATION LINE SAFETY GOES BEYOND THE CONNECTOR, HOWEVER. THE INSTITUTE FOR SAFE MEDICATION PRACTICES (ISMP) STATE THAT FACILITIES SHOULD ALWAYS, ‘USE YELLOW-LINED TUBING WITHOUT INJECTION PORTS FOR EPIDURAL INFUSIONS TO SET ITS APPEARANCE APART FROM TYPICAL IV TUBING, AND NEVER USE YELLOW-LINED TUBING FOR ANYTHING OTHER THAN EPIDURAL ADMINISTRATION.’8

response to normalize the blood glucose is inhibited. The ramping effect in TPN programs available in some infusion pumps can give time for the physiological response to ‘catch up’ with a more slowly rising glucose load.

Furthermore, these programs can also ‘ramp down’ to allow the blood glucose to fall in a more controlled fashion at the end of the TPN infusion and to give more time for physiological mediators to achieve normoglycemia.

Radioactive Isotope Intravenous Administration

Lutetium-177 (Lu-177) is a medical isotope used in targeted radionuclide therapy for treating neuroendocrine tumors and prostate cancer. It is currently the most commonly used isotope for targeted radionuclide therapy.

It can be intravenously administered and one set of authors noted that whilst, ‘the gravity infusion method is cost-effective, we identified some challenges that increased the possibility for error, contamination, and excessive radiation exposure.’17

Use of an infusion pump and protocol was found to ‘reduce error, the possibility of contamination, and most importantly radiation exposure.’ Lu-177 has a radioactive half-life of 6.5 Days 18 so if the frequency of use of Lu-177 treatments is more frequent than this then it is practical to treat the intravenous pump as effectively always at risk of radioactive contamination. General management should include the use of one infusion pump dedicated solely for Lu-177 administration, with the pump clearly labelled as a Lu-177 pump.

In the case of wireless networking, it can be of value to either disable the wireless on this pump and limit the medication library on the pump to Lu-177 only or to create a single pump network configuration only for pumps used with isotopes. Users can build a local library for the Lu-177 pump with duration and volume / dose as this can make programming set-up time shorter (with less risk of exposure for staff) but ml/hr program may be used if this is found to be simpler and quicker. Each infusion administration set should be disposed of as per local policy for radioactive disposables.

Intravenous administration of radioactive isotopes such as Lutetium-177 (Lu-177) via infusion pumps was found, in one study, to ‘reduce error, the possibility of contamination, and most importantly radiation exposure.’ 17

Administration of Blood Stem Cell Products

Previously cryopreserved, peripheral blood stem cell products are administered intravenously. The administration should be rapid (less than 30 minutes per unit) to reduce cellular damage caused by dimethyl sulfoxide exposure after thawing.19 Cells are typically thawed at the bedside and infused by gravity through a high-flow rate central venous catheter. It has been common practice to infuse the cells either by gravity or via a manual syringe push. A 2018 study raised concerns over these practices as the time for infusion can vary substantially with the gravity infusion method, and transfer of the stem cell product to a syringe potentially increases the risk of product contamination. Manual syringe pushes also increase the risk of excess variation in vein pressure during administration.19

The 2018 study compared the use of a volumetric pump to the use of gravity.

IN MANY ADULT INTENSIVE CARE UNITS PRESSURIZED FLUSH BAGS ARE USED TO DELIVER APPROXIMATELY 3ML/HR OF FLUSH OF NORMAL SALINE PER CATHETER TO MAINTAIN THE PATENCY OF ARTERIAL LINES AND CENTRAL VENOUS CATHETERS. THESE BAGS REQUIRE ATTENTION TO MAINTAIN THE PRESSURE BAG AT THE REQUIRED 300 MM HG OF PRESSURE.11

Infusion of stem cells is most commonly undertaken under the direction of a physician and rates may be adjusted according to the patient’s toleration of the therapy. This is more easily and accurately managed with an infusion pump than with gravity. A 2018 study found no significant difference in clinically important variables between patients who received stem cells via a pump and those who received them via gravity

The research team found that the infusion pump delivered more consistently within the prescribed time of administration, with 20% of the products infused by gravity having incorrect infusion rates of less than 2.5 mL/min, compared with only 5% for products infused by infusion pump. During the study, unusually slow infusion rates for two transfusions via gravity required the transfer of the product to a syringe at the patient’s bedside.

The infusion pump provided a controlled infusion for both small and large volume transfusions, without the need for transfer to syringes.

Infusion of stem cells is most commonly undertaken under the direction of a physician and rates may be adjusted according to the patient’s toleration of the therapy. This is more easily and accurately managed with an infusion

pump than with gravity.

In the 2018 study, in the two groups of patients who received stem cells via pump and via gravity no significant differences were seen between the two methods for measured clinically important variables such as Trypan Blue and Total Nucleated Cells. The study’s authors concluded that infusion pumps can be used safely for thawed stem cell products, and that infusion by pump can provide a reliable and consistent infusion and eliminate the need to transfer products to syringes.19

Off-Label Warnings

Healthcare professionals are always looking for new and imaginative ways to improve care, increase efficiency, and improve workflows. However, BD infusion pumps, as medical devices, have defined uses laid out in their Instructions

INTRAVENOUS IMMUNOGLOBULIN (IVIG) IS A BIOLOGICAL AGENT USED TO MANAGE AUTOIMMUNE, INFECTIOUS, AND INFLAMMATORY CONDITIONS. PATIENTS RECEIVING INITIAL (FIRST-TIME) IVIG INFUSIONS AND HIGH-RISK PATIENTS SHOULD BE MONITORED CAREFULLY FOR ANY INFUSION-RELATED REACTIONS OR ADVERSE EFFECTS. GENERALLY, THE INFUSION RATE COMMENCES AT A RATE OF 0.5 TO 1 ML/KG/HOUR FOR THE FIRST 15 TO 30 MINUTES, AND IF NO ADVERSE REACTION OCCURS, THEN THE RATE CAN BE INCREASED SUBSEQUENTLY EVERY 15 TO 30 MINUTES TO A MAXIMUM OF 3 TO 6 ML/KG/HOUR, THOUGH THIS REGIMEN IS ALSO DEPENDENT ON THE INDIVIDUAL MEDICATION MANUFACTURER’S INSTRUCTIONS FOR USE.13

ARTICLES

There are multiple specialist uses for infusion devices, but any use of such a device beyond the indications laid out in the Instructions For Use requires discussion with the respective department of Medical Affairs

For Use. Any use of the device beyond these specific use cases requires discussion with the respective department of BD Medical Affairs.

