Environmental Medicine by Andrew Lothian

Environmental Medicine Previously known as Clinical Ecology

Major Medical Studies That Show White-Blood-Cell Testing Is the Optimum Way to Test for Delayed Allergic Reactions to Foods and Chemicals Up until 1996 Medical Studies and Reports Using White-Blood-Cell Testing Introduction…………………………………………………………………………… Positive Studies and Reports with Positive Conclusions……………………………… Primarily Positive Studies with Negative Conclusions……………………………… Summary……………………………………………………………………………….. Environmental Medicine Major Studies in Environmental Medicine………………………………………… Books for the Public on Environmental Medicine…………………………………..

Major Medical Studies That Show Delayed Allergic Reactions to Foods and Chemicals Are the Primary or Partial Cause of Numerous Ailments Up until March 1992 unless otherwise noted.

Major Medical Studies, Books and Reports Based on Environmental Medicine Principles That Show Delayed Allergic Reactions Are The Cause of Numerous Symptoms: Addiction……………………………………………………………………………. Alcohol………………………………………………………………………………. Amino Acids………………………………………………………………………….. Arterial Disease……………………………………………………………………... Arthritis…………………………………………………………………………….. Asthma……………………………………………………………………………… Autism………………………………………………………………………………. Blood Abnormalities………………………………………………………………… Candida……………………………………………………………………………….. Chemical Sensitivity………………………………………………………………… Colitis……………………………………………………………………………….. Cohn’s Disease…………………………………………………………………….. Deliquency………………………………………………………………………….. Diet…………………………………………………………………………………. Drugs……………………………………………………………………………….. Eczema……………………………………………………………………………… Epilepsy…………………………………………………………………………….. Essential Fatty Acids……………………………………………………………….. Fatigue………………………………………………………………………………. Fibromyalgia………………………………………………………………………. Food Additives……………………………………………………………………… Gynecology………………………………………………………………………….. Hyperactivity………………………………………………………………………… Hypoglycemia………………………………………………………………………… Immunology………………………………………………………………………… Insects Studies……………………………………………………………………….. Inside Home…………………………………………………………………………… Irritable Bowel………………………………………………………………………..

Light………………………………………………………………………………….. Migraine……………………………………………………………………………… Nephrosis……………………………………………………………………………... Nutrition………………………………………………………………………………. Obesity………………………………………………………………………………... Otitis………………………………………………………………………………….. Outside Home…………………………………………………………………………. Physical and Psychological Complaints……………………………………………… Physician Books………………………………………………………………………. Physiological Mechanisms…………………………………………………………… Premenstrual Syndrome……………………………………………………………… Prenatal & Infant……………………………………………………………………… Sugar…………………………………………………………………………………. Tourette’s Syndrome…………………………………………………………………. Vitamin C……………………………………………………………………………. Miscellaneous Studies ……………………………………………………………… Unpublished Miscellaneous Studies…………………………………………………. British Books…………………………………………………………………………..

Positive Double-Blind Studies Studies Supporting Environmental Medicine Positive Single-Blind Diet Studies…………………………………………………..... Positive Double-Blind Diet Studies………………………………………………….... Positive Key Non-Blind Diet Studies…………………………………………………. Negative Double-Blind Diet Studies…………………………………………………... Positive Double-Blind Sublingual Studies Provocation/Neutralization Studies…………………………………………………… Negative Sublingual Provocation/Neutralization Studies……………………………… Provocation/Neutralization, Subcutaneous Treatment………………………………… Negative Studies of Provocation or Subcutaneous Food Testing………………………

Positive Double-Blind P.O. Pollen Studies……………………………………………. Negative Review Articles……………………………………………………………… Rebuttal Article………………………………………………………………………… Negative Position Papers……………………………………………………………… Positive Studies on Rinkel Method…………………………………………………… Negative Studies on Rinkel Method…………………………………………………...

Major Medical and Popular Books Supporting the Use of White-BloodCell Testing for Delayed Allergic Reactions Besides the following 71 positive medical studies and reports published on whiteblood-cell testing, there are fourteen popular books, and one medical textbook, that explain its value and the importance of delayed food and chemical allergies. Lawrence D. Dickey, MD, edited the medical textbook, Clinical Ecology. In chapter 47, William Bryan, MD, and his wife Marian Bryan wrote the following about the cytotoxic test: “After fifteen years of use on almost five thousand patients … many and even some spectacular cures have been accomplished. Others using the test have verified these observations which re-emphasize the importance of making specific diagnosis of allergy to food and of its subtle effects on many diseases of unknown etiology. “The authors now consider the test as both practical and dependable both in allergy and as a factor affecting the immune status of many patients …. By direct microscopic observation of the action of serum and food extracts on the activity and viability of the neutrophilic leukocytes, an objective and reliable test for food allergy may be achieved …. The reason for bringing this to the attention of otorhinolaryngologists, allergists and other physicians is that, as yet, there is no other way of diagnosing multiple specific food allergies which play such important roles in the obscure etiologies of many symptoms and diseases among which are many of our therapeutic failures.” Published in l976 by Charles C. Thomas, $60.00. The first popular book on food allergies and white-blood-cell testing was, The Food Connection, by psychiatrists David Sheinkin, MD, Michael Schachter, MD, and Richard Hutton. This 1979 book compares many different methods of testing for food allergies. The authors wrote that, “Cytotoxic testing demands a minimal amount of time and effort by the patient … is efficient … perfectly safe (no pain or harm to the patient) … reactions are relatively objective, can be repeated if necessary with little hardship for the patient … the test picks up some latent food sensitivities that are sometimes missed by other types of tests.” Published by the Bobbs-Merrill Company, $10.00. In paperback as, Food, Mind and Mood. Schachter has been using the Prime Test since 1992. In the book, Dr. Wright’s Book of Nutritional Therapy, Jonathan V. Wright, MD, wrote “Some physicians use cytotoxic testing. In this test, white blood cells are exposed to food antigen solutions and disintegrate more readily if there is an allergy. When done ®

by well trained individuals, this test may be very helpful.” Published in 1979 by Rodale Press, $18.00. In 1980, I wrote the first edition of Quality Longevity. A highlight is “Discovering your health-damaging foods by using an accurate white-blood-cell test for delayed food allergies is the first step toward removing the cause of a broad range of health problems. In addition, selecting foods that are low in fat, moderate in protein and high in complex carbohydrates will enable you to improve your health further. It is now possible to continually enjoy good health and add many enjoyable years to your life. “Aerobic and strength exercise are also necessary to regain and maintain health. Also, your optimum combination of non-allergenic supplements to fulfill your unique vitamin, mineral and other requirements should be analyzed and selected after you have eaten your compatible foods for one month. “The Quality Longevity Program brings together, for the first time, the effective parts of the proven health approaches. The combined effect of these breakthroughs enables you to become free of most current symptoms and future ailments. You will be able to exceed greatly the average levels of health and longevity.” Published by Preventive Care Center, Inc., $28.00. In 1980, Dr. C. Keith Conners wrote, Food Additives and Hyperactive Children. Conners demonstrated the efficacy of the cytotoxic test by using the double-blind technique. He concluded, “The test predicts which foods will show allergic response … [it] is both reliable and valid.” Published by Plenum, $29.50. In the book, Brain Allergies: The Psycho-nutrient Connection, by psychiatrist William H. Philpott, MD, and Dwight K. Kalita, PhD, Philpott wrote that the cytotoxic test is one test which should be used because it gives “… microscopic evidence of the blood reacting to foods, chemicals, and inhalants ….” He also wrote, “… insulindependent juvenile diabetics cannot be fasted. In those cases … the initial reliance of reactivity to a food or substance comes from the intradermal serial-dilution provocative test supplemented by information from the cytotoxic test ….” Published in 1980 by Keith Publishing Inc., $15.00, paperback, $12.95. Don Mannerberg, MD, and June Roth, MS, wrote, Aerobic Nutrition in 1981. Mannerberg had learned the importance of the 10–10–80 principle while working for Nathan Pritikin as the Director of Medical Services at the Pritikin Longevity Center. He later learned about the importance of delayed food allergies from Dr. Randolph and became the second person to combine these approaches and then write a book about these breakthroughs. Dr. Mannerberg and Roth wrote “As many as thirty years ago, Dr. Theron Randolph of Chicago was claiming that food and environmental allergies were causing behavioral disorders. Many doctors all over the country have followed his lead and have developed techniques to uncover these sensitivities. They include intradermal testing, sublingual testing, and the elimination diet. Some sophisticated methods have been developed lately using cytotoxic testing ….” Published by E. P. Dutton in hardcover and Berkley Books in paperback, $3.95. The Nutritional Outline for the Professional was written in 1983 by urologist James F. Balch, Jr, MD, and Phyllis A. Balch, NC. They summarized their study of different types of allergy testing by concluding, “A cytotoxic test is the best method to identify your allergies ….” Published by Good Things Naturally, $15.00. In 1990 the first

edition of their best selling book, Prescription for Natural Healing, they recommend Advanced Health Center’s (now called Preventive Care Center) test kits for food allergies. Avery Publishing, $16.95. The Food Sensitivity Diet, by Doug Kaufmann and Racquel Skolnik, was published in 1984. They wrote, “By far, the easiest way to isolate food sensitivities is by taking the cytotoxic test. This test requires a small blood sample prepared and then placed on slides. Each of your slides is preinoculated with a different food substance and then placed under a microscope and observed by a technician. The technician can observe some of these food substances killing your white blood cells ….” Published by Freundlich Books, $l5.95. In paperback by Paper Jacks, $3.95. Robert Buist, PhD, wrote, Food Intolerance in 1984. His PhD is in Medicinal Chemistry and Pharmacology. About the cytotoxic test he states, “The other advantages of the test are the minimal time required and the lack of discomfort for the patient. This is especially important when testing psychiatric patients. It is also safe and objective from the patient’s point of view.” Published in Australia by Harper and Row; in the U.S. by Prism Press, $7.95. The Allergy Connection by Barbara Paterson was published in 1985 in England. She reports on Dr. N. P. D. Downing’s successes using the cytotoxic test: “Dr. Downing also considers that cytotoxic testing offers a possible solution to those who, for one reason or another, are unable to embark on elimination diets … the accuracy of cytotoxic testing varies, but averages 80% …. he considers that it can be a very useful guide, and that – carried out by careful technicians, and translated by a skilled medical advisor – it can attain a high degree of accuracy.” Published by Thorsons Publishers Inc., $8.95. Dr. George T. Lewith and Dr. Julian N. Kenyon wrote, Clinical Ecology, which was published in England in 1985. After mentioning the difficulties and costs associated with the cytotoxic test, they state, “The correlation between food and/or chemical avoidance and clinical improvement is high for cytotoxic testing …. It is, however, less expensive than the RAST and much more clinically useful.” Published in England by Thorsons Publishers, $7.95. Stuart M. Berger, MD, came to California and learned about the importance of delayed food allergies and the cytotoxic test from an associate of mine and went on to use the approach in his New York office. In his l985 best selling book, Dr. Berger’s Immune Power Diet, he wrote, “Cytotoxic testing is a valuable tool in screening patients for food sensitivities. The test can be done quickly in the laboratory using only one blood sample from each patient, so there is no unnecessary evoking of possible allergic reactions. The test uses a drop of blood which is then exposed to various food extracts; by observing the patient’s white blood cells’ reactions to different food extracts, hundreds of foods can be tested quickly and efficiently for their immune-toxic potential. I have had superb results using this test to evaluate thousands of patients.” Published by New American Library, $14.95. In 1988 Robert Atkins, MD, wrote, Dr. Atkins’ Health Revolution. Unfortunately, Atkins does not understand the science of macronutrient balancing, but he does understand the importance of avoiding foods that kill your white blood cells. After testing several thousand patients with the original cytotoxic test, he concluded, “With a good technician, the results of the cytotoxic test can be quite accurate and reproducible.

The test has the advantage of being less expensive than most of the others; therefore, it is readily applicable for routine testing.” Published by Houghton Mifflin Company, $18.95. In England in 1990, Jonathan Brostoff, MA, DM, FRCP, DSc and Linda Gamlin wrote, The Complete Guide to Food Allergy and Intolerance. Brostoff is a consulting physician in allergy at Middlesex Hospital Medical School. While pointing out some of the problems experienced with the original cytotoxic test, the doctor writes, “Scientific appraisals of the cytotoxic test show that food extracts do sometimes affect the white blood cells … a recent study under carefully controlled conditions produced 65-70 per cent accuracy.” Published by Bloomsbury Publishing, London, England, $12.00. Optimal Wellness by Ralph Golan, MD, was published in 1995. He writes, “The cytotoxic test, a blood test, determines if blood cell damage or destruction occurs when the cells are exposed to the allergic or toxic substance…. Done competently by an experienced technician, the cytotoxic test is considered by many clinicians to be a reliable and very economical test.” Published by Ballantine Books, $20.00. A summary and conclusion comes after the following listing.

Major Scientific Studies and Reports on White-Blood-Cell Testing 1917 through August 1996 The following chronological list of published medical studies identifies research that has been suppressed, ignored or misrepresented by most conventional allergists. This list is based on the work of several researchers and is believed to be complete. It includes studies and reports. Studies that are known not to have been peer-reviewed are noted. The others are peer-reviewed or are older studies performed when that process was not considered necessary. Historically, the editorial board or the editor did the reviewing. In the past, it was possible to have a study published which was not in the best financial interest of conventional medical doctors or drug companies which advertised in the journal. This is no longer the case because every article is now reviewed by a committee called the “peer-review board” before it can be published. This stifling of new, helpful information by conventional doctors is rampant. However, it also happens in other sciences. A report in Scientific American by Geoffrey Burbridge, professor of physics at the University of California, San Diego, clearly summarized the problem. He wrote, “Those of us who have been around long enough know that the peer-review and the refereeing of papers have become a form of censorship.” It is interesting that all of the positive studies were done by people who had experience with white-blood-cell testing, while all the ‘negative’ studies were done by people who relied on conventional allergy testing and had no previous experience with white-blood-cell testing. The following list does not include opinion papers. People who have no experience with the test, but used selected comments from the ‘negative’ studies and reports wrote several negative opinion papers on white-blood-cell testing.

To read the entire text of several of the following studies, visit our website at PreventiveCare.com.

Major Positive Studies and Reports with Positive Conclusions (71) 1

Pappenheimer AM. Experimental studies upon lymphocytes. The action of immune sera upon lymphocytes and small thymus cells. J Experimental Med. l9l7;26:l63.

Vaughn WT. The leucopenic index as a diagnostic method in the study of food allergy. J Lab Clin Med. 1936;21:1278-1288.

Mallery Jr OT, Randolph TG. Effect in vitro of propylene glycol on leukocytes. J Lab Clin Med. 1944;Feb 29:203.

Randolph TG, Rawling FFA. Blood studies in allergy: V. Variations of total leukocytes following test feeding of foods; an appraisal of individual food test. Annuals of Allergy. 1946;May-June 4:163-178.

Randolph TG. Blood studies in allergy: IV. Variations in eosinophils following test feeding of foods. J Allergy. 1947; May 18:199-211.

