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THURSDAY, MAY 2, 2013

VOL. 91 | NO. 18 | $4.25

WILD ROSE THREAT | P19

SERVING WESTERN CANADIAN FARM FAMILIES SINCE 1923

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WWW.PRODUCER.COM

SPECIAL REPORT | GENETICS

WEATHER | FLOOD RISKS

RNA interference technology could be farming’s next big thing

Flood risks ease in some areas, rise in others

Advancements in gene suppression | RNAi could be alternative to chemical pesticides

Cooler weather slows snow melt in Sask., Man. BY KAREN BRIERE REGINA BUREAU

BRANDON BUREAU

Monsanto’s chief technology officer hinted in a quarterly earnings call with financial analysts in January that the company might be onto something big. After running through routine updates on corn breeding, soybean yield improvements and other projects, Rob Fraley’s enthusiasm spiked when he began talking about Monsanto’s research and development work on RNA interference (RNAi) for pest management. “These (tools) can precisely target pests and can result in many of the same benefits we’ve seen with biotechnology traits,” he said. “So while it’s still in early stages, I have to emphasize that for me this is a really exciting advance, and it reminds of when I first saw the Roundup Ready technology in the late 1980s.” RNAi could prove to be an alternative to chemical pesticides in insect and disease control. Monsanto’s website describes RNA interference as a process to turn down or shut off the expression of certain genes, which suppresses the production of a specific protein in an organism. In the case of crop pests, RNAi could potentially shut down proteins related to metabolism or reproduction, thus killing or disabling target insects. “We can actually feed these RNA molecules to insects, and they will just ingest them. It will get into the cell and do its job,” said Eric Jan, associate professor of biochemistry and molecular biology at the University of British Columbia, where he is part of a team using RNAi to

PRAIRIE SEEDING INTENTIONS | PAGE 6

RNA interference technology could be tailored to kill a specific pest while beneficial insects are unaffected. | MICHELLE HOULDEN ILLUSTRATION

treat viruses that affect bees. Monsanto and Syngenta have committed large sums of money to RNAi technology over the last 12 months. Syngenta bought Devgen, a Belgian rice breeding company and a world leader in RNAi crop protection, for $523 million last fall, while Monsanto paid $29.2 million last year for exclusive rights to use the intellectual property of Alnylam Pharmaceuticals, a major player in the RNAi industry. This year, Monsanto spent $35 million to acquire Rosetta Green, an Israeli company that improves plant traits with RNA interference. “I think it’s very apparent to these companies … that this is a powerful technology, so investing early and getting a foothold in it (is essential),” said Doug Macron, who reports on gene silencing technology for GenomeWeb, an information service for scientists and tech professionals. “These companies know the science and they’re careful with their money. There’s a reason why they are spending millions of dollars.” Since the discovery of RNA interference in the late 1990s, biologists have primarily focused on gene silencing in humans and potential therapeutic treatments for diseases such as diabetes and cancer. Yet, applying RNAi to human health has proved difficult. “Delivery (of double stranded RNA) has been the biggest hurdle facing the human therapeutic side. Just getting these things into cells and functioning … is terribly complicated,” Macron said. SEE RNAi HOLDS PROMISE, PAGE 2

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YARA EXPANSION PLANS UNCERTAIN | PAGE 84

Better water, better glyphosate

Preparing for the worst

Most of the ground water in rural Western Canada contains calcium, magnesium and iron molecules that could deactivate glyphosate, rendering spraying more expensive and possibly a waste of time. | Page 76

North American authorities continue to plan for the possibility of a footand-mouth outbreak with strategies that involve slaughter, surveillance and biosecurity. | Page 80

Cooler weather forecast ahead of much warmer temperatures for the weekend of May 4-5 could ease the flood risk in some parts of Saskatchewan, provincial officials said April 29. Water Security Agency spokesperson Patrick Boyle said warmer temperatures late last week produced quick increases in outflow on tributaries and resulted in localized flooding. “In those areas where the runoff has started, (the cold weather) will allow flows to pass somewhat before any further snow melt happens,” he said. “So that’s going to help alleviate the peaks.” The situation in Manitoba is similar after cooler weather there also mitigated flood risks in the Red River Valley. Forecasters said flooding in the valley will likely be comparable to 2006, which is below levels seen in 2011 and well below 1997, Manitoba’s flood of the century. SEE FLOOD RISKS, PAGE 2

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u|xhHEEJBy00001pzYv,:) MAY 2, 2013 Return undeliverable Canadian addresses to: Box 2500, Saskatoon, SK. S7K 2C4 The Western Producer is published in Saskatoon by Western Producer Publications, which is owned by GVIC Communications Corp. Publisher: Shaun Jessome Publications Mail Agreement No. 40069240

BY ROBERT ARNASON


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