References:

Please feel free to reach out via your local BD representative to contact your regional BD Medical Affairs Department.

BD INFUSION PUMPS, AS MEDICAL DEVICES, HAVE DEFINED USES LAID OUT IN THEIR INSTRUCTIONS FOR USE.

1. Dickman A, Bickerstaff M, Jackson R, Schneider J, Mason S and Ellershaw J, Identification of drug combinations administered by continuous subcutaneous infusion that require analysis for compatibility and stability, Dickman et al. BMC Palliative Care. 2017.

2. Baker J, Dickman A, Mason S, Bickerstaff R, McArdle A, Lawrence I, Stephenson F, Paton N, Kirk J, Waters B and Ellershaw J, An evaluation of continuous subcutaneous infusions across seven NHS acute hospitals: is there potential for 48-hour infusions? BMC Palliative Care. 2020.

3. Broadhurst D, Cooke M, Sriram D, Barber L, Caccialanza R, Danielsen MB, Ebersold SL, Gorski L, Hirsch D, Lynch G, Neo SH, Roubaud-Baudron C, Gray B. International Consensus Recommendation Guidelines for Subcutaneous Infusions of Hydration and Medication in Adults: An e-Delphi Consensus Study. J Infus Nurs. 2023 Jul-Aug 01;46(4):199-209. doi: 10.1097/NAN.0000000000000511. PMID: 37406334; PMCID: PMC10306332.

4. Caccialanza R, Constans T, Cotogni P, Zaloga GP, Pontes-Arruda A. Subcutaneous Infusion of Fluids for Hydration or Nutrition: A Review. JPEN J Parenter Enteral Nutr. 2018 Feb;42(2):296-307. doi: 10.1177/0148607116676593. Epub 2017 Dec 20. PMID: 29443395.

5. Suresh P, Mukherjee A. Patient satisfaction with regional anaesthesia and general anaesthesia in upper limb surgeries: An open label, cross-sectional, prospective, observational clinical comparative study. Indian J Anaesth. 2021 Mar;65(3):191-196. doi: 10.4103/ija.IJA_1121_20. Epub 2021 Mar 13. PMID: 33776108; PMCID: PMC7989486.

6. Neal-Smith G, Hopley E, Gourbault L, Watts DT, Abrahams H, Wilson K, Athanassoglou V. General Versus Regional Anaesthesia for Lower Limb Arthroplasty and Associated Patient Satisfaction Levels: A Prospective Service Evaluation in the Oxford University Hospitals. Cureus. 2021 Aug 9;13(8):e17024. doi: 10.7759/cureus.17024. PMID: 34522505; PMCID: PMC8425506.

7. https://fpm.ac.uk/sites/fpm/files/documents/2020-09/Epidural-AUG-2020-FINAL.pdf

8. https://www.ismp.org/resources/epidural-iv-route-mix-ups-reducing-risk-deadly-errors

9. George RB, Allen TK, Habib AS. Intermittent epidural bolus compared with continuous epidural infusions for labor analgesia: a systematic review and meta-analysis. Anesth Analg. 2013 Jan;116(1):133-44. doi: 10.1213/ANE.0b013e3182713b26. Epub 2012 Dec 7. Erratum in: Anesth Analg. 2013 Jun;116(6):1385. PMID: 23223119.

10. Riley ET, Carvalho B. Programmed Intermittent Epidural Boluses (PIEB) for Maintenance of Labor Analgesia: A Superior Technique to Continuous Epidural Infusion? Turk J Anaesthesiol Reanim. 2017 Apr;45(2):65-66. doi: 10.5152/TJAR.2017.09031. Epub 2017 Apr 1. PMID: 28439433; PMCID: PMC5396898.

11. McGee, W, Young, C., Frazier, J. (Eds.). (2018). Edwards clinical education: Quick guide to cardiopulmonary care (4th ed.). Retrieved September 9, 2022, from https://education. edwards.com/quick-guide-to-cardiopulmonary-care-4th-edition/220356#

12. https://www.baccn.org/static/uploads/resources/HSIB_The_use_of_an_appropriate_flush_fluid_with_arterial_lines_Report.pdf

13. Kareva L, Mironska K, Stavric K, Hasani A. Adverse Reactions to Intravenous Immunoglobulins - Our Experience. Open Access Maced J Med Sci. 2018 Dec 20;6(12):2359-2362.

14. Alhatemi G, Aldiwani H, Alhatemi R, Hussein M, Mahdai S, Seyoum B. Glycemic control in the critically ill: Less is more. Cleve Clin J Med. 2022 Apr 1;89(4):191-199. doi: 10.3949/ ccjm.89a.20171. PMID: 35365557. DOI: https://doi.org/10.3949/ccjm.89a.20171

15. Corathers SD, Falciglia M. The role of hyperglycemia in acute illness: supporting evidence and its limitations. Nutrition 2011; 27(3): 276–281. doi:10.1016/j.nut.2010.07.013

16. McCowen KC, Malhotra A, Bistrian BR. Stress-induced hyperglycemia. Crit Care Clin 2001; 17(1):107–124. doi:10.1016/s0749-0704(05)70154-8

17. Davis A, Pietryka M, Passalaqua S. Technical Aspects and Administration Methods of 177Lu-DOTATATE for Nuclear Medicine Technologists. J Nucl Med Technol. 2019 Dec;47(4):288-291. doi: 10.2967/jnmt.118.221846. Epub 2019 Apr 24. PMID: 31019033.

18. Nuclide Safety Data Sheet: Lutetium-177 www.nchps.org

19. Reich-Slotky R, Cushing M, Hsu Y, Ancharski M, Rojas J, Scrimenti L, Robilio S, Assalone D, Roselli T, Guarneri D, Vasovic L, Goel R, Shore T, van Besien K. Validating and implementing the use of an infusion pump for the administration of thawed hematopoietic progenitor cells-a single-institution experience. Transfusion. 2018 Feb;58(2):339-344. doi: 10.1111/trf.14409. Epub 2017 Nov 29. PMID: 29193156.