Squier TL, Lee HJ. Lysis in vitro of sensitized leukocytes by ragweed antigen. J Allergy. l947;18:l56-l63.

Pettay O. Preliminary report on the use of in vitro leukocytolysis as a test in allergy. (Abstract) Scandinavian J Clinical Laboratory Investigation. 1952;4:77.

Waksman BH. Specific white cell lysis produced by combination of rabbit antiserum to purified protein (ovalbumin, bovine gamma globulin) with homologous antigen: the role of the nonprecipitating antibody. Immunology. 1953;70:33l-334.

Hartman JD, Hock WC. Changes in blood leucocytes resulting from antigen antibody reactions. American J Psychology. 1955;l83:214-220.

10 Black AP. A new diagnostic method of allergic disease. Pediatrics. l956;l7:716724. 11 Bryan WTK, Bryan MP. The application of in vitro cytotoxic reactions to clinical

diagnosis of food allergy. [Non-peer]. Laryngoscope. 1960;70:8l0-824. 12 McEwen LM. A method for the maintenance of leucocytes in their globular form. J Physiology. 1966;184:3-5. 13 Speirs RS. The action of antigen upon hypersensitive cells. Ann New York Academy Science. 1964;ll3:8l9-824. 1 4 Ruddle NH, Waksman BH. Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. J Exp Medicine. l968;Dec 128. 15 Bryan WTK, Bryan MP. Cytotoxic reactions and the diagnosis of food allergy. Laryngoscope. 1969;79:l453-l472. 1 6 Bryan WTK, Bryan MP. Cytotoxic reactions in the diagnosis of food allergy. Otolaryngologic Clinics of North America. 1971;4:523-534. 17 Bryan WTK, Bryan MP. Clinical examples of resolution and some idiopathic and other chronic diseases by careful allergic management. Laryngoscope. 1972;82:l23ll238. 18 Baker SP. Allergic respiratory tract disease. Medical J Australia. 1973;l:l26-l27. 1 9 Ulett GA, Perry SG. Cytotoxic food testing in alcoholics. Alcoholism. 1974;35:930-942.

Quart J Studies

20 Ulett GA, Perry SG. Cytotoxic food testing and leukocyte increase as an index to food sensitivity. [Non-peer]. Ann Allergy. 1974;33:23-32. 21 Ulett GA, Perry SG. Cytotoxic testing and leukocyte increase as an index to food sensitivity. II. Coffee and tobacco. Ann Allergy. 1975;34:l50-l60. 22 Hughes EC. Chemically defined diet in the diagnosis and management of allergy or food intolerances. I. With a group of sensorineural hearing impaired. Trans Am Acad Ophthalmol and Otolaryngol Allergy. 1975;l5:60-71. 23 Bryan WTK, Bryan MP. Diagnosis of food allergy by cytotoxic reactions. Trans Am Soc Ophthalmol and Otolaryngol Allergy. 1976;15:14-23.

2 4 Bickmore JT. Leukocyte test for food allergies: its application toward clinical practice. Trans Am Soc Ophthalmol Otolaryngol Allergy. 1976;l6:l0l-l08. 25 Updegraff TR. Food allergy and cytotoxic tests. Ear Nose Throat J. 1977;56:450459. Also Trans Am Soc Ophthalmol and Otolaryngol Allergy. l977;16:48-64. 26 Hughes EC. Chemically defined diet in the diagnosis of food sensitivities. II. With a panel of seriously sensitive patients. Trans Am Soc Ophthalmol Otolaryngol Allergy. l977;17:43-65. 27 Boyles JH. The validity of using the cytotoxic food test in clinical allergy. Ear Nose Throat J. l977;56:35-43. 2 8 Duncan RB, Duncan TD. Otolaryngeal allergy in Wellington l97l-l975. New Zealand Med J. l977;85:45-52. 29 Oehling A, Martin-Gil D, Jerez J, Subira ML. In vitro diagnosis of food allergy. Allergol Immunopathol (Madr.). l978;6:l53-l6l. 3 0 Rubin JL, Griffiths RW, Hill HR. Allergen-induced depression of neutrophil chemotaxis in allergic individuals. J Allergy Clin Immunol. l978;62:30l-308. 31 Hughes EC. Use of a chemically defined diet in the diagnosis of food sensitivity and the determination of offending foods. Ann Allergy. 1978;40:393-398. 32 Hughes EC, Gottschalk GH. Comparison of cytotoxic test for food sensitivities with food challenge experience: effect of sample timing. Trans Am Acad Ophthalmol Otolaryngol Allergy 1978;18:39-51. 33 Hughes EC, Oettinger L, Johnson F, Gottschalk GH. Case report: A chemically defined diet in diagnosis and management of food sensitivity in minimal brain dysfunction. Ann Allergy. l979;42:l74-l76. 3 4 Ulett GA. Food allergy: Cytotoxic testing and the central nervous system. Psychiatric J Univ Ottawa. l980;5:l00-l08. 35 Stavish GE. The clinical aspects of the cytotoxic test. [Non-peer]. The Bion. l980. 36 Holopainen E, Palva T, Stenberg P, Backman A, Legti H, Ruokonen J. Cytotoxic

leukocyte reaction. Acta Otolaryngol l980;89:222-226. 37 Ruokonen J, Holopainen E, Palva T, Backman A. Secretory otitis media and allergy with special reference to the cytotoxic leucocyte test. Allergy. l98l;36:59-68. 3 8 Ruokonen J. Reactions in the cytotoxic leucocyte test. Allergol Immunopathol. (Madr.) l98l;9:28l-288. 39 Hopkins JM, Tomlinson VS, Jenkins RM. Variation in response to cytotoxicity of cigarette smoke. Br Med J. l98l;283:l209-12ll. 40 West WG. Food sensitivities through the cytotoxic test. The Bion. l98l. 41 Stavish GE. Clinical application of cytotoxic test as it relates to comprehensive ecological investigation. The Bion. l98l. 42 Stromp MA. The beauty of the cytotoxic test. Preventative Medicine Forum. Fall l98l. 43 Bienveniste J. The human basophil degranulation test as an in vitro method for diagnosis of allergies. Clinica Allergy. l98l;ll:l-ll. 4 4 Trevino RJ. Immunologic mechanisms in the production of food sensitivities. Laryngoscope. l98l;9l:l9l3-l936. 45 Cheung G, Plechner AJ. Diagnosis of canine and feline food sensitivities: a new method. New Methods. l982; 5:20-25. 46 Hughes EC, Gottschalk GH, Kaufmann D. Effect of time of blood sampling on in vitro tests for food sensitivities. Ear Nose Throat J. l982;61:8l-87. 47 Ruokonen J, Paganus A, Lehti H. Elimination diets in the treatment of secretory otitis media. Int J Pediatr Otorhinolaryngol. l982;4:39-46. 48 King I. The cytotoxic test, uncovering hidden food allergies. Inter J Holistic Health & Medicine. 1983;2:30-32 49 Hopkins JM, Gorecka D. Tough cells and old age. Lancet. l983;ii:ll70-ll73.

50 Palva T, Legtinen T, Malmberg H. Separation of granulocytes for the cytotoxic leucocyte test. Laryngoscope. l983;93:242-244. 5 1 Podleski WK. Cytodestructive mechanisms provoked by food antigens. Antibody-dependent allergic autocytotoxicity. Allergy. l985;40:l66-l72.

II.

52 Cheraskin E, Allen J, Zavik J. The psychotherapeutic implications of cytotoxic testing. J Orthomolecular Psychiatry. l985;l4:l28-l35. 53 Podleski WK. Cytodestructive mechanisms provoked by antigens. I. Direct, allergic autocytotoxicity. Allergy. l985;40:l57-l65. 54 Podleski WK. Spontaneous allergic autocytotoxicity in bronchial asthma associated with food allergy. American J Medicine. l986;8l:437-442. 55 Lovendale M. Nurses help doctors find the missing diagnosis. [Non-peer]. California Nursing Today. 1986 May. 56 Pasula MJ. A possible new whole blood assay for delayed hypersensitivity reaction. AMT CE Supp. 1988;July l78-l79. 57 Fell PJ, Brostoff J, Pasula MJ. High correlation of the ALCAT test results with double-blind challenge (DBC) in food sensitivity. Ann Allergy. 1989;62:253. 58 Sandberg DH, Pasula MJ. A comparison of the ALCAT test for food reactions amongst 2 population sub-groups. Ann Allergy. 1989;62:271. 59 Fell PJ, Sandberg DH, Pasula MJ. Inhibitory effect of sodium Cromoglycate on granulocyte response to food antigens in-vitro. Ann Allergy. Nov 1990;10-14. 60 Jackson JA, Riordan HD, Neatherly S. Comparison of two cytotoxic food sensitivity tests. American Clinical Laboratory. 1991;March 20-21. 6 1 Fell PJ, Soulsby S, Brostoff J. Cellular responses to food in irritable bowel syndrome. An investigation of the ALCAT test. J Nutritional Medicine. 1991;2:143149. 6 2 Wataha JC, Craig RG, Hanks CT. Precision of new methods for testing alloy cytotoxicity. Dental Materials. 1992;Jan 8(1):65-70.

6 3 Solomon B. The ALCAT Test: A guide and barometer in the therapy of environmental and food sensitivities. Environmental Medicine. 1992;9(2). 64 Pasula MJ. The ALCAT test: in vitro procedure for determining food sensitivities. Folia Medica Cravoviensia. 1993;34(1-4):153-157. 65 Sinkovics J, Horvath J. Cytotoxic human lymphocytes: from in vitro testing (1970s) to immunotherapy (1990s). Acta Microbiologica Hungarica. 1993;40(3):165-179. 66 Goguen B, Kedersha N. Clonogenic cytotoxicity testing by microdrop encapsulation. Nature. May 1993;263(6425):189-190. 6 7 Lam KM. A cytotoxicity test for the detection of Campylobacter jejuni toxin. Veterinary Microbiology. 1993;May 35(1-2):133-139 68 Wang XM, Terasaki PI, Rankin GW Jr, Chia D, Zhong HP, Hardy S. A new microcellular cytotoxicity test based on calcein AM release. Human Immunology. 1993;Aug 37(4):264-270. 69 HĂ¸j L. Food intolerance in patients with angioedema and chronic urticaria: An investigation by RAST and ALCAT test. European J of Allergy and Clinical Immunology. 1995;26(50). 70 HĂ¸j L. Diagnostic value of ALCAT test in intolerance to food additives compared with double-blind placebo-controlled (DBPC) oral challenges. J Allergy and Clinical Immunology. 1996;97(1)3. 71 Kaats GR, Pullin D, Parker LK. The short term efficacy of the ALCAT test of food sensitivities to facilitate changes in body composition and self reported disease symptoms: A randomized controlled study. Amer J Bariatric Medicine. 1996;Spring 18-23.

Primarily Positive Studies with Negative Conclusions (6) 1

Franklin W, Lowell FC. Failure of ragweed pollen extract to destroy white cells from ragweed-sensitive patients. J Allergy. 1949;20:375-377.

Chambers VV, Hudson BH, Glaser J. A study of the reactions of human polymorphonuclearleucocytes to various allergens. J Allergy. 1958;29:93-102.

Lieberman P, Crawford L, Bjelland J, C[a]nnell B, Rice M. Controlled study of the cytotoxic food test. JAMA. 1975;231:728-730.

Benson TE, Arkins JA. Cytotoxic testing for food allergy: evaluation of reproducibility and correlation. J Allergy Clin Immuno. 1976;58:471-476.

King WP. Testing for food allergy: a statistical comparison of cytotoxic and intracutaneous tests. [Non-peer]. Laryngoscope. 1978;88:1649-1659.

Lehman CW. The leucocytic food allergy test: a study of its reliability and reproducibility. Effect of diet and sublingual food drops on this test. [Non-peer]. Ann Allergy. 1980;45:150-158.

Summary The positive studies and reports were performed by doctors and preventive care specialists who understand the importance of the original definition of allergy. They had used the cytotoxic test for an extended length of time and became accomplished in the performance of the test before they did their studies and wrote their reports. The ‘negative’ studies were done by conventional allergists who use the limited IgE definition of allergy. They test their patients with skin tests and treat them with years of allergy shots. Doctors who had not used the cytotoxic test before, and had no experience in making the kits or performing the test, did all these ‘negative’ studies. Their studies are simply reports on their first try to perform a complex procedure. It is noteworthy that two studies with negative conclusions obtained good reproducibility (something that cannot be obtained with conventional skin tests). Because white-blood-cell testing for delayed allergies discredits the conventional allergist’s beliefs about what allergies are and threatens their income, it is not hard to see why they did not appreciate the results they were receiving from the cytotoxic test. Numerous ailments are causing painful suffering for millions of people. Rapidly growing medical costs are bankrupting people, businesses, insurance companies and the nation as a whole. Both logic and compassion cry out for the wide use of a cost-effective and accurate white-blood-cell test and the improved diets that follow. Most of the conventional approaches, such as drugs, surgeries and allergy shots, harm people and deplete their life savings. Allergy tests, other than white-blood-cell testing, miss many delayed allergic reactions. An accurate white-blood-cell test is the most effective, cost efficient way to discover delayed food and chemical allergies. These are just two of the reasons why conventional allergists dislike this blood test. According to the Journal of Allergy and Applied Immunology, allergic reactions are probably the most frequently unrecognized cause of illness in the U.S.

John H. Boyles, Jr, MD, is a past president of the Otolaryngology Allergy Academy and the American Academy of Environmental Medicine. He is the author of a peerreviewed study, published in a leading medical journal, which used white-blood-cell testing for discovering delayed food allergies [27]. The study concluded, “We believe the results of this study unequivocally validate the use of the cytotoxic test as a clinical tool.” By taking the modern white-blood-cell test, and using the individualized diet it makes possible, you can remove the underlying causes of most symptoms without causing any harm while reducing your medical bills. This approach will put a lot of doctors out of work, which is necessary if we are going to reduce healthcare costs. By learning this information, you have gained a better understanding of allergy than most conventional allergists have.

Environmental Medicine Major Studies – Environmental Medicine (6) 1

Randolph TG, Yeager LB (1947). Incidence of Allergy to Major Foods. Journal of Laboratory & Clinical Medicine. 32:1547.

Randolph TG (1950). Symposium on Food Allergy; Concepts of Food Allergy Important in Specific Diagnosis. J Allergy. 21:471.

Randolph TG (1965). An Ecologic Orientation in Medicine: Comprehensive Environmental Control in Diagnosis and Therapy. Annals of Allergy. 23:7.

Randolph TG (1976). Historical Development of Clinical Ecology. Clinical Ecology. Dickey LD, Ed. Thomas, Springfield, IL.

Randolph TG (1977). Allergies and the Family Practitioner. New Dynamics of Preventive Medicine. 3:73.

Randolph TG (1979). Food Addiction (Chronic Food Allergy) – The Apparent Basis of Other Addictions. 35th Annual Congress of the American College of Allergists. (Abstract).

