ISSN 2321 -9017 Volume 5, No.3, April - May 2017 Imane AllaliInternational et al., International Journal of Bio-Medical Informatics and e-Health, 5(3), April May 2017, 10- 14 Journal of Bio-Medical Informatics and– e-Health
Available Online at http://www.warse.org/IJBMIeH/static/pdf/file/ijbmieh01532017.pdf
A Moroccan Colorectal Cancer Database Imane Allali1,2, Souad Chaqsare4, Noureddine Boukhatem2, Leila Bouguenouch5, Jihane Querrach6, Mohamed Sekal7, Mohammed Adnane Tazi8, Abdelouahed Er-Raki9, Karim Ouldim5, Saaïd Amzazi1, Hassan Ghazal2,3* 1 Laboratory of Biochemistry & Immunology, Faculty of Sciences, University Mohammed V, Rabat, Morocco 2 Laboratory of Physiology and Genetics, Faculty of Sciences of Oujda, University Mohammed Premier, Oujda, Morocco 3 Polydisciplinary Faculty of Nador, University Mohammed Premier, Nador, Morocco 4 National Institute of Hygiene, Rabat, Morocco 5 Department of Molecular Genetics, University hospital Hassan II, Fez, Morocco 6 Department of Gastroenterology, University hospital Hassan II, Fez, Morocco 7 Department of Pathology, University hospital Hassan II, Fez, Morocco 8 National School of Public Health, Rabat, Morocco 9 National Institute of Oncology, Rabat, Morocco
ABSTRACT Colorectal cancer is one of the most common cancers in Morocco; the number of patients has been increasing over the last decade with the increase being attributed to different changes in the lifestyle. Here, we proposed to build a database for colorectal cancer of Moroccan patients for the purpose to capture all the data that may play a major role in cancer research and for a better managing of healthcare. This colorectal cancer database includes detailed information about family history, risk factors, eating habits and other information related to diagnoses and clinical notes. Patients with colorectal cancer were recorded between 2009 and 2013 from the National Institute of Oncology in Rabat and the Hospital University Center Hassan II in Fez. Data were collected from 525 patients; they were aged between 16–90 years, with 26.3% of colorectal cancer patients were ranging from 50 to 59 years. We observed that 46.1% of cancers were localized in the rectum, 31.1% of complaining symptoms were rectal bleeding and the most used treatment was surgery (62.2%). It is expected that this database will contribute to generating great information about colorectal cancer, provide important information for epidemiological studies and support colorectal cancer research in Morocco.
CRC in the Moroccan population. Accurate and extensive data on CRC patients are very important for the understanding of cancer etiology, clinical decisions and epidemiological studies. The purpose of this study is to create a colorectal cancer database that will be regional and national benchmarks for colorectal cancer care in Morocco. The CRC database includes detailed information about family history, risk factors, information related to diagnoses and clinical notes. This database is very useful for the analysis of the efficacy of diagnostic and therapeutic procedures and for the evaluation of clinical outcomes in real healthcare system that are essential for decision making in the management and the treatment. Additionally, our aim is that this database is expected to contribute to generating great information about colorectal cancer, to provide reliable records, to have easy data access with a better scientific reproducibility and interoperability between institutions in order to support colorectal cancer research in Morocco.
Keywords: Database, Colorectal cancer, Morocco.
The colorectal cancer database is a data integration platform and knowledge discovery system for the oncology and scientific research. It includes detailed information about family history, risk factors, eating habits and other information related to diagnoses and clinical notes as histopathology reports, radiotherapy and chemotherapy treatment data, administrative details such as route of admission and access to imaging information which will enable accurate cancer staging (Supplementary Figure 1). CRC database uses MySQL (My Structured Query Language) database management system to store the data. The PHP (Hypertext Preprocessor) and the HTML (HyperText Markup Language) programming language are used for retrieval and recording of data. For data safety, passwords were required to access the database to guarantee
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MATERIALS AND METHODS 2.1. Database
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INTRODUCTION Colorectal cancer (CRC) is the third leading cause of cancer related deaths in Morocco among cancers that affect both men and women behind breast and lung cancer [1-3]. The number of patients has been increasing over the last decade, the incidence was 10.4 per 100,000 individual in 2008 compared to 6.0 in 2005 according to the Cancer Registry of Rabat [2]. According to the same cancer registry, it estimated that 2,701 new cases must be diagnosed with CRC in 2008 in Morocco and 4,096 new cases are expected to be diagnosed in 2020 [2]. In spite of increased colorectal cancer patients, little is known about the factors that may influence the incidence of 10