Kidney Stones Diet

Afia’a Mohammed Al Masri, Chief Dietician at Al-Ahli Hospital/Qatar

Purpose

The kidneys' main function is to filter the blood to remove excess mineral salts and other soluble wastes. Also they produce the urine that dissolves these wastes and excretes them through the urinary tract. Kidney stones form when the urine becomes so saturated with a certain mineral that no more of it can dissolve into the urine. The undissolved portion of the mineral forms crystals that then clump together and grow into hard stones. Kidney stones usually develop in the kidneys. However they can form anywhere in the urinary tract. This condition is medically known as urolithiasis or nephrolithiasis.

When kidney stones are quite tiny, they may pass unnoticed with the urine. Often however, they grow too large to pass easily through the urinary tract, and some stones have rough or sharp edges. When these stones are passing through the urinary tract, it can be quite painful. In some cases, kidney stones cannot pass on their own, and treatment with specialized medical equipment or surgery may be necessary.

There are various types of kidney stones. Because treatment for each differs, it is important for the physician to determine the stone's mineral content and to identify any medical conditions that may have contributed to stone formation. Preventive treatment may be with medications and/or changes in the diet. About 80% of all kidney stones are composed of calcium and other minerals, usually a combination of calcium and oxalate. In some cases, dietary adjustments help to prevent the recurrence of these types of stones.

Special Considerations

1. Increase fluid intake. This is the most important preventive measure for all patients who develop kidney stones. It hinders the formation of stones by diluting the urine. Patients should drink enough fluid to produce

two quarts or more of urine each day. As a guideline, drink 8-10 oz of fluid (on average =250 ml=1 cup) every hour while awake and 8-10 oz once during the night if awakened for some reason. At least 50% of the total fluid intake should be water. In warmer climates and for physically active people, an even higher fluid intake is recommended.

2. Calcium: Calcium from food sources is absorbed during digestion in the intestines.

PREVENTIVE TREATMENT MAY BE WITH MEDICATIONS AND/OR DIET CHANGES.

The body uses this mineral for many important functions. Any excess that has been absorbed is excreted or passed through the kidneys. The biggest portion of calcium in the diet comes from milk and foods made from large amounts of milk, such as cheeses and yogurt. The calcium in these foods is usually easily absorbed. Other foods, such as dark green leafy vegetables, contain significant amounts of calcium. However, they also contain other substances which prevent the body from readily absorbing the calcium. So, the amount of available calcium in green leafy vegetables is less than in milk. Certain antacids and over-the-counter medications also contain calcium that may or may not be in a form the body can absorb. Consume your daily needs for calcium which is approximately 2 cups of milk or yogurt with 60 grams of cheese or 4 table spoons of Labna.

If the physician has recommended a calciumcontrolled diet, the idea is to keep calcium intake within a narrow range, not too much and not too little. On this diet, men are advised to limit calcium intake to 800 mg per day. Prior to menopause, women should limit calcium to 1000 mg per day; and after menopause, these women should have 1200 mg of calcium a day.

3. Oxalic acid or oxalate is found mostly in foods from plants. Calcium combines with oxalate in the intestines. This reduces calcium's ability to be absorbed. Sometimes oxalate or calcium oxalate stones form because there is not enough calcium in the intestines. Then, too much oxalate goes to the kidneys to be excreted through urine, this is called hyperoxaluria. In certain cases of oxalate or calcium oxalate stones, the physician may recommend reducing oxalate intake along with a slight increase in calcium. It is recommended that these patients have no more than 50 mg of oxalate per day in the diet. To do this, foods with high or moderate amounts of oxalate should be reduced or eliminated from the diet.

Although there are many foods that contain large amounts of oxalate, eight foods have been shown to be most at fault for raising

urine oxalate levels. They are rhubarb, spinach, strawberries, chocolate, wheat bran, nuts, beets, and tea.

4. Sugar, sodium, and animal protein: It has been found that too much of these may also aggravate the development of calcium or calcium oxalate stones. Natural sugars found in food are not a concern. However, people who get kidney stones may benefit from avoiding packaged foods with large amounts of added sugars, and from reducing sugars added in food preparation and at the table.

Reducing sodium in the diet appears to reduce the amount of calcium excreted in the urine. Consequently, people who develop stones containing calcium may benefit from keeping sodium intake between 2300 to 3500 mg a day. A diet high in animal protein affects certain minerals in the urine that may promote the formation of kidney stones. Therefore, people who tend to develop kidney stones should avoid eating more protein than the body needs each day. The physician or registered dietitian can recommend a daily protein intake for individual patients.

5. Insoluble fiber: There are two types of fiber: soluble (dissolves in water) and insoluble. Both provide important functions in the body, but it is insoluble fiber (found in wheat, rye, barley, and rice) that may help to reduce calcium in the urine. It combines with calcium in the intestines, so the calcium is excreted with the stool instead of through the kidneys. Insoluble fiber also speeds up movement of substances through the intestine, so there will be less time for calcium to be absorbed.

6. Vitamin C: Your body may turn extra vitamin C into oxalate. Avoid high doses of vitamin C supplements (more than 2,000 mg of vitamin C per day).

WHEN KIDNEY STONES ARE QUITE TINY, THEY MAY PASS UNNOTICED WITH THE URINE. OFTEN HOWEVER, THEY GROW TOO LARGE TO PASS EASILY THROUGH THE URINARY TRACT, AND SOME STONES HAVE ROUGH OR SHARP EDGES. WHEN THESE STONES ARE PASSING THROUGH THE URINARY TRACT, IT CAN BE QUITE PAINFUL. IN SOME CASES, KIDNEY STONES CANNOT PASS ON THEIR OWN, AND TREATMENT WITH SPECIALIZED MEDICAL EQUIPMENT OR SURGERY MAY BE NECESSARY.

In the realm of healthcare, the Pediatric Emergency Department stands as a sanctuary of hope and resilience, dedicated to addressing the urgent medical needs of our youngest and most vulnerable patients. Hospitals and medical centers worldwide have recognized the unique healthcare requirements of children, leading to the establishment of specialized emergency departments. These units are staffed by a multidisciplinary team of healthcare professionals, each bringing a wealth of expertise and a compassionate approach to care. This team includes pediatricians, nurses, and technicians, all specially trained to navigate the complexities of pediatric emergencies, ensuring that every child receives the personalized and meticulous care they deserve.

Despite the relative rarity of pediatric emergencies, they pose a distinct challenge to medical staff, particularly because of the patients' inability to communicate their symptoms and needs effectively. The broad spectrum of conditions, combined with the physiological, anatomical, and psychological changes that children undergo, demands a specialized approach to emergency care that is sensitive to the unique characteristics of this patient group.

