COVID-19 VACCINE TABLE 1: EUA APPROVED COVID 19 VACCINE MATRIX - ADMINISTRATION & COMPLIANCE GUIDELINES* Manufacturer / Vaccine Name
Single Dose or Series
Pfizer/BioNTech (Comirnaty®)
2 dose series
Primary Series Verification Allowances (Trojan Check Logic) • 2 matching Pfizer •
mRNA
Moderna (Spikevax)
2 dose series
mRNA
Johnson & Johnson/Janssen
Single dose
1 dose Pfizer and 1 nonmatching dose of any other vaccine approved by the WHO(not Moderna)
•
2 matching Moderna
•
1 dose Moderna and 1 nonmatching dose of Pfizer
•
One dose J&J
Time Frame 2nd dose to be received 3 weeks after 1st; 21-42 days apart
Viral Vector
2 dose series
•
2 matching AZ
•
1 dose AZ and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna)
•
Required 5 months after 2nd dose of primary series
•
Pfizer, Moderna preferred; J&J permitted 2nd dose permitted for age 50 and above 4 months after 1st booster Required 5 months after 2nd dose of primary series
• 2nd dose to be received 4 weeks after 1st
Booster allowed at least 2 mo. after last dose
Viral Vector
AstraZeneca* (Vaxzevria)
Booster
2nd dose to be given 4 – 12 weeks after 1st dose
• •
Pfizer, Moderna preferred; J&J permitted
•
2nd dose permitted for age 50 and above 4 months after 1st booster
•
Required 2 months after 1st dose of primary series
•
Pfizer, Moderna preferred; J&J permitted
•
2nd dose permitted for age 50 and above 4 months after 1st booster
•
2nd dose permitted for age 18 and above 4 months after 1st booster if 1st booster was J and J Required 5 months after 2nd dose of primary series
• • •
Pfizer or Moderna or other WHO approved booster Required 2nd dose permitted for age 50 and above 4 months after 1st booster
Notes
•
Pfizer-BioNTech or Moderna COVID-19 vaccines are preferred over the J&J/Janssen COVID-19 vaccine for primary and booster vaccination due to the risk of serious adverse events. May be considered in some situations
•
If patient has received nonapproved booster, wait 28 days before administering Pfizer booster If Pfizer booster received < 5 months after 2nd dose of primary series consider fully boosted and do not revaccinate
•
Covishield™*
2 dose series
Viral Vector
Sinopharm/BIBP*
2 dose series
Inactivated Virus
•
2 matching Covishield
•
1 dose Covishield and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna)
•
2 Sinopharm-BIBP
•
1 dose sinopharm and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna)
2nd dose to be received 6 – 8 weeks after 1st dose
2nd dose to be received 3 – 4 weeks after 1st dose 21- 28 days apart
•
Required 5 months after 2nd dose of primary series
•
Pfizer or Moderna or other WHO approved booster Required
•
2nd dose permitted for age 50 and above 4 months after 1st booster
•
Required 5 months after 2nd dose of primary series
•
Pfizer or Moderna or other WHO approved booster Required 2nd dose permitted for age 50 and above 4 months after 1st booster
•
Sinovac* (CoronaVac)
2 dose series
Inactivated Virus
Covaxin®*
2 dose series
Inactivated Virus
Covovax™*
2 dose series
•
2 matching SinovacCoronaVac
•
1 dose sinovac and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna)
•
2 matching Covaxin
•
1 dose Covaxin and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna)
•
2 matching Covovax
2nd dose to be received 2 – 4 weeks after 1st dose; 14 - 28 days
2nd dose to be received 4 weeks after 1st dose; 28 days
2nd dose to be received 3-4
•
Required 5 months after 2nd dose of primary series
•
Pfizer or Moderna or other WHO approved booster Required
•
2nd dose permitted for age 50 and above 4 months after 1st booster
•
Required 5 months after 2nd dose of primary series
•
Pfizer or Moderna or other WHO approved booster Required
•
2nd dose permitted for age 50 and above 4 months after 1st booster
•
2nd dose permitted for age 50 and above 4 months after 1st booster
•
Required 5 months after 2nd dose of primary series
•
•
•
•
•
•
•
•
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If patient has received nonapproved booster, wait 28 days before administering Pfizer booster If Pfizer booster received < 5 months after 2nd dose of primary series consider fully boosted and do not revaccinate
If patient has received nonapproved booster, wait 28 days before administering Pfizer booster If Pfizer booster received < 5 months after 2nd dose of primary series consider fully boosted and do not revaccinate If patient has received nonapproved booster, wait 28 days before administering Pfizer booster If Pfizer booster received < 5 months after 2nd dose of primary series consider fully boosted and do not revaccinate
If patient has received nonapproved booster, wait 28 days before administering Pfizer booster If Pfizer booster received < 5 months after 2nd dose of primary series consider fully boosted and do not revaccinate
If patient has received nonapproved booster, wait 28
• Protein Subunit
Nuvaxovid™* (Novavax)
2 dose series
•
2 matching Novavax
•
1 dose Novavax and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna) 1 dose Convidecia
Protein Subunit
CanSino-Convidecia
1 dose series
1 dose Covovax and one dose of Pfizer or any other vaccine approved by the WHO(not Moderna)
•
weeks after 1st dose; 21-28 days
•
Pfizer or Moderna or other WHO approved booster Required
•
2nd dose permitted for age 50 and above 4 months after 1st booster
2nd dose to be received 38weeks after 1st dose; 21-42 days
•
Booster not currently recommended. Not approved for use as a booster.
N/A
•
•
• Viral Vector Non-WHO Approved Vaccines: Sinopharm WIBP, CoviVac, EpiVacCorona, Sputnik V
•
Restart primary series with approved vaccine Pfizer/Moderna/J&J
28 days after last dose of nonapproved series
•
Required 5 months after 1st dose of primary series Pfizer or Moderna or other WHO approved booster Required Required after restarting primary series with approved vaccine (follow guidelines for series above)
*guidelines are for individuals NOT at increased risk due to moderate or severe immunocompromised The following FDA-approved (emergency use authorization, EUA and FDA approved) vaccines are accepted for meeting COVID-19 vaccine requirements:
Pfizer/BioNTech (Comirnaty®) — 2 doses Moderna (Spikevax) — 2 doses Johnson & Johnson/Janssen — single dose Novavax (Nuvaxovid™) – 2 doses
The following WHO-approved (emergency use listing, EUL) vaccines are accepted for meeting COVID-19 vaccine requirements:
AstraZeneca* (Vaxzevria) Covovax™* Covishield™* Covaxin®* Sinovac* (CoronaVac) Sinopharm/BIBP* CanSino-Convidecia
Non EUA Approved Vaccines: Sinopharm WIBP, CoviVac, CanSino-Convidecia, EpiVacCorona, Sputnik V
For Trojan Check compliance logic, go to: https://eshc-w2.usc.edu/display/IS/Trojan+Check
•
days before administering Pfizer booster If Pfizer booster received < 5 months after 2nd dose of primary series consider fully boosted and do not revaccinate