Major Books for the Public – Environmental Medicine (21) 1

Bell I. Clinical Ecology. Commonweal Research Institute, Box 3168, Bolinas, CA 94924

Forman R. How To Control Your Allergies. Larchmont Books, 390 Fifth Avenue, New York, NY 10018

Gerrard J. Food Allergy – New Perspectives. Charles C. Thomas Publishers. Bannerstone House, East Lawrence Ave., Springville, IL

Golos N. Environmental Medicine. James O'Shea. Francis Waickman Keats Publishing, 27 Pine Street, New Canaan, CT 1987

Kalita D. Brain Allergies. Keats Publishing Co., 27 Pine Street, New Canaan, CN 06840

Lee CH. Allergy Neutralization. Tri Sigma Press, Box 5098, St. Joseph, MO 64505. 1987.

Levine A, Zellerbach M. Type 1-Type 2 Allergy Relief Program. JB Tarcher, Inc., 9110 Sunset Blvd., Los Angeles, CA 90069

Lovendale M. Quality Longevity. Preventive Care Center, 34146 Selva Rd. Suite 200, Monarch Beach, California, 92629 1980 / 2003

Lynes B. The Cancer Cure That Worked!. Marcus Books, P.0. Box 327 Queensville, Ont. Canada. LOG IRO. 1987.

10 Lynes B. The Healing of Cancer. Marcus Book, P.O. Box 327 Queensville, Ont. Canada 1987 11 Mackarness R. Eating Dangerously, The Hazards of Hidden Allergies. Harcourt, Brace, Jovanovich, New York. 1976. 12 Mackarness R. Not All In The Mind. Pan, London. 1976. 13 MacLennan J. Common Sense for the Sensitive. Human Ecology Foundation of Canada, 465 Highway 8, Dundas, Ontario L9H 4V9 14 Randolph T. An Alternative Approach to Allergies. Harper & Row Publishers, 10 East 53rd Street, New York, NY 10022 1 5 Randolph T. Allergies: Your Hidden Enemy. Wellingborough, Northamptonshire. 1980.

Thorsons Publisher Ltd.,

16 Rapp DJ. Allergies And Your Family. Practical Allergy Research Foundation, P.O. Box 60, Buffalo, NY 14223-0060 17 Rapp DJ. The Impossible Child – In School, At Home. Practical Allergy Research Foundation, P.O. Box 60, Buffalo, NY 14223- 0060 18 Rinkel HJ, Randolph TG, Zeller M. Food Allergy. Thomas, Springfield, IL, 1951.

19 Rogers S. The E.I. Syndrome. Box 3161. 3502 Brewerton Rd., Syracuse, NY 13220 20 Sahley B. The Anxiety Epidemic. Watercress Press, San Antonio, TX. 1986. 21 Small B, Small B. Sunnyhill-The Health Story of the '80’s. Small & Associates. Publishers. RR #1. Goodwood. Ontario, OC IAO

Major Medical Studies That Show Delayed Allergic Reactions to Foods and Chemicals Are the Primary or Partial Cause of Numerous Ailments Addiction Major Studies – Addiction (8) 1

Randolph TG (1956). Descriptive Features of Food Addiction; Addictive Eating and Drinking. Quarterly Journal of the Study of Alcohol. 17:198.

Randolph TG (1957). Food Addiction and Alcoholism. Journal of Laboratory & Clinical Medicine. 50:940.

Randolph TG (1964). Food Addiction, Obesity and Alcoholism. International Journal of Social Psychology. Special Edition No. 4, 1st International Congress of Social Psychology. 70.

Randolph TG (1970). Food Addiction: A Factor in the Development of Other Addictive Phenomena. Journal of Laboratory & Clinical Medicine. 76:991.

Randolph TG (1978). Specific Adaptation. Annals of Allergy. 40:333.

Randolph TG (1978). Food Addictions (Chronic Food Allergy) – The Apparent Basis of Other Addictions. Clinical Research. 26:700A.

Randolph TG (1979). Food Addiction (Chronic Food Allergy) – The Apparent Basis of Other Addictions. 35th Annual Congress of the American College of Allergists. (Abstract).

Randolph TG (1979). The Scope of Food & Chemical Allergy/Addiction. Continuing Education for The Family Physician. 11:3,63.

Alcohol Major Studies – Alcohol (4) 1

Randolph TG (1950). The Mechanism of Chronic Alcoholism. Laboratory & Clinical Medicine. 36:978.

Journal of

Randolph TG (1957). Food Addiction and Alcoholism. Journal of Laboratory & Clinical Medicine. 50:940.

Randolph TG (1964). Food Addiction, Obesity and Alcoholism. International Journal of Social Psychology. Special Edition No. 4, 1st International Congress of Social Psychology. 70.

Randolph TG (1976). The Role of Specific Alcoholic Beverages. Clinical Ecology. Dickey LD, Ed. Thomas, Springfield, IL. 321.

Amino Acids Major Books – Amino Acids (2) 1

Braverman E, Pfeiffer, C. The Healing Nutrients Within: Facts, Findings, and New Research on Amino Acids. Keats Publishing, New Canaan, CT. 1987.

Sahley BJ. The Natural Way to Control Hyperactivity, with Amino Acids and Nutrient Therapy. The Watercress Press, San Antonio, TX. 1968.

Arterial Disease Major Studies – Arterial Disease (15) 1

Harkavy J (1970). Cardiac Manifestations Due To Hypersensitivity. Annals of Allergy. 28:242-251.

Rea WJ (1976). Environmentally Triggered Thrombophlebitis. Annals of Allergy. 37:102-109.

Rea WJ, Bell IR, Smiley RE (1977). Environmentally Triggered Large-Vessel Vasculitis. Annals of Allergy. 38:245-251.

Rea WJ (1977). Environmentally Triggered Small Vessel Vasculitis. Annals of Allergy. 38:245.

Rea WJ (1978). Environmentally Triggered Cardiac Disease. Annals of Allergy. 40:243-251.

Rea WJ, et al (1978). Food and Chemical Susceptibility After Environmental Chemical Overexposure: Case Histories. Annals of Allergy. 41:101-110.

Rea WJ (1978). Environmentally Triggered Cardiac Disease. Annals of Allergy. 40:243-251.

Rea WJ, Suits CW (1980). Chapter: Cardiovascular Disease Triggered By Foods and Chemicals. Food Allergy: New Perspectives. (Gerrard, JW, eds.). Springfield: Charles C. Thomas.

Rea WJ (1981). Recurrent Environmentally Triggered Thrombophlebitis. Annals of Allergy. 47:338-344.

1 0 Rea WJ, Mitchell MJ (1982) Chemical Sensitivity and The Environment. Immunological Allergy Practice. 5:21-31. 11 Gaby A (1983). Nutritional Factors In Cardiovascular Disease. Journal of Holistic Medicine. 5. 12 Rea WJ (1984). Elimination of Oral Food Challenge Reaction By Injection of Food Extracts: A Double-Blind Evaluation. Archives of Otolaryngology. 110:248-252. 13 Rea WJ, Butler JR, Laseter JL, DeLeon IR (1984). Pesticides and Brain-Function Changes in a Controlled Environment. Archives of Clinical Ecology. 2(3):145-150. 14 Rea WJ, Brown OD (1985). Mechanisms of Environmental Vascular Triggering. Clinical Ecology. 111:122-127. 15 Rapp DJ (1986). Chapter: Sublingual Testing and Treatment. Food Allergy and Intolerance. (Brostoff, J, Challacombe, S, eds.). Philadelphia: Bailliere Tindall-W.B. Saunders. Major Books – Arterial Disease (7) 1

Harkavy J. Vascular Allergy and It’s Systemic Manifestations. Washington: Butterworths. 1963.

Leonard JN, Hofer JL, Pritikin N. Live Longer Now: The First Hundred Years of Your Life: The 2100 Program. Berkley Publisher Group, 1974 –1986.

McDougall J. The McDougall Program. 19XX.

McDougall J. McDougall Program for a Healthy Heart: A Life-Saving Approach to Preventing and Treating Heart Disease. 19XX.

Ornish D. Dr. Dean Ornish’s Program for Reversing Heart Disease: The Only System Scientifically Proven to Reverse Heart Disease Without Drugs or Surgery. 19XX.

Pritikin N. The Pritikin Program: 28 Days to a Longer, Healthier Life. Market Paperback, 1980.

Whitaker J. Reversing Heart Disease. 19XX.

Arthritis Major Studies – Arthritis (8) 1

Randolph TG (1976). Ecologically Oriented Rheumatoid Arthritis. Clinical Ecology. Dickey LD, Ed. Thomas, Springfield, IL. 201.

Finn R, Cohen HN (1978). Food Allergy: Fact or Fiction: Lancet. 1:426-428.

Parke AL, Hughes GVT (1981). Rheumatoid Arthritis and Food. A Case Study. British Medical Journal. 282:2027-2029.

Mandell M, Conte A (1982). The Role of Allergy in Arthritis, Rheumatism and Polysymptomatic Cerebral, Visceral, and Somatic Disorders: Double-Blind Study. Journal of International Academy of Preventive Medicine.

Little CH, Stewart AG, Hennessy MR (1983). Platelet Serotonin Release in Rheumatoid Arthritis: A Study in Food-Intolerant Patients. Lancet. :297.

Kroker G, et al (1984). Arthritis Study. Clinical Ecology. 3:145.

Finn R, Battock TM (1985). A Critical Study of Clinical Ecology. The Practitioner. 229:883-885.

Darlington LG, Ramsey NW, Mansfield JR (1986). Placebo-Controlled, Blind Study of Dietary Manipulation Therapy in Rheumatoid Arthritis. Lancet. 2:236-238.

Major Books – Arthritis (7) 1

Alexander D. Arthritis and Common Sense. The Witkower Press, P.O. Box 2296, Bishop's Corner, West Hartford, CT 06117. 1987.

Dong CR, Banks J. The Arthritic’s Cookbook. Bantam Books, 666 Fifth Avenue, New York, NY 10019. 1973.

Dong CR, Banks J. The Arthritic’s Cookbook. Bantam Books, 666 Fifth Avenue, New York, NY 10019. 1979.

Fredericks C. Arthritis: Don’t Learn to Live With It. The Putnam Publishing Group, 200 Madison Ave., New York, NY 10016. 1981.

Keough C. Natural Relief for Arthritis. By the editors of Prevention Magazine. Pocket Books, New York. 1986.

Mandell M. Dr. Mandell’s Lifetime Arthritis Relief System. Coward-McCann, 200 Madison Ave., New York, NY 10016. 1983.

Lovendale M. Quality Longevity. Preventive Care Center, 34146 Selva Road, Suite 200, Monarch Beach, CA 92629. 2004.

Asthma Major Studies – Asthma (3) 1

Soothill JF, Warner JO (1978). Control Trial of Hyposensitization to Dermatophagoides Pteronyssinus in Children with Asthma. Lancet. 9:912-915.

Boris M, Schiff M, Weindorf S, Insel L (1983). Bronchoprovocation Blocked by Neutralization Therapy (Abstract). 71:92.

Boris MS, Weindorf S, Corriel R, Inselman L, Schiff M (1985). Antigen Induced Asthma Attenuated by Neutralization Therapy. Clinical Ecology. 3:59-62.

Major Books – Asthma (4) 1

Berkley GE. The No Drug Approach to Conquering Asthma and Controlling Emphysema. Larchmont Books, Atlanta, GA. 1986.

Plant T. Children with Asthma; A Manuel for Parents. Pedipress, Amherst, MA. 1984.

Rapp D. Allergies and Your Family. Practical Allergy Research Foundation, P.O. Box 60, Buffalo, NY 14223-0060. 1990.

Young SH, Shulman SA, Shulman MD. The Asthma Handbook: A Complete Guide for Patients and Their Families. Bantam Books, 666 Fifth Avenue, New York, NY 10103. 1985.

Autism Major Studies – Autism (3) 1

O’Banion DB, Armstrong B, Cummings RH (1978). Disruptive Behavior: A Dietary Approach. Journal of Autism and Childhood Schizophrenia. 8:325.

Gaffney GR, Tsai LY, Kuperman S, Minchin S (1987). Cerebellar Structure in Autism. American Journal of Disability in Children. 141:1330-1332.

Volkmar FR, Cohen DJ (1988). Neurobiologic Aspects of Autism. The New England Journal of Medicine. 318:1390-1392.

Major Books – Autism (1) 1

Callahan M. Fighting for Tony. Simon & Schuster, New York, NY. 10020. 1987.

Blood Abnormalities Major Studies – Blood Abnormalities (5) 1

Randolph TG (1944). Differentiation of Leukocytes in Counting Chamber by Propylene Glycol-Aqueous Stains; Screen for Detection of Major Blood Abnormality. American Journal of Clinical Pathology. 8:48.

Mallery Jr OT, Randolph TG (1944). Effect in Vitro of Propylene Glycol on Leukocytes. Journal of Laboratory & Clinical Medicine. 29:203.

Randolph TG, Rawling FFA (1946). Blood Studies in Allergy: V. Variations of Total Leukocytes Following Test Feeding of Foods; An Appraisal of Individual Food Test. Annals of Allergy. 4:163.

Randolph TG (1947). Blood Studies in Allergy: IV. Variations in Eosinophils Following Test Feeding of Foods. Journal of Allergy. 18:199.

Randolph TG, Kroker GF (1978). Allergic Thrombocyteopenia. 12th Advanced Seminar in Clinical Ecology. 103.

Candida Major Books – Candida (8) 1

Connolly P. The Candida Albicans Yeast-Free Cookbook. Keats Publishing, Inc., 27 Pine Street (Box 876), New Canaan, CT 06840. 1985.

Crook W. The Yeast Connection. Professional Books, P.O. Box 3494, Jackson, TN 38301. 1989 (3rd Edition, 18th printing).

Lorenzani SS. Candida: A Twentieth Century Disease. Keats Publishing, Inc., 27 Pine Street (Box 876), New Canaan, CT 06840. 1986.

Remington D, Higa BW. Back to Health. A Comprehensive Medical and Nutritional Yeast Control Program. Vitality House International, Inc., 3707 N. Canyon Rd. #8C, Provo, Utah 84604, (801) 224-9000. 1986.

Rockwell S. Coping with Candida Cook Book. Sally Rockwell, P.O. Box 15181, Seattle, WA 98115. 1984.

Trowbridge JP, Walker DPM. The Yeast Syndrome. Bantam Books, 666 Fifth Avenue, New York, NY 10103. 1986.

Truss CO. The Missing Diagnosis. The Missing Diagnosis, Inc., P.O. Box 26508, Birmingham, AL 35226. 1982.

Wunderlich Jr RC, Kalita DK. Candida Albicans: How to Fight an Exploding Epidemic of Yeast-Related Diseases. Keats Publishing, Inc., 27 Pine Street (Box 876), New Canaan, CT 06840. 1984.

Chemical Sensitivity Major Studies – Chemical Sensitivity (14) 1

Randolph TG (1954). Clinical Sensitivity to Petroleum, Coal, Gas, Pine, and their Derivatives. Journal of Allergy. 25:81.

Randolph TG (1961). Human Ecology and Susceptibility to the Chemical Environment, Parts I & II. Annals of Allergy. 19:518.

Rapp DJ (1972). Water as a Cause of Angio-Edema and Urticaria (Letter to the Editor). The Journal of the American Medical Association. 221,2:305.