Recognizing the need for specialized care, the Pediatric Emergency Department was conceived as a haven where children and their families could receive comprehensive support. Pediatric specialists play a crucial role in alleviating the natural anxieties associated with illness and medical procedures. Their expertise is complemented by a team that operates under the guidance of pediatric consultants, ensuring a holistic approach to treatment and care.

Design and Facilities Tailored for Children

The Pediatric Emergency Department distinguishes itself through its child-centric design and facilities. Emphasis is placed on creating a safe, comfortable, and engaging environment that caters to the emotional and physical needs of children and their families during critical times. The department is equipped with the latest medical devices and equipment specifically

designed for pediatric care, from artificial ventilation to diagnostic tools, ensuring that every aspect of the child's well-being is addressed.

Comprehensive Services and Specialized Care

Services in the Pediatric Emergency Department are comprehensive and meticulously tailored to meet the urgent needs of young patients. Rapid diagnosis and assessment are prioritized to determine the most effective care plan swiftly. Urgent care services are readily available, offering everything from medication administration to respiratory support and necessary medical procedures. Moreover, seamless coordination with other hospital departments ensures that children receive integrated care, whether they need surgery or intensive care.

The Hallmarks of Pediatric Emergency Departments

Human interaction and communication are paramount in pediatric emergency care. The department's staff is trained to engage with children and their families compassionately, understanding the importance of sensitivity to the needs and emotional states of young patients. The environment is designed to be welcoming and entertaining, with toys and activities available to alleviate stress and anxiety.

Family support is another critical component. Recognizing the emotional toll on families, the department provides emotional support and information to help them navigate the challenges of emergency medical situations.

Emergency Cases and the Spectrum of Care

The Pediatric Emergency Department covers a wide array of emergency conditions, from severe asthma attacks and high fevers to traumatic injuries and allergic reactions. The goal is always rapid response, accurate diagnosis, and immediate care, utilizing state-of-the-art technology to ensure the best possible outcomes.

Professionalism and Empathy: The Cornerstones of Pediatric Emergency Care

RECOGNIZING THE NEED FOR SPECIALIZED CARE, THE PEDIATRIC EMERGENCY DEPARTMENT WAS CONCEIVED AS A HAVEN WHERE CHILDREN AND THEIR FAMILIES COULD RECEIVE COMPREHENSIVE SUPPORT. PEDIATRIC SPECIALISTS PLAY A CRUCIAL ROLE IN ALLEVIATING THE NATURAL ANXIETIES ASSOCIATED WITH ILLNESS AND MEDICAL PROCEDURES.

Professionals working in this specialized department are highly skilled in emergency techniques, from clinical assessment to airway management and resuscitation. Their training goes beyond technical proficiency, emphasizing the importance of empathy, communication, and psychological support.

Understanding the child's physiology and the impact of medical emergencies on their mental state is crucial for providing comprehensive care that addresses both physical and emotional needs.

Emotional Response and the Role of Caregivers

The emotional well-being of pediatric patients is a critical focus of the emergency department. Children's responses to medical emergencies can vary widely, influenced by their

age, developmental level, and the severity of their condition. Healthcare providers are adept at navigating these emotional landscapes, providing reassurance and support to both children and their families.

A Synergy of Care in Pediatric Emergencies

The Pediatric Emergency Department epitomizes the synergy between medical expertise and compassionate care. It is a place where the emotional and physical needs of children are addressed with the utmost sensitivity and professionalism. In this unique healthcare setting, children and their families find not just medical intervention but a comprehensive support system designed to guide them through the most challenging moments, offering hope and healing on the journey towards recovery.

THE EMOTIONAL WELL-BEING OF PEDIATRIC PATIENTS IS A CRITICAL FOCUS OF THE EMERGENCY DEPARTMENT.

CHILDREN'S RESPONSES TO MEDICAL EMERGENCIES CAN VARY WIDELY, INFLUENCED BY THEIR AGE, DEVELOPMENTAL LEVEL, AND THE SEVERITY OF THEIR CONDITION.

HEALTHCARE PROVIDERS ARE ADEPT AT NAVIGATING THESE EMOTIONAL LANDSCAPES, PROVIDING REASSURANCE AND SUPPORT TO BOTH CHILDREN AND THEIR FAMILIES.

Diabetes and Oral Health

Dr. Smitha Bhagavathi Kandi, General Dentist

Diabetes is a metabolic disease which affects our whole body. There is a strong relation between diabetes and oral health. The oral changes are more common in uncontrolled diabetes.

The reasons for oral changes are due to:

1. Weakening of immune system (defense mechanism)

2. Blood vessel thickening (which reduces the blood flow to tissues)

Oral Changes in uncontrolled diabetes

1. Cheilosis - the corners of the mouth become inflamed, which can lead to cracking and pain

2. Dry mouth—Due to reduced salivary flow – which leads to tooth cavities

3. Burning sensation

4. Poor healing of oral wounds

5. Thrush- Fungal infection

6. Gum diseases:

• Bleeding on brushing

• Gum abscess

• Gum pockets

• Enlarged gum

• Gum polyps

• Gradual loss of teeth- bearing jaw bones and loosened teeth

How can we prevent oral problems in diabetes?

1. Keep blood sugar as close to the normal level as possible by following the physician’s instructions.

2. Prevent plaque buildup on teeth surface by thorough brushing and flossing. Use interdental small brush if there is a wide gap between the teeth.

3. Make regular dental check-ups and do professional teeth cleaning.

4. If you wear dentures remove and clean them daily.

5. Avoid smoking (Gum disease is 20 times more in diabetic patients with smoking habit)

THE ORAL CHANGES ARE MORE COMMON IN UNCONTROLLED DIABETES.

Making Life Easier and Smoother for Diabetic Patients

Despite the absence of a cure for diabetes, effectively managing the condition through lifestyle changes, medication adherence as prescribed by a physician, and self-care education can significantly improve a patient's quality of life, making it easier and smoother. Several daily strategies and measures can enhance the quality of life for diabetic patients, including adopting a healthy diet, engaging in regular physical activity, continuous monitoring of blood sugar levels, collaborating with a medical team, and acquiring self-care education. Additionally, support from family, friends, and healthcare professionals, along with staying informed about treatment options and expectations, can make living with diabetes more manageable.

