Vbcc june 2013

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JUNE 2013 VOL 4 NO 5

INTEGRATING ONCOLOGISTS, PAYERS, AND THE ENTIRE CANCER CARE TEAM www.ValueBasedCancerCare.com

Patient-Centered Oncology Medical Home in New Mexico Demonstrating Value Saving costs and increasing patient satisfaction By Caroline Helwick

Genomic Sequencing Assay Potentially a Game Changer By Caroline Helwick

Hollywood, FL—Genomic profiling of individual tumors represents a paradigm shift in oncology and holds great promise for patients, according to Gary Palmer, MD, JD, MBA, MPH, Senior Vice President, Medical Affairs and Commercial Development, Foun­ dation Medicine, who described this new genomic assay at the Third

Gary Palmer

Annual Conference of the Association for Value-Based Cancer Care. Before his position with Foundation Medicine, Dr Palmer led the development of the Oncotype DX Breast Cancer Assay for Genomic Health. In recent years, Foundation Medi­ cine has sequenced hundreds of breast Continued on page 9

ASCO Annual Meeting

Variations in Cancer Treatment Raise Average Cost of Care by $25,000 per Patient By Wayne Kuznar

Hollywood, FL— A community oncology medical home headed by Barbara L. McAneny, MD, Chief Executive Officer and Managing Partner of the New Mexico Cancer Center, Albuquerque, is a good example of how putting patients first can be good for patient care and good for the bottom line. Continued on page 8

ASCO Annual Meeting

Pazopanib: First Positive Maintenance Trial in Ovarian Cancer By Phoebe Starr

©2013 Engage Healthcare Communications, LLC

approximately 25% of the patients had treatment plans that did not conform to evidence-based standards. The finding “is an argument for decision support tools that are used at the point of care,” noted Dr Forastiere. “We can’t change this if we’re always at the back end.” Eviti is an independent health in­ for­ mation technology company that Continued on page 26

inside

A multikinase inhibitor delays relapse in advanced disease Chicago, IL—Previous trials of maintenance therapy for patients with ovarian cancer have failed to show improved survival. A study presented at the 2013 American Society of Clinical Oncology annual meeting is the first successful phase 3 trial in this setting, showing that the targeted therapy pazopanib (Votrient) extend-

Chicago, IL—Inappropriate deviation from evidence-based standards of care for cancer raises costs in excess of $25,000 per patient, stated Arlene A. Forastiere, MD, Senior Vice President of Medical Affairs at eviti, Inc, Philadelphia, PA, in a poster presented at the 2013 American Society of Clinical Oncology annual meeting. In Dr Forastiere’s review of oncology treatment plans for 2544 patients,

ed progression-free survival (PFS) by a median of 5.6 months in women with ovarian cancer. Women enrolled in the trial were free of disease after initial treatment with surgery and chemotherapy. “Pazopanib maintenance therapy prolongs the time the patient has

Continued on page 26

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ASCO ANNUAL MEETING . . . . . . . 26 Sorafenib effective in metastatic differentiated thyroid cancer

VALUE PROPOSITIONS . . . . . . . . . 6 Genetic testing for endometrial cancer

HEALTH POLICY . . . . . . . . . . . . . . 36 Medicare committee rejects new genetic tests for cancer

FROM THE EDITOR . . . . . . . . . . . Popularizing cancer as a topic of public discourse

CONFERENCE . . 8, 16 Pathways creating increasing value Value and quality of life in cancer care The changing landscape of oncology FDA UPDATE . . . . . . . . . . . . . 14,15 Xofigo approved for metastatic CRPC Mekinist and dabrafenib for advanced melanoma with BRAF mutations

ECONOMICS OF CANCER CARE . 36 High-cost lung cancer surveillance testing Disparities in guideline-based breast cancer care DRUG UPDATE . . . . . . . . . . . . . . . 40 Kadcyla approved for HER2-positive metastatic breast cancer


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