Spyker JM (1975). Assessing the Impact of Low Level Chemicals on Development: Behavioral and Latent Effects. Federation Proceedings. 34(9):1835-1844.

Rea W, Bell I, Sutis C, Smiley R (1978). Food and Chemical Susceptibility After Environmental Chemical Overexposure: Case Histories. Annals of Allergy. 41:101110.

6 Knave, et al (1979). Long-Term Exposure to Jet Fuel. Scandanavian Journal Work Environment and Health. 45:19. 7

Rea WJ (1979). Diagnosing Food and Chemical Susceptibility. Education for the Family Physician. 16:47-59.

Radcliffe MJ, et al (1981). Practitioner. 225:1651-1654.

Anderson A (1982). Neurotoxic Follies. Psychology Today. 16:30-33.

Continuing

Food Allergy in Polysymptomatic Patients. The

10 Rotten J, et al (1982). Behavioral Effect of Chemicals in Drinking Water. Journal of Applied Psychology. 67:230-238. 1 1 McGovern J, et al (1983). Otolaryngology. 109:292-297.

Food and Chemical Sensitivity.

Archives of

1 2 Rea WJ (1984). Pesticides and Brain-Function Changes in a Controlled Environment. Clinical Ecology. II(3):145-149. 13 U.S. Government (1986). Neurotoxins at Home and the Workplace. Report from the Committee on Science and Technology. 14 Rea W, Pan Y, Laseter JL, Johnson AR, Fenyves EJ (1987). Toxic Volatile Organic Hydrocarbons in Chemically Sensitive Patients. Clinical Ecology. 2:70. Major Books â&#x20AC;&#x201C; Chemical Sensitivity (1) 1

Mansfield P, Munro J. Chemical Children. Century Hutchinson Ltd., Brookmount House, 62-65 Chandos Place, Covent Garden, London, England WC2N 4NW. 1987.

Colitis Major Studies â&#x20AC;&#x201C; Colitis (2) 1

Soothill JF, Jenkins HR, Pincott JR, Milla PJ, Harris JT (1983). Food Allergy: The Major Cause of Infantile Colitis. Archives of Disease in Childhood. 59:326-329.

McEwan LM (1987). A Double-Blind Controlled Trial of Enzyme Potentiated Hyposensitization for the Treatment of Ulcerative Colitis. Clinical Ecology. 2:47.

Crohn’s Disease Major Studies – Crohn’s Disease (2) 1

Jones A, Dickinson RJ, Workman E (1985). Crohn’s Disease: Maintenance of Remission by Diet. Lancet. ii:177-180.

Paigen B, Rapp DJ. Crohn’s Disease Complicated by Food Allergies: A Case Report of Successful Dietary Management (not accepted for publication).

Delinquency Major Studies – Delinquency (4) 1

Yaryura-Tobias J, Neziroglu F (1975). Violent Behavior, Brain Dysrhythmia and Glucose Dysfunction – A New Syndrome. Orthomolecular Psychiatry. 3:182-188.

Schauss A, et al (1979). A Critical Analysis of the Diets of Chronic Juvenile Offenders. Part 2. Orthomolecular Psychiatry. 4:222-226.

Schmidt K, Weir W, Asch M (1981). Clinical Ecology Treatment Approach for Juvenile Offenders. The Journal of Behavioral Ecology. 2:1.

Schoenthaler SJ (1982). The Effect of Sugar on the Treatment and Control of Antisocial Behavior: A Double-Blind Study of An Incarcerated Juvenile Population. International Journal of Biosocial Research. 3:1-9.

Major Books – Delinquency (2) 1

Schauss A. Diet, Crime, & Delinquency. Parker House, 2340 Parker Street, Berkeley, CA 84704. 1981.

Reed B. Food, Teens, and Behavior. Natural Press, P.O. Box 2107, Manitowoc, WI 54220. 1983.

Diet Major Books – Diet (16)

Callahan M. Fighting for Tony. Simon & Schuster, New York, NY 10020. 1987.

Gerrard, J. Food Allergy, New Perspectives. Springfield, IL. 1980.

Golos N. Coping with Allergies. Simon & Schuster, 130 Avenue of the Americas, New York, NY 10020

Golos N. If This is Tuesday, It Must Be Chicken. Keats Publishing, 27 Pine Street, New Cannan, CT 06840. 1981.

Haga BW. Desserts to Lower Your Fat Thermostat. Vitality House International, 1675 North Freedom Blvd. #11-C, Provo, UT 84604. 1989.

Mandell FG. Dr. Mandell’s Allergy-Free Cookbook. Pocket Books, c/o Simon & Schuster, 1230 Avenue of the Americas, New York, NY 10020. 1981.

Mandell M. Dr. Mandell’s 5-Day Allergy Relief System. Thomas Y. Crowell Publishers, 10 East 53rd Street, New York, NY 10020

Matsen J. Eating Alive; Prevention Through Good Digestion. Crompton Books, Vancouver, B.C.

Mumby K. The Food Allergy Plan. Unwin Publishers, London, England. 1985.

Charles Thomas Publishing,

10 Powell D. Why 5? A Complete Food Allergy Guidebook. B. Sc.N., J.G. MaClennan M.D.. Order from Donna Powe, Box 25, Waterdown, Ontario, Canada, LOR 2HO. 1981. 11 Rasmussen L. Rotation Diet Cookbook. Published by L. Rasmussen Co., Ltd. 12 Remington D, Higa B. The Bitter Truth About Artificial Sweeteners. Vitality House International, 1675 North Freedom Blvd. #11-C, Provo, UT 84604. 1987. 13 Sainsbury IS. The Milk-Free and Milk/Egg-Free Cookbook. Arco Publishing, Inc., New York, NY. 14 Stitt P. Fighting the Food Giants. Natural Press, Manitowoc, WI. 1980. 15 Stone C, Beima J. To Your Health. CC & Co. Publishing, Rolling Meadows, IL. 1988. 16 Weiss L. The Kitchen Magician. Prosperity Publishing.

Drugs Major Studies – Drugs (4) 1

Randolph TG, Rawling FFA (1944). Bronchial Asthma as Manifestation of Sulfonamide Sensitivity. Journal of the American Medical Association. 126:166.

Randolph TG, Rawling FFA (1945). Blood Studies in Allergy: III. Cellular Reactions in Sulfonamide Sensitivity. Journal of Allergy. 16:17.

Randolph TG (1954). Allergic Type Reactions to Synthetic Drugs and Cosmetics. Journal of Laboratory & Clinical Medicine. 44:914.

Randolph TG (1954). Allergic Type Reactions to Chemical Additives of Foods and Drugs. Journal of Laboratory & Clinical Medicine. 44:913.

Eczema Major Studies – Eczema (2) 1

Atherton DJ, Soothill JF, Sewell W, Wells RS (1978). A Double-Blind Controlled Crossover Trial of an Antigen Avoidance Diet in Atopic Eczema. Lancet. 1:401403.

Sampson HA, Broadbent KR, Bernhisel-Bradbent J (1989). Spontaneous Release of Histamine from Basophils and Histamine-Releasing Factor in Patients with Atopic Dermatitis and Food Hypersensitivity. New England Journal of Medicine. 321:228257.

Epilepsy Major Studies – Epilepsy (5) 1

Crayton (1981). Epilepsy Precipitated by Food Sensitivity: Report of a Case with Double-Blind Placebo-Controlled Assessment. Clinical Electroencephalography. 12:192.

Schmidt K, Weir W, Asch M (1981). Clinical Ecology Treatment Approach for Juvenile Offenders. The Journal of Behavioral Ecology. 2:1.

Egger J, Carter CM, Graham PJ, Gumley D, Soothill JF (1985). Controlled Trial of Oligoantigenic Treatment in the Hyperkinetic Syndrome. The Lancet. :540-545.

Egger J, Carter CM, Soothill JF, Wilson J (1989). Oligoantigenic Diet Treatment of Children with Epilepsy and Migraine*. The Journal of Pediatrics. 114 (1):51-58. * The study covered the success of diets free of delayed allergic reactions in 63 children with epilepsy; 45 children had epilepsy with migraine, hyperkinetic behavior, or both, and 18 had epilepsy alone. Of the 45 children who had epilepsy with recurrent headaches, abdominal symptoms, or hyperkinetic behavior, 25 ceased to have seizures and 11 had fewer seizures during diet therapy.

Murphy P (2001). The Role of Sugar in Epileptic Seizures. Townsend Letter for Doctors and Patients. May 2001.

Essential Fatty Acids Major Books – Essential Fatty Acids (2) 1

Berger S. The Immune Power Diet. William Morrow & Co., New York, NY.

Galland L. Super-Immunity for Kids. Copestone Press, New York, NY. 1988.

Fatigue Major Studies – Fatigue (4) 1

Randolph TG, Hettig RA (1945). Coincidence of Allergic Disease, Unexplained Fatigue and Lymphodenopathy; Possible Diagnostic Confusion with Infectious Mononucleosis. American Journal of Medical Science. 209:306.

Randolph TG (1945). Fatigue and Weakness of Allergic Origin (Allergic Toxemia) To Be Differentiated from “Nervous Fatigue” or Neurasthenia. Annals of Allergy. 3:418.

Randolph TG (1947). Allergy as a Causative Factor of Fatigue, Irritability, and Behavior Problems of Children. The Journal of Pediatrics. 31:560-572.

Crook WC, Harrison SE, Crawford BS, Emerson BS (1961). Manifestations Due to Allergy. Pediatrics. 27:790.

Fibromyalgia (originally called ‘Myalgia’)

Systemic

Major Studies – Fibromyalgia (5) 1

Randolph TG (1948). Acute Torticollis Due to Food Allergy. Journal of Laboratory & Clinical Medicine. 33:1614.

Randolph TG (1948). Muscular Symptoms of Allergic Origin. Proc American Federation of Clinical Research. 4:19.

Randolph TG (1949). Allergy as a Cause of Muchal Myalgia and Associated Headache. Arch Otolaryng. 50:745.

Randolph TG (1951). Allergic Myalgia. Journal Mich Med Soc. 50:487.

Randolph TG (1976). Ecologically Oriented Myalgia and Related Musculoskeletal Painful Syndromes. Clinical Ecology. Dickey LD, Ed. Thomas, Springfield, IL. 213.

Food Additives Major Studies – Food Additives (2) 1

Randolph TG (1951). Unlabeled Allergenic Constituents of Commercial Foods and Drugs; Critique of Food, Drug, and Cosmetic Act. Annals of Allergy. 9:151.

Randolph TG (1954). Allergic Type Reactions to Chemical Additives of Foods and Drugs. Journal of Laboratory & Clinical Medicine. 44:913.

Gynecology Major Studies – Gynecology and Obstetrics (5) 1

Miller JB (1974). Relief of Premenstrual Symptoms, Dysmenorrhea, and Contraceptive Tablet Intolerance. The Journal of the Medical Association of Alabama. 44:2.

Mabray CR, Burditt ML, Martin TL, Jaynes CR, Hayes JR (1982). Treatment of Common Gynecologic Endocrinologic Symptoms by Allergy Management Procedures. Obstetrics and Gynecology. 59:560.

Mabray CR (1982). Obstetrics and Gynecology and Clinical Ecology. Part I. Clinical Ecology. 1(1):

Mabray CR (1982). Obstetrics and Gynecology and Clinical Ecology. Part II. Clinical Ecology. 1(2):

Mabray CR (1982). Obstetrics and Gynecology and Clinical Ecology. Clinical Ecology. Gyn 1. (3,4):

Hyperactivity Major Studies â&#x20AC;&#x201C; Hyperactivity (24) 1

Spyker JM (1975). Assessing the Impact of Low Level Chemical on Development: Behavioral and Latent Effects. Federation Proceeding. 34 (9):1835-1844.

Conners CK, Goyette CH, Southwick DA, Lees JM, Andrulonis PA (1976). Food Additives and Hyperkinesis: A Controlled Double-Blind Experiment. Pediatrics. 58:154-166.

Huessy HR, Cohen AH (1976). Hyperkinetic Behaviors and Learning Disabilities Followed Over Seven Years. Journal of Pediatrics. 57:4-10.

Miller JB (1977). A Double-Blind Study of Food Extract Injection Therapy. A Preliminary Report. Annals of Allergy. 38:

Rapp DJ (1978). Food Allergy Treatment for Hyperkinesis. Journal of Learning Disability. 12:79.

Goyette CH, Conners CK, Ulrich RF (1978). Normative Data on Revised Conners Parent and Teacher Rating Scales. Journal of Abnormal Child Psychology. 6:221236.

Rapp DJ (1978). Does Diet Affect Hyperactivity? Journal of Learning Disability. 11:56-62.

Rapp DJ (1978). Double-Blind Confirmation and Treatment of Milk Sensitivity. Medical Journal of Australia. 1:571-572.

Trites R, Tryphonas H, Ferguson B (1979). Chapter: Diet Treatment for Hyperactive Children with Food Allergies. Rehabilitation, Treatment and Management of Learning Disorders. (Knights, RM, Bakker, BJ, eds.). Baltimore: University Park Press.

1 0 Tryphonas H, Trites R (1979). Food Allergy in Children with Hyperactivity, Learning Disabilities and/or Minimal Brain Dysfunction. Annals of Allergy. 42:2227. 1 1 Weiss B (1980). 207:1487-1489.

Behavioral Responses to Artificial Food Colors.

Science.

12 Oâ&#x20AC;&#x2122;Shea JA, Porter SF (1981). Double-Blind Study of Children with Hyperkinetic Syndrome Treated With Multi-Allergen Extract Sublingually. Journal of Learning Disabilities. 14:189. 1 3 Hilson JE (1982). Dietary Control of The Hyperactive Child. Pediatrician. :25-29.

New York

14 Rappaport JL, et al (1982). Chapter: Gilles de la Tourette Syndrome. Hyperkinetic Syndrome and Touretteâ&#x20AC;&#x2122;s Syndrome. (Friedhoff, AJ, Chase, TN, eds.). New York: Raven Press. 15 Gerrard J (1984). Just Food Intolerance. Lancet. 2:413. 16 Egger J, Carter CM, Graham PJ, Gumley D, Soothill JF (1985). Controlled Trial of Oligoantigenic Treatment in The Hyperkinetic Syndrome. Lancet. :540-545. 17 Rapp DJ (1985). Allergies: Are Some Children Pains In The Class? Journal of School Administrators Association of New York. 16:29-32. 18 Hartsough CS, Lambert NM (1985). Medical Factors in Hyperactive and Normal Children: Prenatal, Developmental, and Health History Findings. American Journal of Orthopsychiatry. 55:190. 1 9 Palmer S, Rappaport JL, Quinn PO (1985). Food Additives and Hyperactivity. Clinical Pediatrics. 14:956-959. 2 0 Satterfield J (1987). Therapeutic Interventions to Prevent Delinquency in Hyperactive Boys. Journal of American Academy of Child and Adult Psychology. 26:56-64. 21 Kaplan BJ, McNicol J, Conte RA, Moghadam HK (1987). Sleep Disturbance in Preschool-Aged Hyperactive and Non-Hyperactive Children. Pediatrics. 80:839844. 2 2 Kaplan BJ, McNicol J, Conte RA, Moghadam HK (1987). Physical Signs and Symptoms in Preschool-Aged Hyperactive and Normal Children. Developmental and Behavioral Pediatrics. 8:305-310. 23 Kaplan BJ, McNicol J, Conte RA, Moghadam HK (1989). Dietary Replacement in Preschool-Aged Hyperactive Boys. Pediatrics. 83:7-17. 24 Berdonces JL (2001). Attention Deficit and Infantile Hyperactivity. Rev Enferm. Jan 2001;4(1)11-4.