Education and Empowerment

Proper education and empowerment help diabetic patients improve their ability to manage the disease and make informed decisions. Patients should be well-versed in basic knowledge about diabetes, how to measure blood sugar levels, and regulate medication dosages. A deep understanding of diabetes helps patients spot early warning signs, maintain their treatment plans, and significantly decrease the chance of serious health issues, thereby preventing the triggers that could lead to further diabetic complications. Educating diabetic patients improves overall health, as knowledge about the disease empowers them to lead a healthy lifestyle and equips them with the skills to handle the psychological and social challenges of diabetes. Consequently, feeling confident and in control of their condition provides patients with a greater sense of happiness and satisfaction.

Adopting a Healthy Diet

A healthy diet is crucial for diabetic patients to manage their blood sugar levels. It helps regulate blood sugar levels, prevent sudden spikes or drops, and reduce the risk of diabetes

complications, potentially decreasing the need for medications. Guidance from a specialized dietitian is essential to determine an appropriate diet plan that meets the patient's nutritional needs. Maintaining a healthy and balanced diet that includes complex carbohydrates, proteins, fibers, and healthy fats is vital.

Regular Physical Activity

Regular physical activity improves insulin sensitivity, controls blood sugar levels, and enhances overall fitness. Patients are advised to engage in moderate-intensity physical activity for at least 150 minutes per week, spread over at least three days. Regular exercise controls blood sugar levels by stimulating muscles to use blood glucose for energy and increases the body's insulin sensitivity, thereby reducing the risk of diabetes complications.

Continuous Blood Sugar Monitoring

Ongoing monitoring of blood sugar levels helps track values, adjust medication dosages, nutrition, and physical activity based on readings. Diabetic patients should regularly monitor their blood sugar levels using a glucose meter, playing a crucial role in managing diabetes effectively and adhering better to the treatment plan, thus reducing the risk of complications.

Weight Management

Maintaining a healthy weight is essential for managing diabetes. Even a small amount of weight loss can have significant health benefits, including improved blood sugar, blood pressure, and cholesterol levels. Weight management reduces insulin resistance, enhancing the body's ability to use sugar and decreasing the secretion of glucagon, which causes high blood sugar levels.

Adherence to Medication

Patients must follow the doctor's instruc-

DIABETIC PATIENTS SHOULD REGULARLY MONITOR THEIR BLOOD SUGAR LEVELS USING A GLUCOSE METER, PLAYING A CRUCIAL ROLE IN MANAGING DIABETES EFFECTIVELY AND ADHERING BETTER TO THE TREATMENT PLAN, THUS REDUCING THE RISK OF COMPLICATIONS.

tions and dosage schedule precisely. Good adherence to treatment can achieve better blood sugar level balance. Diabetic patients should carefully follow the doctor's instructions regarding medication, including the type, dosage, timing, and duration of medication intake as prescribed.

Communication with the Medical Team

Maintaining good communication with the treating medical team, including the treating doctor, experienced nurse, and dietitian, is crucial. Regular communication helps assess and address challenges related to diabetes management. Regular interaction with the medical team provides personalized care, offering precise guidance based on the patient's condition and individual needs, along with emotional support and motivation to handle diabetes challenges.

Connecting with Others

Joining diabetes support groups and talking with family and friends can improve a diabetic patient's life. It's important to be surrounded

by a strong support network to help deal with the psychological and emotional challenges. Connecting with others provides strong emotional support, offering encouragement and understanding in facing diabetes challenges and daily management.

Stress Management

Effective stress management is crucial, as psychological stress can affect blood sugar levels. Techniques like meditation, relaxation, and stress-reducing activities help achieve emotional balance. Continuous stress can impact other factors like sleep patterns, physical activity, and nutrition; managing and reducing stress contributes to better diabetes management and overall health. By embracing a comprehensive approach that includes education, dietary adjustments, regular exercise, diligent monitoring, and support, individuals with diabetes can lead fulfilling lives. Each element of this strategy plays a crucial role in smoothing the path of diabetes management, demonstrating that with the right knowledge and support, living well with diabetes is entirely achievable.

JOINING DIABETES SUPPORT GROUPS AND TALKING WITH FAMILY AND FRIENDS CAN IMPROVE A DIABETIC PATIENT'S LIFE. IT'S IMPORTANT TO BE SURROUNDED BY A STRONG SUPPORT NETWORK TO HELP DEAL WITH THE PSYCHOLOGICAL AND EMOTIONAL CHALLENGES.

26-28 May 2024

Al-Ahli Hospital diagnoses digestive diseases using the smart capsule

Dr. Wissam Malki, Gastroenterologist Consultant at Al-Ahli Hospital/Qatar

The capsule is characterized by reaching the most accurate places in the body and photographing it with high quality.

In order to accurately diagnose gastrointestinal diseases, Al-Ahli Hospital has recently developed a device in the form of a smart capsule. It is very small in size with a special wireless diagnostic camera, placed inside a capsule that the patient swallows, and while it is passing in the digestive system, it

takes thousands of pictures of the stomach, intestines and other parts. Images are recorded and sent to a receiver installed around the patient's waist. The capsule remains in the patient's body for a period of 8 to 12 hours approximately and is passed out with the stool, and is not reused after that. The capsule has several advantages, including its ability to access to places that cannot be reached by the normal endoscopy device in addition to the accuracy and clarity of its images and the

AL-AHLI HOSPITAL HAS RECENTLY DEVELOPED A DEVICE IN THE FORM OF A SMART CAPSULE

magnification that it provides. By using the capsule, the patient does not need to stay in the hospital or undergo anesthesia.

Dr. Wissam Malki, Gastroenterologist Consultant at Al-Ahli Hospital said that, “It is possible to conduct an endoscopy using the smart capsule in the following cases: anemia, acute or chronic bleeding cases without a clear cause, small intestine inflammation, colon diseases, tumors, small intestine diseases and vascular dysplasia. In addition, this technology is useful in diagnosing patients who are unable to tolerate the normal laparoscopic operation and diagnosing other cases that are determined by the physician”. He also noted that, "This type of diagnosis can be used for the elderly who are unable to tolerate anesthesia and endoscopy by using normal devices. It is also useful for diagnosing pregnant women and persons who do not want to undergo anesthesia."

