This report reviews the Global Environment Facility’s (GEF’s) collaboration with developing nations and countries with transitional economies in five regions to conserve internationally significant species of plants and animals. GEF projects encourage sustainable uses of biological diversity, including uses by people dependent on natural resources for their livelihood. The report describes GEF projects by region in a range of ecosystems, including drylands, forests, and mountains as well as freshwater, marine, and coastal areas. Readers will gain an understanding of how GEF and its implementing agencies work with countries to ensure that the project development process is driven by countries and reflects their national development priorities.