TRUSTED JOURNALISM AT YOUR FINGERTIPS
MAY 4, 2020 VOL. 56, No. 18
westfaironline.com
Seeking a cure
REGENERON AND NYMC IN COVID-19 STUDY BY PETER KATZ pkatz@westfairinc.com
W
hen a complex process that normally takes seven to nine months is accomplished in only eight days, you can be reasonably certain that something quite special has just happened. That certain something is establishing the clinical trial of a drug that might help treat people critically ill with COVID19. At present there are no vaccines for the novel coronavirus. The U.S. Food and Drug Administration along with experts in medicine, pharmaceuticals, education, finance, data collection and more joined to slash through red tape and arrange the rapid launch of a clinical trial organized by a team at Touro College and University System and New York Medical College (NYMC) in Valhalla and Regeneron Pharmaceuticals along with the French multinational pharmaceutical company Sanofi. Tarrytown-based Regeneron and Paris-based Sanofi had jointly developed under a global collaboration agreement the drug sarilumab, a monoclonal antibody known under the trademark Kevzara. Given by injection, the drug is approved for use to treat adult patients with moderately to severely active rheumatoid arthritis. Kevzara binds to a protein associated with the human immune system called the Interleukin 6 receptor, or IL-6, which falls into the cytokine category. By inhibiting the ability of IL-6 to stimulate an immune system response, theTWB drug Loan Decision inhibits inflammation. Banner Ad The clinical trial is to test the drug as a possible COVID-19 6” w x 1.5” h treatment. In the trial, “severe” patients require supplemental 3-24-20 oxygen without mechanical help or high-flow oxygenation. “Critical” patients need to be on high-flow oxygen or a mechanical ventilator. » CURE
The spread has taken us aback a little bit. If the person is a little bit immune compromised or a little bit obese or not able to mount a proper inflammatory reaction, in this case it is going to be devastating. — Dr. Salomon Amar
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Image created by Ellie and Anna Pagan. See page 6.
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