Dr. Malki indicated that the capsule camera

or endoscope is equipped with a camera with two high-resolution lenses swallowed by the patient with a sip of water and takes its entire journey from the mouth opening until it reaches the anus and comes out with the stool, and it takes accurate imaging at a rate of 3 images per second, equivalent to 180 images per minute, and then sends these images to a small receiver attached to the patient's trouser belt.

Dr. Malki stated that in the past, transferring images from inside the patient’s intestine was very difficult, but through this new technology, it has become easier for doctors to perform an operation inside the patient’s intestine through a micro-capsule carrying two small camera lenses that the patient swallows.

IT IS POSSIBLE TO CONDUCT AN ENDOSCOPY USING THE SMART CAPSULE IN THE FOLLOWING CASES: ANEMIA, ACUTE OR CHRONIC BLEEDING CASES WITHOUT A CLEAR CAUSE, SMALL INTESTINE INFLAMMATION, COLON DISEASES, TUMORS, SMALL INTESTINE DISEASES AND VASCULAR DYSPLASIA.

M42 launches new clinic for preventive menopause solutions and treatment

In celebration of International Women’s Day on March 8, health-tech powerhouse M42 is launching the 'Laha Wellness Hub,' a dedicated preventive women’s wellness clinic at HealthPlus Family Clinic in Al Bandar, Abu Dhabi. This specialized clinic, tailored for women aged 35 and above, aims to empower women through a holistic approach to wellness, focusing on preventive care, personalized plans and educational support that address issues such as menopause and fertility. M42 has also made the clinic available to its staff as part of a new corporate policy to support female staff through menopause and promote gender equity.

As well as impacting quality of life and the ability of women to carry out routine tasks in their daily lives, the menopausal transition can affect performance at work and, consequently, opportunities for career development and progression. According to the Faculty of Occupational Medicine (FOM) in the UK, almost 80 percent of menopausal women are in work. 75 percent of women experience symptoms, and 25 percent experience serious symptoms. Women experiencing menopause can encounter multiple and often overlapping and debilitating symptoms including headaches, fatigue and mental health impacts such as low mood and reduced self-esteem. The Laha Wellness Hub operates on the premise that no two women are the same and neither is their journey through life and womanhood. The clinic provides a gateway to comprehensive services across the M42 network, that can address the full range of women’s health needs including perimenopause, menopause management, endometriosis, premature ovarian failure, cardiovascular care, fertility, and more.

The clinic is staffed by a supportive team of dedicated female healthcare professionals, including specialists in women's health, family medicine, gynecology, physiotherapy, and other holistic solutions. The clinic will help women track and monitor conditions that may help reduce the severity of the symptoms women of-

ten face during this time of their lives including preventive solutions for fertility issues that are more common for women over 35.

Hasan Jasem Al Nowais, Managing Director and Group Chief Executive Officer, M42 said: "I am proud to announce M42’s dedicated women’s wellness clinic that goes beyond traditional healthcare. The 'Laha Wellness Hub’ is a groundbreaking initiative that will pioneer preventive care, educate and support for women over the age of 35 on their unique wellness journey. M42 aims to create a community and support network for women, rewriting the narrative around largely unspoken women’s health topics such as perimenopause and menopause, empowering women to navigate this journey with confidence. This is a holistic commitment to the wellbeing of our community, reflecting our dedication to a healthier, more equitable future.”

The Laha Wellness Hub offers distinctive features, including a preventive approach, holistic wellness, personalized care plans, and access to state-of-the-art facilities across the M42 network including Danat Al Emarat Wom-

M42, COMMITTED TO SUPPORTING WOMEN’S HEALTH, LAUNCHES NEW CORPORATE POLICIES TO PROMOTE GENDER EQUITY AND SETS THE BENCHMARK FOR BEST PRACTICES GLOBALLY

en & Children’s Hospital and the HealthPlus Fertility Center, also extending access to Dubai and northern Emirates residents via Mubadala Health Dubai. M42 has made booking an appointment at the Laha Wellness Hub easy and convenient through the M42 app.

To further support the wellbeing of its employees and encourage a preventive approach to health, M42 has introduced a half-day wellbeing leave policy for all its staff. Allowing them to prioritize their health through easy access to preventive services such as the Laha Wellness Hub.

Suaad Al Hammadi, Group Chief Human Capital Officer at M42, said: “We are committed to prioritizing the health and wellbeing of our employees, they are after all, our greatest asset. We understand that menopause can have a dramatic impact on life as a whole for women, and this includes work, how they feel at work, their productivity and the choices they make when it comes to their career. It is a condition that is not often acknowledged or addressed, yet it impacts such an enormous number of women globally".“More than 60% of our workforce is made up of women, so ensuring we are empowering them throughout every stage of their career is important to us. Our new policy aims to give our staff access to preventive solutions, such as the Laha Wellness Hub offers, so they can take control of their health,” Suaad added.

Dr. Neha Gami, Consultant, Obstetrics & Gynecology, from HealthPlus Family Center, Al Bandar, Abu Dhabi emphasized the importance of the clinic in addressing the underserved needs of women, saying: "Women make up 50 percent of the global population, but tend to neglect their own health needs, especially when it comes to menopause. Empowering women starts with addressing their unique needs. The 'Laha Wellness Hub' champions women's health and fills a crucial gap, offering specialized preventive care and education, ensuring every woman's wellbeing is a priority."

Donna Howarth, Founder of Middle East Menopause Organisation (MEMO) wholeheartedly welcomes the opening of the clinic and views it as a significant step forward in changing the menopause landscape in the UAE. “Choice is of significant importance - offering a variety of approaches and options enables women to make informed decisions. Moreover, the clinic signifies a broader recognition of menopause which helps to destigmatize and encourage open conversation”.

As part of the initiative, M42 will roll out an education campaign across its network on International Women’s Day, emphasizing the importance of preventive care and women's health. This aligns with M42's commitment to being a champion for women’s health in the region and globally, supporting health equity through partnerships with female empowerment organizations, such as Aurora50.

THE 'LAHA WELLNESS HUB' CHAMPIONS WOMEN'S PREVENTIVE HEALTH, PROVIDING IMPROVED ACCESS AND SUPPORT FOR THE UNIQUE HEALTH CONCERNS OF WOMEN AGED 35 AND ABOVE, INCLUDING MENOPAUSE AND FERTILITY.