Major Books – Hyperactivity (5) 1

Crook W. Can Your Child Read, Is He Hyperactive?. 3494, Jackson, TN 38301

O’Banion D. The Ecological and Nutritional Treatment of Health Disorders. C. Thomas Publishers. Bannerstone House, 301-327 E. Lawrence Ave., Springfield, IL.

Rapp DJ. The Impossible Child – In School, At Home. Practical Allergy Research Foundation, P.O. Box 60, Buffalo, NY 14223- 0060

Rapp DJ. Allergies and The Hyperactive Child. Foundation, P.O. Box 60, Buffalo, NY 14223-0060

Sahley BJ. The Natural Way to Control Hyperactivity. The Watercress Press, San Antonio, TX. 1988.

Professional Books, P.O.

Practical Allergy Research

Hypoglycemia Major Books – Hypoglycemia (2) 1

Fredricks C. Carlton Fredricks’ New Low Blood Sugar and You. The Putnam Publishing Group, 200 Madison Avenue, New York, NY 10016. 1985.

Philpott W, Kalita D. Brain Allergies. Keats Publishing Co., 27 Pine Street, New Canaan, CT 06840

Immunology Major Studies – Immunology (14) 1

Sandberg DH, Bernstein CW, McIntosh RM, Carr R, Strauss J (1977). Severe Sterioid-Responsive Nephrosis Associated with Hypersensitivity. Lancet. :388-391.

McGovern JJ (1979). Correlation of Clinical Food Allergy Symptoms Serial with Pharmacological and Immunological Changes in the Patient’s Plasma Study. Annals of Allergy. (Abstract) 44:57.

Rapp DJ (1982). Immunological Studies of Adults with Allergic-Tension-Fatigue Syndrome Due to Sugar (Abstract No. 15). Annals of Allergy. 48:258.

Alun-Jones V, Shorthouse M, McLaughlin P, et al (1982). Food Intolerance: A Major Factor in the Pathogeneses of Irritable Bowel Syndrome. Lancet. ii:115-117.

Alun-Jones A, McLaughlin P, Shorthouse M, Workman E, Hunter JO (1983). Food Intolerance, Prostaglandins and Irritable Bowel Syndrome. Lancet. i:123.

6 McGovern JJ, et al (1983). Otolaryngology. 109:292-297.

Food and Chemical Sensitivity.

Archives of

McGovern JJ, Lazaroni JL, Saifer P, Levin AS, Rapp DJ, Gardner RW (1983). Clinical Evaluation of the Major Plasma and Cellular Measures of Immunity. Orthomolecular Psychiatry. 12:60-71.

Bentley SJ, Pearson Rix KJB, (1983). Food Hypersensitivity in Irritable Bowel Syndrome. Lancet. ii:295-297.

Little CH, Stewart AG, Hennessy MR (1983). Platelet Seratonin Release in Rheumatoid Arthritis: A Study in Food-Intolerant Patients. Lancet. :297.

1 0 Rea WJ (1984). Pesticides and Brain-Function Changes in a Controlled Environment. Clinical Ecology. II (3):145-149. 11 Ting B, Ting S, Maxwell L (1986). Attention Deficit Disorder (ADD) and Food Allergy. Journal of Allergy and Clinical Immunology. 77:208. 12 Scadding GK, Brostoff J (1987). Low Dose Sublingual Therapy in Patients with Allergic Rhinitis Due to House Dust Mite. Clinical Allergy. 16:483-491. 13 Holt PG, Vines J, Britten (1988). Sublingual Allergen Administration. Selective Suppression of IgE Production in Rats by High Allergen Doses. Clinical Allergy. 18:229-234. 14 Sampson HA, Broadbent KR, Bernhisel-Bradbent J (1989). Spontaneous Release of Histamine from Basophils and Histamine-Releasing Factor in Patients with Atopic Dermatitis and Food Hypersensitivity. New England Journal of Medicine. 321:228257.

Insects Major Studies â&#x20AC;&#x201C; Insects (3) 1

Lichtenstein LM, Valentine MD, Sobotka AK (1979). Insect Allergy: The State of the Art. Journal of Allergy and Clinical Immunology. 64:5-12.

Schuberth EC, Lichtenstein LM, Kagey-Sobotka A (1983). Epidemiologic Study of Insect Allergy in Children: Effect of Accidental Stings in Allergic Children. The New England Journal of Medicine. 102:361-365.

Reisman RE, Dvorin DJ, Randolph CC (1985). Stinging Insect Allergy: Natural History and Modification with Venom Immunotherapy. Journal of Allergy and Clinical Immunology. 75:735-740.

Inside Home Major Studies – Inside Home (2) 1

Randolph TG (1954). Allergic Type Reactions to Indoor Utility Gas and Oil Fumes. Journal of Laboratory & Clinical Medicine. 44:913.

Randolph TG (1969). Domiciliary Chemical Air Pollution in the Etiology of Ecologic Mental Illness. Proc 2nd International Congress of Social Psych. Abstract. Avenue, London.

Major Books – Inside Home (10) 1

Dadd DL. The Nontoxic Home. Jeremy P. Tarcher, Inc., Los Angeles, CA.

Department of Consumer Affairs. Clean Your Room! A Compendium on Indoor Pollution. P.O. Box 310, 1020 N. Street, Sacramento, CA 95802

McGee CT. How to Survive Modern Technology. Keats Publishing Co., Box 876, 27 Pine Street, New Canaan, CN 06840

Pfeiffer G, Mikel C. Household Environment & Chronic Illness. Charles Thomas Publishing, Springfield, IL. 1980.

Rousseau D, Rea WJ, Enwright J. Published by Hartley & Marks.

Saifer P. Detox. Ballantine Books, New York, NY

Small B. The Susceptibility Report: Chemical Susceptibility and Unreaformaldehyde Foam Insulation. Small & Associates Publishers, RR #1, Goodwood, Ont. LOC IAO

Tarcher J. Nontoxic & Natural: How to Avoid Dangerous Everyday Products and Buy or Make Safe Ones. Jeremy P. Tarcher, Inc., Los Angeles, CA

Travis N. The Bodywrecker. Don Quixote Publishing Co., P.O. Box 9442, Amarillo, TX 79105

Your Home, Your Health and Wellbeing.

10 Zamm AV. Why Your House May Danger Your Health. F.A.C.A. F.A.C.P. with Robert Gannon. Published by Simon & Schuster.

Irritable Bowel Major Studies – Irritable Bowel (3) 1

Alun-Jones V, Shorthouse M, McLaughlin P, et al (1982). Food Intolerance: A Major Factor in the Pathogeneses of Irritable Bowel Syndrome. Lancet. ii:115-117.

Bentley SJ, Pearson Rix KJB, (1983). Food Hypersensitivity in Irritable Bowel Syndrome. Lancet. ii:295-297.

Alun-Jones A, McLaughlin P, Shorthouse M, Workman E, Hunter JO (1983). Food Intolerance, Prostaglandins and Irritable Bowel Syndrome. Lancet. i:123.

Light Major Studies – Lights (5) 1

Painter M (1975). Fluorescent Lights and Hyperactivity in Children: An Experiment.

Ott J, Mayron EL (1976). Light, Radiation, and Academic Achievement: SecondYear Data. Academic Therapy. 11(4):3997-4007.

Ott J (1985). Color and Light: Their Effects on Plants, Animals and People. International Journal of Biosocial Research. Special Subject Issue 7.

Ott J (1986). Color and Light: Their Effects an Plants, Animals and People. Part 2. International Journal of Biosocial Research. Special Subject Issue 8.

Ott J (1987). Color and Light: Their Effects on Plants, Animals and People. Part 3. International Journal of Biosocial Research. Special Subject Issue 9.

Major Books – Light (2) 1

Ott J. Health and Light. New York: Simon & Schuster Inc.

Ott J, Painter M. Light, Radiation, and You. Greenwich: Devin-Adair. 1975.

Migraine Major Studies – Migraine (9)

Sheldon JM, Randolph TG (1935). Allergy in Migraine-like Headache. American Journal of Medical Science. 190:232.

Randolph TG (1944). Allergic Headache; Unusual Case of Milk Sensitivity. Journal of the American Medical Association. 126:430.

Kailin EW, Hasting A (1970). Electromyographic Evidence of Cerebral Malfunction in Migraine Due to Egg Allergy. Report of a Case. Medical Annals â&#x20AC;&#x201C; District of Columbia 39.

Miller JB (1977). A Double-Blind Study of Food Extract Injection Therapy. A Preliminary Report. Annals of Allergy. 38.

Grant EC (1978). Oral Contraceptives, Smoking, Migraines, and Food Allergy. Lancet. 2:581.

Monro J (1983). Food Allergy and Migraine. Clinical Immunology and Allergy. 42:241-246.

Egger J, Carter CM, Graham PJ, Wilson J, Turner MW, Soothill JF (1983). Is Migraine Food Allergy? A Double-Blind Controlled Trial of Oligoantigenic Diet Treatment. Lancet. II:865-869.

Egger J, Carter CM, Soothill JF, Wilson J (1989). Oligoantigenic Diet Treatment of Children with Epilepsy and Migraine. Journal of Pediatrics. 114(1):51-58.

Miller JB (1987). Chapter: Migraine as a Model Allergic/Stress Disease. Relief at Last! Neutralization for Food Allergy and Other Illnesses. Springfield: Charles C. Thomas.

Nephrosis Major Studies â&#x20AC;&#x201C; Nephrosis (7) 1

Sandberg DH, Bernstein CW, McIntosh RM, Carr R, Strauss J (1977). Severe Steroid-Responsive Nephrosis Associated with Hypersensitivity. Lancet. :388-391.

Kay RA, Ferguson A (1984). Intestinal T Cells, Mucosal Cell-Mediated Immunity and Their Relevance to Food Allergic Disease. Clinical Review of Allergy. 2:55-56.

Howanietz H, Lubac G (1985). Idiopathic Nephrotic Syndrome, Treated with Steroids for Five Years Found To Be Allergic To Pork. Lancet. ii:450.

Lagrue G, Laurent J, Beighiti D, Sainte-Laudy J (1985). Food Sensitivity and Idiopathic Nephrotic Syndrome. Lancet. ii:777.

Genova R, Sanfilippo M, Rossi ME, Vierucci A (1987). Letter to the Editor. Lancet. 6:1315-1316.

Lagrue G, Laurent J, Rostoer G, Lang P (1987). Food Allergy in Idiopathic Nephrotic Syndrome. Lancet. :277.

Sandberg DH (1987). Chapter: Food Sensitivity: The Kidney and Bladder. Food Allergy and Intolerance. (Brostoff, J, Challacombe, J, eds.). London: Bailliere.

Nutrition Major Books â&#x20AC;&#x201C; Nutrition (12) 1

Bland J. Your Personal Health Programme. Thorsons Publishers, Wellingborough, Northamptonshire. 1984.

Kazuhiko A. Miracle Cure Organic Germanium. Biocurrents Press, Division of Nutri-cology Inc., P.O. Box 306, San Leandro, CA 94577. 1980.

Lesser M. Nutrition and Vitamin Therapy. Grove Press, New York, NY 10014. 1980.

Matsen J. Eating Alive: Prevention Through Good Digestion. Published by Crompton Books, Vancouver, B.C.

Mott L, Snyder K. Pesticide Alert: A Guide to Pesticides in Fruits and Vegetables. Club Books, San Francisco. 1987.

Oâ&#x20AC;&#x2122;Banion D. An Ecological and Nutritional Approach to Behavioral Medicine. Charles C. Thomas Publishers. Bannerstone House, 301-327 E. Lawrence Ave., Springfield, IL

Remington D, Higa B. The Bitter Truth About Artificial Sweeteners. Vitality House International, 3707 North Canyon Road #8-C, Prove, Utah 84604. 1987.

Scheinkin D. Food, Mind, & Mood. Warner Books, Inc., 75 Rockefeller Plaza, New York, NY 10019

Vander A. Nutrition, Stress, and Toxic Chemicals. University of Michigan Press. 1981.

10 Wright JV. Healing with Nutrition. Rodale Press.

11 Wright JV. Dr. Wright’s Book of Nutritional Therapy. Rodale Press, Emmaus, PA. 1979. 12 Wunderlich R, Kalita D. Nourishing Your Child. Keats Publishing, New Canaan, CT. 1984.

Obesity Major Studies – Obesity (2) 1

Randolph TG (1947). Masked Food Allergy as Factor in Development and Persistence of Obesity. Journal of Laboratory & Clinical Medicine. 32:1547.

Randolph TG (1964). Food Addiction, Obesity and Alcoholism. International Journal of Social Psychology. Special Edition No. 4, 1st International Congress of Social Psychology. 70.

Otitis Major Studies – Otitis (5) 1

Rapp DJ, Fahey D (1973). (Review Article) Chronic Secretory Otitis and Allergy. Journal of Asthma & Research. 10:193-218.

Shambaugh G (1983). Serous Otitis: Are Tubes The Answer? American Journal of Otology. 5:63-65.

Boris M, Boris G, Weindorf S (1985). Association of Otitis Media With Exposure to Gas Fuels. Clinical Ecology. 4:195-198.

Hagerman RJ, Falkenstein AR (1987). An Association Between Recurrent Otitis Media in Infancy and Later Hyperactivity. Clinical Pediatrics. 253.

Sandberg DH (1987). Chapter: Rhinitis and Secretory Otitis Media: A Possible Role of Food Allergy. Food Allergy and Intolerance. (Brostoff, J, Challacombe, S, eds.). London: Bailliere.

Outside Home Major Studies – Outside Home (3)

Randolph TG (1954). Allergic Type Reactions to Industrial Solvents and Liquid Fuels. Journal of Laboratory & Clinical Medicine. 44:910.

2 Randolph TG (1954). Allergic Type Reactions to Mosquito Abatement Fogs and Mists. Journal of Laboratory & Clinical Medicine. 44:911. 3

Randolph TG (1954). Allergic Type Reactions to Motor Exhausts. Journal of Laboratory & Clinical Medicine. 44:912.

Major Books – Outside Home (4) 1

McGee CT. How to Survive Modern Technology. Keats Publishing Co., Box 876, 27 Pine Street, New Canaan, CT 06840

Stellman J, Daum S. Work is Dangerous to Your Health. Vintage Books, New York, NY.

Makower J. Office Hazards. Tilden Press, Washington, D.C.

Philbrick H, Philbrick J. The Bug Book. Garden Way Publishing, Charlotte, Vermont.

