THE
LITTLE HAWK Iowa City, IA
Vol 74
Friday, September 30th 2016
Issue 1
thelittlehawk.com
‘66 Alumni Thomas Cech a Leader in Cancer Research
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By Victor Kalil
rom a young age, Thomas Cech had a deep passion for geology, investigating rocks, and minerals. As he went through high school, he still pursued this interest, frequently chatting with geology professors at the University of Iowa. Despite his childhood interest in science, Cech developed interests in varying subjects in college, discovering a passion for literature much like his passion for physical chemistry. As he began research he quickly found out that traditional chemistry was not the subject he wanted to explore for the rest of his life. Cech was searching for a different lab to work in and he eventually met John Hearst, a chemistry professor at the University of California, Berkeley, studying chromosomes. “[John Hearst] was sort of bouncing off the walls with excitement about chromosomes,” Cech said. “And I didn’t know much about chromosomes but I thought, ‘Wow! This is really interesting!’” Cech continued researching chromosomes and later set off to the University of Colorado Boulder, where he began his Nobel Prize winning research on RNA and its functions as an enzyme. Today, Cech continues his research, investigating certain part of the structures of our DNA and RNA. Now, Cech and his lab at he University of Colorado at Boulder are researching telomeres. Telomeres are located on the ends of chromosomes, and carry important hereditary information. Over time, the telomeres get shorter and shorter, ultimately leading to mutations. These changes in chromosome size have been linked to several age-related diseases, such as Duchenne muscular dystrophy. Additionally, tumors can grow due to the reactivation of telomerase, an enzyme that can add nucleotides and eventually lead to urothelial cancer - a common cancer that affects the urinary system. “Tumors have to stumble on some way to reactivate this process [of cell division] so they grow continuously. Those cells that don’t find some mechanism to reactivate telomerase aren’t able to continue growing,” explains Cech. “That process is one that we would like to in-
hibit, and it would be broadly applicable to all human beings.” Kevin Koepnick, City High Biology and AP Biology teacher, is very interested in this area of Cech’s research, and acknowledges its importance. “We may have approached what we can do therapeutically to make quality of life last longer,” Koepnick said. “We’ve improved nutrition, we’ve improved vaccination. We’ve eliminated infectious disease to a large extent. Now we’re working on people’s heart healthiness [and] gotten rid of poisons in the air. We’re doing pretty good there - what’s the next step? Well, [Cech’s research] is the next step.” Ever since he started working with rocks in elementary school, Cech’s drive of curiosity has not changed. He strives to always be inquisitive, and Koepnick agrees. “Just because we understand something to be true and correct, it doesn’t
ABOVE: Thomas Cech '66 answers students' questions in Opstad Auditorium on September 1st, 2016. LEFT: City, West, and Regina students gather to hear Dr. Cech speak. PHOTOS BY MOLLY LIU
mean that it is,” Koepnick said. “It means that in science, it’s our best understanding.” Cech believes that the reason for his unquenchable thirst for new discover-
ies is his engrossment in this area of research. “I think [genetic engineering] is exciting, and I think it continues to be exciting,” said Cech.
New Boundaries Emphasize Diversity By Madeline Deninger and Bella Pittman
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he appearance of the Iowa City School District is rapidly changing. With the addition of a new high school, set to open in 2017, there comes the question of who will attend the $75 million dollar school. The debate regarding school boundaries can be brought down to geography and socioeconomic diversity in schools. ABOVE: The current elementary to high school “The geography divides us up, and that’s why everyone looks at West High as the ‘rich’ sequence for Alexander and Kirkwood Elementary. INFOGRAPHIC BY MADELINE DENINGER school and city as the ‘ghetto’ school. Most people who don’t have as much money get Socioeconomic diversity in the case of the viewed badly as poor,” Amelia Gordon ‘17 school district is defined by the levels of stusaid. “I think they need to make more locadents in the free and reduced lunch program. tions out by West High for people who don’t In order to get students from low-income have as much.” neighborhoods to schools throughout the
district, promoting such diversity, busing accommodations will have to be made. “Everyone performs better when there’s diversity regarding socioeconomic status. These students will be going to universities and jobs in a couple years where they’re going to be working with people of all kinds of diversities. To not teach them life skills as far as working with people from all backgrounds would really be doing our kids a disservice,” English teacher Robin Fields said. Two of the elementary schools at the center of the socioeconomic diversity debate are Alexander and Kirkwood as they have among the highest levels of FRL students in the district. In May 2015, the Iowa City Community School Board decided on district map 5F. 5F had students from Kirkwood being fed into North Central Junior High and Liberty High
School, while Alexander would go to Northwest Junior High and West High. Supporters of these boundaries said they aimed to try to even out the levels of FRL students among the three high schools. “I’m in favor of the boundaries the school board passed in 2015 because what that did was recognize the importance of diversity, diversity not only based on race but also socioeconomically,” Fields said. Board members opposed to the bill cited crowding at North Central as a concern as well as issues with transportation. This controversy led to the boundaries being back up for debate again in May 2016. A new proposal put on the table had Kirkwood students going to Northwest Junior High and West High. Continued on A6