The 9th edition of the GCC Regulatory Affairs Pharma Summit

is set to convene in Dubai in 2024, marking a significant gathering of over 400 professionals, including regional governmental officials and industry experts

Themed "Navigate Pharma Regulations with ease & Amplify Commercial Success" this 5 days’ summit will take place at the Mövenpick Grand Al Bustan - Dubai, UAE on April 22-26, 2024, which includes the following events and trainings:

• Date: April 22-23 | GCC Regulatory Affairs Pharma Summit

• Date: April 24-25 | GCC Pharmacovigilance Training

• Date: April 24-25 | GCC Medical Tender & Business Talk

• Date: April 26 | GCC Quality Conference

• Date: April 26 | eCTD Training

"At the summit, face-to-face between governmental entities and industry professionals will be the scope focus with a wealth of exchange in regulatory insights," emphasizes Dr. Najiba Al Shezawy, Founding Member, and Managing Director of PRA Consultancy. "I urge industry stakeholders to capitalize on this opportunity for collaboration and advancement, fostering growth and innovation in our field."

This summit serves as a pioneering platform in the region, uniting government representatives, industry leaders, and solution providers to delve into the latest regulations shaping the pharmaceutical landscape. The agenda will feature immersive workshops and roundtable discussions centered on key topics such as Regulatory Digital Transformation and Data Safety, Pharma Manufacturing in the GCC, Track and Trace, Reliance, and the Regional Regulatory Updates in the GCC Region.

"Effortlessly navigating pharmaceutical regulations and maximizing commercial success is paramount for the embitterment of the industry, specifically since the pharmaceutical industry is on a continuous-commercial growth." asserts Dr. Mona Al Moussli, Co-Founder &

THIS SUMMIT SERVES AS A PIONEERING PLATFORM IN THE REGION, UNITING GOVERNMENT REPRESENTATIVES, INDUSTRY LEADERS, AND SOLUTION PROVIDERS TO DELVE INTO THE LATEST REGULATIONS SHAPING THE PHARMACEUTICAL LANDSCAPE.

Managing Director of PRA Consultancy. She adds: "By staying informed and embracing networking opportunities, professionals can excel in this dynamic industry landscape. The summit facilitates this by providing invaluable insights into regulatory compliance and strategies for enhancing commercial outcomes."

With a robust lineup of sponsors and exhibitors, including industry leading companies like Extedo, ACG Inspection, Sanofi, Honeywell, PI Pharma Intelligence, Hikma Pharmaceuticals, Ipsen, Julphar, Schlafender Hase, Inc., RAS LSS, Bayer, Takeda, Tabuk, RegOrbit, State of Practices Consultancy Center (SOP), AbbVie, Evoteq, Cosmotrace, VISIOTT Traceable Packaging Solutions, Thriive.ai, and many more sponsors that are yet to be announced, are joining this summit that promises enriching discussions and future industry trends. Anticipated to draw over 400 experts and representatives from governmental organizations and the pharmaceutical regulatory sector, the summit offers a platform for engaging debates, knowledge exchange, and networking opportunities.

For further details on the 9th edition of the GCC Regulatory Affairs Pharma Summit, visit: www.pramagcc.com

Emerging alternative therapy for non-muscle-invasive bladder cancer (NMIBC) in the era of BCG shortage and BCG failure

Dr. Michael A. O’Donnell and Mohamad Abou Chakra

Bladder cancer epidemiology and treatment of NMIBC

Bladder cancer is the 10th most common cancer worldwide, with more than 600,000 new cases diagnosed each year. It is considered the 4th most common cancer in Arab countries. Seventy percent of cases are identified at an earlier stage (non-muscle-invasive (NMIBC)), where treatment after endoscopic removal, relies on the administration of drugs into the bladder (intravesical therapy). Bacillus CalmetteGuerin (BCG), a vaccine originally developed to prevent tuberculosis, has become the highly effective standard-of-care to both prevent NMIBC recurrence and eradicate the ofteninvisible, high-grade and deadly surface cancer called carcinoma-in-situ (CIS). Unfortunately, BCG fails in 40% of cases by 2 years. Furthermore, worldwide shortages of BCG that started in 2012, continue to be commonplace, this congruence of BCG shortage and failure has become a health catastrophe in search of new topical NMIBC treatments.

Impact of BCG shortage and BCG failure among Arab urologists

A survey was constructed and sent through the Arab Association of Urology (AAU President: Mohamad Moussa - Lebanon), to assess BCG shortage and BCG alternatives. More than 60% of Arab urologists reported shortages of BCG. Coping strategies included: dose reduction of BCG, prioritizing BCG for certain tumor stages (T1 or CIS), and using second-line alternatives such as chemotherapy. The most favored management strategy for BCG-unresponsive NMIBC was radical cystectomy, but still about half felt other conservative treatments were warranted utilizing a variety of intravesical chemotherapy agents but with single agent gemcitabine preferred, a drug with poor activity (< 20% by 2 years) against BCG-unresponsive CIS.

Intravesical Gem/Doce, a potential solution to these BCG-related problems

A BCG-alternative and BCG-rescue therapy for direct bladder instillation was developed by Dr. Michael O’Donnell, Professor and Director of Urologic Oncology, at the University of Iowa (UI) in the US in 2015. It consists of the sequential use (one right after the other) of two common and cheap generic chemotherapy drugs, gemcitabine and docetaxel (Gem/Doce). Therapy

THE MOST FAVORED MANAGEMENT STRATEGY FOR BCG-UNRESPONSIVE NMIBC WAS RADICAL CYSTECTOMY.

US. Professor Michael A. O’Donnell (left) and Mohamad Abou Chakra (right).

consists of weekly bladder treatment X 6 then once monthly treatment for up to 2 years. Each drug is held in the bladder for 60-90 minutes before drainage or voiding.

In terms of efficacy, ~75% of BCG naïve cases (never given BCG) and 42% of BCG failure cases (previously treated with BCG and failed on this therapy) remain free of any cancer recurrence 2 years later if they had received Gem/Doce. Additionally, this therapy was found to work at least as well as BCG for both high and intermediate-risk BCG-naïve cases and even for CIS regardless of its location, including in the upper urinary tract. For BCG-unresponsive CIS cases, Gem/Doce easily outperformed, by more than 2-fold, the effectiveness reported by any single chemotherapy drug (like gemcitabine) and the three FDA-approved agents (Valrubicin (Valstar), pembrolizumab (Keytruda) and nadoferagene firadenovec (Adstiladrin)). However, it should be noted that the evidence supporting Gem/Doce effectiveness is, to date, only derived from retrospective studies (albeit from several multi-institutional series) rather than randomized trials.