Physical and Psychological Complaints Major Studies – Physical and Psychological Complaints (8) 1

Randolph TG (1950). Allergic Factors in the Etiology of Certain Mental Symptoms. Journal of Laboratory & Clinical Medicine. 36:977.

Randolph TG (1953). Experimentally Induced Cerebral Syndrome Following the Test Feeding of Allergenic Foods. Journal of Laboratory & Clinical Medicine. 42:931.

Randolph TG (1960). Ecologic Mental Illness. Clinical Physiology. 1:23.

Randolph TG (1966). Clinical Ecology As It Affects the Psychiatric Patient. International Journal of Social Psychiatry. 12:245.

Randolph TG (1970). Domiciliary Chemical Air Pollution in the Etiology of Ecologic Mental Illness. International Journal of Social Psychiatry. 16:243.

King DS (1981). Can Allergic Exposure Provoke Psychological Symptoms? A Double-Blind Test. Biological Psychiatry. 16:3-19.

Finn R, Battcock TM (1985). A Critical Study of Clinical Ecology. The Practitioner. 229:883-885.

Crayton JW, Schilling S, McGrath N (1985). The Behavioral Effects of Milk, Wheat, and Chocolate In Food-Sensitive Psychiatric Patients and Controls. Submitted for publication and still not accepted.

Major Books – Physical and Psychological Complaints (2) 1

Randolph TG, Moss RW. An Alternative Approach to Allergies. The New Field of Clinical Ecology Unravels the Environmental Cause of Mental and Physical Ills. Lippincott Publishers, New York, 1980.

Philpott WH, Kalida D. Brain Allergy – The Psychonutrient Connection. Keats Publishers, New Canaan, CT. 1980.

Physician Books Major Books – Physician Books (7) 1

Brostaff J, Challacombe S. Food Allergy and Intolerance. Bailliere Tindall Publisher, London, England. 1987.

Dobbing J. Food Intolerance. Bailliere-Tindall, London, England. 1987.

Lee CH. Allergy Neutralization. Tri Sigma Press, Box 5098, St. Joseph, MO 64505. 1987.

Miller J. Relief at Last! Charles C. Thomas Publishing, 2600 South First St., Springfield, IL 62794-9265. 1987.

Randolph T. Human Ecology and Susceptibility to the Chemical Environment. Charles Thomas Publishing, Springfield, IL. 1962.

Rinkel HJ, Randolph TG, Zeller M. Food Allergy. Charles Thomas Publishing, Springfield, IL 62717. 1951.

Rowe A, Rowe Jr, A. Food Allergy. Charles Thomas Publishers, Springfield, IL 62717. 1972.

Physiological Mechanisms Major Studies – Physiological Mechanisms (2)

Clark HG, Randolph TG (1950). The Acid-Anoxia-Endocrine Theory of Allergy. Journal of Laboratory & Clinical Medicine. 36:811.

Randolph TG (1976). The Enzymatic, Acid, Hypoxia, Endocrine Concept of Allergic Inflammation. Clinical Ecology. Dickey LD, Ed. Thomas, Springfield, IL.

Premenstrual Syndrome Major Studies – Premenstrual Syndrome (1) 1

Miller JB. Chapter: Neutralization Of Menstrual And Premenstrual Syndrome. Relief at Last! Neutralization for Food Allergy and Other Illnesses. Springfield: Charles C. Thomas. 1974.

Prenatal & Infant Major Books – Prenatal & Infant (5) 1

Elvington J. The Poisoned Womb. Penguin, Inc., 40 W. 23rd St., New York, NY 10010. 1985.

MacLennan J. Common Sense for the Sensitive. Human Ecology Foundation of Canada, 465 Highway 8, Dundas, Ontario, L9H 4V9

McNicol J. Baby Beware!!! Published by Alberta Children's Hospital. 1988.

Prompovich C. Feeding Baby Naturally From Pregnancy On. CJ Frompovich Publications, Coopersburg, PA 18036. 1983.

Wunderlich RC. Help for New Parents and Parents-To-Be. Published by Ray C. Wunderlich, Jr. M.D., 666 6th St. S., St. Petersburg, FL 33701-4845. 1989.

Sugar Major Studies – Sugar (107) 1

Cleave TL (1932). A Molecular Conception of Organisms and Neoplasms. Paper.

Couzy F, et al (1933). Nutritional Implications of the Interaction Minerals. Progressive Food and Nutrition Science. 17:65-87.

Randolph TG, Yeager, LB (1949). Corn Sugar as An Allergen. Annals of Allergy. 7:651-661.

Randolph TG, Rollins JP, Walters CK (1949). Allergic Reactions Following Intravenous Injection of Corn Sugar (Dextrose). Journal of Laboratory and Clinical Medicine. 34:1741.

Randolph TG, Rolling JP (1950). Beet Sensitivity: Allergic Reactions From Ingesting Beet Sugar (Sucrose) and Monosodium Glutamate of Beet Origin. Journal of Laboratory and Clinical Medicine. 36:407-415.

Randolph TG, Rollins JP, Walters CK (1950). Allergic Reactions Following Intravenous Injection of Corn Sugar (Dextrose). Archives of Surgery. 61:554-564.

Sandler BP (1951). Diet Prevents Polio. The Lee Foundation for for Nutritional Research, Milwakuee, WI, 1951.

Cleave TL (1956). The Neglect of Natural Priciples in the Current Medical Practice. Journal of the Royal Naval Medical Service. 42:2,55-63.

Randolph TG (1965). Specific Food Constituents of Crystalline Sugars. Trans American Society of Ophthalmology and Otolaryngology. 6:27-37.

10 Scanto S, Yudkin J (1969). The Effect of Dietary Sucrose on Blood Lipids, Serum Insulin, Platelet Adhesiveness and Body Weight in Human Volunteers. Postgraduate Medicine Journal. 45:602-607. 11 Yudkin J (1971). Sugar Consumption and Myocardial Infarction. Lancet. Feb 6, 1971:1(7693):296-297. 1 2 Sanchez A, et al (1973). Role of Sugars in Human Neutrophilic Phagocytosis. American Journal of Clinical Nutrition. 261:1180-1184. 13 Kelsay J, et al (1974). Diets High in Glucose or Sucrose and Young Women. American Journal of Clinical Nutrition. 27:926-936. 1 4 Lemann J (1976). Evidence that Glucose Ingestion Inhibits Net Renal Tubular Reabsorption of Calcium and Magnesium. Journal Of Clinical Nutrition. 70:236245. 15 Ringsdorf W, Cheraskin E, Ramsay R (1976). Sucrose,Neutrophilic Phagocytosis and Resistance to Disease. Dental Survey. 52(12):46-48. 16 Cleave TL (1977). Over-Consumption. Now the Most Dangerous Cause of Disease in the Westernized Countries. Public Health: The Journal of the Society of Community Medicine. 91:3,127-131.

17 Beck-Nielsen H, Pedersen O, Schwartz S (1978). Effects of Diet on the Cellular Insulin Binding and the Insulin Sensitivity in Young Healthy Subjects. Diabetes. 15:289-296. Journal of Clinical Endocrinology and Metabolism. Aug 2000. 1 8 Langseth L, Dowd J (1978). Glucose Tolerance and Hyperkinesis. Cosmetic Toxicology. 16:129-133. 19 Erlander S (1979). The Cause and Cure of Multiple Sclerosis. The Disease to End Disease. Mar 3, 1979;1(3):59-63. 20 Grand E (1979). Food Allergies and Migraine. Lancet. 1:955-959. 21 Gerdes KA, Selner JC (1980). Bronchospasm Following IC Dextrose (Abstract No. 25). Annals of Allergy. :48. 2 2 Prinz RJ, Roberts WA, Hantman E (1980). Dietary Correlates of Hyperactive Behavior In Children. Journal of Consulting and Clinical Psychology. 48:760-769. 23 Yudkin J, Kang S, Bruckdorfer K (1980). Effects of High Dietary Sugar. British Journal of Medicine. Nov 22, 1980;1396. 2 4 Behall K (1982). Influence of Estrogen Content of Oral Contraceptives and Consumption of Sucrose on Blood Parameters. Disease Abstracts International. 1982;431-437. 25 Gardner L, Reiser S (1982). Effects of Dietary Carbohydrate on Fasting Levels of Human Growth Hormone and Cortisol. Proceedings of the Society for Experimental Biology and Medicine. 169:36-40. 26 Rapp DJ (1982). Immunological Studies of Adults With Allergic-Tension-Fatigue Syndrome (ATFS) Due To Sugar. Annals of Allergy. 48:258. 27 Schoenthaler SJ (1982). The Effect of Sugar on The Treatment and Control of Antisocial Behavior: A Double-Blind Study of An Incarcerated Juvenile Population. International Journal of Biosocial Research. 3:1-9. 2 8 Takahashi E (1982). Wholistic Health Digest. Tohoku University School of Medicine. October 1982:41. 29 Fields M, et al (1983). Effect of Copper Deficiency on Metabolism and Mortality in Rats Fed Sucrose or Starch Diets. Journal of Clinical Nutrition. 113:1335-1345. 30 Hodges R, Rebello T (1983). Carbohydrates and Blood Pressure. Annals of Internal Medicine. 98:838-841.

3 1 Thomas BJ, et al (1983). Relation of Habitual Diet to Fasting Plasma Insulin Concentration and the Insulin Response to Oral Glucose. Human Nutrition Clinical Nutrition. 36C(1):49-51. 3 2 Behar D, et al (1984). Sugar Challenge Testing with Children Considered Behaviorally Sugar Reactive. Nutritional Behavior. 1:277-288. 33 Colgan M (1984). Do Nutrient Supplements and Dietary Changes Affect Learning and Emotional Reactions of Children With Learning Difficulties? A Controlled Series of 16 Cases. Nutrition and Health. 3:69-77. 34 Heaton K (1984). The Sweet Road to Gallstones. British Medical Journal. Apr 14, 1984;288:1103-1104. 35 Christensen L, et al (1985). Impact of A Dietary Change on Emotional Distress. Journal of Abnormal Psychology. 94(4):565-579. 36 Rapp DJ (1985). Letter to the Editor Re: Gross Article. Clinical Ecology. 2:106107. Rebuttal in Response to: Gross MD (1984) Effect of Sucrose on Hyperkinetic Children. Pediatrics. 5:876-877. 37 Reiser S (1985). Effects of Dietary Sugars on Metabolic Risk Factors Associated with Heart Disease. Nutritional Health. 203-216. 38 Furukawa CT (1985). Link Questioned Between Sugar “Allergy” and Children’s Behavior. Convention Insights. :1-2. 39 Powers L (1985). Sensitivity: You React to What You Eat. Los Angeles Times. Feb. 12, 1985. 40 Wolraich M, Milich R, Stumbo P, Schultz F (1985). Effects of Sucrose Ingestion On The Behavior of Hyperactive Boys. The Journal of Pediatrics. 106:675-682. 41 Albrink M, Ullrich IH (1986). Interaction of Dietary Sucrose and Fiber on Serum Lipids in Healthy Young Men Fed High Carbohydrate Diets. American Journal of Clinical Nutrition. 43:419-428. 42 Arieff AI (1986). Veterans Administration Medical Center in San Francisco. IVs of sugar water can cut off oxygen to the brain. San Jose Mercury. June 12/86. 43 Darlington L, Ramsey NW, Mansfield JR (1986). Placebo-Controlled, Blind Study of Dietary Manipulation Therapy in Rheumatoid Arthritis. Lancet. Feb1986;8475(1):236-238.

44 Glinsmann W, Irausquin H, Youngmee K (1986). Evaluation of Health Aspects of Sugar Contained in Carbohydrate Sweeteners. FDA Report of Sugars Task Force. 39:36-38. 45 Goldman JA, Lerman RH, Contois JH, Udall JN (1986). Behavioral Effects of Sucrose on Preschool Children. Journal of Abnormal Child Psychology. 14(4):565577. 46 Kozlovsky A, et al (1986). Effects of Diets High in Simple Sugars on Urinary Chromium Losses. Metabolism. 35:515-518. 47 Reiser S, et al (1986). Effects of Sugars on Indices on Glucose Tolerance in Humans. American Journal of Clinical Nutrition. 1986:43;151-159. 48 Taub H, Ed (1986). Sugar Weakens Eyesight. VM Newsletter. May 1986:6 49 Blacklock NJ (1987). Sucrose and Idiopathic Renal Stone. Nutrition and Health. 5(1-2):9-17. 5 0 Cerami A, Vlassara H, Brownlee M (1987). Glucose and Aging. Scientific American. May 1987:90. 51 Yudkin J (1987). Metabolic Changes Induced by Sugar in Relation to Coronary Heart Disease and Diabetes. Nutrition and Health. 5(1-2):5-8. 52 Yudkin J, Eisa O (1988). Dietary Sucrose and Oestradiol Concentration in Young Men. Annals of Nutrition and Metabolism. 32(2):53-55. 53 Keen H, et al (1989). Nutrient Intake, Adiposity, and Diabetes. British Medical Journal. 1:655-658. 54 Furth A, Harding J (1990). Why Sugar Is Bad For You. New Scientist. Sep 23, 1989;44. 55 Lee AT, Cerami A (1990). Modifications of Proteins and Nucleic Acids by Reducing Sugars: Possible Role in Aging. Handbook of the Biology of Aging. New York: Academic Press. 56 Monnier VM (1990). Nonenzymatic Glycosylation, the Maillard Reaction and the Aging Process. Journal of Gerontology 45(4):105-110. 57 Pamplona R, et al (1990). Mechanisms of Glycation in Atherogenesis. Medical Hypotheses. 1990:174-181. 58 Quillin P (1990). Cancer창s Sweet Tooth. Nutrition Science News. Ap2000.

59 Rothkopf M (1990). Nutrition. July/Aug 1990;6(4). 60 Simmons J (1990). Is The Sand of Time Sugar? Longevity. June 1990: 49-53. 61 Christensen L (1991). The Role of Caffeine and Sugar in Depression. Nutrition Report. Mar 1991;9(3):17-24. 62 Goulart FS (1991). Are You Sugar Smart? American Fitness. March-April 1991: 34-38. 63 Kruis W, et al (1991). Effects of Diets Low and High in Refined Sugars on Gut Transit, Bile Acid Metabolism and Bacterial Fermentation. Gut. 32:367-370. 64 The Edell Health Letter. Sept 1991;7:1. 65 Lee AT, Cerami A (1992). The Role of Glycation in Aging. Annals of the New York Academy of Science. 663:63-70. 66 Lechin F, et al (1992). Effects of an Oral Glucose Load on Plasma Neurotransmitters in Humans. Neurophychobiology. 26(1-2):4-11. 67 Nash J (1992). Health Contenders. Essence. Jan 1992;23:79-81. 68 Persson PG, Ahlbom A, Hellers G (1992). Epidemiology. 3:47-52. 69 Sugar, White Flour Withdrawal Produces Chemical Response (1992). The Addiction Letter. Jul 1992:4. 70 Vaccaro O, Ruth KJ, Stamler J (1992). Relationship of Postload Plasma Glucose to Mortality with yr Follow_up. Diabetes Care. Oct 15,1992;10:328-334. 7 1 Dyer DG, et al (1993). Accumulation of Maillard Reaction Products in Skin Collagen in Diabetes and Aging. Journal of Clinical Investigation. 93(6):421-22. 72 Moerman CJ, et al (1993). Dietary Sugar Intake in the Etiology of Biliary Tract Cancer. International Journal of Epidemiology. Ap1993;2(2):207-214. 7 3 Pamplona R, et al (1993). Mechanisms of Glycation in Atherogenesis. Med Hypotheses. 40(3):174-81. 74 Bostick RM, et al (1994). Sugar, Meat. and Fat Intake and Non-dietary Risk Factors for Colon Cancer Incidence in Iowa Women. Cancer Causes & Control. 1994:5:3853. 75 Cornee J, et al (1995). A Case-Control Study of Gastric Cancer and Nutritional Factors in Marseille, France. European Journal of Epidemiology. 1995;11:55-65.

