Thursday, September 12, 2013

Page 1

w w w .w e sterngazette .c a • @uw ogaze tt e

Beating the Books Students start textbook buyback service >> pg. 3

thegazette Dodging tornadoes since 1906

Thursday, September 12, 2013

today high 22 low 13

tomorrow high 15 low 7

canada’s only Daily Student Newspaper • founded 1906

Volume 107, issue 6

Brain pathway uncovered Students look to Discovery could help treat opiate addiction

say ‘see ya’ to CFS Aaron Zaltzman Associate Editor

Logan Ly Gazette

Megan Devlin News Editor Western researchers have uncovered how memory-forming biochemical pathways in the brain change with chronic opiate use in addicts. The research, led by Steven Lavoilette of the Schulich School of Medicine and Dentistry, may have applications in the treatment of addiction. “The most exciting part of this research is uncovering the fact that there’s a different mechanism for how memories are controlled in the addicted state and in the non-addicted state,” Laura Rosen, a graduate student on the research team, said. “People who haven’t had any exposure to drugs will process these potent drug memories using different molecules than those who are already addicted,” Rosen continued. The potent, euphoric memories formed when using opiate drugs are processed by the basal amygdala. In the rat model used by the researchers, it was found that the chemical mechanism used when recording these memories switched when rats were opiate-dependent. When non-dependent rats were

Varsity Housing - 75 Ann Street Skyline Apartments - 1223 Richmond St.

exposed to heroin they formed their drug-induced memories using a molecule called extracellular signal-related kinase (ERK). However, when rats addicted to the opiate were exposed to heroin, they formed their memories using a different chemical pathway that involved calmodulin dependent kinase II (CaMII). “It’s a fundamental change in brain signaling between people who are not addicted and those who are,” Rosen said. Rosen explained these molecules are involved in memory and learning and are usually present in the brain, but it is not known currently why or after how long the switch from ERK to CaMII occurs in opiate users. “Hopefully [this research] brings to light that [drug users] actually have molecular and cellular changes going on in their brains which control their behavior and it’s not necessarily criminal negligence or some sort of upbringing that drives these people to drugs,” Jordan Zunder, another graduate student on the research team, said. The researchers speculated that with the new knowledge of

these memory-forming pathways, new pharmaceuticals could be developed to help treat addiction. Perhaps by blocking part of these memory-forming pathways, an opiate-dependent person would be less likely to go back to drug use. “I think it’s an incredibly useful piece of the puzzle around helping to treat people with addiction issues,” Pamela Hill, director of clinical services with Addiction Services of Thames Valley, said of the scientific discovery. However, she also stressed that addiction has psychological and social dimensions as well, such as poverty and homelessness that may be either precursors of the addiction or caused by the addiction. “Typically people have focused on the reward part of addiction at the neuro-biological level but there also has to be a way that really powerful experiences like drug use get remembered, and so it looks like these researchers have been able to articulate how memory processes occur in the brain related to opiate use,” Wayne Skinner, deputy clinical director addictions at the Centre for Addiction and Mental Health, said.

The Canadian Federation of Students’ general assembly may not need as many nametags next year, as a group of students is attempting to lead a mass exodus from the lobby group. According to a press release from the student leaders spearheading the campaign, their goal is to “end the Canadian Federation of Students’ control over local campus affairs, [and] to begin discussions about alternatives for provincial and national organizing that keep decision-making power in the hands of students.” “Initially we identified that CFS is a largely ineffective organization,” Ashleigh Ingle, a student from the University of Toronto and one of the leaders of the initiative, said. “Whether it is lobbying efforts or mobilizing students, they were not doing a very good job.” “What was more distressing to us was that when we tried to get more involved in order to positively affect the rest of the organization, we found a lack of financial transparency and democratic procedures that were questionable and highly controlled by long term staff,” Ingle said. “That is what made us decide that the best course of action was to leave.” Brent Farrington, internal coordinator for CFS, argued against this characterization, arguing the students simply disagreed with the majority opinion in the organization. “The membership voted a number of times on proposals from these individuals, and did not give them majority support,” Farrington said. “If that’s not a democratic process I don’t know what is. There is a difference between democracy and getting your way.” Leaving the federation would require each school attempting to leave to complete a lengthy process,

Whether it is lobbying efforts or mobilizing students, they were not doing a very good job. — Ashleigh Ingle,

student leader

which begins with a petition signed by 20 per cent of the student body and a subsequent successful vote on the issue. “My hope is that through this process of ‘defederation’ people begin to think about the alternatives they want to see [and] we can begin a conversation on those alternatives,” Ingle explained. This would not be the first instance of a large exodus from CFS. In 1995, five student unions, including Western’s University Students’ Council, left the CFS and set up the Canadian Alliance of Student Associations. “A lot of us don’t see CASA as an alternative, which is why we decided to create a new organization,” Ingle said. “Many students have asked us about alternatives, and I think that will have to be a longer conversation.” Farrington said the organization is trying to focus on its lobbying efforts and not the “defederation” initiative. “As a membership-based organization we stand by the actions that our members have adopted as priorities,” he said. “We’re building an affordable and accessible system for post-secondary education and that is our priority and will continue to be our focus.”


Turn static files into dynamic content formats.

Create a flipbook
Issuu converts static files into: digital portfolios, online yearbooks, online catalogs, digital photo albums and more. Sign up and create your flipbook.