Side effects of Gem/Doce therapy

More than 400 patients have received intravesical Gem/Doce at UI Hospitals & Clinics over almost a ten-year period. Over half of the patients treated had no side effects what-soever and less than 1% had a grade 3 treatmentrelated adverse event. Most of the adverse events after Gem/Doce therapy have been grade 1-2 and mostly mild fatigue or irritative urinary symptoms (dysuria, frequency, and hematuria). In fact, the dropout rate for patients getting Gem/Doce was 3-fold lower (3%) than what was observed for the contemporarily BCG-treated patients (~9%). Furthermore, an independent randomized study from India comparing Gem/ Doce to BCG demonstrated not only statistically significantly less grade 2 side effects but also better quality of life scores for patients receiving Gem/Doce.

Why has Gem/Doce not become routine therapy among Arab urologists?

While in our survey 30% of Arab urologists used intravesical chemotherapy as an alternative

treatment for patients in whom BCG failed, only 10% of these urologists reported using Gem/ Doce. The reason for low Gem/Doce use is likely several fold. Gem/Doce has not been widely promoted by any pharma company so adoption has been slow. While 70% of US urologic bladder cancer specialists reported using Gem/Doce recently, among US community urologists, a similar survey revealed Gem/Doce use was also under 10%. Treatment logistics have also likely played a role. Since patients must wait at their urologist’s office for 1-2 hours to receive sequenced Gem/Doce (vs 10-15 minutes for BCG), workflow can be challenging for a busy clinic with limited waiting space. Most Arab (and US community) urologists are also personally unfamiliar with new intravesical drugs like docetaxel, let alone any doublet intravesical chemotherapy. Furthermore, while the NCCN now in 2024 mentions Gem/Doce as treatment option for BCG-unresponsive NMIBC, European and most local guidelines do not.

However, this situation is poised to change. As per professor Moussa, President of the AAU,

“This novel Gem/Doce therapy, may constitute an alternative to the classic treatment of bladder cancer, especially in underdeveloped countries, decrease the cost burden on the healthcare system, and allow us to treat more patients.”

Future perspectives

A randomized Phase III trial is ongoing to assess the use of intravesical BCG versus Intravesical Gem/Doce in treatment for BCGnaive non-muscle invasive bladder cancer (the BRIDGE Trial). This will provide level 1 evidence of this novel therapy. Further prospective trials of Gem/Doce among patients in whom BCG has failed, are also in development, including in Arab nations.

Message to bladder cancer patients

Despite the fact that bladder cancer is a difficult disease to treat, there are multiple novel therapies emerging to help patients in their battle with this cancer. Gem/Doce offers a novel strategy using commonplace generic chemotherapy drugs that are both safe and effective, and potentially available to all parts of the Arab world, regardless of economic status.

Dr. Michael O'Donnell, BA, MD, is the Richard D. Williams Professor and Director of Urologic Oncology at the University of Iowa Carver College of Medicine and a member of the Holden Comprehensive Cancer Center. The development and enhancement of bladder immunotherapy have been his research focus for more than 20 years. He has also pioneered the use of combination intravesical chemotherapy in early bladder cancer. He has authored over 250 peer-reviewed manuscripts, 10 book chapters, and multiple reviews and abstracts. Dr. O’Donnell also serves on the editorial board of the Journal of Urology and CURE.

Dr. Mohamad Abou Chakra, MD, is a graduated urologist from the Lebanese University and Sorbonne University. He is currently a clinical research fellow in urologic oncology at the University of Iowa. His clinical and research focus is on understanding and treating patients with urothelial carcinoma. He serves on the editorial board of several high-impact journals and has written more than 75 peer-reviewed articles, mostly in urologic oncology.

Glance To the Future Landscape of Mental Health and Substance Abuse Care

Dr. Ali Elhaj, CEO, Ardens Health Chair, Governance, Leadership and Research Division Arab Hospital Federation

The future of mental health and substance abuse care is being shaped by several key factors that are revolutionizing the healthcare system.

One of the most significant shifts is the integration of mental health services into primary healthcare systems. This change acknowledges the importance of mental health in overall well-being and allows for earlier access to screenings, interventions, and support. By embedding mental healthcare within the primary healthcare framework, stigma is reduced, early detection and treatment are facilitated, and coordinated care becomes the norm.

Advancements in digital health technologies such as teletherapy platforms and mobile apps are facilitating remote support and self-management tools that make mental healthcare more accessible and continuous.

Additionally, the application of Artificial Intelligence to process genetic information and individual health data is reshaping how substance abuse and mental disorders are treated. This approach tailors treatments to the specific needs and characteristics of each patient, resulting in improved outcomes and a reduced likelihood of relapse. Understanding

the complex interplay between genetics, environment, and personal history in these conditions, this advancement fosters more effective interventions and encourages greater patient involvement in their treatment.

In the realm of governance, governments and private sectors are re-evaluating legislative frameworks to ensure equal treatment for mental and physical health conditions. Policies, regulations, and insurance coverage are broadening their scope through increasing funding for public mental health initiatives, and facilitating remote care through telehealth. These changes aim to create a more inclusive healthcare system recognizing quality mental health and substance abuse treatments as fundamental rights.

“An ounce of prevention is worth a pound of cure”. Community-based awareness campaigns, school programs, and accessible screening services play a crucial role in educating the public, promoting strategies for resilience and coping, and early detection. By focusing on prevention and early intervention, healthcare providers can address health issues before they escalate into more severe conditions, thus reducing the overall burden on the healthcare system. This proactive approach not only promotes better health outcomes but also ensures the efficient allocation of resources, which is crucial for the long-term sustainability of healthcare services.

For all these shifts to be effective, addressing the stigma surrounding mental health and substance abuse is essential for its integration into the broader healthcare system. Public education efforts can reshape perceptions, debunk myths, and highlight the effectiveness of treatment. By promoting understanding and empathy, public awareness initiatives reduce barriers to care and encourage individuals to seek assistance without fear of judgment.

Looking towards the future, the integration of holistic approaches in mental health and substance abuse care promises a transformative shift. Comprehensive wellness includes physical, emotional, and social well-being, leading to more proactive, personalized and effective treatments and care. This evolution represents a fundamental change to the traditional definition of health and wellness, approaching the person as an entirety of interconnected mind, body, and spirit.

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