7 6 Jones TW, et al (1995). Enhanced Adrenomedullary Response and Increased Susceptibility to Neuroglygopenia: Mechanisms Underlying the Adverse Effect of Sugar Ingestion in Children. Journal of Pediatrics. Feb 1995;126:171-7. 77 Donnini D, et al (1996). Glucose May Induce Cell Death through a Free Radicalmediated Mechanism. Biochem Biohhys Res Commun. Feb 15, 1996:219(2):412417. 78 Hellenbrand W (1996). Diet and Parkinson's Disease. A Possible Role for the Past Intake of Specific Nutrients. Results from a Self-administered Food-frequency Questionnaire in a Case-control Study. Neurology. Sep 1996;47(3):644-650. 7 9 Lewis GF, Steiner G (1996). Acute Effects of Insulin in the Control of Vldl Production in Humans. Implications for Theinsulin-resistant State. Diabetes Care. 1996 Apr;19(4):390-3. 80 Suadicani P, et al (1996). Adverse Effects of Risk of Ishaemic Heart Disease of Adding Sugar to Hot Beverages in Hypertensives Using Diuretics. Blood Pressure. Mar 1996;5(2):91-71. 81 Bernstein J, et al (1997). Depression of Lymphocyte Transformation Following Oral Glucose Ingestion. American Journal of Clinical Nutrition. 30:613. 82 Lenders CM (1997). Gestational Age and Infant Size at Birth Are Associated with Dietary Intake among Pregnant Adolescents. Journal of Nutrition. Jun 1997;11131117. 83 Curhan G, et al (1998). Beverage Use and Risk for Kidney Stones in Women. Annals of Internal Medicine. 28:534-340. 84 De Stefani E (1998). Dietary Sugar and Lung Cancer: A Case-Control Study in Uruguay. Nutrition and Cancer. 31(2):132-137. 85 Fields M (1998). Journal of the American College of Nutrition. Aug 1998;17(4):317321. 86 Lenders CM (1998). Gestational Age and Infant Size at Birth Are Associated with Dietary Intake Among Pregnant Adolescents. Journal of Nutrition. 128 (1998):1807-1810. 87 Makinen KK, et al (1998). A Descriptive Report of the Effects of a 16-month Xylitol Chewing Gum Programme Subsequent to a 40-month Sucrose Gum Programme. Caries Research. 32(2)107-112.

88 Tj_derhane L, Larmas M (1998). A High Sucrose Diet Decreases the Mechanical Strength of Bones in Growing Rats. Journal of Nutrition. 128:1807-1810. 8 9 Gluconeogenesis in Very Low Birth Weight Infants Receiving Total Parenteral Nutrition. Diabetes. 1999 Apr;48(4):791-800. 90 Ludwig DS, et al (1999). High Glycemic Index Foods, Overeating, And Obesity. Pediatrics. Mar 1999;103(3):26-32. 91 Misciagna G, et al (1999). American Journal of Clinical Nutrition. 69:120-126. 92 Sunehag AL, et al (1999). Gluconeogenesis in Very Low Birth Weight Infants Receiving Total Parenteral Nutrition. Diabetes. 48:7991-800. 9 3 Tominaga M, et al (1999). Impaired Glucose Tolerance Is a Risk Factor for Cardiovascular Disease, But Not Fasting Glucose. Diabetes Care. 1999:2(6):920924. 94 Ceriello A (2000). Oxidative Stress and Glycemic Regulation. Metabolism. Feb 2000;49(2 Suppl 1):27-29. 9 5 Stern N, Tuck M (2000). Pathogenesis of Hypertension in Diabetes Mellitus. Diabetes Mellitus, a Fundamental and Clinical Test. 2nd Edition, 943-957. 96 Annual Meeting of the American Psychological Society, Toronto, June 17, 2001. 97 Berdonces JL (2001). Attention Deficit and Infantile Hyperactivity. Rev Enferm. Jan 2001;4(1)11-4. 98 Christansen D (2001). Critical Care: Sugar Limit Saves Lives. Science News. June 30, 2001; 159:404. 99 Frey J (2001). Is There Sugar in the Alzheimer창s Disease? Annales De Biologie Clinique. 59(3):253-257. 100Murphy P (2001). The Role of Sugar in Epileptic Seizures. Townsend Letter for Doctors and Patients. May 2001. 101Acta Ophthalmologica Scandinavica (2002). March 2002;48;25. 102Cheng J, et al (2002). Preliminary Clinical Study on the Correlation Between Allergic Rhinitis and Food Factors. Lin Chuang Er Bi Yan Hou Ke Za Zhi. Aug 2002;16(8):393-396. 103Colantuoni C, et al (2002). Evidence That Intermittent, Excessive Sugar Intake Causes Endogenous Opioid Dependence. Obes Res. Jun 2002;10(6):478-488.

104Michaud D (2002). Dietary Sugar, Glycemic Load, and Pancreatic Cancer Risk in a Prospective Study. J Natl Cancer Inst. Sep 4, 2002;94(17):1293-1300. 105Molteni R, et al (2002). A High-Fat, Refined Sugar Diet Reduces Hippocampal Brain-derived Neurotrophic Factor, Neuronal Plasticity, and Learning. NeuroScience. 112(4):803-814. 106Veromann S, et al (2003). Dietary Sugar and Salt Represent Real Risk Factors for Cataract Development. Ophthalmologica. 2003 Jul-Aug;217(4):302-307. 107Schoenthaler S. The Los Angeles Probation Department Diet-Behavior Program: Am Empirical Analysis of Six Institutional Settings. Int J Biosocial Res. 5(2):88-89. Major Books – Sugar (7) 1

Appleton N. Healthy Bones. Avery Penguin Putnam, New York, 1989.

Appleton N. Lick the Sugar Habit. Deluxe Paperback.

Cleave T, Campbell G. Diabetes, Coronary Thrombosis and the Saccharine Disease. John Wright and Sons, Bristol, England, 1960.

Cleave TL. Saccharine Disease: Publishing, 1975.

Crook WJ. The Yeast Connection. Professional Books, TN, 1984.

Dufty WF. Sugar Blues. Mass Market Paperback.

Schauss A. Diet, Crime and Delinquency. Parker House, Berkley, CA, 1981.

The Master Disease of Our Time.

Keats

Tourette’s Syndrome Major Studies – Tourette’s Syndrome (2) 1

Rapp DJ (1986). Letter to the Editor Re: Allergy and Tourette’s Syndrome. Annals of Allergy. 56:507.

Comings DE, Comings BG (1987). A Series of Published Articles on Tourette Syndrome. American Journal of Human Genetics. 41:701-741.

Major Books – Tourette’s Syndrome (1) 1

Rappaport JL, et al. Hyperkinetic Syndrome and Tourette’s Syndrome. Gilles de la Tourette Syndrome. (Friedhoff, AJ, Chase, TN, eds.). New York: Raven Press. 1982

Vitamin C Major Books – Vitamin C (2) 1

Pauling L. How to Live Longer and Feel Better. Avon Books, 1790 Broadway, New York, NY 10019. 1986.

Cameron E, Pauling L. Cancer and Vitamin C. Linus Pauling Institute of Science and Medicine, Menlo Park, CA 94025. 1979.

Miscellaneous Major Studies – Miscellaneous (6) 1

Randolph TG (1964). Allergic Symptoms After Viral Infections. Journal of the American Medical Association. 189:174.

Randolph TG (1974). Restless Legs – Brainfag Syndrome. Clinical Research. 22:644A.

Fries JH (1978). Chocolate: A Review. Annals of Allergy. 41: 204.

Radcliffe MJ, et al (1981). Food Allergy In Polysymptomatic Patients. The Practitioner. 225:1651-1654.

Romanski B (1987). The Problem of Allergic Diseases In Poland. Presentation. Fifth International Paul Ehrlich Seminar.

Davis ES (1988). Ecological Illness Gaining Ground at Social Security Administration. The Human Ecologist. 39:20-21.

Major Studies – Unpublished Miscellaneous (6) 1

McGovern J, Bastien S. Validity of Provocative Challenge Test In Diagnosis of Adverse Reactions to Phenol. Berkeley, CA.

Crayton J, Schilling S. Behavioral and Immunological Reactions to Wheat, Milk and Chocolate In Food-Sensitive Psychiatric Patients and Controls. Department of Psychiatry, University of Chicago.

McGovern J, et al. Immunologic Diagnosis of Adverse Reactions To Food and Petrochemicals. Submitted to Lancet.

Rapp DJ, McGovern J. Immunologic Diagnosis and Treatment of Hyperkinesis In Childhood. Submitted to Lancet.

Paigen B, Rapp DJ. Crohnâ&#x20AC;&#x2122;s Disease Complicated By Food Allergies: A Case Report of Successful Dietary Management.

Rapp DJ. Hyperactivity and Food Sensitivity. Submitted to International Pediatrics; refused.

British Books Major British Books (11) 1

Brostoff J, Challocombe SJ. Food Allergy and Intolerance. Bailliere Tindall Publisher, London. 1987.

Dobbing J. Food Intolerance. Bailliere Tindall, London. 1987.

MacKarness R. Not All In The Mind. Pan Books Ltd., Cavaye Place, London, England SWIO 9PG

Hill AN. Against the Unsuspected Enemy. Horizon, Horizon House, 5 Victoria Drive, Bognor Regis, West Sussex, England P021 RH

Lewith G, Kenyon J. Clinical Ecology: The Treatment of Ill Health Caused By Environmental Factors. Thorson Publishers Ltd., Wellingborough, Northamptonshire.

Mansfield P, Munro J. Chemical Children. Century Publishing, London, England.

Rippere V. The Allergy Problem. Northamptonshire.

MacKarness R. Chemical Victims. Pan Books, London. 1980.

Franklin AJ. The Recognition and Management of Food Allergy in Children. Parthenon Publishing Group, 120 Mill Road, Park Ridge, NJ. 1988.

Thorsons Publishers, Wellingborough,

10 Kingsley P. Conquering Cystitis. Ebury Press, London. 1987. 11 Mumby K. The Food Allergy Plan. Unwin Publishers, London. 1985.

Positive Double-Blind Studies Major Positive Single-Blind Diet Studies (7) 1

Randolph TG, Rollins JP (1950). Beet Sensitivity: Allergic Reactions From Ingesting Beet Sugar (Sucrose) and Monosodium Glutamate of Beet Origin. Journal of Laboratory and Clinical Medicine. 366:407-415.

Randolph TG, Rollins JP, Walter CK (1950). Allergic Reactions From Ingestion or Intravenous Injection of Cane Sugar (Sucrose). Journal of Laboratory and Clinical Medicine. 36:242-248.

Randolph TG, Tollins JP, Walter CK (1950). Allergic Reactions Following Intravenous Injection of Corn Sugar (Dextrose). Archives of Surgery. 61:554-564.

Crook WC, Harrison SE, Crawford BS, Emerson BS (1961). Manifestations Due To Allergy. Pediatrics. 27:790.

Green M (1974). Sublingual Provocative Testing For Foods and F, D & C Dyes. Annals of Allergy. 33:274-281.

Finn R, Cohen HN (1978). Food Allergy: Fact Or Fiction. Lancet. 1:426-428.

Oâ&#x20AC;&#x2122;Banion BR, Armstrong B, Cummings RH (1978). Disruptive Behavior: A Dietary Approach. Journal of Autism and Childhood Schizophrenia. 8:325.

Systemic

Major Positive Double-Blind Diet Studies (27) 1

Atherton DJ, Soothill JF, Sewell W, Wells RS (1978). A Double-Blind Controlled Crossover Trail of An Antigen Avoidance Diet In Atopic Eczema. Lancet. 1:401103.

Levy F, Dumbrell S, Hobbes M, Ryan M, Wilton N, Woodhill JM (1978). Hyperkinesis and Diet: A Double-Blind Crossover Trial With a Tartrazene Challenge. The Medical Journal of Australia. 1:61-64.

Williams JI, Cram DM, Tausig FT, Webster E (1978). Relative Effects of Drugs and Diet on Hyperactive Behaviors: An Experimental Study. Pediatrics. 61:811-817.

Rapp DJ (1978). Does Diet Affect Hyperactivity? Journal of Learning Disabilities. 11:56-62.

Rapp DJ (1978) Weeping Eyes In Wheat Allergy. Trans-American Society of Ophthalmology and Otolaryngology. 18:149.

Shaywitz BA, Goldenring JR, Wool RS (1978). Effects of Chronic Administration of Food Colorings on Activity Levels and Cognitive Performance In Normal and Hyperactive Developing Rat Pups. Annals of Neurology. 4:196.

Tryphonas H, Trites R (1979). Food Allergy In Children With Hyperactivity, Learning Disabilities and/or Minimal Brain Dysfunction. Annals of Allergy. 42:2227.

Gerdes KA, Selner JC (1980). Bronchospasm Following IV Dextrose (Abstract No. 25). Annals of Allergy: 48.

Weiss B (1980). 207:1487-1489.

Behavioral Responses to Artificial Food Colors.

Science.

10 Swanson J (1980). Food Dyes Impair Performance of Hyperactive Children on a Laboratory Learning Test. Science. 207:1485-1487. 1 1 Prinz RJ, Roberts WA, Hantman E (1980). Dietary Correlates of Hyperactive Behavior In Children. Journal of Consulting and Clinical Psychology. 48:760-769. 12 Crayton (1981). Epilepsy Precipitated By Food Sensitivity: Reprot of a Case With Double-Blind Placebo-Controlled Assessment. Clinical Electroencephalography. 12:192. 13 Radcliffe MJ (1981). Food Allergy In Polysymptomatic Patients. The Practitioner. 225:1651-1654. (British) 14 Rapp DJ (1981). A Prototype For Food Sensitivity Studies In Children (Abstract No. 25). Annals of Allergy. 47:123-124. 1 5 Bernstein M (1982). Double-Blind Food Challenge In The Diagnosis Of Food Sensitivity In The Adult. Journal of Allergy and Clinical Immunology. 70:205-210. 16 Soothill JF, Jenkins HR, Pincott JR, Milla PJ, Harris JT (1983). Food Allergy: The Major Cause of Infantile Colitis. Archives of Disease in Childhood. 59:326-329. 17 Monro J (1983). Food Allergy and Migraine. Clinical Immunology and Allergy. 42:241-246.

