International Journal of Mechanical and Production Engineering Research and Development (IJMPERD) ISSN(P): 2249–6890; ISSN(E): 2249–8001 Vol. 10, Issue 3, Jun 2020, 1851–1856 © TJPRC Pvt. Ltd.
ENTEROSORBENT EFFICIENCYMINERAL ATTENUATION DURING PIG MYCOTOXICOSIS LILIA E. MATROSOVA, NAILYA N. MISHINA, SVETLANA A. TANASEVA, EVGENYA YU. TARASOVA, OLGA K. ERMOLAEVA, RAMZIYA M. POTEKHINA, EDUARD I. SEMENOV Research Scholar, Federal Center for Toxicological, Radiation and Biological Safety, Kazan, Scientific City, Russia ABSTRACT The results of the study on the use of enterosorbents (modified shungite and zeolite with a particle size of 1-6 microns) during pig mycotoxicosis are presented. Experiments were conducted on 3 groups of pigs, 25 kg (n=4) each. The first group of animals served as a biological control and during 60 days was given a "basic diet"; the second group of animals was given a "toxic diet"; the third group - a "toxic diet" and a mixture of zeolite and shungite in a dose of 0.25% of the weight of the diet. The "basic diet" was a complete mixed feed for mycotoxin-free piglets of 2-4 months of age. The "toxic diet" was a "basic diet" contaminated with T-2 toxin in a dose of 0.2 mg, zearalenone - 1 mg, indicate the expediency of zeolite and shungite use during pig mycotoxicosis. KEYWORDS: Mycotoxicosis, Pigs, T-2 Toxin, Zearalenone, Deoxynivalenol, Schungite, Zeolite, Prevention
Received: Jun 01, 2020; Accepted: Jun 20, 2020; Published: Jul 02, 2020; Paper Id.: IJMPERDJUN2020170
INTRODUCTION
Original Article
deoxynivalenol - 0.5 mg per kg of feed. The obtained results of the study of blood hemato-biochemical parameters
Mycotoxins are toxic secondary metabolites of fungi, usually found in grains, which can have serious effects on animal productivity and health. When feeding the fodder affected by mold fungi, cases of acute poisoning are recorded quite rarely, but cases of decreased productivity of the stock and deterioration of other zootechnical indicators are frequently encountered. Of the farm animals, pigs are most sensitive to mycotoxins. (Pestka, 2007; Wu, 2007; Minervini and Dell’Aquila, 2008; Chayto et al., 2011). The greatest danger to pig production is posed by trichothecene mycotoxins such as T-2 toxin, zearalenone, and deoxynivalenol. T-2 toxin is the most toxic of mycotoxins produced by fungi of the genus Fusarium (Sun et al., 2020). As early as 1973, the World Health Organization included the T-2 toxin among the inevitable contaminants in food, animal feed and agricultural products (Lin et al., 2019). The consumption of T-2 toxin causes vomiting, refusal of food, growth retardation, neuroendocrine disorders, reproductive dysfunction, immunosuppression (Kuchenbuch et al., 2019). Zearalenone is a mycotoxin that promotes estrogenic syndrome manifested by infertility, abortions, and fetal resorption (Minervini and Dell' Aquila, 2008). Exposure to ZEN on sows during pregnancy and lactation reduces the number of healthy follicles in piglets in the F1 gene, which can lead to premature oocyte depletion as an adult (Schoevers et al., 2012). ZEN and its metabolites also have a negative impact on immune function (Marin et al., 2011). Deoxynivalenol disrupts the immune response (Pinton et al., 2008) and intestinal function, causing www.tjprc.org
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