18 Egger J, Carter CM, Wilson J, Turner MW, Soothill JF (1983). Is Migraine Food Allergy? A Double-Blind Controlled Trial of Oligoantigenic Diet Treatment. Lancet. 11:865-869. 19 Gerrard J (1984). Just Food Intolerance. Lancet. 2:413. 20 Colgan M, Colgan L (1984). Do Nutrient Supplements and Dietary Changes Affect Learning and Emotional Reactions of Children With Learning Difficulties? A Controlled Series Of 16 Cases. Nutrition and Health. 3:69-77. 21 Egger J, Carter CM, Graham PJ, Gumley D, Soothill JF (1985). Controlled Trial of Oligoantigenic Treatment In The Hyperkinetic Syndrome. Lancet. :540-545. 22 Finn R, Battcock TM (1985). A Critical Study of Clinical Ecology. The Practitioner. 229:883-885. (British) 2 3 Lagrue G, Laurent J, Beighiti D, Sainte-Laudy J (1985). Food Sensitivity and Idiopathic Nephrotic Syndrome. Lancet. ii:777. 24 Goldman JA, Lerman RH, Contois JH, Udall JR (1986). Behavioral Effects of Sucrose On Preschool Children. Journal of Abnormal Child Psychology. 14 (4):585587. 25 Egger J, Carter CM, Soothill JF, Wilson J (1989). Oligoantigenic Diet Treatment of Children With Epilepsy and Migraine. Journal of Pediatrics. 114 (1):51-58. 26 Kaplan BJ, McNicol J, Conte RA, Moghadam HK (1989). Dietary Replacement In Preschool-Aged Hyperactive Boys. Pediatrics. 83:7-17. 27 Trites RW, Tryphonas H, Ferguson B. Case Studies in Treatment of Hyperactivity in a Child with Allergies to Food. Springfield, IL: Charles C. Thomas. Major Positive Key Non-Blind Diet Studies (10) 1

Shofield AT (1908). A Case of Egg Poisoning. Lancet. 1:716.

Schloss OM (1912). A Case of Allergy to Common Foods. American Journal of Disabled Children. 111:341.

Keston BM, Waters I, Hopkins JG (1935). Oral Desensitization to Common Foods. Journal of Allergy. 6:431-436.

Black JH (1942) . The Treatment of Food Allergy. Southern Medical Journal. 25:771-773.

Vaughan WT, Black JH (1954). Practice of Allergy. St. Louis: CV March Co :321323.

6 Sandberg DH, Bernstein CW, McIntosh RM, Carr R, Strauss J (1977). Severe Steroid-Responsive Nephrosis Associated With Hypersensitivity. Lancet. :388-391. 7

Buisseret PD (1978). Common Manifestations of Cowâ&#x20AC;&#x2122;s Mild allergy In Children. Lancet. 1:304.

Rapp DJ (1978). Does Diet Affect Hyperactivity? Journal of Learning Disabilities. 11:56-62.

Hunter B (1983-84). Some Food Allergies as Neuroexcitors and Neurotoxins. Clinical Ecology. 11 (2):83-89.

10 Ting B, Ting S, Maxwell L (1986). Attention Deficit Disorder (ADD) and Food Allergy. Journal of Allergy and Clinical Immunology. 77:208. Negative Double-Blind Diet Studies (10) 1

Breneman JC, Cook WC, Deamer W, Exline L, Gerrard KW, Heiner D, Hurst A, Leney FL (1973). Report of The Food Allergy Committee on The Sublingual Method of Provocative Testing for Food Allergy. Annals of Allergy. 31:382.

Breneman JC, Cook WC, Deamer W, Exline L, Gerrard KW, Heiner D, Hurst A, Leney FL (1974). Final Report of The Food Allergy Committee on Clinical Evaluation of Sublingual Provocative Testing Method for Diagnosis of Food Allergy. Annals of Allergy. 33:164.

Weiss B (1982). Color Me Hyperactive. American Health. :68-73. Critique of Conners, et al Study: Conners CK, Goyette CH, Southwick DA, Lees JM, Andrulonia PA (1976). Food Additives and Hyperkinesis: A Controlled DoubleBlind Experiment. Pediatrics. 58:154-166.

Rippere V (1983). Food Additives And Hyperactive Children: A Critique of Conners. British Journal of Clinical Psychology. 22:19-32. Critique of Conners et al Study: Conners CK, Goyette CH, Southwick DA, Lees JM, Andrulonia PA (1976). Food Additives and Hyperkinesis: A Controlled Double-Blind Experiment. Pediatrics. 58:154-166.

Harley JP, Ray RS, Tomasi L, Eichman PL, Matthews CG, Chun R, Cleeland CS, Traisman E (1978). Hyperkinesis and Food Additives: Testing The Feingold Hypothesis. Pediatrics. 61:818-828.

Harley JP, Matthews CG, Eichman MD (1978). Synthetic Food Colors and Hyperactivity In Children: A Double-Blind Challenge Experiment. Pediatrics. 62:975-983.

Rapp DJ (1985). Letter To The Editor Re: Gross Article. Clinical Ecology. 2:106107. Critique of Gross Article: Gross MD (1984). Effect of Sucrose on Hyperkinetic Children. Pediatrics. 74:876-878.

Furukawa CT (1985). Link Questioned Between Sugar “Allergy” and Children’s Behavior. Convention Insights. :1-2.

Woolraich M, Milich R, Stumbo P, Schultz F (1985). Effects of Sucrose Ingestion on the Behavior of Hyperactive Boys. Journal of Pediatrics. 106:675-682.

10 Jewett DL, Greenburg (1985). Placebo Response In Intradermal Provocation Testing With Food Extracts (Abstract No. 401). Journal of Allergy and Immunology. 75:205. Major Positive Double-Blind Sublingual Studies Provocative/Neutralization Testing (13) 1

Rapp DJ (1972). Water as a Cause of Angio-Edema and Urticaria. Letter to the Editor. Journal of the American Medical Association. 221 (3):305.

Rapp DJ (1978). Weeping Eyes In Wheat Allergy. Trans-American Society of Ophthalmalogy and Otolaryngology. 18:149.

Rapp DJ (1978). Double-Blind Confirmation and Treatment of Milk Sensitivity. Medical Journal of Australia. 1:571-572.

Rapp DJ (1978). Food Allergy Treatment for Hyperkinesis. Journal of Learning Disability. 12:79.

King DS (1981). Can Allergic Exposure Provoke Psychological Symptoms? A Double-Blind Test. Biological Psychiatry. 16:3-19.

Rapp DJ (1981). A Prototype For Food Sensitivity Studies In Children (Abstract No. 25). Annals of Allergy. 47:123-124.

O’Shea JA, Porter SF (1981). Double-Blind Study of Children With Hyperkinetic Syndrome Treated With Multi-Allergen Extract Sublingually. Journal of Learning Disabilities. 14:189.

Mandell M, Conte A (1982). The Role of Allergy In Arthritis, Rheumatism, and Polysymptomatic Cerebral, Visceral, and Somatic Disorders: Double-Blind Study. Journal of International Academy of Preventive Medicine.

Monro J (1983). Food Allergy and Migraine. Clinical Immunology and Allergy. 42:241-246.

10 Brostoff J, Scadding GI (1986). Low Dose Sublingual Therapy In Patients With Allergic Rhinitis Due To House Dust Mite. Clinical Allergy. 16:483-491. (British) 11 Brostoff J, Scadding G (1988). Study: Double-Blind Sublingual Treatment and Immunological Studies. Department of Immunology, Middlesex Hospital, London, England (Abstract – Dallas Meeting). 12 King WP, Rubin WA, Fadal RG, Ward WA, Trevino RJ, Pierce WB, Stewart JA, Boyles JH (1988). Provocation-Neutralization: A Two-Part Study. Part 1. The Intracutaneous Provocative Food Test: A Multi-Center Comparison Study. Otolaryngology – Head and Neck Surgery. 99:263-277. 13 Rapp DJ (1986). Chapter: Sublingual Testing and Treatment. Food Allergy and Intolerance. (Brostoff, J, Challacombe, S, eds.). Philadelphia: Bailliere Tindall – W.B. Saunders. Negative Sublingual Provocation/Neutralization Studies (3) 1

Breneman JC, et al (1974). Final Report of The Food Allergy Committee of ACA On Clinical Evaluation of Sublingual Provocative Testing Method For Diagnosis of Food Allergy. Annals of Allergy. 33:164.

Lehman CW (1980). A Double-Blind Study of Sublingual Provocative Food Testing: A Study of Efficacy. Annals of Allergy. 45:144.

Major Positive Double-Blind Studies Provocation/Neutralization, Subcutaneous Treatment (10) 1

Miller JB (1977). A Double-Blind Study of Food Extract Injection Therapy: A Preliminary Report. Annals of Allergy. 38:

Rapp DJ (1978). Possible New Way To Treat Herpes Progenitalis. Letter to the Editor (Abstract No. 61). NYS Journal of Medicine. 78:

Rapp DJ (1979). Food Allergy Treatment For Hyperkinesis. Journal of Learning Disabilities. 12:42-50.

Rapp DJ (1981). A Prototype For Food Sensitivity Studies In Children (Abstract No. 25). Annals of Allergy. 47:123-124.

Bentley SJ, Pearson DJ, Rix KB (1983). Food Sensitivity Studies In Irritable Bowel Syndrome. Lancet. ii:295-297.

Boris M, Schiff M, Weindorf S, Inselman L (1983). Bronchoprovocation Blocked By Neutralization Therapy (Abstract). 71:92.

Rea WJ, Podell RN, Williams M, Fenyves I, Sprague DE, Johnson AR (1984). Elimination of Oral Food Challenge Reaction By Injection of Food Extracts. Archives of Otolaryngology. 110:

Finn R, Battcock TM (1985). A Critical Study of Clinical Ecology. The Practitioner. 229:883-885.

Boris M, Weindorf S, Corriel R, Inselman L, Shiff M (1985). Antigen Induced Asthma Attenuated By Neutralization Therapy. Clinical Ecology. 3:59-62.

10 Gerrard JW, King DS (1989). A Double-Blind Study On The Value of Low-Dose Immunotherapy In The Treatment of Asthma and Allergic Rhinitis. Clinical Ecology. 6:43-46. Negative Studies of Provocation or Subcutaneous Food Testing (3) 1

Bronsky EA, Burley DP, Ellis EF (1971). Evaluation of The Provocative Food Skin Test Technique (Abstract). Journal of Allergy. 47:104.

Draper WL (1972). Food Testing In Allergy: Intradermal Provocation Versus Deliberate Feeding. Archives of Otolaryngology. 95:169.

Crawford LV, et al (1976). A Double-Blind Study of Subcutaneous Food Testing Sponsored By The Food Committee of The American Academy of Allergy. Journal of Allergy and Clinical Immunology. 57:236.

Major Double-Blind Oral (P.O.) Studies (4) 1

Taudorf E, Laursen LC, Lanner A, Bjorksten B, Dreborg S, Soborg M, Weeke B (1987). Oral Immunotherapy In Birch Pollen Hay Fever. (Denmark and Sweden). Journal of Allergy and Clinical Immunology. 80:153-161.

Sjovall P, Christensen O, Moller H (1987). Oral Hyposensitization In Nickel Allergy. Journal of American Academy of Dermatology. 17:774-778.

Holt PG, Vines J, Britten D (1987). Sublingual Allergen Administration. I. Selective Suppression of IgE Production In Rats By High Allergen Doses. Clinical Allergy.

Van Niekerk CH, De Wet JI ( 1987). Efficacy of Grass-Maize Pollen Oral Immunotherapy In Patients With Seasonal Hay-Fever: A Double-Blind Study. Clinical Allergy. 17:507-513.

Negative Review Articles (8) 1

Gilbert TM (1975). A Review of Controversial Diagnostic and Therapeutic Techniques Employed In Allergy. Journal of Allergy and Clinical Immunology. 56:170-190.

Grieco MH (1982). Controversial Practices In Allergy. Journal of the American Medical Association. 247:3106-3111.

Van Metre TE (1983). Critique Of Controversial And Unproven Procedures For Diagnosis And Therapy Of Allergic Disorders. Pediatric Clinics of North America. 30:807-817.

Jarvis WT (1983). Food Faddism, Cultism, and Quackery. Annual Review of Nutrition. 3:35-52.

West J (1986). California Medical Association Science Board Task Force On Clinical Ecology: Clinical Ecology – A Critical Appraisal (Information). Clinical Ecology. 144:239-245.

Terr AI (1986). Environmental Illness. A Clinical Review of 50 Cases. Archives of Internal Medicine. :146.

Ellis E (1986). Clinical Ecology: Myth And Reality. Buffalo Physician. 5:17-28.

Barrett S (1989). Unproven “Allergies”: An Epidemic Of Nonsense. Nutrition Today. 3:6-11.

Major Rebuttal Article (1) 1

Rapp DJ (1988). Letter to the Editor Re: Council Report – In Vivo Diagnostic Testing. Journal of the American Medical Association. 260:342. In Response to:

Council On Scientific Affairs (1987). In Vivo Diagnostic Testing and Immunotherapy For Allergy. Report I, Part I Of The Allergy Panel. Journal of the American Medical Association. 258:1363-1367. Council On Scientific Affairs (1987). In Vivo Diagnostic Testing and Immunotherapy For Allergy. Report I, Part II Of The Allergy Panel. Journal of the American Medical Association. 258:1505-1509. Council On Scientific Affairs (1987). In Vivo Diagnostic Testing and Immunotherapy For Allergy. Report II Of The Allergy Panel. Journal of the American Medical Association. 258:1639-1643. Negative Position Papers (7) 1

Reisman R (1981). American Academy of Allergy: Position Statements, Controversial Techniques. Journal of Allergy and Clinical Immunology. 67:333-338.

Council on Scientific Affairs (1987). In Vivo Diagnostic Testing and Immunotherapy For Allergy. Report I, Part I Of The Allergy Panel. Journal of the American Medical Association. 258:1363-1367.

Council On Scientific Affairs (1987). In Vivo Diagnostic Testing and Immunotherapy For Allergy. Report I, Part II Of The Allergy Panel. Journal of the American Medical Association. 258:1505-1509.

Council On Scientific Affairs (1987). In Vivo Diagnostic Testing and Immunotherapy For Allergy. Report II Of The Allergy Panel. Journal of the American Medical Association. 258:1639-1643.

Shapiro, Anderson (1989). Position Paper, Controversy in Techniques in Allergy. Pediatrics. 82(6):935.

Terr AI (1989). Position Paper on Clinical Ecology. Annals of Internal Medicine. III (2):168-178.

Kailin EW, Collier R (1971). Relieving Therapy For Antigen Exposure. Letter to the Editor. Journal of the American Medical Association. 217 (1):78.

Major Positive Studies on Rinkel Method (1) 1

Kniker WT (1982). Aggressive Coseasonal Immunotherapy In Mountain Cedar Pollen Allergy. Archives of Otolaryngology.

Negative Studies on Rinkel Method (1) 1

Hirsch SR, et al (1981). Rinkel Injection Therapy: A Multi Center Controlled Study. Journal of Allergy and Clinical Immunology. 68:133.